LOCUS       NZ_CP045178            21167 bp    DNA     linear   CON 25-NOV-2024
DEFINITION  Streptomyces tsukubensis strain AT3 chromosome, complete genome.
ACCESSION   NZ_CP045178
VERSION     NZ_CP045178.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces tsukubensis
  ORGANISM  Streptomyces tsukubensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8615214)
  AUTHORS   Cao,G., Zhong,C., Fu,J., Zhang,P., Liu,M. and Zong,G.
  TITLE     Complete genome sequence of Streptomyces tsukubaensis AT3
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8615214)
  AUTHORS   Cao,G., Zhong,C., Fu,J., Zhang,P., Liu,M. and Zong,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2019) Shandong Medicinal Biotechnology Center,
            Shandong First Medical University, 18877 Jinshi Road, Jinan 250062,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-OCT-2019
            Assembly Method :: SOAPdenovo v. OCT-2019; SPAdes v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 997.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009296025.1-RS_2024_11_20
            Annotation Date                   :: 11/20/2024 08:40:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,005
            CDSs (total)                      :: 6,919
            Genes (coding)                    :: 6,691
            CDSs (with protein)               :: 6,691
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 76 of 228
            Pseudo Genes (incomplete)         :: 184 of 228
            Pseudo Genes (internal stop)      :: 10 of 228
            Pseudo Genes (multiple problems)  :: 38 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:10:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8168001
            Orig. end                         :: 8189168
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045178.1.
            Bacteria and source DNA available from Dr. Guangxiang Cao.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21167
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="indole"
                     /region_number="36"
                     /rules="(indsynth or dmat or indole_PTase)"
                     /tool="antismash"
     cand_cluster    1..21167
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(indsynth or dmat or indole_PTase)"
                     /kind="single"
                     /product="indole"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21167
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:11167](+)"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11167
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(indsynth or dmat or indole_PTase)"
                     /neighbourhood="10000"
                     /product="indole"
                     /protocluster_number="1"
     gene            complement(556..>1000)
                     /locus_tag="GBW32_RS33715"
                     /old_locus_tag="GBW32_33710"
                     /pseudo=""
     CDS             complement(556..>1000)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1097: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377534.1"
                     /locus_tag="GBW32_RS33715"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="GBW32_33710"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="KVHLAGDSNVRPLAIVLTTGQAGDSTAFTTVMADIQVPRTDLGRP
                     RTRPDAVLADRAYSSRAIRVHLRGRHIRAVTARRPGPPPPTTWPPVRQGTCFRRRVPQG
                     TQHRRAVHRSLQAVARPGHANGQARHRLPGRTPPRSEPHPGPAV"
     misc_feature    complement(1127..1142)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.67"
                     /tool="antismash"
     gene            complement(1900..2391)
                     /locus_tag="GBW32_RS33720"
                     /old_locus_tag="GBW32_33715"
     CDS             complement(1900..2391)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GBW32_RS33720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="GBW32_33715"
                     /product="hypothetical protein"
                     /protein_id="WP_227025403.1"
                     /transl_table=11
                     /translation="MARVPVLSSRPMRGFTWRAKQRHRPGLEVMASTGRGHGFESLEEV
                     RLLVALDLVGASEVLSQPFRLDFTHKGGSSWHIPDYLAVISDGTWLLDVRPMGLIKDED
                     ALKYAAAREVAAACGWRYRVRQRRPLRRGRQGGRHPPHEETEPDLRAPGHHPPPRKMAG
                     "
     misc_feature    complement(2233..2235)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    2522..2535
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.84"
                     /tool="antismash"
     gene            complement(2850..3401)
                     /locus_tag="GBW32_RS33725"
                     /old_locus_tag="GBW32_33720"
     CDS             complement(2850..3401)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018488459.1"
                     /locus_tag="GBW32_RS33725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33720"
                     /product="EF-hand domain-containing protein"
                     /protein_id="WP_077973701.1"
                     /transl_table=11
                     /translation="MTTTAQDITTVKLERTFDQMDADKDGHLDWSDYQKLADRYIQGYN
                     LAKDDRRTRALQTFCQIYWLELLRHAGVDGDRLTKDQFVTANRLAVIDTSRLNVTEGGG
                     HAIFDVIDADGDNEISKDEFARLMRDVWKYNSTATMDLFYKLDTDGDGAISRHEFIRAV
                     REHFLSNDPDAPGSIFFGHI"
     gene            3653..3814
                     /locus_tag="GBW32_RS36140"
     CDS             3653..3814
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GBW32_RS36140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_193386007.1"
                     /transl_table=11
                     /translation="MKNQDVHRWCFYEKPFFEEGGRTREVGKFENVKDLGFQARSARQE
                     ACQNGGED"
     gene            complement(4134..4904)
                     /locus_tag="GBW32_RS37930"
     CDS             complement(4134..4904)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039623.4"
                     /locus_tag="GBW32_RS37930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF5995 family protein"
                     /protein_id="WP_227025616.1"
                     /transl_table=11
                     /translation="MRDPGSSAQCFHAGYRRSAGAGDGLARSPRNRRTARPRQHGGRDP
                     RRLCAAPGCGRGVGGELGLDDIAGVRVVEACQRLHEPPASRSRRPTCRSDPRPAHSRRD
                     ERVGLSPRRSRQPPGTPPRTEGAAPRPRVGAGQGRRTAESSAVHQDYEHVNDLLAGTEE
                     VRTEFETQIVKIAARDVELLKHAVASFSITAAREAAWSAARSLWNDKKGVVPRVYSAHE
                     TGLGETAGTVSHGIRLPVAPDSPHNPVTGRMAGP"
     misc_feature    5499..5514
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.86"
                     /tool="antismash"
     misc_feature    5528..5542
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.41"
                     /tool="antismash"
     gene            5735..6934
                     /locus_tag="GBW32_RS33735"
                     /old_locus_tag="GBW32_33730"
     CDS             5735..6934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005328.1"
                     /locus_tag="GBW32_RS33735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33730"
                     /product="ATP-binding protein"
                     /protein_id="WP_077969003.1"
                     /transl_table=11
                     /translation="MTNFWQDPTVWALTAGVPVATAVVVRQRKTIRVLRRQKQGVEEDL
                     GALQGSYAHLESTLEELRRGYDEVVRQAKEEAENATNTVLKSAMQTLQGLAAEQQRVIS
                     GLQSTYGDSAVLQDLLDVDHMNAQFNRRAQSIAVLCGGWLGRQRGAASVYDVIRGAQGR
                     IRHYQRVEVLSQVDFAVTSRAVEPLALTVAELLDNATSYSAPSSMVEINVRTVPRGICI
                     VIDDAGVGMSEEEKTNASALMSSESAVSVSELGNPPAFGFAVIGALCARFGFTVTIDST
                     SPYGGVRAVVMVPKDLLTDTPEPRKPSAALAADSGSRSNGSAPVETSDGLPRRRNKRAM
                     ALVSDTQPVPPPPSARSAEARVAAMGAFQRGTVDGRSARGPAVERDPSPADSHKGTDAP
                     "
     gene            6955..7341
                     /locus_tag="GBW32_RS33740"
                     /old_locus_tag="GBW32_33735"
     CDS             6955..7341
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552722.1"
                     /locus_tag="GBW32_RS33740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33735"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_077969136.1"
                     /transl_table=11
                     /translation="MLEDALAIPHALHAVLISADGLQMSRTADIGRDEADKVAAAVSGL
                     QSLSRAVAFFCGDDSLNNWRQTLIEFDGGWVFLNAAGGGSFLAVAASADVDMGDITYRM
                     QQLVGRLGKAMSTGRRDDTVSAHD"
     gene            7334..7717
                     /locus_tag="GBW32_RS33745"
                     /old_locus_tag="GBW32_33740"
     CDS             7334..7717
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552723.1"
                     /locus_tag="GBW32_RS33745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33740"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_077969004.1"
                     /transl_table=11
                     /translation="MTDPGRFEPESEAGELVRPYVITRGRTLPDENEFSLITLVTTATD
                     ERQRPQRLSPEEQQVLEMCSSGYLSVAEIAAHSQLPLGVVKVLLSALAEGGYLVTRAPV
                     PSARLANTTLLQEVLDGLKALPV"
     misc_feature    7379..7381
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7692..8297
                     /locus_tag="GBW32_RS33750"
                     /old_locus_tag="GBW32_33745"
     CDS             7692..8297
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013005331.1"
                     /locus_tag="GBW32_RS33750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33745"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_077969005.1"
                     /transl_table=11
                     /translation="MVSRPSLSEDAYVRSGAEQTAVKILVVGHFAVGKTTLIGSLSEIT
                     PLSTEEHMTSLSESVDDLKGVQGKTTTTVALDFGRLTLSERIVLYLFGSPGQQRFVNLW
                     DDMARGALGALILVDPERLADSFEVMDLIETYGLDFAVAINAFDGGAEHTPEAVREALD
                     LLPDTPVVTIDARDKKSSVNALITMVRYLQKRAALEHA"
     gene            8294..9649
                     /locus_tag="GBW32_RS33755"
                     /old_locus_tag="GBW32_33750"
     CDS             8294..9649
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552725.1"
                     /locus_tag="GBW32_RS33755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33750"
                     /product="cytochrome P450"
                     /protein_id="WP_077969006.1"
                     /transl_table=11
                     /translation="MTTPSVPPPGCPAHGSGRRISLDTPEFAADPHAFYRYMRQSGPTA
                     AVTIAPGVDATLVTDYSAALELLQDPGTFRKDSRRWRDLNEGRVNPDSPVLPLLSYRPN
                     CMFTDGAEHLRLRQAITESFARISNSRLSKIVNQAARFLISQFSARGSADLLRDYAQQL
                     PLYVFNELFGCPAEIGDRVLFGISGMFDGVNAEQASQVLAQAVGELVALKRAQPGEDIT
                     SYLLQHSAQLTNEELVHTLVLLLGAGGEPEGNLIGNGFYTMLTNEEYARNGQFDKALDD
                     TLWRNPPMSNYAPHYPVADTDVGGDKVRAGELLLVSFGAANTALADRGADTRGHLAWSA
                     GPHACPSKEPARLIALTGLETLFNALPDVELAVPADSLVWRPGPFNRALTSLPVRFGAV
                     TPRPAAQPQPTAVPHHQQVHQPVAPRPAAPQAAGGKSGRGGWSGFVRWLTGQ"
     misc_feature    complement(9663..9678)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.36"
                     /tool="antismash"
     gene            10001..11167
                     /locus_tag="GBW32_RS33760"
                     /old_locus_tag="GBW32_33755"
     CDS             10001..11167
                     /GO_function="GO:0016765 - transferase activity,
                     transferring alkyl or aryl (other than methyl) groups
                     [Evidence IEA]"
                     /GO_process="GO:0009820 - alkaloid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) indole:
                     indole_PTase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010358092.1"
                     /locus_tag="GBW32_RS33760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33755"
                     /product="tryptophan dimethylallyltransferase family
                     protein"
                     /protein_id="WP_077969007.1"
                     /sec_met_domain="indole_PTase (E-value: 1.6e-118, bitscore:
                     394.4, seeds: 22, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSRPETGIPTGGPGEGTLGDHVLGQLRRLGATVGLSEADTELYG
                     QVLLDSLPGAAGRPLTLPPASPSFISDDHTPVEFSLASTSDAAPVLRVLVEPGYGHSTM
                     ADSARAGVDAIRAMAARWDFSTDQLDALGDLFLPASAEGPLALWYALDLRAGGVPGVKV
                     YLNPSAAGTEHAARTVREALRRLGYGEAFAKLPPAAGYPFVALDLGTWKTPRVKVYVSH
                     PRMSADDASALSRSSGAAEADIRYFFHATAGSLLPTQRGGDDTLRLLRRPALTCHSFTQ
                     GDAEPSGFTLHIPVRDYVRDDEEAVTRAAALLTRFGMDPSILNRGLRALTRRQLADGAG
                     LIAYLALVYERNQRPRITAYLSSEAYAVRPPHERYPQDERVPADLSSS"
     misc_feature    10409..10411
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    10763..10765
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11226..12599
                     /locus_tag="GBW32_RS33765"
                     /old_locus_tag="GBW32_33760"
     CDS             11226..12599
                     /NRPS_PKS="Domain: Beta_elim_lyase (41-419). E-value:
                     3.5e-76. Score: 248.2. Matches aSDomain:
                     nrpspksdomains_GBW32_RS33765_Beta_elim_lyase.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552727.1"
                     /locus_tag="GBW32_RS33765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33760"
                     /product="tryptophanase"
                     /protein_id="WP_077969008.1"
                     /transl_table=11
                     /translation="MEPYRIKVVEPIAFTTRAEREDALRRVAYNPFDLRADEVTIDLLS
                     DSGTGAISAEQLAAGMNGDESYAGSRSFYRWHEVVSELTGYPHILPAHQGRAAERILFS
                     SLLRPGTSVLSNTHFDTTRANVELTGCQAYDLPCAEAKDLDSDYPFKGNIDLTALERAL
                     ENAHEAPVAAVLMTITNNGGGGQPVSMENLHRTAALCRRHAVPLILDAARFAENAWLVT
                     QREPGYEGRTPRQVAEEAFRLADGCVMSAKKDGIVHIGGFIGLKDPELAERCQGLLIAT
                     EGFTTYGGLAGRDLDMMARGLLEVTEPAYLAERADIAGYLAARIREAGVDIVEPAGLHA
                     LYVNAGRLLPHIPPHQYPGTALACELYLRGGIRSAELGSLYLGEEDEQGNPTRTAPYEL
                     VRLALPRRVYTRSHYDHVANTLADIAKNPESVHGYRIVGQSPILRHFSIKLESVRSGN"
     aSDomain        11349..12482
                     /aSDomain="Beta_elim_lyase"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GBW32_RS33765_Beta_elim_lyase.1"
                     /evalue="3.50E-76"
                     /label="GBW32_RS33765_Beta_elim_lyase.1"
                     /locus_tag="GBW32_RS33765"
                     /protein_end="419"
                     /protein_start="41"
                     /score="248.2"
                     /tool="antismash"
                     /translation="DLLSDSGTGAISAEQLAAGMNGDESYAGSRSFYRWHEVVSELTGY
                     PHILPAHQGRAAERILFSSLLRPGTSVLSNTHFDTTRANVELTGCQAYDLPCAEAKDLD
                     SDYPFKGNIDLTALERALENAHEAPVAAVLMTITNNGGGGQPVSMENLHRTAALCRRHA
                     VPLILDAARFAENAWLVTQREPGYEGRTPRQVAEEAFRLADGCVMSAKKDGIVHIGGFI
                     GLKDPELAERCQGLLIATEGFTTYGGLAGRDLDMMARGLLEVTEPAYLAERADIAGYLA
                     ARIREAGVDIVEPAGLHALYVNAGRLLPHIPPHQYPGTALACELYLRGGIRSAELGSLY
                     LGEEDEQGNPTRTAPYELVRLALPRRVYTRSHYDHVAN"
     gene            complement(12730..13029)
                     /locus_tag="GBW32_RS37155"
     CDS             complement(12730..13029)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024736.5"
                     /locus_tag="GBW32_RS37155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transposase"
                     /protein_id="WP_077969009.1"
                     /transl_table=11
                     /translation="MSRHFTGHGPGPGPRRIPPRAARTGPGAAAGVHDLRDIVNAFLYG
                     DRSGIAWEYPPHDFPPSNTVYDSYAQWEADGVAERVPFEAAGCDGVLLDAPKRW"
     misc_feature    complement(13356..13370)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 17.44"
                     /tool="antismash"
     misc_feature    13375..13388
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: medium, score: 22.13"
                     /tool="antismash"
     gene            13375..14289
                     /locus_tag="GBW32_RS33775"
                     /old_locus_tag="GBW32_33770"
     CDS             13375..14289
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978746.1"
                     /locus_tag="GBW32_RS33775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33770"
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="WP_077969010.1"
                     /transl_table=11
                     /translation="MSQINIARPNAPTYDELVPSRYALKVGDIDVMVISDGVLPIPAVT
                     MATNAPAADLAAWLKDMFLPPETLDWPLNVAVVRSGGRTILVDSGLGTEFPGFPRAGQL
                     AMRLDAAGIDPASVTDVVLTHLHMDHIGGLLVDGLRGRLRPDLRVHLASAEAEFWEAPD
                     FSRTAMPTPVPDVLRTTASRFLDVYRSQLRPFEKEYEVAPGVLISRTGGHTPGHSIIRL
                     ESGGDRLTFAGDAVFQPGFDCPDWHNGFDHDPEESARVRIRLLNELAARGEQLVATHLP
                     FPSICRVAVAGDAFRFVPAVWDY"
     gene            complement(14686..15942)
                     /locus_tag="GBW32_RS33780"
                     /old_locus_tag="GBW32_33775"
     CDS             complement(14686..15942)
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1094: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018384019.1"
                     /locus_tag="GBW32_RS33780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33775"
                     /product="globin domain-containing protein"
                     /protein_id="WP_077969137.1"
                     /transl_table=11
                     /translation="MLSSPSAPIVRDTLRTVGASLGTITELFYTRMFEERPDLLRTLFN
                     RANQANGAQREALAGAVAAFATALVTHPEERPDAVLGRIANKHASLGITSEQYTLVGRH
                     LLGAVKEVLGDAVTPAVAAAWDEVYWLMANALIAMEARLYAEAGVENGVVWRDMEVAER
                     TEESPDTASFVLRRPDGLPTDPFLPGQYISVQVELPDGARQIRQYSLSTSPRHKNWRIT
                     VKRESSADGHVPEGEVSSWLHAHARAGRTLKVSLPFGDLVLLDGEGPLLLASAGIGITP
                     MLSMLDHLASVSPDRPVVIIHADRSPTDHAHRLELSELVGRLTRASLHLWYENGVGERY
                     GTVAGEPGELERERETHVVRVREGRADISDLTLPQNTTAFLCGPLPFMRTVRGDLLTHG
                     LSPAAIHYEVFGPDLWLSK"
     misc_feature    complement(14959..14961)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(16195..16803)
                     /locus_tag="GBW32_RS33785"
                     /old_locus_tag="GBW32_33780"
     CDS             complement(16195..16803)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131898.1"
                     /locus_tag="GBW32_RS33785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33780"
                     /product="hypothetical protein"
                     /protein_id="WP_077969011.1"
                     /transl_table=11
                     /translation="MSVTHAAHHIEVTAESLQDDLARLEVQKQSLERELAAVVAHLSSV
                     QRALGALQVLMSPAGPGIPHTTDTPGAPPRTAEAAAHGEPARPAKEPHDATSTAAPTAT
                     SSAGNAHQEHSPARPEDHDAAPESSDKESARKNYGRLTEQILHYFAEVGDVDVRARDVA
                     AALGRATDSGSINAVRSTLDRLVGSSRIRRTGRGLYRAV"
     misc_feature    complement(16939..16953)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: weak, score: 20.26"
                     /tool="antismash"
     gene            complement(17134..18030)
                     /locus_tag="GBW32_RS33790"
                     /old_locus_tag="GBW32_33785"
     CDS             complement(17134..18030)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016430945.1"
                     /locus_tag="GBW32_RS33790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33785"
                     /product="RNA polymerase sigma-70 factor"
                     /protein_id="WP_077969012.1"
                     /transl_table=11
                     /translation="MHTGDGTDSLDQATKDFLAVRPRLFGIVYRVLGSAVEAEDIVQDV
                     WLRWQKTDRADILEPSAFLTTITTRLAINFAQSARVRRESYVGPWLPEPVSTSADPQVG
                     AERAEALDLAVLFLLEKLNPVERAAYVLREAFEYPYRRIAEILETTEANTRQLVSRARK
                     HLSAQRKERVSPADHRRLLEVFLNAARHGNLAELEQILATDVVSYSDGGGVRGASKIPV
                     VGRTHVSRYLVAFAPRFWPRAQSRWTEANGRPAVLISTAGKAVALLSLDVSAEGIDRIM
                     WVMNPAKLSSYAASLEG"
     gene            18239..18687
                     /locus_tag="GBW32_RS33795"
                     /old_locus_tag="GBW32_33790"
                     /pseudo=""
     CDS             18239..18687
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006131873.1"
                     /locus_tag="GBW32_RS33795"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33790"
                     /product="cupin domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MSDTHAGHAHAAGAPAASDSWLTAAQVLQDAAPLTIPEGASAMTI
                     QVEWEPGDPGTPPHRHSGPAFGYVVEGAVRFELEGEPERWSRPAARSGSLAAT"
     gene            complement(19111..19584)
                     /locus_tag="GBW32_RS33800"
                     /old_locus_tag="GBW32_33795"
     CDS             complement(19111..19584)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010982226.1"
                     /locus_tag="GBW32_RS33800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33795"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_077969013.1"
                     /transl_table=11
                     /translation="MDARLDFFGNTLGAKVLKHLNSANKVVSDSTLPHTTQELVKIRAS
                     QINGCGFCTDMHTKDADHAGETAQRLHLIATWREATVFTEAERAALELAEQGTRTADAA
                     GGVGDEAWANAVKHFDEEQLAALISLIAVINAYNRVNVINRTPAGGYRPGQFG"
     gene            19653..19802
                     /locus_tag="GBW32_RS36145"
     CDS             19653..19802
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="GBW32_RS36145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_179120189.1"
                     /transl_table=11
                     /translation="MGRVSCVTLAKCARRAALEARFPGLLPSSLLTPVAESAGGHTTPG
                     AEGP"
     misc_feature    19967..19978
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: medium, score: 16.85"
                     /tool="antismash"
     gene            20197..20937
                     /locus_tag="GBW32_RS33805"
                     /old_locus_tag="GBW32_33800"
     CDS             20197..20937
                     /NRPS_PKS="Domain: Abhydrolase_1 (3-90). E-value: 2e-09.
                     Score: 29.3. Matches aSDomain:
                     nrpspksdomains_GBW32_RS33805_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009999534.1"
                     /locus_tag="GBW32_RS33805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_33800"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_077969014.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.5e-13, bitscore:
                     50.5, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.1e-05, bitscore: 23.9,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAILIHGVPDTHQVWDGVRRELTRTDVEAWNLPGFGAPRPEGFT
                     SAKKEYVDWLIDRLERVGEPVDLVGHDWGCILTARVASLRPDLVRTWAGGNGPVNAEYV
                     WHPLAKTWQHPVEGARFMSELEPDSFAHDVAAGFDVPVDLAREMAGRVGEAMKDSVLGL
                     YRSAVTMGEEWEPGLARVTAPCLVFWGVLDPACPIGFGEKLAVSLRAPEVVRLDCNHWP
                     LLQKPGEVAAAIEAHWKSPTDQVS"
     aSDomain        20206..20466
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GBW32_RS33805_Abhydrolase_1.1"
                     /evalue="2.00E-09"
                     /label="GBW32_RS33805_Abhydrolase_1.1"
                     /locus_tag="GBW32_RS33805"
                     /protein_end="90"
                     /protein_start="3"
                     /score="29.3"
                     /tool="antismash"
                     /translation="ILIHGVPDTHQVWDGVRRELTRTDVEAWNLPGFGAPRPEGFTSAK
                     KEYVDWLIDRLERVGEPVDLVGHDWGCILTARVASLRPDLVR"
ORIGIN
        1 ctccggcgtc taccgcatct tcaccagcag cgccgactcc acggcgcagt acctcactgc
       61 ccaggaaagc ggtgtgaccg ttctgccttg ggggtccgtg cccgcaaggg agcaggagtt
      121 cagggtggag gtcatcgagg acggcgtcgc cgccatccag agtcccgcca atctgttccc
      181 ttcgcgttcc gtgagttaca aggagccgga gaagggcgag agggtgatcc tggggccgat
      241 gagtgacttc cccacccgcg agtggaagat caccaaggat acgaagcagg gaaccttcac
      301 catcggcgtc gcaggtggcg gagagtctct ggtactggcg ctggctcaga ttccgatctt
      361 cccgcttccg ctcgaactgg cgacctccga cagggctctt gtctggacgt tcgagctcgt
      421 cgaacagggc tgacaaccgc gcggcgtccg gttgaggaaa ccgtccccat tcgcatcgcg
      481 tgcggtgtca tgaagcacat cggtgccggc tcgccgcctg cggacgcgcg tggggttctc
      541 gatcgctgac ggcggttacc gccgggcccg gatgaggttc gctgcgaggt ggagtgcggc
      601 ctggtaggcg atggcgagct tgtccgttcg catggccagg ccgcgccact gcttgaagcg
      661 accgatgcac cgctcgacgg tgttgcgttc cttgtgggac tcggcgtcga aaacaggtgc
      721 cctgccgcac tgggggccac gtcgttggcg gtggcggacc tggcctgcgg gctgtgacag
      781 cacggatgtg acggcctcgc aggtgaacgc ggatcgcgcg ggaggagtac gcgcggtcgg
      841 cgagcaccgc gtctggccgg gtccggggtc gtcccaggtc ggtgcgcggg acctggatgt
      901 cggccatgac ggtggtgaac gcggtggagt caccggcctg tccggtagtg agcacgatcg
      961 ccagcggacg gacgttggag tcgccggcca ggtggacctt gagggtggac caaggcagtt
     1021 gcccggcccg cgaggacacc gacggaggca tcaccgcagc caccacggcc gacctgtacg
     1081 ttctcgacat ccgacagatg tcttggcggt gactcccgca aaggtgctga ccagacggtg
     1141 tcggcgattc tgaccatcga ccggtcgacc cggcccgcga gatctgcgtc ggcctgaacc
     1201 ggggggctgg aaactgtgaa gcccgcacag caccggtccg gggcccatac gcgtatccgc
     1261 ggggccggat gttgatgcac gcgatgcgat gcggtacatc accccaggcc cacccagaag
     1321 gcagcgtgga actgccggaa gctgccccga caggaggaag ggcagcatcc cggtacgcag
     1381 ggacaacggc ctgccggggg tctcggtgat gcccaggccg gcgcttcacc cgtggtccgg
     1441 gttggctggc cggtcagctg ttgaagcggg gccggccggg gccccggtgt ggaggccgtc
     1501 atcgggagcc gcggcgcgcg ggcgcagggg catcagggcc ccgggcaccg gcggcgggca
     1561 cccctcaggg gcaactggcg ggcaggccgt gctgtggggg cgccgaggga agaggggcgt
     1621 gacgagccgg cggttcgcac ggggactcca gctggcgcag accgctggcc ccacccaccc
     1681 ctcgccacaa tgtccacacg tccgcaaaac cgcccctggg cattgcaaga agttggtgcc
     1741 atccgtcctc gcccacggcg cacgggttga agcgagagct gccctacggt gcgtttcatg
     1801 tccctggtga gaaaccctca gatgcggacg gggggttctt gcgtgcccag tggttgccag
     1861 atccagtcgg caacgccgcg gtatgttcct ccggtgcttt catccggcca tcttgcgcgg
     1921 cggaggatgg tgacccggtg ctcggaggtc aggttccgtt tcttcatggg gcggatgtcg
     1981 accgccttgc cgtcctcgcc gaagggggcg tcgttgacgt acgcggtacc gccagccgca
     2041 cgcagccgcc acctccctgg ccgccgcgta cttcagcgcg tcctcgtcct tgatcaatcc
     2101 catcgggcgc acgtccagca gccacgtccc gtcgctgatc acggccaagt agtccgggat
     2161 gtgccaggac gacccgcctt tgtgcgtaaa gtccagccgg aacggctgcg acagcacttc
     2221 cgaggccccc actaagtcca gcgcgaccag cagccgcact tcctccagcg actcgaagcc
     2281 gtgccccctg cccgtggacg ccatcacctc caggccgggc cggtgccgct gcttcgcccg
     2341 ccatgtgaac ccccgcatcg gccgcgacga cagcaccgga acacgagcca tgtcgcggac
     2401 cggccggcag acctcgccag cacccacccg ccacgtcgaa ctccaccgac aaatccagcc
     2461 atcagcgaga tcgagttgat tccgaaatgc ggcatccccg ctgtacacct cgacaagctg
     2521 atcgaggcgg atcgagtccc atcggatgcc cgccctggct cttctcgctc gctcacccac
     2581 agcatcacca cccgcgtggc gacaaggccc gatcttcgga actgaccaca acacagcgtt
     2641 acggaagcaa gatccgccaa ctaccgcgct cgtccgccaa gtagagaaat ctcgtgacct
     2701 gttgtaggga aggttgagtg gataccccgt gtgtggcgtg gtgccttgga gtcggtagtg
     2761 cggacggcgg cggccgcccg ctggaagtgg gtccaggggc ggccgtggga ggctgaccga
     2821 aggccggcgg gcgcctcgaa gccggtgggt cagatgtggc cgaagaagat gctgcccggg
     2881 gcgtcggggt cgttggagag gaagtgctcg cgcaccgcgc ggatgaactc gtggcgggag
     2941 atcgccccgt ccccgtcggt gtccagcttg tagaacaggt ccattgtcgc cgtcgagttg
     3001 tacttccaga cgtcccgcat cagacgggcg aactcgtcct tgctgatctc gttgtcaccg
     3061 tcggcgtcga tgacgtcgaa gatcgcgtgg ccgccgccct cggtcacgtt gaggcggctg
     3121 gtgtcgatga ccgcaaggcg gttggcggtg acgaactggt ccttggtgag ccggtccccg
     3181 tccacgcccg cgtggcgcag cagctccagc cagtagatct ggcagaaggt ctgcagcgcc
     3241 ctggtccggc ggtcgtcctt ggcgaggttg tacccctgga tgtagcggtc cgcgagcttc
     3301 tggtagtccg accagtcgag gtggccgtcc ttgtcggcgt ccatctggtc gaaggtgcgc
     3361 tcaagcttga cggtggtgat gtcctgcgcc gtagtggtca tgggtatccc tttttcttga
     3421 tcacatctgt tgacctgttc agcgtcggcc acagccctcc accaggggcc gaaataccca
     3481 gttcatcacc cgatctagtg agcacctccg gttcggcacg cgtgcctgat ccggctgctg
     3541 ggccacgccg agcggcggac catccagagc atcaccatcc gcgtggcgac aaggcccgat
     3601 cttcggaact gaccacaaca acgaggagcc gcagatcccg cccacgcgga gcgtgaagaa
     3661 ccaggacgtc caccgctggt gtttctacga gaagccgttc ttcgaggagg ggggccggac
     3721 gcgtgaggtc gggaagttcg agaacgtgaa ggacctcggg ttccaggccc gctccgccag
     3781 gcaggaggcc tgccaaaacg gcggggagga ctgagtcagg tcctggacgg gagcggacga
     3841 ggtgcccggc agtgcgccgt agaggcccgt accggttcgc ggtatccggt gcgggcccct
     3901 tgccactgtg cggatgacct gagcgctttc gcccggtcgg gcccccgtcg cggtgcatgg
     3961 ccgatatgtg ggagggcgcg cttccctccc cgaggttcag tggccttcag cagcacaacc
     4021 gcggccccga ccgccacatg ggggttgcga acgggaccac agcgggtctg tacggggccg
     4081 acggccgctg ttgtgtacac gggcagaatg ccgcggacga ggtcggcggc cgttcacggc
     4141 ccggccatcc ttcccgtgac cggattatgc ggagagtcgg gggccacggg cagccggatg
     4201 ccgtggctga cggtgccggc tgtctccccg agaccggttt catgagcgct gtagaccctg
     4261 gggacgacac ctttcttgtc gttccacagg gaccgcgcgg cgctccaggc ggcttcgcgg
     4321 gcggcggtga tggagaagct ggcgacagcg tgcttgagga gttcgacatc ccgggcggcg
     4381 atcttgacaa tctgggtctc gaactcggta cgaacctcct cggtgcctgc cagaaggtca
     4441 ttgacatgct cgtagtcctg atggaccgct gacgattcgg ccgtacgccg accttgtcca
     4501 gccccgacgc gtggcctcgg tgcagcgcct tcagtacgcg ggggagttcc aggaggttgg
     4561 cggctgcggc gcggtgaaag gccgacgcgt tcgtctctgc gtgaatgagc gggacgcgga
     4621 tcggatcggc aggtcggtct tcttgagcgg cttgccggcg gttcgtgcag gcgctggcaa
     4681 gcttctacga cgcggacgcc ggcgatgtcg tccaggccga gctcgcctcc aacgccgcgg
     4741 ccgcagcccg gggctgcgca gagccgcctc ggatcgcggc ccccgtgctg ccgaggtcga
     4801 gctgtccttc gatttctcgg cgaccgggcg aggccgtccc ccgcacccgc tgatcgcctg
     4861 tatccggcat ggaagcactg tgctgagctg ccgggatccc tcatgacgca gcagggtccc
     4921 ggcagggcag gctggccagt tgtcaccttg ccttcatcca cgccggcaga cctcggtggt
     4981 ggtccggaac ctccgcacga cgacggaccg ccccgacaaa ccgatcccgc cgggttcacg
     5041 gggtgcgcgc tgcgcgagac gccactcctc ggcgctcagc gaggcgctcg ccctcaacgt
     5101 gcctgacatc gcgcttctgc tcacccggcc accctcgcgc accgccacgt cccccacttc
     5161 ggcgacggtc cggtccccac cgcggcgacg gtccggtccc cgcccggcga cggtccggtt
     5221 cccgcccggt gggcggctcg cccacgacct cgctccgtcc gtgccactcg ggcggcgatc
     5281 cgtgtgagct ccaggggaac gcggccgtcg gacccgggtc gcggccttat aaatcggcca
     5341 tcctgcgccg tgcggaaggc cgccgtccgg gcctcttctc ggaaatccgc gctccgccgc
     5401 gtcgaccggt tcttgggcga ggacacgttc gtcgtgtcgt gggaggccgc gcgtacctgg
     5461 ccggacagct cgccgcgccg ccgaacgtgc acaccggtac cacactttct tcactgatct
     5521 caacaactat tttccgccaa tgaggctgcg gcgcgtcgta cttgacagag cctcatgatc
     5581 gtccggtgat acgattttgg gcacatgcca cgtgggcttt ctcctccgat gagggctaca
     5641 gccaagggct ctccgggggt gaaggctgcc cgcagccgag ggtccgcatg gacagattcc
     5701 gagagctgaa ttccagccgc tcaaagagag tcacatgacg aatttttggc aggatccgac
     5761 agtctgggcg cttactgccg gcgtccctgt cgcgaccgcg gtagtcgttc gccagcgaaa
     5821 aacgatccgg gtgttgcgcc gtcagaagca gggcgtcgaa gaggatttgg gcgcactgca
     5881 gggcagttat gcccacctcg aatcaaccct cgaagagctg cggaggggct acgacgaggt
     5941 ggtacgacag gccaaggagg aggcggagaa cgccacaaat accgtactga agtccgcgat
     6001 gcagacgctc cagggcctcg cggcggagca gcagcgggtc atctccgggc tgcagagcac
     6061 gtacggtgac tcggccgtgc tgcaggatct actggatgta gaccatatga acgcccagtt
     6121 caaccgacgc gcgcagtcca ttgccgtgtt gtgcggaggg tggctcggca ggcagcgggg
     6181 ggcggcatcg gtctatgacg tgatccgcgg cgctcagggc cgtatccggc actaccagcg
     6241 cgtcgaggtc ctgtcgcagg tcgacttcgc ggtgaccagc cgggcggtcg agccgctcgc
     6301 gctgacggtg gccgaactgc tcgacaacgc caccagctac tcagcgccgt cgtccatggt
     6361 cgagatcaac gtgcggacgg tacccagggg tatctgcatc gtgatcgatg acgccggcgt
     6421 cgggatgagc gaggaggaga agacgaacgc ctcggccctc atgtccagtg agtccgcggt
     6481 gagcgtctcc gaactcggca acccgcccgc gttcggtttc gcggtgatcg gtgccctgtg
     6541 tgctcgcttc gggttcacgg tcaccatcga cagcacctct ccctatgggg gcgtccgtgc
     6601 ggtggtgatg gtgccgaagg atctgctgac cgatacgccg gagccgagga agcccagcgc
     6661 agcgctggcg gccgactccg gttcgagaag taacggttct gctcctgtgg agacatctga
     6721 cgggctgccc aggcgaagga acaagcgggc catggcgctc gtgtcggaca cgcagcccgt
     6781 cccgcctccg ccgtccgccc ggtcggcgga ggcaagggta gcggctatgg gcgcctttca
     6841 gcgtggcacc gtcgacggcc gaagtgcgag ggggccggcc gtcgaacgtg atcccagtcc
     6901 tgccgattca cacaaaggaa ccgatgcccc gtgagtagcg acgacctgtc ctggatgctt
     6961 gaggacgcgc tggccattcc gcacgccctc cacgcggtcc tgatctctgc cgacggcctg
     7021 cagatgtccc gcacggcgga catcggccgg gacgaggccg acaaggtcgc cgctgccgtg
     7081 agtgggttgc agtctctcag ccgggccgtc gcgttcttct gcggtgacga cagcctgaac
     7141 aactggcgcc agacactcat cgagttcgac ggcggctggg ttttcctgaa cgcggcgggt
     7201 ggcggctcct tcctcgctgt ggcggcttcg gccgatgtcg acatggggga catcacttac
     7261 cggatgcagc agctcgtcgg caggctgggc aaggcgatgt cgaccggccg tcgcgacgac
     7321 acggtcagcg ctcatgactg accccggccg tttcgagccc gagtccgaag ccggggaatt
     7381 agtccggccg tacgtcatca cccgcggacg caccctgccc gacgagaatg agttctcact
     7441 catcaccctc gtcacgacgg ccacggacga gcgacagcgt ccccagcggc tctctcccga
     7501 ggagcagcag gtcctggaga tgtgttcgag cggctatctt tcggtcgctg agatcgccgc
     7561 gcactcccag ctacctctcg gcgtcgtcaa agtcctgctc agtgccctcg ccgagggggg
     7621 ctatctggtc acccgtgcgc cggtgccctc ggctcgactc gccaacacaa ctcttcttca
     7681 ggaggtgctc gatggtctca aggccctccc tgtctgagga cgcatacgtg cgcagcggtg
     7741 cagagcagac tgcggtgaaa atcttggtcg tcgggcattt cgcggtcggc aagaccacct
     7801 tgatcggctc tctctccgaa atcacgccgc tgtccaccga agagcacatg acgagcctct
     7861 ccgagtcggt ggacgatctc aaaggagtac aggggaagac caccaccacc gtcgccctgg
     7921 acttcggtcg cctgacactc agtgagcgca tcgtgctcta cctgttcggg tcaccgggac
     7981 agcagcggtt cgtcaatctg tgggacgaca tggcccgcgg agcgctcggc gccctgatcc
     8041 tggtggaccc cgagcggctg gcggacagct tcgaagtcat ggatctgatc gagacctacg
     8101 gcctcgactt cgctgttgcc atcaacgcat tcgacggcgg cgcggagcac acacccgaag
     8161 cggttcggga agcgctcgac ctgctgcccg acaccccggt cgtcaccatt gacgcacgcg
     8221 acaaaaagtc gtccgtgaac gcactgatca ccatggtccg ctacttgcag aagcgcgccg
     8281 ccctggagca tgcatgacaa ccccctccgt acctccgccc ggctgccccg cacacggcag
     8341 cggccggcgc atatccctcg acacaccgga gttcgccgcc gacccgcacg cgttctaccg
     8401 gtacatgcgt cagtccggcc ccacagcggc cgtcaccatc gctcccggag tggacgcgac
     8461 cctggtgacg gactacagcg cagcactcga acttctgcag gacccgggca ccttccgcaa
     8521 ggactcacgc cggtggcgtg acctcaacga gggccgcgtc aaccccgaca gcccggtcct
     8581 gcccctgctg tcctaccggc ccaactgcat gttcactgac ggcgccgagc acctgcggct
     8641 gcgtcaggcc atcaccgaga gcttcgcccg catcagcaac agccggctga gcaagatcgt
     8701 caaccaggct gcccgcttcc tcatctccca gttcagcgcg cgcggctcgg ccgacctgct
     8761 cagggattac gcgcagcagc tgcccctgta cgtgttcaac gaactcttcg gctgtccggc
     8821 ggagatcggc gaccgcgtgc tgttcgggat ctccggcatg ttcgacggag tcaacgccga
     8881 gcaggccagc caggtcctgg cccaggcggt cggcgagctg gtggcgttga agcgcgccca
     8941 gccgggtgag gacatcacgt cctacctgct gcagcattcg gcacagctga ccaacgagga
     9001 gctggtgcac acgctggtgc tgctcctcgg cgcgggcggt gagccggagg gcaacctcat
     9061 aggcaacggc ttctacacca tgctgaccaa tgaggagtac gcgcgcaacg gacagttcga
     9121 caaggcgctc gacgacaccc tgtggcggaa cccgcccatg tccaactacg cgccgcacta
     9181 cccggtcgcc gacacggacg tgggcggcga caaggtgcgc gccggtgagc tgctactggt
     9241 gagtttcggt gccgccaaca cagcgctggc ggaccgagga gccgacacgc gcgggcacct
     9301 tgcctggagc gcgggtccgc acgcgtgccc gtcgaaggag ccggccaggc tcattgccct
     9361 gacgggcttg gagaccctgt tcaacgcgtt gcccgacgtc gaactcgcgg tccccgcgga
     9421 cagcctcgtc tggcggcccg gcccgttcaa ccgggccctg acgtccctgc ccgttcgctt
     9481 cggggcggtc acaccgcgtc ctgcggccca gcctcagccg acggccgtgc cacaccacca
     9541 gcaggtgcac caacctgtcg cgcccaggcc tgcggcaccg caggccgccg ggggcaagtc
     9601 ggggcggggc ggctggagtg gcttcgtgag gtggctgaca ggtcagtagc cgtcaaacgc
     9661 actgtgacgc agatgacaca ggcggttgct gtagcccgca tgaaagatca actactgggg
     9721 taggactgcg cggagtgtct ggagtgacac acgatgaagg agaggcagtg ggacccgaag
     9781 caacctccgc gcaacgttct gcacacaagc ggccggacca acggcgcact actgccagtg
     9841 gaaagagacc gtgcgggggc ggcgaccccg acgaaccaca tggccggaca gccgcctctc
     9901 ccggcggttc tctttttgtc tcttcgtccg ccggaacatc acgctcccgt acccccgcgc
     9961 cctgcgaacg ctctcagcgc ctcgaagcgc ggggggcgcg atgacctccc gtccggagac
    10021 cggcataccg acaggcggcc ccggagaggg aacgctcgga gaccacgttc tcggtcaact
    10081 gcggcgcctc ggcgccacgg taggcctgag cgaggcggac accgagctgt acgggcaggt
    10141 cctgctcgac tccctcccgg gcgccgccgg gcgaccgttg accctgccgc cggcttcacc
    10201 cagcttcatc tccgatgacc acacaccggt cgagttctcc ctcgccagca cgtcggacgc
    10261 cgctccggta ctgcgggtgc tggtggagcc cgggtacggc cacagcacca tggccgacag
    10321 cgctcgcgcc ggggtcgatg ccatccgcgc gatggctgcc cgctgggact tctccaccga
    10381 ccaactcgac gccctgggcg acctgttctt acccgcttcg gccgagggac cactggccct
    10441 gtggtacgcg ctcgacctgc gcgccggggg agtccccgga gtcaaggtct acctgaatcc
    10501 ctccgccgcc ggaaccgaac acgccgcgcg gacagtgcgg gaggcgttgc gtcgactcgg
    10561 atacggcgag gccttcgcga aactcccccc tgcggcggga tatccgttcg tcgcactgga
    10621 cctgggcacc tggaagacgc cacgcgtcaa ggtctacgtg agccacccgc gcatgtcggc
    10681 cgatgacgcc agcgcgctga gccgtagttc cggggccgcc gaggccgaca tcaggtactt
    10741 cttccacgcc accgcaggat cgttacttcc gactcagcgg ggcggcgacg acacgctgcg
    10801 gcttctcagg aggccggcgc tcacctgtca ttccttcacc caaggagacg ccgagccgag
    10861 cggcttcacg ctccacatcc ccgtacggga ctacgtccgc gacgacgagg aggccgtcac
    10921 ccgggcggcg gccctgctga cccggttcgg catggacccc tccatcctga accgcgggtt
    10981 gcgcgccctc acccgacgac aactcgccga cggtgccggg ctgatcgcct acctcgctct
    11041 cgtgtacgag cgaaatcagc ggccccggat caccgcctat ctgtcctccg aggcctacgc
    11101 cgtccggccg ccgcatgagc ggtacccgca ggacgaacgt gtaccagcag atctcagctc
    11161 gtcctgaacc cagggcacaa ggcctccggc cacgccagcc cgcacaccgc acagaaggaa
    11221 gccacgtgga gccgtaccgc atcaaagtcg tagaacccat cgcgttcacc accagagcgg
    11281 agcgcgaaga cgcgttgagg cgggtcgcct acaacccctt cgacctgcgt gccgacgaag
    11341 tcaccatcga cctgctgagt gactcgggga ccggcgccat ctccgcggaa cagctggccg
    11401 cgggcatgaa cggcgacgag tcgtacgccg gcagccgctc gttctaccgc tggcacgagg
    11461 tcgtctccga actcaccggc tatccccaca tcctgccggc acaccagggc cgggccgccg
    11521 agcgcatcct gttctcctca ctcctcaggc ccggcacgag tgtgctgtcc aacacccact
    11581 tcgacaccac gcgtgccaac gtcgagctga ccggctgtca ggcctatgac ctgccctgcg
    11641 ccgaggcgaa ggacctcgac agcgactatc ccttcaaagg caacatcgac ctgacagccc
    11701 ttgagcgtgc gttggagaac gcgcacgagg cccccgtggc agcggtgctg atgaccatca
    11761 ccaacaacgg tggcggtggc cagccggtca gcatggagaa cctgcaccgg accgccgcgc
    11821 tctgccgccg ccacgccgtg cccctgatcc tggacgcggc gcgcttcgcg gagaacgcct
    11881 ggctggtgac ccaacgcgaa ccgggctacg agggccgcac accccgccag gtcgccgagg
    11941 aggccttccg cctcgcggac ggctgcgtca tgagcgcgaa gaaggacggc atcgtacata
    12001 tcggcggctt catcggtctg aaggaccccg aactcgccga gcggtgccag ggcctgctca
    12061 tcgccaccga agggttcacc acctacggcg gcctggccgg ccgtgacctc gacatgatgg
    12121 cccgcgggct cctcgaagtc accgaaccgg catacctcgc ggaacgtgcc gacatagccg
    12181 gctacctcgc cgcacgtatc cgcgaagccg gagtcgacat cgtggaaccg gccggcctgc
    12241 acgccctcta tgtcaacgcc gggcggctcc tgccccacat cccaccgcac cagtaccccg
    12301 gcaccgcgct ggcctgtgag ctttacctcc gcggaggcat ccgctcggca gaactgggct
    12361 cgctgtatct gggtgaggag gacgagcaag gaaaccccac caggaccgcg ccctacgaac
    12421 tcgtgcggct ggcgctcccg cgccgcgtct acacccgcag ccattacgac catgtcgcca
    12481 acaccctggc ggacatagcc aagaaccccg aatcggtgca cggctaccgc atcgtgggcc
    12541 agtcgccgat actccgccac ttcagcatca aattggagtc tgtgcggtcc ggtaactgat
    12601 ccgccgtcgc ggccgggacg ccaaccggcc catcgcgccg cgcacggctc gtgccacgat
    12661 ccgtgcgccg cacacggctt gtgccacgct ccgcgggttg cccggcggag tacctgccgc
    12721 tgggctgaat caccagcgct tgggagcgtc gagcagcacg ccgtcgcatc cggcggcctc
    12781 gaagggaacc cgctcggcaa cgccgtccgc ttcccactgc gcgtaggagt cgtagacggt
    12841 gttgctggga gggaagtcgt gcggcgggta ctcccacgcg atccctgagc ggtcgccgta
    12901 gaggaaggcg ttcacgatgt cccgcagatc atggacgcct gccgcggcgc ccggcccggt
    12961 gcgggcagcc cgtggtggta tccgtcgtgg gcccggccct ggcccatgcc ccgtaaagtg
    13021 cctgctcacg cgtgggacga ccggctgtca ccttgccgtc gtcccggccg gcacatcggg
    13081 gtgatggtcc agaacctcct cacgacgacg gaccacggcc atgatcgcgc acgcccccgc
    13141 aaacggggta gaaggcgttt cgagcgttgc tccctttccc tcccgcccgc gcccggcgcc
    13201 ggtcacccgc acgccgatcc cactggttct gcgcgatcgg tggggcgagg cgggagcgag
    13261 ggagcaggcg gctgtcacag tccgggctgc tgtccggtcc tagtgactga ctgaacggtg
    13321 tgacccgtca cgccgtcgat gtcttcggtc gacgctcttc aagaggagaa cagcatgagc
    13381 cagatcaaca tcgcacgccc caacgcaccg acgtatgacg aattggtgcc gtcgcgctat
    13441 gcgctgaagg tcggcgacat cgacgtgatg gtgatcagcg acggggtact gccgataccc
    13501 gcagtgacga tggccaccaa cgcccccgcg gccgacctgg cggcctggct gaaagacatg
    13561 ttcctgccgc cggagacgct cgactggcca ctgaatgtgg ccgtggtgcg cagcggcggc
    13621 cggaccatcc tggtcgactc cgggctgggg acagagtttc ctggcttccc tcgggccggg
    13681 cagttggcca tgcggctgga cgccgccggg atcgatccgg catccgtgac cgacgtggtc
    13741 ctcacccatt tgcacatgga ccacatcggc gggctgctcg tcgacgggct gaggggccgg
    13801 ctgcgcccgg acctccgcgt tcacctggcg tccgctgagg cggagttctg ggaagcgccc
    13861 gacttctccc gcaccgccat gccgacaccg gtgccggacg tgctccgaac gaccgcctcg
    13921 cggttcctgg acgtgtaccg cagccagctg cggccgttcg agaaggagta cgaggtggct
    13981 ccgggagtgc tgatcagccg caccggtggt cacaccccgg gtcacagcat catccgtctg
    14041 gagtccggcg gcgaccgact gacgttcgcc ggtgatgccg tcttccagcc ggggttcgac
    14101 tgccccgact ggcacaacgg cttcgaccac gatcccgagg aatcggcccg cgtccggatc
    14161 cgtcttctga acgagctggc ggcgcgcggc gaacagctgg tcgccacgca tctgccgttc
    14221 ccgtccatct gccgtgtggc ggtcgccggg gatgccttcc gtttcgtacc ggccgtctgg
    14281 gactactgac cgtacttcga ccggaccggc gcgagaacag cgcgccggag gccaacctgg
    14341 tatgcggccc tggttgtcaa gtgaacaggg tggagcggtg cccactcgcc atcgccgtgg
    14401 gcgccgctcc ggcaacggtg agccggatct atctccgacc acaaccacgt ctcgtcctcc
    14461 ctccgagcgg gcccggtcgc ccttcgacca ggatgctcgc gcggtacccc gcaccggcca
    14521 cgacgggaac ggggccggcc gccgtcggcc agtgtctcgg tggcggtggc ggtggcggtg
    14581 catggtgccg cggccgggac ctggtggggg ccctcctgcc cgcagtgctg atgtttccag
    14641 gcaggtcggc ggggtggtgc cgacgcccgc cccgccggga cgctcctact tgctgagcca
    14701 gaggtcgggg ccgaagacct cgtaatgaat ggccgcgggg ctgagcccat gggtgagcag
    14761 gtcgccgcgg accgtccgca tgaacggcag cgggccgcag aggaacgcgg tggtgttctg
    14821 aggcagtgtc aggtcagaga tatccgcacg gccttcgcgc acccgcacca catgggtctc
    14881 ccgctcccgc tccagctcgc ccggttcccc ggcgacggtt ccgtaccgct ctcccacgcc
    14941 gttctcgtac cacaggtgta acgaggcacg ggtcagtcgg cccacgagct cggacagctc
    15001 caggcggtgg gcgtgatcgg tgggggagcg gtccgcatgg atgatgacca cgggccggtc
    15061 gggcgagacg ctggccaggt ggtcgagcat ggagagcatg ggggtgatgc cgatgcccgc
    15121 ggaagcgagg agcaatggtc cttcgccgtc gaggaggacc aggtcaccga agggcaggga
    15181 gaccttcaag gtccggcccg ctcgggcatg ggcgtgcagc caggaggaca cctccccctc
    15241 ggggacatgc ccgtcggccg agctctcccg cttgacggtg atgcgccagt tcttgtggcg
    15301 aggagacgtg gacaggctgt actggcgtat ctgccgtgcc ccgtcgggta gttcgacctg
    15361 gacgctgatg tactggccgg gcaggaaggg atcggtgggg agcccgtcgg ggcggcgcag
    15421 gacgaaggaa gcggtgtcgg gcgactcctc ggtgcgctct gcgacctcca tgtcccgcca
    15481 cacgacaccg ttctcgacgc cggcctcggc gtacagcctg gcctccatgg cgatgagggc
    15541 gttggccatc agccagtaca cctcgtccca ggcggcagcc acggccggag tgacagcgtc
    15601 gccgaggacc tccttgacgg cacccagcag gtgacggccc acgagggtgt actgctcgga
    15661 cgtgatcccc agtgaagcgt gtttgttggc gatgcggccg agcacggcgt caggacgctc
    15721 ttcggggtgt gtcacgagcg cggtggcgaa ggccgccact gctccggcga gggcctcgcg
    15781 ctgtgcgccg ttggcctggt tcgccctgtt gaacagggtg cgcagcaggt ccgggcgttc
    15841 ctcgaacatg cgagtgtaga agagctcggt gatggtgccg agggaggcac cgaccgtccg
    15901 aagtgtgtcg cggacgatcg gggctgatgg tgaggagagc aaggtgactc ctatcgcgat
    15961 catgcgacat gcctacgtct tgcgtacgac accatgttag tcagtgggag gccgcgctgt
    16021 gcgtgaaagg tgatgctttc agccgggtga ggagtggata tgaggtccgg tcacaccgtc
    16081 tgcaacgaca cggtgttgtt cggtacgacg cccgtgccga ccgggtagct cacctcttac
    16141 aagtgccccc tgcggtatcg caccgcaggg gggacccgcg tgtcttgggg gcgcttacac
    16201 ggcgcggtac agaccgcggc cggtccgccg gatgcgggag gagccgacca agcggtcgag
    16261 ggtgctccgc acggcgttga tgctgccgct gtcggtggct cggccgagcg ccgcggcgac
    16321 atcgcgggcg cgtacgtcga catcaccgac ctcggcgaag taatggagga tctgctcggt
    16381 gagcctgccg tagttcttcc gggcactctc cttgtcggag gactccggtg cggcgtcgtg
    16441 gtcctccggc cgggccgggg agtgttcttg gtgcgcgttc ccggcggagg aagtggcggt
    16501 gggcgcggcg gtggatgtgg cgtcgtgcgg ttccttcgcg ggccgcgccg gttccccgtg
    16561 tgctgcggcc tcggctgtcc gtgggggcgc gccaggggtg tctgtggtgt ggggaatacc
    16621 cggcccggcg ggcgacatga ggacctgaag ggcaccaaga gcccgctgga cggagctgag
    16681 atgggcgact accgcggcca gttccctctc cagggactgc ttctggactt ccaggcgggc
    16741 caagtcgtcc tggaggctct cggcggtgac ctcaatgtga tgtgccgcgt gggtgacaga
    16801 caccttgtgt tcctctcgtg ctcaaccctt gtgatcgtgt ccgcgctcga ctcgcctcgg
    16861 attgtcgtcc ggctccatac agataccact tcacatcata tggggggcgc cccaattgct
    16921 gtggtgtgat cggatcgccc ccacatggtg tcgggtcact gccggggtga cagcccgagc
    16981 ggcccggccg gggcggcgtg tgcggaagcg gctcggggct ccctgctcac gaccttcgtc
    17041 acgctgtacc gcccttcggc catgggcgga aatccggatt ccggacgacc ggttgaccga
    17101 caagtacccg ttttgtgtgc cacctgaggg cgctcagccc tccagggacg cagcgtagga
    17161 cgacaacttg gccggattca tgacccacat gatgcggtcg atgccctccg cggaaacgtc
    17221 cagcgacagc agggccacag ccttgcccgc ggtggagatg agcacggcag gccgtccatt
    17281 ggcctccgtc caccgcgact gcgcccgggg ccagaagcgc ggcgcgaacg cgacgaggta
    17341 ccgggagacg tgcgtacgcc cgacgacagg gatcttcgag gcgccgcgca ccccgccgcc
    17401 gtcggagtag ctgacgacgt ccgtggcgag gatctgctcc agctccgcca ggttcccgtg
    17461 gcgcgcggcg ttcaaaaaca cctcaagcag acgccggtgg tcggcgggac tgacacgctc
    17521 cttgcgctgg gcactgagat gcttgcgagc acggctcacc agttggcgtg tgttggcctc
    17581 cgtggtctcc aggatctccg cgatcctgcg atagggatac tcgaaggcct cgcgcaggac
    17641 ataggcggct cgttccaccg gattgagctt ctccagcaga aacaggacgg ccagatccag
    17701 ggcctcggcc cgctcggctc ccacctgcgg gtccgcggag gtgctgaccg gctcgggcag
    17761 ccacggaccc acgtacgact cgcgccgtac ccgggcggac tgggcgaagt tgatcgccag
    17821 acgcgtggtg atcgtcgtca ggaacgctga gggttcgagg atgtccgcgc ggtcggtctt
    17881 ctgccagcgc agccagacgt cctggacgat gtcctcggcc tccacggcgc tgccgagcac
    17941 gcggtagacg atgccgaaca gccgcggacg tacggcgagg aagtccttcg tcgcctggtc
    18001 gagagagtcg gtaccgtccc cagtgtgcat ggtcgcccct tccggatcga ggcccccatg
    18061 ctacaaaccg gcggagcaaa aggtgcggtc ggccaggtcg gtcctgacgt gtcgaacgga
    18121 cacactcgcg agcccccgta cgtgtcacag atccactcgg tctccgggca actcggccga
    18181 ggggcgggga gatgtgaccc gccccatcca catggcgact tacggaaggt tcacaacagt
    18241 gtcggacacg cacgcagggc acgcgcacgc agccggcgcc ccggcggctt cggatagctg
    18301 gctgaccgcg gcgcaggtgc tgcaggacgc cgcgcccctg acgatccccg agggcgcttc
    18361 tgcgatgacc atccaggtgg agtgggagcc gggagacccg ggcaccccgc cgcaccgcca
    18421 ctccggtccc gccttcggat atgtggtcga gggcgcggtc cgcttcgagt tggagggcga
    18481 acccgagcgg tggtcgaggc cggcggcacg ttctgggagc ctggcggcga cgtgatccac
    18541 tatcaggacg gcaacgccct cggtgacgcg cggacccggt tcgtggtgac catgatgtgc
    18601 gcacccggaa agccgatgct cgaactcgtc tccaaggacg agcttgcggg gcgcgcccgc
    18661 cttcgctccc cacgccccac cggatgagcc cgccggtacc gggccaccgc acgggagggc
    18721 atgcgacgcg acgaggtcct ccgacgccgt gcccgcgcca ccgcgcgccg atgacggcct
    18781 tgccgcgcat caggaagtcc gacggacaac tgtcgtgacg gacaactgtc gtggggtacc
    18841 cggagccatc cagcaggtcg gatgatcgcc gatgtgcggg ttggcgatgg cgggccccgc
    18901 cagcagcctg tcgagcggaa cctcgtcgcg tggcagcgcg gaaagtacca gcgaatcgcg
    18961 catcggggcg acgccgtccg agcggctccg gggacacatc ggtcacgagg ctcggggcga
    19021 gcgtgcggta cgggccgccc gagtgcccgc ccctcgccgc gggccggacg cggcgagggg
    19081 cgggccggta cggatggccg cgcgggcgga tcagccgaat tggccgggcc ggtagccacc
    19141 ggcgggagtc cggttgatga cgttgacgcg gttgtaggcg ttgatgacgg cgatgaggga
    19201 gatcagcgcg gccagctgct cctcgtcgaa gtgcttgacc gcgttcgccc aggcctcgtc
    19261 gccgaccccg cccgcggcgt ccgcggtgcg ggtaccctgc tccgccagtt ccagcgcggc
    19321 ccgttcggct tcggtgaaga ccgtggcctc tcgccaggtg gcgatcaggt ggagacgctg
    19381 agcggtctct cccgcgtggt cggcgtcctt ggtgtgcatg tcggtgcaga agccgcagcc
    19441 gttgatctgg ctcgctcgga tcttcaccag ctcctgtgtg gtgtgcggca gcgtcgagtc
    19501 cgacaccacc ttgttcgccg aattgaggtg cttcaggacc ttggccccga gcgtattgcc
    19561 gaagaagtcg agacgcgcgt ccatggtgtg ttctcctcgc cgtagtgctg attcacacta
    19621 ctgaccgggg tacccccgtg aactgtgaca ccgtgggacg tgtgtcctgc gtcacgctgg
    19681 ccaagtgtgc gcgacgcgcc gctctggagg ctcgcttccc cggtctgctg ccttcgtcgc
    19741 tgttgacgcc cgtcgcggag agtgcgggcg gtcatacgac tccgggcgcc gaggggccct
    19801 gacttggctc gactccgcac atcagcgagg cgcggcggcg cggcgggcaa cggcccggct
    19861 gcgacgttcc ccctccgcac gtcagcgagg ctcggtcgcg cgggcggcgc ggcagcggct
    19921 cggtgcgata ccccctccgc gcgtgcgtga ggctcgggcg gtacgggaaa acgtttgaac
    19981 acactgtgtc gcagcagggt tgctcacggt atggtcgtgg gcgcgcccct cacacgatgc
    20041 cgcgattccg tggtgttgga gccggagcgg cccaggcggt gagcgggggg agcgtccccg
    20101 cccggccaac gccgctccgc tcggccgact cgcgccccgg aagccgccag cccggctgcc
    20161 ctcgacgtga cctctaccga cgaaggaccc cgactcatgc ctgcgatcct tatccacggt
    20221 gtccccgaca cccaccaagt gtgggacggc gtgcgccggg agctgacccg gaccgacgtg
    20281 gaagcctgga acctgccggg gttcggcgcg ccacggccgg agggcttcac atcggccaag
    20341 aaggagtacg tggactggct catcgaccgg ctggaacgcg tcggtgagcc ggtcgacctg
    20401 gtcggccacg actggggctg tatcctcacg gcgcgggtcg cctccctacg gcccgacctg
    20461 gtccgcacct gggccggtgg caacgggccg gtgaacgccg aatatgtatg gcatccgctc
    20521 gcgaagacct ggcagcaccc cgtcgagggc gcccgcttca tgagtgaact ggaacccgac
    20581 tcgttcgccc acgatgtggc ggccggcttc gacgtccccg tcgatctcgc cagggagatg
    20641 gccggccggg tgggcgaggc catgaaggac agcgtcctgg ggctctaccg ctccgctgtg
    20701 accatgggcg aggagtggga accggggctg gcacgggtga ccgcgccgtg cctcgtgttc
    20761 tggggagtcc ttgatcccgc ctgcccgatc gggttcggtg agaagctcgc ggtctccctg
    20821 cgagccccgg aagtcgtgag actggactgc aatcactggc cgctgctgca aaagcccggt
    20881 gaggtcgccg cggccatcga ggcacactgg aagtcgccga ccgatcaggt cagttgagcg
    20941 gcgagtcccc cggcccggca tccgacggtc aagtcccctg acacgcgatc gctggcgagc
    21001 cagatcgagg agagttgcct gcggcgcgtc ggggcgttgc cggccacggc gcaacggttg
    21061 cttctggcgg cggtcgccga gcgggtgggg acgcgcggtc gctcacacct acgcggacat
    21121 cgtcgacatg ctgcacctca gcgtcgtcaa cgtccgcgag gtcgcga
//
