LOCUS       NZ_CP045178            26704 bp    DNA     linear   CON 25-NOV-2024
DEFINITION  Streptomyces tsukubensis strain AT3 chromosome, complete genome.
ACCESSION   NZ_CP045178
VERSION     NZ_CP045178.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces tsukubensis
  ORGANISM  Streptomyces tsukubensis
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 8615214)
  AUTHORS   Cao,G., Zhong,C., Fu,J., Zhang,P., Liu,M. and Zong,G.
  TITLE     Complete genome sequence of Streptomyces tsukubaensis AT3
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8615214)
  AUTHORS   Cao,G., Zhong,C., Fu,J., Zhang,P., Liu,M. and Zong,G.
  TITLE     Direct Submission
  JOURNAL   Submitted (14-OCT-2019) Shandong Medicinal Biotechnology Center,
            Shandong First Medical University, 18877 Jinshi Road, Jinan 250062,
            China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 01-OCT-2019
            Assembly Method :: SOAPdenovo v. OCT-2019; SPAdes v. OCT-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 997.0x
            Sequencing Technology             :: Illumina HiSeq; PacBio RSII
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009296025.1-RS_2024_11_20
            Annotation Date                   :: 11/20/2024 08:40:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,005
            CDSs (total)                      :: 6,919
            Genes (coding)                    :: 6,691
            CDSs (with protein)               :: 6,691
            Genes (RNA)                       :: 86
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 65
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 228
            CDSs (without protein)            :: 228
            Pseudo Genes (ambiguous residues) :: 0 of 228
            Pseudo Genes (frameshifted)       :: 76 of 228
            Pseudo Genes (incomplete)         :: 184 of 228
            Pseudo Genes (internal stop)      :: 10 of 228
            Pseudo Genes (multiple problems)  :: 38 of 228
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 05:10:03
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7324704
            Orig. end                         :: 7351408
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045178.1.
            Bacteria and source DNA available from Dr. Guangxiang Cao.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26704
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="29"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26704
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26704
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16704](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16704
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(90..1022)
                     /locus_tag="GBW32_RS30830"
                     /old_locus_tag="GBW32_30820"
     CDS             complement(90..1022)
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006383714.1"
                     /locus_tag="GBW32_RS30830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30820"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_077965761.1"
                     /transl_table=11
                     /translation="MGAGHDHGHGGSTSSTVTSAYRGRLRVALGITLAVMVVEIVGGLL
                     ADSLALIADAAHMATDALGLGMALLAIHFAARPASDRATFGYARAEILAALANCLLLLG
                     VGGYVVFEAVERFITPADTHGGQTIVFGVIGLVANMISLTLLVRGQQESLNVRGAFLEV
                     AADALGSLAVIVSAVLILATGWRAADPIASLIIGLMIVPRTWKLLRETVHVLLEAAPKG
                     VDMAEVRAHIVALPGVEDVHDLHAWTITSGMPVLSAHVVVGADTLNAIGHEKMLHELQG
                     CLGHHFDVEHCTFQLEPSGHAEHEAKLCL"
     misc_feature    1020..1035
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.87"
                     /tool="antismash"
     misc_feature    1071..1087
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.79"
                     /tool="antismash"
     gene            complement(1166..2173)
                     /gene="galE"
                     /locus_tag="GBW32_RS30835"
                     /old_locus_tag="GBW32_30825"
     CDS             complement(1166..2173)
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (64-183). E-value:
                     2.2e-09. Score: 28.7. Matches aSDomain:
                     nrpspksdomains_GBW32_RS30835_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534459.1"
                     /locus_tag="GBW32_RS30835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30825"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_077965762.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1e-15, bitscore:
                     56.2, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 5.4e-10,
                     bitscore: 37.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVTRALAAAGERVVVLDDVSSGIPERLPADI
                     PLVRGSILDGEPLRRVFAEHEVTGVVHLAGRKQVGESVERPLHYYRENLHGLTVLLDAV
                     AEAGIQRFVFSSSAAVYGNPPTADLVTEDTPCAPLSPYGETKLAGEWLVRATGRAHGIA
                     TVCLRYFNVAGAGAPELADTGVFNIVPMVFDRLTRDEAPRIFGDDYPTADGTCVRDYIH
                     VSDLARAHLAACRRTGEGAGAGDLTVNVGSGTGVSVRELVTLIGEVTGDRRPALVEPRR
                     PGDAPVAVASARLAGEALGWKAVLGVREMVESAWEGWLLRHPEARSCEGRATED"
     aSDomain        complement(1625..1981)
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GBW32_RS30835_NAD_binding_4.1"
                     /evalue="2.20E-09"
                     /label="GBW32_RS30835_NAD_binding_4.1"
                     /locus_tag="GBW32_RS30835"
                     /protein_end="183"
                     /protein_start="64"
                     /score="28.7"
                     /tool="antismash"
                     /translation="HEVTGVVHLAGRKQVGESVERPLHYYRENLHGLTVLLDAVAEAGI
                     QRFVFSSSAAVYGNPPTADLVTEDTPCAPLSPYGETKLAGEWLVRATGRAHGIATVCLR
                     YFNVAGAGAPELADT"
     CDS_motif       complement(2084..2170)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_GBW32_RS30835_0001"
                     /evalue="5.50E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="GBW32_RS30835"
                     /protein_end="30"
                     /protein_start="1"
                     /score="19.0"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVTRALAAAGERVVVL"
     misc_feature    complement(2262..2276)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     gene            2454..4283
                     /locus_tag="GBW32_RS30840"
                     /old_locus_tag="GBW32_30830"
     CDS             2454..4283
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014676195.1"
                     /locus_tag="GBW32_RS30840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30830"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_077965764.1"
                     /transl_table=11
                     /translation="MSTAILIGQPVPGSPLEGDLRALGFDVRTVSDAAQAEVEIAAVPA
                     SARVAVVDARFVGHQHTLRLGLTDPRFPLACVPGAVTAKPEARHELTQALTSQTHAPVG
                     GQSPLERWDGTGGPLPDRLADAVESAGTAVHRPELGTLVAAVPEDPQSRNEARQRVAAV
                     DDEAVRLRSAVKARDGFFTTYCISPYSRYIARWCARRGLTPNQVTTASLLVALIAAGCA
                     ATGTRGGFVAAGVLLIASFVLDCTDGQLARYSLQYSTLGAWLDATFDRAKEYAYYAGLA
                     LGAARGGDDVWALALGAMVLQACRHIVDFSFNEANHDAQANTSPTAALSDKLDSVGWTV
                     WLRRMIVLPIGERWALIAVLTAVTTPRVTFYVLLIGCALAACYTTAGRVLRSLTRRARR
                     TDRAARALADLADSGPLAGGLGAALRGVGRKLPGFGAPFLALLGGAVVTALAAFTDFGG
                     VWPVVGALVYTLTSALAVARPLKGPLDWLVPPFFRAAEYGTILLLAARADVNGALPAAF
                     GLVSAVAYHHYDTVYRIRGGTGAPPNWLVRSVGGHDGRTLVVTIAAVALSASAFTVALT
                     VIAVLVALLVLFESIRFWVSSHAPAVHDEGEPA"
     gene            4280..5032
                     /locus_tag="GBW32_RS30845"
                     /old_locus_tag="GBW32_30835"
     CDS             4280..5032
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983099.1"
                     /locus_tag="GBW32_RS30845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30835"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_077965767.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.9e-09, bitscore:
                     35.1, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVGPEGKEDSITVLDLTLG
                     NFAEIGLTEVAIIVGYRKEAVYERKAALEQKYGLKLTLIDNDKAEEWNNAYSLWCGRDS
                     IRHTVILANGDTVHPVSVERTLLAARGDGKKIILALDTVKNLADEEMKVVADPEKGVSK
                     ITKLMDPAEATGEYIGVTLIEGEAADELADALKATYERDPQLYYEDGYQELVNRGFKVD
                     VAPIGEVTWVEIDNHDDLAKGREIACQY"
     gene            5020..6081
                     /locus_tag="GBW32_RS30850"
                     /old_locus_tag="GBW32_30840"
     CDS             5020..6081
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007494151.1"
                     /locus_tag="GBW32_RS30850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30840"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_077965769.1"
                     /sec_met_domain="Fe-ADH (E-value: 5.4e-21, bitscore: 73.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 5.7e-08, bitscore:
                     30.9, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGALDDLAAVLCDQRISPSGKLAVAISG
                     GSGARLRERLAPALPGATWYEVGGGTLDDAIKLADAMKSGHYDAVVGLGGGKIIDCAKY
                     ASARIGLPLVAVATNLAHDGLCSPVATLDNDAGRGSYGVPNPIAVVIDLDVIREAPERY
                     VRSGIGDVISNISAVADWELSHAETGEQIDGLAAAMARQAGEAVLRHPGDVSDDGFLQV
                     LAEGLVMTGISMSVAGDSRPSSGACHEINHAFDILYPKRAASHGEQVGVGTVFAMHLRG
                     AQGAAAHMAEVLRRHRLPVLPQDIGFSVDEFVRAVEFAPQTRPGRYTILEHLHLTTDQI
                     KDAYADHAKAIGS"
     gene            6059..6838
                     /locus_tag="GBW32_RS30855"
                     /old_locus_tag="GBW32_30845"
     CDS             6059..6838
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008413838.1"
                     /locus_tag="GBW32_RS30855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30845"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_077965770.1"
                     /transl_table=11
                     /translation="MPRPSVAELRPVVHPAGVKDRRSGEHWGGRLYMREISLHIDPYLV
                     NTRITPNQLTYLMTVFGVLACPALLWPGIPGAVLGAVMVQLYLLLDCVDGEIARWRKQF
                     SLGGVYLDRVGAYLTDAAVLVGFGLRGADLWGSGRIDWLWAFLGTLAALGAIMIKAETD
                     LVGVARHQTGLPPVKESASEQRSSGMALARKAAGALKFHRLILGIEASLLIIVLAVVDQ
                     IRGDLFFTRLGIAVLAGIAVVQTLLHLVSILASSRLK"
     gene            6847..7731
                     /locus_tag="GBW32_RS30860"
                     /old_locus_tag="GBW32_30850"
     CDS             6847..7731
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010983096.1"
                     /locus_tag="GBW32_RS30860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30850"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_077965772.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2.7e-09,
                     bitscore: 35.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDPLKVGAVIITMGTRPDELRALLDSLAKQEGGPVEAVVVGNGS
                     PVPDLPEGVRTVELPENLGIPGGRNVGIEAFGPAGREMDVLLFLDDDGLLAGTDTARLC
                     REAFEADPELGIISFRIADPETGQTARRHVPRLRASDPMHSSRVTTFLGGANAVRTRVF
                     ADAGVLPGDFFYAHEETDLAWRALDAGWMIDYRADMVLLHPTTAPSRHAVYHRMVARNR
                     VWLARRNLPAPLVPVYLGVWLLLTLARRPSAPALKAWFGGFKEGWSSPCGPRRPMKWRT
                     VWRLTRLGRPPVI"
     gene            7831..8766
                     /locus_tag="GBW32_RS30865"
                     /old_locus_tag="GBW32_30855"
     CDS             7831..8766
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="GBW32_RS30865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30855"
                     /product="ABC transporter permease"
                     /protein_id="WP_077965782.1"
                     /transl_table=11
                     /translation="MSDTTQDGGVALTTPPSPDAGLSRPELAAKYGLTVSGARPGLFEY
                     VRQLWGRRHFILSFSQAKLTAQYSQAKLGQLWQVATPLLNALVYFFIFGLLLGGRKGIP
                     HNAYVPFLVTGVFVFTFTQSSVQAGVKAISGNLGLVRALHFPRASLPISFSLQQLQQLL
                     FSLIVLVIVMVGFGYYPDLSWLLVIPALALQLVFNTGLALVFARMGAKTPDLAQLMPFI
                     MRTWMYASGVMFSIPAMLATKDVPSWVSDVLQWNPASIYMDLIRFAMIDDYGPKYLPPH
                     VWAFAAAWAVVIGIGGFVYFWKAEERYGRG"
     gene            8753..9547
                     /locus_tag="GBW32_RS30870"
                     /old_locus_tag="GBW32_30860"
     CDS             8753..9547
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010266784.1"
                     /locus_tag="GBW32_RS30870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30860"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_179120069.1"
                     /transl_table=11
                     /translation="MAVAEDKNDGRAHIPTVIADELHIVYRVNGGGRAKGGATAALSRI
                     VRRGGESPGVRKVHAVRGVSFTSYRGEAIGLIGSNGSGKSTLLRAIAGLLPAEKGRVYT
                     DGQPSLLGVNAALMNDLTGERNVVLGGLAMGMTREQVKERYQSIVDFSGINEKGDFITL
                     PMRTYSSGMAARLRFSIAAAKDHDVLMIDEALATGDRKFQKRSEARIRELRKEAGTVFL
                     VSHNNKSIRDTCDRVLWLERGELRMDGPTDEVIKEYEKFTSK"
     gene            10001..10909
                     /gene="hpnC"
                     /locus_tag="GBW32_RS30875"
                     /old_locus_tag="GBW32_30865"
     CDS             10001..10909
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049655.1"
                     /locus_tag="GBW32_RS30875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30865"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_077965783.1"
                     /sec_met_domain="PT_phytoene_like (E-value: 5.1e-40,
                     bitscore: 136.2, seeds: 61, tool: rule-based-clusters)"
                     /sec_met_domain="phytoene_synt (E-value: 1.1e-37, bitscore:
                     128.4, seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRADRGTNPGAPARDTLGKAADENFPVAPFFLPRAWRDDLMAVYG
                     FARLVDDIGDGDLAPGGADARHLGVGPLEADDRLVMLDAFETDLHRVFDASATPHHPLL
                     RALRPTVRRCGLIPDPFLALIEANRQDQRVSRYATYEELRAYCELSANPVGRLVLGITG
                     TESAERIRRSDAICTALQIIEHLQDVSEDLRRDRVYLPAEDMTRFHVTEADLAAPTGGA
                     SVRALVAFEVERAHELLNEGMPLVGSVHGRLKLLLAGFVAGGRAALVAVRDAGHDVLPR
                     PPKPTKLRLLREVGATLRGEG"
     gene            10918..11856
                     /gene="hpnD"
                     /locus_tag="GBW32_RS30880"
                     /old_locus_tag="GBW32_30870"
     CDS             10918..11856
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552437.1"
                     /locus_tag="GBW32_RS30880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30870"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_077965784.1"
                     /sec_met_domain="phytoene_synt (E-value: 8.5e-53, bitscore:
                     178.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 4.6e-67,
                     bitscore: 225.0, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEETQGLSAPVLAAYSYCETVTGQQARNFAYGIRLLPPPKRRAMS
                     ALYAFSRRVDDIGDGTLEPEIKAARLDETRTLLGRVKNGSVQEDDTDPVAVALTHAATH
                     FPLDLGGLDELIDGVVKDVRGETYETWDDLKVYCRCVAGAIGRLALGVFGTEPGVRDTE
                     RAAEYADTLGLALQLTNILRDIREDALDGRTYLPADDLGKFGCSAGFAGTVPPPGSDFA
                     GLVHFEARRARELFAEGYRLLPMLDRRSGACVAAMAGIYRRLLERIAREPEAVLRGRVS
                     LPGHEKAYVAVRGLSGLDARNVSRKTLGGRA"
     gene            12026..13417
                     /gene="hpnE"
                     /locus_tag="GBW32_RS30885"
                     /old_locus_tag="GBW32_30875"
     CDS             12026..13417
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018100145.1"
                     /locus_tag="GBW32_RS30885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30875"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_077965785.1"
                     /sec_met_domain="DAO (E-value: 3.8e-07, bitscore: 28.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSGQRTRPRDPADDHAVVVGGGLAGVTAALGLADSGMRVTLIEGR
                     PRLGGLAFSFRRGDLTVDNGQHVYLRCCTAYQDFLRRIDGLALAPVQERLDVPVLDAGT
                     NRLGRLRRNALPVPLHLAAGLARYPHLSLAERAAVGRAALALKKLDPADPALDEQDFGS
                     WLARHGQSPRAVEALWDLVGVATLNARAGDASLALAAKVFRTGLLSEPGAADIGWAHVP
                     LGELHDTLARRALDKAGVRTELRTRANTVSRTEEGGWRVVTDKETLDAGTVVLAVPQRE
                     THALLPDGALDEPGLLLELGTAPILNVHVVYDRKVLRRPFFAGLGTPVQWVFDRTAASG
                     LEQGQYLALSQSTAHDEIDAPVSALRERYLPELERLLPAARGAQVKDFFVTRERTATFD
                     PAPGTGRLRPGTRTRAPGLYLAGAWTATGWPATMEGAVRSGAGAAAAALRTLGRAHDHL
                     FEEAA"
     gene            13414..14562
                     /locus_tag="GBW32_RS30890"
                     /old_locus_tag="GBW32_30880"
     CDS             13414..14562
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016639270.1"
                     /locus_tag="GBW32_RS30890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30880"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_077965786.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.1e-59, bitscore:
                     200.6, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLDLLGPGPQNPSSTGTSSTGTRGETVPTVPSADSAADAADVTA
                     LLERGRTLATPVLRSAVDRLAPPMDTVAAYHFGWIDADGRPAEGDGGKAVRPALALISA
                     EAAGAPPETGVPGAVAVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDAL
                     FALANEVLLELGTPEAGRATRRLTTATRALIDGQAQDISYEHRERVSVEECLEMEGNKT
                     GALLACAVSVGAVLGGADDHTADTLEKYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSD
                     LRQRKKSLPVVAALAAGGAASDKLAGLLAADAGTDDPAAFSEEEFAARAALIEEAGGRE
                     WTAQEARRQHTVAIEALDAITLPDHVRAQLVALADFVVVRKR"
     gene            14725..16704
                     /gene="shc"
                     /locus_tag="GBW32_RS30895"
                     /old_locus_tag="GBW32_30885"
     CDS             14725..16704
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008744685.1"
                     /locus_tag="GBW32_RS30895"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30885"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_077965787.1"
                     /sec_met_domain="T2TS (E-value: 9.6e-144, bitscore: 478.5,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSAGAVSPEAASASAPPDPSPGVAGPRETAERATRRAVE
                     FLLSNQDEQGWWKGDLATNVTMDAEDLLLRQFLGISDEKTTRAAALFIRGEQREDGTWA
                     TFYKGPGELSTTIEAYVALRLAGDSPEAPHMAKASAWVRERGGVASARVFTRIWLALFG
                     WWKWDDLPELPPELMFFPKWMPLNIYDFGCWARQTIVPLTVVSAIRPVRPAPFALEELH
                     TDAAVPNPAVPFAPVASWDGAFQRLDRVMHGYRKFVPRRLRRTAMNAAARWIIERQEND
                     GCWGGIQPPAVYSVMALHLLGYDLDHPVLRTGLESLDRFAVWREDGARMIEACQSPVWD
                     TCLATIALADAGVAPDHPQLVRAADWMISEQITRPGDWSVRRPGLVSGGWAFEFDNDNY
                     PDIDDTAEVILALRRVAHPDKAAVEAAVRRAAEWSAGMQSRNGGWGAFDADNTSPFPNR
                     LPFSDFGEVIDPPSADVTAHMVEMLALEGLAHHPRTRRGVEWLLAEQEANGSWFGRWGV
                     NYVYGTGAVVPALTAAGLPLSHPAIRRGVEWLESVQNDDGGWGEDLRSYDDPSWAGRGA
                     STASQTGWALLALLAAGERESKAVERAVTYLAETQAANGTWDEPYFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVHGAAPEDS"
     gene            16704..17366
                     /locus_tag="GBW32_RS30900"
                     /old_locus_tag="GBW32_30890"
     CDS             16704..17366
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848330.1"
                     /locus_tag="GBW32_RS30900"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30890"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_077965788.1"
                     /transl_table=11
                     /translation="MSKFSGADGGARNPSPLLIACALGIEQLALRSGDRKSARGPVTVL
                     RTGMGPRAAERAITRALGDGRGANTAVVATGFCAGLEPGMHPGDLVVAEETRDARGTTP
                     CAGTALLADAVARAVPGRAVHTGPLAGSDHVVRGQERAELGATGAVAVDMESAATLRSA
                     LAVGPRPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPAFYEWHRSLLLPRR"
     gene            17372..18394
                     /gene="hpnH"
                     /locus_tag="GBW32_RS30905"
                     /old_locus_tag="GBW32_30895"
     CDS             17372..18394
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015037634.1"
                     /locus_tag="GBW32_RS30905"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30895"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_077965789.1"
                     /sec_met_domain="PF04055 (E-value: 5.3e-17, bitscore: 61.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.2e-09, bitscore: 34.3,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQTIRVGTYLMEQKLRKRTKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKRKYVF
                     LCTNAMLMRKKMEKFTPSPYFAFAVHIDGLKERHDESVAKEGVFDEAVAAIKEAKRRGF
                     RVTTNSTFFNTDTPQTIIEVLDFLNDDLQVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKAFAGGNRGRWRLNHSPLFLDFLEGKTDYDCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRQLIEETDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESIRAARETVSGNRG
                     "
     misc_feature    complement(17418..17432)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.62"
                     /tool="antismash"
     gene            18565..20487
                     /gene="dxs"
                     /locus_tag="GBW32_RS30910"
                     /old_locus_tag="GBW32_30900"
     CDS             18565..20487
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386171.1"
                     /locus_tag="GBW32_RS30910"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30900"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_077965790.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 3.3e-109,
                     bitscore: 363.0, seeds: 174, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTLLETIRGPRDLKALGQEEVRELAAEIREFLIQAVSKTGGHLGP
                     NLGVVELTLALHRVFESPRDRILWDTGHQSYVHKLLTGRQDFSKLRKKGGLSGYPSRAE
                     SEHDVIENSHASTVLGWADGLAKARDVQGMQGHVVAVTGDGALTGGMAWEALNNIAAAK
                     DQPLIIVVNDNERSYAPTIGGLADHLATLRVTNGYEKVLAWGKDVLDRTPVVGRPLYES
                     LHGAKKGFKDAFAPQGMFEDLGLKYLGPFDGHDMEAVESGLRRAARFEGPVIVHCITEK
                     GRGYEPALRHDADRFHTVLAMDPLTCEPLTPSGPPSWTSVFSDELVRIAEERDDIVALT
                     AAMLDPVGLTPFAERFPDRIWDVGIAEQHATVTAAGLATGGLHPVVALYATFLNRAFDQ
                     LLMDVALHKCGVTFVLDRAGVTGADGASHNGMWDMSVLQVVPGLRIAAPRDAGQLRAQL
                     REAVDVHDAPTLVRYPKESVGEDIPAVGTVGSMDVLHRAESAEVLLVAVGVMAPVCLQA
                     ARLLQDRGIGATVVDPRWVKPVDPELPALAAAHRLVAVVEDNSRASGVGAAVALALGDA
                     EVDVPVRLFGIPDQFLAHGKRGELLADLGLTPVEIAGRIGATLDRKGAGAETGATLDRK
                     ENEEA"
     gene            20484..21911
                     /locus_tag="GBW32_RS30915"
                     /old_locus_tag="GBW32_30905"
     CDS             20484..21911
                     /NRPS_PKS="Domain: Aminotran_3 (56-378). E-value: 1.5e-89.
                     Score: 292.3. Matches aSDomain:
                     nrpspksdomains_GBW32_RS30915_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378204.1"
                     /locus_tag="GBW32_RS30915"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30905"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_077965791.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.4e-87, bitscore:
                     292.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTIGTSGTTGEESGAATKGFDLATLLAERGGERYDLHTRYLNHQL
                     PRMLHTIGFDKVYQRAEGAYFWDEDGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDAS
                     LADLTRFDCQPLPGLLAEKLLAHSPHLDRVFFGNSGTEAVETALKFARFATGRKRVLYC
                     THAFHGLTTGSLSVNGEKGFREGFAPLLPDTPIPLGDLDALEKELKRGDVAGLIVEPIQ
                     GKGVHTTPPGYLRAAQELLRKHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVCVAK
                     SLSGGYVPVSATLGKDWIFKKVYSSMDRVLVHSASFGANAQAMAAGLAVLGAMEDENIV
                     ANARSSGELLRNRLAELIPRYELLADVRGRGLMIGIEFGRPDSLKLRSRWTVLQAARKG
                     LFAQMVVVPLLQKHRILTQVSGDHLEVIKLIPPLVIGEREVDRFVAAFTAVMDDAHNGG
                     LMWDFGKNLMKQAVANR"
     aSDomain        20652..21617
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_GBW32_RS30915_Aminotran_3.1"
                     /evalue="1.50E-89"
                     /label="GBW32_RS30915_Aminotran_3.1"
                     /locus_tag="GBW32_RS30915"
                     /protein_end="378"
                     /protein_start="56"
                     /score="292.3"
                     /tool="antismash"
                     /translation="VYQRAEGAYFWDEDGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAEKLLAHSPHLDRVFFGNSGTEAVETALKFARFATGRKRV
                     LYCTHAFHGLTTGSLSVNGEKGFREGFAPLLPDTPIPLGDLDALEKELKRGDVAGLIVE
                     PIQGKGVHTTPPGYLRAAQELLRKHKALLIADEVQTGLGRTGDFYAYQHEEGVEPDLVC
                     VAKSLSGGYVPVSATLGKDWIFKKVYSSMDRVLVHSASFGANAQAMAAGLAVLGAMEDE
                     NIVANARSSGELLRNRLAELIPRYELLADVRGRGLMIGIEF"
     misc_feature    22030..22044
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.51"
                     /tool="antismash"
     gene            22261..22839
                     /locus_tag="GBW32_RS30920"
                     /old_locus_tag="GBW32_30910"
     CDS             22261..22839
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012999178.1"
                     /locus_tag="GBW32_RS30920"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30910"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_077965958.1"
                     /transl_table=11
                     /translation="MPAVAPKLRELRRTAGLTLEAAARAASLSPAHLSRLETGRRQPSL
                     PMLLALSRTYGTTVSELLGESTADRDAVVRGGDTEPTRAGGWTYWQAGGQGRGMQTLRV
                     HVPHGAQGDMVRVHPGEEWLYVLGGRLRLRLGDSTHVLKPGDSAHFDSLTPHRIAAADQ
                     GGADLLFVHTLMQSPVTALCLGDGNPGGA"
     gene            22839..23168
                     /locus_tag="GBW32_RS37875"
     CDS             22839..23168
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040000.4"
                     /locus_tag="GBW32_RS37875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_077965792.1"
                     /transl_table=11
                     /translation="MSDASTNDERTASTNDERTATAGGTPAAGATPLTDATPGQGADAS
                     TGQGDPVAPMREEPAPMRVEPVKSRSIEDKLPRGLWVRLFAYIIAGHLVAAFLYLLFTL
                     GEHSQ"
     gene            complement(23223..24026)
                     /locus_tag="GBW32_RS30930"
                     /old_locus_tag="GBW32_30920"
     CDS             complement(23223..24026)
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018848325.1"
                     /locus_tag="GBW32_RS30930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30920"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_179120070.1"
                     /transl_table=11
                     /translation="MTQQVPPQAEPELEAVRNFRDVGGIPTVDGGRVRAGRLFRSGHLA
                     HATASDTAFLSSLGLHTVFDFRNAADQALEGKDVDLPGVRNVSMPLNDPADGAGFWKLV
                     RNGDIGQLHALLGDGRAATRMTDTYRSVITEKTAQHGELLRALAGDSVPALLHCAAGKD
                     RAGMSIAIVLLAVGAEPGAIEEDYLKSNAPHRRYKVRRDSDAPGGMSPEVMELLNPLFE
                     ARAEYLHAALETIEETWGSTDRYFEEGLGLTPELRGTLRGQLVES"
     misc_feature    24148..24161
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.91"
                     /tool="antismash"
     misc_feature    complement(24326..24340)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.71"
                     /tool="antismash"
     regulatory      24356..24514
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            24519..25277
                     /locus_tag="GBW32_RS30935"
                     /old_locus_tag="GBW32_30925"
     CDS             24519..25277
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009069991.1"
                     /locus_tag="GBW32_RS30935"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30925"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_077965796.1"
                     /transl_table=11
                     /translation="MPATGKHRRSSRRLSRGLAVATTGGAVVALPLLGAAGAHAATPAA
                     APQKAETTYSVAAGDTLAKIARDHHVSGGWQKLYEANHKAVGSDPAKIKPGMELNLVVA
                     SAAKAPATGSTQSGSGWQAPVKASIGTGYQASGGSWSSGHHTGIDFLVGSGTSVKAAAA
                     GTVVAAGDGGAYGNQVVVHHADGHYTQYGHLSSISVSVGQQVSEGQQIALSGATGNVTG
                     PHLHFEVRTGPDYGSDINPLDFLHQHGVSA"
     misc_feature    complement(25443..25457)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.39"
                     /tool="antismash"
     gene            25535..26326
                     /locus_tag="GBW32_RS30940"
                     /old_locus_tag="GBW32_30930"
     CDS             25535..26326
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005308864.1"
                     /locus_tag="GBW32_RS30940"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="GBW32_30930"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_107502691.1"
                     /transl_table=11
                     /translation="MAQVSRFPSNPVIRSYAAVGDSFTEGVGDPGPGGGYVGWADRLAV
                     LLADRLPEHTFRYANLAVRGKLLDQIVAGQVARAKELAPDLVTFAAGGNDMLRPGADPD
                     DAAERFERAVADLRDSVGTVMVTTGFDTRDTPVLRRLRGKIATYNEHVRAVADRYGCPV
                     LDLWSLKTIQDRRAWDTDRLHLSAEGHTRVALRAGLVLGLEVPADPDQPWPPLPPRGTL
                     EERRDDITWAREYLVPWIGRRLRGESSGDHVVAKRPDLLPL"
ORIGIN
        1 gcgtgcgtcg gcggcgcgcg ctcggggccc cgaccggcca ccgcggacgg ccgtactccc
       61 ggtcggccac ggcgtggccc gccacggctt cagaggcaca gcttggcctc gtgctcggcg
      121 tggccgctcg gctccagctg gaaggtgcag tgctcgacat cgaaatgatg accgagacat
      181 ccctggagct cgtggagcat cttctcgtgg ccgatggcgt tcagcgtgtc ggcgccgacc
      241 acgacgtgcg cggagaggac gggcatgccg gaggtgatgg tccaggcgtg caggtcgtgt
      301 acgtcctcga cgccgggcag cgccacgatg tgggcccgca cctcggccat gtcgaccccc
      361 ttgggggccg cttcgaggag gacgtgcacc gtctcccgca gcagcttcca ggtacgcggc
      421 acgatcatca gaccgatgat cagcgaagcg atggggtccg cggcccgcca ccccgtggcg
      481 aggatgagca cggcggagac gatcaccgcg agggagccga gcgcgtcggc cgccacttcg
      541 aggaaggcgc cgcgcacgtt caggctctcc tgctgccccc gcacgagcag cgtcagggag
      601 atcatgttgg cgaccaggcc gatcacaccg aagacgatcg tctgtccgcc gtgcgtgtcg
      661 gccggggtga tgaaccgctc gacggcctcg aacacgacat agccgcccac gccgagcagc
      721 agcagacagt tggcgagcgc cgcgaggatc tccgcccgcg cgtagccgaa ggtggcccgg
      781 tcgcttgcgg gcctcgcggc gaagtggatg gcgagcagcg ccataccgag accgagggcg
      841 tcggtggcca tgtgcgccgc gtccgcgatc agggcgagcg agtcggcgag gagccccccg
      901 acgatctcca cgaccatgac ggcgagcgtg atcccgaggg cgacccgcag ccgcccccgg
      961 taggcggagg tcaccgtgga ggacgtggac ccgccgtgtc cgtgatcgtg ccctgccccc
     1021 atggaaacca tcctccgcct ctgtgccggt gtcctggaag ccccagtgaa ctaccggcag
     1081 ggggtatggg gcaacacggg gctgaacacc gttgtcgttc cccctgacct gcggtgatgt
     1141 ccgcaggtca gggatcggtc gacggtcagt cctcggtggc gcgcccctcg caggagcggg
     1201 cctctgggtg gcgcagcagc cagccctccc acgccgactc gaccatctcg cgcacgccga
     1261 ggaccgcctt ccagccgagc gcctcacccg cgagccgcgc ggaggccacg gcgaccggcg
     1321 cgtcccccgg acggcggggt tcgaccaggg ccggacggcg gtcacccgtg acctcaccga
     1381 tcagcgtgac caactcgcgc acggacaccc ccgtgccgct gccgacgttg accgtcagat
     1441 cgcccgcgcc ggccccctca ccggtcctgc ggcacgccgc caggtgcgcc cgagcgagat
     1501 ccgagacatg gatgtagtcg cgcacacagg tgccgtcggc ggtcgggtag tcgtcgccga
     1561 agatccgtgg tgcctcgtcc ctggtgagcc ggtcgaagac catcggcacg atgttgaaca
     1621 ccccggtgtc ggccagctcg ggcgcgcccg cgcccgccac gttgaagtac cgcaggcaca
     1681 ccgtcgcgat cccgtgggcc cggcccgtcg cgcgcaccag ccactcaccc gcgagcttcg
     1741 tctcgccgta cgggctcagg ggcgcgcacg gggtgtcctc cgtgaccagg tcggcggtgg
     1801 gcggattgcc gtagacggcg gcggacgacg agaagacgaa ccgctggatc ccggcctccg
     1861 cgacggcatc gagcagcacc gtcagaccgt gcaggttctc ccggtagtag tgcagcgggc
     1921 gctccacgga ctcgccgacc tgcttgcggc ccgcgagatg gacgaccccc gtcacctcgt
     1981 gctcggcgaa gacccgcctc agcggctcgc cgtcgagaat cgaaccgcgt acgaggggaa
     2041 tgtccgccgg gagccgctcc gggatgcccg agctgacgtc gtccaggacg accacccgct
     2101 ccccggctgc cgccagggcc ctcgtcacat gtgccccgat gtatcccgct ccgcctgtga
     2161 tcagccacgt catgggcgcc aaccctatgc gcagccctcg gtgtcgagga catgagggca
     2221 ttgcgggtat aaggggacac ggtttggagg gcgggccacc gatcgaccat gatgatcgcg
     2281 cgaccgcgcc ccggccggtc gccctgatcg gagggtaaac gggcagtgaa cgcccgtctc
     2341 acgtcatccg atagcctctg ccgacgtgcc gcccggccgc acgcaggtca tggggcgctc
     2401 ccacccaagc tgcccggcga cacgccgtgc cggcatccaa ggagtgagtt cgtctgtcga
     2461 ccgccatcct catcggacag ccggtccccg ggtcgccgct cgaaggcgat ctgcgggcac
     2521 tgggtttcga cgtgcggacc gtctccgacg cggcccaggc cgaggtggag atcgccgcgg
     2581 tgcccgcctc ggcgcgggtc gcggtggtgg acgcccgctt cgtcggccac cagcacaccc
     2641 tgcggctcgg cctcaccgac ccgcgcttcc cgctggcctg cgtacccggc gccgtcaccg
     2701 ccaagcccga ggcacgccac gaactgaccc aggcgctgac ctcccagacc catgcccctg
     2761 tggggggcca gagccccctg gagaggtggg acgggaccgg cggcccgctg cccgaccggc
     2821 tcgccgacgc cgtcgagagc gcgggcaccg ccgtgcaccg cccggagctc ggcacgctcg
     2881 tcgccgcggt ccccgaagac ccccagagcc gcaacgaggc acgccagcgc gtcgcggccg
     2941 tcgacgacga ggccgtcagg ctgcgctccg cggtcaaggc gcgcgacggc ttcttcacga
     3001 cgtactgcat cagcccctac tcgcgctaca tcgcccgctg gtgcgcccgt cgcgggctca
     3061 cccccaacca ggtcaccacc gcctcgctgc tggtcgcgct catcgcggcg ggctgcgcgg
     3121 cgaccggcac caggggcggg ttcgtcgccg cgggcgtgct gctgatcgcc tccttcgtcc
     3181 tggactgcac cgacgggcag ctcgcccgct actccctcca gtactcgacg ctcggcgcct
     3241 ggctcgacgc gaccttcgac cgcgccaagg agtacgcgta ctacgcgggg ctcgcgctcg
     3301 gcgcggcgcg cggcggcgac gacgtatggg ccctggcact cggcgccatg gtcctccagg
     3361 cgtgccgcca catcgtcgac ttctcgttca acgaggccaa ccacgacgcc caggccaaca
     3421 ccagccccac cgccgccctc tccgacaaac tcgacagcgt cgggtggacg gtctggctgc
     3481 gcaggatgat cgtgctgccg atcggtgagc gctgggcgct gatagccgta ctgacggcgg
     3541 tgaccacccc gcgcgtcacc ttctacgtcc tgctcatcgg ctgcgcgctc gccgcctgct
     3601 acaccacggc gggacgcgtc ctgcgctcgc tgacccggcg ggcccgccgt accgaccgcg
     3661 ccgcgcgggc cctggccgac ctcgccgaca gcggccccct cgcgggcggc ctcggcgcgg
     3721 cgctgcgggg cgtcgggcgc aagctgcccg ggttcggcgc ccccttcctc gccctgctcg
     3781 gcggagccgt cgtcaccgcg ctcgccgcct tcaccgactt cggaggcgtc tggccggtcg
     3841 tcggggcgct ggtctacacg ctgacctcgg cgctcgccgt cgcacggccc ctcaagggcc
     3901 ccctcgactg gctggtcccg ccgttcttcc gcgccgccga gtacggcacg atcctgctgc
     3961 tcgccgcccg cgcggacgtg aacggggcct tgcccgcggc tttcggtctg gtgtcggcgg
     4021 tcgcctacca tcactacgac acggtgtacc gcatccgcgg tggcaccggc gcgccgccga
     4081 actggctggt gcggtccgtc ggcggacacg acggcaggac gctcgtggtc accatcgccg
     4141 cggtggccct gtccgcctca gctttcaccg tcgcgctcac ggtcatcgcc gtgctcgtgg
     4201 cacttctggt gctcttcgag agcatccgct tctgggtgtc ttcgcacgca cccgccgtac
     4261 acgatgaagg agaacccgca tgatcggcct cgtgctggcc gccggcgccg gacggcgtct
     4321 gcgtccctac accgacaccc tgcccaaggc gctggtgccg gtagggcccg agggcaagga
     4381 ggacagcatc acggtgctgg acctgacgct cgggaacttc gcggagatcg gcctcaccga
     4441 ggtcgccatc atcgtcgggt accgcaagga agccgtctac gagcgcaagg cggcgcttga
     4501 gcagaagtac ggcctcaagc tcaccctgat cgacaacgac aaggccgagg agtggaacaa
     4561 cgcctactcc ctgtggtgcg gccgtgactc catccggcac acggtgatcc tcgccaacgg
     4621 cgacaccgtc cacccggtct ccgtcgagag gacgctgctc gccgcccgcg gcgacggcaa
     4681 gaagatcatc ctcgcgctcg acacggtgaa gaacctcgcc gacgaggaga tgaaggtcgt
     4741 cgccgacccc gagaagggtg tcagcaagat caccaagctg atggaccccg ccgaggcgac
     4801 cggcgagtac atcggcgtca ccctcatcga gggcgaggcc gcggacgagc tggccgacgc
     4861 cctgaaggcc acctacgagc gcgacccgca gctctactac gaggacggct accaggagct
     4921 ggtcaaccgc ggcttcaagg tcgacgtggc gcccatcggt gaggtcacct gggtggagat
     4981 cgacaaccac gacgacctgg caaagggcag ggagatcgcg tgccagtact gacgaggctc
     5041 atcccttcgc cggtagtcgt cgacatcagg cgcggggccc tggacgatct cgccgcggtc
     5101 ctctgcgacc agcggatctc cccgtcgggc aagctcgcgg tcgccatcag cggcgggtcg
     5161 ggggccaggc tgcgcgagcg gctcgccccg gccctgccgg gcgcgacctg gtacgaggtc
     5221 ggcggcggca ccctcgatga cgcgatcaag ctcgcggacg ccatgaagtc gggccactac
     5281 gacgcggtcg tggggctcgg cggcggcaag atcatcgact gtgcgaagta cgcctccgca
     5341 cggatcgggc tgccgctcgt cgccgtcgcg accaacctcg cgcacgacgg gctctgctcg
     5401 ccggtcgcga ccctggacaa cgacgcgggc cgaggctcct acggcgtgcc caacccgatc
     5461 gccgtggtca tcgacctcga cgtgatcagg gaggcacccg agcgctatgt gcgctccggc
     5521 atcggcgacg tcatctcgaa catctccgcc gtggccgact gggagctgtc ccacgccgag
     5581 acgggggaac agatcgacgg actcgccgcc gcgatggcca ggcaggcggg cgaggcggtg
     5641 ctgcgccacc ccggtgacgt cagcgacgac ggcttcctcc aggtgctcgc cgagggcctc
     5701 gtgatgaccg gtatctcgat gtcggtcgcc ggcgacagcc gcccgtcctc gggcgcctgc
     5761 cacgagatca accacgcctt cgacatcctc taccccaagc gcgccgccag ccacggcgag
     5821 caggtgggtg tgggaacggt cttcgccatg cacctgcgcg gagcccaggg cgcagccgcc
     5881 cacatggccg aggtgctgcg gcgccaccgg ctgcccgtac tgccgcagga catcggcttc
     5941 agcgtggacg agttcgtccg ggccgtcgag ttcgcgccgc agacccgtcc gggccgctac
     6001 acgattcttg agcacctcca tctgaccacc gaccagatca aggacgcgta cgccgaccat
     6061 gccaaggcca tcggtagctg aactccgccc tgtcgtccac cccgcggggg tcaaggacag
     6121 gcgcagcggt gagcactggg gcggacgtct gtacatgcga gagatctcgc tgcacatcga
     6181 cccctacctg gtgaacacca ggatcacgcc caaccagctc acgtatctga tgacggtctt
     6241 cggtgtgctg gcgtgtcccg cactgctgtg gccgggcatt cccggcgcgg tgctcggcgc
     6301 ggtgatggtc cagctctatc tgctgctcga ctgtgtcgac ggggagatcg cccgctggcg
     6361 caagcagttc tcgctcggcg gcgtctatct ggaccgggtc ggtgcctatc tcaccgacgc
     6421 ggcggtgctg gtcggcttcg ggctgcgcgg cgccgacctg tgggggagcg gccgcatcga
     6481 ctggctgtgg gccttcctcg gcaccctggc cgccctcggc gccatcatga tcaaggccga
     6541 gacggacctc gtcggggtcg cccgccacca gacggggctg ccgccggtca aggagtcggc
     6601 ctcggagcag cgctcctccg gcatggcgct ggcccgcaag gccgccgggg cgctcaagtt
     6661 ccaccggctg atcctcggca tcgaggcgtc gctgctgatc atcgtgctgg ccgtggtcga
     6721 ccagatcagg ggcgacctgt tcttcaccag gctgggtatc gcggtgctcg ccggtatcgc
     6781 cgtcgtgcag acactgctgc acctggtgtc gattctcgcg tcgagcaggc tcaagtgagt
     6841 acggacatga gtgatcccct gaaggtcggc gcggtcatca tcacgatggg cacccgcccc
     6901 gacgagctgc gcgccctgct cgactcgctc gccaagcagg agggcgggcc cgtcgaggcc
     6961 gtcgtcgtcg gcaacggttc gccggtgccc gacctccccg agggcgtgcg gaccgtcgag
     7021 ctgcccgaga acctgggcat ccccggcggc cgcaacgtcg gtatcgaggc gttcggcccc
     7081 gccggtcgcg agatggacgt cctgctcttc ctcgacgacg acggactgct cgcgggtacg
     7141 gacacggcga ggctgtgcag ggaggccttc gaggccgacc cggagctggg catcatcagc
     7201 ttccgtatcg cggacccgga gaccgggcag acggcgcgca ggcacgtgcc gaggctgcgc
     7261 gcctccgacc cgatgcactc gtcgcgggtg acgaccttcc tcggtggcgc caacgcggtg
     7321 cggacgcggg tcttcgccga cgccggcgtg ctgcccggtg acttcttcta cgcacatgag
     7381 gagacggacc tggcctggcg ggccctggac gccggctgga tgatcgacta ccgggccgac
     7441 atggtgctgc tgcaccccac gacggccccc tcccggcacg cggtctacca ccgaatggtc
     7501 gcccgcaacc gggtgtggct ggcccgccgt aatctgcccg ctccgctggt ccccgtctac
     7561 ctgggggtct ggttgctgct caccctggcc aggcgcccgt cggcccccgc cctcaaggca
     7621 tggttcggcg gattcaagga gggctggagc tctccttgcg gcccgcgccg ccccatgaag
     7681 tggcgtacgg tgtggcgcct gacccggctg ggccgcccgc ccgtgatctg acacgctttc
     7741 tacggagggc cgcggacaca ctgccgtggt cgtccctcac tccgcccacg cccaagaggc
     7801 tgcgcacctt gaagacgaaa gtttccgctt gtgagtgaca caacgcagga cggcggtgtc
     7861 gcgttgacca ccccgccgtc acccgacgcc gggctctccc gccccgagct ggccgccaag
     7921 tacggcctga cggtgagcgg cgcgaggccc ggactgttcg agtacgtacg ccagctctgg
     7981 ggccggcgcc acttcatcct ctccttctcg caggcgaagc tcaccgccca gtacagccag
     8041 gccaagctcg gccagctctg gcaggtggcg accccgctgc tgaacgcgct cgtctacttc
     8101 ttcatcttcg gcctgctgct cggggggagg aagggcatcc cgcacaacgc ctacgtgccc
     8161 ttcctcgtga ccggcgtctt cgtcttcacc ttcacccaga gctccgtgca ggcgggtgtg
     8221 aaggccatct ccggcaacct cggcctggtc cgcgcgctgc acttcccgcg cgcctcgctg
     8281 cccatctcgt tctcgctcca gcagctccag cagctgctgt tctcgctgat cgtgctggtc
     8341 atcgtgatgg tcgggttcgg gtactacccg gacctctcgt ggctgctggt gattcccgcc
     8401 ctcgcgctcc agctcgtgtt caacaccgga ctcgcgctgg tcttcgcccg catgggcgcc
     8461 aagacacccg acctcgccca gctcatgccg ttcatcatgc gtacctggat gtacgcctcc
     8521 ggggtcatgt tctccatccc ggcgatgctg gccaccaagg acgtgccgag ctgggtgagc
     8581 gatgtgctcc agtggaatcc ggcctcgatc tacatggacc tgatccgttt cgcgatgatc
     8641 gacgactacg ggcccaagta cctgcccccg catgtgtggg ccttcgcggc ggcttgggcc
     8701 gtggtgatcg gcatcggcgg ctttgtgtac ttctggaagg cggaagagcg gtatggccgt
     8761 ggctgaggac aagaacgacg ggcgggccca catcccgacc gtcatcgccg acgaactcca
     8821 catcgtctac cgggtcaacg gcggtggccg tgccaagggc ggcgccaccg ccgcgctcag
     8881 ccgcatcgtg cggcgcggcg gcgagtcgcc cggtgtcaga aaggtgcacg cggtacgggg
     8941 tgtctccttc acctcctacc ggggcgaggc catcgggctg atcggctcga acggttcggg
     9001 caagtcgaca ctgctgcgcg ccatcgcggg actcctgccg gccgagaagg gacgggtcta
     9061 caccgacggg cagccctcgc tgctcggtgt gaacgcggcc ctgatgaacg acctgacggg
     9121 cgagcgcaac gtggtcctcg gcggtctcgc catggggatg acccgggagc aggtcaagga
     9181 gcgctaccag agcatcgtgg acttctccgg catcaacgag aagggcgact tcatcacgct
     9241 gcccatgcgt acctactcgt cgggtatggc cgcccggctg cggttctcca tcgccgcggc
     9301 caaggaccac gacgtactga tgatcgacga ggccctggcc accggcgacc gcaagttcca
     9361 gaagcgctcc gaggccagga tccgcgagct gcgcaaggaa gcgggaacgg tcttcctcgt
     9421 cagccacaac aacaagtcga tcagggacac ctgcgaccgg gtgctgtggc tggagcgtgg
     9481 cgagctgcgt atggacggcc ccacggacga ggtcatcaag gagtacgaga agttcaccag
     9541 caagtagccg tccgcggccc cgtgcaccgg ggccgcggac atcggcggtg ccccgcggga
     9601 gtgttctccg gcggggcact ggtgcattcg ggctcataac gagtggcgtg gggcgcctgt
     9661 gctgtgatgt gctccggcgg cgcgtggtca aggagaggtc aacttccacc cggtccggga
     9721 aggttgacga caatcggtgt gttgttgtga cgtacggatc accccgcgtg ggagcgcgga
     9781 gttgtacaac gtaagctgtg ccggtgctga atcgcgacga gtggggcgat accgcgcaag
     9841 ggccctgggc tgggtcgatc cgctcggtga gcggtttggc ggcgtgtccg aaatgggttg
     9901 ctttgcgtcg gcggtgtaga acgggagatg tgacggcaat ggctcaggat gatctccggc
     9961 ttcgcgctgc atccgccgtc ctcgtgctcg gcggcagaag gtgagggcgg acaggggtac
    10021 gaaccccggc gccccggcgc gagacacgct cggaaaggcc gcggacgaga actttccggt
    10081 ggccccgttc ttcctgccgc gcgcctggcg cgacgatctg atggccgttt acggattcgc
    10141 gcggctcgtc gacgacatcg gtgacggcga cctcgccccc ggtggcgccg acgcccgcca
    10201 tctgggggtc ggcccgctgg aggcggacga ccggctggtc atgctcgacg cgttcgagac
    10261 ggacctgcac cgcgtcttcg acgcctcggc cacacctcac cacccgctcc tgcgtgcgct
    10321 gcgtcccacc gtccgccgct gcggactcat ccccgacccc ttcctcgcgc tgatcgaggc
    10381 gaaccgccag gaccagcgcg tcagccgtta cgccacctac gaagaactgc gcgcgtactg
    10441 tgagctctcc gccaatccgg tgggacggct ggtgctcggc atcacgggga cggagagcgc
    10501 cgagcggatc cgccgctccg acgccatctg caccgcgctt cagatcatcg agcatctcca
    10561 ggacgtgagc gaggacctga ggcgggatcg cgtctacctg cccgccgagg acatgacccg
    10621 ctttcacgtc acggaagccg atctggcggc ccccacgggg ggcgcgtcgg tgcgcgcgct
    10681 ggtcgcattt gaagtggaac gcgcccacga gctgctgaat gaagggatgc cgctggtggg
    10741 tagcgtccac ggcaggctca agctactgct cgccggtttc gtggccggag ggcgagcggc
    10801 cctcgtggcc gtgagggacg cgggccacga cgtacttccc aggccgccga agcccaccaa
    10861 gctcaggctg ctgcgcgagg tgggagcgac tctgcgagga gaagggtgag cccgacgatg
    10921 gaagagacgc aaggcctgtc agcacctgta ctcgccgcgt acagctactg cgagaccgtc
    10981 acgggccagc aggcacgcaa cttcgcctac ggcatccggc tgctgccgcc gcccaagcgg
    11041 cgagccatgt cggcgctgta cgcgttctcg cgccgggtgg acgacatcgg cgacggaacc
    11101 ctggagcctg agatcaaggc ggcgaggctc gacgagacac gcacgctgct cggccgggtc
    11161 aagaacggct ccgtgcagga ggacgacacc gaccccgtcg ctgtcgcact gacccacgcg
    11221 gcgacacatt tccccctgga cctcggggga ctggacgaac tcatcgacgg cgtcgtcaag
    11281 gacgtgcgcg gcgagaccta cgagacctgg gacgacctca aggtctactg ccgctgcgtc
    11341 gccggagcca tcggccgcct cgcgctcggc gtcttcggca cggagccggg ggtcagggac
    11401 acggagcgcg ccgccgagta cgccgacacc ctcggcctcg ccctccagtt gaccaacatc
    11461 ctgcgtgaca tccgcgagga cgccctcgac ggcaggacct atctgcccgc cgacgacctc
    11521 ggcaaattcg gctgctccgc cgggttcgcg ggcaccgtgc cgccccccgg ctcggacttc
    11581 gccggtcttg tgcacttcga agccaggcgc gccagggagc tgttcgccga gggctaccgc
    11641 ctgctgccca tgctcgaccg ccgcagcggc gcctgcgtcg ccgcgatggc cggcatctac
    11701 cgcaggctgc tcgaacggat cgccagggaa ccggaagccg tactgcgcgg cagggtctcg
    11761 ctgcccggcc acgagaaggc gtacgtcgcc gtccgcggac tctcgggact cgacgcgcgc
    11821 aacgtctccc gtaaaaccct cggggggcgt gcatgaccga cgcgacggcg gcggaaagac
    11881 tccagctcat ggccgtttcg acggtccgcg gccacgcctt cgcggtttcg cacgaacggt
    11941 gggcaaccct cagggagcgg cccgcgtccc tgtcagcggc ggccccctgt cagtgcgtcg
    12001 caccgggggc cacgggggag ggcacatgag cgggcagcga acacggcccc gcgacccggc
    12061 cgacgaccac gcggtggtcg tcggcggagg actcgcgggc gtcaccgccg cactcggact
    12121 cgccgactcg ggaatgcggg tgaccctgat cgagggaaga ccccgcctcg gcggcctcgc
    12181 cttctccttc cggcgcggcg acctcaccgt cgacaacgga cagcacgtgt atctgcgctg
    12241 ctgcaccgcc taccaggact tccttcgccg gatcgacgga ctggccctcg cccccgtgca
    12301 ggaacgtctc gacgtgcccg ttctggacgc cgggaccaac cgcctcggcc ggctgcggcg
    12361 caacgcgctg cccgtccccc tgcacctcgc cgcgggcctc gcgcgctatc cgcacctctc
    12421 cctcgccgaa cgcgccgccg tcgggcgcgc cgcgctcgcg ctgaagaaac tcgaccccgc
    12481 cgacccggcc ctcgacgaac aggacttcgg cagctggctg gcgcgccacg ggcagtcgcc
    12541 gcgcgccgtc gaggcgctct gggacctcgt cggcgtcgcc accctcaacg cccgcgcggg
    12601 cgatgcctcc ctcgccctcg ccgccaaggt cttccgcaca gggctgctct cggaacccgg
    12661 cgcggccgac atcggatggg cccacgtccc gctcggcgaa ctccacgaca cactcgcccg
    12721 ccgcgccctc gacaaggccg gggtccgcac cgaactgcgc accagggcca acaccgtctc
    12781 ccgcaccgag gagggcggct ggcgggtcgt caccgacaag gagaccctcg acgcgggcac
    12841 ggtcgtcctc gccgtacccc agcgcgagac ccacgccctg ctccccgacg gcgccctcga
    12901 cgaaccgggg ctgctgctgg aactgggaac ggcgcccatc ctgaacgtgc acgtcgtcta
    12961 cgacaggaag gtgctgcgcc ggcctttctt tgccggactc ggcacccccg tccagtgggt
    13021 cttcgaccgc accgccgcct ccggcctcga acagggccag tacctcgccc tctcccagtc
    13081 cacggcccac gacgagatcg acgcgcccgt cagcgcgctg cgcgagcgct acctcccaga
    13141 actggaacgg ctgttgcccg ccgcccgcgg cgcccaggtg aaggacttct tcgtcaccag
    13201 ggaacgtacc gcgaccttcg accccgctcc tgggaccggg cggctgcggc cgggcaccag
    13261 gaccagggcc cccggcctct acctggccgg agcgtggacc gccaccgggt ggcccgcgac
    13321 catggagggc gccgtacgaa gcggcgccgg tgccgccgcg gcggccctcc gcactctggg
    13381 ccgtgcccac gaccatctct tcgaggaggc cgcatgaggc tcgatctcct ggggccaggc
    13441 ccccagaacc ccagcagcac cggaacaagc agcaccggaa caagaggaga gactgtgccg
    13501 actgtgccct cggccgattc ggctgccgac gccgcggacg tgaccgcgct cctggagcgt
    13561 ggccggaccc tggcgacgcc ggtgctgcgg tccgccgtgg accgtctcgc gccgcccatg
    13621 gacaccgtcg ccgcctacca cttcgggtgg atcgacgcgg acggcaggcc cgccgagggc
    13681 gacggcggaa aggcggtacg cccggcgctc gccctcatct cggccgaggc cgcgggcgcc
    13741 ccgccggaga cgggcgtacc cggcgccgtc gccgtggaac tcgtccacaa cttctccctg
    13801 ctgcacgacg acctgatgga cggcgacgaa cagcgccgcc accgcgacac cgtgtggaag
    13861 gtgcacggcc ccgcccaggc gatcctcgtg ggcgacgcgc tcttcgccct cgccaacgag
    13921 gtgctgctgg aactcggcac ccccgaggcc ggacgcgcca cgcgccgcct caccacggcc
    13981 acccgcgccc tcatcgacgg gcaggcccag gacatctcct acgagcaccg cgagcgcgtc
    14041 agcgtcgagg agtgcctgga gatggagggc aacaagaccg gcgccctgct cgcctgcgcg
    14101 gtctccgtcg gcgccgtgct cggcggcgcc gacgaccaca ccgccgacac cctggagaag
    14161 tacggctacc acctgggcct cgcgttccag gccgtcgacg acctcctcgg tatctggggc
    14221 gatccggagt ccacgggcaa gcagacctgg tccgatctgc gccagcgcaa gaagtccctg
    14281 cccgtggtcg ccgcactcgc ggccggaggc gcggcctccg acaaactggc gggactcctc
    14341 gccgccgacg cggggaccga tgaccccgcg gccttctccg aagaggagtt cgccgcgcgc
    14401 gccgcactga tcgaagaagc gggcggccgt gagtggaccg cccaggaggc gcgcaggcag
    14461 cacacggtcg ccatcgaggc gctcgacgcg atcacgctgc ccgaccacgt gcgggcgcag
    14521 ctcgtggcgc tcgccgactt cgtagtagtc cgaaagagat gatcaccatc cgacatcaca
    14581 ggtacatata acgcgcagtc gccgaccggc ggcccggcct ccgtgctcca cctgccccca
    14641 ggcggcaggc tccccagggg caaggccggg cactggtcga cggcggaccc acagcagagg
    14701 tactgactgc acgaagggga agccatgaca gcgacgaccg acggaagcgc cggggcggta
    14761 tcgcccgaag cggcctcggc cagtgcacca cccgacccgt cccccggcgt cgcgggcccg
    14821 cgtgagaccg cggaacgcgc cacccggcgg gccgtcgagt tcctcctgtc caaccaggac
    14881 gaacagggct ggtggaaagg cgatctcgcc accaacgtca ccatggacgc ggaggatctg
    14941 ctgctccggc agttcctggg catcagtgac gagaagacca cgcgtgccgc ggcgctcttc
    15001 atccgcggcg agcagcggga ggacggcacc tgggccacct tctacaaggg ccccggcgag
    15061 ctctccacca ccatcgaagc gtacgtggcg ctccgcctcg cgggtgacag ccccgaagcc
    15121 ccccacatgg cgaaggcctc ggcctgggtg cgcgagcggg gcggggtcgc ctcggcccgc
    15181 gtcttcaccc gcatctggct cgccctgttc ggctggtgga agtgggacga cctgcccgag
    15241 ctgccgcccg agctgatgtt cttccccaag tggatgccgc tcaacatcta cgacttcggc
    15301 tgctgggcca ggcagacgat cgtgccgctc accgtcgtct ccgccatccg tcccgtgcgc
    15361 cccgcgccgt tcgccctgga ggagctgcac accgacgcgg ccgtgcccaa cccggccgtc
    15421 cccttcgcac ctgtggccag ttgggacggc gccttccagc gcctggaccg ggtcatgcac
    15481 ggctaccgca agttcgtccc gcgccgactg cgcaggaccg cgatgaacgc ggcggcgcgc
    15541 tggatcatcg aacgccagga gaacgacggc tgctggggcg ggatccagcc ccccgccgtc
    15601 tactcggtga tggcgctgca ccttctcggc tacgacctgg accaccccgt gctcaggacc
    15661 ggcctggagt cactggacag gttcgcggtg tggcgcgagg acggcgcccg gatgatcgag
    15721 gcctgccagt caccggtctg ggacacctgc ctcgccacca tcgccctggc cgacgcgggc
    15781 gtcgcccccg accacccaca gctcgtacgg gccgccgact ggatgatcag cgaacagatc
    15841 accaggccgg gggattggag cgtccgcaga ccgggccttg tctccggcgg ctgggccttc
    15901 gagttcgaca acgacaacta cccggacatc gacgacacgg ccgaggtcat cctcgccctg
    15961 cgccgagtgg cccaccccga caaggcggcc gtcgaagcgg ccgtgcgccg cgcggccgag
    16021 tggagcgccg ggatgcagtc gaggaacggc ggctggggcg ccttcgacgc cgacaacacc
    16081 agcccctttc ccaaccggct gcccttctcc gacttcggtg aggtcatcga cccgccgtcg
    16141 gcggacgtca ccgcccacat ggtggagatg ctggcgctcg aagggctggc gcaccacccg
    16201 cgtacccggc gcggcgtcga gtggttgctc gccgagcagg aggccaacgg ctcctggttc
    16261 ggccggtggg gcgtcaacta cgtctacggc acaggtgcgg tcgtccccgc cctcaccgcg
    16321 gcggggctcc cgctctcgca ccccgccatc aggcgcggtg tcgaatggct ggagtcggtg
    16381 cagaacgacg acggcggctg gggcgaggac ctgcgctcct acgacgaccc ttcctgggcg
    16441 ggccgcggcg cctccacggc gtcccagacc ggctgggcgc tcctcgccct gctcgccgcg
    16501 ggtgagcgcg agtccaaagc ggtcgagcgg gcggtcacct acctggccga gacccaggcc
    16561 gcgaacggca cctgggacga gccgtacttc accggcaccg gtttcccctg ggacttctcc
    16621 atcaactacc acctctaccg gcaggtcttc ccgctgaccg cgctgggacg ttacgtccac
    16681 ggggcagccc cagaggactc ctgatgagca agttctcggg cgcggacggc ggcgcccgga
    16741 acccgtcacc gctgctgatc gcgtgtgcgc tcggcatcga gcagctcgcg ctgcgcagcg
    16801 gtgaccgcaa gagcgcgcgg ggacccgtca ccgtcctgcg gacgggcatg gggccccgcg
    16861 cggccgagcg cgccatcaca cgcgcgctcg gcgacggacg cggcgccaac accgcggtcg
    16921 tcgccaccgg cttctgcgcg gggctcgaac cgggaatgca ccccggtgac ctcgtcgtcg
    16981 cggaagagac ccgggacgca cggggcacca ccccgtgtgc gggcaccgca ctgctggccg
    17041 acgcggtcgc ccgcgccgtt cccggccgcg cggtacacac cggccccctg gccggctccg
    17101 accatgtcgt acgcgggcag gagagagccg agctgggagc gaccggcgcg gtcgccgtgg
    17161 acatggagtc cgccgcgacg ctccgcagcg ccctcgccgt cggcccgcgt ccggttgccg
    17221 ccgtacgggt ggtcgtggac gctccggagc acgaactcgt cagaatcggc acggtacgcg
    17281 gtggaatatc ggccttccgt gttctccgtg ccgtcctacc agctttctat gaatggcacc
    17341 gttctttgct gctccccagg aggtgagcta gatggccatg ccgctccgcc agaccatcag
    17401 ggtcgggacg tatctgatgg aacagaagct ccgcaagcgg acgaagttcc cgctgatcgt
    17461 cgagttggaa ccgcttttcg cctgcaatct ggcctgtgag ggctgtggga agatccagca
    17521 cccggcaggg gtcctgaagc agcgcatgcc ggtggcccag gccgtcggcg ccgtactcga
    17581 atcgggcgca ccgatggtct ccatcgccgg tggtgagccg ctgatgcacc cacagatcga
    17641 tgaaatcgtg cgtcagctcg tggcgaagag gaagtacgtc ttcctctgca ccaacgccat
    17701 gctgatgcgc aagaagatgg agaagttcac cccgtcgccg tatttcgcct tcgccgtcca
    17761 catcgacggc ctgaaggagc ggcacgacga gtccgtcgcg aaggagggag tgttcgacga
    17821 ggcggtggcc gccatcaagg aggccaagcg gcgtggattc cgtgtcacca ccaactcgac
    17881 cttcttcaac acggacaccc cgcagaccat catcgaggta ctcgacttcc tcaatgacga
    17941 tctgcaggtc gacgagatga tgatctcgcc cgcctacgcc tacgagaagg ctcccgacca
    18001 ggagcacttc ctcggggtcg aacagaccag ggaactgttc aagaaggcgt tcgccggcgg
    18061 gaacaggggc cggtggcgcc tcaaccactc gccgctcttc ctcgacttcc tggagggcaa
    18121 gaccgactac gactgcacgg cctgggcgat cccgaactac tcgctcttcg gctggcagcg
    18181 tccctgctac ctgatgagcg acgggtacgt cccgacgtac cgtcaactca tcgaggagac
    18241 cgactgggac aagtacggcc gaggcaagga ccctcggtgt gccaactgca tggcgcactg
    18301 cggttacgag ccgaccgcgg tgctcgccac catggggtcg ctgaaggagt ccatccgcgc
    18361 ggcacgggag accgtctccg gaaaccgcgg ctgatcgcgt gacgcggggg ccggccccct
    18421 ccgggggagt cggccctgtc cggcctcagg gccgcgtgac cgccgagggt cacccgacag
    18481 cctctccggc caccgccacg agctgtaacg gctcatcgcc ctcacgacgt gagccgaacg
    18541 tccccatgag aggggggccc gagcgtgaca ctgcttgaaa ccatccgggg gccgcgcgac
    18601 ctgaaggcgc tggggcagga ggaggtccgt gaactggccg cggagatcag agagttcctg
    18661 atccaggcgg tgtccaagac cggcggccac ctcggcccca acctgggggt ggtggaactc
    18721 accctcgccc tccaccgcgt cttcgagtcg ccccgcgacc gcatcctgtg ggacaccggc
    18781 caccagagct acgtccacaa actgctcacc gggcgccagg acttctccaa gctccgcaag
    18841 aagggcggcc tctccggcta cccctcgcgc gccgagtccg agcacgacgt catcgagaac
    18901 tcgcacgcct ccaccgtcct cggctgggcc gacgggctcg ccaaggcccg tgacgtacaa
    18961 ggcatgcagg ggcacgtcgt cgccgtcacc ggcgacggag ccctcaccgg cgggatggcc
    19021 tgggaggcgc tgaacaacat cgccgccgcc aaggaccagc ccctgatcat cgtcgtcaac
    19081 gacaacgagc gctcctacgc gccgaccatc ggcggcctcg ccgaccacct cgccaccctg
    19141 cgcgtcacca acggttacga gaaggtcctc gcctggggca aggacgtact cgaccgcacc
    19201 cccgtcgtcg gcagaccgct ctacgagtcg ctgcacggcg cgaagaaggg gttcaaggac
    19261 gccttcgcgc cgcagggcat gttcgaggac ctgggcctca agtacctcgg ccccttcgac
    19321 ggccatgaca tggaggcggt cgagtcgggg ctgcgccgcg ccgcccggtt cgagggcccc
    19381 gtcatcgtgc actgcatcac cgagaagggc aggggctacg agcccgccct gcggcacgac
    19441 gccgaccgct tccacacggt cctcgcgatg gacccgctga cctgcgaacc cctcacaccg
    19501 tcagggccgc cctcgtggac ctccgtgttc agcgacgaac tggtcaggat cgccgaggaa
    19561 cgcgacgaca tcgtcgccct gacggccgcc atgctcgacc ccgtggggct cacgcccttc
    19621 gctgagcggt tccccgacag gatctgggac gtcggcatcg ccgagcagca cgccaccgtc
    19681 accgccgcgg gactcgcgac cggcgggctg caccccgtcg tcgccctgta cgccaccttc
    19741 ctcaaccggg ccttcgacca actgctgatg gacgtggccc tgcacaagtg cggcgtcacc
    19801 ttcgtcctcg accgggcggg tgtcacaggg gccgacggcg cctcccacaa cggcatgtgg
    19861 gacatgtccg tactccaggt ggtgcccggc ctcaggatcg cggcgccccg cgacgccggc
    19921 cagctccgcg cccagttgcg tgaggccgtc gacgtccacg acgcccccac cctcgtgcgc
    19981 tatcccaagg agtccgtggg cgaggatatc cccgccgtcg gcacggtcgg ctccatggac
    20041 gtcctgcacc gcgcggagag cgccgaagtg ctgctggtcg ccgtcggtgt gatggccccc
    20101 gtctgtctcc aggcggcgcg gctcctccag gaccgcggga tcggcgccac cgtcgtcgac
    20161 ccccgctggg tcaaacccgt cgaccccgaa ctgcccgcgc tcgccgcggc acaccgactg
    20221 gtggccgtgg tcgaggacaa cagccgtgcc tcgggtgtgg gcgcggcggt cgcactggcc
    20281 ctcggcgacg ccgaggtcga cgtgccggtg cggctcttcg gcatccccga ccagttcctc
    20341 gcgcacggca agcgcggcga actgctcgcc gatctcggac tcacccccgt ggagatcgcg
    20401 gggcggatcg gggccaccct ggaccgcaag ggggccgggg cggagaccgg ggccaccctg
    20461 gaccgtaagg agaacgaaga agcatgacga tcggcaccag tggcaccacc ggtgaggaga
    20521 gcggcgcggc gacgaagggg ttcgacctcg ccacgctgct cgcggagcgc ggcggcgaac
    20581 gctatgacct gcacacgcgc tacctcaacc accagctccc gcgcatgctg cacaccatcg
    20641 gcttcgacaa ggtctaccag cgtgcggagg gcgcctactt ctgggacgag gacggcaacg
    20701 actacctcga catgctcgcc ggcttcggcg tcatgggact gggccgtcac caccccgtcg
    20761 tacgcaaggc gctgcacgac gtactcgacg cctcgctggc cgacctgacc aggttcgact
    20821 gccagccgct gcccggcctg ctcgccgaga agctgctcgc gcacagcccc cacctggacc
    20881 gggtgttctt cggcaacagc ggcaccgagg ccgtggagac cgcgctgaag ttcgcacggt
    20941 tcgccacggg caggaaacgt gttctgtact gcacgcacgc cttccacggt ctgaccacgg
    21001 ggtccctctc cgtcaacggg gagaaggggt tcagggaggg cttcgcgccg ctgctgcccg
    21061 acacaccgat tccgttgggc gacctggacg cgctggagaa ggagctgaag cggggcgacg
    21121 tcgccgggct catcgtcgaa cccatccagg gcaagggcgt gcacaccacc ccgcccggct
    21181 atctgcgcgc ggcccaggaa ctcttgcgca agcacaaggc gctgctgatc gccgacgagg
    21241 tgcagacggg gctcggccgg acgggcgact tctacgccta ccagcacgag gaaggtgtcg
    21301 aacccgatct cgtctgcgtc gccaaatcac tctccggcgg atatgtgccg gtcagcgcca
    21361 cgctcggcaa ggactggatc ttcaagaagg tctactcgtc gatggaccgg gtcctcgtcc
    21421 actccgccag tttcggcgcc aacgcccagg cgatggcggc ggggctcgcc gtgctcggcg
    21481 cgatggagga cgagaacatc gtcgccaacg cccgcagctc cggcgaactg ctgaggaacc
    21541 gtctcgcgga gctgatcccg cgctacgaac tgctcgccga tgtccgcggg cgcggcctca
    21601 tgatcggcat cgagttcggc aggcccgact cgctcaagct ccgcagccgc tggacggtgc
    21661 tccaggcggc gcgcaaggga ctgttcgcgc agatggtggt ggtgccgctg ctccagaaac
    21721 accgcatcct cacccaggtc tccggcgacc acctcgaagt gatcaagctg atcccgccgc
    21781 tggtcatcgg cgagcgcgag gtggacaggt tcgtggcggc gttcaccgcc gtcatggacg
    21841 acgcgcacaa cggcggactg atgtgggact tcgggaagaa tctgatgaag caggccgtcg
    21901 ccaaccgctg acccccttcg cgcgccggat cgggccgggc cgcctccacc cacagggggt
    21961 gggcccggcc cttttgcctg cgaggcaata aatttgcccg tgaggaaagg ttctggctga
    22021 atcgacggta tgagtcccgt cgattccgtc gattccgtcg atcccgtcga ttccgtcgat
    22081 tccggcggtc gtcccgctga tcccctcggt gcggtcggtc cagccgattc tctcggtccc
    22141 gcggatccgg tcgatcccgt cggccccgtc gatcccgtcg gccccgtcgc gccggagccc
    22201 ggcgtcgagg ccgacgcgcc ctccgacgct cagggcgaga cctcggccgg cctcggtgag
    22261 ctgcccgccg tcgctcccaa actacgcgaa ctgcgccgca cggccgggct gaccctggaa
    22321 gcggcggccc gcgcggccag cctctccccg gcccacctct cgcggctgga gacgggccga
    22381 cgccagccgt ccctgcccat gttgctcgcg ctctccagga cctacggtac gaccgtctcc
    22441 gaactcctgg gcgagagcac cgcggaccgg gacgccgtgg tccgcggcgg ggacacggag
    22501 cccacccgcg cgggcggctg gacctactgg caggcgggcg gccagggacg cggcatgcag
    22561 acgctgcgcg tccacgtccc gcacggggcc cagggcgaca tggtgcgggt gcacccgggc
    22621 gaggaatggc tctacgtact gggcggccgg ctcaggctgc gcctcggtga cagtacgcat
    22681 gtcctcaagc cgggggacag cgcccacttc gactcgctca ccccgcaccg gatcgccgcc
    22741 gccgaccagg gcggcgccga tctcctcttc gtccacaccc tcatgcagag ccccgtcacc
    22801 gcgctgtgtc tcggcgacgg caacccggga ggcgcctgat gtccgacgcg agcacgaacg
    22861 acgaaaggac cgcgagcacg aacgacgaaa ggaccgcgac ggccggcggg accccggccg
    22921 cgggcgccac gcccctgacc gacgccactc ctgggcaggg cgccgacgcc agcaccggac
    22981 agggagaccc cgtggctccg atgcgggagg agcccgcccc gatgcgcgtg gagcccgtca
    23041 agagccgttc gatcgaggac aagctgccgc gcggcctgtg ggtacggctg ttcgcctaca
    23101 tcatcgcggg ccatctcgtc gccgcgttcc tgtacctgct cttcaccctc ggggagcaca
    23161 gccagtgaca ccgtccgggc acgcggtcgc tgacgcggta cgcgccccgc gagtgccgtg
    23221 gctcagctct ccacgagctg cccgcgcaac gtcccgcgca gctccggggt cagtcccagg
    23281 ccttcctcga agtagcggtc cgtggagccc caggtctcct cgatggtctc cagcgccgcg
    23341 tgcaggtact ccgcgcgggc ctcgaagagg ggattgagca gctccatcac ctcgggcgac
    23401 ataccgccgg gcgcgtcgct gtcccgccgc accttgtagc ggcggtgcgg ggcgttcgac
    23461 ttgaggtagt cctcctcgat ggccccgggc tcggccccga ccgccagcag gacgatcgcg
    23521 atggacatgc ccgcacggtc cttgcccgcc gcgcagtgca gcagcgcggg cacactgtcg
    23581 cccgccagcg cgcggagcag ttcaccgtgt tgcgcggtct tctccgtgat caccgaccgg
    23641 taggtgtccg tcatccgggt cgccgccctg ccgtcgccga gcaacgcgtg caactggccg
    23701 atgtcgccgt tccgtaccag cttccagaac cccgcgccgt ccgccgggtc gttcagcggc
    23761 atgctgacat tgcgtacgcc gggcaggtca acgtccttgc cctcaagggc ctggtccgcc
    23821 gcgttgcgga agtcgaagac ggtgtgcagg ccgagcgacg acaggaaagc ggtgtcggag
    23881 gcggtggcgt gtgcgagatg gccgctgcgg aagagccgcc ccgccctgac ccgcccgccg
    23941 tccacggtcg gtattccgcc cacatcacgg aagttgcgta cggcttccag ctcgggctct
    24001 gcctgcggcg ggacctgctg tgtcacgggg gctccttcca ttcggccccc ggcgctcctc
    24061 gcaggtcggg cggcgcaccc gaccctacga caccacttcc gcggccggac aggcccgtga
    24121 gggccccggg tgagcagcgt catagccgtg acgctccgtg gcgaatggcg cgaggtgaat
    24181 tcgttccgcc gtctccatta cggagatccg gaatggacgg agtgtgaccg ctttccattg
    24241 aaaagatcaa ggaattcaat gggatgggtg aattcgcagc ttgtctccgg ccattccgct
    24301 cgtttacggt caccgtcaat ccggccggaa cgccaaatcc tgccgccgac cggaattctt
    24361 tcacccaccc gtacccggca ggagcggggg acccaggcaa cacgccgtga ccgggatttc
    24421 cccgggcggc tcggggtgaa gccgtgtcct cgacacggcc gggcacctcc agcccgaacc
    24481 cgacagctca cctcgtaggc gacggagagg aattccccat gcccgcaacg ggtaagcacc
    24541 gtcgttccag ccgccgtctc agccgtggtc tcgccgtcgc gaccaccggc ggagccgtcg
    24601 tcgccctgcc gctgctcggc gcggcaggcg cccacgcggc cacccctgcc gccgccccgc
    24661 agaaggcgga gaccacctac tcggtggccg ccggtgacac gctggccaag atcgcccgcg
    24721 accaccacgt gagcggcggc tggcagaagc tctacgaggc caaccacaag gcggtcggct
    24781 ccgacccggc caagatcaag ccgggcatgg agctgaacct cgtggtcgcc tccgccgcca
    24841 aggcgccggc caccggctcc acgcagagcg gcagcggctg gcaggccccg gtcaaggcgt
    24901 ccatcggtac cggctaccag gcctccggcg gcagctggtc cagcggccac cacaccggca
    24961 tcgacttcct cgtcggctcg ggcacctccg tgaaggccgc cgccgccggc accgtcgtcg
    25021 ccgcgggcga cggcggcgcg tacggcaacc aggtcgtcgt ccaccacgcc gacgggcact
    25081 acacccagta cggccatctc tcgtcgatct ccgtctccgt gggccaacag gtcagcgagg
    25141 ggcagcagat cgccctctcc ggcgccaccg gcaacgtcac ggggccgcac ctgcacttcg
    25201 aggtcaggac cggccccgac tacggctcgg acatcaaccc gctcgacttc ctgcaccagc
    25261 acggagtctc cgcctgacct gacaggcgcc cgattccccg ccccacctga cgggcggcgg
    25321 ctgggcacac ccgccgtgcg ggccggtcct tcggccacga cggatcgccc cgcacctcgg
    25381 tcgcggccgg ccccttatgc gagggaccgg ccgcgatcac ggctgtttcc cgcctattcc
    25441 gtaattggaa gaaacttgac ggtggctttt ctcacccacc gtcaacctct ccttacggtg
    25501 gcgtaggtca cttctccggg tgaatgatgt gtgtgtggca caggtatcga ggtttcccag
    25561 taatcccgtc attcggtcct acgcggctgt cggcgacagc ttcaccgaag gtgtaggcga
    25621 cccggggccc ggcggtggct acgtcggctg ggccgacagg ctggcggtcc tgttggccga
    25681 ccggctcccc gagcacacct tccgctacgc caacctcgcc gtacgcggga aactgctcga
    25741 ccagatcgtg gccgggcagg tggcccgcgc caaggaactc gcccccgacc tcgtgacctt
    25801 cgccgcgggt ggcaacgaca tgctgcggcc cggcgccgac ccggacgacg ccgccgaacg
    25861 gttcgagcgg gccgtcgccg acctccgcga ctccgtcggc acggtcatgg tgaccacggg
    25921 gttcgacacc agggacaccc cggtcctgcg ccggctgcgc ggcaagatcg ccacctacaa
    25981 cgaacacgta cgcgcggtgg ccgaccggta cggctgcccc gtgctcgacc tctggtccct
    26041 gaagacgatc caggaccgcc gcgcctggga caccgaccgg ctgcacctct ccgctgaggg
    26101 ccacacccgt gtcgcactcc gagcgggcct ggtactcggc ctcgaagttc ccgccgaccc
    26161 cgaccagccc tggcctccac tgcccccgcg cggcaccctc gaagagcggc gcgacgacat
    26221 cacctgggcg cgcgagtact tggtgccgtg gatcggcaga cggctgcgcg gcgagtcctc
    26281 cggtgaccac gtggtcgcca agcggcccga cctgcttccg ctgtaggagt gcgggggctg
    26341 taggcgcggg cggccgaggc atccctcggc gcctcggcca gacacgtcga ctcggtccct
    26401 cggcgcctcg gcgggacacg tcgactcggc gccggagccg gatccccgct cctcaaccgg
    26461 gcccccgctc ctcaaccgga cccccgctcc tcaaccggag cccgtcgtct ccacaaccgg
    26521 gggccgtccc ctgatccgaa gccgtcccct tgacctgggg tcgtcccctt ggctcggggc
    26581 cttccccttg acccgggccg ggtgttcaac tcggggcagg gtgtccgccg cggggcgtcc
    26641 accactcgac gagcccccac accccgaggg cgagcgcggc cgcggccacg agcgccgcgg
    26701 ccca
//
