LOCUS       NZ_CP045480            22571 bp    DNA     circular CON 15-AUG-2024
DEFINITION  Amycolatopsis sp. YIM 10 chromosome, complete genome.
ACCESSION   NZ_CP045480
VERSION     NZ_CP045480.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. YIM 10
  ORGANISM  Amycolatopsis sp. YIM 10
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Complete genome sequence of Amycolatopsis sp. YIM 10, isolated from
            a rare earth mine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2019) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009429145.1-RS_2024_08_15
            Annotation Date                   :: 08/15/2024 04:03:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,775
            CDSs (total)                      :: 9,711
            Genes (coding)                    :: 9,634
            CDSs (with protein)               :: 9,634
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 22 of 77
            Pseudo Genes (incomplete)         :: 65 of 77
            Pseudo Genes (internal stop)      :: 1 of 77
            Pseudo Genes (multiple problems)  :: 11 of 77
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 9827386
            Orig. end                         :: 9849957
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045480.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22571
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="36"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22571
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22571
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12571](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12571)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(1419..2057)
                     /locus_tag="YIM_RS45695"
                     /old_locus_tag="YIM_45865"
     CDS             complement(1419..2057)
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030774.1"
                     /locus_tag="YIM_RS45695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45865"
                     /product="response regulator transcription factor"
                     /protein_id="WP_153036263.1"
                     /transl_table=11
                     /translation="MIKVIVADDQQAVREGLAALLGMAGDVLVTGTAANGRQVLDLLTA
                     GTEADVVLMDLRMPVLDGVGATTLITAEHPGVAVVVLTTYADDESIGGALRAGARGYLT
                     KDAGRTEIATALRCAVAGQSAFDPAVTQRLVEALDSPPPASRVPPDRLTAREAEVLGLI
                     GGGLTNAEIAAKLFIGETTVKTHINNAFAKIGVRNRAEAVRYAYRHELG"
     gene            complement(2054..3169)
                     /locus_tag="YIM_RS45700"
                     /old_locus_tag="YIM_45870"
     CDS             complement(2054..3169)
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030773.1"
                     /locus_tag="YIM_RS45700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45870"
                     /product="sensor histidine kinase"
                     /protein_id="WP_153036264.1"
                     /transl_table=11
                     /translation="MKSSGGIAPSWVIIQGLGTVLIAFFLIVSDDRNPWVWAGYALAAA
                     AWLVFVATLGRRPRLAVPMLAVSTATAAALAGPATGVTATVITLLTIGRFAGLTIASGR
                     LIGVVVGLDLVLVIGGCLLWDRPAWDVGGATAAVLVSALCGLNRRQTDLRVAQTEQLLE
                     QTRLAHAEHARAAALDERTRIAREIHDVLAHSLGALGVQLELAEALLAERDDREAALTT
                     IRRSRRLAVDGLGEAREAVAALRQDLPSLPEAVTRLVEVHRRDRGPVELDLCGEVVAVP
                     TVATVALTAVAREALTNAAKHAPGARVEVVLHSGDQGVRLEVGNGVPPGHGRGKGFGLT
                     GMRERLELAGGTLNAGPDGGDRWLVTAEVRR"
     misc_feature    3123..3141
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.22"
                     /tool="antismash"
     misc_feature    complement(3124..3142)
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 19.3"
                     /tool="antismash"
     gene            complement(3300..3503)
                     /locus_tag="YIM_RS45705"
                     /old_locus_tag="YIM_45875"
     CDS             complement(3300..3503)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222289.1"
                     /locus_tag="YIM_RS45705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45875"
                     /product="cold-shock protein"
                     /protein_id="WP_153036265.1"
                     /transl_table=11
                     /translation="MTQGTVKWFNSEKGFGFITPDNGGGDVFVHYSEIQGNGFRTLEEN
                     ARVEFEIGQGQKGPQATSVNLI"
     gene            complement(3749..3925)
                     /locus_tag="YIM_RS45710"
                     /old_locus_tag="YIM_45880"
     CDS             complement(3749..3925)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS45710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_45880"
                     /product="hypothetical protein"
                     /protein_id="WP_153036266.1"
                     /transl_table=11
                     /translation="MGNETAGHPARTSGVAPVAFSNTEAPEPIKSMTSAADRDAVTRSP
                     FSAEAAGSRRTGE"
     gene            complement(4028..5665)
                     /locus_tag="YIM_RS45715"
                     /old_locus_tag="YIM_45885"
     CDS             complement(4028..5665)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055: pyruvate oxidase/decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009071745.1"
                     /locus_tag="YIM_RS45715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45885"
                     /product="thiamine pyrophosphate-binding protein"
                     /protein_id="WP_153036267.1"
                     /sec_met_domain="TPP_enzyme_N (E-value: 9.9e-45, bitscore:
                     151.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.9e-38, bitscore:
                     130.2, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLTVARTVVRLLAEAGVRRAYAIPGESVVDLLEALQVEPRLNLI
                     SARHEAGAAFMADADGKLCGTPAVAVAGSGPGATGMTAAVHTAFQDETPMVVLLGQVPS
                     GDLGEETFQEVDLVRLYAPLAKWTAEATTPDEVPGLLAEALHAVNTGRQGPAVLSVPAD
                     FWARPFESVVQRPAEVVVPPGSLERLAGEVARLVDDARYPVIIAGGGVRLARKQLIDAV
                     DHLGLAVYTAFRRQDAFPENHPNYVGHLGHGVPDDQLRALEQADLVLALGTRLDEVTTQ
                     RYRYPAYTQPLVMVGGGRPGPRRRGLTFHVDTDVARFLSELRQAAKPRKRNWTVAHQAV
                     KEFMRLPQRGTSGPVHPADVVRSLRQLAPEDTVVTTDAGNFAAFVHRYWCFTQPRTQLG
                     PCNGAMGYAVPAAVAAKLAEPHRTVVAMVGDGGALMTGQEIETAVRHRAPVIVVVFQNG
                     LYGAIAAHQARSHGRLSSVAVGTVDFASWARGLGAAGYTVNDQEELEPALASALMRQRP
                     CVVDVRTDPDVIAPDQRLSTMLRSRLES"
     misc_feature    complement(5749..5766)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.42"
                     /tool="antismash"
     gene            complement(5781..6320)
                     /locus_tag="YIM_RS45720"
                     /old_locus_tag="YIM_45890"
     CDS             complement(5781..6320)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS45720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_45890"
                     /product="hypothetical protein"
                     /protein_id="WP_153036268.1"
                     /transl_table=11
                     /translation="MTAETDGNPFDGGVSWDRRGEHWVGVFHPGYLSLFREHIATLRGI
                     IRRRLDQHAAGLPELEPDPRVAAILRLRDGAGLSELEILFPVVNRLAEVEAEVPETGGV
                     VELRGWEDRYRWGSAALDVCIAITEWVQRWSRGEQVDGAHCPDPAALVLWSRQCEWLNE
                     HIVVPLRPLVDPAPEG"
     gene            complement(6330..8051)
                     /locus_tag="YIM_RS45725"
                     /old_locus_tag="YIM_45895"
     CDS             complement(6330..8051)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077513.1"
                     /locus_tag="YIM_RS45725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45895"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_153036269.1"
                     /transl_table=11
                     /translation="MSITKLYWGSLGRQWRGGLVLFGCSVLESVPAFLSGRLVALAVDR
                     GFAAGDPLTGVLWLLVFALVAVIGALGSRLVWRQLGMVIEPIRDALVTAVVSGILRNGA
                     TSRNAPDASGVARITQHVEVIRDATAGLLVQARGMLVTTVAALAGLFTVAGGLAWLVAV
                     PVLTALVLFACLLPALAARQRAVAIADERTAEVAGGVLVGMRDVVACGAEQTAGMAVFD
                     AVDDQARAAVRMAQATAMRTLVIAIGGFSPLVLVLLNAPGMVAAGELTAGAALGSLVYL
                     ATTMQPALQGLASTASTVVLRLLVAVRRLSEVAGEPPEAGGGAEPAGAAISVRGLTFGW
                     GEHAEPVVRGLDLDLVPGDHLAVVGPSGIGKSTLAGLLTGQLEPQDGLVRLGGVPVRSV
                     RPEVVHRMVALIPQEAYVFAGTVRENLALLAPEATDERLYEAARAVGAGDLVDRLGGLY
                     GEIGHAAEGLSAGQAQLLGLARVYASQAEVIILDEATAHLDPAAEAHAERAFAARGGIL
                     VVIAHRLSSALRANRLLVMDGDHTLLGTHEGLLAESARYAEMMRAWTGTPERVRAS"
     gene            complement(8048..9712)
                     /locus_tag="YIM_RS45730"
                     /old_locus_tag="YIM_45900"
     CDS             complement(8048..9712)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020642934.1"
                     /locus_tag="YIM_RS45730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45900"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_153036270.1"
                     /transl_table=11
                     /translation="MRGDRLLAEVAGGDRARLGLVLLTALTATTAGLLLPGALAGAVDA
                     AISGQRSWPQVLLLLGLGALDITADVLGGLLTVAVTSTATAALRRRLTRHLLGLGTRSR
                     FADGDAISRLTGDCVSAGSVASILVQLGSAACLSVGAIVLLAVLDWRLALVFLGSVPIA
                     LWLARSHLRNTADDVLTYQRVSGEISARLLDAVRGLRTIAASGTADRETRRVLRPLPEL
                     GKAGSGMWQTQARMIWRAALLLPAVEVAVLIAAGFGVLNGRLSVGDVLAALGYVALGMG
                     LVGQIPLLTTLARARSCAQRISEVLDEPLPHRGRADVRPGPGSVELRRVTVPGALSEVD
                     LTIPGGTFLAVVGKSGSGKSALVGVVGGLIRPEEGRVLLDGVSTGRLRPEVLRYYVAYA
                     FERPALLGGTVAEAVSYGTWAGEIAVRNACRAAQVHDLVVRLPDGYRTPLAETPLSGGE
                     AQRLGLARAIVRNPRVLVLDDATASLDTVTEVRVDEAIETALPGRTRLVVTHRAGTAAR
                     ADLVAWLENGRVRAVGPHDVLWREPGYRAVFTEEAEQ"
     gene            complement(9832..9978)
                     /locus_tag="YIM_RS45735"
                     /old_locus_tag="YIM_45905"
     CDS             complement(9832..9978)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009949109.1"
                     /locus_tag="YIM_RS45735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45905"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_153036271.1"
                     /transl_table=11
                     /translation="MELVLDLQAMEDTEGPQFGGGSGGGGGGSNLSLLASCNNSTVSLL
                     TCH"
     CDS_motif       complement(9913..9978)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MELVLDLQAMEDTEGPQFGGGS"
                     /locus_tag="YIM_RS45735_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9832..9912)
                     /prepeptide="core"
                     /locus_tag="YIM_RS45735_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="3.00"
                     /molecular_weight="2293.5"
                     /monoisotopic_mass="2292.1"
                     /core_sequence="GGGGGGSNLSLLASCNNSTVSLLTCH"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MELVLDLQAMEDTEGPQFGGGS"
                     /leader_location="[9912:9978](-)"
                     /alternative_weights="2311.5"
                     /alternative_weights="2329.5"
                     /alternative_weights="2347.6"
                     /alternative_weights="2365.6"
                     /alternative_weights="2383.6"
     gene            complement(10001..12571)
                     /gene="lanKC"
                     /locus_tag="YIM_RS45740"
                     /old_locus_tag="YIM_45910"
     CDS             complement(10001..12571)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013222285.1"
                     /locus_tag="YIM_RS45740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45910"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_153036272.1"
                     /sec_met_domain="micKC (E-value: 0.0, bitscore: 1269.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 4.1e-09, bitscore: 35.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 3e-05, bitscore: 23.2,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.7e-11, bitscore:
                     42.0, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLRYEAFCFADPLFFDEQRDDGQAKDDFAAVLPSLGSEWRSGER
                     GIWRSLSPADAVLPAQGWKIHVSAGMANAERVLLAVAAYCVEQRIAFKHLRSRSILLAR
                     NSKYAPRDGSGKLITIYPPDEESLQRVLSDLSAELQGEVGPYILSDLRYGEGPLYARYG
                     GFAEQWVEADGTRVLAISKPDGTLVPDKRGPSFHVPDWVELPECLEPHLAARKGGDPAQ
                     FPYKVTKSLHFSNGGGVYLANRLADDREVVLKEARPHAGLDRDLVDAVARLEREHRILE
                     RLAGIPGIPEVYDRFQVWEHHFLAMQFVPGKPVGAWLARNYPLTRRDATEQDVAEYTER
                     ALALIGRVERLVAAVHERGVVFGDLHALNILVDDNNDDTVSLIDFELAAGIEEETKPAL
                     GAPGFRAQRDRTGFEIDEYALAALRLWLFLPLNTILELAPAKLASLVDFAERRFPLPEG
                     YGRRILDVLSPRGDAEVRPAVTQLDEPKPDWAVVRKSIATAILASATPDRQDRLFPGDI
                     QQFEVGGLGFGYGAAGVLHALHAAGEGRYPEHEQWLLDAVRRTPPSRPGFYDGTHGIAY
                     VLENFGHHDRADELIAASRHLVEITTDHNLEGGLAGIGLNYLHFAGTRRDADFERTAVT
                     IGERLGNALATDAGPLKFARAGLMSGWSGPALLFVRLFEATGDQAWLDLAAKAVERDLE
                     ECVPADDGSLQVRDGESRTLPYVGMGSAGVALAAEELAAHRPDADCLEKLPRLLDACRG
                     EFVIHPGLMLGRAGLMATLSAEARRTGDPVALAAVDLHLSRFAWYALPYRDGLAFPGNQ
                     LLRLSMDLYTGGAGVLLALAATLDGHGAVLPFLSPGPRSSTAGG"
     misc_feature    12585..12599
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.32"
                     /tool="antismash"
     misc_feature    complement(12731..12748)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.63"
                     /tool="antismash"
     misc_feature    complement(12793..12807)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 18.38"
                     /tool="antismash"
     misc_feature    complement(12849..12862)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.89"
                     /tool="antismash"
     gene            complement(12908..13552)
                     /locus_tag="YIM_RS45745"
                     /old_locus_tag="YIM_45915"
     CDS             complement(12908..13552)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946255.1"
                     /locus_tag="YIM_RS45745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45915"
                     /product="molybdopterin-dependent oxidoreductase"
                     /protein_id="WP_153036273.1"
                     /transl_table=11
                     /translation="MPALPPGQWPAARQRFGLPEFHRVRPEVPARPVVTVTGVVRRPVQ
                     LELAELLGGPGREQISDLHCVTTWSALSLRWGGVPFREVHEVLRRRVEPHPKCRWVVFA
                     GLDGFRSCLALDDALAADVLLADSLAGQPLDADAGAPLRLVAPAHYGYKSVRHVCAIEY
                     VTSYDGGSAGWKAHRRGRVELEERSALLRGRIWRPLFRRFVPVGTSAATGD"
     gene            13865..14185
                     /locus_tag="YIM_RS45750"
                     /old_locus_tag="YIM_45920"
     CDS             13865..14185
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016337350.1"
                     /locus_tag="YIM_RS45750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45920"
                     /product="winged helix-turn-helix domain-containing
                     protein"
                     /protein_id="WP_153036274.1"
                     /transl_table=11
                     /translation="MPETGDALLRTLTALANPHRLRVIGALAGGRQYVSKLARELGISR
                     PLLHMHLQRLEAAGLVVGTLETGEDGKLMKYFEATEFALSLSPATIAAAVPTLSERPGE
                     DR"
     gene            14182..14424
                     /locus_tag="YIM_RS45755"
                     /old_locus_tag="YIM_45925"
     CDS             14182..14424
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS45755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_45925"
                     /product="hypothetical protein"
                     /protein_id="WP_153036275.1"
                     /transl_table=11
                     /translation="MTWQETTITMVSIIFGMALVIVVVLQLSKIISTVASARRERVLRE
                     LAVELRAGQDHLSAEVAEIRRIVEETERRVREVDY"
     gene            14542..15267
                     /locus_tag="YIM_RS45760"
                     /old_locus_tag="YIM_45930"
     CDS             14542..15267
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009155450.1"
                     /locus_tag="YIM_RS45760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45930"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_153036276.1"
                     /transl_table=11
                     /translation="MSSLSMLPARAGVYTTSIAHTAEQLRAAQRLRHRVFAGELGARLD
                     GELDADEFDRFCDHLIVEHEPTGEVVGTYRLLPPGRSDFLYSQGEFELGALDPLRSSLV
                     ELGRSCVHPDHRGGAVIGLMWTAVARYAHLSGNRYLAGCASVPLGDGGMAAASTLALSE
                     KHAGPYEVTPHLPWIPSVAGRPSYAQVPPLLRGYLRLGAWICGKPAHDPDFDVADFFIL
                     LPLDRIDDRYLRYFLGAAQ"
     gene            15402..15980
                     /locus_tag="YIM_RS45765"
                     /old_locus_tag="YIM_45935"
     CDS             15402..15980
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009152196.1"
                     /locus_tag="YIM_RS45765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45935"
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_228004422.1"
                     /transl_table=11
                     /translation="MRALDVDVEHSAYTPSEPGTLVVANHISWLDIPVMLALDSAVFLA
                     KREVARWPFVGGLAMRSGTLFIDRHSYRGLPRTVAELARTLRSGRSVVVFPEATTCCGV
                     HSAPFRRAAFQAALDAGAPIQPVRISYHQGDAPSTVPAFLGDDTLLTSVRRVLRARELR
                     VRVSSSPLLEPFGDRRRLAALAQHPCLIS"
     gene            15965..16600
                     /locus_tag="YIM_RS45770"
                     /old_locus_tag="YIM_45940"
     CDS             15965..16600
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1188: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030848.1"
                     /locus_tag="YIM_RS45770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45940"
                     /product="DedA family protein"
                     /protein_id="WP_153036278.1"
                     /transl_table=11
                     /translation="MLDLLNSFAELVSGALGSPWLWVVVFFVSALDALLPFMPSETTVI
                     TVAVLLGQAAGSLVALAVLAAAGALAGDCLSHAIGRRAGPRALARLQRGERGQRRYEWV
                     RDKLARHGPTLIIAGRYLPGGRVAVGLATGSLRYPLRRFVALDALGASIWAVYSVLVGY
                     LGGASFAGNPAMGLLVAFGIGLATVGLVELGRRHYARRRDRVDQASPT"
     gene            complement(16582..17337)
                     /locus_tag="YIM_RS45775"
                     /old_locus_tag="YIM_45945"
     CDS             complement(16582..17337)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS45775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_45945"
                     /product="hypothetical protein"
                     /protein_id="WP_153036279.1"
                     /transl_table=11
                     /translation="MTAQPTLPPPMMPQAKPAKFAALAWSSLILGIVGVLGSPIIFLNN
                     LTAVVAGVGFILGAIALFGSKKILAGIGVALCVAGIVFTVIAQQAAVEKLDEILNGTTD
                     QGRVADAGRGEGGVPADAPTWGKRYTWESGLAVDVAAPAACKPSDTAAPPNIERAVKIT
                     VTVTNGTSEPFDATLLSLGGDAQFGGAKADQIHDFGGECGGGLESATVLPGKTFTYSVA
                     YAVGPQPGEMQIAFQPTFGADKAIYVGDA"
     misc_feature    17366..17380
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.26"
                     /tool="antismash"
     gene            complement(17460..18041)
                     /locus_tag="YIM_RS45780"
                     /old_locus_tag="YIM_45950"
     CDS             complement(17460..18041)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009948155.1"
                     /locus_tag="YIM_RS45780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45950"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_153036280.1"
                     /transl_table=11
                     /translation="MRTVNPEQHARRRAEILAAAAQEFAAAGVDGTSTADICRRAGIGS
                     GTLFHYFPTKREIFHALFRDDQVRDAEVCERALAADDPATGVRQVAEHLMADLADPLIP
                     GLMAAALLQINQDQEFAEMIEANELRIRATLTELLGRLDSARLAFAPERVAVWIQRVAD
                     AAFLAADEEGFNPAEQLAEFRTFLTWLLGD"
     gene            18087..19094
                     /locus_tag="YIM_RS45785"
                     /old_locus_tag="YIM_45955"
     CDS             18087..19094
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946221.1"
                     /locus_tag="YIM_RS45785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45955"
                     /product="hypothetical protein"
                     /protein_id="WP_153036281.1"
                     /transl_table=11
                     /translation="MDVRGISYTVADTDPAEDLRTIREELHCTTVLLAGTDAAKQLRAA
                     EKALALGLDVWIEPQIGDRPFDDVLAWIAEAAAGAEELRARYPGRVTLVVGCEYSLRLS
                     GMIPGPREFIRLQVLIRWPRKWRARSSVEGGGGLAGGLFDRRITRVLNRRLARSVAVAR
                     GAFHGPITYAAGYWEQVDWSPFDLVGVNLYRMGDNREAYEDRLRELVRSTDKPVVITEF
                     GCGAFTGADRRGPASFLIVNWFTSPPRIRDGHVRDERTQAAYLGELIELYEREDVHGAF
                     VFTYWMPDFPHHPDPALDLDMAGFGVVKVTADGKRVPKEAFTEVAHRYSATTAS"
     misc_feature    complement(18115..18129)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            19122..20759
                     /locus_tag="YIM_RS45790"
                     /old_locus_tag="YIM_45960"
     CDS             19122..20759
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_function="GO:0140662 - ATP-dependent protein folding
                     chaperone [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012242.4"
                     /locus_tag="YIM_RS45790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_45960"
                     /product="Hsp70 family protein"
                     /protein_id="WP_194239967.1"
                     /transl_table=11
                     /translation="MRELAVDFGTSNTVAALRANGGPSRLLLFDGWPVLPSAVLRGRDG
                     GLVVGREALRGARLDPARFEPHPKERIDEGEVLLGDAAVPVVSLIAAVLRRVAAEAPAP
                     DRVVLTHPADWYSSRRAVLLAAAREAGWQGEVQLVAEPVAAASQAADVPPGQAVAVFDM
                     GGGTTDVAVLRRTSTGWDVLAEAGLPDFGGRDLDQLLLDHLGVEVDPTADAAGRRAARV
                     LAEDVRAGKEALSQYPQTDIPLPAPRPDAHLTRQELETLVEAALRRAVDLLAETVGTTS
                     LTAVHLVGGATRMPLVARLISERLGLVPTIVESPETSVALGALGPPPRPQRTPFPPPPL
                     PRSTPMPPPPPEERKKPPVAAITTAIVVTLLAAGGVIAAALLRPDTVGTAVVGPTPSAP
                     PDNPAFRGDEPLIAFAGPAAGKADECVNVMGTASQGDQYSARNHVRCRFEIDGIAYFAN
                     YLSADGPQTCGQLNEEFLELPGAQWLSEDPWTGGDLRGKSHDVAATSGNNVLWYTDTNT
                     LCAFFGASTDQNPPMSEVHQAWETVVGA"
     misc_feature    complement(21728..21743)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     misc_feature    22343..22357
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.34"
                     /tool="antismash"
ORIGIN
        1 tctcgtccat ccgcaggaag gcgccggtgg agccctcggc ctgccgctcg tcgatggcca
       61 ggctgaccgc ttcggcgtac ttgcctacgt cgtcgttctc ccgcaccttg cggtgcgcct
      121 gcagccagac gccggcctcg gtgatcgcgc ggtcgacctg ctcggtgttc cccgcgtcgg
      181 cggccagtga gcgcagctcg ccgagcaggc cgcccttgcc gtcctggccg accatcttcg
      241 tggtcagctc ggtgaactcc ttctcgtact tggccccgtc cccgcgcgcg accagcgtga
      301 gcgtctcgtc ggcgcgggcc tgctgcgcgg agatccgcgc ctgcaccgcg agatccacct
      361 ggcgggtgcc gttctcgctg ccgctgccga ccgcgatgcc ctgcaccacc agcgccaccg
      421 cgctccagag cagcgcgagc accaccgcgc cggtggccac cagcaggccg acgttgagca
      481 cgcggttcgt ccggcgcttg aggtagacct gggtggcgat cagcgagccg agcagggcga
      541 gcacgagcac gccggccacc cacggcacgt cggtggcgtc gtcctgctcg gtcatcaacc
      601 gctcggtgtc gatgcggtac agatcggccg cggcgggcag gatcttcgtc cgcatcagct
      661 cggacgcctc gcgcaggtag gaggcaccgg ccgggaagcc ctggcggttg ttcgcgcgag
      721 ccgtctcgat cagcccggtg tagaccggga actgctggtt gatcacgtcc acctgggcag
      781 ccgcctcggg cacgccgccc gcgtcggaag ccgccttcgc cagcgcggag ccggcctgcg
      841 ccacgtccag ctcgtaccgc gagcgcaggg cgggcggctc ggtgccggtg gccaggaagg
      901 cgctggccgc ggtcgcgtcg gcgtccgaga gcgagcggta cacctgctgc gccgccaccg
      961 ccagcggttc gcggtggtcg atcagctcgt tgatggtgtc ctttttgccc tgcaccgaga
     1021 tcgcgccgat gatgccggtg atcagcgcga gcagcaccag gccgaccgcg atcaccgtca
     1081 accggccggg ggtggcggcc gccgaccgga ccaccgcgcg cacggccagt cccggcagcg
     1141 cgaaaagtcc ggcgagcccg gtgcgcgtct ccgccgcgcg tggcggcggt tcccctcccg
     1201 gcccgcgcgg cggcccggag ctgggcggcc gggcgggcgt cgccacgctg ccggtgctac
     1261 cggtgctcgt catcggattc ctccacccct cctacgtccg ggcatgaacg tataggagat
     1321 accgcgaccg gtaccaccga cctgcgggcc acaaccgaaa ttttggccgc gccttcggca
     1381 cggcggcgag gtcgctttga gcgacctcgc aatcgaaatc agcccagctc gtgccggtac
     1441 gcgtagcgca cggcttccgc gcgattgcgg acgccgatct tcgcgaaggc gttgttgatg
     1501 tgcgttttga ccgtggtttc cccgatgaac agcttggccg cgatctcggc gttggtcagc
     1561 ccgccaccga tcagccccag cacctccgcc tcgcgggcgg tcagccgatc gggcggtacg
     1621 cgcgaggcgg gcgggggcga gtcgagcgct tcgaccaggc gctgggtcac cgccggatcg
     1681 aaggccgact ggccggccac cgcgcaacgc agcgcggtgg cgatctcggt ccgcccggcg
     1741 tccttggtca ggtagccgcg ggccccggcg cgcagcgcac cgccgatcga ctcgtcgtcg
     1801 gcgtaggtgg tcagcaccac caccgcgacg ccggggtgct cggcggtgat cagggtggtc
     1861 gcccccaccc cgtcgagcac cggcatgcgc aggtccatca gcaccacgtc ggcctcggtc
     1921 ccggcggtga gcaggtcgag cacctggcgg ccgttcgcgg cggtgccggt caccagcacg
     1981 tcaccggcca tgccgagcaa cgcggccaat ccctcgcgca ccgcctgctg gtcgtccgcg
     2041 acgatgacct tgatcatctc cgcacttccg ccgtcaccag ccatcgatct cccccgtccg
     2101 gtcccgcgtt cagggtgcca ccggccagct ccagtcgctc gcgcatcccg gtcagcccga
     2161 agcccttccc ccggccgtgc cccggcggca ctccgttccc cacttcgagg cgaacgccct
     2221 ggtcaccgga gtgcaacacc acttcgacgc gggcgccggg agcgtgcttg gccgcgttgg
     2281 tcagcgcttc gcgggcgacc gcggtcagcg cgacggtggc caccgtcggc accgcgacca
     2341 cctcgccgca caggtccagt tcgaccgggc cgcgatcgcg ccggtgcacc tcgaccagcc
     2401 gggtcaccgc ctccggcagc gacggcaggt cctggcgcag cgcggcgacc gcctcgcgtg
     2461 cctcgccgag gccgtccacc gccagccgcc gcgaccggcg gatcgtggtg agcgcggcct
     2521 cgcgatcgtc gcgctcggcc agcagcgcct ccgccagttc gagctgaaca cccagcgcac
     2581 caagggaatg cgcgagcacg tcgtggatct cgcgggcgat gcgggtgcgt tcgtcgagag
     2641 ccgcggccct ggcgtgctcg gcgtgggcga ggcgggtctg ttcgagcagt tgctcggtct
     2701 gcgccacgcg gagatcggtc tggcggcggt tcagcccgca cagcgcggag accagcaccg
     2761 cggcggtcgc accgccgaca tcccaggccg ggcggtccca gagcaggcag ccgccgatca
     2821 ccagcaccag gtcgaggccg acgaccacgc cgatcagcct gccgctcgcg atggtgagcc
     2881 cggcgaagcg cccgatggtg agcaaggtga tgaccgtcgc ggtcacgccg gtggccggac
     2941 cggccagcgc agcggccgtc gcggtcgaaa cagccagcat cggcacggcg agccgtgggc
     3001 gcctgcccag ggtcgccaca aaaacgagcc aggccgcggc cgcgagcgcg tacccggccc
     3061 agacccacgg gttccggtcg tcggagacga tcaggaagaa ggcgatcagt accgtgccga
     3121 ggccctggat gatcacccag gacggcgcga tgccaccgga agacttcacc tgatcagact
     3181 aggacggcac ccggctcgcg ggacccgccc gaaggtggag atcagggtgg agatacggcg
     3241 aaggggccgc caccggtagc acggtgacag ccccttcgtc gaagagctga gggtcagtct
     3301 cagatgaggt tgaccgaggt ggcctggggg cccttctggc cctggccgat ctcgaactca
     3361 acgcgagcgt tctcctccaa cgtgcggaag ccgttgccct ggatctccga gtagtgaacg
     3421 aagacgtcgc cgccgccgtt gtcgggagtg atgaagccga accccttctc ggagttgaac
     3481 cacttcacgg tgccctgagt catataaaac aatctccatg cgtaaaaaca atcgaggggc
     3541 caggccggca ccccgggtca aaacggaacg gtttgcctcc ccgagtgggg aacgcactac
     3601 gcccgctaag tcttgcgagc gtggctgaga agagaacggg tgtcagcacc cagcacgaac
     3661 acaaaagctt gagaccaccg gaagtaaagc acacaaccgg ggccgcccgc cagtgatgag
     3721 cccgtccggg tgatcctcac gacccggctt attctcccgt ccgcctgctc ccggccgcct
     3781 cggccgagaa cggggacctg gtgaccgcgt cccggtcggc cgcgctggtc atcgacttga
     3841 tcggctccgg cgcctcggtg ttgctgaagg ccaccggcgc cacgccggag gtcctggccg
     3901 gatgccccgc tgtttcgttc cccatgttcg ccaccctctc tcgcggaccc cgtaccgctc
     3961 ggtccgtgtg ccgccgattg tgccacggcg gaccgacaaa aaccggtcag tgagaaggct
     4021 tcgcgcgtca gctctccagg cgcgaccgga gcatggtgct caaccgctgg tcgggggcga
     4081 tcacgtcggg atcggtgcgc acgtcgacca cgcacggccg ctgccgcatc agcgcgctgg
     4141 ccagcgccgg ctccagttcc tcctggtcgt tgacggtgta cccggcggcg ccgagacccc
     4201 ttgcccagga agcgaaatcc accgttccga cggccaccga ggacaaccgg ccgtgcgacc
     4261 gcgcctggtg cgcggcgatc gcgccgtaca gcccgttctg gaacaccacc acgatcaccg
     4321 gggcccggtg ccggaccgcg gtttcgatct cctgcccggt catcagcgcg ccgccgtcgc
     4381 cgaccatggc gaccacggtc cggtgcggtt cggccagctt cgcggccacc gcggcgggca
     4441 ccgcgtagcc catcgcgccg ttgcacgggc cgagctgcgt gcgcggctgc gtgaagcacc
     4501 agtaccggtg cacgaaggcg gcgaagttgc ccgcgtcagt ggtcaccacg gtgtcctcgg
     4561 gggccagctg gcgcagcgag cgcaccacgt ccgccgggtg gaccgggccc gaggtgccgc
     4621 gctgcggcag gcgcatgaac tccttgaccg cctggtgggc caccgtccag ttgcgcttgc
     4681 gcggtttggc cgcctgccgc agctcgctga ggaaccgggc gacgtcggtg tcgacgtgga
     4741 aggtcagccc ccggcgccgc ggaccgggac ggccgccgcc gaccatcacc agcggctggg
     4801 tgtaggccgg gtagcggtac cgctgcgtgg tcacctcgtc cagccgggtg cccagcgcga
     4861 gcaccaggtc cgcctgctcc agcgcgcgga gctggtcgtc cgggacaccg tggccgaggt
     4921 ggccgacgta gttggggtgg ttctccggga aggcgtcctg cctgcggaaa gcggtgtaga
     4981 cggcgagccc gaggtggtcc accgcgtcga tcagctgctt gcgcgccagg cgcaccccgc
     5041 caccggcgat gatcaccggg taccgcgcgt cgtcgaccag gcgcgccacc tcgccggcca
     5101 gccgctccag cgagccgggc ggcacgacga cctcggcggg ccgctgcacc acgctctcga
     5161 acgggcgcgc ccagaagtcg gcgggcaccg agagcaccgc gggtccctgg cggccggtgt
     5221 tcaccgcgtg cagcgcctcg gccagcagtc ctggcacctc gtccggggtg gtcgcctccg
     5281 ccgtccactt ggccagcggc gcgtacaacc ggaccaggtc gacctcctgg aaggtctcct
     5341 cgccgaggtc accggatggc acctggccga gcagcaccac catcggcgtc tcgtcctgga
     5401 aggcggtgtg cacggcggcc gtcatgcccg tcgcgccggg gccgctgccc gccacggcca
     5461 ccgcgggggt gccgcagagc ttgccgtcgg cgtcggccat gaaggcggca ccggcttcgt
     5521 ggcgcgcgga gatcaggttg agccggggct ccacctggag cgcttccagc aggtccacca
     5581 cggattcacc gggaatcgcg tacgcgcgcc gcaccccggc ctcggccagg aggcgcacca
     5641 cggtgcgcgc aacggtcaac cccatgcggc gtgccaccct tcggtccgcc cgagcgcggg
     5701 ttatcgtacc cggttccggc cggagacgat caggaaaatt gtgccagtct tactggtgag
     5761 taacaagggt cggaagtcgg tcagccctcg ggtgccgggt ccaccaacgg ccgcagcggc
     5821 accacgatgt gctcgttgag ccattcgcac tgcctgctcc acagcaccag cgcggccggg
     5881 tcggggcagt gcgcgccgtc cacctgctcc ccgcgcgacc agcgctgcac ccactcggtg
     5941 atggcgatgc agacgtcgag cgcggccgag ccccagcggt accggtcctc ccagccgcgc
     6001 agttccacca cgccgccggt ctccggcacc tcggcctcca cctcggcgag ccggttcacc
     6061 accgggaaga ggatttccag ttcggacagc ccggcgccgt cgcgcaaccg caggatcgcc
     6121 gccacccgcg gatccggttc gagttccggc aaaccggccg cgtgctggtc gaggcggcgc
     6181 cggatgatcc cgcgcagggt ggcgatgtgc tcgcggaaga ggctgaggta gccggggtgg
     6241 aacacgccga cccagtgctc gccgcgccgg tcccagctga ccccgccgtc gaagggattc
     6301 ccatccgttt ccgcagtcac ggcggtaggt tacgaggccc gcacccgctc gggggtgccg
     6361 gtccaggcac gcatcatctc ggcgtacctg gcagactcgg ccagcagtcc ttcgtgcgtg
     6421 ccgagcaggg tgtggtcgcc gtccatcacc agtaggcggt ttgcccgcag cgccgagctg
     6481 agccggtggg cgatgaccac cagaatcccg cccctggccg cgaaagcgcg ttccgcgtgg
     6541 gcctcggcgg ccgggtcgag gtgcgcggtc gcctcgtcca ggatgatcac ttcggcctga
     6601 ctggcgtaca ccctggcgag cccgagcagc tgggcctgac cggcggaaag cccttcggcg
     6661 gcatggccga tttcgccgta cagcccacca agccggtcca ccaggtcgcc cgcaccgacc
     6721 gcgcgggcgg cttcgtacaa ccgctcgtcg gtcgcctccg gcgccagcag cgccaggttc
     6781 tcccgcacgg tcccggcgaa aacgtaggcc tcctgcggaa tcagcgcgac catccggtgc
     6841 accacctccg gccgcaccga gcgcaccggc actccaccga gccgcaccag tccgtcctgc
     6901 ggttcgagtt gcccggtgag cagtccggcc agggtcgact tgccgatccc gctcgggccg
     6961 accaccgcga ggtggtcacc ggggaccagg tccagatcca gcccgcgcac caccggttcc
     7021 gcgtgctcac cccagccgaa ggtcagcccg cgtacggaaa tcgccgcgcc cgccggttcg
     7081 gcgccgccgc cggcttccgg gggctcaccg gccacttcgg acagtcggcg gacggcgacc
     7141 agcaggcgca gcaccaccgt gctcgcggtg gacgccaggc cctgcaaagc gggttgcatg
     7201 gtggtggcga gatagaccag cgagccgagc gcggccccgg cggtcagctc accggccgcc
     7261 accatgcccg gcgcgttgag cagaaccaga accaacgggg aaaagccgcc gatcgcgatg
     7321 accagcgtgc gcatcgcggt cgcctgtgcc atccgcaccg cggcgcgggc ctggtcgtcg
     7381 accgcgtcga agaccgccat gcccgcggtc tgctcggcac cgcaggcgac cacgtcccgc
     7441 atgccgacga gcaccccacc ggccacctcg gcggtgcgtt cgtccgcgat ggccaccgcg
     7501 cgctgacgcg ccgcgagcgc gggcagcagg caggcgaaga gcacgagcgc ggtcagcacc
     7561 ggaaccgcca ccagccaggc cagcccgccc gccacggtga acaagccggc gagcgcggca
     7621 accgtggtca ccagcattcc tcgtgcctgc accaggagtc cggcggtggc gtcgcggatg
     7681 acctccacgt gctgggtgat gcgcgcgacc ccgctggcgt cgggcgcgtt ccggctggtg
     7741 gcgccgttgc gcaggatccc gctgaccacc gcggtcacca gcgcgtcgcg aatcggttcg
     7801 atcaccatgc cgagctgccg ccacaccagc cgcgacccca gcgcgccgat caccgcgacc
     7861 agtgcgaaga ccagcaacca cagcacgccg gtcagcgggt cgcccgcggc gaacccgcgg
     7921 tcgaccgcga gcgcgaccag ccgcccggac aggaacgcgg gcacgctttc cagcaccgag
     7981 cagccgaaca ggaccagccc gccacgccac tgcctgccga gcgagcccca atacagtttg
     8041 gtaatgctca ttgctcggct tcctcggtga aaaccgcgcg gtagccgggt tcccgccaca
     8101 gcacgtcgtg cggaccgacc gcacgcaccc ggccgttttc cagccaggcc accagatccg
     8161 cccgcgccgc ggtcccggcc cgatgggtga ccaccagccg cgtacgaccc ggcaacgcgg
     8221 tttcgatggc ttcgtcgacc cgcacttcgg tgaccgtgtc gaggctggcg gtcgcgtcgt
     8281 cgagcaccag cacacgcggg tttcgcacga tcgcgcgcgc caggccgagg cgctgggctt
     8341 ccccgccgga caacggggtt tccgccagcg gcgtgcggta tccgtcgggc aggcgcacca
     8401 ccagatcgtg cacctgcgcg gcccggcacg cgttgcggac ggcgatctca ccggcccacg
     8461 tcccgtacga aaccgcttcg gcgaccgtgc cgccgagcag cgcgggccgt tcgaacgcgt
     8521 aggccacgta gtaccgcagc acctcgggtc gcaggcggcc ggtggacacg ccgtcgagca
     8581 gcacgcggcc ctcctccggc cggatcagcc cgccgaccac accgaccagc gcggacttgc
     8641 cggacccgga tttccccacc acggcgagaa aggtcccgcc cggaatcgtc aagtccactt
     8701 cggacagcgc gccgggcacg gtgacccggc gcagttccac cgaaccggga ccgggccgca
     8761 cgtcggcacg accgcggtgc ggcagcggtt cgtcgagcac ctcgctgatc cgctgggcgc
     8821 acgaacgggc cctggccagc gtggtgagca acgggatctg gccgaccagc cccatgccga
     8881 gcgcgacgta cccgagcgcg gcgagcacgt caccgacgct cagcctgccg ttcagcacgc
     8941 cgaacccggc ggcgatcagc accgcgacct cgaccgcggg cagcaggagc gcggcacgcc
     9001 agatcatccg cgcctgggtc tgccacatac cggaaccggc cttgccgagt tcgggcagcg
     9061 ggcgcagcac ccggcgcgtc tcccgatcgg ccgtgccgga ggcggcgatg gtccgcagcc
     9121 cgcgcacggc gtcgagcagg cgtgcggaga tctcgccgga cacgcgctgg taggtcagca
     9181 cgtcgtcggc ggtgttgcgc aggtgggagc gggccagcca gagtgcgatc ggcacgctgc
     9241 cgaggaaaac cagggcgagc cgccagtcga gcaccgccag cagcacgatg gcgccgacgg
     9301 acaggcaggc cgccgaaccc agctgcacca ggatggaggc gaccgaaccg gcgctcacgc
     9361 agtcgccggt gagccggctg atcgcgtcgc cgtcggcgaa ccgggagcgg gtgccgaggc
     9421 cgagcaggtg ccgggtgagc cgtcgccgca gtgccgcggt ggccgtgctg gtcacggcga
     9481 cggtgagcag tccgccgagc acgtcggcgg tgatgtcgag tgcgccgagc ccgagcagca
     9541 gcagcacctg gggccagctg cgctgaccgg agatcgcggc gtccaccgcg ccggcgagcg
     9601 cgccgggcag caggagaccc gcggtggtgg cggtgagcgc ggtcagcagc accaggccca
     9661 gccgggcgcg gtccccaccg gccacctcgg ccagcaaccg gtcaccccgc atcggcgtgt
     9721 cccaccttcc gaacgaactg tcgcgcaccg gccccctcgg ggttgaatag gaacgcggga
     9781 gcggcgcact tggcctgtgc cgctcccgcg tctcgcctag ccgcgactag ctcagtggca
     9841 ggtcagcagg gaaacggtgc tgttgttgca ggaggccagc aggctcaggt tcgagccgcc
     9901 gccaccgcca ccgctgccgc cgccgaactg ggggccctcg gtgtcttcca tggcctgcag
     9961 gtccagaacg agctccatgg gtgttccttt cgtcgggtgt tcatccaccg gccgtgctcg
    10021 accggggtcc gggggacagg aacggcagca ctgcgccgtg cccgtcgagg gtggcggcca
    10081 gggcgaggag caccccggca ccgccggtgt agagatccat cgacaaccgc agcagctggt
    10141 tgccggggaa ggcgagcccg tcccggtacg gcagcgcgta ccaggcgaac cgcgaaaggt
    10201 gcaggtccac cgcggccagc gcgaccgggt caccggtgcg ccgcgcctcg gcggaaagcg
    10261 tggccatcag cccggcgcgg ccgagcatca ggccggggtg gatgacgaac tcaccacggc
    10321 aggcgtccag cagccgcggc agcttctcca ggcagtccgc gtccggccgg tgcgcggcca
    10381 gctcctcggc ggccagcgcc accccggcgc tgcccatgcc gacgtacggc agggtccggg
    10441 attcgccgtc gcgcacctgc aacgagccgt cgtcggcggg cacgcactcc tcgagatcgc
    10501 gttcgacggc cttcgccgcg aggtccagcc atgcctggtc gccggtggcc tcgaacagcc
    10561 gcacgaacag cagggccggc cccgaccagc cgctcatcag cccggccctg gcgaacttca
    10621 gcggtccggc gtcggtggcc agcgcgttgc ccagccgctc gccgatggtg accgcggtcc
    10681 gctcgaagtc ggcgtcccgc cgggtcccgg cgaagtgcag gtagttcagg ccgatcccgg
    10741 ccagcccgcc ttcgagattg tggtcggtgg tgatctcgac caggtgccgc gaagccgcga
    10801 tcagctcgtc ggcccggtcg tggtggccga agttctccag cacgtaggcg atgccgtggg
    10861 tgccgtcgta gaaaccgggg cggctgggcg gggtccggcg gaccgcgtcg agcagccact
    10921 gctcgtgctc gggatagcgg ccctcaccgg cggcgtgcaa cgcgtgcagc acaccggcgg
    10981 cgccgtaacc gaagccgagc ccgccgacct cgaactgctg gatgtcgccg gggaagagcc
    11041 ggtcctgccg atcgggcgtg gcgctggcga ggatcgccgt cgcgatcgac ttgcgcacca
    11101 ccgcccaatc cggcttgggc tcgtcgagct gggtgacggc cggacgcacc tcggcgtccc
    11161 cacgcgggga gagcacgtcg aggatgcgcc ggccataccc ctcgggcaaa gggaaccggc
    11221 gctcggcgaa gtccacgagc gaggcgagtt tggccggcgc cagttcgagg atcgtgttga
    11281 gcggcaggaa caaccacagc cgcagagccg ccagcgcgta ctcgtcgatc tcgaaaccgg
    11341 tgcgatcccg ctgcgcgcgg aagccgggcg cgccgagcgc cggcttggtc tcctcttcga
    11401 ttcccgccgc gagttcgaaa tcgatcaggg agaccgtgtc gtcgttgttg tcgtccacca
    11461 ggatgttcag cgcgtgcagg tcaccgaaga ccaccccgcg ctcgtgcacc gcggcgacca
    11521 gccgctcgac ccggccgatc agcgccaggg cgcgctcggt gtactcggcg acgtcctgtt
    11581 cggtggcgtc ccgcctggtc agcgggtagt tgcgggcgag ccaggcgccg accggcttgc
    11641 ccggcacgaa ctgcatcgcc aggaagtggt gctcccacac ctggaagcgg tcgtagacct
    11701 cgggaatgcc gggaatgccc gccagccgct cgaggatccg gtgctcgcgt tcgagcctgg
    11761 ccaccgcgtc caccaggtcg cggtccaggc cggcgtgcgg ccgggcctcc ttgagcacca
    11821 cttcgcggtc gtcggccagc cggttggcca ggtagacccc gccgccgttg gagaagtgca
    11881 gcgatttggt caccttgtac gggaactgcg ccgggtcgcc gcccttgcgg gccgccaggt
    11941 gcggctcgag gcattcgggc aactcgaccc agtcgggcac gtggaaactc ggcccgcgct
    12001 tgtccggcac cagcgtgccg tccggcttgc tgatggccag cacccgcgtg ccgtcggctt
    12061 ccacccactg ctcggcaaaa ccaccgtaac gggcgtagag tggcccttcg ccgtaacgca
    12121 ggtcgctgag aatgtacgga cccacctcgc cctgcagctc ggcggaaagg tcgctcagca
    12181 cccgctggag gctctcttca tccggcggat aaattgttat cagcttaccg ctgccatccc
    12241 gtggcgcata tttcgaattc cgcgccagca ggatcgaccg gctgcgcagg tgcttgaagg
    12301 cgatgcgctg ctcgacgcag tacgcggcca ccgcgagcag gacccgctcg gcgttcgcca
    12361 taccggccga aacgtggatc ttccagccct gagcaggcaa aaccgcgtcc gccggggaca
    12421 gcgagcgcca gatcccgcgc tcgccggacc gccactcgga gcccagcgac ggcagcacgg
    12481 cggcgaaatc gtccttcgcc tggccgtcgt cgcgctgttc gtcgaagaac agcggatccg
    12541 cgaagcagaa tgcttcgtat cggaggtcca tccagcagag acctttctca aggggagatt
    12601 tcccgccgcc gctcggcgtt ttgggatgcc gcaatatttc cgcacgccgg ggggccggcg
    12661 gccaatccgc catttcggcg tttcggccga gccgaccgga ccatcgacac tgagcttact
    12721 gacgagtaag tcaacagtgg gtcaacatca ccgaaagttg gttcacccgg tcggtgcgta
    12781 acgagcaagg tcatcgacaa aggtgctggt aggaccgctt aaggaatgtg cactaattca
    12841 ttctaacgag aacgctcgtt ttggtgatcg gttttccgct cgtatcgtac gatcgccgta
    12901 gccggggtca atccccggtg gcggcagaag tacccacagg cacgaaacgg cggaagagcg
    12961 ggcgccagat ccggccccgc agcagggcac tgcgctcctc cagttcgacc cggccgcgcc
    13021 ggtgcgcctt ccagcccgcg gatcccccgt cgtagctggt cacgtattcg atggcgcaga
    13081 cgtggcgcac gctcttgtag ccgtagtgcg ccggggcgac cagccgcagc ggagcaccgg
    13141 cgtcggcgtc gagcggttgc ccggcaaggg agtcggcgag cagcacatcc gccgccagcg
    13201 cgtcgtcgag cgcgaggcag ctgcgaaacc cgtccagtcc ggcgaaaacc acccagcggc
    13261 acttcgggtg cggttcgacg cgccggcgga gcacttcgtg cacctcgcgg aacgggacgc
    13321 cgccccagcg cagcgagaga gcgctccaag tggtgacgca gtgcagatcg ctgatctgct
    13381 cccgccccgg cccgccgagc agttcggcca gttcgagctg cacgggacgc cggaccacgc
    13441 cggtcaccgt gaccaccggg cgcgcgggca cctccggccg cacgcggtgg aactcgggca
    13501 ggccgaaccg ctgacgtgcg gcaggccact gacctggggg caaagcgggc atgacggcac
    13561 ctccgtttct agagactact ctccaatact agcggtcagg gctcaaccct gagttctccc
    13621 ggagatcgct cgcggaccat ggccgcggcg ccgcgcacct gtcagcattt ccttacacgt
    13681 aagagggcac gcgaatagag caggtggatg gccgtcgtga tcgaggtggt ggttcctggc
    13741 ggtaccgcgc cggcatcggc gtactggacc gtacttcgat gtcggcgcgg tgccgccagg
    13801 ggccgcctcg gcgcgacggg cgccgccatg ccctattcgc gccccctcta aggggatgag
    13861 ctcgatgccc gagaccgggg acgcgctcct gcgcacgctg accgcgctgg cgaaccccca
    13921 ccggctgcgc gtgatcggcg cactggccgg tggccgccag tacgtcagca agctggccag
    13981 ggaactcggc atcagcagac cgctgctgca catgcacctc cagcggctgg aagcggcggg
    14041 gcttgtcgtg ggcacgctgg aaaccggtga ggacggaaaa ctcatgaagt acttcgaggc
    14101 aacggaattc gcgctttcgc tcagtcccgc gacgatcgcc gcggcggtgc cgaccctgtc
    14161 cgagcggccg ggggaggatc gatgacctgg caggaaacca cgatcacgat ggtctccatc
    14221 atcttcggca tggcgctggt catcgtggtg gtgctccagc tgagcaagat catcagcacc
    14281 gtggcgtcgg cccggcgcga gcgggtgctg cgcgaactgg ccgtcgagct gcgtgccggg
    14341 caggaccacc tcagcgccga agtcgccgag atccgccgca tcgtcgagga aacggaacgg
    14401 agggtgcgcg aagtcgacta ctagggattt ttccgtgcag tgaaggggat cgccgagcgg
    14461 gaactcggcg accccggacg aagacaccgc acgcgcgtcc gctgaccacg atccgcgcgt
    14521 gtgttaccga gagaggcacg catgtcctcc ttgtcgatgc tacccgcgcg cgccggggtc
    14581 tacaccacgt ccatcgcgca caccgccgaa cagctccgcg ccgcccagcg gctgcggcac
    14641 cgggttttcg ccggtgagct gggcgcccgg ctcgacggcg aactcgacgc cgacgagttc
    14701 gaccggttct gcgaccacct gatcgtcgag cacgaaccca ccggcgaggt ggtcggcacc
    14761 taccggctgc tgccgcccgg ccgcagcgat ttcctgtact cgcagggtga attcgaactc
    14821 ggcgcgctgg acccgttgcg ctcgtcgctg gtggagctcg gccgttcctg cgtgcacccg
    14881 gaccaccggg gtggcgcggt gatcggtctg atgtggacag cggtcgcgcg gtacgcgcac
    14941 ctgtccggca accggtactt ggccggctgt gcctcggtcc ccctcggcga cggtggcatg
    15001 gcggcggcgt cgacactggc cctgtccgag aagcacgccg gtccgtacga agtgacgccg
    15061 catctgccgt ggattccttc ggtggcaggg cgtccgagtt atgcacaggt gccgccgctg
    15121 ctgcgtgggt atctccggct gggcgcgtgg atctgtggaa aacccgcgca cgacccggat
    15181 ttcgacgtcg ccgacttctt catcctgctg ccgctggacc ggatcgacga tcgttacctc
    15241 cgttacttcc tcggggcggc gcaatgatcc acagcccgtg cacacccttg tgcataactg
    15301 agccatggcc accggtcgac tcggcgacag ccgcccgccg ggcttcggca ctgctttccg
    15361 cttgcacgag cggaagtctg cgcgagcggg cgtggcgggc gttgcgcgca ctggacgtcg
    15421 acgtcgagca ttccgcttac acgccaagtg aacccggcac gctggtggtg gcgaaccaca
    15481 tctcgtggct ggacatcccg gtgatgctgg cgctggattc cgcggtgttc cttgccaagc
    15541 gcgaagtggc acggtggccg ttcgtcggtg ggctggcgat gcggtcgggc acgttgttca
    15601 tcgatcggca cagttatcgc gggttgccgc ggaccgtggc ggaactggct cgcaccttgc
    15661 gttccgggcg ttcggtggtg gtctttccgg aggccaccac gtgctgcggg gtgcactcgg
    15721 cgccgttccg ccgggcggct ttccaggccg cactggacgc gggcgcgccg atccagccgg
    15781 tgcggatttc ctaccaccag ggcgatgcac cgagcaccgt gcccgcgttc ctcggcgacg
    15841 acactctgct gacctcggtg cggcgagtgc tgcgcgcccg cgagctgcgg gtgcgcgtca
    15901 gctcgagtcc gctgttggaa cccttcggtg accggcgccg cctcgccgct ctggcccagc
    15961 acccatgctt gatctcctga actcgttcgc cgagctggtg tccggcgcgc tgggttcgcc
    16021 gtggctgtgg gtggtggtgt tcttcgtgtc cgctttggac gctctgctgc cgttcatgcc
    16081 cagtgagacc acggtgatca ccgtcgcggt gctgctgggg caggcggccg ggagcctggt
    16141 ggcgctggcc gtgctggcgg cggccggggc gctggccggg gactgcctga gccacgccat
    16201 cggccgccgg gcgggcccgc gggcgctggc gcgcctgcaa cgcggcgagc gcgggcagcg
    16261 gcggtacgag tgggtgcggg acaagctggc caggcacggt cccacgctga tcatcgccgg
    16321 gcggtacctg ccgggtggcc gggtcgcggt cggcctggcc accggcagcc tgcgctatcc
    16381 cctgcggcgg ttcgtcgcac tggacgcgct cggtgcctcg atctgggcgg tgtacagcgt
    16441 gctggtcggc tacctgggcg gcgcgagctt cgccggcaac ccggcgatgg gcctgctggt
    16501 cgcgttcggc atcggcctgg ccacggtcgg cctggtcgaa ctcggccgcc gtcactacgc
    16561 acggcgacga gatcgggtgg atcaggcgtc accgacgtag atggctttgt ccgcgccgaa
    16621 ggtgggctgg aaggcgattt gcatttcgcc gggttgcggg ccgacggcgt aggcgaccga
    16681 ataggtgaag gttttcccgg gcagcacggt cgccgattcc aggccgccgc cgcattcacc
    16741 gccgaagtcg tggatctggt ccgctttggc accgccgaat tgggcgtcgc cgccgaggga
    16801 gagcagggtg gcgtcgaagg gttcgctggt tccgttggtc accgtgacgg tgatcttgac
    16861 cgcgcgctcg atgttcggcg gcgcggcggt gtcgctcggc ttgcacgcgg ccggggcggc
    16921 gacgtccacc gcgagaccgc tctcccaggt gtaccgcttt ccccaggtcg gagcgtccgc
    16981 gggcaccccg ccctcacctc gcccggcgtc ggcgacgcgg ccctgatcgg tggtgccgtt
    17041 gaggatctcg tccagcttct ccaccgccgc ctgctgggcg atcacggtga acacgatgcc
    17101 ggccacgcac aacgcgaccc cgatcccggc gaggatcttc ttgctgccga aaagcgcgat
    17161 cgcaccgagg atgaacccca ctccggcgac caccgcggtc aggttgttca ggaagatgat
    17221 cggcgaaccg agcacgccga caattccgag aatgagcgaa ctccaggcga gcgcggcgaa
    17281 tttcgccggt ttggcctggg gcatcatcgg cgggggcaga gtgggctgag cggtcatggc
    17341 ggcggctccg gaaaagtgcg cgggcaattg tccaccaatt cgccgcccga ctgcgttccg
    17401 ttacggccgc ccccggcgcg tgaccggaac gtcatccagt tacccctgat caggtgacgt
    17461 cagtcgccga ggagccaggt caggaaagtg cggaactccg ccagctgctc agccgggttg
    17521 aagccctctt cgtcggcggc caggaaggcg gcgtccgcga cgcgctggat ccacacggcc
    17581 acccgctccg gcgcgaaggc caggcgcgcg gaatccagcc gccccagcag ttcggtgagg
    17641 gtggcccgga tacgcaactc gttcgcctcg atcatctcgg cgaactcctg gtcctggttg
    17701 atctgcagca acgccgccgc catcaggccg ggtatcagcg gatcggcgag atcggccatc
    17761 aggtgctctg ccacctgccg caccccggtc gccgggtcgt cggccgccag cgcgcgctcg
    17821 cacacctcgg cgtcgcgcac ctggtcgtcg cggaacaacg cgtggaagat ctcccgcttg
    17881 gtcgggaagt agtggaacag cgtgcccgag ccgatgcccg cgcggcggca gatgtccgcg
    17941 gtggacgtgc cgtcgacccc ggccgcggcg aactcctggg cggcggccgc caggatctcg
    18001 gcgcgcctgc gggcgtgctg ttcgggattg acggtacgca tcaagatcca ggataaccca
    18061 ttaccagagc gggtactctg ctaatcatgg acgtgcgcgg catttcgtac accgtggccg
    18121 acaccgaccc ggccgaagac ctgcggacga tccgcgagga actgcactgc accacggtcc
    18181 tgctcgccgg taccgacgcc gcgaagcagc tcagagcggc ggagaaagct ctcgcgctcg
    18241 gcctcgacgt ctggatcgag ccgcagatcg gcgaccgccc cttcgacgac gtgctggcct
    18301 ggatcgccga ggcggccgcg ggcgccgagg aactccgcgc ccgctatccg ggccgggtca
    18361 ccctggtcgt cggctgcgag tactcgctcc ggctctccgg catgatcccc ggtccgcgcg
    18421 agttcatccg gctccaggtg ctgatccgct ggccccgcaa gtggagagcg cgcagctccg
    18481 ttgagggtgg tggtgggctg gcgggcgggc tattcgaccg ccggatcacg cgggtgctca
    18541 accgccgcct cgcccgttcg gtggccgtcg cgcgcggcgc cttccacggc ccgatcacct
    18601 acgcggccgg ctactgggag caggtcgact ggtcgccgtt cgacctggtc ggcgtcaatc
    18661 tctaccggat gggcgacaac cgcgaagcct acgaggaccg gctgcgcgaa ctcgtccgga
    18721 gcacggacaa accggtggtc atcaccgagt tcggctgcgg cgcgttcacc ggcgccgacc
    18781 ggcgcggtcc cgcgtcgttc ctgatcgtca actggttcac cagcccgccg cgcatccgcg
    18841 acggccacgt gcgcgacgag cgaacacagg cggcctacct cggcgaactc atcgagctgt
    18901 acgaacgcga ggacgtgcac ggcgcctttg tcttcaccta ctggatgccg gacttcccgc
    18961 accaccccga cccggcgctg gacctcgaca tggccggctt cggcgtggtg aaggtgaccg
    19021 ccgacggcaa gcgcgtgccc aaggaagcct tcaccgaagt ggcacatcgc tattcggcca
    19081 caacggcctc ctgaacgcga tcacaaaagt acggtctggc cgtgcgtgaa ctcgctgtcg
    19141 acttcgggac ctccaacacg gtcgccgcgt tgcgggccaa cggcggtccg tcccgcctgc
    19201 tgctgttcga cggctggccg gtgcttccgt ccgcggtgct gcgcgggcgc gacggcggtc
    19261 tggtcgtcgg ccgggaggcg ctgcgtggcg cgcggctgga cccggcgcgc ttcgaaccgc
    19321 accccaagga acgcatcgac gagggcgagg tcctgctcgg tgacgccgcc gtgccggtgg
    19381 tctcgctgat cgcggcggtg ctgcgccggg tcgccgcgga ggcgcccgcg cccgatcgtg
    19441 tcgtgctcac ccaccccgcc gactggtaca gctcacgccg cgcggtgctg ctggcggcgg
    19501 cgcgcgaagc gggatggcaa ggggaagtcc agctcgtcgc cgaaccggtc gccgccgcct
    19561 cgcaggccgc cgacgtgccg cccgggcagg cggtcgcggt gttcgacatg ggcggcggca
    19621 ccaccgacgt cgcggtcctg cggcgcacga gcaccggctg ggacgtgctc gccgaggcgg
    19681 gcctgccgga cttcggcggc cgcgacctcg accagttgct gctggaccac ctcggcgtcg
    19741 aagtggaccc gacggccgac gcggcggggc ggcgcgcggc ccgcgtgctc gccgaggacg
    19801 tgcgggcggg caaggaagcg ctgtcgcagt atccgcagac cgacatcccg ctccccgcgc
    19861 cgcgacccga cgcgcacctg acccggcagg agctggaaac cctggtcgaa gcggcactgc
    19921 gacgggcggt cgacctgctc gcggaaaccg tcggcaccac ctcgctcacc gccgtccacc
    19981 tggtcggcgg cgccacgcgc atgccgctgg tggcccggct gatcagcgaa cggcttggcc
    20041 tggtgccgac gatcgtcgaa tcaccggaaa ccagcgtcgc gctgggcgca ctgggcccgc
    20101 cgccacgtcc acaaaggaca ccatttcccc cgccaccgct gccccggtcc acgccgatgc
    20161 ccccgcctcc gccggaggag cggaagaaac cgccggtcgc cgccatcacc acggcgatcg
    20221 tggtgaccct gctggccgcc ggtggcgtga tcgcggccgc gctgctgcgc ccggacaccg
    20281 tcggcaccgc ggtggtggga ccgacgccgt ccgcgccccc ggacaacccg gccttccgcg
    20341 gggacgagcc actgatcgcg ttcgccggac cggccgccgg gaaggccgac gagtgcgtga
    20401 acgtcatggg caccgccagc cagggcgacc agtactcggc gcgaaaccac gtgcgctgcc
    20461 ggttcgagat cgacggcatc gcctacttcg cgaactacct gtcggcggac ggcccgcaga
    20521 cctgcggcca gctcaacgag gagttcctcg aactgcccgg cgcgcagtgg ctgagcgaag
    20581 atccctggac gggtggcgac ctgcgcggga agtcgcacga cgtcgccgcg accagcggga
    20641 acaacgtgct ctggtacacc gacacgaaca cgctgtgcgc cttcttcggc gcgagcaccg
    20701 accagaaccc gccgatgtcc gaagtccacc aggcctggga aacagtcgtg ggtgcgtagg
    20761 aaagccctac gcacccacga aaaccgcctg agggatcaga ccgcgttgct ggtctgcatg
    20821 ccgatgtcgg agttgatcgc ggcggtgatg atccggtccc gctggtcact ggtcagcacg
    20881 ccgtagccga cgagttcctt ggtcaccgcc ttgacgtggc gcacgaactt ggtgtgcgtc
    20941 gcgtactcgg cgttctcggc gatgacgtcg ttgatcgtgc agccgttgcc gatgtccacg
    21001 ttcttcacct ggctgtcgat gccgccgatg atcaccgtcg agcgcaggtc cgaatccggg
    21061 caaacgtcct gccccggccc ggaaccgccc ttgaccacgg agaacgtgcc ggtgcgctcg
    21121 tcggcgacgt tgccttcctt gtccgacgcc cggtacttga ccgtgtgcgt gccgaccgcg
    21181 gtcacctcga ccggggccga gtaggccgcc caggccgcgc cgttcagctg gtactcgatc
    21241 ttgtccacgc cggagccggt gtcggtggcg gtcagcgtca ccgtcgcctt gtccacgtag
    21301 gcccagttcg agttctgcgt gccggtcacc gtcatcgagg tcttgggcgg ctcgacgtca
    21361 ccactgccct cgacgatggt gaacgcggac gaaccctcgg cggaagcgtt gcccgccttg
    21421 tccgtggcgc ggaacttcac cgtgtgcgca ccgagcgcgg tcaccggaac cggtgcggtg
    21481 taagcggtcc acgccccgcc gtcgagctgg tactcgacct tgtccacgcc cgaagcctcg
    21541 tcggtcgcgt tcagccggat cgacgccgag ccgacgtagg caccgtcgga gttctgcgtg
    21601 ccgtcgatga ccgcggccac caccggcggg gtggtgtctt cgccaccgcc ctcctcgacc
    21661 acggtgaagt gcgacatgcc ctcctgcgag gtgttgcccg ccttgtcggt cgcgcggtgg
    21721 tgcaacatgt gcgcgcccgg cgtcgagacc acaaccggtg cggtgtaagc ggtccacgca
    21781 ccaccgtcga gctggtactc gaccttgtcg acgcccgaac cctcatccgt ggcggtcagc
    21841 tcgaccgaag ccgagccgac gtagttgccg tccgggtcct gcgtgccggt caccttcgcg
    21901 gtgaccaccg gcggcgtggt gtccgcgcca ccgccctcga cgatggtgaa cgacgccatg
    21961 ccctcctggg aggcgttgcc cgccttgtcc gtggcgcggt agtggaccat gtgcgcgccg
    22021 accgcggtca cctggaccgg tgcggtgtaa gcggtccacg caccaccgtc gagctggtac
    22081 tcgaccttgt cgacgccgga gttgtcgtcg gtggcggtca gttcgaccgc ggcggaaccg
    22141 acgtagttgc cgtccgagtt ctgcgtgccg gtcaccttcg cggtgaccac cggcggcgtg
    22201 gtgtcctccc cgccaccgcc ttcggtgacc acgaactcgc cctgcatcga gctgtggccc
    22261 ggcagcgcgc agaagtagcg gtacttgccc ggcgtcaggg tgacagtcag ctcgtggcgg
    22321 cccttgttgg cgtcggtcgg gctggccgtg atgttcacct gcgcgtcgtg gttgtagcca
    22381 ggtgtggagt tgtcgaaggt cagcgtgtgg agcatgccgg tgtcgttccc ggtcgccacg
    22441 ctgttctcga agacgatggt ggtctcaccg gccaccgcgg tggtgggggc ggaggtgtac
    22501 ttggtgacgt tctcgtccga agtccaggtc agcgtttggg ccgcggcggc cactggcgac
    22561 gacgccgacg c
//
