LOCUS       NZ_CP045529            10852 bp    DNA     circular CON 09-DEC-2024
DEFINITION  Luteimicrobium xylanilyticum strain HY-24 chromosome, complete
            genome.
ACCESSION   NZ_CP045529
VERSION     NZ_CP045529.1
KEYWORDS    RefSeq.
SOURCE      Luteimicrobium xylanilyticum
  ORGANISM  Luteimicrobium xylanilyticum
            Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micrococcales;
            Luteimicrobium.
REFERENCE   1  (bases 1 to 4208275)
  AUTHORS   Kim,D.Y. and Park,H.-Y.
  TITLE     Genome sequence of Luteimicrobium xylanilyticum HY-24
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 4208275)
  AUTHORS   Kim,D.Y. and Park,H.-Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (23-OCT-2019) Industrial Bio-materials Research Center,
            Korea Research Institute of Bioscience and Biotechnology (KRIBB),
            125 Gwahak-ro, Daejeon 34141, Korea, Democratic People's Republic of
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2019
            Assembly Method                   :: HGAP v. 2
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 209.83x
            Sequencing Technology             :: PacBio RS
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009429125.1-RS_2024_12_09
            Annotation Date                   :: 12/09/2024 16:50:43
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,782
            CDSs (total)                      :: 3,724
            Genes (coding)                    :: 3,686
            CDSs (with protein)               :: 3,686
            Genes (RNA)                       :: 58
            rRNAs                             :: 3, 3, 3 (5S, 16S, 23S)
            complete rRNAs                    :: 3, 3, 3 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 12 of 38
            Pseudo Genes (incomplete)         :: 30 of 38
            Pseudo Genes (internal stop)      :: 2 of 38
            Pseudo Genes (multiple problems)  :: 6 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 17:46:15
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4063148
            Orig. end                         :: 4074000
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045529.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10852
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="5"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10852
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10852
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5852](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5852)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            579..1136
                     /locus_tag="KDY119_RS19375"
                     /old_locus_tag="KDY119_03643"
     CDS             579..1136
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024179.5"
                     /locus_tag="KDY119_RS19375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03643"
                     /product="NAD(P) transhydrogenase subunit alpha"
                     /protein_id="WP_083891283.1"
                     /transl_table=11
                     /translation="MTPELASSISIFVLALLVGFEVISKIPTTLHTPMMSGANSIHGVV
                     LVGAILVAGLADDPLGYVLAFLAAAFAAMNVVGGYVVTDRMLGMFRGRPSPSANAASHS
                     ASEASRSANATSHSAEASRTPEVTRRGGAETDDAKAVVGLAGAERGTSEADGRPSTSGA
                     APPRPAASPDSRRPDPDEGSDR"
     gene            1133..2611
                     /locus_tag="KDY119_RS18080"
                     /old_locus_tag="KDY119_03644"
     CDS             1133..2611
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011186906.1"
                     /locus_tag="KDY119_RS18080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03644"
                     /product="NAD(P)(+) transhydrogenase (Re/Si-specific)
                     subunit beta"
                     /protein_id="WP_153022622.1"
                     /transl_table=11
                     /translation="MSATLTITWLVYLGAAVCFVLGLHLMRSPRTARRGNALSASGMTA
                     AVLVTALLLLDEDGGGVGWHGGVWAGVALGGGIVVGGGYGLYAARRVKMTAMPQLVSLF
                     NAVGGGAAATVALADASRALAAGSWDGLSVSFSVPVALDVLIGAVTFSGSLVAAGKLQG
                     WVSGAPITFRGSRALALASAVVAVAAGVVVIVAGGGSSDGARTTASLALVVALVAALLF
                     GVLMVLPIGGADMPVVISLLNAFTGLAVAMAGFVVGNEVMIVAGALVGASGSILTKLMA
                     DAMNRSVASILVGGFGTGDAPSAAGPGGGAAATVRTVDADDVAIQLAYAHRVVLVPGYG
                     LAAAQAQHELAELANLLTSHGVAVSYAIHPVAGRMPGHMNVLLAEANVPYEQMKELEEA
                     NAELDQCDVALVVGANDVTNPAARRPGTAISGMPILDVDHARSVVVIKRSMGHGYAGID
                     NELYTDPRTGMLFADAKDGLAQLVAAVKEYVTAG"
     gene            complement(2598..2756)
                     /locus_tag="KDY119_RS18085"
     CDS             complement(2598..2756)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="KDY119_RS18085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_153022623.1"
                     /transl_table=11
                     /translation="MTRRRGHDAALPEPWERELRRMEVLARLETARTVRRAGGRPLRLT
                     ERRVTPR"
     gene            complement(2921..3286)
                     /locus_tag="KDY119_RS18090"
                     /old_locus_tag="KDY119_03645"
     CDS             complement(2921..3286)
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009777161.1"
                     /locus_tag="KDY119_RS18090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03645"
                     /product="UBP-type zinc finger domain-containing protein"
                     /protein_id="WP_036955523.1"
                     /transl_table=11
                     /translation="MAEPSGPAGDPGIDPSVPPSGPGCVECDERGGWWVHLRRCAQCGH
                     VGCCDSSPAQHASRHFQETGHPIMRSYEPGEDWWWDYRTDDYTDGPELAPPLAHPVDQG
                     APWPTDRVPENWRDLIH"
     gene            complement(3361..4092)
                     /locus_tag="KDY119_RS18095"
                     /old_locus_tag="KDY119_03646"
     CDS             complement(3361..4092)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016996598.1"
                     /locus_tag="KDY119_RS18095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03646"
                     /product="phosphotransferase"
                     /protein_id="WP_051137024.1"
                     /sec_met_domain="APH (E-value: 9e-14, bitscore: 49.7,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEEHLPGGNTTPVLRVGDTVRRAAGPWTTTIQSYLRHLRSAGMT
                     GIPEPFGVDDRGREIVSYLEGDVPHDNPGWVWGADVLDDAVLFLRRLHDASVGFAPSSP
                     GWRLPVHEPAEVVCHNDAAPYNMVFRGGRLVGLIDFDTASPGPRVWDLAYLAYWLAPYI
                     HVEGWTGDDDARTARLNRIVEVYGWDPITPTDVLRTMVSRLEELAAFTDDRAAQTGRDD
                     LAAHAVVYRRDMERIAVLAQG"
     gene            4354..4974
                     /locus_tag="KDY119_RS18100"
                     /old_locus_tag="KDY119_03647"
     CDS             4354..4974
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013347668.1"
                     /locus_tag="KDY119_RS18100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03647"
                     /product="HNH endonuclease family protein"
                     /protein_id="WP_227994431.1"
                     /transl_table=11
                     /translation="MPYVVAHARAARYPVSTAELARATRELADLPVRDRAPSDGYTREQ
                     FGQAWEDVDHNGCDTRNDVLRRDLENLTYKQGSGDCTVASGVLRDPYTGRTIDFRRGAG
                     SAAVQIDHVVALADAWQTGAQDWPAATRLAFANDPANLLAVDGPANQDKSADDASTWLP
                     PNPGYRCAYVVRQLRVKSAYGLWVTRAEHDTMARTLRTCVTVP"
     gene            complement(5001..5852)
                     /locus_tag="KDY119_RS18105"
                     /old_locus_tag="KDY119_03648"
     CDS             complement(5001..5852)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012399275.1"
                     /locus_tag="KDY119_RS18105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03648"
                     /product="family 1 encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_051137023.1"
                     /sec_met_domain="Linocin_M18 (E-value: 5e-90, bitscore:
                     298.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSNEPEVTVQPVAQVVGASNLHRWLAPVSDAAWAEIAEEASRTF
                     RRNVAGRRVVDVTGPLGLETAAANTGHVSAIEAPHEGTRSRLREVAPLVELRVPFTLDR
                     QAVDDVLRGSKDSDWQPVKDAATVLARVEDRAIFEGYEAARIGGLGPGSDNAPVAVPED
                     PRELPDAVAHAVTELRLAGVEGPYALVLDADLYTAVSETRDHGFPIRDQLERMVDSAIV
                     WAPALRGGYLLSTRGGDYELVLGQDVSIGYTSHTADSVELYLQESFTFLAYTAEASVVL
                     SR"
     gene            complement(5849..7000)
                     /locus_tag="KDY119_RS18110"
                     /old_locus_tag="KDY119_03649"
     CDS             complement(5849..7000)
                     /EC_number="1.11.1.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009884819.1"
                     /locus_tag="KDY119_RS18110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03649"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_227994432.1"
                     /transl_table=11
                     /translation="MPLNAIEGIGSAPGVAADVPEPQAVLGTLTTSSVFLVVSVRDTPG
                     ADARVLDVAADIGALVRAVGFRQSEAGLTCIVGFGSRYWDRVQPDGPRPAHLHPFRPIQ
                     GAKHDAVATPGDVFFHVRANRADLVFELTRLLMDALGDDVQVEDHTVGFRYFDSRDLLG
                     FVDGTENPTGRDAAAAAIVSLDDEPDFAGGSYVVVQKYVHDLAAWHAMPVEEQERVIGR
                     TKLDDVELDDDVQPSNSHVTLNTIVDENGEEHDVLRDNMAFGDPSTGEYGTFFIAYADD
                     PSVTELMLERMFVGAPVGNYDRILDVSTAVTGSLFFVPSLELLESLAEGDDPTVTSADL
                     ERIAREADGRSSPPAPSAPVSTDGDATRPHDDLRIGSLREEPQ"
     gene            complement(7044..7514)
                     /locus_tag="KDY119_RS18115"
                     /old_locus_tag="KDY119_03650"
     CDS             complement(7044..7514)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020017397.1"
                     /locus_tag="KDY119_RS18115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03650"
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="WP_036955518.1"
                     /transl_table=11
                     /translation="MSTETVVAALDAAGIPYELTQHARARSLVEAAELQGVEPSRIVKT
                     LVVRRGEDDYLFVLVPGDRTISWPKLRALLGVSRLSMPDAGVAKDVTGYERGTITPFGA
                     SRAWPVVADERVDGTISLGGGAHGVGVRLAADDAVRALGATVADVTDEVPTS"
     gene            complement(7547..10579)
                     /locus_tag="KDY119_RS18120"
                     /old_locus_tag="KDY119_03651"
     CDS             complement(7547..10579)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014600.5"
                     /locus_tag="KDY119_RS18120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="KDY119_03651"
                     /product="PASTA domain-containing protein"
                     /protein_id="WP_153022625.1"
                     /transl_table=11
                     /translation="MQSRTTRRQPGAAARRGSVVVAVVAAASLGALGAASAQGLGSPVP
                     AGTSSVPAAAPVTTGGGTTGGGTTGVGASVTTAPDVTTAPASVLDRDDVLAILNRADDY
                     LAAHPDAVGGPVAQAASETGMLLVTYDAQVAATAALTPPVDLPVSALEPPDPLTTSPWD
                     KAVAKTSGDTDAADDAAPTADPAAPASTESTAPTSTASPSSTSSPTLPSDGATTGVLAA
                     DGAAPTGLLPPTGTTPTGSATDAPAAADTPQANPTSPAGAVDDGATGALIPDPATTAVQ
                     GSMPSVDEPTSPAVAVPGATPTPTPTASVPSSAPTSVPTAEPTSPAGTVPAPSDDVTTA
                     PGATPTTSADGSVPTANAPTDEGTPSTTPTPSATPTPSTTAPAALPTPSATATPDTGTD
                     SSGVDGSSSVGTGASAAGGIPSTTTDSLADPDAQDGSEPVTWDDVVAAAERLATALDAA
                     TAAQSAAGTTGTGVVGGDGVAATTAPLTGGLANQLTQLVDRYGTSIDGYKNGEIPASAL
                     CPLDFAPGQMLRCDAANRLEALSKLFEKRFGHPIPITDSYRPLAVQIELRRTKPNLAAV
                     PGTSNHGWGLAVDLGYPISTGRSAEYAWLREHGPAYGWDNPAWGHLDGSKPEPWHFEFH
                     TGGLLPTGTPVIDYTGVTVPSDTEAGPKAPSDHATAPKTSKPGAATVVVPKGLVGHSFA
                     TVQKKLEGLGLKVAKPTKAYSATVKAGAVVRVTPGSGSKVKAGSTVRAVVSQGPKPATT
                     VTIPDGLVGQPLATVQKKLTGLGVKVVVDPKKVYSDAVKVGSVASVSPAEGTSVKVGST
                     VTLVVSQGSKPPATVTISDGLVGQPLATVQKKLTGLGVKVVVDPKKVYSDAVKAGSVAS
                     VSPAEGTSVKVGSTVTLVVSQGPKPPATVTIPEGFVGQDPDTIKDKLVALGLKVVIADV
                     EETSDAPAGTVAGLTKDDGTELAEGSQVEAGSTVTIVVSSGQDGSVPTPTPTGTPTTEP
                     TGSTSEPTATPTEKARESETD"
     misc_feature    10610..10625
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
ORIGIN
        1 ggcacggccc ggcggctcgg cgcgcaggtc acgggctacg acatccgccc gtcctcggcc
       61 gacgaggtcc ggtcgctcgg cgcgacgttc ctccggctga cgagctcccc cgagggcgcg
      121 ggcgagggtg gctacgcgcg cgagctcacc gacgacgagc gtgccgccca acagaccgag
      181 ctcgccgggc acgtcgcgaa gttcgacgtc gtcatcacga cggcgcaggt cccgggccgc
      241 cgcccgcccg tcctcgtcac cgccgagacg gtggccgcga tgcggccggg gagcgtcgtc
      301 gtcgacctcg gcgcaagcga cctgggcggc aacgtcgagg gatcggtgcc cgacgagcgc
      361 gtggtcaccc cgggcggcgt gaccgtcgtc ggggcgggca acctcgcctc cgagctcccg
      421 acggcggcgt catccgcgta cgcgcgcaac gtcgcggcgg tgctgcgcgc ggccgtccgg
      481 gacggccggc tcgacgtcga cgtggacgac gacgtgatcc gagcgatccg cgtccctgcc
      541 gccacctcca acccagcccc agccgaggag gcgcgcgcat gaccccggag ctggcgtcgt
      601 cgatcagcat cttcgtcctc gccctgctgg tcgggttcga ggtcatcagc aagatcccga
      661 cgaccctcca caccccgatg atgtcgggcg cgaactcgat ccacggcgtc gtcctggtcg
      721 gcgcgatcct cgtcgcggga ctcgccgacg accccctcgg ctacgtcctg gccttcctgg
      781 ccgcggcctt cgccgcgatg aacgtggtgg gcggctacgt cgtcacggac cgcatgctgg
      841 gcatgttccg cggcaggccg tcaccctcgg cgaacgcagc gtcacactcg gcgagcgaag
      901 cgtcacgctc ggcgaacgca acgtcacact cggcggaggc gagccggacg cccgaggtga
      961 cgaggcgagg cggggcggag accgacgatg cgaaggccgt ggtggggctg gcgggagccg
     1021 agcgaggaac gagcgaggcg gatggtaggc cgagcacgtc gggcgcagcc ccgcctcgcc
     1081 ccgccgccag ccccgactcc cgccgccccg acccggacga aggcagcgac cgatgagcgc
     1141 gacgctgacg atcacgtggc tcgtctacct cggcgccgcg gtgtgcttcg tcctcggcct
     1201 gcacctgatg cgctcccccc gcacggcacg ccgcggcaac gcgctgtcgg cgtcgggcat
     1261 gaccgcggcg gtcctggtga cggcgttgct gctgctggac gaggacggcg gcggggtcgg
     1321 ctggcacggg ggcgtctggg cgggggtcgc gctgggtggc gggatcgtcg tcgggggcgg
     1381 gtacggcctg tacgcggcgc ggcgcgtcaa gatgacggcg atgccgcagc tggtgtcgtt
     1441 gttcaacgcg gtggggggcg gcgcggcggc gacggtcgcg ctggcggatg cgtcgcgcgc
     1501 gctggcggcg ggctcgtggg acgggttgtc ggtgtcgttc tcggtgccgg tcgcgttgga
     1561 cgtcctgatc ggtgcggtga cgttctcggg ctcgttggtc gcggcgggca agctgcaggg
     1621 gtgggtgtcg ggggcgccga tcacgttccg cggttcgcgg gcgctcgcgc tggcgtcggc
     1681 ggtggtcgcg gtcgcggcgg gcgtggtggt gatcgtggcg ggcggcggct cgtccgacgg
     1741 tgcccggacg acggcgtcgc tcgcgttggt cgtggccctg gtcgcggcgt tgctgttcgg
     1801 ggtgctgatg gtcctgccga tcggcggcgc cgacatgccg gtcgtgatct cgctgctgaa
     1861 cgcgttcacg gggctcgcgg tggcgatggc ggggttcgtc gtcggcaacg aggtcatgat
     1921 cgtggcgggt gcgctcgtag gggcgtcggg gtcgatcctg acgaagctca tggcggacgc
     1981 gatgaaccgg tccgtcgcgt cgatcctggt gggcgggttc ggtacgggtg acgcgccgtc
     2041 ggcggcgggc ccgggcggcg gcgcggcggc gacggtgcgc acggtggacg ccgacgacgt
     2101 cgcgatccag ctcgcgtacg cgcaccgggt ggtcctggtg ccgggctacg ggctggctgc
     2161 ggcgcaggcg cagcacgagc tcgcggagct ggcgaacctg ctgacgtcgc acggcgtggc
     2221 ggtgtcgtac gcgatccacc cggtcgccgg ccgcatgccg ggccacatga acgtgctgct
     2281 cgcggaggcg aacgtgccgt acgagcagat gaaggagctc gaggaggcca acgcggagct
     2341 cgaccagtgc gacgtcgcgc tggtggtggg agcgaacgac gtcacgaacc cggcggcccg
     2401 ccgcccgggc acggccatct cggggatgcc gatcctcgac gtcgaccacg cgcgctccgt
     2461 cgtcgtgatc aagcggtcga tgggccacgg gtacgcgggc atcgacaacg agctctatac
     2521 ggatccccgg acgggcatgc tgttcgcgga cgcgaaggac ggtctcgctc agctcgtcgc
     2581 ggcggtgaag gagtacgtca ccgcggggtg acgcgacgtt ccgtgagtcg cagcgggcgt
     2641 cccccggcgc gacgcaccgt gcgtgccgtc tcgagtcggg ccaggacctc catgcgacgc
     2701 agctcgcgtt cccacggttc gggcagcgct gcgtcgtgcc ctctgcgcct cgtcatgact
     2761 gccatctacg tcccctgccc ttaccgacgc cttctcgtcc gaggcgtccc ggttcccgtc
     2821 gttgtggacg gcgccttccg ggggcgccgt cgaaggaaga gagcgccggc ctcgctctcc
     2881 gtgacggccg tgaccaggtg agattcgggt gaagacgcgg tcagtggatc aggtcgcgcc
     2941 agttctcggg gacacggtcc gtgggccagg gcgcgccctg gtcgacgggg tgggcgagcg
     3001 ggggcgccag ctcggggccg tccgtgtagt cgtcggtccg gtagtcccac caccagtcct
     3061 cgcccggctc gtaggaccgc atgatcgggt gcccggtctc ctggaagtgc cggctcgcat
     3121 gctgcgcggg cgagctgtcg cagcagccca cgtgcccgca ctgggcgcac cggcgcaggt
     3181 gtacccacca gccgccgcgc tcgtcacact cgacgcaacc ggggccgctc gggggcacgc
     3241 tcggatcgat gccggggtca ccggccggtc cactcggttc tgccacgggg gcctcctctc
     3301 gacctgctta ccgtaggccg aggcgccgac ggcggcagca tggaccgggc tcccgccctc
     3361 tcagccctgc gcgaggaccg cgatgcgctc catgtcgcgc cggtacacca cggcgtgcgc
     3421 ggcgaggtcg tcccggccgg tctgcgcggc ccggtcgtcc gtgaacgcgg cgagctcctc
     3481 gagccgggag accatggtgc gcagcacgtc cgtcggtgtg atcgggtccc agccgtagac
     3541 ctcgacgatc cggttcagcc gggccgtccg cgcgtcgtcg tcacccgtcc agccctcgac
     3601 gtggatgtac ggagcgagcc agtacgccag gtacgccaga tcccagaccc gtggccccgg
     3661 tgacgcggtg tcgaagtcga tgagcccgac gagccgcccg ccccggaaca ccatgttgta
     3721 cggggccgcg tcgttgtggc agacgacctc ggcgggctcg tggacgggca ggcgccagcc
     3781 tggcgacgac ggcgcgaagc ccaccgaggc gtcgtgcagg cgccgcagga acaggacggc
     3841 gtcgtcgagg acgtcggcgc cccacaccca gccagggttg tcgtgcggca cgtcgccctc
     3901 gaggtacgag acgatctccc gcccgcggtc gtcgacgccg aacggctcag ggatgccggt
     3961 catgcccgcg gaccgtaggt ggcgcaggta ggactggatc gtcgtggtcc acgggccggc
     4021 ggcgcggcgc acggtgtcgc cgacacgcag gacgggcgtg gtgttgccgc cgggcaggtg
     4081 ctcttcgatc atcgcgaccc atcgtgcccg acaacgctgc attcgtgaac tcggccgctc
     4141 cgcacgaacg gcgccgcgac gcacgacgcc gcctctgggg acgcggcccg tcgtgcacag
     4201 gcgccgttcc ctgaccgccg tcgcagcacg cccctccggc aggctcggcc cgtgccgcgt
     4261 cctcgtcccg cccctcgccc tcgtgcccga cgacgcacgc gcgccgcctg cgcgctcgtc
     4321 ctcctagcgg ccgtggtcgc ggcggcgacg ggcgtgccct acgtcgtcgc gcacgcccgg
     4381 gcggcgcgct acccggtctc cacggcggag ctggcgcggg cgacgcggga gctggccgac
     4441 ctccccgtgc gggaccgtgc gccgtcggac ggctacacga gggagcagtt cggccaggcc
     4501 tgggaggacg tggaccacaa cggctgcgac acgcggaacg acgtgctccg gcgcgacctc
     4561 gagaacctca cgtacaagca agggagcggc gactgtacgg tcgcgtccgg cgtgctgcgc
     4621 gacccgtaca ccgggcgcac catcgacttc cgtcgcggcg ccggctcggc cgccgtccag
     4681 atcgaccacg tcgtcgcgct cgccgacgcc tggcagacgg gcgcccagga ctggcctgcc
     4741 gccacccgcc tcgcgttcgc caacgatcct gcgaacctgc tcgccgtcga cggcccggcc
     4801 aaccaggaca agagcgccga cgacgcctcc acgtggctcc cgccgaaccc cggctaccgg
     4861 tgcgcgtacg tcgtccggca gctccgcgtg aagtccgcgt acggcctgtg ggtcacccgt
     4921 gccgagcacg acacgatggc ccggaccctg cggacctgcg tcaccgtccc gtgacggccg
     4981 cccgcgcgcg ccgtcgccgc tcagcgcgac aggacgaccg acgcctccgc cgtgtacgcg
     5041 aggaacgtga acgactcctg caggtacagc tccaccgagt ccgccgtgtg cgacgtgtac
     5101 ccgatggaca cgtcctgccc cagcaccagc tcgtagtcgc cgccccgcgt cgacaacagg
     5161 tacccgcccc gcagggccgg cgcccacacg atcgcactgt ccaccatgcg ctcgagctgg
     5221 tcccggatcg ggaacccgtg atcccgcgtc tccgacaccg ccgtgtacag gtcggcgtcc
     5281 agcaccaggg cgtacggacc ctcgaccccc gccaaccgga gctcggtgac ggcgtgcgcc
     5341 accgcgtccg gcagctcccg cggatcctca ggcaccgcca cgggcgcgtt gtccgacccc
     5401 ggccccaggc ccccgatccg cgcggcctcg tagccctcga agatcgcccg gtcctcgacc
     5461 cgtgccagca ccgtcgccgc gtccttcacc ggctgccagt cggagtcctt cgagccccgc
     5521 agcacgtcgt ccaccgcctg ccggtcgagc gtgaacggca cccgcagctc cacgagcggc
     5581 gcgacctcgc gcaaccgcga ccgcgtcccc tcgtgcggcg cctcgatcgc cgacacgtgg
     5641 cccgtgttcg ccgcggccgt ctccagcccc agcgggcccg tcacgtccac cacccgacgc
     5701 cccgccacgt tccggcggaa cgtgcgcgac gcctcctccg cgatctcggc ccatgccgcg
     5761 tcgctcaccg gcgcgagcca gcggtggagg ttggacgccc cgacgacctg cgccaccggc
     5821 tggaccgtca cctcgggctc gttgctgctc attgcggttc ctctctcagg ctgccgatgc
     5881 ggaggtcgtc gtgcggtcgg gtcgcgtcgc cgtcggtgct gacgggggcg gacggggcgg
     5941 gagggctcga cctgccgtca gcctcgcgtg cgatccgctc caggtccgcg gacgtgaccg
     6001 tcgggtcgtc gccctcggcc agggactcca ggagctcgag cgacgggacg aagaacaggg
     6061 agcccgtgac ggccgtggag acgtcgagga tccggtcgta gttgccgacg ggggcgccca
     6121 cgaacatccg ctcgagcatc agctcggtca ccgacgggtc gtcggcgtac gcgatgaaga
     6181 acgtcccgta ctcgcccgtc gacgggtccc cgaaggccat gttgtcgcgc aggacgtcgt
     6241 gctcctcgcc gttctcgtcg acgatggtgt tgagggtgac gtgcgagttc gacggctgga
     6301 cgtcgtcgtc gagctcgacg tcgtcgagct tcgtgcggcc gatcacgcgc tcctgctcct
     6361 cgaccggcat cgcatgccat gccgcgaggt cgtgcacgta cttctgcacg acgacgtagc
     6421 tcccgcccgc gaagtccggc tcgtcgtcca gcgagacgat cgcggcggcg gccgcgtccc
     6481 gtcccgtcgg gttctccgtc ccgtccacga accccagcag gtcgcgcgag tcgaagtagc
     6541 ggaacccgac ggtgtggtcc tcgacctgca cgtcgtcgcc cagcgcgtcc atgagcaggc
     6601 gggtcagctc gaagacgagg tcggcacgat tggcgcggac gtggaagaac acgtcccccg
     6661 gtgtcgcgac agcgtcgtgc ttggcgccct ggatcggccg gaacgggtgc aggtgtgccg
     6721 ggcgtggccc gtcgggctgc acccggtccc agtaccggga cccgaacccg acgatgcacg
     6781 tcagtcccgc ctccgactgc cggaaaccga ctgcccgcac cagcgcgccg atgtcggccg
     6841 cgacgtcgag cacgcgggcg tccgcacccg gcgtgtcccg cacgctcacg acgaggaaga
     6901 cggacgaggt ggtgagggtt cccagcacgg cttgcggctc gggcacgtcc gcggcgaccc
     6961 cgggcgcgct gccgatcccc tcgatcgcgt tcagtggcac ggcacgagcc tttcacgtgc
     7021 gacgacgtgg tgcacccgtg ccgtcacgac gtgggcacct cgtccgtcac gtcggcgacc
     7081 gtcgccccca gggcacggac cgcgtcgtcc gcggccaacc gcacgccgac cccgtgcgcg
     7141 ccgccgccca gcgagatggt gccgtcgacg cgctcgtccg cgaccaccgg ccacgcgcga
     7201 ctcgcgccga acggggtgat ggtgccgcgc tcgtacccgg tgacgtcctt cgcgaccccc
     7261 gcgtccggca tcgacagccg cgagaccccg agcagcgcac ggagcttcgg ccacgagatc
     7321 gtccggtcgc ccgggaccag gacgaacagg tagtcgtcct ctccccggcg cacgacgagc
     7381 gtcttcacga tccggctcgg ctcgacgccc tggagctcgg ccgcctccac gagcgaacgg
     7441 gcgcgtgcgt gctgcgtcag ctcgtaggga atcccggcag cgtccagcgc ggcgacgacg
     7501 gtctcggtgc tcatgtcacc gagcgtaggt ggtgcgcacc gacccgtcag tcggtctcgg
     7561 actcccgagc cttctcggtg ggcgtggccg tgggttcgga ggtgctgccg gtcggttcgg
     7621 tcgtcggggt gcccgtcgga gtcggggtcg ggacgctgcc gtcctgcccg gacgagacga
     7681 cgatcgtcac cgtcgaaccc gcctcgacct gggagccttc ggccagctcc gttccgtcat
     7741 ccttcgtgag gccggcgacc gtccctgccg gcgcatcgga cgtctcctcg acgtccgcaa
     7801 tcacgacttt cagcccgagg gccaccagct tgtccttgat cgtgtcggga tcctgcccca
     7861 cgaagccctc cgggatcgtc accgtcgccg gcggcttcgg cccttgggac accacgagcg
     7921 tgacggtcga gcccaccttc accgaggtgc cctcggcagg cgacacgctc gccaccgagc
     7981 ccgccttcac cgcgtccgag tacaccttct tcggatcgac gacgaccttc acacccagcc
     8041 cggtgagctt cttctgcacc gtcgcgagcg gctgccccac gaggccgtcc gagatcgtca
     8101 ccgtcgccgg cggcttcgac ccttgggaca ccacgagcgt gacggtcgag cccaccttca
     8161 ccgaggtgcc ctcggcaggc gacacgctcg ccaccgagcc caccttcacc gcgtccgagt
     8221 acaccttctt cggatcgacg acgaccttca cacccagccc ggtgagcttc ttctgcaccg
     8281 tcgcgagcgg ctgccccacg aggccgtccg ggatcgtcac ggtggtcgcg ggcttcggcc
     8341 cctgggacac gactgccctg acggtcgaac cggccttgac cttgctgccc gaccccgggg
     8401 tcacgcgcac gaccgcgccc gccttcacgg tggccgagta ggccttggtc ggcttcgcga
     8461 ccttcaggcc gaggccttcg agcttcttct ggacggtcgc gaacgagtgc cccacgaggc
     8521 ccttcggtac cacgacggtc gctgcgccgg gcttcgacgt cttcggcgcg gtcgcgtggt
     8581 ccgacggggc cttcggcccg gcctcggtgt cggagggcac ggtcacgccc gtgtagtcga
     8641 tgaccggggt gccggtcggg agcaggccgc cggtgtggaa ctcgaagtgc cacggctccg
     8701 gcttgctgcc gtcgaggtgc ccccacgccg ggttgtccca gccgtacgcg ggcccgtgct
     8761 cgcgcagcca cgcgtactcc gcggaccgcc cggtggagat ggggtagccg aggtcgacgg
     8821 cgagccccca gccgtggttc gacgtgccgg gcacggcggc caggttgggc ttcgtcctgc
     8881 ggagctcgat ctgtacggca aggggccggt aggagtcggt gatcgggatc gggtgcccga
     8941 acctcttctc gaaaagcttg ctcagggcct cgagccggtt cgcggcgtcg caccgcagca
     9001 tctgccccgg ggcgaagtcg agcgggcaca gcgcggacgc ggggatctcg ccgttcttgt
     9061 acccgtcgat gctggtcccg taccggtcga cgagctgcgt gagctggttc gcgaggccgc
     9121 ccgtcaacgg tgcggtcgtc gcagcgaccc cgtccccgcc gacgacgccc gtgcccgtcg
     9181 ttcctgcggc gctctgagcc gcagtggcgg catcgagggc ggtggcgagc cgctcggccg
     9241 cggcgacgac gtcgtcccac gtgaccggct ccgacccgtc ctgcgcgtcg gggtcggcga
     9301 gcgagtccgt ggtggtggac gggatcccgc cggcggccga cgccccggtc cccaccgacg
     9361 acgacccgtc gacccccgac gagtccgtcc ccgtgtcggg cgtcgccgtg gccgacggcg
     9421 tggggagcgc ggccggagcg gtcgtcgacg gggtgggggt cgccgacggg gtgggggtgg
     9481 tcgacggggt gccctcgtcc gtcggggcgt tcgcggtcgg gacggatccg tcagcgctgg
     9541 tcgtgggggt cgcgccgggg gccgtggtca cgtcgtccga gggcgcgggg accgtgcccg
     9601 ccgggctcgt aggctccgcc gtcggcacgg acgtgggcgc cgaggacggg acgctcgcgg
     9661 tcggcgtcgg cgtcggggtc gctcccggaa cggcgaccgc ggggctcgtc ggctcgtcca
     9721 ccgagggcat gctgccctgg accgccgtcg tggccgggtc cgggatcagt gcgccggtcg
     9781 cgccgtcgtc gaccgccccc gcggggctcg tcgggttcgc ctgtggcgtg tccgcagccg
     9841 ccggggcgtc ggtcgcagag cccgtcggcg tcgtgccggt cggcggcagc agacccgtcg
     9901 gggcggcacc gtccgcggcc aggacccccg tggtggcacc gtcgctcggc agggtcgggg
     9961 acgacgtgct gctcgggctc gcggtgctcg tgggcgcagt gctctcggtc gacgccggtg
    10021 cggccgggtc cgcggtcggc gcggcatcgt cggcggcatc cgtgtcgccg gaggtcttcg
    10081 ccaccgcctt gtcccacggc gacgtcgtca gcgggtccgg cggctcgagc gcgctgaccg
    10141 gcaggtcgac cggcggcgtg agcgcagcgg tcgcggcgac ctgcgcgtcg taggtgacca
    10201 ggagcatccc ggtctcgctc gccgcctgcg ccacagggcc gccgaccgcg tcggggtggg
    10261 cggcgaggta gtcgtccgcg cggttcagga tcgcgagcac gtcgtcacga tcgagcacgg
    10321 atgcgggggc cgtcgtgacg tccggcgcgg tcgtcacgct cgcgccgacg cccgtcgtgc
    10381 cgccacccgt cgtgcctcca ccggtcgtga ccggcgcggc cgccgggacg gacgacgtcc
    10441 cggccgggac ggggctcccg aggccttgcg cgctcgcagc tcccagggca ccgagcgagg
    10501 cagcggcgac gactgcgacg acgacgctcc cacgccgcgc cgcggctccc ggctgcctgc
    10561 gcgtggtgcg gctctgcatg actcccctgg tggacgtggc gtcgcgcccg gtgaccgcgg
    10621 tcacacgtgt ggcgcccttc ccagcctgcg ccatcttcgc ggcgtgcgct acatcgcgtc
    10681 ccacgaagag caccctacgt cctcgagatg actgcgtgac aacgctgcca tcccgaagag
    10741 ttcacccggt ggccaccggg ccgctgacac ccgggccgct gacaccgggg ccgcacaagc
    10801 gaccctcgta gatcccgatc ttcgcgtcga tcgcgcgcag gtgctcccgc gt
//
