LOCUS       NZ_CP045480            23628 bp    DNA     circular CON 15-AUG-2024
DEFINITION  Amycolatopsis sp. YIM 10 chromosome, complete genome.
ACCESSION   NZ_CP045480
VERSION     NZ_CP045480.1
KEYWORDS    RefSeq.
SOURCE      Amycolatopsis sp. YIM 10
  ORGANISM  Amycolatopsis sp. YIM 10
            Bacteria; Actinomycetota; Actinomycetes; Pseudonocardiales;
            Pseudonocardiaceae; Amycolatopsis.
REFERENCE   1  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Complete genome sequence of Amycolatopsis sp. YIM 10, isolated from
            a rare earth mine
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10312959)
  AUTHORS   Ruckert,C., Guerrero-Garzon,J.F., Zehl,M., Rezaei,S., Selivanova,G.,
            Urban,E., Busche,T., Kalinowski,J., Cao,Y.-R., Jiang,Y., Jiang,C.-L.
            and Zotchev,S.B.
  TITLE     Direct Submission
  JOURNAL   Submitted (11-OCT-2019) CeBiTec, Uni Bielefeld, Sequenz 1, Bielefeld
            33615, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Newbler v. 2.8
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 80.5x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009429145.1-RS_2024_08_15
            Annotation Date                   :: 08/15/2024 04:03:36
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,775
            CDSs (total)                      :: 9,711
            Genes (coding)                    :: 9,634
            CDSs (with protein)               :: 9,634
            Genes (RNA)                       :: 64
            rRNAs                             :: 4, 4, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 4, 4 (5S, 16S, 23S)
            tRNAs                             :: 49
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 77
            CDSs (without protein)            :: 77
            Pseudo Genes (ambiguous residues) :: 0 of 77
            Pseudo Genes (frameshifted)       :: 22 of 77
            Pseudo Genes (incomplete)         :: 65 of 77
            Pseudo Genes (internal stop)      :: 1 of 77
            Pseudo Genes (multiple problems)  :: 11 of 77
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 18:01:44
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3060920
            Orig. end                         :: 3084548
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045480.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Annotated using prokka v1.11 from http://www.vicbioinformatics.com.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..23628
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="5"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..23628
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23628
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:13628](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..13628)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            852..2009
                     /locus_tag="YIM_RS14965"
                     /old_locus_tag="YIM_15080"
     CDS             852..2009
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.4"
                     /locus_tag="YIM_RS14965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15080"
                     /product="sensor histidine kinase"
                     /protein_id="WP_153030942.1"
                     /transl_table=11
                     /translation="MGRVVIAVIAVLVDVVWLVPDRVVGVGWWAAPLFAGAIALLLLWR
                     RAVPGLVVATVLACLTGGGYALMLCASYRAGQQAGSRRDYLVVGLSAAAYLGVQLVGGP
                     QMVPKVLVLVVLPMVVGRYFAQHRRLVEALDEHNRRLRAERDLLAERERLTERLRIARD
                     MHDSLGHRLGLLSVQAAALEVGDSPDREAVRRLAGIARQATAELHELVGTLRSPVEVEP
                     REPRLAEVGGLVDEFRAAGVRVDLHSEGEARQVEPEVEQAAYRVVEEGLTNAAKHAPAA
                     EVRVSLRWEDDALLVSIRNGLPSAPGSGGGHGLTGLAERVALVGGLVHHERSETEFRLT
                     AMLPAPAPTEAEPRSLGRVRVAALVLAVVSMVVMVGPASAFGGAG"
     gene            2006..2638
                     /locus_tag="YIM_RS14970"
                     /old_locus_tag="YIM_15085"
     CDS             2006..2638
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015104412.1"
                     /locus_tag="YIM_RS14970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15085"
                     /product="response regulator transcription factor"
                     /protein_id="WP_153030943.1"
                     /transl_table=11
                     /translation="MIRVLIADDEPLITAGIRTVLESDAGIEVVAEAADGRTAVQLARA
                     HRADVAVLDLNMPELDGLSAVGELPGVPVVILTAFGVEPNVRRAIRQQVAGFVLKNCTP
                     DELIRAVRAAHAGEAYLSPEVARLVMDMVGTGDTERRESAAARLAALSPRESEVLGLLA
                     EGLSNAEIGARVHMSEATIKTYVSRILAKLGCANRVQAALLARDGLG"
     gene            complement(2612..2938)
                     /locus_tag="YIM_RS14975"
                     /old_locus_tag="YIM_15090"
     CDS             complement(2612..2938)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005439898.1"
                     /locus_tag="YIM_RS14975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15090"
                     /product="DUF3817 domain-containing protein"
                     /protein_id="WP_153030944.1"
                     /transl_table=11
                     /translation="MLTSPAGRFRLLALAEAVSWAGLLIGMFFKYVVVGNEIGVKIFGP
                     IHGVVFVAYVIVALLVRESLRWDGRTTVLALIASIPPFGTVLFERWATRTGRLDRSAEP
                     VASQ"
     misc_feature    3006..3021
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     gene            complement(3007..3963)
                     /locus_tag="YIM_RS49115"
                     /old_locus_tag="YIM_15095"
     CDS             complement(3007..3963)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS49115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_15095"
                     /product="hypothetical protein"
                     /protein_id="WP_228004732.1"
                     /transl_table=11
                     /translation="MLFTSLTGRRPFSVEGTAAQIWAHLREPPPRASTWNPSIPSTLDE
                     VIIRGMAKEPDQRFPTAGALAAAAREALAQPVAAPAPSRPRPARVLPRLASLLPVGLAL
                     LVIAAVVSTLLLVRGGNSLVSGVAIAGASSSSSPTNPPTPSIQSTPTSPSTRSSPTNPD
                     FPQLLPSVYRGNASCHEVEKADGALSTIICTETNETHPTFPGPAEADFHLFADRTSQDA
                     FFRKLVTDRHIPRQDQYGGCRPRTQDIHYALYYRDTSSPIPGEFTTCFTEEGTGQLWWV
                     DTRTLTIGALIAPGATSDDALAKLDTWWNTMILVTMK"
     gene            complement(3945..4553)
                     /locus_tag="YIM_RS49120"
                     /old_locus_tag="YIM_15100"
     CDS             complement(3945..4553)
                     /EC_number="2.7.11.1"
                     /GO_function="GO:0004674 - protein serine/threonine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.4"
                     /locus_tag="YIM_RS49120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15100"
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_228004733.1"
                     /sec_met_domain="Pkinase (E-value: 8.5e-35, bitscore:
                     119.5, seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPGETFGPYRIEEPLGRGGMGEVHRAYDTTHDRVVALKRLSESAV
                     GDPGFRARFRRESRIVARLREPHVIPIHAYGEIDGRLYLDMRLVEGPDLKELTDAGPLA
                     PARAVHIVEQVASALDAAHADGLVHRDVKPSNILVAAGDFVYLADFGIARSSSATATSI
                     TASGVMVGTLDYMAPERFGEARSTDAPMSTRSPACCSPA"
     misc_feature    4548..4563
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            complement(4594..5007)
                     /locus_tag="YIM_RS14985"
                     /old_locus_tag="YIM_15105"
     CDS             complement(4594..5007)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005167193.1"
                     /locus_tag="YIM_RS14985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15105"
                     /product="VOC family protein"
                     /protein_id="WP_194240156.1"
                     /transl_table=11
                     /translation="MKPSSFYPVICADAATVAPTRDFYVEHFGFEVVFDSGWYVSLRHD
                     GGHELGIVDHTHPSVPEGSRRPVAGLILNFEVDDVDAEHRRLVEEAGLSPVLPLRSEEF
                     GQRHFILTDPAGVLVDVITEIEPSAAFAADFTS"
     gene            5093..5695
                     /locus_tag="YIM_RS14990"
                     /old_locus_tag="YIM_15110"
     CDS             5093..5695
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010229472.1"
                     /locus_tag="YIM_RS14990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15110"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_153030946.1"
                     /transl_table=11
                     /translation="MPTKAQQREETTRNLVAVARSLFATKGYGQVSLAEIVAAAGVSKG
                     ALYHYFTGKDQLFRAVLEQVHAEVAERVGGAAPDADAWTQLVEGCTAFLTVTTEPEIQR
                     IMLVDAPAVLGWETWRELDATASMRHLAEALTQLIDEGVLIRQPVAPLAHLLSGAMNEA
                     AAWLAGSADPGRDLVDTVAALTRMLEAMKVQGRPVST"
     gene            5740..6825
                     /locus_tag="YIM_RS14995"
                     /old_locus_tag="YIM_15115"
     CDS             5740..6825
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1229: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011000070.1"
                     /locus_tag="YIM_RS14995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15115"
                     /product="IS630 family transposase"
                     /protein_id="WP_153030947.1"
                     /transl_table=11
                     /translation="MPNPKLPELVLSEDEVGMLRCWTRRRKTAQALALRARIVLRCAEG
                     GSNSEIAAELGITRATVAKWRSRFVTDRLDGLLDEARPGRPRTITDEQVEAVITATLES
                     APANATHWSTRSMAAESGLTQTAVTRIWNAFGLQPHRRESWKLSKDPLFVDKVKDVAGL
                     YLAPPERAVVLCVDEKSQIQALNRTAPVLPMLPGTPQRATHDYTRHGTSSLYAALDITT
                     GKVIGRLHARHRAIEFKKFLTAIDKEVPAELAVHLVMDNVSTHKTPVIKRWLASHPRFV
                     VHFTPTSSSWLNLVERWFSELTTKKLQRASHTSVRALNRDIRAWIETWNDDPRPYVWTK
                     TADQILDSIARYCTRINNSGH"
     gene            complement(6822..7658)
                     /locus_tag="YIM_RS15000"
                     /old_locus_tag="YIM_15120"
     CDS             complement(6822..7658)
                     /NRPS_PKS="Domain: TauD (6-250). E-value: 1.2e-59. Score:
                     194.2. Matches aSDomain: nrpspksdomains_YIM_RS15000_TauD.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TauD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1121: dioxygenase, TauD/TfdA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011874409.1"
                     /locus_tag="YIM_RS15000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15120"
                     /product="TauD/TfdA family dioxygenase"
                     /protein_id="WP_153030948.1"
                     /sec_met_domain="TauD (E-value: 1.9e-57, bitscore: 194.2,
                     seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASTFSVSPISGALGAEVRGVPLTSLSDADFAEVRELLLTHLVLF
                     FPDAAGLDPEAHKAFGRRFGELEVHPFLPKLEGHEELVVLDSEQGAKADVWHTDVTFSQ
                     SPPIASILQLVECPPAGGDTMWSNQYLAYEAISAPLRELLDGLTAVHVFEHPNGSFRSE
                     AEHPVVRTHPETGRRSLYVNRMFTRRIPQLAPGESDALLGYLFGMSESPQRVCRYRWTP
                     GAIALWDNRATQHYAVNDYTGRRVGQRVTVLGDKPEGEAPRWPHHEGAGLSAATSR"
     aSDomain        complement(6909..7640)
                     /aSDomain="TauD"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_YIM_RS15000_TauD.1"
                     /evalue="1.20E-59"
                     /label="YIM_RS15000_TauD.1"
                     /locus_tag="YIM_RS15000"
                     /protein_end="250"
                     /protein_start="6"
                     /score="194.2"
                     /tool="antismash"
                     /translation="VSPISGALGAEVRGVPLTSLSDADFAEVRELLLTHLVLFFPDAAG
                     LDPEAHKAFGRRFGELEVHPFLPKLEGHEELVVLDSEQGAKADVWHTDVTFSQSPPIAS
                     ILQLVECPPAGGDTMWSNQYLAYEAISAPLRELLDGLTAVHVFEHPNGSFRSEAEHPVV
                     RTHPETGRRSLYVNRMFTRRIPQLAPGESDALLGYLFGMSESPQRVCRYRWTPGAIALW
                     DNRATQHYAVNDYTGRRVGQRV"
     misc_feature    7649..7663
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     gene            7798..8784
                     /locus_tag="YIM_RS15005"
                     /old_locus_tag="YIM_15125"
     CDS             7798..8784
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803118.1"
                     /locus_tag="YIM_RS15005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15125"
                     /product="methyltransferase"
                     /protein_id="WP_153030949.1"
                     /transl_table=11
                     /translation="MDPAAQLAGLVDLATPFAVRAAVALRLPELVADGTTGLPALAEAA
                     GAHEDSLGRLLRHLVTIGLFTEENGTYGLTPLSRQLLGEDHRWQRGWLELDGPGAKMDL
                     AYSGMLHSVRTGESAYESVHGTPFWADYQRDERLRVFFGGIMAAHAWQTGPAVAAEYDW
                     APVRRVLDVGGGIGALLSEVLRQHPHLGGAVLDLPPVEPEAKQALADAGLAERAEFIGG
                     SFFDPLPGGFDVLMVSRVLTDWGDEDATRILRRCAEAASTVLIVEVLAGEEHAKNNSSF
                     DLQSLTLLGGRERSIEDFRVLAAAAGLVVRTERTAPGGLVLIECGVG"
     gene            complement(8790..10004)
                     /locus_tag="YIM_RS15010"
                     /old_locus_tag="YIM_15130"
     CDS             complement(8790..10004)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1050: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010312129.1"
                     /locus_tag="YIM_RS15010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15130"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_153030950.1"
                     /transl_table=11
                     /translation="MRTEAIVCGAGVAGLATACALGNLGLRVALVDKQDAPKPVAKGEV
                     FQPGSLRILRSWGVAQRLESAGALRLARLVARDSAGTPQMALDYGTLPGKDRWLLAHDY
                     PAILTALTESLPSTVEFRRGVLVKGLLRNQDGQVTGVRLADGTIEAPLVVAADGMSSRL
                     RKEAGIEITRAEYPHRLVALELHDAPEVEADFSAYVTERGLRLRYPLPGGRIRLYAQVR
                     PDELRGGDLVSWGRALARETPALTPLEDAILAALPERQVLPVARFLAPKLWIPGLALAG
                     EAGHAVHPMAAQGMNSAIADADCLATVLAESGDLASYHRRRQADLALIGRTSHAAARMI
                     TDLSWAGRTLGRRALRHTGANQRLRYTVMHNMSGLGSHPLTPLDRLHQIGLLPDPRARR
                     LPAWA"
     gene            complement(10001..11656)
                     /locus_tag="YIM_RS15015"
                     /old_locus_tag="YIM_15135"
     CDS             complement(10001..11656)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943462.1"
                     /locus_tag="YIM_RS15015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15135"
                     /product="prenyltransferase/squalene oxidase
                     repeat-containing protein"
                     /protein_id="WP_153030951.1"
                     /sec_met_domain="T2TS (E-value: 5.3e-32, bitscore: 110.1,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSLRADELSEAIATGAEALFSAQRPDGVFDYGEHALTSTLGTVG
                     AVSALHFADPTGSADLIARGAAWLERTQADDGGWSMVPGEASEAGPTAVATATLHLLGN
                     SASAVHKGQEWLRAYGGLEAIPHAEVVAWCRQYYGFAGWLDPREMRRFPLELALLPGLY
                     RKLFDLRAPMVSALGLAQTRHKPIGRVHRALSKLAEPKALDVIRQVYEHEGGTGGWCED
                     AWVTGLIVAGLARADLGHDMVAGAVRWFRENANEDGSWNSGPLDLTWSMYAAAGLLEAG
                     YRDDARLGLTKDLFLRLQQDQPFVAFGCPPGFWGWSGTRGWPATLETGEIVSALCHLPG
                     EDQAESVQRGVTWLTLQQDTRGSWGLCVRNTKVANSGPCPHMTAQALDGLLDSGVPAAD
                     RRVHRGLRWLASAQRPDGSFESVWYRMHTAGTSAVLQTFAKAGQSGEPAAVRARSWLER
                     TRHEDGSWGTGDPADPGTVEETGWAVSALLAAGAPADSVLPGVRWLLAARDPGGGWPAA
                     RVNEYVRHVSRYANPALANGLALRALARYRKAVR"
     gene            complement(11653..12630)
                     /locus_tag="YIM_RS15020"
                     /old_locus_tag="YIM_15140"
     CDS             complement(11653..12630)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ubiA"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010312127.1"
                     /locus_tag="YIM_RS15020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15140"
                     /product="UbiA family prenyltransferase"
                     /protein_id="WP_228004734.1"
                     /sec_met_domain="ubiA (E-value: 1.9e-16, bitscore: 59.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGPRWRSAAVAHVQTWRPYTLCYPAMLGLAGAAAAGEPVAPTAA
                     LVPALGWLSGHYLGDYFDRGLDAIGKPHRPIPSGRLSAEAALLGGIACALASAVLAAGS
                     NWRILPVFVLAMLGIVGYSKVFKKRGAAGNVVRGALSALAVVIGAMLVVPLPPWSVLPV
                     ALGFLAHDTASNLVGTVRDVDGDRAGGYRSVPVRHGVRHAVRLALGLYVTGVLFIASAA
                     WFIPDPSAHLTLVLLAAVAGAVAFTPLFRDAVDRSVALRAHEVLVGERLVLAAAVVAGS
                     AGPAFALAVLVPVLVLSLATQAVMRARHEIPPAPALLRRKDTVA"
     gene            complement(12627..13628)
                     /locus_tag="YIM_RS15025"
                     /old_locus_tag="YIM_15145"
     CDS             complement(12627..13628)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943464.1"
                     /locus_tag="YIM_RS15025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15145"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_153030952.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.1e-54, bitscore:
                     181.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAIGEVTSSPAVEDVRRALNERWSGTDHRVAEISGYALLPAGKL
                     LRPLLLVTAAEAVGGTREQVLPAALAVEYLHVASLIHDDIIDGDDLRRGRPAVHARFGT
                     PDAIVTGDALLLGLFSAVAECASLGVPEPAVLAAVQVLAGAGEDLCRGQVQEALLDKEV
                     LASGVEHCLTAYLEMAALKTGALFRGACRAGALLGGGSPAEVAAITGFAEHAGLAFQMH
                     DDLLPFLGDPSVTGKPGTSDAANLRLTFPVLLAIRETGPAPLERILGGALPPERTLAEL
                     RELVTATGALDLARTRAEEEVALARAELGTLPSGEATALLGSIAEAAVRRDR"
     gene            complement(13625..14584)
                     /locus_tag="YIM_RS15030"
                     /old_locus_tag="YIM_15150"
     CDS             complement(13625..14584)
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Aminotran_1_2 (4-305). E-value: 2.2e-43.
                     Score: 140.7. Matches aSDomain:
                     nrpspksdomains_YIM_RS15030_Aminotran_1_2.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019: aminotransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015803122.1"
                     /locus_tag="YIM_RS15030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15150"
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="WP_228004735.1"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.2e-41, bitscore:
                     140.8, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNENHSPPLPGVRRAIEDGADRVHLTQDALAGGLTAELARRLGVA
                     AERVVAGAGSGALIQQFLNAHAGSGARVVHSWPSFELYPLLIGNAGGTPVAVPGEPQDL
                     RALAAAVTSETRVVLLCNPNNPTGEVLGHAEVAEFVDLLPPDVLVLIDEAYREFASPGE
                     LADGLALAATDDRVAVVRTFSKSHGLLGLRVGYLVASEPVAAALRPTLPFFRVGTLAQA
                     AALAALDAEARMREQCAEVATERDRVRAGLLDLGWDVPPSGGNFLWLRLGPQNQSFVDH
                     LAAAGVAVREIAGAGVRVSTGTPEANDLVLALAKEFAA"
     aSDomain        complement(13670..14572)
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_YIM_RS15030_Aminotran_1_2.1"
                     /evalue="2.20E-43"
                     /label="YIM_RS15030_Aminotran_1_2.1"
                     /locus_tag="YIM_RS15030"
                     /protein_end="305"
                     /protein_start="4"
                     /score="140.7"
                     /tool="antismash"
                     /translation="HSPPLPGVRRAIEDGADRVHLTQDALAGGLTAELARRLGVAAERV
                     VAGAGSGALIQQFLNAHAGSGARVVHSWPSFELYPLLIGNAGGTPVAVPGEPQDLRALA
                     AAVTSETRVVLLCNPNNPTGEVLGHAEVAEFVDLLPPDVLVLIDEAYREFASPGELADG
                     LALAATDDRVAVVRTFSKSHGLLGLRVGYLVASEPVAAALRPTLPFFRVGTLAQAAALA
                     ALDAEARMREQCAEVATERDRVRAGLLDLGWDVPPSGGNFLWLRLGPQNQSFVDHLAAA
                     GVAVREIAGAGVRVSTGTPE"
     misc_feature    complement(14566..14581)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.05"
                     /tool="antismash"
     misc_feature    complement(14732..14745)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.19"
                     /tool="antismash"
     misc_feature    14735..14751
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.92"
                     /tool="antismash"
     misc_feature    14954..14971
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 17.66"
                     /tool="antismash"
     misc_feature    complement(14967..14978)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.24"
                     /tool="antismash"
     gene            15076..16251
                     /locus_tag="YIM_RS15035"
                     /old_locus_tag="YIM_15155"
     CDS             15076..16251
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MGT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1062: glycosyltransferase, MGT family"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009943467.1"
                     /locus_tag="YIM_RS15035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15155"
                     /product="glycosyltransferase"
                     /protein_id="WP_153030954.1"
                     /sec_met_domain="MGT (E-value: 1.9e-68, bitscore: 230.7,
                     seeds: 193, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVLTCLPFYSHLVPVVLPVARALRRAGHEVAVATAPGMASEVT
                     AAGIEHLALPNVLTLAQLLDRPDVATSPGMPGDPAGSARAATARAESGPLAAAFAGPLA
                     GVFARDLIRACEFWTPDLIVRECNEFGGHLAAERLGVRQAVLDIAPGSTATLPSVRDAL
                     NGQRVELGLAEVDDPWYPNRTFVAGFVPPGWYPADPPRCYRLGEPDGVLDGSLDLPADR
                     PLVVAGLGSVAATVVPESPELLELLITALGRLPVTAVVGLGSDARRWPGSRPDNVRLLE
                     FAPQRLLLESAELFVSHGGFGGVAEAVRTGTPMVVLPLFSDQPYNAERVAALGLGVRLD
                     PAGLDPEVLADACAKVLDDQAYRRNSAAMSRRALGCPGLETLAEDLFAHHR"
     misc_feature    complement(16274..16290)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.2"
                     /tool="antismash"
     gene            16373..16705
                     /locus_tag="YIM_RS15040"
                     /old_locus_tag="YIM_15160"
     CDS             16373..16705
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="YIM_RS15040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="YIM_15160"
                     /product="hypothetical protein"
                     /protein_id="WP_153030955.1"
                     /transl_table=11
                     /translation="MASRNVTRLFGMLDRPLGEPEAVALAERMYGADLIAVAVRERRFG
                     VASRTDDNPYPALELAGQAFVEVLAEAGFTVKSWESVEWLSGAEAQLREDTEDFAEWLP
                     APLAAP"
     gene            16765..17748
                     /locus_tag="YIM_RS15045"
                     /old_locus_tag="YIM_15165"
     CDS             16765..17748
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020666059.1"
                     /locus_tag="YIM_RS15045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15165"
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="WP_153030956.1"
                     /transl_table=11
                     /translation="MPGESAAQLIEAARAGDPDAFGGLVDPFRDELQAHCYRMLGSVHD
                     AEDALQETLVRAWRALPKFDPAAGTVRSWLYKIATNRCLTAIERRGRRELPADLGPGAP
                     ETEVSWLEPYPDDRLGPEARYVARESVELAFVAALQHLGARQRAVLLLREVLEFSANEV
                     ADLLETSVAAVNSALQRARRTLDPQRTSQRAELAAVGADGVRELADRYADAWQRGDLQA
                     IVDMLTEDARYSMPPLFEWYSGHDGIREFLASGPLRRRWRFVPVRANGQLAFGTYRWDG
                     DRDAFVPSGLDVLAVRGDRIAEVVSFLDADFSRFGLPESLPEPAGP"
     gene            complement(17745..18458)
                     /locus_tag="YIM_RS15050"
                     /old_locus_tag="YIM_15170"
     CDS             complement(17745..18458)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637829.1"
                     /locus_tag="YIM_RS15050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15170"
                     /product="2OG-Fe(II) oxygenase"
                     /protein_id="WP_153030957.1"
                     /transl_table=11
                     /translation="MDKYAKRVAAADWGAVGTELGDLGCALLPRLLTQAECRRIAALWT
                     ETDRFRATINLRRHRFGDHGDYRYFAEPFPEPVAALREALYPRLLPIARDWYAKLGREA
                     EWPDTLAEWLRICHDAGQTRPTPILLRYETGGWNALHRDLYGEKVFPLQVVINLDEPGT
                     DHTGGEFLLVEQRPRAQSRGTSTLIPQGHGLVFTTRDRPVASARGWSAAPVRHGVSPVR
                     SGRRHTLGLVFHDAT"
     gene            18531..19319
                     /locus_tag="YIM_RS15055"
                     /old_locus_tag="YIM_15175"
     CDS             18531..19319
                     /NRPS_PKS="Domain: PKS_KR (11-174). E-value: 2.2e-12.
                     Score: 39.2. Matches aSDomain:
                     nrpspksdomains_YIM_RS15055_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020630302.1"
                     /locus_tag="YIM_RS15055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15175"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_153030958.1"
                     /sec_met_domain="adh_short (E-value: 6.6e-31, bitscore:
                     106.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.1e-37, bitscore:
                     129.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MILDRFLLTGRVAVVTGAGRGIGAATAVALAEAGADVVLAARTEE
                     QLREVAGQVEAAGRKAEVVAADLSDPAAAAALADAATGAFGRLDIVVNNVGGTLPRPLL
                     ETSPRFLEEAFRFNVATAHALTRAAAPAMLAAGGGAVVNISSALGRVAGRGYLAYGTAK
                     AALAHYTRLAAADLAPKIRVNAIAVGTVLTSALEIVAANPELKERMEQDTPLRRLGEPE
                     DIAAAVLYLTSPAGAYLAGKVLEVDGGLQAPNLDLGLPDL"
     aSDomain        18564..19052
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_YIM_RS15055_PKS_KR.1"
                     /evalue="2.20E-12"
                     /label="YIM_RS15055_PKS_KR.1"
                     /locus_tag="YIM_RS15055"
                     /protein_end="174"
                     /protein_start="11"
                     /score="39.2"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAVVTGAGRGIGAATAVALAEAGADVVLAARTEEQLREVAGQVEA
                     AGRKAEVVAADLSDPAAAAALADAATGAFGRLDIVVNNVGGTLPRPLLETSPRFLEEAF
                     RFNVATAHALTRAAAPAMLAAGGGAVVNISSALGRVAGRGYLAYGTAKAALAHYTRLAA
                     "
     CDS_motif       18570..18656
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_YIM_RS15055_0001"
                     /evalue="3.60E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="YIM_RS15055"
                     /protein_end="42"
                     /protein_start="13"
                     /score="13.2"
                     /tool="antismash"
                     /translation="VVTGAGRGIGAATAVALAEAGADVVLAAR"
     gene            complement(19323..19748)
                     /locus_tag="YIM_RS15060"
                     /old_locus_tag="YIM_15180"
     CDS             complement(19323..19748)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020637590.1"
                     /locus_tag="YIM_RS15060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15180"
                     /product="SgcJ/EcaC family oxidoreductase"
                     /protein_id="WP_153030959.1"
                     /transl_table=11
                     /translation="MTIEEIISGMQRAWNAGDGAGWGAHFAEDADFVDAVGRIQRGREV
                     IGSEHQKIFDTIYQGSVLEIRLVDSRPLGDGLLLVHTDSTLQVPAGPRKGTVDGVQTKL
                     IRDGLIHAFHNTVRGDLATFTKHDPALASRSPLDWKS"
     misc_feature    complement(19768..19782)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.46"
                     /tool="antismash"
     misc_feature    19792..19806
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.12"
                     /tool="antismash"
     gene            19810..20415
                     /locus_tag="YIM_RS15065"
                     /old_locus_tag="YIM_15185"
     CDS             19810..20415
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020674082.1"
                     /locus_tag="YIM_RS15065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15185"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_153030960.1"
                     /transl_table=11
                     /translation="MAADLPGIVRLRDRREALTLRTILTAARGLFAERGYARTPIRLIA
                     QEAGVAPQTIYAHFGSKAGVLGGLVDLLDDEAGLPDLVASAEDLTDPADLLGLLAKASR
                     QVRERCGDIVAILSSGAAVDPDIAATEAEGARRNRLGVEMVIERIRSAGHRIEPRAVDI
                     AVALMSAGVHDSLVGAAGWSPDDYEDWLRKTLVSAVLN"
     misc_feature    20023..20025
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20396..20785)
                     /locus_tag="YIM_RS15070"
                     /old_locus_tag="YIM_15190"
     CDS             complement(20396..20785)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020633572.1"
                     /locus_tag="YIM_RS15070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15190"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_153030961.1"
                     /transl_table=11
                     /translation="MNKHRLVTAFQRHVGNPILRRLPFQVLLETTGRKSGLPRQTPVGG
                     RRVGDEFWFVSEFGEKSQYIRNIQADPSVRVRLRGRWYSGIAHLEPDDDARARLKSLPR
                     LNSAAVRAMGTDLLSVRVDLSSAPR"
     gene            complement(20782..22233)
                     /locus_tag="YIM_RS15075"
                     /old_locus_tag="YIM_15195"
     CDS             complement(20782..22233)
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1112: sigma-54
                     dependent trancsriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017982940.1"
                     /locus_tag="YIM_RS15075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15195"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_153030962.1"
                     /transl_table=11
                     /translation="MTRALEVDVEQRQLSPDRPRLLASWQRSERYGVSLDEVTPVFTGS
                     VDTGSLLYECGYEVLSGLQATLANEPVSLMITDSAGLVLARLCNDNSINRSLDRVHLAP
                     GFYFAERNAGTNGLGLALADRAPTLVRAEEHYCTGLRGYTCAAVPVLDPLTGDLAGSVN
                     LTTWSNSSSELLLALAQAAAGNTTALMLARSAGRRMRPTPRGEVFHVYADRFPQADGGR
                     LWSDAVAEAHTALAAGRVVAVVGEPGAGKTALASMAHRRARPRERVLSARPPAPEDVHA
                     WLTLWTPELEKDDTCVIVSGVDGLPAWAAGELARQFASVRHDDARPQPFVLTAEDFGAL
                     PGPLGALVDTVVEAPPLRHRPDDIMPLARHFAERERGRPISFTSAASRALTEYHWPENV
                     KQLKRVARTAAARADVVDQRHLPAKLFSSGAHRLSRLQALERDEIVRCLTEPGATVVRA
                     AAELGMSRATIYRKMAQYEIKVPGR"
     misc_feature    complement(22289..22303)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.98"
                     /tool="antismash"
     gene            22388..23401
                     /locus_tag="YIM_RS15080"
                     /old_locus_tag="YIM_15200"
     CDS             22388..23401
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009945967.1"
                     /locus_tag="YIM_RS15080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="YIM_15200"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_153030963.1"
                     /transl_table=11
                     /translation="MYSKDGENYFIVDAHIALWDARPENQLNVHGKQFIDCFYDYHRNL
                     SPESELWPYEEYLYYGGERLMKDLFEDGYVDHAIFQPARLGAFYKNGFGQTEEAFALAS
                     KHPDKLTYNHCYDPRFEQAGLEQLRRDADRFGLKGVKLYTAEWKGDSRGYKLDDPWSYR
                     YLEACRELGIRNIHIHKGPTIRPLDRDAFDVADVDHAATDFTDLNFVVEHCGLPRLEDF
                     CWIATQEPNVHAGLAVAMPFIHTRPRYFAQIIGELLYWLGEDRIQFSSDYALWTPRWLV
                     ERFVDFQIPADMTEYAPITVAQKKKVLGLNAAAMYGIEVPAGLGLKTPGLETPVGV"
     misc_feature    complement(23557..23577)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.06"
                     /tool="antismash"
ORIGIN
        1 attccgtgga ccgacagcgc ttcgtcggat tccgcgacaa cctcggcacc ggcgccgcga
       61 agaacgtcgg aaagttcgac ggctcgtggt gagcggacaa aaacgccgcg ctggaagcgt
      121 tcctcgagtt cacgaacgga ggtgtcggcg atcagccggc cgcgcccgat cacgatgaga
      181 cggtccgcgg taagggccat ctcgctcatc aagtggctcg acaccagtac ggtccggcct
      241 tctgcggcca gcgagcgcag cagttcgcgg atccagcgca cgccgtcggg atccaggccg
      301 ttcaccggct cgtcgagcag gagaacggcg gggtcaccga gcaatgcggc ggcgaggccc
      361 agccgttgct tcatgcccag cgagaacttg cccgcccgtt tccttgccgc gtcggtcaaa
      421 ccgacctgct ccagcacttc ccgaactcgt gtgcggccga tgccgtttgt cagtgccagc
      481 gacagcaggt ggtcgtaggc gctgcgccca ccgtgcaccg cgttcgcgtc gagcagggcg
      541 cccacttcga acatcggccg ccgcagggtg gcgtaccgcc ggccgccgac aagggcctcg
      601 ccggcgtcgg gtgcgtccag gcccaggacg atccgcatgg tcgtggactt tccggcgccg
      661 ttcggtccca ggaagccggt gacaccgccg ggcttcacgg tgaaggacag gtcgtcgacc
      721 gcggtcgccc ggccgtagcg tttgctcagt tcgcgcactt cgatcacgct cgcaggttag
      781 gaacggcgaa ccggcgggcg ctgtcctcga aggtcgctcc tggtgttcac caaagtcgct
      841 agcctcaccg catgggccga gtggtgatag ccgtgatcgc cgtgctggtg gacgtggtct
      901 ggctggtgcc ggaccgggtg gtcggtgtgg gctggtgggc ggcgccgttg ttcgctgggg
      961 cgatcgcgct gcttctgttg tggcgccggg cggtgccggg gctcgtggtg gcgactgtgc
     1021 tcgcgtgcct caccggtggc ggatacgcgc tcatgttgtg cgcgagttat cgcgccggtc
     1081 aacaggctgg atcgcgacgc gactacctgg tggtcggttt gtcggccgcg gcttacctcg
     1141 gtgtgcagct cgtgggcgga ccgcagatgg tgccgaaggt gctggtgctg gtggtgttgc
     1201 cgatggtcgt cggccggtac ttcgcgcagc atcggcggct cgtcgaggcg ctcgacgagc
     1261 acaaccggcg gttgcgcgcc gagcgcgacc tgctggccga gcgggaacgg ctgaccgagc
     1321 gactccggat cgccagggac atgcacgact cactcgggca tcgtctcggg ttgctgtcgg
     1381 tgcaggccgc cgcgctggag gtcggcgatt caccggaccg cgaggcggtg cggaggctgg
     1441 ccgggatcgc ccgccaggcg accgccgagc tgcacgagtt ggtcggcacg cttcgcagtc
     1501 cggtcgaggt cgagccccgt gaaccgaggc tggcggaggt cggcggtttg gtcgacgagt
     1561 tccgtgccgc cggagtgcgg gtcgatctgc acagcgaggg cgaggccagg caggtggagc
     1621 cggaggtcga gcaggcggcg taccgggtgg tcgaggaggg actgacgaac gcggccaagc
     1681 acgcgcccgc cgccgaggtc cgggtgtctt tgcgctggga ggacgacgcg ctgctggtga
     1741 gtatccgcaa cggattgccc agcgcaccgg gaagtggcgg agggcatggg ctgaccgggc
     1801 tggctgagcg cgtcgctctg gtcggcgggt tggtgcacca cgaacggtcc gagacggagt
     1861 tccggttgac ggcgatgctg cctgctccgg cgccgacgga ggccgagccg cggtcgctgg
     1921 gccgggtgcg ggtggccgcg ctggtactcg ccgtggtgtc gatggtggtc atggtcgggc
     1981 cggcgagcgc gttcggcggc gcgggatgat ccgcgtcctg atcgccgacg acgagccgtt
     2041 gatcaccgcc ggcattcgga ccgtgctcga atcggacgcc gggatcgagg tggtcgccga
     2101 agccgccgac gggcggaccg cggtccagct cgcgcgtgcg caccgggccg acgtcgccgt
     2161 gctcgacttg aacatgcccg agctggacgg gttgtcagcc gtgggggagt tgcccggcgt
     2221 gccggtggtc atcctgaccg ccttcggcgt cgaaccgaac gtccgccggg cgatccggca
     2281 gcaggtcgcc gggttcgtgt tgaaaaactg cacgccggac gagttgatcc gcgccgtccg
     2341 cgcggcgcac gccggggagg cctacctgtc gcccgaggtg gcgcggctgg tgatggacat
     2401 ggtcggcacc ggcgacaccg aacgcaggga gagcgcggcc gcgcgcctgg ccgcgctgtc
     2461 cccgcgtgag tcggaggtgc tcgggttgct cgccgaaggc ctgtcgaacg ccgagatcgg
     2521 cgcccgggtg cacatgagcg aggccaccat caagacctac gtcagccgca tcctggccaa
     2581 actgggctgc gcgaaccggg tgcaggccgc gctactggct cgcgacgggc tcggctgagc
     2641 ggtccaggcg cccggtgcgg gtggcccagc gctcgaacaa cacggtgccg aacggcggga
     2701 tgctggcgat cagggcgagc acggtggtgc ggccgtccca gcgcagcgac tcgcgcacca
     2761 ggagcgcgac gatcacgtag gcgacgaaca ccacgccgtg gatcgggccg aagatcttca
     2821 cgccgatctc gttgccgacc acgacgtact tgaagaacat gccgatcagc aggccggccc
     2881 aggacaccgc ctcggccagg gccagcaggc ggaaacgtcc ggcggggctg gtgagcacga
     2941 agctctccct tcggtggggg atttgtcccc attgtggagc tggtgccaag gccgccaccg
     3001 ggcgggtcac ttcatcgtca ccaagatcat cgtgttccac cacgtgtcca acttcgccag
     3061 tgcgtcgtcg ctggtcgcgc cgggggcgat cagtgcgccg atggtgagcg tgcgggtgtc
     3121 cacccaccac aactggccgg tgccctcctc ggtgaagcag gtggtgaatt cgccggggat
     3181 cgggctgctg gtgtcgcggt agtacagcgc gtagtggatg tcctgcgtgc gcggacggca
     3241 gccgccgtac tggtcctggc gagggatgtg ccggtcggtc accagcttcc ggaagaaggc
     3301 gtcctggctc gtgcgatcgg cgaacaagtg gaagtcggct tccgcggggc ccgggaaagt
     3361 cgggtgtgtt tcgttcgtct cggtgcagat gatggtcgac agggcgccgt cggctttttc
     3421 gacctcgtgg cacgaggcat tgccgcggta gacgctgggc agcagttgcg ggaaatcggg
     3481 gttggtcggg gacgagcgtg tgctggggga ggtgggcgtc gactgaattg acggagtggg
     3541 cgggttcgtc ggagaggacg acgaggacgc gccggcgatc gcgacgccgg acaccagtga
     3601 gttgccgccg cggacgagca ggagagtgga gacgaccgcg gcgatcacca gcagcgcgag
     3661 tccgaccggc aacagcgagg caagacgagg cagcacccga gcgggacgcg gacgggatgg
     3721 cgctggtgcc gcgacgggtt gagcgagtgc ttcgcgagcc gcggcggcga gggcgcccgc
     3781 ggtggggaag cgctggtccg gctccttggc catgccgcgg atgatcactt cgtcgagcgt
     3841 cgacggaatc gacgggttcc aggtcgacgc gcgcggcggc ggttcccgca ggtgcgccca
     3901 gatctgcgcg gccgtgcctt cgacgctgaa cgggcgccgc ccggtcaggc tggtgaacag
     3961 cacgcaggcg agcgcgtaga catcggtgcg tccgtcgacc ttgcctcgcc gaaccgctcg
     4021 ggcgccatgt agtcgagcgt gccgaccatg acgcccgacg cggtgatcga cgtcgccgtg
     4081 gccgacgagc tgcgcgcgat cccgaagtcg gccaggtaga cgaagtcccc ggccgcgacc
     4141 aggatgttcg acggtttgac gtcacggtgc acgagcccgt cggcgtgcgc ggcgtccagt
     4201 gcgctcgcga cctgctcgac gatgtgcacg gcccgcgccg gcgcgagcgg gcccgcatcg
     4261 gtgagttcct tcaggtccgg tccttcgacc aggcgcatgt ccaggtacag gcgcccgtcg
     4321 atttccccgt aggcgtggat cgggatcacg tggggttcgc gcagccgcgc gacgatccgc
     4381 gactcgcgcc ggaaccgggc gcggaaaccg gggtcgccga cggccgactc ggacagccgc
     4441 ttcagcgcga cgacccggtc gtgggtggtg tcgtaggcgc gatgcacctc gcccatgccg
     4501 ccacgcccga gcggttcctc gatgcggtac ggcccgaagg tctcacctgg catgcctgat
     4561 cgacgcctgg tgcgcccgcc gggttccctc ggttcagctg gtgaagtcgg cggcgaaggc
     4621 ggccgacggc tcgatctcgg tgatcacgtc gacgagcacg cctgccggat cggtcaggat
     4681 gaagtgccgc tggccgaact cctcgctccg caacggcagg accggggaca acccggcctc
     4741 ctcgaccagt cgccggtgct cggcgtcgac gtcgtcgacc tcgaagttca ggatcagccc
     4801 ggcgaccggt ctgcggctgc cctccggcac cgacgggtgc gtgtggtcga cgatgccgag
     4861 ttcgtggccg ccgtcgtggc gcaggctgac gtaccagccc gagtcgaaga cgacctcgaa
     4921 gccgaagtgc tcgacgtaga agtcacgggt cggggccacg gtcgcggcgt cggcgcagat
     4981 gacggggtag aagctggacg gtttcacggc gactccttgg atacgtaccg gcggtcggta
     5041 tgtgttcgaa ccataaatac cgaccgtcgg tacgtcaagt agggtggcaa ccatgccgac
     5101 gaaggcgcag cagcgcgagg aaaccacccg caacctggtc gcggtggccc ggtcgctttt
     5161 tgcgacgaag ggctacggcc aggtgagcct cgccgagatc gtcgccgccg ccggggtgtc
     5221 caagggcgcg ctctaccact acttcaccgg caaggaccag ctcttccgcg cggtgctgga
     5281 gcaggtgcac gccgaggtcg ccgagcgcgt gggcggtgcc gcgccggacg cggacgcctg
     5341 gacgcagctg gtcgagggct gcaccgcgtt cctcaccgtg accaccgagc cggagatcca
     5401 gcggatcatg ctggtcgacg cgccggcggt gctcggctgg gagacctggc gcgaactcga
     5461 cgcgaccgcg tcgatgcgtc acctcgccga ggcgctgacc cagctgatcg acgagggcgt
     5521 gctgatccgc cagccggtgg ccccgctcgc gcacctgctc tccggcgcga tgaacgaggc
     5581 cgccgcctgg ctggccggct cggccgaccc gggccgcgat ctcgtggaca ccgtggccgc
     5641 gctgacccgg atgctcgaag cgatgaaggt ccagggccgt ccggtaagta cctagtgtcc
     5701 tgagtcgtta gttcgtgtgc aggcgtaggg ttcggtggca tgccgaaccc gaagctgccc
     5761 gagttggtgt tgtccgagga cgaggtgggc atgttgcggt gctggacgcg gcgccggaag
     5821 acggcgcagg cgctggcctt gcgggcccgg attgtgttgc ggtgcgccga aggtggctcg
     5881 aacagcgaga tcgccgcgga gttggggatt acgcgggcga cggtggcgaa gtggcggtcg
     5941 cggttcgtga ccgaccggct ggatgggttg ctggacgagg cgcgtcctgg gcgtccgcgc
     6001 acgatcaccg atgagcaggt cgaggcagtg atcaccgcga cactggagtc ggcgcccgcg
     6061 aatgccacgc actggtcgac ccggtcgatg gccgcggagt cggggttgac ccagaccgcg
     6121 gtgacgcgga tctggaacgc gttcggcctg cagccgcatc gccgtgaatc atggaagttg
     6181 tccaaggacc cgttgttcgt ggacaaggtc aaagacgtcg ccgggctcta tctcgctccg
     6241 ccggagcggg cggtggtgct gtgcgtggac gagaagtccc agatccaggc gctcaaccgc
     6301 accgctccgg ttctgccgat gctgcccggc acgccgcagc gcgccacgca cgactacacc
     6361 cggcacggca cctccagcct gtatgcggca ctggacatca ccaccggcaa ggtcatcggc
     6421 cggctgcacg cacgccaccg cgcgatcgag ttcaagaaat tcctgaccgc catcgacaaa
     6481 gaagtgcccg ccgaactggc ggtgcacttg gtgatggaca acgtctcgac ccacaagacc
     6541 ccggtgatca aacgctggct ggccagtcat ccgcgcttcg tcgtgcactt caccccgacg
     6601 tcgagttcct ggctcaacct cgtcgaacgc tggttctccg aactcacgac caagaaactc
     6661 caacgcgcga gccacaccag cgtccgcgca ctcaaccgcg acatccgcgc ctggatcgaa
     6721 acctggaacg acgacccacg accctacgtc tggaccaaaa ccgccgacca gatcctcgac
     6781 tccatcgcac gctactgcac acgaattaac aactcaggac actagcggct cgtcgcggcg
     6841 ctcaggccgg cgccttcgtg gtgcggccag cgcggcgcct cgccttccgg cttgtcgccg
     6901 agcacggtca cccgctgacc gacgcgacgg ccggtgtagt cgttgaccgc gtagtgctgg
     6961 gtggcgcggt tgtcccacag cgcgatcgcg cccggcgtcc agcggtagcg gcagacccgc
     7021 tgcgggcttt ccgacatgcc gaacaggtaa ccgagcagcg cgtcgctttc gccgggcgcg
     7081 agttgcggga tgcgccgggt gaacatgcgg ttcacgtaca gcgagcggcg cccggtttcc
     7141 gggtgcgtgc gcaccaccgg gtgctcggcc tcgctgcgga acgaaccgtt ggggtgctcg
     7201 aagacgtgca ccgcggtgag tccgtcgagc agttcacgca gcggcgcgga aatggcttcg
     7261 taggcgaggt actgattgct ccacatcgtg tcgcccccgg cgggcgggca ttcgaccagc
     7321 tgcaggatcg aggcgatcgg cggcgactgg ctgaaagtga cgtccgtgtg ccacacgtcc
     7381 gctttcgcgc cctgctcgga atcgaggacg acgagttcct cgtggccttc gagcttgggc
     7441 aggaacgggt gcacctccag ctcaccgaag cggcggccga aagccttgtg cgcctcggga
     7501 tcgagaccgg cggcgtccgg gaagaacaac accaggtggg tcagcaggag ttcgcggacc
     7561 tcggcgaagt cggcgtcgga caacgaggtc agcggtaccc cgcggacctc ggcgccgagt
     7621 gcgccggaaa tgggtgaaac ggagaacgtg gaagccattt cgaaaacacc ttttcgggca
     7681 ggttggaaac acgattggcg aaaaagaaaa tgcttgaccg gaattgccgg tggatgtgat
     7741 tctcggaggt gaaccgagcg ccgcgaccgg tggcgccctg ccgactggag gacctggatg
     7801 gatcccgctg cccaactggc cggcctggtc gatctcgcca ccccgttcgc cgtgcgcgcg
     7861 gcggtcgcgt tgcgcctgcc ggaactggtc gcggacggca ccaccggcct gcccgcactc
     7921 gccgaagcgg ccggtgcgca cgaggattcg ctcggcaggc tgctccggca cctggtcacc
     7981 atcggcctgt tcaccgagga gaacggaacc tacggcctca ccccgctttc gcggcagctg
     8041 ctcggcgagg accaccgctg gcagcgcggc tggctggaac tcgacggtcc cggcgcgaag
     8101 atggacctcg cctacagcgg catgctgcat tcggtgcgca ccggcgaatc cgcgtacgag
     8161 tcggtgcacg gcacgccgtt ctgggccgac taccagcgcg acgagcgact gcgggtgttc
     8221 ttcggcggca tcatggccgc gcacgcctgg cagaccggcc cggcggtggc cgccgagtac
     8281 gactgggcac cggtccgccg ggtgctcgac gtcggcggcg gcatcggcgc gctgctgtcc
     8341 gaggtgctgc ggcagcatcc gcacctcggc ggcgcggtgc tcgacctgcc cccggtcgag
     8401 ccggaggcga agcaggcgct ggccgacgcc gggctcgccg agcgcgcgga gttcatcggc
     8461 ggcagctttt tcgacccgct gcccggcggt ttcgacgtgc tcatggtgtc gcgcgtgctg
     8521 accgactggg gcgacgagga cgccacccgc atcctgcgcc ggtgcgccga agccgcgagc
     8581 accgtgctca tcgtcgaagt actcgccggc gaggagcacg cgaagaacaa ctcctcgttc
     8641 gacctgcagt cgctgacgct gctcggcggg cgcgaacggt ccattgagga cttccgcgtg
     8701 ctggccgcgg ccgccgggct ggtggtgcgc acggagcgga ccgcgcccgg cggcctggtg
     8761 ctgatcgaat gcggggtggg ctgacgggct catgcccagg ccgggagccg ccgggccctc
     8821 gggtccggca gcaacccgat ctggtgcagc cggtccagcg gcgtcagcgg gtgcgagccg
     8881 agcccggaca tgttgtgcat gacggtgtag cgcagccgct ggttcgcgcc ggtgtgccgc
     8941 agcgcgcggc ggccgagcgt gcgcccggcc caggacaggt cggtgatcat gcgcgccgcg
     9001 gcgtggctgg tgcgcccgat caacgccaga tcggcctggc gacgacggtg gtacgaggcc
     9061 aggtcgccgg attcggccag cacggtggcc aggcagtcgg cgtcggcgat ggcgctgttc
     9121 atgccctgcg cggccatcgg gtgcacggcg tgcccggctt cgcctgccag cgccaggccg
     9181 ggaatccaca gcttgggcgc gaggaagcgc gcgaccggga gtacctgacg ctcgggaagg
     9241 gcggccagga tcgcgtcctc cagtggtgtc aacgcgggcg tctcgcgggc cagcgcccgg
     9301 ccccaggaaa ccaggtcgcc gccgcggagt tcgtcgggac ggacctgcgc gtacaaccga
     9361 atgcggccgc cgggcagcgg gtaacgcagg cgcagtccgc gttcggtgac gtaggcggag
     9421 aagtcggctt cgacctcggg ggcgtcgtgc agttccaggg cgaccaagcg gtgcgggtac
     9481 tcggcccggg tgatttcgat cccggcttcc ttgcgcagcc gtgaggacat gccgtcggcc
     9541 gcgaccacca gcggggcctc gatcgtgccg tccgccagtc gcacgccggt cacctgcccg
     9601 tcctggttcc gcagcagccc tttcaccagc acgccccggc ggaattcgac agtggacggc
     9661 agcgactcgg tgagcgcggt gagaatggcg gggtagtcgt gggcgagcag ccagcgatcc
     9721 ttgccgggca gcgttccgta gtccagggcc atctgcgggg ttcccgcgga atcacgggcg
     9781 accaggcgtg ccaagcggag cgcgcccgcg gactcaagtc gttgcgccac accccaggac
     9841 cgcaggatgc gcagcgagcc cggctggaag acctcgccct tcgcgaccgg cttcggtgcg
     9901 tcctgcttgt ccaccagagc cacgcgcaga ccgagattgc ccagtgcgca agccgtggcg
     9961 agacccgcca ccccggcacc gcaaacgatt gcctccgtcc tcatcggacc gcctttcggt
    10021 aacgggccag cgcccgcagg gcgaggccgt tcgccagtgc cggattcgcg taccgcgaca
    10081 cgtgccggac gtattcgttg acgcgtgccg cgggccagcc gccgccggga tcacgtgcgg
    10141 ccagcagcca gcgcaccccc ggcagcacgg aatcggcggg cgccccggcg gcgagcagcg
    10201 cgctgaccgc ccagccggtt tcctcgacgg tgccggggtc ggcgggatca ccggtgcccc
    10261 atgagccgtc ttcgtgccgg gtgcgttcca gccaggaacg ggcccggacc gccgccggtt
    10321 caccggactg cccggccttg gcgaacgtct gcagcacggc cgacgtgccc gcggtgtgca
    10381 tccggtacca gaccgattcg aagctgccgt ccggtcgttg cgccgacgcc agccagcgca
    10441 ggccgcggtg cacccgccgg tcggcggcgg gcaccccgga atcgagaagg ccgtcgagcg
    10501 cctgcgcggt catgtgcggg cacggcccgc tgttggccac cttcgtgttc cgcacgcaca
    10561 gcccccacga gccgcgcgtg tcctgttgca gcgtcagcca ggtgacaccg cgctgcacgc
    10621 tttcggcctg gtcctcgccg ggcaggtgac agagcgcgga gacgatctcg ccggtttcga
    10681 gcgtggctgg ccagccgcgg gtgcccgacc agccccagaa accaggtggg cagccgaagg
    10741 cgacgaacgg ctggtcctgt tgcagccgaa ggaaaaggtc cttggtcagg ccgagccggg
    10801 cgtcgtcgcg gtaaccggct tcgagcagcc cggccgccgc gtacatcgac cacgtcaggt
    10861 cgagtgggcc gctgttccac gagccgtcct cgttggcgtt ctcgcggaac cagcgcaccg
    10921 cgcccgcgac catgtcgtgc ccgaggtcgg cgcgggcgag gccggcgacg atcaggccgg
    10981 tcacccaggc gtcctcgcac cagccgccgg tgccgccttc gtgttcgtag acctgccgga
    11041 tgacgtcgag tgccttgggc tcagccagtt tcgagagtgc gcggtgcacg cggccgatcg
    11101 gcttgtggcg ggtttgcgcg agcccgagtg ccgacaccat gggcgcccgc aggtcgaaca
    11161 acttccggta gagaccggga agcagggcca gttcgagcgg gaaccgccgc atctcgcgcg
    11221 ggtccagcca gcccgcgaag ccgtagtact gacggcacca ggcgaccacc tcggcgtgcg
    11281 ggatggcctc caggccgccg taagcccgca gccattcctg tcccttgtgg acggcggaag
    11341 cggaattgcc cagcaggtgc aaggtggccg tggcgaccgc ggtgggtccg gcttcggaag
    11401 cctcgcccgg caccatgctc cagccgccgt cgtcggcctg ggtgcgttcc agccaggccg
    11461 cgccgcgcgc gatcaggtcc gccgatccgg tggggtcggc gaagtgcagc gcgctgaccg
    11521 cgccgaccgt gccgagtgtc gaggtgagcg cgtgctcgcc gtagtcgaac accccgtccg
    11581 gacgctgtgc cgagaacaac gcctcggccc cggtggcgat ggcttcggag agctcgtcgg
    11641 ctcggagcga ggtcatgcga cggtgtcctt tcgtcggagc agggccgggg cgggcgggat
    11701 ttcgtgccgg gctcgcatga ccgcttgcgt ggccagggaa agcacgagca ccgggaccag
    11761 cacggcgagc gcgaaggcgg gcccggcgct tccggcgacg acggccgcgg cgagcacgag
    11821 ccgttcgccg acgaggacct cgtgcgcgcg caacgcgacg gaccggtcca ccgcgtcacg
    11881 gaacaagggc gtgaaggcaa cggcacccgc gaccgcggcg agcagtacca gcgtgaggtg
    11941 cgccgacgga tccgggatga accacgccgc cgacgcgatg aacagcacgc cggtcacgta
    12001 gaggccgaga gcgagccgga ccgcgtgccg gaccccgtga cgcaccggca ccgagcggta
    12061 cccgccggcg cgatcgccgt ccacgtcccg gaccgtgccg accagattgg acgccgtgtc
    12121 gtgcgccagg aaaccgagcg cgaccgggag gaccgaccac ggtggcaacg gcaccaccag
    12181 catcgcgccg atcaccacgg cgagtgcgct caacgccccg cgcaccacat tgcccgcggc
    12241 gccgcgcttc ttgaacacct tgctgtagcc gacgatcccg agcatcgcga gcacgaacac
    12301 cggcaggatg cgccagttcg acccggccgc gagcacggcg gacgccagtg cgcacgcgat
    12361 tccgccgagc agcgcggctt ccgcggagag ccgtcccgac gggatcggcc ggtgcggttt
    12421 gccgatcgcg tcgaggccgc ggtcgaagta gtcgccgagg tagtgcccgg agagccagcc
    12481 gagcgcgggc accagcgcgg ccgtcggtgc caccggctca ccggccgccg cggcaccggc
    12541 gaggccgagc atcgcggggt aacaaagcgt gtaggggcgc caggtctgca cgtgcgcgac
    12601 ggcggccgag cgccacctcg gcccgctcac cggtcccgcc gcacggccgc ttcggcgatg
    12661 gatccgagca acgcggtcgc ttcaccggac ggaagcgtgc cgagttcggc acgcgccagt
    12721 gcgacttcct cctcggcgcg ggtacgggcg aggtccagcg cgccggtagc ggtgaccagt
    12781 tcgcggagtt cggcgagcgt ccgctccggc gggagcgcgc cgccgagaat gcgttcgagc
    12841 ggagccggac cggtctcgcg gatggcgagc agcaccggga aggtcagccg caggttggcc
    12901 gcgtcgctgg tgcccggctt gccggtgacc gacggatcgc cgaggaacgg cagcaggtcg
    12961 tcgtgcatct ggaaggcgag cccggcgtgc tcggcgaagc cggtgatcgc ggcgacctcg
    13021 gcgggcgaac cgccaccgag cagcgcgccc gcccggcacg cgccccggaa cagcgcgccg
    13081 gttttcaggg cggccatctc caggtacgcg gtcaggcagt gctccacacc ggaggcgagc
    13141 acttccttgt ccagcaaggc ttcctgcacc tggccgcggc agaggtcctc accggctccg
    13201 gccagcacct ggaccgcggc gagcaccgcg ggctccggca cgcccagcga cgcgcactcg
    13261 gcgacggcgg agaaaagacc gaggagcagg gcgtccccgg tgacgatggc gtccggggtg
    13321 ccgaagcgcg cgtgcaccgc cggacggccg cgccgcaggt cgtcgccgtc gatgatgtcg
    13381 tcgtggatca gcgacgccac gtgcaggtat tcgaccgcga gcgcggcggg cagcacctgt
    13441 tcgcgcgtgc cgccgacggc ctcggcggcg gtcaccagca gcagtggccg cagcaacttg
    13501 cccgccggga gcagggcgta accggagatc tcggcgaccc ggtgatcggt gccggaccag
    13561 cgttcgttca gcgcccgccg cacgtcctcg acggcagggg aggaggtgac ctcaccgatg
    13621 gcggtcatgc ggcgaactcc ttcgccagcg ccaggaccag gtcgttcgcc tcgggcgtgc
    13681 cggtgctcac gcgcaccccg gccccggcga tctcgcgcac cgccacgccc gcggccgcca
    13741 gatggtctac aaaggactgg ttctgcgggc ccagtcgcag ccacaggaag tttccgccac
    13801 tcggcggaac gtcccagccg aggtccagca ggcccgcgcg cacgcgatcc cgttcggtcg
    13861 cgacctcggc gcactgctcc cgcatccgag cttcggcgtc gagcgcggcg agcgccgcgg
    13921 cctgggcgag ggtgccgacc cggaagaacg gcagggtcgg ccgcagtgcg gcggccaccg
    13981 gttcgctcgc gaccaggtaa cccacacgca ggccgagcag tccgtgcgac ttggaaaagg
    14041 tccggaccac cgccacccgg tcgtcggtgg cggccagcgc caggccgtcg gcgagttcgc
    14101 cgggggaggc gaattcgcgg taggcctcgt cgatcagcac cagcacgtcc ggcggcagca
    14161 gatcgacgaa ctccgcgacc tcagcgtgcc cgagcacttc gccggtcggg ttgttcggat
    14221 tgcacagcag caccacgcgg gtttccgagg tgaccgcggc cgccagggcg cgcaggtcct
    14281 gcggttcacc gggcaccgcg accggcgtgc ccccggcgtt gccgatcagc agcgggtaca
    14341 gctcgaacga cggccagctg tgcaccaccc gcgcgccgga tccggcgtgg gcgttgagga
    14401 actgctggat cagcgcgccc gatccggcgc cggcgaccac ccgctcggcc gccacgccca
    14461 gccgccgcgc cagttccgcg gtcagcccgc cggccagcgc gtcctgggtc aggtggaccc
    14521 gatccgcgcc gtcctcgatc gcgcgccgga cgccgggcag cggcggtgaa tggttttcgt
    14581 tcaatgccag ctgatgaatg atcgggacca ttttcaccag gcctcccggt gcgatttaca
    14641 gccgtacagc agccgtcagg ctccggtgcg cccggcgcga ctgtcaagac ggccggccgt
    14701 gcttgtcctg ctttgtcctg tggtccgggg aaactaatga ttttagtaca cttcgagtgg
    14761 gaaacggggc aattcacgtg tccggttgga cggtgcggag atcgctgtct aggcttgcgc
    14821 gccgccttgt cggagctggg gttctcgcgc tctaacaaga ccttcggacg gagtagtcgg
    14881 gcgaccgcgt ccggtagtgt gctcgaaccg tgcccgcaga tcttcgtcat gtccggctgt
    14941 ccggagaatt cggttgttac gtcccggtaa acgattccgt cgaaaccgtc gagatcgggt
    15001 tcgtgtatca ggagatattc cgcgacaact gttatccggg gttcaccgcc acgatcaccg
    15061 gacggcggtg ctgagatgcg cgtggtgctg acctgcctgc cgttctattc gcacctggtg
    15121 ccggtggtgc tgccggtggc ccgcgcgctg cggcgagccg ggcacgaggt cgccgtcgcg
    15181 accgcgccgg gcatggcgtc cgaggtgacc gcggccggga tcgagcacct ggcgctgccg
    15241 aacgtgctca ccctggcgca actgctcgac cggcccgatg tcgccaccag tcccggcatg
    15301 cccggtgatc cggcgggcag cgcgcgggcg gcgacggcca gggccgagtc cgggccgctc
    15361 gccgcggcct tcgccggacc gctggccggg gtgttcgcgc gcgacctgat ccgggcatgt
    15421 gaattttgga cgcccgacct gatcgtgcgg gagtgcaacg agttcggcgg gcacttggcg
    15481 gccgagcggc tcggcgtgcg ccaggccgtg ctcgacatcg cgccgggttc cacggcgacc
    15541 ctgccgtccg tgcgggacgc gctcaacggc cagcgcgtgg aactgggcct cgccgaggtc
    15601 gacgacccgt ggtatccgaa tcggaccttc gtcgccgggt tcgtgccgcc cgggtggtat
    15661 ccggcggatc cgccgcggtg ctaccggctg ggtgagccgg acggggtgct ggacggttcg
    15721 ctcgacctgc ccgccgaccg tccactcgtg gtcgccgggc tgggcagcgt cgcggcgacc
    15781 gtggtgccgg agagcccgga actgctggaa ctgctgatca ccgcgctcgg acggctgccg
    15841 gtcacggcgg tggtcgggct cgggtccgac gcgcggcggt ggccggggtc gcggccggac
    15901 aacgtgcggc tgctggagtt cgccccgcaa cggctgctgc tggagtcggc ggagctgttc
    15961 gtctcccacg gtggtttcgg cggggtcgcc gaggccgtgc gcaccggaac gccgatggtg
    16021 gtgctgccgc tgttctccga ccagccgtac aacgccgagc gggtggcggc gctcgggctc
    16081 ggcgtccggc tcgatccggc gggactcgac ccggaagtgc tcgccgacgc gtgcgcgaag
    16141 gtgctcgacg accaggcgta ccggcggaat tcggcggcga tgtcccggcg cgcgctgggc
    16201 tgtccgggac tggaaacgct ggcggaagat ctgttcgcgc accaccgttg agccgaacgg
    16261 agcagttcac cggatgatat ttcgcgtcaa ctggctggac agtttggccc cggtgaattc
    16321 ggcgtcaggg tgaatcgtcg ataccgcccg aattcatcgg tattcttcga ccatggcttc
    16381 acggaatgtc acgaggctct tcggcatgct ggaccggccc cttggcgagc ctgaagccgt
    16441 ggcgctggcc gagcggatgt acggcgcgga cctgatcgcg gtcgcggtgc gtgagcgccg
    16501 cttcggggtc gcttcccgta ctgacgacaa tccgtacccg gcgctggaac tggctggtca
    16561 ggcctttgtc gaggtgctgg ccgaagccgg gttcacggtg aagtcgtggg agtcggtgga
    16621 gtggctttcc ggcgccgagg cgcagctgcg cgaggacacc gaggatttcg ccgagtggct
    16681 gcccgcgcca ctcgccgccc cgtgaataac aggagtaata ctgctaatgg cggcggtatt
    16741 tgtgccctgc cgtaggattc gaccatgccg ggggagagcg ccgcacagct gatcgaagcg
    16801 gctcgcgccg gtgatccgga cgctttcggc gggctcgtcg acccattccg tgacgaactg
    16861 caagcgcatt gctaccgaat gctcggttcg gtgcacgacg ccgaggacgc gctgcaggag
    16921 acactggtgc gggcctggcg cgcgctgccg aagttcgatc ccgccgcggg caccgtccgg
    16981 tcctggttgt acaagatcgc cacgaaccgc tgcctgaccg cgatcgagcg ccgcggccgc
    17041 cgcgagctgc ctgccgatct cgggcccggc gcgccggaga ccgaagtgtc ctggctggag
    17101 ccgtacccgg acgatcggct cggaccggag gcgcggtacg tggccaggga gagcgtggaa
    17161 ctcgcgtttg tcgccgcgtt gcagcacctc ggcgcccggc agcgggccgt gctcctgctg
    17221 cgcgaggtgc tggagttctc cgcgaacgag gtcgccgacc tgctggagac cagcgtcgcc
    17281 gcggtcaaca gcgcgctcca gcgggcccgc cggaccctcg atccacaacg gaccagccag
    17341 cgggcggaac tggccgcggt gggcgcggac ggcgtccgcg agctggccga ccggtacgcc
    17401 gacgcgtggc agcgcggtga tctccaggcc attgtggaca tgctcaccga ggacgccagg
    17461 tactccatgc caccgctgtt cgagtggtat tccgggcacg acggcatccg ggagttcctg
    17521 gcgagcgggc cgctgcgccg gcgctggcgg ttcgtgcccg tccgtgcgaa cggccaactc
    17581 gcctttggta cctaccgctg ggacggggac cgcgacgcct tcgtgccatc cgggctggat
    17641 gtgctcgccg tgcgcggcga ccggatcgcc gaggtcgtct cgttcctgga cgccgacttc
    17701 tcccgcttcg gcctgccgga aagcctgccg gagccggcag gtccttaggt cgcgtcgtgg
    17761 aagaccaggc cgagggtgtg ccgccggccg ctgcggaccg gggagacgcc gtgccgcacc
    17821 ggcgccgccg accagccgcg cgccgaggcc accggccggt cgcgcgtggt gaacaccagg
    17881 ccgtggccct gcgggatgag cgtcgacgtc ccgcgtgact gggctcgcgg ccgctgctcg
    17941 accagcagga actcgccgcc ggtgtggtcg gtgcccggtt cgtcgagatt gatcacgacc
    18001 tgcaacggga acaccttctc gccgtagagg tcgcggtgca acgcgttcca cccgccggtc
    18061 tcgtagcgca gcaggatggg cgtcggccgg gtctgcccgg cgtcgtggca gatccgcagc
    18121 cactcggcga gggtgtccgg ccattcggcc tcccggccga gcttggcgta ccagtcgcgg
    18181 gcgatcggca gcagccgcgg gtacagcgct tcgcgcagcg cggcgaccgg ttccgggaag
    18241 ggctcggcga agtagcggta gtcgccgtgg tcgccgaacc ggtggcggcg caggttgatg
    18301 gtggcgcgga accggtcggt ctcggtccac agcgcggcga tccggcggca ttcggcctgg
    18361 gtgagcagcc gcggcagcag agcgcagccg aggtcgccca gctcggtgcc caccgcgccc
    18421 cagtcggcgg cggccactcg tttcgcgtac ttgtccatac ccggtagacg tccgggcggc
    18481 gcgaaacgtg agacgcctct tccgttggta gaacgtgtta cagtttttcc atgatcctcg
    18541 accgattcct gctgaccgga cgggtggccg tggtgaccgg ggccggtcgc ggcatcggcg
    18601 cggcgacggc cgtggcactg gccgaagccg gtgccgacgt ggtgctcgcc gcccgcaccg
    18661 aagagcagtt gcgcgaggtc gccgggcagg tcgaagccgc gggccgcaag gcggaggtgg
    18721 tcgcggccga tctcagcgac ccggcggccg ccgccgcgct ggccgacgcg gccaccggcg
    18781 ccttcggcag gctcgacatc gtggtcaaca acgtcggcgg caccctgccg cgcccgctgc
    18841 tggagacctc gccccggttc ctcgaagagg cgttccggtt caacgtcgcc accgcgcacg
    18901 cgctgacccg cgccgccgcc ccggcgatgc tggcggccgg tggcggcgcg gtcgtcaaca
    18961 tttcgtccgc gctcggccgg gtcgccgggc gcggctacct cgcctacggc accgcgaaag
    19021 ccgcgctcgc gcactacacg cggctcgccg cggcggacct ggccccgaag atccgggtca
    19081 acgcgatcgc cgtgggcacg gtgctgacct ccgcgctcga aatcgtcgcg gccaacccgg
    19141 aactgaagga gcggatggaa caggacaccc cgttgcggcg actcggcgag cccgaggaca
    19201 tcgccgccgc ggtgctctac ctgacctccc cggccggcgc ctatctcgcc ggcaaggtgc
    19261 tcgaagtgga cggcggtctc caggcgccca acctcgacct cggcctgccg gacctctgag
    19321 gttcaggact tccagtccag cggggagcgg ctggccagcg ccgggtcgtg cttggtgaag
    19381 gtggccaggt cgccgcgcac ggtgttgtgg aaggcgtgga tcaggccgtc gcggatcagc
    19441 ttggtctgga cgccgtccac ggtgcccttc cgtggccccg ccgggacctg aagggtcgag
    19501 tcggtgtgca cgagcagcag gccgtcaccg agcgggcggc tgtcgaccag ccggatctcg
    19561 agcacgctgc cctggtagat ggtgtcgaag atcttctggt gctcgctccc gatcacctcc
    19621 cggccccgct ggatccggcc caccgcgtcg acgaagtcgg cgtcctcggc gaagtgcgcg
    19681 ccccagccgg cgccgtcacc cgcgttccag gcccgctgca ttccggagat gatctcttcg
    19741 atggtcatcg gctatcctta ctggatcgat ggtctaaaac ttggaacgac gttctaaatc
    19801 ggagcataca tggcagcgga cctgccgggc atcgtccggc tacgggatcg acgggaagcg
    19861 ctgaccctgc gcacgatcct caccgccgcg cgcggcctgt tcgccgaacg cggctacgcg
    19921 cgcaccccga tccggctgat cgcgcaggag gccggggtcg cgccgcagac gatctacgcg
    19981 cacttcggct cgaaggcggg ggtgctcggc ggcctcgtcg atttactcga cgacgaggcc
    20041 gggctgcccg acctggtggc ttcggccgag gacctgaccg atccggcgga cctgctcggc
    20101 ctgctggcga aggccagtcg tcaggtcagg gaacgctgcg gcgacatcgt ggccattctc
    20161 agctcgggcg ccgccgtcga cccggacatc gcggccaccg aggccgaggg cgcccgccgc
    20221 aaccggctgg gcgtggagat ggtgatcgag cgcatccgct cggcggggca ccgcatcgag
    20281 ccgcgggccg tcgacatcgc ggtcgccctg atgagcgcgg gggtgcacga cagcttggtc
    20341 ggcgcggcgg gctggtcgcc cgacgactac gaggactggc tgcggaaaac cctggtcagc
    20401 gcggtgctga actgaggtcg acgcgcacgg acagcaggtc cgtccccatc gcgcgcacgg
    20461 ccgcgctgtt caggcgcggc aacgacttca accgcgcgcg agcgtcgtcg tccggctcca
    20521 ggtgcgcgat ccccgagtac caccggcccc gcagccggac acgcaccgac ggatcggcct
    20581 ggatgttgcg gatgtactgc gacttctcgc cgaactccga gacgaaccag aactcgtcgc
    20641 cgacgcgccg cccaccgacc ggcgtctgcc tcggcaggcc cgacttccgg ccggtcgttt
    20701 ccagcagcac ctggaacggc aaccgccgca ggatcgggtt gccgacgtgc cgttggaacg
    20761 cggtcaccaa tcgatgcttg ttcatcggcc gggcaccttg atctcgtact gcgccatctt
    20821 gcggtagatg gtcgcacggc tcatgccgag ttcggccgcc gcgcgcacca cggtggcgcc
    20881 cggctcggtc aggcagcgca cgatctcgtc gcgttcgagc gcctgcaacc ggctcagccg
    20941 gtgcgcaccg gaactgaaca gcttggcggg caggtgccgc tggtcgacca cgtccgcacg
    21001 cgccgccgcg gtgcgggcca cgcgcttgag ctgcttgacg ttctccggcc agtggtactc
    21061 ggtcagcgcc cgcgacgcgg cggaagtgaa gctgatcggc cgtccgcgct cgcgttcggc
    21121 gaagtgcctg gccagcggca tgatgtcgtc ggggcgatgg cgcagcggcg gtgcctcgac
    21181 cacggtgtcg accaaagcgc cgagcggacc gggcagcgcg ccgaagtcct cggcggtcag
    21241 cacgaagggc tgcggccgcg cgtcgtcgtg ccggaccgag gcgaactgcc tggccagctc
    21301 tccggcggcc caggcgggca gcccgtccac accggacacg atcacgcagg tgtcgtcctt
    21361 ctccagttcg ggtgtccaca gcgtcagcca ggcgtgcaca tcttcgggag ccgggggtcg
    21421 cgcgctgagc acgcgttcgc gcggccgcgc ccggcggtgg gccatcgagg cgagcgcggt
    21481 tttcccggca cccggttcac cgaccaccgc gaccacccgc ccggccgcga gcgcggtgtg
    21541 cgcttcggcg accgcgtcgc tccacagccg cccgccgtcg gcctggggaa aacggtcggc
    21601 gtagacgtgg aacacctcgc cacgcggggt cggccgcatc cggcgcccgg ccgagcgggc
    21661 cagcatcagc gcggtggtgt tgcccgcggc ggcctgcgcc agcgccagta gcagttccga
    21721 ggacgagttc gaccaggtcg tcaggttgac gctgccggcg aggtcaccgg tgagcggatc
    21781 gagcacgggc accgccgcgc aggtgtaccc acgcaggccg gtgcagtagt gctcctcggc
    21841 ccggaccagg gtgggcgcgc gatcggccag cgccagcccg agcccgttgg tgccggcgtt
    21901 gcgctcggcg aagtagaaac ccggcgccag gtgcacccga tcgagtgaac ggttgatcga
    21961 gttgtcgttg cacaaccgcg ccagcaccag cccggcgctg tcggtgatca tcaggctgac
    22021 cggttcgttg gccagcgtcg cctgcaaccc gctgagcacc tcgtagccgc attcgtagag
    22081 cagggagccg gtgtctaccg agccggtgaa caccggcgtg acctcgtcca gtgacacgcc
    22141 gtagcgctcg ctgcgctgcc aggacgccag cagccgtggc cggtccggcg aaagttgccg
    22201 ttgctccaca tcgacctcca gtgcacgcgt cattgcgccg gtcgaagcca ggctaacccc
    22261 tcgaccggcc gattcacgcc gctcacgtgt ctcaaactga gacagccgga cgctgccgcg
    22321 ggcgtcccgg cctgcctagc gttccgtcgc agaacgtgcc gaaggcgcca cgacgcggag
    22381 gaaacccatg tacagcaagg acggcgagaa ctacttcatc gtcgacgcgc acatcgcgct
    22441 ctgggacgcc cgcccggaga accagctcaa cgtgcacggc aagcagttca tcgactgctt
    22501 ctacgactac caccggaacc tgagcccgga gtcggagctg tggccgtacg aggagtacct
    22561 ctactacggc ggcgagcggc tgatgaagga cctgttcgag gacgggtacg tcgatcacgc
    22621 catcttccag cccgcgcgcc ttggcgcgtt ctacaagaac ggcttcggcc agaccgagga
    22681 agccttcgcg ctggcgagca agcacccgga caagctgacc tacaaccact gctacgaccc
    22741 gcgcttcgag caggcgggcc tggagcagct gcgccgcgac gcggaccggt tcgggctcaa
    22801 gggcgtcaag ctctacaccg ccgagtggaa gggcgattcc cgcggttaca aactggacga
    22861 cccgtggagc taccgctatc tcgaggcgtg ccgggagctg ggcatccgga acatccacat
    22921 ccacaagggc ccgaccatcc gcccgctgga ccgcgacgcc ttcgacgtgg ccgacgtgga
    22981 ccacgccgcc accgacttca ccgacctgaa cttcgtggtg gagcactgcg gcctgccgcg
    23041 gctggaggac ttctgctgga tcgccacgca ggaaccgaac gtgcacgccg ggctcgccgt
    23101 ggcgatgccg ttcatccaca cccggccgcg gtacttcgcg cagatcatcg gtgaactgct
    23161 gtactggctc ggcgaggacc ggatccagtt ctccagcgac tacgcgctgt ggacgccgcg
    23221 ctggctggtc gagcggttcg tcgacttcca gatcccggcc gacatgaccg agtacgcgcc
    23281 gatcaccgtg gcacagaaga agaaggtgct cgggctgaac gccgccgcga tgtacggcat
    23341 cgaggtaccg gcggggctcg gcttgaaaac cccgggcctg gaaaccccgg tgggggtgtg
    23401 agcatgcggg aacggcaggc ctggcgggca ctggacgcgg tgctcgaccc cgaactcgac
    23461 gaacccatca ccgacctgga gttcgtgcgc tcgctggagg tcaccggcac gcgcgtgacc
    23521 gtccacttgc gacttccgac cgcgttctgc tcgccgaact tcgcctatct gatggcttcc
    23581 gacgccaagg acgtgctgac cgcgttgccg tggaccgagg aagtggtg
//
