LOCUS       NZ_CP045480            21098 bp    DNA     circular CON 15-AUG-2024
DEFINITION  Amycolatopsis sp. YIM 10 chromosome, complete genome.
ACCESSION   NZ_CP045480
VERSION     NZ_CP045480.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. YIM 10
  ORGANISM  Amycolatopsis sp. YIM 10
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Complete genome sequence of Amycolatopsis sp. YIM 10, isolated from
            a rare earth mine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2019) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009429145.1-RS_2024_08_15
            Annotation Date                   :: 08/15/2024 04:03:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,775
            CDSs (total)                      :: 9,711
            Genes (coding)                    :: 9,634
            CDSs (with protein)               :: 9,634
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 22 of 77
            Pseudo Genes (incomplete)         :: 65 of 77
            Pseudo Genes (internal stop)      :: 1 of 77
            Pseudo Genes (multiple problems)  :: 11 of 77
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7962987
            Orig. end                         :: 7984085
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045480.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="31"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21098
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21098
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11098](+)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11098
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            complement(555..890)
                     /locus_tag="YIM_RS37615"
                     /old_locus_tag="YIM_37820"
     CDS             complement(555..890)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227424.1"
                     /locus_tag="YIM_RS37615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37820"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_153037494.1"
                     /transl_table=11
                     /translation="MVDEFPVPPIGEVALGTVLSALADPHRRQVVLALLSGGGAERACA
                     SFALPKAKSTRTHHWRVLRDAGLVRQRNAGNGTFVRLRDEFEGRFPGLLALLADLDHAP
                     SASTVDE"
     gene            963..1583
                     /locus_tag="YIM_RS37620"
                     /old_locus_tag="YIM_37825"
     CDS             963..1583
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013227425.1"
                     /locus_tag="YIM_RS37620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37825"
                     /product="HAD family hydrolase"
                     /protein_id="WP_153037495.1"
                     /sec_met_domain="HAD_2 (E-value: 5.8e-06, bitscore: 25.6,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLCVFDINETLLDLAPLDDVFGSAEARRAWFAQVIHTALTITATG
                     GYRDFAAIAGAAADEDVRPKVGPVLRGLPAHPDVPGGLTRLREAGFTLVALGNSPLATI
                     EAQMSNSGLRDHFTAVFSAEQAGALKPAAAPYRTVLGAYPGQDAIMIAAHGWDIAGAAA
                     AGLRTAFVERPGQRQLPGGPTADFSAPDIEVLATKLIEAGTAR"
     gene            complement(1590..2411)
                     /locus_tag="YIM_RS37625"
                     /old_locus_tag="YIM_37830"
     CDS             complement(1590..2411)
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023144.4"
                     /locus_tag="YIM_RS37625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37830"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_194239878.1"
                     /transl_table=11
                     /translation="MADAVSGTLAQARAAVREVVPRLFELVRSIPDAGSASVGAWTVGE
                     VAAHLSHVFRFDTDAIAGKPVPDAVVTSAGMAEVNAKMLTRDEERDPAALADRLGALAV
                     EFDDVVSCSRTATTGWLQGVRVPPSVVACHLLEECLMHGHDIAEAVGRPWAISRHHAVL
                     AVEGGVLPLIEALPPTAFVDQEKAGAFRGRFELRLRGGGRTTMVFDRGSLTLDPGSARA
                     VDAHIRADPSALMLVFIGRRGLWKPLVGGQLAAWGPRPWKLARLLTAISPP"
     gene            2581..3654
                     /locus_tag="YIM_RS37630"
                     /old_locus_tag="YIM_37835"
     CDS             2581..3654
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017885.4"
                     /locus_tag="YIM_RS37630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37835"
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="WP_153034910.1"
                     /transl_table=11
                     /translation="MPISPSRLTLARKLRAMTLADLSSLTDLSPQTINRCELGHQEPTA
                     DSVNRLADALKLPPAFFHRPDVEPLPTATASLRSPSKTSAFRRDAVLAAALIASEIAAW
                     IGARFRLPRANLPTAPANPSAEDIEAMARRIRNEWGLGQRPIPNLIHLLESRGVRIFSL
                     VQEVRDVDAFSVFLRGEPFIFIDTGKTAERQRFDAAHELGHLVLHQGPGRIDGREAERQ
                     ADRFAAALLMPRGDVLARNLHQADAARLRQASRRWGVSPMALAHRLSELDIITRWRYRT
                     LCPELAESGSHLTAETSQVLEKVFAHLRRSERGVRAIADDLELTPEEFNRHVFGLAAVH
                     LHAVAPAGVAQSSRCAG"
     misc_feature    2610..2623
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.82"
                     /tool="antismash"
     gene            3741..4508
                     /locus_tag="YIM_RS37635"
                     /old_locus_tag="YIM_37840"
     CDS             3741..4508
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007030107.1"
                     /locus_tag="YIM_RS37635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37840"
                     /product="metalloregulator ArsR/SmtB family transcription
                     factor"
                     /protein_id="WP_153034911.1"
                     /transl_table=11
                     /translation="MPTTETAEPPPFVRLAGDPLRWQLLRQLAHGDRRVRELVEAVGQP
                     QNLVSYHLRKLRAAELVTARRSSFDGRDTYYHLDLSRCADALAETGIALHPGLAPGRVN
                     RTRSTARLKVLFVCTGNSGRSPMAAALLRHRAGPSVEVFSAGSAPKPLHSEAVRALAGY
                     RVPLTHEPTHVDSLRRRRFHWVITLCDRAREVCPEFPGHPRVLHWSLPDPAKETDDAGE
                     TLPAFRRLAGELDRRIGFLLPRFGMSAEAESRI"
     gene            4528..4911
                     /locus_tag="YIM_RS37640"
                     /old_locus_tag="YIM_37845"
     CDS             4528..4911
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016333340.1"
                     /locus_tag="YIM_RS37640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37845"
                     /product="VOC family protein"
                     /protein_id="WP_153034912.1"
                     /transl_table=11
                     /translation="MTSDLVSVRYLVDEVEAAVEFYTEHLGFTINTNAIPAFADVVRGN
                     LRLLLSGPASSAGRPMPDGTKPGPGGWNRIHLIVDDIDAEVARLRAAGIRFRSDVVSGP
                     GGRQIVFDDPAGNPVELFQPAAR"
     misc_feature    complement(5150..5163)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 20.85"
                     /tool="antismash"
     gene            5255..5647
                     /locus_tag="YIM_RS37645"
                     /old_locus_tag="YIM_37850"
     CDS             5255..5647
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS37645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_37850"
                     /product="hypothetical protein"
                     /protein_id="WP_153034913.1"
                     /transl_table=11
                     /translation="MLGSTKFRLLLLAGLLALQFLAPALAPGTPSVALNGITDATDATA
                     TAAERSEPEHAVCDSPDPTSPNGLPRTRDRYRAPADLSPQPVARPASTCADVAARPPTA
                     VVALARPPHLGASAADSAAVLQVFRR"
     gene            5782..6372
                     /locus_tag="YIM_RS37650"
                     /old_locus_tag="YIM_37855"
     CDS             5782..6372
                     /GO_function="GO:0004089 - carbonate dehydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950857.1"
                     /locus_tag="YIM_RS37650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37855"
                     /product="carbonic anhydrase"
                     /protein_id="WP_153034914.1"
                     /transl_table=11
                     /translation="MQSLIEHARSFRRQCEDRAEQFARLADGQSPQVLFVTCSDSRVVP
                     ALITGARPGELFELRTAGNIVPPYAAGRPSGEVATIEYAVEVLGVTDIVVCGHSHCGAV
                     GALVRGDDLTAVPAVHGWLSHATPRPEGTVEDPAVADAVQNHVLTQVLRLRSYPGIDRR
                     LSAGEVRLHGWFYEVHTGSVLAHDSDTDTFQAL"
     gene            6381..7853
                     /locus_tag="YIM_RS37655"
                     /old_locus_tag="YIM_37860"
     CDS             6381..7853
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015103 - inorganic anion transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011873547.1"
                     /locus_tag="YIM_RS37655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37860"
                     /product="SulP family inorganic anion transporter"
                     /protein_id="WP_194239879.1"
                     /transl_table=11
                     /translation="MDLRTKFPHLRQDFTASLVVFLVALPLCVGVAVASGVPAELGLIT
                     GIVGGIVTGLMRGSSLQVSGPAAGLTVLVFEAVRQFGLPALGVIVLAAGLLQLAMGALK
                     LGRWFRAISVSVVEGMLAGIGLVLIAGQLYTAAGLTAPASGIGKLAGLPGAVAEVVGNP
                     TALASIALGAGTIAVLVLWKRMPKRVQAVPGPLAAVGLASVVSLVFSLPVATVEVQGLL
                     GAIQLPELASFGELANLSLIGTILAFTLIASAESLFSAAAVDRLHNGPRTEYDKELMAQ
                     GTGNTVCGVLGALPMTAVIVRSSANVQAGAKTKASRVLHGVWLLLFAALLPGTLALIPL
                     PALAGLLVHAGWKLIPLRSIAALWREHRGEALILVVTAVSIVAVNMFEGVLIGLALSVA
                     KTAWEASHLKLEVIDKGAGPIQAYLSGNATFLRLPKILDDLEALPRDRPIELDLSGLHH
                     LDHACRTALETWSAQHSAGPDRVKVTASATSG"
     gene            complement(7930..8406)
                     /locus_tag="YIM_RS37660"
                     /old_locus_tag="YIM_37865"
     CDS             complement(7930..8406)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS37660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_37865"
                     /product="hypothetical protein"
                     /protein_id="WP_153034916.1"
                     /transl_table=11
                     /translation="MNRNRMISVASAAAVFLLIPVAAAHTASAVEPVEPVEAVCAFQQL
                     ADYPHVTRGDASVHGWWDWVKPVPADCVKASGNKADVTVYLQTSLDGKEWTTRSEGEKR
                     VYAGGGSVARANARYTCRNTAKTKWRAVVDVDVVGIADLPNKTEYPHRDLDCGF"
     gene            8510..8749
                     /locus_tag="YIM_RS37665"
                     /old_locus_tag="YIM_37870"
     CDS             8510..8749
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS37665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_37870"
                     /product="hypothetical protein"
                     /protein_id="WP_153034917.1"
                     /transl_table=11
                     /translation="MPEFDPSSRTLLVDGETFEVHHDPDQPGVHQLTWTTGPNAGYGFS
                     IARSDHAEIGDAELIAQAREFLAGIDPATGFLSE"
     gene            8988..9776
                     /locus_tag="YIM_RS37670"
                     /old_locus_tag="YIM_37875"
     CDS             8988..9776
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1136: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010223775.1"
                     /locus_tag="YIM_RS37670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37875"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_153037496.1"
                     /transl_table=11
                     /translation="MLELGQVDRRADTPPYRQIAAMLIEAIDDGRLEPGQKLPSEAALI
                     EHFGVARMTVRQATQELRRQGLVVAEHGRGVFVRSPSSTLPVRRVASDRFARKHRQAGK
                     AAFLADAEKLGYQPSVDRIQVRRETAPPMVAERLRVDPDDEVVVRDRRYLANGRPIEMA
                     TSYVPTELAEGTQILEINPGPGGIYARLEERGHKLASFTEEVTARMPNSREVRELGLPE
                     GAPVLTVIRTAFDTDGAVVEVCDIVKAASSYVLEYDFPAK"
     aSDomain        10001..10267
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_YIM_RS37675_Pantocin_Microcin_RRE.1"
                     /evalue="1.00E-17"
                     /identifier="RREFam017.1"
                     /label="YIM_RS37675"
                     /locus_tag="YIM_RS37675"
                     /protein_end="89"
                     /protein_start="0"
                     /score="55.0"
                     /tool="antismash"
                     /translation="MRLRIKLEHRPVRFGDGVIQIGGELFGIAGKLHDPDGAVWALLGL
                     LDGSRTVDQVVTDLIHRFPEHSVQMVLDGIETLAKAGYLEDVDE"
     gene            10001..11098
                     /locus_tag="YIM_RS37675"
                     /old_locus_tag="YIM_37880"
     CDS             10001..11098
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020635656.1"
                     /locus_tag="YIM_RS37675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37880"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_153034918.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 3.6e-15,
                     bitscore: 55.0, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 1.1e-44, bitscore: 151.8,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLRIKLEHRPVRFGDGVIQIGGELFGIAGKLHDPDGAVWALLGL
                     LDGSRTVDQVVTDLIHRFPEHSVQMVLDGIETLAKAGYLEDVDEPECAALSTWQRERYG
                     RGRALNQWVDREWRDSSWEFQVKLSRARVVLIGVGGVGSTAALALAMSGVGTLHCVEPD
                     VITLSNLNRQILYTEQDLGRRKVEVAVERLRAANSTIKVTGEPTRIDSLESLRTLAAEY
                     DVLIVSADRPKAIRSWANQACVATGTPWVFGGYHGPQASLGLYRPGTGPCFECANAADR
                     ERDARRPKTGMWLPAEETPQVHAANAATAGMVGNLVAHVVMSVLTGAPPLPVNCQYGYS
                     LATMDHSFITDVERPHPQCPLCNAA"
     misc_feature    complement(10038..10053)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.9"
                     /tool="antismash"
     misc_feature    complement(10044..10056)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.11"
                     /tool="antismash"
     gene            complement(11115..11993)
                     /locus_tag="YIM_RS37680"
                     /old_locus_tag="YIM_37885"
     CDS             complement(11115..11993)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005164754.1"
                     /locus_tag="YIM_RS37680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37885"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_153034919.1"
                     /transl_table=11
                     /translation="MVTSPAPGSDRARLATKLREIRAVTGMSGNQFAAHIGWPQSRVSK
                     IETGVQFPTDQDVADWLEAARAHDQRDAVAALLARARVENVAFRKVVKESGSAGFLQRL
                     AGGREKQATRICDFLPAMIPGLLQTPAYTRELLSLPSGPASLGAAVTDDDLARMVAFRI
                     ERQSVLYDNTKTVSFVVGEAALWTRIGGVDTQRGQLDRLHSIAELGTVDLRIVPFTTAM
                     PVFPLHGFRIYDDEAVDIETITGSQTLADPDDVAEYVRFFSHLQAAAVAGRDAVQLIQR
                     VSRRLGSETGE"
     gene            12471..13130
                     /locus_tag="YIM_RS37685"
                     /old_locus_tag="YIM_37890"
     CDS             12471..13130
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS37685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_37890"
                     /product="adenylate/guanylate cyclase domain-containing
                     protein"
                     /protein_id="WP_153034920.1"
                     /transl_table=11
                     /translation="MNPTPTQAYDRFPALPRHRTVVAVDVEGSTRRTNHRRARMREALY
                     DLVENALLAAGIAEGHRDPLIDRGDGILILIRPADSVPKAIILSRMIPALAALLATHAR
                     QNPSRLRLRAAVHTGEVHYDRHGCYGDAIDLTFRLLDAPHLKSALAAAPDELAVVASED
                     VYRAVIRHEYDGLDKRTFRPEIDVRMGGERYLGWVQTTFAAMAGGTAQSRVGVLTR"
     gene            complement(13175..14698)
                     /locus_tag="YIM_RS37690"
                     /old_locus_tag="YIM_37895"
     CDS             complement(13175..14698)
                     /GO_function="GO:0046556 - alpha-L-arabinofuranosidase
                     activity [Evidence IEA]"
                     /GO_process="GO:0046373 - L-arabinose metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003096720.1"
                     /locus_tag="YIM_RS37690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37895"
                     /product="non-reducing end alpha-L-arabinofuranosidase
                     family hydrolase"
                     /protein_id="WP_153034921.1"
                     /transl_table=11
                     /translation="MSSMGQAPPTVSLRAAPRRTGRIRRSRWGGALITLLATVLAASTA
                     VAVNPGVASAATVDTAAWYVLVNRNSGKALDVAGVSTADGAVVQQWARHDGANQQWQFV
                     DSGDGYYRLKSKNSGKVLDIDNWSTADGGKVQQWTDLNGTNQQFRLTDSDGGYVRLINR
                     HSGKAVEVSGQSTADGAAAIQSGDQNVASQQWQLVKLNDAPGACALPSTYKWSSSGPLA
                     QPKSGWVSLKDFTNVVHNGKHLVYGTTHDFGTSWGSMNFSLFSNWSDMGSASQNAMNSG
                     TVAPTLLYFAPKNIWVLAYQWGGPAFSYKTSTDPTNPNGWSAPQTLSTASITGSGTGPI
                     DQTLIADGQNMYLFFAGDNGKIYRSSMPLGNFPGNFGSSYTTIMSDTTNNLFEAVEVYK
                     VQGQNQYLMIVEAIGSNGRYFRSFTSNNLGGSWTPQAATESNPFAGKANSGATWTNDIS
                     HGDLVRTNPDQTKTIDPCNLQLLYQGRDPKSGGDYGLLPYRPGLLTLKP"
     gene            complement(14733..15956)
                     /locus_tag="YIM_RS37695"
                     /old_locus_tag="YIM_37900"
     CDS             complement(14733..15956)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007032127.1"
                     /locus_tag="YIM_RS37695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37900"
                     /product="sorbosone dehydrogenase family protein"
                     /protein_id="WP_153034922.1"
                     /transl_table=11
                     /translation="MSRRRCRPVTVLAGLLVLALSALLLPSVSARSTAAAGTTHPGAVP
                     LTELTVVSEQVASGLRRPIAITGLPDGRMLIAEKNGTVRAYHPDTGLAPDPVLDLTARI
                     DTSDNERGLLGITPAPDFASTGMLYVSYTSLPAGALTLARLPIGAPDQVQVLLTQEHAE
                     YGNHNGGQVAFGRDGHLYWSTGDGGHANDPFKAGQNLGTLLGKIVRIDVNRACGAKPYC
                     VPFNNPFVRTPGARPEIWLYGLRNPWRFSVDPVDGSLWIGDVGQGLVEEINHIRPWQGG
                     ANLGWSCREGTPVFDPEQCQPGGKYTDPVFEYDHYNDNCSVTGGVVYRGAKTPEARGTY
                     VASDYCSTRVFAVRPKLSGGYESAVIGNFPTQPTAIGTDVHGELYVLSDLPGWLNRVRF
                     ERVQPANH"
     misc_feature    complement(15990..16004)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 29.02"
                     /tool="antismash"
     misc_feature    15991..16005
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 28.15"
                     /tool="antismash"
     misc_feature    complement(16046..16060)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 24.69"
                     /tool="antismash"
     misc_feature    16047..16061
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 26.66"
                     /tool="antismash"
     gene            complement(16180..17403)
                     /locus_tag="YIM_RS37700"
                     /old_locus_tag="YIM_37905"
     CDS             complement(16180..17403)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS37700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_37905"
                     /product="hypothetical protein"
                     /protein_id="WP_153034923.1"
                     /transl_table=11
                     /translation="MRLPRLVALAACAFLVMTACTSTDGGAEGEIADPDEVTLGETVLA
                     FYLSPDTSVDNAKDGQPGYLVLVRADGGKRLIETSGMTEAHIAWSETGLFFSDDTRDYL
                     LGKDGLVGFENKKAGHQQSAFALPENKGFVAVYNEGFSDSGYTNQVAVTTSTGSQLYQV
                     EGNYFMNALCGGVLNGIATDTGTHFADSATIPGMRSKVDPSAQPELLSQLYPATEGRER
                     VVAWRGVFDAGDHNRHVPCHDGVITFLSDYTDADGNPHLTVVSWDTGTGAYAEQALVDA
                     RRRPIAEELVDPGTFSQKSYDARAVRSGHLEWLAADGRLMSTEIASGITRPRFDTTFTS
                     GSDTSSQAIFTDRSIHVVQETFDGETPVKIKRFDRVTGDLAAEISVPGLAEHGIEFNLR
                     GAAVPPTA"
     gene            complement(17470..18042)
                     /locus_tag="YIM_RS37705"
                     /old_locus_tag="YIM_37910"
     CDS             complement(17470..18042)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017519.4"
                     /locus_tag="YIM_RS37705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37910"
                     /product="YiiX/YebB-like N1pC/P60 family cysteine
                     hydrolase"
                     /protein_id="WP_194239880.1"
                     /transl_table=11
                     /translation="MTATIVAGAAMAGLLAGPAQAAEADTSSPVGTASSDDGACKTKKT
                     VGKAKNKGDVFHSYAQTAVFKHNHIGIYYTTNTIVEAPGKGQKSKSVTASTLKKCGPIY
                     KMYVEAKQSSRDKAANYAYNNLRDKEYDSNFVTNKTSNNTKLNCSELVWKAYKKAVDIE
                     LDGDGGLGVFPNDIKNDGSTEIYETIK"
     gene            complement(18337..18744)
                     /locus_tag="YIM_RS37710"
                     /old_locus_tag="YIM_37915"
     CDS             complement(18337..18744)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009156233.1"
                     /locus_tag="YIM_RS37710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37915"
                     /product="hypothetical protein"
                     /protein_id="WP_153034925.1"
                     /transl_table=11
                     /translation="MGLAKVWVRTLSDGIVRADQIVSLTSHSTPALSGKPARWLLDATV
                     AVSTGSGHAGSWSVGMLHRTLIQTPAEPVDAPEALARLLAALHDTEAAGIITPLPAEPS
                     ETGRSGVRFSFAPFNDTGSPLDLGDTASSKP"
     gene            19095..19505
                     /locus_tag="YIM_RS37715"
                     /old_locus_tag="YIM_37920"
     CDS             19095..19505
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013868.4"
                     /locus_tag="YIM_RS37715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_37920"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_153034926.1"
                     /transl_table=11
                     /translation="MTATLSATFHSGESVLVLSGDLDRRSAPALRDLLHARITLGQDFV
                     LDLRSISFFGVAALAELLRAANSAAQHDVNWTMVTWGSVVDRTIDATGTRTVLETRPDL
                     AGALANLRGRRHHPGTIPAHVPTRPFRTDKPD"
ORIGIN
        1 tgccacgacc tcgtacgcgc cgcggcaact tgggccggac gactcgacac cgtggtcaac
       61 aacgccggaa tccaacccgt cgaagacctg cccggcatgg ccgccgacag ctggaacgcc
      121 gtgatccgga ccgacctgac cagcgcgttc tcctgcacgc aagccgccgc cggggtgatg
      181 gccgacgccg gcggcagcat catccacatc gcgtccatcg aagccaccca gcccgcgccg
      241 gggcacgcgc actacagctc cgccaaggcc gcgctcgtca tgcacgcccg cgcggcggca
      301 ctcgaatacg ggccgcgccg catccgggtc aacaccgtct cacccggcct gatcgaccgg
      361 ccgggcctgg ccaccgactg gcccgacggc gtccgccgct ggcagcacgc cgctcccctg
      421 acccgcctcg gcacccccgc cgacgtcgcc aacgcctgcg ttttcctcgc ctcaccactg
      481 gcgagctgga tcaccggcca caacctcgtc gtcgacggcg gcgtctccgc ccgtcccacc
      541 tggtagccag ggctctactc gtccacagtg gacgctgaag gcgcgtggtc gaggtccgcc
      601 agcagcgcca gcaacccggg gaaccggccc tcgaactcgt cacgcagtcg cacgaaggtg
      661 ccgttaccgg cgttccgctg ccggaccagt cccgcgtcgc ggagcacgcg ccagtggtgc
      721 gtgcgggtcg acttcgcctt gggcagcgcg aaagacgcgc aggcgcgctc cgcccctccg
      781 ccgctcaaca acgcgaggac cacctgccgc cgatgcgggt ccgccagcgc ggacagcacc
      841 gtcccgagcg ccacctcgcc gatcggcgga accggaaact catccaccat caccacctgg
      901 acatggtacg acaaatctcg taccgtgaag gtaccaatcc actcgtacca tccgaggtga
      961 ccgtgctctg cgtgttcgac atcaacgaaa ccctgctcga cctcgccccg ctcgacgacg
     1021 tgttcggctc ggcggaagcc aggcgcgcgt ggttcgccca ggtgatccac accgcgctga
     1081 ccatcaccgc gaccggtggt taccgcgact tcgcggccat cgccggtgcg gccgccgacg
     1141 aggatgtgcg ccccaaggtc ggccccgtgc tccgcggcct tccggcccac ccggacgttc
     1201 ccggcggcct cacccgcctg cgcgaggccg ggttcaccct ggtcgccctg ggcaactcac
     1261 cgctggccac catcgaggcg cagatgagca actccggact ccgcgaccat ttcaccgcgg
     1321 tgttctccgc ggaacaggcc ggcgccctca aaccggccgc ggcgccgtac cgcaccgtgc
     1381 tcggcgccta ccccggccag gacgcgatca tgatcgccgc gcacggctgg gacatcgccg
     1441 gagccgcggc cgcggggctg cgcaccgcct ttgtcgaacg accggggcag cgccaactgc
     1501 ccggcggccc cacggccgac ttcagcgcgc ccgacatcga agtactcgcc accaaactga
     1561 tcgaagcagg caccgcgcgc tgaccggagt tacggcggac tgatggcagt gagcaaacgg
     1621 gcgagcttcc acggccgtgg cccccaagcg gcgagttgcc cgccgacaag cggtttccac
     1681 agtccgcgcc tgccgatgaa caccagcatg agggccgagg ggtcggcgcg gatatgggca
     1741 tcgacagcac gcgcggaacc cggatccagc gtcagcgaac cacggtcgaa gaccatcgtc
     1801 gtgcggccgc caccccgcag acgcagttcg aaacggcctc ggaaggcacc cgccttttct
     1861 tgatcgacaa aagccgtggg cggcaaggct tcgatgagcg gaagcacgcc accttcgacc
     1921 gcgagcaccg cgtggtggcg tgaaatcgcc cacggacggc cgacggcttc ggcgatgtca
     1981 tggccgtgca tcaggcattc ctcgagcaga tggcacgcca ccaccgacgg cggaacgcga
     2041 acgccttgca gccatccggt ggtggccgtg cgcgagcacg agacgacgtc gtcgaactcg
     2101 acggccagcg ccccgagccg gtccgcgagt gccgccgggt cccgttcctc gtcccgggtc
     2161 agcatcttcg cgttgacctc ggccatgccc gctgacgtca cgacggcgtc cgggaccggt
     2221 ttcccggcga tggcgtcggt gtcgaaccgg aagacgtggg acaggtgagc cgcgacctca
     2281 ccgaccgtcc aggcaccgac cgaagccgaa cccgcgtcgg gaatgctccg caccagttcg
     2341 aacagacggg gaacgacttc ccgcacggcg gcgcgagcct gcgccagggt ccccgaaacc
     2401 gcgtcagcca tgaccattcc ccctcctcac cgacgtgctg gatattgtca ggttcacttg
     2461 agattgtaaa gtggacggtg ggagcggctc gctgtcgcgc tgcacgtccg gcgcaccacc
     2521 gagtccgggc gttaggatgg ttggcgactt cgaggattcg agcagaagca ggagcagggc
     2581 gtgcccatct cgccgtcgcg actcacgctg gcacgcaagt tgcgggccat gacgctggcg
     2641 gatctgagca gcctcaccga tctcagtcca caaacgatca accgctgcga actcggccac
     2701 caggaaccga cggccgacag cgtcaaccgc ctcgccgacg cactgaagct gccgcccgcg
     2761 ttcttccacc ggcccgacgt ggagccgctt ccgaccgcga cggcgagcct gcgctcaccg
     2821 agcaagacct ccgcgttccg ccgcgacgcg gtgctcgccg ccgccctgat cgcctcggag
     2881 atcgccgcct ggatcggcgc ccggttccgg ttgccacggg cgaacctgcc cacggccccg
     2941 gcgaacccgt cggccgagga catcgaagcg atggcgcggc gcatccggaa cgagtggggc
     3001 ctcgggcagc ggccgatccc caacctgatc cacctgctcg aatcccgcgg ggtgcggatc
     3061 ttctcgctcg tgcaggaagt ccgcgacgtc gacgcgttct ccgtcttcct ccgcggcgag
     3121 ccgttcatct tcatcgacac cggcaaaacc gccgagcgcc agcgcttcga cgccgcccac
     3181 gaactcggcc acctcgtcct ccaccagggg ccgggacgaa tcgacggacg cgaggccgaa
     3241 cgccaggcgg accgcttcgc cgccgccctg ctcatgcccc gcggtgacgt gctcgcccgc
     3301 aacctgcacc aggccgacgc cgcccggctc cgccaggcca gccggcgctg gggcgtctcg
     3361 ccgatggcac tggcccaccg gctgtccgaa ctggacatca tcacccgctg gcgctaccgc
     3421 accctctgcc ccgaactggc cgaaagcggc agccatctca ccgcggaaac ctcgcaggtg
     3481 ctggaaaagg tgttcgccca cctgcgccgc tccgagcgcg gggtccgcgc catcgccgac
     3541 gacctcgaac tgacccccga ggagttcaac cgccacgtct tcggactggc cgcggtgcac
     3601 ctccacgcgg tggccccggc cggcgtcgcc cagtcctcgc ggtgcgccgg gtagcttcct
     3661 ccagcgcctg aatcgatatc ccggcgacgg ttcccgccgg aaacaggtcg atcaacctag
     3721 attgatgtat tatccgaacc gtgccgacca ccgagacagc cgagccgccg ccgttcgtgc
     3781 ggctggccgg agatccgctg cgctggcagc tgctgcgcca actggcgcac ggtgatcgcc
     3841 gggtgcgcga actggtggag gcggtcgggc aaccgcagaa cctggtgtcc taccacctgc
     3901 gcaagctgcg ggccgcggaa ctggtcaccg cgcggcggag cagcttcgac ggccgggaca
     3961 cctactacca cctcgatctc tcgcggtgcg cggacgcgct cgccgagacc gggatcgccc
     4021 tgcaccccgg tctcgcgccg ggccgggtga accggacgcg atccaccgcc cggctgaagg
     4081 tgttgttcgt gtgcacgggg aacagcggcc gctctccgat ggccgcggcg ctgttgcgac
     4141 atcgggccgg tccgtcggtc gaggtgttca gcgcgggcag cgcgccgaag ccactgcact
     4201 cggaggcggt gcgcgcgctc gccgggtacc gcgtcccgct cacccacgaa ccgacccatg
     4261 tggacagtct tcgccgcagg cggttccact gggtgatcac cttgtgcgac cgggcccgtg
     4321 aggtctgccc ggagttcccc ggtcaccccc gcgtgctcca ctggagcctg ccggacccgg
     4381 caaaggaaac cgacgacgcg ggcgaaaccc ttccggcgtt ccgccgcctc gcgggcgaac
     4441 tggaccgccg gatcggcttc ctgctccccc gcttcggcat gtccgccgaa gcggaaagcc
     4501 gaatctagaa cagaaaggcg gaagcgcatg acgtcggatc tggtgagcgt gcgttacctg
     4561 gtcgacgagg tcgaggccgc cgtcgagttc tacaccgagc acctcgggtt caccatcaac
     4621 accaacgcga taccggcgtt cgcggacgtg gtgcgcggca acctccggct gctcctcagc
     4681 ggcccggcca gttccgccgg gcgcccgatg cccgacggca ccaagcccgg acccggtggc
     4741 tggaaccgga tccacctcat cgtcgacgac atcgatgccg aggtcgcccg gctgcgcgcg
     4801 gcgggcatcc ggttccgcag cgacgtggtc agcgggcccg gtggccgtca gatcgtgttc
     4861 gacgacccgg cgggcaaccc ggtcgaactg ttccagcccg ccgcccggtg aagcgggccg
     4921 ccggtaaggc cctcggttac cggtattgac agaacctttc cccgattctc gttttccggt
     4981 agcatgtacg gccgcgcaat tggcgcggtt ccgtgttgtc tcacgtcgcc tcacgtcgtc
     5041 ccgcattctg gatgttttac cggaggttta ccggccatcc ggttggttga tcatggagct
     5101 gacagtggtc agcgggcaga gttgccgttc cgactcgatt tccgggcttt cacgcagagt
     5161 taactgcgga gacggggcag tgcccgtttt gcctgttagc cttgaccaac ggcaggaaat
     5221 cgagacacaa catccgcggg aaagggggcg aatcgtgctg ggctcgacca aattccggtt
     5281 gctgctgctg gccgggctgc tggccttgca gttcctggcc cccgcgctcg ctcccggcac
     5341 cccgtcggtc gcgctgaacg ggatcaccga cgccaccgat gccaccgcga ccgccgccga
     5401 gcggtccgag cccgaacacg ccgtgtgcga ctcgccggat cccacctccc ccaacggtct
     5461 tccgcgcacg cgcgaccggt atcgcgcccc ggccgacctc tccccgcaac cggtcgcgcg
     5521 ccccgcgtcg acctgcgccg acgtggccgc gcgcccgccc accgcggtcg tcgcgctcgc
     5581 ccggccgcca cacctcggcg cgtccgccgc cgattccgcc gcggtgctcc aggttttccg
     5641 ccgctgagcc gttcaccacg atcgatcacc cgccacgtcc gtcgatgacg ccgacgtggg
     5701 ggcacgtcgc tgtgcccgaa tcgagttccg ttgcccgaca ccgacgcgcc ggccaatggc
     5761 gcgccaggag gaattcccga aatgcagtcg ctgatcgagc acgcccgttc cttccgacgg
     5821 cagtgcgagg accgcgccga acagttcgcg cggctggccg acggccagtc accgcaggtc
     5881 ctgtttgtca cctgttccga ttcgcgggtc gttccggccc tgatcaccgg cgcccgtccc
     5941 ggtgaactct tcgaactgcg caccgcgggc aacatcgtgc ccccgtacgc cgccggccgg
     6001 cccagcggcg aggtggccac catcgaatac gcggtggaag tgctcggggt caccgacatc
     6061 gtggtctgcg gccactcgca ctgcggcgcc gtcggcgcgc tggtgcgcgg tgacgacctg
     6121 accgccgtgc ccgccgtgca cggctggctc tcccacgcca cgccccgtcc ggaagggacg
     6181 gtcgaggacc cggccgtcgc cgacgcggtg cagaaccacg tgctgaccca ggtgctgcgg
     6241 ctgcgctcgt acccgggcat cgaccggcgc ctgagcgcgg gtgaggtccg gctgcacggc
     6301 tggttctacg aagtgcacac gggatccgtg ctggcccacg actccgacac cgacaccttc
     6361 caggcgctgt gaggaccact gtggaccttc gaacgaaatt cccccatctg cgccaggact
     6421 tcaccgcgtc gctggtggtc ttcctggtcg ccctgccgct gtgcgtcggt gtcgccgtcg
     6481 cctccggggt cccggccgaa ctcggcctga tcaccggcat cgtcggcggc atcgtcaccg
     6541 ggctcatgcg cggcagcagt ctccaggtgt ccggcccggc cgccgggctg accgtgctgg
     6601 tcttcgaagc cgtccgccag ttcggcctgc ccgcgctcgg cgtcatcgtg ctggccgccg
     6661 ggctgctcca gctcgccatg ggcgcgctga aactgggccg ctggttccgc gccatctcgg
     6721 tctcggtggt cgaaggcatg ctggcgggca tcggcctggt gctgatcgcg ggccagcttt
     6781 acaccgccgc cggcctgacc gcgccggcgt ccggtatcgg caagctggcc ggactgcccg
     6841 gggcggtggc cgaggtcgtc gggaacccca ccgcgctcgc ctcgatcgcg ctcggcgccg
     6901 gaaccatcgc cgtgctggtg ctgtggaagc ggatgccgaa acgggtgcag gccgtgccgg
     6961 gcccgctcgc cgcggtcggg ctggcgtcgg tcgtctcgct ggtgttcagc ctgccggtcg
     7021 ccacggtcga ggtgcagggc ctgctcggcg ccatccagct gcccgagctg gcctctttcg
     7081 gtgaactggc gaacctgagc ctgatcggca ccatcctggc cttcacgctg atcgcgtcgg
     7141 ccgaaagcct gttcagcgcg gccgcggtcg accggctgca caacggtccg cgcaccgagt
     7201 acgacaagga gctgatggcg cagggcaccg gcaacaccgt gtgcggtgtg ctcggcgcgc
     7261 tcccgatgac cgcggtcatc gtgcgcagct ccgcgaacgt ccaggcgggc gcgaagacga
     7321 aggcctcccg ggtcctgcac ggtgtgtggc tgctgctgtt cgcggcgctt ctgcccggca
     7381 cgctggcgct catcccgttg cccgcgctcg cgggcctgct ggtgcacgcg ggctggaagc
     7441 tgatcccgct gcgctcgatc gcggcgctgt ggcgtgagca ccggggtgag gcgctgatcc
     7501 tcgtggtcac cgcggtgtcg atcgtcgcgg tgaacatgtt cgaaggcgtg ctgatcggcc
     7561 tggccctgtc cgtggccaaa acggcttggg aggcctcgca cctcaagctg gaggtcatcg
     7621 acaagggtgc cggtcccatc caggcgtacc tgtcggggaa cgcgaccttc ctgcgcctgc
     7681 cgaagatcct cgacgacctg gaggcgctgc cgcgtgaccg cccgatcgaa ctggacctgt
     7741 ccggcctgca ccacctcgac cacgcctgcc gcacggcact ggaaacctgg tcggcccagc
     7801 acagcgccgg ccccgaccgg gtgaaggtaa ccgcgtccgc caccagcggc tgacctgtgg
     7861 tggctgggag gcgatccctc ccagccacca cccgaaggcg gccgcagcgg tcaagccgcc
     7921 gcttgtttcc tagaatccgc agtcgagatc acgatgcggg tattccgtct tgttgggcag
     7981 atcggcaatt ccgaccacgt cgacgtcgac taccgcacgc cattttgttt tcgcggtgtt
     8041 gcggcacgtg taacgggcat tcgcgcgggc gaccgacccg cctccggcat aaacccgctt
     8101 ctccccctcg gaccgggtgg tccactcctt gccgtccagg ctggtctgca ggtagacggt
     8161 gacgtcggcc ttgttcccgc tggccttgac acagtcggca ggcaccggct tgacccagtc
     8221 ccaccagcca tgcacgctgg cgtcgcccct ggtcacgtgc gggtagtccg cgagctgctg
     8281 gaacgcgcag accgcctcca ccggctccac cggctccacg gcggacgcgg tgtgcgccgc
     8341 ggcgaccgga atgagcagga ataccgcggc ggcgctcgcc acggaaatca tacgattgcg
     8401 gttcatttga atccccctca agaacgtgcc tggttccggc cagactgctc gatctcgatt
     8461 agagtaaggc gatgttcgtg cgaacggcga cacccacaag gaggatgaag tgcctgaatt
     8521 cgatccttcg tcacgaaccc tgctcgtgga tggcgaaacg ttcgaagtcc accacgatcc
     8581 ggatcaaccc ggcgtgcacc agctgacctg gaccaccggc ccgaacgcgg gatacggatt
     8641 ctcgatcgcg cgctccgacc acgccgaaat cggcgacgcg gaactgatcg cccaagcccg
     8701 cgagttcctg gccggcatcg acccggccac cggcttcctg tccgagtgac ccgctcgtct
     8761 cggtcacgac cacttcccgg gcgttgggcc atcggcgtcg gtcgtccgtt ggtgtcgcgt
     8821 tctggcgtta gggtgtggaa aaggcacgaa cccgtgcgca aagctcgctg actgctacgg
     8881 cgcggtcctc ccgatgcagt ctgtgaggta gctgattgcg ctatggcttt ctgcgtgcag
     8941 gtggcacact ctggagatgt ctagccgtct acaggagcga ggcagacatg ttggagcttg
     9001 gccaggtgga tcgacgggcg gacaccccgc cctaccgcca gatcgcagcg atgctcatcg
     9061 aggccatcga cgatggccga ctggagccag ggcagaagct tccttccgag gccgcgttga
     9121 tcgagcattt cggcgtagcc cgcatgacgg tccggcaggc gacccaggag ttgcggcgcc
     9181 aaggcctggt ggtggccgaa cacgggcgcg gggtgttcgt gcgctcgcct tcctccacgc
     9241 tacccgtgcg acgagtggcg tccgaccggt tcgcgcgcaa gcatcgccag gcaggcaagg
     9301 cggcgttcct ggccgacgcg gaaaagctcg gctaccagcc gagcgtcgac cggatccagg
     9361 tccggcgcga gacggccccg ccgatggtgg ccgagcggct gcgcgtggat cccgacgacg
     9421 aggtggtggt gcgcgatcgc cgctacctgg ccaacggtcg tcccatcgag atggccacct
     9481 catacgtgcc aacggaactg gccgagggaa cgcagatcct cgaaatcaat ccgggccccg
     9541 gcggcatcta cgcccgattg gaggaacgcg gacacaagct ggcctcgttc accgaagagg
     9601 tgacagcgcg gatgccgaat tcgcgcgagg tgcgcgagct gggccttccc gaaggtgcac
     9661 cggtgctgac cgtgatccgc actgccttcg acaccgacgg agcagtggtc gaggtctgcg
     9721 acatcgtcaa ggcggcttcg tcctacgtgc tcgagtacga ctttcccgcc aagtaaccac
     9781 ccgttacccc gaacgagtgc ccagctgtga ctcgtccagg ggctaggaac tcctctagac
     9841 gactagtaca gtttggttcg aatccccaga cttgcgcgcc cttcgccacg aaaaggggag
     9901 ggaggagtgc cgccatgatc gagatttcga tggtggagcg cgaggacgcg aaacgccacg
     9961 tgtactgcga taccggtagc tagaggcgag gaggcccggg atgcggctgc ggatcaagct
    10021 ggaacaccgc ccggtgcggt tcggtgacgg cgtcatccag atcggcggcg aactgttcgg
    10081 catcgccggc aagctgcacg acccggatgg cgccgtatgg gcgcttctgg gtctcctcga
    10141 tggttcacgg acggtggatc aggttgtcac cgacctgatc caccgcttcc ccgaacattc
    10201 ggtccagatg gtgctcgacg ggatcgagac gctggccaag gccggctatc tcgaagacgt
    10261 cgacgagccg gaatgcgcgg cattgagcac ctggcaacgg gagcgttatg gccgcggccg
    10321 cgcgttgaac cagtgggtgg accgggaatg gcgggattcc agctgggaat tccaggtcaa
    10381 gctctcccgg gcgcgggtgg tcctgatcgg ggtgggcggc gtgggcagca ccgcggcact
    10441 ggcgctggcc atgtcgggcg tgggcacgct gcactgcgtc gaaccggacg tgatcacgct
    10501 gtccaatctc aaccgccaga tcctctacac cgagcaggac ctgggacgcc ggaaggtcga
    10561 ggtggcggtg gagcggctgc gcgcggcgaa ctccaccatc aaggtcaccg gggagcccac
    10621 ccgcatcgac agcctggagt ccctgcggac gctggcggcg gagtacgacg tgctgattgt
    10681 gagcgccgac cggccgaagg cgatcaggtc gtgggccaat caggcctgcg tcgcgacggg
    10741 caccccgtgg gtgttcggtg gttaccacgg tccccaagcc agcctggggt tgtaccggcc
    10801 cggcaccgga ccctgcttcg agtgcgcgaa cgccgccgac cgcgagcgcg acgcacgccg
    10861 gccgaagacc ggaatgtggc tgcccgccga ggaaacacct caggtgcacg cggcgaacgc
    10921 ggccaccgcg ggaatggtgg gcaatctggt ggcccacgtg gtgatgagcg tgctcaccgg
    10981 cgctcccccg ctccccgtca actgccagta cggctacagc ctcgcgacca tggaccacag
    11041 cttcatcacc gacgtcgagc gcccgcatcc gcagtgcccg ctctgcaacg cggcctgacc
    11101 tcgcggtacc ccacctactc cccggtctca ctccccagcc ggcgcgagac acgctggatc
    11161 agctgaaccg cgtctcgtcc ggcgacggcc gcggcttgaa ggtggctgaa gaaccgcacg
    11221 tattccgcca cgtcgtcggg gtccgcaagc gtctgcgacc cggtgatggt ctcgatgtcg
    11281 acggcttcgt cgtcgtagat cctgaacccg tgcagcggga agaccggcat cgcggtggtg
    11341 aagggcacga tccggagatc aacggtgccg agttcggcga tggagtggag ccggtccaac
    11401 tgcccgcgct gggtgtcgac gccgccgatg cgcgtccaca gcgcagcctc ccccacgacg
    11461 aacgacacgg tcttggtgtt gtcgtagagc acggattgcc gctcgatccg gaacgccacc
    11521 atcctggcga gatcatcatc ggtcaccgcg gcgccgagcg acgcgggccc ggagggcaac
    11581 gacagcagtt cccgcgtgta ggcaggggtt tggagcagac cagggatcat cgctggaaga
    11641 aagtcgcaga tccgggtcgc ctgcttctca cgcccaccgg cgagccgttg cagaaaaccg
    11701 gcactgccgg actccttgac caccttccgg aaggcgacgt tttccacccg ggcacgggcc
    11761 agcagcgcgg ccacggcgtc ccgctggtcg tgcgcccgcg ccgcttcgag ccagtcggcg
    11821 acgtcctggt cggtggggaa ctgcaccccg gtttcgattt tggacacccg cgactgcggc
    11881 cagccgatgt gcgcggcgaa ctggttgccg gacatgccgg tcaccgcgcg gatctcgcgc
    11941 agcttcgtgg cgagccgagc acggtcgctt ccgggtgcgg gcgaggtaac catctgctcg
    12001 gccgagttca ggcgccggcg cgagccggcc gaacacgttc gtgagacacc agcaccccga
    12061 tcggagcaac aagcaagatc gtctgctcaa catgcttacg caaagtccaa cctccgcacc
    12121 agttgatcat tccgcatagc tcgatagtaa caagcgaata gaacctgaat ggttgatggc
    12181 aaattcgaat agctggagaa taacctatcg aggtcaggac ttccaccgag gagtcaccgc
    12241 cctctccagt tacccacctg aatcagcgcg gcgccagctc ctggcgatgg gagcgaggcc
    12301 cggcgtcaca gccagctcgg caaaagggtg cgcaaggagc tggacatgcc gccgggcgag
    12361 gggaatccca tcgcggcgac gcgcggcccc ggccgttcca cgacccccgt ctggaacggc
    12421 cggggtgacc cagtcccgga caatccgcga agcgacacgt ggtgacacag atgaatccca
    12481 cgcccacgca ggcgtacgac cgcttccccg ccttgccgcg ccaccgcacc gtcgtcgcgg
    12541 tcgatgtcga aggctccacc aggcggacca accaccggcg agcccgcatg cgggaagccc
    12601 tctacgacct ggtcgagaac gccctgctgg ccgccgggat cgccgaaggc caccgggatc
    12661 cgctgatcga ccgcggcgac ggcatcctca tcctgatccg ccccgccgac tccgtaccca
    12721 aggcgatcat cctgagccgg atgatccccg cactggccgc gctgctcgcc acccacgccc
    12781 ggcagaaccc cagccggctg cggttgcgtg ccgccgtgca caccggcgag gtgcactacg
    12841 accgccacgg ctgctacggc gacgccatcg acctcacctt ccggctgctc gacgcaccac
    12901 acctcaaaag cgcgctcgcc gccgcgcccg acgagctggc ggtggtggct tcggaggacg
    12961 tctaccgggc cgtgatccgg cacgagtacg acggtctcga caagaggacc ttccgaccgg
    13021 agatcgacgt ccgcatgggc ggcgaaaggt atctcggctg ggttcagacg accttcgccg
    13081 cgatggccgg cggcacagcg caaagccggg tcggcgtcct cacccggtga ggagtgaggg
    13141 caccgacccg gctggtcgga gttgcgtcag gtgatcaggg cttcagcgtc agcaggcccg
    13201 gccggtacgg caggaggccg tagtcgccgc cggacttggg gtcgcggccc tggtagagca
    13261 gctgcaggtt gcagggatcg atggtcttgg tctggtcggg attggtgcgg accaggtcac
    13321 cgtggctgat gtcgttggtc cacgtggcac cgctgttggc cttgccggcg aaggggttgc
    13381 tctcggtggc ggcctgcggt gtccacgaac cgcccaggtt gttggaagtg aacgagcgga
    13441 agtaccgccc gttgctcccg atcgcctcga cgatcatcag gtactggttc tggccctgga
    13501 ccttgtagac ctcgacggct tcgaacaggt tgttcgtcgt gtcgctcatg atcgtggtgt
    13561 aggacgagcc gaagttgccc gggaagttcc cgaggggcat gctcgaccgg tagatcttgc
    13621 cgttgtcacc ggcgaagaac aggtacatgt tctggccgtc ggcgatgagc gtctggtcga
    13681 tgggcccggt gccggagccg gtgatgctgg cggtggacag cgtctgcggt gccgaccacc
    13741 cgttcgggtt ggtgggatcg gtcgacgtct tgtagctgaa agcgggccca ccccactggt
    13801 aggcgagcac ccagatgttc ttcggcgcga agtacagcag cgtgggtgcg acggtgccgg
    13861 agttcatcgc gttctgactg gccgagccca tgtccgacca gttcgagaaa aggctgaagt
    13921 tcatcgagcc ccagctcgtt ccgaagtcgt gcgtcgtgcc gtagaccagg tgcttgccgt
    13981 tgtggacgac gttggtgaag tccttgagcg agacccagcc cgatttcggc tgcgccagcg
    14041 gtcccgacga agaccacttg taggtcgacg gaagagcgca cgcgccaggc gcgtcgttca
    14101 gcttgacgag ttgccactgc tggctggcca cgttctggtc gccggactgg atggcggccg
    14161 ctccgtccgc ggtcgactga ccgctcacct ccacggcttt gccgctgtgg cggttgatca
    14221 gccggacgta gccgccgtcg gagtcggtga ggcggaactg ctggttggtt ccgttgaggt
    14281 cggtccactg ctggaccttc ccgccgtcgg cggtcgacca gttgtcgatg tcgagcacct
    14341 tgccggagtt cttcgactta agccggtagt agccgtcgcc ggagtccacg aactgccact
    14401 gctggttggc tccgtcgtgg cgggcccact gctggaccac cgctccgtcg gcggtggaaa
    14461 caccggcgac gtccagcgcc ttgccgctgt tgcggttgac cagtacgtac cacgcggccg
    14521 tgtcgacggt cgccgccgac gcgacgccgg gattgaccgc gaccgccgtg gaagccgcga
    14581 gaacggtcgc gagcagggtg atcagcgcgc cgccccaacg gctgcgccgg atacgaccgg
    14641 tacggcgggg tgccgcccgg agcgagacgg tcggcggggc ttgacccatc gaactcatgg
    14701 tgattctcct tcagcgtctg ggctgcacga gatcagtggt tggccggctg gacccgttcg
    14761 aaccgcaccc ggttcagcca tcccgggagg tcgctgagca cgtacaactc gccgtgcacg
    14821 tcggtgccga tcgcggtcgg ctgggtgggg aagttgccga tcacggcgga ttcgtagcca
    14881 ccgctgagct tggggcgcac ggcgaacaca cgggtcgagc agtagtcgct cgcgacgtag
    14941 gttccccgtg cctccggggt cttggctccc cggtacacca caccgccggt gaccgagcag
    15001 ttgtcgttgt agtggtcgta ttcgaagacc ggatcggtgt acttcccgcc cggctggcac
    15061 tgctccggat cgaacaccgg ggtgccctcc cggcaggacc agccgaggtt cgccccgccc
    15121 tgccacgggc ggatgtggtt gatctcctcg accaggccct ggccgacgtc accgatccac
    15181 agcgagccgt cgaccgggtc gacggagaac cgccacgggt tgcgcagccc gtagagccag
    15241 atctccggcc gcgcgcccgg cgtgcggacg aacgggttgt tgaacggcac gcagtagggc
    15301 ttcgccccgc aggcgcggtt gacgtcgatc cgcacgatct tgccgagcag ggtgccgagg
    15361 ttctgcccgg ccttgaacgg gtcgttggcg tggccgccgt cgccggtgga ccagtagagg
    15421 tgaccgtcgc ggccgaacgc cacctgcccg ccgttgtggt tgccgtactc ggcgtgctcc
    15481 tgggtgagca gcacctgcac ctgatcggga gcaccgatgg gcaatcgcgc cagggtcagc
    15541 gcgcccgcgg gcaggctcgt gtaggacacg tagagcatcc cggtcgacgc gaagtccggc
    15601 gcgggcgtga tgccgagcag gccgcgctcg ttgtccgagg tgtcgatccg ggcggtcagg
    15661 tcgagcaccg ggtcgggtgc caggccggtg tcggggtggt aggcgcggac ggtgccgttc
    15721 ttctccgcga tcagcatccg gccgtccggc agtccggtga tcgcgatcgg ccgccgcagg
    15781 ccggacgcca cctgttcgga gaccacggtc agctcggtga gcggcaccgc gccgggatgg
    15841 gtggtgccgg cagcggcggt acttcgcgcc gacaccgaag gcaacagcaa tgcggaaagt
    15901 gcgagcacga gcagtccagc cagcacggtg accgggcgac aacgccgtcg cgacatggtt
    15961 cagctcctcg agcaggtggg ggacacggtc tgggagcgct cccaatcgca ctggacaaca
    16021 caggcaagac cacgatcgcg cagatttggg agcgctccaa tagtagatcc ggcccagcgg
    16081 attcgactgc gccgatcggg cgtcgccccg ccgccgatcg gcggatcttc cgtgtgccac
    16141 cgacggtacg gctgctcttg ggatcgcgct ggccgcccgt caggcggtgg gtggaacggc
    16201 cgcgccgcga aggttgaact cgatgccgtg ctcggccagg ccgggcacgg agatctcggc
    16261 ggccaggtct ccggtgacgc ggtcgaaccg cttgatcttg acgggcgtct cgccgtcgaa
    16321 cgtctcctgg acgacgtgta tcgaccggtc cgtgaagatc gcctggctgg acgtgtcgct
    16381 gcccgaggtg aacgtggtgt cgaaccgcgg ccgggtgatc ccggaggcga tttcggtgct
    16441 catgagccgg ccgtcggcgg cgagccattc gaggtgacca cttcggaccg cccgtgcgtc
    16501 gtaggacttc tgggagaacg tcccggggtc gaccagttcc tcggcgatgg ggcgccgtcg
    16561 ggcgtcgaca agggcctgtt cggcgtaggc acccgtgccg gtgtcccagg aaacgacggt
    16621 caggtgggga ttgccgtcgg cgtcggtgta gtcggaaagg aacgtgatca caccgtcgtg
    16681 gcagggcacg tgacgattgt ggtctcccgc gtcgaagact cctcgccagg cgacgaccct
    16741 ttcccggcct tcggttgccg gatacagctg ggaaagcagc tccggctgcg cactgggatc
    16801 gaccttcgag cgcatgccgg gaatcgtcgc cgagtccgcg aaatgagttc ccgtgtcggt
    16861 ggcgattcca ttgaggacac caccgcacag cgcgttcatg aagtagtttc cttcgacctg
    16921 gtagagctgg gaaccggtcg aagtggtgac ggccacctga ttggtgtatc cggagtcgga
    16981 gaagccttcg ttgtagaccg cgacaaagcc cttgttttca ggcaacgcga aagccgactg
    17041 ctgatggccc gccttcttgt tctcgaaacc gaccaggccg tccttgccga ggaggtagtc
    17101 gcgtgtgtcg tcgctgaaga acagcccggt ctccgaccag gcgatatgcg cttcggtcat
    17161 gccgctggtt tcgatcagcc gtttgccgcc atccgcccgc accaggacca gatagcccgg
    17221 ttgcccgtcc ttcgcgttgt cgacggaagt gtcggggctg aggtagaacg cgagaacggt
    17281 ttcgccgagc gtcacctcat cgggatcggc gatctcgccc tccgctccgc cgtccgtcga
    17341 cgtgcaggcc gtcatgacca ggaatgcgca ggcggcaagc gcgacgagtc ggggaaggcg
    17401 caccggtcga gtcctctcgg gagacgggcg gcggcgcgac ccacgggccg caccgccgat
    17461 cggaggttgt tacttgatgg tctcgtagat ctcggtgctg ccgtcgttct tgatgtcgtt
    17521 ggggaagacg cccagcccgc cgtcgccgtc cagctcgatg tccacggcct tcttgtacgc
    17581 cttccacacc agttcggagc agttcagctt cgtgttgttg ctcgtcttgt tcgtcacgaa
    17641 gttgctgtcg tactccttgt cgcggagatt gttgtaggcg tagttggcgg ccttgtcgcg
    17701 gctggactgc tttgcctcga cgtacatctt gtagatggga ccgcacttct tcagcgtgga
    17761 tgccgtgacc gacttgctct tctggccctt tccgggtgcc tccacgatcg tgttcgtcgt
    17821 gtagtagatg ccgatgtggt tgtgcttgaa cacggcggtc tgcgcgtagg agtggaagac
    17881 gtcccccttg ttcttcgcct ttccgaccgt ctttttcgtc ttgcaggcac cgtcgtcgga
    17941 ggaagcggtg ccgaccgggc tcgacgtgtc cgcctccgcg gcctgggcgg gcccggcgag
    18001 caggccggcc attgccgctc ccgcgacaat ggtggccgtc atggaggcga gagttcgcct
    18061 gtttctggac atgtttgtct ccacttcgtg atcagtagac agtgacccca aggaaaatgc
    18121 gcgaaggcgc tagtcctgga acccccagtc cgttgccgaa gtgacgctaa accgcccggc
    18181 cacccccatg tgtcgggcgt tcaccctaca cacggtctcc cgccaaggaa accggtggca
    18241 cagggcaccg aatcaaattc tcggaatggc ctgggcaaac cggctgtgat catttccgcg
    18301 gcggaccgat ggaatcgatc tcgacgtgat cgcgcgtcac ggtttcgacg aggcggtgtc
    18361 gccgagatcc agcggtgagc cggtgtcgtt gaacggggcg aacgagaacc gcacgccgga
    18421 ccggccggtt tccgacggct ccgccggcag cggggtgatg atgccggcgg cttcggtgtc
    18481 gtgcagggcc gccagcaacc gcgcgagcgc ttcgggcgca tcgaccggct cggccggcgt
    18541 ctggatcagc gtgcggtgca gcatgcccac gctccagctg ccggcgtgcc cgctgccggt
    18601 ggacaccgcg acggtggcat cgagcagcca ccgcgcgggc ttgccggaca gggccggtgt
    18661 ggaatggctg gtcaaactca cgatctgatc ggcgcgcacg ataccgtcgc tcagcgtccg
    18721 cacccacacc ttggccaacc ccatcgtcgc ctccttcgcc tcccggatcg actggacttg
    18781 gcattctcac cgagagagtg ccaatttctc tcttagcacc caccccaggt gagccgcaag
    18841 attcgcgtcg acgcggcggg gtcccgctga ggagagtgct cggccgtggc gtctcccggc
    18901 aagacgacgc gggccgtgca cggaataatc ccggtcgcgg cattaatgaa tcgaatccag
    18961 ctgctgacag accgttcggg caacaattga tcccttttgt ctaatgcacc gcacatgcgc
    19021 actgccgcgg acatcggcgg aggcgtatcg tcgaagttgt ggctggacca gccctgctca
    19081 cggggaggtc aacaatgacc gcgacactgt cggcaacctt ccactccgga gaatccgtcc
    19141 tggtactgag cggcgacctg gaccgtcgtt cggcgccggc actgcgggat ctgctccacg
    19201 cgagaatcac cctcggtcag gattttgtgc tcgacctgcg cagtatcagc tttttcggcg
    19261 tcgcggcgct ggccgaactg ctgagggcgg cgaattcggc ggcccagcac gacgtcaact
    19321 ggaccatggt gacctggggt tcggtggtcg accggacgat cgatgccacc gggacccgca
    19381 ccgtgctcga gacccggccc gacctggccg gcgcactcgc caacctcagg gggcgacgtc
    19441 atcatccggg aacgattccg gcacacgtgc ccactcgacc gttccggaca gacaaaccgg
    19501 actgacacgg gcgttcgggg aacgccttgc cgccgatttc accacacgac agccatcggc
    19561 ttcccacgtt ccgtcactat ccggttccca gcgcgaaaca cgccgaaatc acaccgcggc
    19621 acgcccccgt tcacctgccc gatgccgaat caccctgccg accacgagcg tattggccaa
    19681 cccgtgaggg ccgcactgct gaacccagct cacttcacga tcggcccgtc atcgggcgcc
    19741 aagcagctct actcagcctt acagccacag tagttcgcgc gggaagtggt cgggcccggc
    19801 cgtgagtgcg gccgggcccg atcccggtga gctatcgctg gtacggccca ggcgaccccg
    19861 ggttcagggt cttcgcggac gacgaagatc ccggtttctc cgtggccggg caggacaggc
    19921 ccttccgcgg caccttcagc tcgagcaggt acgcgtccac cgcttcgttg acgcacgggc
    19981 tcggcccgtc gccgcggtag gcggtgtggc cccagccctc gtaggtgatc aggtgcgaac
    20041 cgctctgttt cgcggcggtt ttgttccacg cgtagaccgt cgccgggtcg tgcaagttgc
    20101 cgaccatgac cagcggcggc gcaccctcga tcttgagtgg cttctgcggg ttcgtcgtct
    20161 tcagcgggtc accggcgcag gtgagcgcgt ggtcgacgta gggactccac tccatgttcg
    20221 ggaacttcgc ggacaacttc gtgcgcagct tctcgtactc ggcgaagttc ttcaccgggt
    20281 agcgccagtc gctgcaccag atcggcggat acgggttgtt gatcgcggcg gccgcttcga
    20341 gtgacaacgg cgacggcgcg cccccgccgt ccttgaactt cttgagttcg gtagccaggt
    20401 tgccccacat tcccggcctg gtcaccgaaa acgtccgctg cgacagctcg tagaagtcga
    20461 tcggagcgcc cgtggccggg ttggtgagct tgcccgcttt ggcccgctcc ttcagttcgc
    20521 cgtagacctt cgcggtgccc tgcccgtgca gcgcgcaggc ttcggtggtg tcgcaccact
    20581 tcgcgaactc ctcgaaggcc acctccaccg gctcggtctc ggtccgcatg aagtcccacg
    20641 ccgtccgcag gctgtggtcc atgttgccgt cgttgaccat cgcccggatc cggtccggga
    20701 acagctccgc gtactgctgc cccatcagcg acccgtacga gtaaccgacg tagttgagct
    20761 tctcctcgcc gagcgcggcg cggatggcgt ccatgtcgcg cgcggtgttg aggttgtcga
    20821 cgtggtcgat cagctcaccg gaatgctcac ggcagctgtc catcagctgc ttgttgagcg
    20881 agaccaggtt gtcgaactcc gcctggctgg tgggccgccg ggcgtcgagt gcctgctgcg
    20941 acagcgtttc gtcgcagagc agttgctgac ttgtgttgat gccgcgcgga tcgaagccga
    21001 cgacgtcgaa gcgcgcggtc accgcctcgg tgaacgggtc ggcgttggcc accatgctca
    21061 cgccgctgcc accgggcccg ccggggtcga ccaggatc
//
