LOCUS       NZ_CP045480            21113 bp    DNA     circular CON 15-AUG-2024
DEFINITION  Amycolatopsis sp. YIM 10 chromosome, complete genome.
ACCESSION   NZ_CP045480
VERSION     NZ_CP045480.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. YIM 10
  ORGANISM  Amycolatopsis sp. YIM 10
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Complete genome sequence of Amycolatopsis sp. YIM 10, isolated from
            a rare earth mine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2019) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009429145.1-RS_2024_08_15
            Annotation Date                   :: 08/15/2024 04:03:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,775
            CDSs (total)                      :: 9,711
            Genes (coding)                    :: 9,634
            CDSs (with protein)               :: 9,634
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 22 of 77
            Pseudo Genes (incomplete)         :: 65 of 77
            Pseudo Genes (internal stop)      :: 1 of 77
            Pseudo Genes (multiple problems)  :: 11 of 77
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6387718
            Orig. end                         :: 6408831
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045480.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21113
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="23"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21113
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21113
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11113](-)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11113)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     misc_feature    267..282
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 19.99"
                     /tool="antismash"
     misc_feature    322..336
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            465..2309
                     /locus_tag="YIM_RS30125"
                     /old_locus_tag="YIM_30350"
     CDS             465..2309
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042625.2"
                     /locus_tag="YIM_RS30125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30350"
                     /product="DUF6541 family protein"
                     /protein_id="WP_153033552.1"
                     /transl_table=11
                     /translation="MTVLVAIGVLWLPGLAVAAAVRRTGWAVLGAAPALTFGLAGLAGP
                     LFSLLGVPWRWWSFLLFLAVVVTVAAIARPWLRGNTNAEPETWRRDGFLTIGPAAVVAA
                     AIGAVVVALGMRGGLDAVSQVWDMSFHGNAIRHITDSGDPAPAGLAAIAEDHPDFFYPN
                     GFHLIGSLAHGITGQPPPTVLNGLVIAVATLLVPLGTAALAAGLGLRAGAVAAAVVVST
                     TFANLPYLLWSYGGLYPYALALCLVGPALALAVRWLTSGDTGVLPMAVLAANGVLVVHP
                     SAAVVLAVFGVLVLLLRDRREFPLDWARLGVLLGLCALVLLPLLDGLLRVTPRVASFQP
                     FWAASSDAGTAVLRVVTLGGVVPQPGEAAPPAQWVLAVLVFGGLLLFLRVPAWRWATAA
                     ALVFAALYVLSVSTDHPVTRYLAAPWWNDSFRLVAVLPVVGAVAAGHLLDEVRRRLGDW
                     RAGVLILAGYLGATGGYAVANGDRVREMYRPGPVTPEVAAGLRRLTELVPPGTGVMNDN
                     GDGSTWAYGLVGRRTVVPYFGNYPPGSDRWVLLEKFDEVATDPGVRELVRRYDIGYAVV
                     ATPMLYGKERTPGLRELDQPPFRLVYENPGFRIYQLTG"
     gene            complement(2313..3140)
                     /locus_tag="YIM_RS30130"
                     /old_locus_tag="YIM_30355"
     CDS             complement(2313..3140)
                     /NRPS_PKS="Domain: PKS_KR (6-91). E-value: 5e-08. Score:
                     25.0. Matches aSDomain:
                     nrpspksdomains_YIM_RS30130_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018680430.1"
                     /locus_tag="YIM_RS30130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30355"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_153033553.1"
                     /transl_table=11
                     /translation="MTTSRIALVTGATQGLGLALAEGLARRLTARDVVYLTGRDSGRAA
                     EAAKSLSGAEVRGELLDVADPEAATRFAERLRDRHGGVDIVFGNAVMRVGPEDDPREII
                     DPYTQVNNFGTTRLLRAFAPLVRDNGRLIVVASSLGTLHQLAPVLHRRFDDLSTLDQVD
                     KQVVAWRDAVADGSARSGAWPGFVNIPSKIAQVAAVRALASQRRESDLARGILLAAVCP
                     GMINTPTSAKWWDVSTAPSPAEAAVALLDLVFAPVNPEHYGQLVRYGQIVPSK"
     aSDomain        complement(2868..3122)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_YIM_RS30130_PKS_KR.1"
                     /evalue="5.00E-08"
                     /label="YIM_RS30130_PKS_KR.1"
                     /locus_tag="YIM_RS30130"
                     /protein_end="91"
                     /protein_start="6"
                     /score="25.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="ALVTGATQGLGLALAEGLARRLTARDVVYLTGRDSGRAAEAAKSL
                     SGAEVRGELLDVADPEAATRFAERLRDRHGGVDIVFGNAV"
     CDS_motif       complement(3060..3119)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_YIM_RS30130_0001"
                     /evalue="5.60E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="YIM_RS30130"
                     /protein_end="27"
                     /protein_start="7"
                     /score="15.8"
                     /tool="antismash"
                     /translation="LVTGATQGLGLALAEGLARR"
     gene            3211..4122
                     /locus_tag="YIM_RS30135"
                     /old_locus_tag="YIM_30360"
     CDS             3211..4122
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020659631.1"
                     /locus_tag="YIM_RS30135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30360"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_153033554.1"
                     /transl_table=11
                     /translation="MTFSDVSLTALRVFREVAERGTFTAAATALGYTQSAVSRQIAALE
                     RSAGAELVERRHDGVRLTAAGHIVVRRAASVLDQVDATARELAGLPDEHATVRLGWFAS
                     AGAALVPRALAALRETHPAITVITREGSTPALARALRAGTLDLALLASAPPFRPPDSET
                     PALRLRTLTERGLCVAVPSTHPLARGDFADVADLAGQRWIAGSGDDRVMGVWPGLDERP
                     EIAHTARDWLAKLHLVAAGCGITTVPASLASVVPSGVRVLPVRGGPAEHRRLMLARLPK
                     PLPEAAGRLAAALRTAAIDAAV"
     gene            complement(4183..4515)
                     /locus_tag="YIM_RS30140"
                     /old_locus_tag="YIM_30365"
     CDS             complement(4183..4515)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005456081.1"
                     /locus_tag="YIM_RS30140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30365"
                     /product="SAV_915 family protein"
                     /protein_id="WP_153033555.1"
                     /transl_table=11
                     /translation="MSENENPDSGAAVEFPSFVFVPCAAHVKDPADAIVEFRRVSDGRL
                     ALMVYSSLDQLKSCCGEQQPWLWTPTPVLEHLKQVQPYDFAVLDVVIPEEHRTIPGKPQ
                     PRHTTA"
     misc_feature    4496..4510
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.19"
                     /tool="antismash"
     misc_feature    complement(4497..4512)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.38"
                     /tool="antismash"
     gene            complement(4538..6019)
                     /locus_tag="YIM_RS30145"
                     /old_locus_tag="YIM_30370"
     CDS             complement(4538..6019)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS30145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_30370"
                     /product="hypothetical protein"
                     /protein_id="WP_153033556.1"
                     /transl_table=11
                     /translation="MTTPSGEGSGAGGTDGGSSGAPATTEAPAPEKPSGSTESSGGTSA
                     ATPESNPTPDKPADDSADKASGSTSEPAPPSDPAGEGADTTANQEQSTAGAPPAGPDSS
                     DDPASGEAAGDDAPAEGSEEDVPGTMPGAEMKEVNNEDTRPRPGDEGFIGPVAPEDRQQ
                     DPEAGSLDSIIQQLQGTKRDAEDAHSEGDRGSRDVVDAWLDPNQDPARDRTGRTLDDTK
                     GVGDSADALGQQVGRTQEQINAALRTIEESDRDAGSVDLLRPLLGAGESDVVNQRTQDM
                     AAAERDRIANLTAEQIRNDPGWEGIEGGAAPASLAGNPEAIASADVLANAGAGVGGWQA
                     AQSAARKADWWSGIASQAREYLPNSDVQRHVSLHGQVGRGEANAHLFSNAGKVANAASK
                     FGGPVLGLPLAGLAIDNDIAAGETPAQAWASNGAGWGAGALTGLAIGASVGGPIGAVLG
                     AIGGAAAGAVASGAVDNLFEHGSVVAPDDYQSPQA"
     gene            complement(6099..6944)
                     /locus_tag="YIM_RS30150"
                     /old_locus_tag="YIM_30375"
     CDS             complement(6099..6944)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (2-127). E-value: 3.1e-12.
                     Score: 38.6. Matches aSDomain:
                     nrpspksdomains_YIM_RS30150_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009946500.1"
                     /locus_tag="YIM_RS30150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30375"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_153033557.1"
                     /sec_met_domain="PF00561 (E-value: 7.6e-09, bitscore: 34.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-15, bitscore:
                     57.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVVFAHGTNSSSYWCSGLIRELTLRGHRAVAVDLPGHGDEAFY
                     PRAYQAPQDLEALATEPSPLAKITIDDYVDRVVEVVRRARRHGPVILAGASQGGVTVSR
                     VGNAIPDELERVVYVAAYCCVDLPNMIAYLETPENSESLLHLIEAVKVADPAVLGVSRL
                     NWRSADPAVFHAVKESLAADFTDEGVSRLLNMLEPDETAAIPATEARGQADTWGRIPRT
                     YVRFTRDRLIPPALQDRFIAEADRLTPDNPTDVRNVEAPHVGPFDRPELVDIFSELAGT
                     "
     aSDomain        complement(6564..6938)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_YIM_RS30150_Abhydrolase_1.1"
                     /evalue="3.10E-12"
                     /label="YIM_RS30150_Abhydrolase_1.1"
                     /locus_tag="YIM_RS30150"
                     /protein_end="127"
                     /protein_start="2"
                     /score="38.6"
                     /tool="antismash"
                     /translation="TVVFAHGTNSSSYWCSGLIRELTLRGHRAVAVDLPGHGDEAFYPR
                     AYQAPQDLEALATEPSPLAKITIDDYVDRVVEVVRRARRHGPVILAGASQGGVTVSRVG
                     NAIPDELERVVYVAAYCCVDL"
     gene            complement(6959..7534)
                     /locus_tag="YIM_RS30155"
                     /old_locus_tag="YIM_30380"
     CDS             complement(6959..7534)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.4"
                     /locus_tag="YIM_RS30155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30380"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_153033558.1"
                     /transl_table=11
                     /translation="MAIDTPYASVRPATEPDLRVAGDVLVDAFMDDPVVCWLHPERSER
                     ARLQAEFYRPLLAHGEVYLAGAGEGAAVWLPLAAGPWHPEPADEEVDPRLRALGQALGD
                     RHPDRAHLYLPCMGVVAGRQGSGLGSALLHDRLSRADADGIAAYLEASSPRSRAFYRRH
                     GFEDSGPPVQVGDSPLLWPMVREPKHTK"
     gene            7649..8545
                     /locus_tag="YIM_RS30160"
                     /old_locus_tag="YIM_30385"
     CDS             7649..8545
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010232196.1"
                     /locus_tag="YIM_RS30160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30385"
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="WP_153033559.1"
                     /transl_table=11
                     /translation="MPSLTEPPYLRIAAEIRARILTGELAAGDRVPSVRQIARRWGVAL
                     ATANRALATLRENGLVEAKVGSGTVVSASAGRKQPEPVPGLNRRHILRTAVEIADVEGL
                     DAVSMRRVAAELGAGPMALYRHVASKDELVRQMADEVFAELELPNPGPDGWRAKLELVA
                     RGQWALCHRHLWLPRAVSFTRPLLAPNMMAQTEWTLRALDGLGLPMAARLREALTLHSL
                     VVTTARSLAEESETELETGVDFGGWWLAQRKRTDELLDSGQFPLLKSIPEETVADLDGL
                     FEYGLARHLDGFAVLLR"
     gene            complement(8547..9329)
                     /locus_tag="YIM_RS30165"
                     /old_locus_tag="YIM_30390"
     CDS             complement(8547..9329)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097775.1"
                     /locus_tag="YIM_RS30165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30390"
                     /product="hypothetical protein"
                     /protein_id="WP_228004097.1"
                     /transl_table=11
                     /translation="MTAEALAVAQKSADAYREAFGDRLTAVYLLGSLAYGGFSAAVSDI
                     DLALVLADSGDGDRETVDGVSESLRERGGLYPKLSVFWASLPALSEGRDDGRFPALDRL
                     ELAEHGRLLIGDEVAASVARPAAEELSLESARFAVGVLSTDEVIAEFHTPRRLLADAVW
                     FTKAVLFPVRFLYSNAKTGGRAATNDEAVEWYLSRMDAPAKPLVQQAARVRAGEPLGGG
                     GFAAELRELYRYYIDDQIGRLTDADLISSFERWRARLS"
     gene            complement(9326..9952)
                     /locus_tag="YIM_RS30170"
                     /old_locus_tag="YIM_30395"
     CDS             complement(9326..9952)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228188.1"
                     /locus_tag="YIM_RS30170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30395"
                     /product="hypothetical protein"
                     /protein_id="WP_153033561.1"
                     /transl_table=11
                     /translation="MSHQDVDRIASHNEQRQQEYASSALIRLLADENTAEPTKKTVLTY
                     LQPWSNAFQRMISARVAFEPDPELRALALEHQEEEIGHDRILARTRAEDTELVWDPVIE
                     SGASWFVDQFAILPSVHRAVLAHLALEAGSLVLSQAGTKAFPDDPYFELHDEADVEHLE
                     MGYRLLRERADWTVDEVITLLDRAWQVIGVVSDRIAECARRDTAT"
     gene            complement(10001..11113)
                     /locus_tag="YIM_RS30175"
                     /old_locus_tag="YIM_30400"
     CDS             complement(10001..11113)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020645939.1"
                     /locus_tag="YIM_RS30175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30400"
                     /product="hypothetical protein"
                     /protein_id="WP_228004098.1"
                     /sec_met_domain="indole_PTase (E-value: 3.5e-54, bitscore:
                     183.3, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVNGSPGLCDQARENGSYPAQGRLYGEFLCGVWATACEALEVPAD
                     QAAWTRRLLGAALPAWAVERIGSTPERPSYVAGDGFPAEMSVNWSGGQPELRVLFDCLD
                     DVQHGHSLISAAAQGNAREGIHRLFTPQSGRPSEAPLWHSVAWRPSSRLVHKTYFGLYD
                     WPFAERYAAVDEAMARLGLAAAWERTRARVENAGGQREIEFFAVDLAGEADARVKIYYR
                     NHGADLAEVNRIAATALRHDEENALAAYRTLAGARADAGEAALSCLAFRSGVDGADECT
                     TYLRLTDLAADDQEAVDRTAALLHREGVDPARFRALAEALVPGSLEDSRGLLELVSYRA
                     SGRRGDLTTYFRLPVFESSAARLLAPVDLG"
     gene            complement(11292..11882)
                     /locus_tag="YIM_RS30180"
                     /old_locus_tag="YIM_30405"
     CDS             complement(11292..11882)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009071593.1"
                     /locus_tag="YIM_RS30180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30405"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_153033562.1"
                     /transl_table=11
                     /translation="MASSSTDGSAADNVPTPVKIIVAGGFGAGKTTMVGSVSEIPPLTT
                     EEVLTEASAGVDDLSGVERKHTTTVALDFGRITISPRHVLYLFGTPGQARFWFMWDDLA
                     RGAIGTIVLVDTRRLETSFAAIDFFERRKIPFIVAVNCFDKAPRYTPDEIREALVVPDR
                     VPIVMCDARDRDSSKLALIRLVKHAMTVLPVPA"
     gene            complement(11863..12234)
                     /locus_tag="YIM_RS30185"
                     /old_locus_tag="YIM_30410"
     CDS             complement(11863..12234)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013228185.1"
                     /locus_tag="YIM_RS30185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30410"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_153033563.1"
                     /transl_table=11
                     /translation="MSGEDGWYDEAAGPLVRPYTITSGRTPGESAKLDLSTQVMTLRQE
                     QEPTGLGPEHMAIVQLCRNPVSIAEIAVYVKIPLGVVRVLCADLIERGLVITRSPTHHP
                     AQAPNLETLQAVLDGLIKY"
     gene            complement(12231..12656)
                     /locus_tag="YIM_RS30190"
                     /old_locus_tag="YIM_30415"
     CDS             complement(12231..12656)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003097762.1"
                     /locus_tag="YIM_RS30190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30415"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_153033564.1"
                     /transl_table=11
                     /translation="MNEYGNAKPDLNWLLDDMVNRVVGAQNAIVLSADGLLIGKSAGMS
                     KDDSDQLSAIASSLQSLAKGVSKQFARGAVLQNMIEMELGYLFVSAAGAGACLAVLAGE
                     NVDVEMIAYEMSRLVKRVGDYLTAAPRETAHALREAT"
     misc_feature    complement(12637..12648)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.46"
                     /tool="antismash"
     gene            complement(12706..15105)
                     /locus_tag="YIM_RS30195"
                     /old_locus_tag="YIM_30420"
     CDS             complement(12706..15105)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015788001.1"
                     /locus_tag="YIM_RS30195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30420"
                     /product="ATP-binding protein"
                     /protein_id="WP_153033565.1"
                     /transl_table=11
                     /translation="MQNKDEQDESDKPYDKSIRKRLTRTVLIPSVTLLVLWTALSSYFF
                     INGLYVRLVAASVREVSIPAATALAAFQQERQTALRYLDNPSAGQAGLQEKQQATDEKL
                     VALQAAFDSTISSAPDEIATKVNGLKSQFEQLPVLRSQINFRSIDRAQVNDYYNGVLDA
                     ASNLFDTQARVVPDAEAAHGGVTATTVFRAGDLMSRETSLVSTAFAAKAFDPDDFVQFT
                     QLSGAYRTQLAQVEPFLDPEVRAKYQALTTSPAWDQLANAEEALVKRGPWAGAQANNLP
                     VSEADWQSAANQVASSLNDLSIQQADKVSAAAIESGDAQLRNAIIGSVLALLASLAAII
                     VAVRVSRSLVDRALMTRLARLRDDALDLARNRLPRIVGRLKSGEPVDLKQELPQLDHGR
                     DEIGQVAEAFNAAQLTAVNAAASEAKARSGVHNVFLGIAHRNQVLVHQQLQILDEMESR
                     EENSTQLASLFQLDHLAARARRTTENLIILGGKQPGRRWRKPVPLLEVLRAAVSETEQY
                     ARVQVEQVADVAIVGVAVADTIHLIAELVDNATSFSPPGSPVEVTSRKVARGVVVDVSD
                     QGLGMKDSVRQWANEMMAEAPEFDAMALRADSSLGLFVVARLAAKLGITVTFDPSRYGG
                     LRATVLIPSQHLAGEEAERNGEAEFTAAPDNAVLASVGAPAPSASAQESSAPTMNTHSS
                     FTGQIPLKRDVKPRPYPARAHTPEAAPTTPPAFTEAKPAAPAEPPPPPADDRPRLPRRE
                     PQQNLVAQLEHEPDDDVQSTVTPGEGTARTLAAFHKGTRRGRDGDS"
     misc_feature    complement(15212..15226)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            15583..17061
                     /locus_tag="YIM_RS30200"
                     /old_locus_tag="YIM_30425"
     CDS             15583..17061
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009950875.1"
                     /locus_tag="YIM_RS30200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30425"
                     /product="SLC13 family permease"
                     /protein_id="WP_153033566.1"
                     /transl_table=11
                     /translation="MLKIAAHRADPAATAAPRVPRWPFGLAAAAVALAALYLFLPDAGS
                     ALPAAGRSTLVVFAGATLFWLFGRNDTYVGFAALLALVFLRVLDADQVFAALGGETVWL
                     LISAFVLAAGISATGLPARAAIALCTRASRVRTLFHLLTAWLVLTAFAIPATSGRAALA
                     LPVFLALARAFTGRPAVVRALALLIPTVILLSAAATLTGAGAHLITVEILAGATGSGIS
                     FGQWLLLGVPIAVLSSHLAAELVLLLMTRRAERKQPVVVDARRLAEESGVPPGPLNVVQ
                     LRALAVLALVVGLWCTEAWHGLSPALVALAGAVLITVPKAGTVALDTALSTVPWSLLLF
                     MVATTALGSALSLSGAAGWLAGVTLGQHTGDAFVVLAVVVGVSAAAHLVLQSRSARSSV
                     LVPLILPVAAVSGLNPAAAAFASTVAAGFCHTLPASAKPVALFSGIDDAPTYRRSDLLR
                     LSVVLGPLLVLLVLLFATAVWPRFGLPLYLQEKK"
     misc_feature    17032..17034
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17058..18254
                     /locus_tag="YIM_RS30205"
                     /old_locus_tag="YIM_30430"
     CDS             17058..18254
                     /EC_number="2.7.1.31"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008887 - glycerate kinase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803645.1"
                     /locus_tag="YIM_RS30205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30430"
                     /product="glycerate kinase"
                     /protein_id="WP_153033567.1"
                     /transl_table=11
                     /translation="MTTPLRLVIAPSGFKESLSADAVAGAIAAGVRRVAPTALLDTVPL
                     VDGGEGSARALAENTGGGLIPVTVTGPVGDPVVAPLALLGGPGPRTAVVEMAAAAGLRL
                     VPADRRDPGRTTTYGVGELIRSALDLGCARILVGCGDSGTCDGGAGALSALGAKITDAD
                     GRAIPFGGYALNDAVSLDTSGLDPRLRDTELVVACNPCNVLTGDRGVATVFGPQKGATP
                     AQVAVLSAAMDRWAALLDGASGKNLRLVPGGGASGGLGAGLAGGLGARLRSRFDVLLDQ
                     FDLNARISTADLVITAEGTIDAQTVRGKVPGEVARLAKRHDVPVIALAGTIGEGADATR
                     GAGIDAFTGILAAPGTLADAIGNAEALLTNATERALRLIMVGTHLPDLAPRCASGLPA"
     gene            18362..19519
                     /locus_tag="YIM_RS30210"
                     /old_locus_tag="YIM_30435"
     CDS             18362..19519
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015801952.1"
                     /locus_tag="YIM_RS30210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30435"
                     /product="metallophosphoesterase"
                     /protein_id="WP_153033568.1"
                     /transl_table=11
                     /translation="MTQTRQPRRPRQRTGRRPGVFAGVVVLALLLLFGVPWATLVLPWP
                     TPVVVAGTVLFGIAAPAFPVLMFLGHGRGRDWAARIADTALGVVWVFFAWSVLSLVARV
                     ALLGVAEPRRSRIIAVLVLVIGVALVGYGVREAMRVPRIRRVEVTLPRLGSGLDGTTVA
                     LLTDTHFGPLDRTRWSRRTAAAVNALKPDIVAHAGDLADGTVEQRRAQVAPLGTITAPL
                     ARVYSTGNHEYFGEAQAWLDHMSSLGWDSLHNRHVVVERGGHRLIVAGIDDATARASGL
                     DGHGAELDRALDGAPEDVPILLLAHQPKQIAETANQVDLQLAGHTHGGQIWPFHYLVRT
                     DQPVLEGLSQHGTTQLYTSRGAGFWGPPLRVFAPSEITLITLRAP"
     gene            complement(19500..20501)
                     /locus_tag="YIM_RS30215"
                     /old_locus_tag="YIM_30440"
     CDS             complement(19500..20501)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020639978.1"
                     /locus_tag="YIM_RS30215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_30440"
                     /product="zinc-binding dehydrogenase"
                     /protein_id="WP_153033569.1"
                     /sec_met_domain="ADH_N (E-value: 4.9e-24, bitscore: 83.4,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 7e-09, bitscore:
                     34.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRAFVLTGPEAYEVREVPSPRAVPGEVVVDVERAGVCGTDVEFFT
                     GEMAYLHQGHSSYPLRLGHEWAGTVTAIGDGVDPGWLGRRVMGDTMLGDRTCRRCLRGL
                     QHVCEHRQEVGIRDGRPGALAERIAVPDWSLHALPDSVDAVLGALVEPGGNALRAARAA
                     DAGPGDRVLVMGPGTIGLLVALFLRAAGAEVHLLGRTASSLDFARGLGFEHTWGEVPDL
                     PFDAVVDAANAEHLPALALDRVEPGGRIVYIGIAGRPSRIDTRALVLKDVTAVGILSAS
                     PGLADTIAAYAEGTVDPRPLVAATVGLDEVGAVLAGKYPGPKVQVDPRAPAG"
ORIGIN
        1 cccggccggg ttggaggacg gcaactacgt cacgccgacg gtgttcgccg atgtcgacaa
       61 ctcgatgcgc atcgcgcagg aggagatctt cgggccggtg ctggcggtga tcccctacga
      121 caccgaggac gacgcggtgc gcatcgccaa cgagtcggag tacgggcttt ccggcggtgt
      181 ctggtcctcc gacgaagcac acgcgctcgc cgtcgcgcga cggatgcgga ccggcaccgt
      241 caccgtcaac ggcgcctcga tcggcttcga aggaccgttc ggcggtttca agtccagcgg
      301 catcggccgc gagtacggcg cggtcgggct cggccagtac atcgaataca aaacggtgac
      361 catgcagccc cagcagtagg ccgattcatc cccgcctgcc ctcgaatggg cgctgcgcca
      421 aggcaaaccg gttcctagcg tggatggcca gggggtgcgc cgtggtgacc gtgctggtgg
      481 cgatcggcgt gctctggctg ccggggctgg cggtggccgc ggcggtgcgg cgcaccggct
      541 gggcggtgct cggggcggcc ccggctctca ccttcgggct ggcgggactg gccggaccgc
      601 tgttcagcct gctcggcgtg ccgtggcggt ggtggagctt cctgctcttc ctggccgtgg
      661 tggtgacagt ggccgcgatc gcccggccgt ggcttcgcgg gaacaccaac gccgagccgg
      721 aaacctggcg gcgcgacggt ttcctcacca tcgggcccgc tgcggtggtc gcggcggcga
      781 tcggcgccgt ggtcgtggcg ctgggcatgc gcggcggcct ggacgcggtg tcccaggtct
      841 gggacatgag cttccacggc aacgcgatcc ggcacatcac cgactccggc gacccggcac
      901 cggccggact ggccgcgatc gctgaggacc acccggattt cttctatccc aacgggttcc
      961 acctgatcgg ctcgctcgcg cacggcatca ccgggcagcc accgccgacc gtgctcaacg
     1021 gcctggtcat cgcggtggcc acgctgctgg taccgctggg caccgccgcg ctcgccgccg
     1081 ggctgggcct gcgtgccggc gcggtggccg cggccgtggt ggtcagcacc accttcgcca
     1141 acctgcccta cctgctgtgg agctacggcg ggctctatcc ctacgcgctc gcgctgtgcc
     1201 tggtcgggcc cgcgctggcg ctggcggtgc gctggctcac cagcggtgac accggcgtgc
     1261 tgccgatggc cgtgctcgcc gcgaacgggg tgctggtggt gcacccgagc gcggccgtgg
     1321 tcctcgccgt gttcggcgtg ctggtgctgc tcctgcggga ccggcgcgaa tttccgctcg
     1381 actgggccag attgggcgtg ctgctcggac tctgcgcgct ggttctgctg ccgttgctgg
     1441 acggcctgct gcgcgtgacc ccgcgggtcg cctccttcca gccgttctgg gcggcgagca
     1501 gcgacgccgg gaccgcggtg ctccgggtgg tcaccctcgg cggggtggtt ccgcagccgg
     1561 gcgaggcggc accaccggcc cagtgggtgc tggccgtgct ggtgttcggc ggcctgctgc
     1621 tgttcctgcg cgtaccggcc tggcggtggg ccaccgcggc ggcgctggtg ttcgccgcgc
     1681 tgtacgtgct gtcggtgtcc accgaccacc cggtgaccag gtacctggcc gcgccgtggt
     1741 ggaacgacag cttccggctg gtcgcggtgc ttccggtggt gggcgcggtc gccgccggtc
     1801 acctgctcga cgaagtgcgc cgccgtctcg gcgactggcg cgctggggtc ctgatcctgg
     1861 ccggctacct gggcgcgacg ggcgggtacg ccgtcgcgaa cggggaccgc gtgcgcgaga
     1921 tgtaccggcc cggcccggtc actccggagg tggcggccgg gctgcggcgg ctcaccgaac
     1981 tcgtgccgcc gggcaccggc gtgatgaacg acaacggcga cggctccacc tgggcctacg
     2041 gcctggtcgg ccgccggacc gtggtgccct acttcggcaa ctacccaccc ggctcggacc
     2101 ggtgggtgct gctggagaaa ttcgacgagg tggccaccga tcccggggtc cgggaactcg
     2161 tgcgccggta cgacatcggg tacgccgtgg tcgccacgcc catgctctac ggcaaggagc
     2221 gcacaccggg cctgcgtgaa ctggaccagc ccccgttccg gctggtctac gagaatcccg
     2281 ggttccgcat ctaccagctc accggctgag cgctacttcg agggcacgat ctgtccatat
     2341 cggacaagct gtccgtagtg ctcggggttc accggtgcga aaacgaggtc cagcagggcg
     2401 acggcggctt cggccggact gggcgcggtg ctgacgtccc accacttcgc cgaggtcggc
     2461 gtgttgatca ttcccgggca gaccgcggcg agcaggatgc cgcgggcgag gtcggactca
     2521 cgacgttgtg acgccagcgc ccgcaccgcc gcgacctggg cgatcttcga cgggatgttg
     2581 acaaaccccg gccaggcgcc ggatcgggcg ctgccgtcgg cgaccgcgtc gcgccaggcc
     2641 accacctgct tgtccacctg gtccagtgtg gacagatcgt cgaagcgccg gtgcagcacc
     2701 ggtgcgagct ggtgcagggt gcccagtgag ctggcgacca cgatgagcct gccgttgtcc
     2761 cgcaccagtg gcgcgaacgc ccgcagcagc cgggtggtgc cgaagttgtt cacctgggtg
     2821 tagggatcga tgatctcgcg cggatcgtcc tcgggcccga cgcgcatgac cgcgttgccg
     2881 aagacgatgt ccacgccgcc gtgccgatcg cgcagccgct cggcgaaccg ggtggcagcc
     2941 tcgggatcgg ccacgtcgag cagttcaccc cggacctcgg cgccggacag gcttttcgcg
     3001 gcttcggccg cgcgtccgga gtcgcgcccg gtgaggtaga cgacgtcccg tgcggtcagc
     3061 cgccgcgcca gcccttcggc cagcgccagc cccagtccct gggtcgcccc ggtgaccagt
     3121 gcgattcgtg aagtggtcat gacgccacgc taagcgcggt ccggccatgc cgacagcgaa
     3181 agtccggcac acctggtatg cgtaagtgtc atgaccttct ccgacgtctc gctcaccgcg
     3241 ctgcgggtgt tccgcgaagt ggccgagcgc ggcacgttca ccgccgcggc caccgcgctc
     3301 ggttacaccc agtccgccgt ctcccgtcag atcgccgcgc tggaacggtc ggcgggcgcc
     3361 gagctggtcg agcggcggca cgacggggtg cggctcaccg cggccgggca catcgtggtg
     3421 cgccgcgccg cttccgtgct cgaccaggtc gacgccaccg ccagggagct ggccggactg
     3481 cccgacgaac acgccacggt ccgcctcggc tggttcgcca gcgccggggc cgcactggtg
     3541 ccgcgagcgc tggccgcgtt gcgtgaaacg cacccggcca tcacggtgat cacccgcgag
     3601 ggcagcaccc cggcgctcgc gcgggccctg cgggcgggca cgctggatct ggccctgctg
     3661 gcgtcggcac cgccgttccg cccgccggac agcgaaacgc cggccctgcg gctgcggacg
     3721 ctgaccgagc gcggcctgtg cgtggccgtg ccgtccacac acccgctcgc gcgtggtgac
     3781 ttcgccgacg tcgcggacct ggccgggcag cgctggatcg cgggttccgg cgacgaccgg
     3841 gtgatgggcg tgtggcccgg cttggacgaa cggcccgaga tcgcgcacac cgcacgggac
     3901 tggctggcca aactgcacct cgtggcggcg ggttgcggga tcaccaccgt gcccgcgtca
     3961 ctggcgtccg tcgtgccctc cggggtccgc gtgctaccgg tccgcggcgg cccggccgag
     4021 caccgacgcc tgatgctcgc ccgactcccg aaacccctgc cagaggcggc cggccgcctc
     4081 gccgccgccc tgcgaaccgc agctatcgac gctgctgtct agcactgcgg cggcggtccg
     4141 gtgaatgggt ggcctcgatg ttcgaggccc ttcctccctg gctcaggctg tcgtatgccg
     4201 cggttgcggt ttcccgggaa tggtccggtg ttcctctggt atgacgacgt cgagaaccgc
     4261 gaagtcatac ggttgcactt gcttgaggtg ttcgagcacg ggcgtcggtg tccacagcca
     4321 gggctgctgc tctccgcagc acgatttcag ctggtcgagg gacgagtaca ccatcagcgc
     4381 cagccgaccg tcgctcacgc ggcggaactc gacgatcgcg tcggcgggat ccttgacatg
     4441 cgcggcacag ggcacaaaaa cgaaggaagg aaattcgacc gctgccccgg aatccggatt
     4501 ttcgttctca ctcattgcta cacttcctcg tgagcgatca tgcctgcggg ctctgatagt
     4561 cgtcaggtgc caccacggaa ccgtgctcga acaaattgtc gaccgcgcca gaggccaccg
     4621 cgcccgccgc ggcgccgccg atcgcgccca gcacggcgcc gatcgggccg ccgacggacg
     4681 caccgatggc gagccccgtc agcgcacccg ctccccagcc ggccccgttc gacgcccatg
     4741 cctgtgccgg cgtttcacca gccgcgatat cgttgtcgat ggcaagaccg gcaagaggca
     4801 gtccgagcac gggcccaccg aatttgcttg cggcgttggc gactttgccg gcattcgaga
     4861 aaaggtgcgc gttcgcctct ccacgcccca cctggccgtg cagggagaca tggcgttgta
     4921 cgtccgaatt gggcaggtac tccctggcct gggaggcgat ccccgaccac caatcagctt
     4981 tgcgcgccgc tgattgcgct gcttgccagc caccgacgcc ggcacccgcg ttcgccagaa
     5041 cgtcggcgct ggcaatggct tcgggattac cagccaacga cgcgggggca gcgcctcctt
     5101 cgataccttc ccagccggga tcgttcctga tctgctccgc cgtcagattg gcgatccggt
     5161 cacgttcggc cgcggccatg tcctgggtcc gctgattcac gacgtcgctt tcaccagcac
     5221 cgagaagcgg ccggagaagg tcgaccgatc ccgcgtcccg atcgctctct tcgatcgttc
     5281 gcaaggccgc gttgatctgc tcctgagtgc ggccgacctg ttgccccagc gcgtcggctg
     5341 aatcaccgac accttttgtg tcatcgagcg ttcggccggt cctgtcccgc gccgggtcct
     5401 gattgggatc cagccaggcg tcgacaacat cgcggctgcc ccggtcgccc tcggaatgcg
     5461 cgtcctcggc gtcgcgcttg gtgccctgca actgctgaat gatggaatcg agagaccccg
     5521 cttcgggatc ttgctgccgg tcttcgggcg cgacggggcc gatgaaccct tcgtcgccag
     5581 ggcgaggtcg cgtgtcctcg ttgttcacct ccttcatttc cgccccgggc atggtccccg
     5641 gaacatcctc ttcgctcccc tcggccggtg cgtcgtcgcc ggcggcctcg cccgaagcgg
     5701 ggtcgtcaga cgaatcaggg ccggccgggg gtgcgccggc agtgctctgt tcctggttcg
     5761 ccgtcgtgtc cgcaccctca ccggcggggt cggaaggcgg cgccggttcc gacgtggatc
     5821 ccgatgcctt gtccgccgag tcatcggcgg gtttgtccgg ggtcggattg ctctccggcg
     5881 tcgctgccga cgtgcctccc gacgactcgg tggagcccga cggcttctcc ggcgccgggg
     5941 cttccgtcgt ggccggcgcg cccgaggagc cgccgtcggt gccgcccgcg cccgaaccct
     6001 cgccagaagg tgtcgtcatc tcgtactccc ggagaccaaa ggatgcgttg cagtcgcact
     6061 tcagtctccg ccggcaccgt gtcgcgctgt gcggtttgtc aggttccggc cagctcgctg
     6121 aagatgtcca ccagttccgg ccggtcgaac gggccgacgt gtggtgcctc gacgttccgc
     6181 acgtcggtgg ggttgtccgg ggtgaggcgg tcggcctcgg cgatgaaccg gtcctgcaag
     6241 gccggcggga tcagccggtc gcgggtgaat cgcacgtagg tccgggggat ccggccccag
     6301 gtatcggcct gaccacgcgc ctcggtcgcc gggatggcgg cggtttcgtc cggctccagc
     6361 atgttgagca gcctgctgac accttcgtcg gtgaagtcgg cggccaggct ttccttgacc
     6421 gcgtggaaaa ccgcggggtc ggcggagcgc cagttgagcc ggctcacccc gaggaccgcc
     6481 gggtcggcga ccttgaccgc ctcgatcagg tggagcaggc tttcgctgtt ctccggggtt
     6541 tccaggtagg cgatcatgtt cggcaagtcg acgcagcagt acgccgcgac gtagacgacg
     6601 cgctccagct cgtcgggaat ggcgttgccc acccggctca ccgtgacccc gccctgactg
     6661 gcaccggcga ggatcaccgg accgtgccgc cgggcccggc gcaccacctc gaccacgcgg
     6721 tccacgtagt cgtcgatggt gatcttcgcc agcggtgagg gctcggtcgc cagggcttcg
     6781 agatcctgcg gcgcctggta ggcacgcggg tagaacgcct cgtcaccgtg gccgggcagg
     6841 tcgacggcga cggcgcggtg gccgcgcagg gtgagttcgc ggatcagccc ggagcaccag
     6901 tacgacgagg aattggtgcc gtgcgcgaat accactgtgg acatttgaac gttctccttc
     6961 acttggtgtg cttcggttcg cggaccatcg gccacaggag cgggctgtcc ccgacctgga
     7021 ccggcgggcc cgagtcctcg aatccgtgcc gccggtagaa cgcgcggctc cgcggcgaac
     7081 tcgcttcgag ataggcggcg atgccgtcgg cgtccgcccg cgaaagccgg tcgtgcagca
     7141 acgccgaacc gagcccgctc ccctgacgcc cggcgaccac tcccatacac ggcaggtaga
     7201 ggtgcgcccg atcgggatgc cggtccccca gcgcctgccc cagcgcgcgc aggcgcggat
     7261 cgacctcctc atcggccggc tcggggtgcc acgggcccgc cgccaacggc aaccacaccg
     7321 ccgcgccttc tccggcaccg gccaggtaga cctcgccatg cgcgagcagc ggccggtaga
     7381 actccgcttg gaggcgggcg cgctcactcc gctccggatg gagccagcag acgacgggat
     7441 cgtccatgaa cgcgtcgacg agcacgtcgc ccgccacccg caggtccggc tcggtggccg
     7501 gtcgaacgga tgcgtacggt gtatcgattg ccatgcgtac acggtatcgg cgaagctggc
     7561 cgacgcgccg ctttccgcgg cacacaagcg aaacaagtgt tcaggtgatc tagtacactc
     7621 agctcggcga agacgaagga gacctggaat gccgtcgttg accgaaccgc cctacctgcg
     7681 gatcgccgcg gagatccgcg cacgcattct caccggcgag ctggcggccg gtgatcgcgt
     7741 gccgtccgtg cggcagatcg cgcgccggtg gggtgtcgcg ctggcgacgg cgaaccgggc
     7801 gctggccacc ctccgcgaaa acgggctcgt ggaagcgaaa gtcggctcgg gcacggtggt
     7861 gagcgcgtcg gccgggcgaa agcagccgga gccggtaccc gggctgaacc gccgccacat
     7921 cctgcgcacc gccgtcgaaa tcgccgatgt cgaaggcctc gacgcggtgt cgatgcgccg
     7981 ggtcgcggcc gaactcggtg ccgggccgat ggcgctgtac cggcacgtgg cgagcaagga
     8041 cgagctggtc cggcagatgg ccgacgaggt tttcgccgaa ctcgaactgc ccaaccccgg
     8101 cccggacggc tggcgcgcca agctcgaact cgtcgcccgc ggccagtggg cgctgtgcca
     8161 tcgccacctc tggctgccca gggcggtttc gttcacccgc ccgctgctcg cgcccaacat
     8221 gatggcgcag acggaatgga cactgcgcgc gctcgacggg ctcggcctgc cgatggccgc
     8281 ccggctccgt gaggcgctga ccctgcattc actggtcgtc accacggcga ggtcgctggc
     8341 cgaggaatcc gaaaccgagc tggagaccgg cgtggacttc ggcgggtggt ggctggcgca
     8401 acgcaagcgc accgacgaac tgctcgacag cggtcagttc ccgctgctga aatcgattcc
     8461 ggaggagacg gtggcggacc tggacggcct gttcgaatac ggcctggccc gccacctcga
     8521 cggttttgcc gtgctgctcc ggtagttcag ctcaaccggg cccgccaccg ctcgaacgag
     8581 gaaatcaggt ccgcgtccgt caaccggccg atctggtcat cgatgtagta ccggtacaac
     8641 tcccgcagct cggccgcgaa acccccgccg cccaacggtt ctccggctcg aacccgcgcc
     8701 gcctgctgga ccagcggctt cgccggagcg tccatacgcg acagatacca ctcgacggct
     8761 tcgtcgttcg tcgccgcgcg cccgcccgtt ttcgcgttgc tgtaaagaaa acgcaccggg
     8821 aacaacacgg ccttcgtgaa ccacaccgcg tcggccagca accggcgcgg ggtgtggaac
     8881 tccgcgatca cctcgtccgt ggacagcaca ccgaccgcga accgggcgct ctccagcgac
     8941 agttcctccg ccgccgggcg cgccaccgaa gcggccacct cgtcaccgat cagcaagcga
     9001 ccgtgctcgg ccagctccaa ccggtccaag gcggggaacc gcccgtcgtc gcggccttcg
     9061 ctcaacgcgg gcaacgacgc ccagaacacg gacagtttcg ggtaaagccc tccgcgctcg
     9121 cgcaacgact ccgaaacccc gtcaacggtt tcccggtcac catcaccgga atcggccagc
     9181 accagagcca ggtcgatatc gctgaccgcc gccgaaaagc cgccgtacgc gagacttccc
     9241 agcaggtaca cggcggtcag ccgatccccg aaggcttccc gataagcgtc ggcgcttttc
     9301 tgggcgaccg ccaaagcttc cgcggtcacg tcgcggtgtc ccggcgagcg cactcggcga
     9361 tgcggtcgga caccacgccg atgacctgcc acgcccggtc cagcagggtg atcacctcgt
     9421 ccacggtcca gtcggcacgc tcacgaagca ggcggtaccc catctccagg tgctccacgt
     9481 cggcctcgtc gtgcagttcg aagtacgggt cgtccgggaa cgccttcgtc ccggcctggc
     9541 tcagcaccaa gctgcccgct tcgagcgcga ggtgcgccag caccgcgcgg tgcacgctcg
     9601 gcaggatggc gaactggtcg acgaaccacg acgcgcccga ctcgatcacc ggatcccaca
     9661 ccagttccgt gtcctccgcc cgcgtcctgg ccaggatccg gtcgtgcccg atctcctctt
     9721 cctggtgctc cagcgcgagc gcgcgcagtt ccgggtcggg ctcgaaggcg acccgggcgc
     9781 tgatcatccg ctggaaggcg ttcgaccagg gctgcaggta ggtgagcacc gtctttttgg
     9841 tcggctccgc ggtgttctcg tcggccagca ggcggatcag cgccgacgag gcgtactcct
     9901 gttgccgctg ctcgttgtgg ctggcgatgc ggtccacatc ctggtggctc acggcagact
     9961 ccttccggtg gcggtaagca tgatcatctt cccggtgccg ctacccgaga tcaaccggcg
    10021 cgagcaggcg ggcggcggag gactcgaaca ccgggagccg gaagtacgtg gtgaggtcac
    10081 cacgtcgccc ggatgcccgg tagctgacca gttccagcag gcctcggctg tcctcgaggg
    10141 agccgggcac caatgcctcg gcgagcgcgc ggaaccgggc gggatccacg ccttcgcggt
    10201 gcagcagggc ggcggtgcgg tccaccgcct cctggtcgtc ggcggccagg tcggtaagcc
    10261 ggagataggt ggtgcactcg tcggcaccgt ccacaccgga ccggaaagcg agacagctca
    10321 acgccgcctc accggcgtcg gcgcgggcgc cggcgagggt ccggtacgcg gccagcgcgt
    10381 tctcctcgtc gtggcgcagg gccgtcgccg cgatccggtt cacctcggcg aggtcggcgc
    10441 cgtggttgcg gtagtagatc ttcaccctgg catcggcttc cccggccaga tccaccgcga
    10501 agaactcgat ttccctttgc ccgccggcgt tctccaccct ggcgcgggtg cgttcccacg
    10561 cggcggccag gcccagccgg gccatcgcct cgtccaccgc cgcgtaccgc tcggcgaagg
    10621 gccagtcgta caacccgaag taggtcttgt gcaccagccg cgaggacggg cgccaggcga
    10681 ccgagtgcca caacggcgcc tcggacggcc tgcccgactg cggggtgaac aaccggtgaa
    10741 tgccttcgcg ggcattcccc tgtgccgcgg cggaaatcag gctgtgcccg tgttgcacat
    10801 cgtccaagca gtcgaacaac acccgcagct ccggctgccc gcccgaccag ttgaccgaca
    10861 tctcggccgg gaacccgtct cccgcaacgt aggacggccg ttccggagtg gacccgatcc
    10921 gctcgacggc ccacgcgggc agcgcggcac cgagcagcct ccttgtccac gccgcctggt
    10981 ccgccgggac ttcgagcgcc tcgcacgccg tcgcccacac tccacacagg aactcgccgt
    11041 acaaccggcc ctgtgctgga tagctgccgt tttcccttgc ctgatcgcac aaccccggcg
    11101 agccattgac cacgcgccaa agagtagcag tcaggtgaga attcaactga tcaactgcac
    11161 ccggctggtc caaccaattg cgccaagtgg gttgacaaca ggacatcccc tgccgcaccg
    11221 acaccaagcg ttaccgcgca ccgctgcgaa atccaggtga acccatcaca cttcccttgt
    11281 caggcaacag atcaggctgg tactggcaac accgtcatcg cgtgcttcac caggcggatc
    11341 aacgcgagtt tgctcgaatc gcggtcgcgt gcgtcacaca tgacgatcgg caccctgtcc
    11401 ggcaccacaa gggcttcgcg gatctcgtcc ggtgtgtacc gtggcgcctt gtcgaagcag
    11461 ttcaccgcca cgatgaacgg gatcttccgc cgctcgaaga agtcgattgc ggcgaagctg
    11521 gtctccaggc gccgggtgtc gaccagcacg atggtgccga tcgccccgcg cgccaggtcg
    11581 tcccacatga accagaaccg cgcctgcccc ggggtgccga acaggtacag cacgtgccgc
    11641 ggcgagatgg tgatccggcc gaagtcgagc gcgaccgtgg tggtgtgctt gcgctccacc
    11701 ccggacaggt cgtccacccc ggcgctcgcc tcggtgagca cctcctcggt ggtcagcggc
    11761 gggatttcgc tgaccgagcc gaccatggtg gtcttcccgg cgccgaaccc gccggcgacg
    11821 atgatcttga ccggcgtcgg gacgttgtcc gccgccgagc cgtcagtact tgatgaggcc
    11881 atcgagaacc gcctggagag tttcgaggtt cggcgcctgc gccgggtggt gggtggggga
    11941 acgggtgatc acgagcccgc gctcgatcag gtcggcgcac agcacccgca ccaccccgag
    12001 cgggatcttc acgtagaccg cgatctcggc gatggacacg ggattgcggc acaactgcac
    12061 gatcgccatg tgctccgggc cgagtccggt gggttcctgt tcctgccgca gtgtcatcac
    12121 ctgcgtggaa aggtccagtt tggcgctttc gccgggagtg cggccgctgg tgatcgtgta
    12181 cggccggacc agtggcccgg ccgcctcgtc gtaccagccg tcttccccgc tcacgtggcc
    12241 tctcgcagtg cgtgcgcggt ttcgcgggga gcggcggtga ggtagtcgcc gacgcgcttg
    12301 accagcctgc tcatctcgta ggcgatcatc tccacgtcga cgttctcccc cgccagcacg
    12361 gcgaggcagg cacccgcgcc ggcggccgag acgaacaggt acccgagttc catctcgatc
    12421 atgttctgca gcaccgcacc gcgggcgaac tgcttgctca cccccttggc caggctctgc
    12481 aggctggagg cgatggcgga gagctggtcc gagtcgtcct tgctcatccc ggcggacttg
    12541 ccgatgagca gaccgtcggc ggacagcacg atggcgttct gcgcgccgac gacccggttc
    12601 accatgtcgt cgagcagcca gttgagatcg ggtttggcgt tcccgtactc gttcatgcgg
    12661 atagaccttg actttcctaa gtggactttc gtgtgctgtc gctgactacg aatcgccgtc
    12721 gcggccgcgg cgggtgccct tgtggaacgc ggcgagggtg cgcgcggtgc cctcgcccgg
    12781 cgtcaccgtg ctctggacgt cgtcgtccgg ttcgtgctcg agctgggcga ccaggttctg
    12841 ctgcggttcg cgccgcggca gccgcggccg gtcgtcggcg ggcgggggcg gcggctcggc
    12901 gggagccgcg ggcttcgcct cggtgaacgc cggcggggtg gtgggtgcgg cttcgggggt
    12961 gtgcgcgcgt gccgggtacg gcctcggctt gacatctcgc ttcagcggga tctggccggt
    13021 gaacgagctg tgcgtgttca tggtcggggc ggagctttcc tgtgccgatg ccgatggcgc
    13081 cggggcgccc actgacgcga ggaccgcgtt gtccggcgcg gcggtgaact ccgcctcgcc
    13141 gttgcgctcc gcctcctccc cggccaggtg ctggctcggg atgagcacgg tggcgcggag
    13201 gccgccgtac cgggacggat cgaaggtgac ggtgatgccg agcttggccg ccagccgcgc
    13261 gaccacgaac aagccgaggc tggagtcggc ccgcagcgcc atcgcgtcga actcgggcgc
    13321 ctcggccatc atctcgttgg cccactggcg aacgctgtcc ttcatgccca gcccctggtc
    13381 cgacacgtcc accaccaccc cgcgggcgac cttgcggctg gtcacctcga ccggcgaacc
    13441 gggcggggag aacgaagtcg cgttgtcgac cagctcggcg atcaggtgga tggtgtcggc
    13501 caccgcgaca ccgacgatgg ccacgtcggc gacctgctcg acctggaccc gcgcgtactg
    13561 ctcggtttcc gaaaccgccg cgcgcagcac ttccagcagt ggcactggct tccgccagcg
    13621 gcggcccggc tgcttgccac cgaggatgat caggttctcg gtggtgcggc gggcacgggc
    13681 ggcgaggtgg tcgagctgga acagcgaggc cagctgcgtg gagttctcct cgcggctttc
    13741 catctcgtcc aggatctgca gttgctggtg gaccagcacc tggttgcggt gggcgatgcc
    13801 gaggaacacg ttgtgcacac cgctgcgcgc cttggcctcg ctcgccgccg cgttgaccgc
    13861 ggtgagctgg gcggcgttga acgcctcggc cacctggccg atctcgtcgc ggccgtggtc
    13921 gagctgcggg agttcctgtt tcaggtcaac gggttcaccg ctcttgagcc ggccgacgat
    13981 gcggggcagg cggttgcggg cgaggtcgag cgcgtcgtcg cgcaggcgcg cgagacgggt
    14041 catcagcgcg cggtcgacga gcgagcgcga cacccgcacc gcgacgatga tcgccgcgag
    14101 cgaggccagc agcgccagga cactgccgat gatggcgttg cgcagctggg cgtcgccgga
    14161 ctcgatggcg gccgcggaaa ccttgtccgc ctgctggatg gacagatcgt tgaggctgct
    14221 ggcgacctgg ttcgccgcgc tctgccagtc ggcttcgctg accggcaggt tgttcgcctg
    14281 cgccccggcc cacgggccgc gcttgaccag cgcctcctcc gcgttcgcca gctggtccca
    14341 cgccgggctc gtggtcaggg cctggtactt cgcgcggact tccgggtcga gaaatggttc
    14401 gacctgtgcc agctgcgtgc ggtaggcacc ggagagctgg gtgaactgga cgaagtcgtc
    14461 ggggtcgaac gccttggccg cgaacgcggt ggacaccagc gaggtctcgc gcgacatcag
    14521 gtcgccggcg cggaagacgg tggtcgcggt gaccccgccg tgcgcggctt cggcatcggg
    14581 caccacgcgg gcctgggtgt cgaacaggtt ggacgccgcg tccagcacgc cgttgtagta
    14641 gtcgttgacc tgcgcccggt cgatgctgcg gaagttgatc tgcgagcgca gcaccggaag
    14701 ctgctcgaac tggctcttca gcccgttgac cttggtggcg atctcgtcgg gcgcgctgga
    14761 gatggtcgag tcgaacgcgg cctgcaacgc gaccagcttc tcgtcggtgg cctgctgctt
    14821 ctcctgcagc cccgcctgcc cggcggacgg attgtccagg taccgcaagg cggtctggcg
    14881 ttcctgctgg aaggcggcca gcgcggtggc ggccggaatg gacacctcgc gcaccgacgc
    14941 ggcgaccagc cgcacgtaga gaccgttgat gaagaagtag gaggacaacg cggtccagag
    15001 caccagcagg gtcacgctgg ggatgagaac ggtcctggtc agccgcttcc ggatggactt
    15061 gtcatacggc ttgtccgatt catcttgttc atctttgttc tgcacggggg ttcacgaact
    15121 cctgagtgac agtcggcgaa aaacgtgggg agatctggca gaggaagcag aaccgacgac
    15181 ggaaccgttg ggaccacagg gacccgggcc catcgccacc agtgctcgcc tcaccctccg
    15241 tgttgccgcg gaacagatca gggtccgttt tttaccatgt ctcacccgaa cgcggtgcta
    15301 cccgcccacc cgactgtgcg ctgcgtcccg aagatcaact actggtgact gtgcgcaccc
    15361 ggtcgactac tggcgtttcg ccaggtacga gcgtcagccg ccgaacaccg tccagcggac
    15421 tgggccgaac gggtgaacat caaattttct cggcacccgg acctacgtcc gtaactcgtg
    15481 tgcgtcccca gtggactccc tggcggacaa cggaacactc cgatgaggat tcactcatcg
    15541 gcgtttcacc ggtcgttcag cgtccggcca cattctcggc ccatgctcaa gatcgcggcg
    15601 caccgcgccg atccggccgc gaccgcggcg ccacgcgtgc cgcgctggcc gttcgggctg
    15661 gccgccgccg cggtggcgct ggccgcgctg taccttttcc tgccggacgc cggatccgca
    15721 ctgcccgcgg ccggccggag cacattggtc gtgttcgccg gagccacgct tttctggctg
    15781 ttcggccgga acgacaccta tgtcggtttc gccgccttgc tggcactggt cttcctgcgg
    15841 gtgctggacg ccgaccaggt gttcgccgcg ctgggcggtg agacggtgtg gctgctgatc
    15901 tcggcttttg tgctggcggc ggggatttcc gccaccgggt tgcccgccag ggcggcgatc
    15961 gccttgtgca ccagggcttc ccgggtcaga acgctgttcc acctgctcac cgcgtggctg
    16021 gtgctcaccg ccttcgccat tcccgccacc tccggccgcg cggcactggc cctgccggtg
    16081 ttcctcgcgc tggcacgggc tttcaccggc cgcccggccg tggttcgcgc gctcgccctg
    16141 ctcatcccga cggtgatcct gctgtccgcg gcggccacgc tgaccggcgc cggagcgcac
    16201 ctgatcaccg tggagatcct cgccggggcc accggttccg gaatctcgtt tggacagtgg
    16261 ctgctgctcg gtgtgccgat cgcggtgctg agcagccatc tcgccgccga actggtgctg
    16321 ctgctgatga cccggcgggc cgagcggaag cagccggtcg tggtggacgc ccggcgcctc
    16381 gccgaagagt ccggcgtgcc accgggaccg ttgaatgtgg tgcaactccg cgctttggcg
    16441 gtgctcgcgc tggtggtcgg gctgtggtgc accgaagcct ggcacgggct ttccccggcg
    16501 ctcgtggcgc tggccggggc ggtgctgatc accgtgccga aggcgggcac ggtggcgctc
    16561 gacaccgcgc tgtccacggt tccgtggtcg ctgctgctgt tcatggtggc caccaccgcg
    16621 ctcggttccg cgctgagcct gtccggcgct gcgggctggc tggccggggt gacgctcggg
    16681 cagcacaccg gcgacgcgtt cgtggtgctc gcggtggtcg tgggcgtcag cgcggccgcg
    16741 cacctggtgt tgcagtcgcg ttcggcccgt tcttcggtgc tggtgccgct gatcctgccg
    16801 gtggccgcgg tttccgggct caacccggcc gccgcggcgt tcgcctcgac ggtggcggcc
    16861 gggttctgcc acacgctgcc cgcgtcggcc aagcccgtcg cgctgttcag cgggatcgac
    16921 gacgcgccca cctaccgccg aagcgatctg ctgcggcttt cggtggtgct cggcccgctc
    16981 ctcgtactgc tcgtcctgtt gttcgccacg gccgtctggc cgcggttcgg tttaccgctc
    17041 tacctccagg agaaaaaatg accacgccac tgcgtctggt gatcgccccc agcgggttca
    17101 aggagtccct gtccgccgac gcggtcgccg gggccatcgc ggccggggtc cggcgcgtgg
    17161 cgcccaccgc gctgctggac accgttccgc tcgtcgacgg cggtgagggc tcggcccgcg
    17221 cgctcgccga gaacaccggc ggggggctga taccggtgac ggtgaccggt ccggtcgggg
    17281 atccggtggt cgcgccgctg gcgctgctgg gcggtcccgg gccgcggacc gcggtggtcg
    17341 agatggcggc cgccgccggg ttgcgcctgg tgcccgccga ccgccgggac ccgggccgca
    17401 ccacgaccta cggggtgggt gaactgatcc ggtccgcttt ggacctcggc tgcgccagaa
    17461 tcctcgtcgg ctgcggtgac tccggtacct gcgacggcgg cgcgggcgcg ctcagcgcgc
    17521 tgggcgcgaa gatcaccgat gcggacggcc gagcgatccc cttcggcggt tacgcgctca
    17581 acgacgcggt gtcgctggac acgagcgggc tggacccgcg gctgcgcgac accgaactgg
    17641 tcgtcgcgtg caacccgtgc aacgtgctca ccggtgaccg cggtgtcgcc accgtcttcg
    17701 gtccgcagaa gggggccacc ccggcgcagg tggccgtcct gtcggcggcg atggaccgct
    17761 gggccgcgct gctcgacggc gccagcggga agaacctgcg gctggtcccc ggcggcgggg
    17821 cgtccggtgg gctcggcgcc ggtctcgcgg gtggcctcgg cgcgcggctg cgctcccggt
    17881 tcgacgtgct gctcgaccag ttcgacctga acgcccggat cagcaccgcg gacctggtga
    17941 tcaccgccga aggcaccatc gacgcccaga ccgtccgcgg caaggtgccc ggtgaggtgg
    18001 ccaggctcgc caagcgccac gacgtcccgg tcatcgcgct cgccggcacc atcggcgagg
    18061 gcgccgacgc cacccgcggc gccggcatcg acgccttcac cggcattctc gccgcccccg
    18121 gcaccctggc cgacgccatc ggcaacgccg aggccctgct caccaacgcc accgaacgcg
    18181 ccctgcggct gatcatggtc ggcacgcacc tgccggacct ggcgccgcgg tgcgcgtccg
    18241 gactacccgc ctagccggag ttcgacagtg tttgcgtggc tgtgcgagta gcggtgcggg
    18301 ttgacggccc acagcaagcg gctccgccgc ttatgacaac cagcgcgggt aacttggtgg
    18361 catgacgcaa actcggcagc cgcggcgacc ccggcagcgg acgggacggc gccccggggt
    18421 gttcgccggt gtggtggtgc tcgccctgct gctgttgttc ggtgtgccgt gggccacgct
    18481 ggtcctgccg tggcccacgc ccgtggtggt cgccggaaca gtcctcttcg gaatcgccgc
    18541 gccggccttc ccggtgctga tgttcctcgg gcacggccgc ggccgcgact gggccgcgcg
    18601 catcgcggac accgcgctcg gtgtggtctg ggtgttcttc gcgtggtcgg tgctcagcct
    18661 ggtggccagg gtcgcgctgc tcggcgtggc cgaaccgcgg cgctcgcgga tcatcgccgt
    18721 gctcgtgctg gtgatcggtg tcgcgctggt cggttacggg gtgcgcgaag ccatgcgcgt
    18781 gccgaggatc cgccgggtcg aggtgaccct gccccggctc ggctccggcc tcgacggcac
    18841 gaccgtggcc ctgctgaccg acacgcactt cggcccgctc gaccggacgc ggtggtcccg
    18901 gcgcaccgcc gccgcggtga acgcgctgaa gccggacatc gtcgcccacg ccggtgacct
    18961 cgccgacgga acggtcgagc agcggcgggc gcaggtcgcc ccgctgggca ccatcaccgc
    19021 cccgctggcg cgggtgtact cgaccggcaa ccacgagtac ttcggcgagg cgcaggcctg
    19081 gctggaccac atgagttcgc tcggctggga ctccctgcac aaccggcacg tggtggtcga
    19141 acgcggcggg caccggctga tcgtggccgg gatcgacgac gccaccgccc gcgcctccgg
    19201 cctcgacggg cacggcgccg aactggaccg ggcgctggac ggcgcgcccg aggacgtgcc
    19261 gatcctgctg ctggcccacc agccgaagca gatcgccgag accgcgaacc aggtcgacct
    19321 ccagctggcc gggcacaccc acggtggcca gatctggccg ttccactacc tcgtccgcac
    19381 cgaccagccc gtgctggagg gcctctccca gcacggcacc acccagctct acaccagccg
    19441 cggcgcgggt ttctggggac caccgctgcg tgtgttcgcc ccgagcgaga tcaccctgat
    19501 caccctgcgg gcgccctagg gtccacctgc accttggggc ccgggtactt cccggccagt
    19561 accgcgccga cctcgtcgag gccgacggtg gccgcgacca gcgggcgcgg gtcgacggtg
    19621 ccctcggcgt aggcggcgat ggtgtcggcc agtcccggtg acgccgagag aatgccgacc
    19681 gcggtgacgt ccttgagcac cagcgccctg gtgtcgatcc ggctgggccg cccggcgatt
    19741 cctatgtaga cgatccggcc gccaggctcg acgcggtcca gtgccagcgc gggcaggtgc
    19801 tcggcgttgg ccgcgtcgac gaccgcgtcg aacggcaggt ccgggacctc gccccaggtg
    19861 tgctcgaaac ccagtcccct ggcgaaatcg agcgacgaag cggtgcggcc cagcaggtgc
    19921 acctcggcac ctgccgcgcg caggaacaac gccaccagca gcccgatcgt gcccggtccc
    19981 atgaccagca cgcgatcacc gggcccggcg tcggccgccc gcgccgcccg gagcgcgttg
    20041 ccgcccggct ccaccagcgc cccgagcacc gcgtcgaccg aatccggcaa cgcgtgcagc
    20101 gaccagtcgg gcacggcgat ccgctcggcc agcgcgccgg gacggccgtc gcggatgccg
    20161 acctcctgcc ggtgctcgca cacgtgctgc aacccgcgaa ggcagcggcg gcaggtccgg
    20221 tcaccgagca tggtgtcgcc catgacccgg cggccgagcc agcccggatc gaccccgtcc
    20281 ccgatcgccg tcaccgtgcc cgcccattcg tgccccaggc gcagcgggta cgaggagtgc
    20341 ccctggtgca ggtaggccat ctcgccggtg aagaactcga catcggtgcc gcacaccccg
    20401 gcgcgctcga cgtcgaccac cacctcaccc ggaaccgccc gcggtgacgg cacttcccgc
    20461 acctcgtacg cctccggccc ggtgagcacg aaggcacgca tcaccggggc gcgagcacgc
    20521 gctgccgctg gcggccgagt ccgtcgatgc ccagttccat cacgtcaccc ggccgcagcc
    20581 acaccggcgg gcggaagccc atgcccacgc ccggcggggt gccggtgttg atcaggtcgc
    20641 ccggctccag caccatgaac tggctcaggt ggtgcacgat gaagtacggg tcgaagatca
    20701 tcgtccgggt gttgccggtc tgccgccgct gcccgttcac ctccagccac aggtccagcg
    20761 cgagcacgtc gtcgatctcg tccggggtga ccagccacgg cccggccggg ttgaaggtct
    20821 cggcggactt gcccttggcc cactgcccgc cgcgctccat ctggaacgcg cgctcgctga
    20881 cgtcgttgac caccaggtac ccggcgatcg ccgcgcgggc gtcggccacg gagtccaaat
    20941 aggacgtccg acggccgatg acgatgccca gttccacctc ccagtccggt ttggtcgaac
    21001 cacgcgggat gcgcacgtcg tcgtccgggc cgacgagggt gttgggcgac ttggtgaaca
    21061 ggatcggctc gtcgggcacg gcctgcccgg tttccgcggc gtggtcccgg tag
//
