LOCUS       NZ_CP045096            25218 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces phaeolivaceus strain GY16 chromosome, complete genome.
ACCESSION   NZ_CP045096
VERSION     NZ_CP045096.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces phaeolivaceus
  ORGANISM  Streptomyces phaeolivaceus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10116136)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain GY16 isolated from leaves of Broussonetia
            papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10116136)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-AUG-2019
            Assembly Method                   :: HGAP v. v. 1.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009184865.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:51:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,113
            CDSs (total)                      :: 9,024
            Genes (coding)                    :: 8,642
            CDSs (with protein)               :: 8,642
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 382
            CDSs (without protein)            :: 382
            Pseudo Genes (ambiguous residues) :: 0 of 382
            Pseudo Genes (frameshifted)       :: 112 of 382
            Pseudo Genes (incomplete)         :: 305 of 382
            Pseudo Genes (internal stop)      :: 23 of 382
            Pseudo Genes (multiple problems)  :: 53 of 382
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4997278
            Orig. end                         :: 5022496
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045096.1.
            Bacteria and source DNA available from Yunlin Zhao.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25218
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="18"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25218
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25218
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15218](-)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15218)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            334..1989
                     /locus_tag="F9278_RS23615"
                     /old_locus_tag="F9278_23630"
     CDS             334..1989
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016432780.1"
                     /locus_tag="F9278_RS23615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23630"
                     /product="proton-conducting transporter membrane subunit"
                     /protein_id="WP_226966889.1"
                     /transl_table=11
                     /translation="MTAATALFLTAPAAVPLAVAAGYALTGSVRHELPRGLPTVRRAQD
                     RRPQRAEKAAVVTAQGATSVSPRGEVADASPPGKSAVASSARARHPSDWAALASPTVIL
                     TCAALLAADRVDSGSVSAYSGLLRADALTAWMLLVVGAVAFIACASAPAHLAAERAAGS
                     ATAWTVWRYHMLVQTFLGAMCLAVVTGNLGVLWVAIEATTVVTAFLVGHRRTRTSVEAA
                     WKYVVLCSAGIALAFLGTVLLYYAARQAGISEAWALDWPTLVARADRLDPAVTRLGISL
                     VILGYGAKAGLVPLHAWLPDAHSQAPAPVSALMSGVLLAVAFAAILRYRVIADAALGPD
                     FTRVLLAGIALLTLTLAAGLLLAQRDYKRMLAYSSMEHMSLIALAAAIGSPLALSAALL
                     HIAGHGLAKATAFCASGRILQLRGTSKIGRVRGLLAQSPWLGALFGLAVVALLGFPPFS
                     LFASELGIARAGFAAGAGLSWVTAAALLLVLIAFAALATRTARMLLGPGEPSGESPSAL
                     WPLVLGLMACAALGIATGPLGDLLTQAAAVLERP"
     gene            1993..3471
                     /locus_tag="F9278_RS23620"
                     /old_locus_tag="F9278_23635"
     CDS             1993..3471
                     /EC_number="1.6.5.9"
                     /GO_function="GO:0008137 - NADH dehydrogenase (ubiquinone)
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065366.1"
                     /locus_tag="F9278_RS23620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23635"
                     /product="NADH-quinone oxidoreductase subunit C"
                     /protein_id="WP_152170107.1"
                     /transl_table=11
                     /translation="MRTVQDVPAAELPKRAEVLLRDGHRLALLAAHHDADAVRLVYLFV
                     SGPPDTRIELHVRLDPARPEVPSLAHLSFPAGRFEREMHDLHGIVPLDHPQPRRLVRHF
                     HWPKGWYPMHPDAGNPPAFGEQEGPYPFLEVTGDGVYEIPVGPVHAGIIEPGHFRFSVV
                     GETILKLKARLWFVHKGIEKLFQGRSIVAGLPLAERISGDTAVGHALAYCLAVEEATGT
                     TVPEQAQCARALLLELERLHNHVADLGMLCNDVGYGILNAHAQRVREHLLRLNHTVTGH
                     RLLRGGVVPGGSALHHLPGRNQMDAIGADIHEIVRLALGHSTVHDRFTGTAILPTQAAR
                     DIGCLGYVARASGLALDARIAHPFAPHGQPAKVPVHTSGDVLARFLVRAEEIDTSLTLI
                     GELTDCVATGAVHGPPADPGEGPRSGVALVEGWRGTIATRVELAADGTLKRVKPVDPSF
                     FNWPALPVALKDTIVPDFPLTNKSFNLSYAGNDL"
     gene            complement(3484..3879)
                     /locus_tag="F9278_RS23625"
                     /old_locus_tag="F9278_23640"
     CDS             complement(3484..3879)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065365.1"
                     /locus_tag="F9278_RS23625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23640"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_226966890.1"
                     /transl_table=11
                     /translation="MDRVEALALLAKAPFGRVVFSHQALPAIRPVNHLVEASGDIVIRT
                     HTGMALLGRAALSEVVAYEADDLDPVTRTGWSVVVTGTASPVSDPAELARYQAALTSWV
                     EADMEHVVRIRADLVTGYRLVRGGTGS"
     misc_feature    3966..3976
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    4022..4036
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.07"
                     /tool="antismash"
     gene            complement(4079..4243)
                     /locus_tag="F9278_RS46285"
     CDS             complement(4079..4243)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070681.1"
                     /locus_tag="F9278_RS46285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_193241605.1"
                     /transl_table=11
                     /translation="MNDETAEQPKGKKKAKDRDSWIERGVMIRAGFYIFGTHIVAGWVM
                     LLFYLGQHK"
     gene            complement(4300..4725)
                     /locus_tag="F9278_RS23630"
                     /old_locus_tag="F9278_23645"
     CDS             complement(4300..4725)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019065362.1"
                     /locus_tag="F9278_RS23630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23645"
                     /product="ATP-binding protein"
                     /protein_id="WP_226966891.1"
                     /transl_table=11
                     /translation="MAAVSPVPPSVARYCVSVEMAPEAVTRAREAVAEGLAEVGVVAGS
                     AFADAVLLVVSELVANVLRHAPRCPVADVELTVGAGQLIVGVADAEPRLPLLGPGEMGA
                     GLRLVAELAAEYEGGIGAKLTVNRDGKVVLVRFRMPS"
     misc_feature    4976..4992
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.63"
                     /tool="antismash"
     gene            complement(5103..5627)
                     /locus_tag="F9278_RS23635"
                     /old_locus_tag="F9278_23650"
     CDS             complement(5103..5627)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003948193.1"
                     /locus_tag="F9278_RS23635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23650"
                     /product="universal stress protein"
                     /protein_id="WP_152170109.1"
                     /transl_table=11
                     /translation="MSQWLPRRRHSGERCPRLPGAAPAPGAALPLRHDPFRHAIVVGYS
                     GSPSDERTLAYASGMAYRAGRGLVVVHVTHRLPSSSWWEGGEPMALLDLLEGSSESLAD
                     ALARTGQLTQVPWVAVHTRGDICHELEEISRWYAADAIVVGASRSITAKLFGRVGSRLA
                     RQPRHPVIVIP"
     gene            complement(5766..6185)
                     /locus_tag="F9278_RS23640"
                     /old_locus_tag="F9278_23655"
     CDS             complement(5766..6185)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070677.1"
                     /locus_tag="F9278_RS23640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23655"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_152170110.1"
                     /transl_table=11
                     /translation="MPSSTHPTAADAMLAPELQVSDHTSIDRALDVLRGSHTEFVLIRD
                     DTGRCAGIVTRDQLTAHGAKPWYAENTRVRDIAHDHSPFARPGMPAADVAADLRERSLA
                     ALPVVDDDGFALGIVTETRLQTVLAASAGGTAEQP"
     gene            complement(6217..6579)
                     /locus_tag="F9278_RS23645"
                     /old_locus_tag="F9278_23660"
     CDS             complement(6217..6579)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1058: ArsR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070676.1"
                     /locus_tag="F9278_RS23645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23660"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_152170111.1"
                     /transl_table=11
                     /translation="MSTPPLYQLKAEFLKTLGHPVRIRVLELLSSREYAVAEILPEVGV
                     EAAHLSQQLAILRRANLVATRREGSTVHYRLTTPEATNLLTAARSILSGVLAGQADLLA
                     DLQAAPAALPSRSRPA"
     gene            complement(6576..6887)
                     /locus_tag="F9278_RS23650"
                     /old_locus_tag="F9278_23665"
     CDS             complement(6576..6887)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070675.1"
                     /locus_tag="F9278_RS23650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23665"
                     /product="hypothetical protein"
                     /protein_id="WP_152170112.1"
                     /transl_table=11
                     /translation="MRWDSTEHDGVGVLHLFGFLGRQDTHRFDGAVDWVRSRSNGMLVL
                     DMSGLLGWSEEGEAAVVRAAQSPLAVCGLRDRPAPLLSGDTTGLIRIYPDLRSALATA"
     gene            7284..7481
                     /locus_tag="F9278_RS23660"
                     /old_locus_tag="F9278_23675"
     CDS             7284..7481
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (8-20). E-value:
                     0.00035. Score: 12.1. Matches aSDomain:
                     nrpspksdomains_F9278_RS23660_PKS_Docking_Nterm.1"
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F9278_RS23660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F9278_23675"
                     /product="hypothetical protein"
                     /protein_id="WP_152170114.1"
                     /transl_table=11
                     /translation="MSEGRESALRRLAAELRQARVEAEGRGDAWSAAVHTVDLEEVERV
                     GRELGVDLTGGADQAGAVRG"
     aSDomain        7308..7343
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F9278_RS23660_PKS_Docking_Nterm.
                     1"
                     /evalue="3.50E-04"
                     /label="F9278_RS23660_PKS_Docking_Nterm.1"
                     /locus_tag="F9278_RS23660"
                     /protein_end="20"
                     /protein_start="8"
                     /score="12.1"
                     /tool="antismash"
                     /translation="LRRLAAELRQAR"
     misc_feature    complement(7616..7630)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.93"
                     /tool="antismash"
     misc_feature    complement(7617..7632)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.28"
                     /tool="antismash"
     misc_feature    7815..7829
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.59"
                     /tool="antismash"
     gene            8042..8422
                     /locus_tag="F9278_RS23665"
                     /old_locus_tag="F9278_23680"
     CDS             8042..8422
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /locus_tag="F9278_RS23665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23680"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_152170115.1"
                     /transl_table=11
                     /translation="MAEIELSMDNDVQDCVVALVTGDMDYVSVSTFWPRVHALLDGDRR
                     LVLDLSGVDFFDSAGLNELLALNRRAAEGGGSLALANVPGMMRGLLSLTGTDAVLDVHA
                     TVGEAVAGRRKAEDADGVGPGR"
     gene            8765..9235
                     /locus_tag="F9278_RS23670"
                     /old_locus_tag="F9278_23685"
     CDS             8765..9235
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019070686.1"
                     /locus_tag="F9278_RS23670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23685"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_152170116.1"
                     /transl_table=11
                     /translation="MPVTLRHLDARLFPAWLERSRAEYANDLVTAGQTPEDAHRNADES
                     MARSFPSGTPGSGHVVFDVVDDAGETVGYLWIGPDTSDDAGAWWIWDIMIDADKRGRGF
                     GRRTMTLGEEYARAQGAHTLGLSVFGFNTGARGLYESLGYETTSVKMLKKLG"
     gene            complement(9239..9967)
                     /locus_tag="F9278_RS23675"
                     /old_locus_tag="F9278_23690"
     CDS             complement(9239..9967)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019632501.1"
                     /locus_tag="F9278_RS23675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23690"
                     /product="hypothetical protein"
                     /protein_id="WP_152170117.1"
                     /transl_table=11
                     /translation="MVYELIAICDACKQAVADGEGSFSVDMAEVDRCSTNTRAWEILET
                     AHEAPGVQSFDAASLMSYPEAACWHIDHAACDPSPNVNAYAIEVHRCRTWADLVLWTAY
                     LWRGTSFVVVSLRVRRFVCAADSCPRKTFVEQVPGLTRRFGRRIERLRSTLVPVGLALA
                     GRAGARMTDSFGAPVSRNTLLRLITSLPDSPTATPGVVGVDEYAQRKGQGSMIHRYTIW
                     RNRHADDRRLRAVVDRANVA"
     misc_feature    complement(9620..9622)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    9939..9954
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.86"
                     /tool="antismash"
     gene            complement(10001..10978)
                     /locus_tag="F9278_RS23680"
                     /old_locus_tag="F9278_23695"
     CDS             complement(10001..10978)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009315830.1"
                     /locus_tag="F9278_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23695"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_152170118.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.5e-26, bitscore:
                     91.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDLHDTRTAERAVHAVLAGTPIDAVAARLHSSPEHLAEAGKLYCA
                     AGRTALDARSSATDWRQVNIEFTDYPTAQHAFLAYLLPPLREACDVGAIGAWWFVRKFP
                     CWRLRVAPGPQPMGECASKPIHAALDSAVSWGVVKRWWPSQYESETVAFGGTDGMRIAH
                     ALFHADSVGVLDHLHGPAAEDSFPLDAKATSLIITTLFLRAAGQEWSEQGDVWARVEAK
                     RPLPDDVPPERVTAMTGTVRKLLTADTAPALTGGNPLDRLAEWADSIERGGQALGNAGR
                     EGGLGLGTRGILARHILFHFNRMGFTTRQQAIWSRAARETILGS"
     gene            complement(11008..12159)
                     /locus_tag="F9278_RS23685"
                     /old_locus_tag="F9278_23700"
     CDS             complement(11008..12159)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009326102.1"
                     /locus_tag="F9278_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23700"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_226966892.1"
                     /sec_met_domain="LANC_like (E-value: 3.2e-44, bitscore:
                     150.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTGARPVPEQDTAFRQSLAHGPLGIAMLHIEHARQSRGSWQAVH
                     RRLAAVGPLIDGDQAGLFLGAPAMAYVLHLTAADSNQYAGALNALDRIVTTHTRSRLDA
                     AHTRIDQGRPTSFAEYDLLRGLTGLGALLLRRTPDGPELKSVLEYLVRLTEPLPGPDGR
                     PRPGWWAGHSPVNLGTPTPDGHANAGLAHGITGPLALLALAHLRGTTVHGHQEAMLRIC
                     RWLDEIRVDDHRGTRWPRWTTDTTSSPMHPAAPSWCYGTPGLTRAQQLAALALGDTDRK
                     RMAERALLDCLADPLQLDQLTGRGLCHGIGGLIRVVQRIAQDADEPAAFTSFLPHLTER
                     FLAAETPTEAGFLEGTSGAALAFQSIETDEAPARDWDACLLLA"
     gene            complement(12156..15218)
                     /locus_tag="F9278_RS23690"
                     /old_locus_tag="F9278_23705"
     CDS             complement(12156..15218)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009319705.1"
                     /locus_tag="F9278_RS23690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23705"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_226966893.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3.4e-192,
                     bitscore: 639.0, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 8.7e-20,
                     bitscore: 70.2, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.2e-29, bitscore:
                     102.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGMYKAVDAILIRAAARPLAAQVPPWPDLDGSASGDVERWREWVG
                     KVWTDDATAAAIEVASPLLVEAVHGVLNGRNQRPRTVQRTVISLVRYLLRMQHRATPFG
                     LFAGPAPVRLGNQVQVQWGAGHRASARADAEWLTEIVTALEQNRDLLRRLPVIADPTCI
                     VRGTRIAVPHQPGKDGPAEVTLRRTPAAEAVLELARSPITVDDIVAKLHAGYPDTPTSV
                     IEDMVRGLVAHQILITSLRAPMTHDDALGHLVAELADLAELVAVSTEPQAATAGHLRQI
                     HQLLIRHDHSPADEQRALRTEATRRMTALTGVTERTLVVNLLPDCEVVLPAEVAREAEQ
                     ALHVMARISPFPAGPPAWQDYRARFLERYSMGALVPVRDLTDPDIGLGFPAGYRGSVLK
                     RPVQGSTRRDEHLLSLAQHAAANQVREVVLTEEDLAALAVDEATQVPAHVELCFSVLAT
                     SLDALQQGQFTLSIAGLSQAAGTTTGRFLAMLDSADRHRMTAAYAALPTLTADAERAQV
                     SSPPLRRRTQNVSRALAVTPHLLSLGEHNPAATLDLDDLAVTADSKRFYLASLSTGKLI
                     EPSVMNAVELTNATHPLVRFVTEVHRSHTAVLTPFAWGAAARLPFLPEVRTSRTILSPA
                     CWRLRLSDLGHNDNPGRLRRLTNWRCRYGVTRTVFLGSDDQRLRLDLDHPTHQHLLRME
                     LERTGTATLHEAPEDEAYGWLGHTHEITMPFASSLPPAVHHPRAIAVVRRDSGRLPGTS
                     PWAYLKIYCHPERVPEILTTHLPGLFQDWAGGEPLWWYTRYSDPDTHLRLRLRLPAPDA
                     FGTAAQHVGAWAAELRNTGLIRSIQWDTDEPETGRYGTGDTLAAAEHAFATDSAATIAQ
                     QTLGLLPHLQPAVTAASFTDIAATFTGSPAAGRRWLIEYLLKGQGEMPSRDLQALAIQL
                     TAPDSDFAALRALPGGERVVTAWANRRAALETYRTALADHGAEPTDVLPSLLHMHHNRA
                     AGIDPDNETICRRLARTAALSWSARTEGAPR"
     aSDomain        complement(14490..14753)
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F9278_RS23690_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.70E-22"
                     /identifier="RREFam001.1"
                     /label="F9278_RS23690"
                     /locus_tag="F9278_RS23690"
                     /protein_end="243"
                     /protein_start="155"
                     /score="70.2"
                     /tool="antismash"
                     /translation="VIADPTCIVRGTRIAVPHQPGKDGPAEVTLRRTPAAEAVLELARS
                     PITVDDIVAKLHAGYPDTPTSVIEDMVRGLVAHQILITSLRAP"
     gene            complement(15302..15493)
                     /locus_tag="F9278_RS23695"
                     /old_locus_tag="F9278_23710"
     CDS             complement(15302..15493)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04363.1"
                     /locus_tag="F9278_RS23695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23710"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_152170120.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 1.4e-14, bitscore:
                     52.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAQQGTTALKAATDFTAAADTDFDLNIETIASAPVVPGLLNDTGD
                     GCGATCQSACSNSTCIGG"
     CDS_motif       complement(15380..15493)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MAQQGTTALKAATDFTAAADTDFDLNIETIASAPVVPG"
                     /locus_tag="F9278_RS23695_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(15302..15379)
                     /prepeptide="core"
                     /locus_tag="F9278_RS23695_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class I"
                     /score="-5.70"
                     /molecular_weight="2240.4"
                     /monoisotopic_mass="2238.9"
                     /core_sequence="LLNDTGDGCGATCQSACSNSTCIGG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MAQQGTTALKAATDFTAAADTDFDLNIETIASAPVVPG"
                     /leader_location="[15379:15493](-)"
                     /alternative_weights="2258.4"
                     /alternative_weights="2276.4"
     gene            complement(15561..16808)
                     /gene="fxlM"
                     /locus_tag="F9278_RS23700"
                     /old_locus_tag="F9278_23715"
     CDS             complement(15561..16808)
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009329291.1"
                     /locus_tag="F9278_RS23700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23715"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_152170121.1"
                     /sec_met_domain="PCMT (E-value: 1.4e-38, bitscore: 131.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNVPDMITPDDGVPTSDQQLRDEMVRELIALDAARSPHVVAAFR
                     KVPRHLATPDDDMAAVYQAENAAITKKDADGVAISSVSAARIQAMQIEQADIRPGMRVL
                     EIGSGGVNAAYLAEIVGPEGLVITVDIEPDVTARAEKFLADTGYDQQVRVITADGEYGM
                     AEHAPYDRVIVTVQTADIPPAWTEQLVDGGRVVVPLRMRGMTRTVALVRHGDRLVSDSV
                     ELCGFVPMQGVGENRVRLVLLHDTEGEEVGLRLDGHPEPHADGLRAALRSPRVEAWSGV
                     TLAGDESSEHLDLWLTTALDNLPLLAATPAARKRGLVASASPLGVPTLVDADSFAYRTV
                     RRTDNPDRFELGAIGHGSQGQKAAERLVEEIRVWDREHRRDRAQIEVYPASTPDGQLPE
                     GRVVDRPHTRVLITWP"
     gene            complement(16839..17309)
                     /locus_tag="F9278_RS23705"
                     /old_locus_tag="F9278_23720"
     CDS             complement(16839..17309)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="F9278_RS23705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23720"
                     /product="ATP-binding protein"
                     /protein_id="WP_152170122.1"
                     /transl_table=11
                     /translation="MMTATGSRPSVGRILRAVATPLEPSPESVSRARRTVHDTLAAWGL
                     DNLADDMVLVASELVTNALQHTSGPIVMVLQQRDETVLIEVADVSSALPVQRRESADDE
                     SGRGLALVEAFSDDWGYRRRGNRRGKWVWCSWSLSPMATEHVDQPIPLEAAS"
     misc_feature    complement(16983..16985)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            17828..19153
                     /locus_tag="F9278_RS23710"
                     /old_locus_tag="F9278_23725"
     CDS             17828..19153
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003963503.1"
                     /locus_tag="F9278_RS23710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23725"
                     /product="DNA-binding protein"
                     /protein_id="WP_152170123.1"
                     /transl_table=11
                     /translation="MDERPRTLLKALVAQRHWRYSDFLAHFTRIAEKVVKKGTANPTIF
                     EAQFRRWTAGAIRTLPSPDACRVLEEMFGVSAAALFQGPPSPESPAPVFSLKDEIDMTA
                     RDASSEAGAAASASISDTTLDQLRDDVAELARRYHSFSAFEVLQTARRLREEAEQHRDR
                     TQVPAQQQHLLIIAGQACALLSAAAFDLGSLDGATRLARASALYGETARFTPLRAFAGG
                     ALAYIAYFSGRPAEAAQIAQRAQMLTGLGDVAHRRLAAIEARAHGHRGDAASAQQAIDV
                     SHREGRGETDDLHEGVAGEFGFPGERLAMSNASTCLLLGDGEQAEAAARTALELVTSKP
                     EALRSAHVVGGAAADLAAARLLSSDLDGAAEALEPVWTVPGEQRATGLLTRIARIRRAL
                     TDECFRRTPLADEIGDRLEHFSRLAAQHQLGAGAGAVAALEG"
     gene            complement(19160..20173)
                     /locus_tag="F9278_RS23715"
                     /old_locus_tag="F9278_23730"
     CDS             complement(19160..20173)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019436025.1"
                     /locus_tag="F9278_RS23715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23730"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_152170124.1"
                     /transl_table=11
                     /translation="MRILVLGGTWFLGRSIVDEALRRGWDVTTFNRGLSGRDVPEVRAV
                     HGDRTEVADLNRLASQGPWDAVIDTSSSELPPRDVRLAAQALRDTASRWVHVSTVSVYS
                     GWPHKTLTESSEVLDCPSDADESFGHTGSDGSPTKYGFQKAGGERAFGERAVFLRPGVI
                     LGPGEYVGRLPWWLNRAGRGGPVLAPAPADRLIQPVDVRDVAAFAVDQAAATTGGAFNV
                     AHPEGMGFGDFLLACLAITETDGHLVWVEPELLAEHGVRQWTELPLWRTHTGVWSVDAG
                     RAVEAGLRCRPLTETITDTWAWLRADGRPVDHPRWAEHGLAPEKEARILAALASAS"
     gene            complement(20312..22006)
                     /locus_tag="F9278_RS23720"
                     /old_locus_tag="F9278_23735"
     CDS             complement(20312..22006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014143638.1"
                     /locus_tag="F9278_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23735"
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="WP_152170125.1"
                     /transl_table=11
                     /translation="MVPDVSRGSRTIGLIHYLYRTSDIEAHVDPHLVAAYDPHLPDPGR
                     DAHATFSDLAADLDLWVDALGDNAPKKHVWHCPVRTAPGDRILSDEEWAIVARRVLNAT
                     GIVPDGDDQACRWIAVRHAPDHIHIVATLVRADRTRPRHHKDGTRAQAECRKIEKEFGL
                     RRLKEGDGTAAKRPTSAERHKAERLGQEAASRELLHEHVRRALAGAADEAEFFDRLAAE
                     GVRIKKRTAPSGDALGYKVAMVGDRNDTQEPIWFAGSTLAPDLSLPRIRKRFTIPTDTA
                     AQATALEPSGASAPARARYVAVQAADSALASMTSADDNTAAAQLIGIGEVLDALAQTSP
                     RSSRTELQAAARHFERASRSHIRAKNEEMYALRRAVGQIVHSGTALGRGPDGAATALIL
                     DVVILAVVAAARWHAARGHAQQAEAAQLTARHLRTAYQATAAGPLATLRAHGEHLPAPN
                     RRRHTATVHAALPHLADRLQAEPGWDGLTAVLDQAEHAGHNTAALLAKAAAQRELDSAD
                     SASDVLVWRLHHLGYVTAPPRRPKPNPAPTPVAAAIPQQEAARPRRR"
     gene            complement(22011..22469)
                     /locus_tag="F9278_RS23725"
                     /old_locus_tag="F9278_23740"
     CDS             complement(22011..22469)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF046164.1"
                     /locus_tag="F9278_RS23725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23740"
                     /product="plasmid mobilization protein"
                     /protein_id="WP_152170126.1"
                     /transl_table=11
                     /translation="MAEEARHQGAPGQGFVAEGGHEQRQEPSAKAGRGGRRRSRQPKQR
                     SERQTFRASTAEATEIQEAADAKGISKARFIAQAVHAEIHGRPRLDHDEALDVLEAARI
                     QLVRAGTNLNQIAKVLNSGGDAPHIARAADAVAGAATEIRTAARKLVS"
     gene            complement(22815..23633)
                     /locus_tag="F9278_RS23730"
                     /old_locus_tag="F9278_23745"
     CDS             complement(22815..23633)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326943.1"
                     /locus_tag="F9278_RS23730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_23745"
                     /product="DUF2637 domain-containing protein"
                     /protein_id="WP_226966895.1"
                     /transl_table=11
                     /translation="MPSPAPTAPAAVRGSLTIRVGIVLLATIGFALSYDALRQMAVASH
                     VRGLLTYLFPLVIDGFIAIGIVALLILRGAPLRSRLYVWALVGVATLTSIWANVVHAVG
                     LNEGTRLRLNNATVGALSGIAPLALAGAVHLYLVMNRHLGGDGAMADATLGTPPAESAM
                     PRQDRQIRHEETDDANTGVPAKANDVPMPEAKPASAMTVPRTDRRKRTVPDEELLTMAR
                     AIGADTGQVPRPALEKAVRAKGYSISKDGAQKAADIVRAELNAAKDAVAT"
     misc_feature    complement(24971..24987)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 19.61"
                     /tool="antismash"
ORIGIN
        1 cctcctcgcc tacgccgtcg cccgccccct ggtcgagctg gatccgaccc cggcgacccg
       61 cgcattgccg gtcggcctgg ccgtcgtgct gatcggcttc ttcgtcctgg tcacccggcg
      121 ccgcgcgctg gctcaggtgg tcggcttcct gctgctggac aacggcatca ccgcgaccgc
      181 cttcctggcc gcctccgggg tgccgctgat cgtcgaactc ggcgtctcct tcgacgtgct
      241 gctcgccgtc ctggtcctgc aggtactcac cgtgcgggtg cgggaggcgt tcggcaccac
      301 cgacatcgac gacctgcggg agctgcacga ctgatgaccg ccgccaccgc gctgttcctc
      361 accgcgcccg ccgccgtacc gctggccgtg gccgccgggt acgcgctcac cgggtccgtc
      421 aggcatgagc tgccccgcgg gttgccgacg gtccggcggg cgcaggaccg ccgtccacag
      481 cgtgcggaga aagccgctgt ggtcactgcc caaggcgcta cgagcgtctc gcccagggga
      541 gaagtggcag acgcctcccc acccgggaag tcggccgttg cctcctcggc gcgggcacgc
      601 cacccgtctg actgggccgc actggcctcc ccgacggtga tcctcacctg cgcggcactg
      661 ctggccgcgg atcgcgtcga cagcgggtcc gtgtccgcgt actccgggct gttgcgtgcc
      721 gacgcgctga cggcctggat gctgctggtc gtcggcgccg tcgccttcat cgcctgtgcc
      781 tcggcgcccg cccatctggc ggcggagcgg gccgccggga gcgcgacggc gtggaccgtg
      841 tggcgctacc acatgctggt ccagacgttc ctcggcgcga tgtgcctggc cgtggtcacc
      901 ggcaacctcg gcgtgctgtg ggtggcgatc gaggcgacca ccgtcgtcac ggcgttcctc
      961 gtcggccacc gccgcacccg cacctccgtc gaggccgcct ggaagtacgt ggtgctctgc
     1021 tcggccggca tcgcgctcgc cttcctgggc accgtgctcc tctactatgc ggcccggcag
     1081 gcaggcatct ccgaggcgtg ggcgctggac tggcccactc tggtggcccg tgcggaccgc
     1141 ctcgacccgg cggtcacccg gctcggcatc agcctggtga tcctcggata cggcgccaag
     1201 gcgggcctgg tgccgctgca cgcctggctg cccgacgcgc acagccaggc cccggccccg
     1261 gtctcggcgc tgatgtccgg ggtgctgctg gccgtggcct tcgccgcgat cctgcgctac
     1321 cgcgtcatcg ccgacgcggc cctcggcccg gacttcaccc gcgtcctgct ggccggcatc
     1381 gcgctgctca ccctcaccct cgccgccggc ctgctgttgg cccagcgcga ctacaagcgg
     1441 atgctggcct actccagcat ggagcacatg agcctgatcg ccctggccgc agcgatcggc
     1501 agcccgctcg ccctgtccgc cgcgctgctg cacatcgccg ggcacgggtt ggccaaggcc
     1561 accgcgttct gcgcctcggg ccggatcctg cagctacggg gcacgtcgaa gatcggacgc
     1621 gtccgcgggc tgctcgccca gtcaccctgg ctgggcgcgc tgttcgggct ggcagtggtg
     1681 gcgctgctgg gtttcccgcc gttcagcctc ttcgcctccg aactgggcat cgcccgcgcc
     1741 ggattcgccg ccggagccgg gctgagctgg gtcacggccg ccgccctcct gctggtcctg
     1801 atcgccttcg cggcgctggc cacccgcacc gcccggatgc tgctcggccc cggggagcca
     1861 tccggggaaa gcccctccgc cctgtggccg ctggttctcg gcctcatggc ctgcgccgcc
     1921 ctcggcatcg ccaccggccc gctgggcgac ctgctcaccc aggccgccgc cgtcctcgaa
     1981 aggccctgac cgatgcgcac cgtgcaggac gtccccgccg ccgaactgcc caagcgggcc
     2041 gaggtgctgc tgcgcgacgg acaccgtctc gccctgctcg ccgcccacca cgacgctgac
     2101 gccgtacgcc tcgtctacct cttcgtctcc gggccgcccg acacccgcat cgaactccac
     2161 gtgcgcctcg accctgcccg gcccgaggtg cccagcctgg cccatctctc cttccccgcc
     2221 ggccggttcg aacgcgagat gcacgacctg cacggcatcg tccccctcga ccacccccaa
     2281 ccccgccgcc tggtacgcca cttccactgg cccaagggct ggtacccgat gcaccccgac
     2341 gccggcaacc cgcccgcctt cggcgaacag gaagggccct accccttcct tgaggtcacg
     2401 ggcgacggcg tctacgagat ccccgtcggc ccggtgcacg ccgggatcat cgagcccggc
     2461 cacttccggt tctccgtcgt cggcgagacc atcctcaaac tcaaggcccg cctctggttc
     2521 gtgcacaagg gcatcgagaa gctcttccag ggccgcagta tcgtggccgg gctgccgctg
     2581 gccgagcgca tcagcggcga caccgccgtc ggccacgccc tcgcctactg cctcgccgtc
     2641 gaggaggcca ccggcacgac ggtgcccgaa caggcccagt gcgcccgcgc cctgctcctg
     2701 gaactcgaac gcctccacaa ccacgtcgcc gacctcggca tgctctgcaa cgacgtcggg
     2761 tacggcatcc tcaacgccca cgcccagcgg gtgcgcgaac acctcctgcg cctcaaccac
     2821 acggtgaccg ggcaccggct gctgcgcggc ggcgtcgtcc ccggcggcag cgccctgcac
     2881 cacctgcccg gccgcaacca gatggacgcc atcggcgccg acatccacga gatcgtccgg
     2941 ctggcgctcg gccactccac cgtccacgac cgcttcaccg gcaccgcgat cctgcctacc
     3001 caggccgccc gcgacatcgg ctgcctgggc tacgtcgccc gcgccagcgg cctcgccctg
     3061 gacgcccgca tcgcccaccc cttcgccccg cacgggcaac cggccaaagt ccccgtgcac
     3121 accagcggcg acgtcctggc ccgcttcctc gtccgcgccg aggagatcga cacctcactc
     3181 acgctgattg gggagctcac cgactgtgtc gccaccggcg ccgtccacgg gcccccagct
     3241 gaccccgggg agggcccccg cagcggcgtc gccctcgtcg aaggctggcg cggcaccatc
     3301 gccacccgcg tcgaactcgc cgccgacggc acactcaagc gggtcaagcc cgtcgacccg
     3361 tccttcttca actggcccgc cctgccggtc gccctgaagg acacgatcgt cccggacttc
     3421 ccgctgacca acaaaagctt caatctctcc tacgcgggca acgacctgtg accatgggac
     3481 cgttcaggag cctgtgccgc cgcgcaccag ccggtagccg gtcacgaggt cggccctgat
     3541 ccgcaccaca tgctccatgt ccgcctccac ccaggacgtg agcgcggcct ggtagcgggc
     3601 cagttcggcg ggatcggaga ccggggacgc ggtgccggtg accaccacac tccagccggt
     3661 ccgcgtgacg gggtcgaggt cgtccgcctc gtacgccacg acctccgaca gcgcggcacg
     3721 gccgagcagc gccatcccgg tgtgggtacg gatgacgatg tcgccgcttg cttcaacgag
     3781 gtggttgacg gggcgaatcg cgggcaacgc ctggtgggag aagaccacgc ggccgaacgg
     3841 cgccttggcc aacagggcca gcgcctctac ccggtccatc gggacaaggc ggctccgcga
     3901 tggttcaaca gccgccatgg ttcctctccg cacagggcca cgggcccgat gccctcacgc
     3961 cacagcgcca tgtcaccgtt ccccgttgac aacatggcca catccatacg gaggaacgca
     4021 agggccatcc ggccctccgt agctggacga ccggctctcg tggcggtcgg ttcctcggct
     4081 acttgtgctg gccgaggtag aagagcagca tcacccatcc ggcgacgatg tgtgtaccga
     4141 agatgtagaa gcccgcccgg atcatgaccc cgcgctcgat ccaactgtct cggtccttgg
     4201 ccttcttctt gcccttcggc tgctcggccg tctcgtcatt cacgttccgt ctcccttcat
     4261 cctgcgatct ccacggactt ccttcgacgg aaccgatggc tacgacggca tacggaaccg
     4321 gaccaggacg accttgccgt cacggttgac ggtcagtttc gcgccgatgc cgccctcgta
     4381 ctcggcggcc agctcggcca ccaaccgcag ccccgcaccc atctcaccgg gccccaggag
     4441 gggaagccgg ggttcggcgt ccgcgacgcc gacgatgagc tgtcccgctc cgaccgtgag
     4501 ctccacgtcg gcgaccggac agcgcggcgc atgccgcaac acgttcgcga ccagttcgct
     4561 gaccacgagc agcaccgcgt cggcgaacgc ggaacccgcc acgacgccga cctcggccag
     4621 gccctcggcc actgcctcac gggcccgtgt caccgcctcc ggcgccatct cgacagacac
     4681 gcagtaccgg gccaccgacg gcggaacggg gctgacagcc gccacgggcc agccccttcg
     4741 gcacggccgg aaccggtcgc ggcccctcac cgcgcccgct ccgccgcgcg caactcgccc
     4801 agcaggtcct gccgtcccag caggagaacg gacagcgcag tcggcatcct gctcactcct
     4861 cgcccgcccc gatgcccagc caccgaccgc tgcgcagtcg ctcagcgttg accggctcgc
     4921 cctgcgagcg cgagcgggtc cgtgacctcg cccccatggc cctgtactcc ctcggtgcta
     4981 gaaaattcgg caactgccta attgaagaac tctgcaattg tatgcctggt gaagctcccg
     5041 gtggggcccg ctcgccctaa gcggcgccac cgtctgccgg aggcggactg acgtgtctgt
     5101 cgctacggga tgacgatcac ggggtgccgc ggttgccggg cgaggcggct gccgacgcgg
     5161 ccgaagagct tggcggtgat gctgcggctg gcgccgacga cgatggcgtc ggccgcgtac
     5221 cacctgctga tctcttcgag ttcgtggcag atgtcgccgc gggtgtggac ggcgacccag
     5281 ggcacctgcg tgagctgccc ggtacgggcc agggcgtcgg ccagactctc gctgctgccc
     5341 tcgaggaggt cgaggagcgc catcggctca ccgccctccc accaactgga gctgggcagc
     5401 cggtgggtga cgtggacgac caccagaccc cggccggctc ggtacgccat accgctggcg
     5461 taggccagag tgcgctcgtc ggagggagat ccgctgtatc ccacgacgat ggcgtgccgg
     5521 aagggatcgt gccggagcgg aagcgccgcc ccgggagcgg gtgccgcacc gggcaggcgc
     5581 ggacaacgct cgccgctgtg gcgtctgcgc ggtagccact ggctcatggg gtcattcctg
     5641 gtgtaggagg cgggaactct cggtggctgg caggacgtct cggacgatcg cgcggaccgt
     5701 agggaaggga cgaatctcag cagccggtcg gggcgggcgg tggcgaatcg gtggccagga
     5761 ctcagtcagg gctgctcggc cgtgccgcct gccgatgccg cgagaaccgt ctgcaaccgg
     5821 gtctcggtga cgatgcccag ggcgaagccg tcgtcgtcga cgacgggcag ggccgccagc
     5881 gaacgctcgc gcaggtcggc ggccacgtcc gcggccggca tgccggggcg cgcgaacggg
     5941 ctgtggtcgt gcgcgatgtc acggacgcgg gtgttctcgg cgtaccaggg cttcgctccg
     6001 tgggcagtga gctgatcgcg ggtgacgatg ccggcgcatc gcccggtgtc gtcccggatg
     6061 aggacgaatt cggtgtgcga cccccggagt acgtcgaggg ccctgtcgat actggtgtgg
     6121 tcactgacct ggagttccgg cgcgagcatc gcatcggcgg cggtggggtg cgtagaggag
     6181 ggcatcgtcg gctccgggga caggagggcc gcagcgtcag gccgggcgag aacgagaggg
     6241 gagagcggcc ggcgccgcct ggagatctgc gaggaggtcg gcctggcccg ccaggacacc
     6301 actgaggatg ctgcgggccg cggtcagcag gttggtcgcc tcgggggtgg tgaggcggta
     6361 gtggacggtg gagccttccc tgcgcgtggc caccagattc gcgcggcgca ggatggccag
     6421 ctgctgcgac aggtgggcgg cttcgacgcc gacctcgggg agtatctcgg ccacggcgta
     6481 ctcgcgcgag ctgagcagtt ccagcacgcg gatgcgcacc gggtgaccga gggttttcaa
     6541 gaactcggcc ttgagctggt acagcggtgg tgtgctcacg ccgtggccag ggcggagcga
     6601 aggtcggggt agatccggat gagcccggtc gtgtcgccgc tcagcagcgg agcggggcgg
     6661 tcgcgcagtc cgcacacggc cagcgggctc tgcgcggcgc gcaccacggc ggcctcaccc
     6721 tcctcgctcc agccgagcag gccggacata tcgagcacga gcatgccgtt cgagcgggaa
     6781 cggacccagt ccacagcccc gtcgaagcgg tgcgtgtcct gacggcccag gaagccgaac
     6841 aggtgcagca cgcccacgcc gtcatgctcc gtggagtccc agcgcatgct caccaccgcc
     6901 ccagtcgctg ccagaagcgc agcgggccgg tccgcgccgg cttacggcgg gcgccggaca
     6961 cggactgaac gaggcgggaa ctcccgcacc gtgaacaccg tccctggccg tccagcgcgg
     7021 agggccggca cagcagtccg cacgccgagc agagcaggac gggagcactc gtgccgcgaa
     7081 tcggtgtgac gcgcatcgcg cctcctaggt aatccatcaa ttgccaatct tagcaactga
     7141 taacgtacgc agctagtggc tgccccttcc gggtcggcgc ggggcagcca cttatgcgcc
     7201 tgaagtaccg gtggagaagc gcgacttcag atgacttcgc cgtcgcgtgg gtcgggtgcg
     7261 tcggcaggca cgggaggcga tgaatgagtg aaggacgcga gtccgcgttg cgtcggctgg
     7321 cggcggagct gcggcaggcg cgtgtcgagg cggaagggcg gggggacgcg tggtcggccg
     7381 ccgtgcacac tgtggatctt gaggaggtcg agcgcgtggg gcgtgagctg ggcgtggacc
     7441 tgacgggcgg ggcggaccag gccggtgcgg tgcgaggttg atgagccgat cgcggccggg
     7501 gtccctgtcc ccgtcctgca tgggcgcgca ggcgaaggac ttggcggcgc cggactcaac
     7561 ctgcgcggga gctccggagg tacggaaggc gccgtcaacc gcatcaaggt ccggatgacc
     7621 atgatctcca ttgacgtccc cgaaccgggt cggcgccgta tccatctccg tgttcgggca
     7681 tttctcgccc ttgcatgagc gatgatcagt tcttgggcgc cgtggcgtgt gacgcagtcc
     7741 gctccgtagt ccccgttgtc gcgccggcag cggcagtatt tcggtcgttc cccgccgcgt
     7801 gggcgtggca tgagtgcatt tcgtgttcgt gatctggcgg tttcccgtag ttcgtcgcga
     7861 ggatgcccac cgtacgggcc gaggtggggc ggggcgccgc gggtgggccg gaagttcagg
     7921 agcgggcgcg aggagaagcg gtttcaacgg gcggagatgc ccgttcaggt cggtgcagtg
     7981 gtgtcgacgt ctcgtcctgt gatcgggcgt agtcggcacg gaccgtggat agggagcaga
     8041 cgtggccgag atcgaactga gcatggacaa cgacgtgcag gactgtgtcg tcgccctggt
     8101 tactggtgac atggactacg tgagcgtgtc caccttctgg ccccgcgtcc acgcgttgct
     8161 cgacggcgac cggcggttgg tgctggacct gtcgggggtg gacttcttcg actccgcggg
     8221 cctcaacgaa ctcctggcgc tgaaccgccg ggctgccgag gggggcggtt cgctggcgct
     8281 ggcgaacgtg cccggcatga tgcggggcct gttgtcgctg actggtacgg acgcggttct
     8341 ggacgtgcat gccaccgtcg gtgaggccgt ggccggacgg cggaaagctg aggatgcgga
     8401 cggcgtgggc cccggcagat gatcacaccc gggtcgtcag cgacccacac cgtcgctgcg
     8461 tcgaccgagc agccgcgcgt acatcgggct gacaggagcg tttctgcgcc tggtgcgcgt
     8521 cgttgggccg ggcatggatc caatgggatc cagacgagga cggcgtactg ctggctctcc
     8581 acggtccagc cggaccgctg agcgtgtgcc ggctggtggt caacgctccg tcgccggacc
     8641 cgttggtccg ctcccgctgc cggacggaac ggatcgaggg tggtgcggcc ggcggctgcg
     8701 cgagccgtag cggttgggcg ggggtgatac cgctccgacg tcggcggtgt gggaggctga
     8761 ttcgatgcct gtaaccctcc gccacttgga tgcccgactc ttccctgcct ggcttgagcg
     8821 cagtcgagcc gagtacgcca atgatctcgt cactgcgggg caaacgcccg aggatgccca
     8881 ccggaatgcg gacgaaagca tggcccgctc ttttccctcc ggcacaccgg gctcggggca
     8941 cgtggtcttc gacgtagtcg atgacgccgg ggaaaccgtc ggttacctct ggattggacc
     9001 agacaccagc gacgacgccg gcgcctggtg gatctgggac atcatgatcg acgccgacaa
     9061 gcgcggtcgg ggcttcgggc gaaggaccat gaccctcggt gaggaatacg cccgggcaca
     9121 aggcgctcat acccttggtc tcagcgtctt tggcttcaac acgggtgcgc gcggccttta
     9181 cgagtcgctt ggctacgaga cgacctcggt caagatgctc aagaaactcg gctgaggttc
     9241 aggcaacgtt cgctctgtcg acgacggcgc gtaggcgccg gtcgtcggcg tggcggtttc
     9301 gccagatggt gtagcggtgg atcatgctgc cctgtccctt gcgctgggcg tactcgtcca
     9361 cgccaaccac accgggtgtc gcggtgggcg agtcgggcag cgaggtgatc agcctcagca
     9421 gggtgttccg gctgaccggc gctccgaagg agtccgtcat ccgggcgcca gcccggcccg
     9481 caagcgcaag accgaccggg accaaagtcg agcgcagccg ctcgatccgc cgaccgaacc
     9541 gacgggtgag cccgggcacc tgctcgacga aggtcttgcg cggacaggag tccgctgcgc
     9601 agacgaaccg acgcacccgt aacgacacca cgacgaacga ggtccctctc catagatagg
     9661 cggtccacag gacgaggtcc gcccaggttc ggcatcggtg cacctcgatg gcgtacgcgt
     9721 tcacattggg cgacgggtcg cacgcggcgt ggtctatatg ccagcaggca gcctcggggt
     9781 acgacatcag gctcgccgcg tcgaaggact gaactcccgg tgcctcatga gcggtttcga
     9841 ggatctccca cgcacgggtg ttggtggagc accggtcgac ttccgccatg tccaccgaga
     9901 agctgccttc gccgtcggct actgcttgct tgcacgcgtc gcagatggcg atcagttcat
     9961 acaccacggt cggtccttga ggaggtctcg tcgtgacggg ctagcttccg aggatggtct
    10021 ctcgtgccgc tcgtgaccag atggcctgct gacgcgtggt gaagcccatg cggttgaagt
    10081 ggaacaggat gtggcgggcg aggatgccgc gggtgccgag gccgagccct ccttcgcggc
    10141 ccgcgttccc gagggcctgg ccgccgcgct cgatcgagtc ggcccactcg gcgaggcggt
    10201 ccagggggtt gcctccggtg agggcaggcg cggtgtcggc cgtcaggagc ttgcgcaccg
    10261 tgccggtcat ggcggtcacc cgctccggcg gaacatcgtc ggggagaggg cgcttggctt
    10321 caacgcgtgc ccatacgtcg ccctgctcgc tccattcctg tccggcggcg cgcaggaaca
    10381 gggtggtgat gatcagcgag gtggccttgg cgtcgagcgg gaagctgtct tctgctgccg
    10441 gaccatgcag gtggtcgaga actcccacgc tgtccgcatg gaacaaggcg tgggcgatcc
    10501 tcatcccgtc agtgccgccg aaggccaccg tctcggactc gtactgcgac ggccaccagc
    10561 gtttcaccac gccccacgag actgcgctgt cgagagccgc atggatgggc ttcgatgcgc
    10621 actcgcccat cggctgcggg ccgggagcga cgcggagtcg ccagcagggg aacttgcgga
    10681 cgaaccacca ggcgccgatg gccccgacgt cgcaggcttc tcgtagaggc ggcagcaggt
    10741 aggcgaggaa ggcgtgttgg gcggtcgggt agtcggtgaa ctcgatgttc acctgccgcc
    10801 agtcggtggc ggacgatcgt gcgtcgagtg ctgtccgtcc agcggcgcag tacagcttgc
    10861 cggcttcggc caggtgttcc ggtgaggagt gcagccgggc ggcgaccgcg tcgatcggtg
    10921 tgccggccaa gacggcgtgg acggctcgtt ctgctgttct ggtgtcgtgc aggtccacgt
    10981 cttcctcctt tcggggcctc tgtcatgtca agcgaggagc aggcaggcat cccagtctct
    11041 ggccggtgcc tcgtcggttt cgatgctctg gaaggcgagt gcggctccgg acgtgccttc
    11101 gaggaacccg gcttccgtcg gtgtctcggc ggcgaggaag cgttcggtga gatgcggcag
    11161 gaagctggtg aaagcggcgg gctcgtcggc gtcctgggcg atgcgctgaa ctacccgtat
    11221 gaggccgccg atgccgtggc acaggccccg accggtgagt tggtcgagtt ggagagggtc
    11281 ggccaggcag tccaggagcg ctcgttcggc catgcgtttg cggtcggtgt cgccgagggc
    11341 gagggcggcg agttgctggg cgcgggtgag gccgggagtg ccgtagcacc aggatggtgc
    11401 ggccgggtgc atggggctcg atgtggtgtc ggtggtccag cgcggccatc gggtgcctcg
    11461 gtggtcgtcg acgcgtatct cgtccagcca gcggcagatg cgcagcatcg cctcctggtg
    11521 gccgtgcaca gtggtgccgc gcaggtgggc gagtgcgagg agggccaggg gcccggtgat
    11581 gccgtgggcc aggccggcat tggcgtggcc gtcgggggtg ggtgtgccga ggttgacggg
    11641 gctgtgccct gcccaccagc cgggtcgtgg gcgtccgtcg gggccgggga gcggctcggt
    11701 caggcgcacg aggtattcca ggacgctttt gagttctggg ccgtcggggg tgcggcgcag
    11761 gaggagggct ccgaggccgg tgaggccgcg cagtaggtcg tactcggcga agctggtggg
    11821 tcggccctga tcgatacggg tgtgggcggc gtccaggcgg cttcgggtgt gcgtggtcac
    11881 gatgcggtcg agggcgttga gggcgccggc gtattggttg ctgtcggcgg cggtcaggtg
    11941 caggacgtat gccattgcgg gtgcgccgag gaagaggccc gcttggtcgc cgtcgatcag
    12001 tgggccgacg gcggcgagtc gacggtggac ggcctgccac gatccacggc tttggcgggc
    12061 gtgttcgatg tggagcatgg cgatgccgag ggggccgtgg gcgagggact gccggaaggc
    12121 ggtgtcctgc tcggggacgg gtctggcgcc ggtggtcacc gtggtgctcc ttcggtgcgg
    12181 gcgctccagg acagggcggc ggtgcgggcc aggcggcggc agatggtctc gttgtcggga
    12241 tcgatgccgg ctgcccggtt gtggtgcatg tgaagcagag acggcagtac gtcggtgggt
    12301 tcggcgccgt ggtcggcgag ggctgtgcgg tacgtctcca gtgcggcgcg gcgattggcc
    12361 caggcggtga cgacgcgttc gccgcctggc agggctcgta gcgcggcgaa gtcgctgtcc
    12421 ggggcggtca gttgtatggc cagtgcttgg agatcacgcg aaggcatctc gccttgcccc
    12481 ttgagcaggt actcgatcag ccagcggcgc ccggccgccg ggctgccggt gaacgtggcg
    12541 gcgatgtccg tgaagctggc ggcggtgacg gccggctgca ggtggggaag taggccgagc
    12601 gtttgttggg cgatggtggc ggcggagtcg gtggcgaagg cgtgctcggc ggcggccagg
    12661 gtgtcgccgg tgccgtagcg gccggtctca ggttcgtcgg tgtcccactg aatgctgcgg
    12721 atcagtccgg tgttgcggag ttccgccgcc caggctccga cgtgctgcgc ggcggtgccg
    12781 aaggcatcgg gggccggcag tcggaggcgt agacgcaggt gggtgtccgg atcgctgtag
    12841 cgcgtgtacc accacaacgg ctcgccgcct gcccagtcct ggaacagacc gggcaggtgc
    12901 gtggtcagga tctccgggac gcgttcgggg tggcagtaga tcttcaggta cgcccatgga
    12961 gaggtgcccg gcaggcgccc gctgtcgcgc cgtacgaccg caatcgctcg ggggtggtgg
    13021 actgcgggtg ggaggctgga ggcgaacggc atggtgattt cgtgggtgtg gccgagccag
    13081 ccgtatgcct cgtcctcggg ggcttcgtgc agtgtcgcgg tgccggtgcg ctccagctcc
    13141 atgcgcagga ggtgttggtg ggtggggtgg tcgaggtcga ggcggaggcg ctggtcgtcg
    13201 gagccgagga agacggtgcg ggttacgccg tagcggcagc gccagttggt gaggcggcgt
    13261 agccggccgg gattgtcgtt gtggccgagg tcgctcagtc gcaggcgcca gcaggcgggc
    13321 gagaggatgg tgcggctggt gcggacttcg ggcaggaagg gcagtcgggc ggcggctccc
    13381 caggcgaagg gggtcagcac tgctgtgtga gagcggtgca cctcggtgac gaagcggacc
    13441 aacggatggg tggcgttggt gagttcgacg gcgttcatca ccgacggctc gatgagtttg
    13501 ccggtggaca gcgaagccag gtagaagcgc ttcgagtccg cggtcaccgc gaggtcgtcc
    13561 aggtcgagcg tggcggcggg gttgtgttcg cccagcgaca gcaggtgtgg cgtgacggcg
    13621 agggcgcggc tgacgttctg ggtacggcgg cgcagcggcg ggctggagac ctgcgctcgc
    13681 tccgcgtcgg cggtgagcgt gggcagggcc gcgtacgcgg ccgtcatgcg gtggcggtcg
    13741 gctgaatcca gcatggccag gaaccgtcct gtcgtcgtgc ccgccgcctg agacaggccc
    13801 gcgatgctca gcgtgaactg cccctgttgc aaggcgtcca gggaggtggc gagcacggag
    13861 aagcacagct cgacatgggc agggacctga gtggcttcgt cgacggcgag cgcggcaagg
    13921 tcctcttccg tcaggaccac ctcgcgtacc tggttcgccg ccgcgtgttg ggcgagggac
    13981 aggaggtgtt cgtcccggcg ggttgagccc tggacgggtc gcttgaggac ggagccgcgg
    14041 taacccgccg gaaaaccgag gccgatgtca ggatccgtga ggtcgcggac cggaacgagg
    14101 gcgcccatgc tgtagcgctc caggaaacgg gcgcggtagt cctgccaggc cgggggccca
    14161 gccgggaacg gcgagatacg ggccatgacg tgaagggcct gttctgcttc tcgggcgacc
    14221 tcggcgggca ggacgacttc gcagtcgggc agcagattca ccaccagggt ccgctcggtg
    14281 acgccggtca gggctgtcat gcgccgggtg gcctcggtgc gcagcgcccg ctgttcgtcg
    14341 gccggggaat ggtcgtgccg gatcagaagc tgatggatct gccggaggtg cccagccgtt
    14401 gctgcctggg gctcggtgct gacggctacc agttcggcca ggtctgccag ttcggccacc
    14461 aggtgcccga gggcgtcgtc atgggtcatg ggcgcccgca ggctggtgat gaggatctgg
    14521 tgtgcgacga ggccacgcac catgtcctcg atcaccgacg tgggcgtgtc gggatagccg
    14581 gcgtgcagtt tggcgacgat gtcgtcgacc gtgatcggcg aacgggccag ttcaaggact
    14641 gcctcggcag cgggcgtgcg gcgcagggtg acctcggccg ggccgtcctt gcccggctga
    14701 tgcggtacgg cgatccgggt gccccggacg atgcaggtgg gatcggcgat cacgggcagg
    14761 cgtcgcagca gatcgcggtt ctgctccagg gcggtgacga tctcggtgag ccactcggcg
    14821 tccgctcggg cggaagcccg gtgtccggcg ccccattgga cctgcacctg gttcccgagg
    14881 cgtacgggcg cggggccggc gaacaggccg aagggggtgg cacggtgctg catccgcagc
    14941 aggtagcgca ccagggagat gaccgtgcgc tggacggttc ggggccgctg gttacggccg
    15001 ttgagcaccc cgtgcacggc ctcgaccaga agagggctgg cgacctcgat ggcagccgcc
    15061 gtggcatcgt ccgtccagac cttgccgacc cactcccgcc agcgctccac atcgccggag
    15121 gcgctgccgt ccaggtcagg ccagggaggc acctgggccg ccagaggccg ggcggctgct
    15181 ctgatcagaa tcgcgtcaac ggccttgtac atccccatcc catccctgtg gctccttcgt
    15241 ccgtcgtcct gggcggtgcg gggccgggcc gaagtcctcg gcccggcccc gcaccggttg
    15301 gtcagcctcc gatgcaggtg ctgttggagc aggcggactg gcaggtggcc ccgcagccgt
    15361 cgccggtgtc gttcagaaga cccggcacga ccggggcgga cgcgatggtc tcgatgttga
    15421 ggtcgaagtc cgtgtcggcg gcggccgtga agtccgtggc ggccttgagc gcggtggtgc
    15481 cctgctgtgc catctcgaat tcctcctgta gggctgggtg ggatgtgcct tgctggcctg
    15541 gccggtgggc gctgtcggcg ctacggccag gtgatcagga cccgcgtgtg gggccggtcg
    15601 acgacccggc cctcggggag ctgcccgtcc ggcgtggacg ccgggtagac ctcgatctgt
    15661 gcccggtcgc ggcggtgctc gcggtcccag acccggatct cctccaccag tcgctcggcg
    15721 gccttctggc cctgcgagcc gtggccgatg gcgccgagct cgaatcggtc cgggttgtcg
    15781 gtacgacgca cggtgcggta ggcgaagctg tccgcgtcga cgagtgtggg cacgccgagc
    15841 ggcgaggcgg aggcgaccag gccgcgtttg cgggcagccg gtgtcgcggc caggagcggc
    15901 aggttgtcca gcgcggttgt cagccacagg tccaggtgct cgctggactc gtcaccggcg
    15961 agcgtcaccc cggaccaggc ttcgacacga gggctgcgca gggcggctcg cagcccgtcg
    16021 gcatggggct cggggtggcc gtccagccgc agcccgacct cttcgccctc ggtgtcgtgc
    16081 aggaggacca ggcggacccg gttctcgccg acgccctgca tgggcacgaa accgcacagc
    16141 tcgacgctgt cgctcaccag ccggtcgccg tggcggacga gagcgacggt gcgggtcata
    16201 ccgcgcatcc gcaggggcac gacgacacgg ccgccgtcga cgagttgttc ggtccaggcc
    16261 ggcgggatgt cggcggtctg gacggtgacg atgacgcggt cgtacggggc atgctcggcc
    16321 atgccgtact cgccgtcggc ggtgatgacg cgcacctgct ggtcgtagcc ggtgtcggcg
    16381 aggaacttct cggcgcgtgc ggtgacgtcg ggttcgatgt ccacggtgat gacaaggccc
    16441 tcggggccga cgatctcggc gaggtaggcg gcgttgacac cgccggagcc gatctccagg
    16501 acccgcatgc cgggccggat gtcggcctgt tcgatctgca tggcctggat gcgggcggcg
    16561 gacaccgagc tgatggccac gccgtcggcg tccttcttcg tgatcgcggc attctccgcc
    16621 tggtacaccg ccgccatgtc atcgtcgggg gtggccagat gacgagggac cttgcggaac
    16681 gcggccacta cgtgcgggct ccgggctgca tcgagcgcga tcagttcccg gaccatctcg
    16741 tcgcgcaact gctggtcgga tgtcgggact ccgtcgtcag gggtgatcat gtcggggacg
    16801 ttgttcacgg gctctctctt tctcggcggt ggaggttgtc acgacgcagc ctccaggggg
    16861 atgggctggt cgacgtgctc ggtggccatg ggactcagtg accagctgca ccacacccac
    16921 ttaccgcgac ggttcccccg cctgcggtat ccccagtcgt ccgagaacgc ctccaccagc
    16981 gctaacccgc ggccggactc gtcgtcggcc gactcgcggc gttgcaccgg aagagcggaa
    17041 gagacatcgg cgacctcgat gaggaccgtc tcgtcgcgct gctgcaacac catcacgatc
    17101 ggccctgagg tgtgctgcag ggcattggtc acgagttctg acgcgacgag caccatgtcg
    17161 tccgccaggt tgtccaggcc ccatgcggcc agcgtgtcgt gcacggtcct gcgcgccctg
    17221 gacacggatt ccggactggg ctccagaggc gtcgcgaccg cgcgcaggat gcggccgacc
    17281 gacggccgcg atccggtggc cgtcatcatt cccacctgcg caatgcgtcc tggactcgcc
    17341 gtacgaccct cgtgctgttg ctgaaacggc tgaccgaggc gcaatcggcg ccctcaccgg
    17401 ccggagtcgc ccacggctgc acggccagag tggtgggaca ggcccggcca cccggacgta
    17461 ggggaagcgg ccgtctgtcc tggagggcca gtggagggct ttcctgcatc gcggcgaggc
    17521 tcctttggaa gggacggaca agaccgagcg ggatctcaac caccgtgtac gttgccggtg
    17581 atagctcctc gcactcggtg acggcgacca gagtgggcct gatgtggatc tcaccggcat
    17641 ggcccagcag atagcgtccg gcgctcttcc gggtgacaaa cgtcgcgcgc gggtagcgtc
    17701 gaagtgtcgt ctgagccaag ggcgttgcat tcggagcagg tgacgggatc ccctgcttgc
    17761 gagggagccg caggcccagg gccgacggcg gatggtcagt ggtcttcttg gccgagaggg
    17821 gccgacgatg gatgaacgtc ccaggacgct gctcaaggct ctggtggccc aacgccactg
    17881 gcgttacagc gacttcttgg cccacttcac gcgcatcgcc gagaaggtcg tcaagaaggg
    17941 caccgcgaac ccgacgatct tcgaggcgca gttccgccga tggaccgcgg gagccatccg
    18001 gaccctgccg agcccggacg cgtgccgggt gctggaggag atgttcggcg tcagtgccgc
    18061 cgccctgttc caggggccgc cctcgcccga gtcacccgca cccgtattca gcctgaaaga
    18121 cgagatcgac atgaccgcac gcgacgcatc cagcgaggcc ggcgccgccg cctccgcgtc
    18181 catctccgac accactctcg accagttgcg agacgacgtc gccgaactcg cccgccgcta
    18241 ccactccttc tcggcgttcg aggtcctcca gaccgcgcgc aggctgaggg aggaagccga
    18301 acagcaccgc gaccgcaccc aggtgcctgc ccagcaacag cacctgctga tcatcgcggg
    18361 ccaagcctgc gcactgctgt ccgcggcggc cttcgacctc ggttccctcg acggcgccac
    18421 ccgccttgcc cgcgcctccg ccctgtacgg ggagaccgcc cgcttcacgc cgctacgggc
    18481 ctttgccgga ggcgctctcg cctacatcgc ctacttctcc ggccgccccg ccgaggcagc
    18541 ccagatcgcg caacgcgcgc agatgctcac cggcctcggc gacgtcgcgc accgccgcct
    18601 ggcagccatc gaggcacgcg cgcacggcca ccgaggcgac gccgcctccg cccagcaggc
    18661 cattgacgtc tcccatcggg agggacgcgg tgagaccgac gacctgcacg aaggcgtggc
    18721 cggcgaattc ggcttccccg gcgagcggtt ggccatgtcc aacgcctcga cctgcctgct
    18781 cctcggtgac ggcgaacagg ccgaggccgc agcccgcacc gccctggagc tggtaaccag
    18841 caagcccgag gcactgcgct ccgcacacgt cgtgggcggc gccgccgcgg acctggccgc
    18901 cgcgcggctg ctgagcagcg atctcgatgg agccgccgaa gccctcgaac cagtctggac
    18961 cgtgccaggt gagcaacgcg ccaccggcct gctgacccgc attgcgcgca tccgccgggc
    19021 cctgaccgac gaatgcttcc gccgaacgcc cctcgccgac gagatcggtg atcgcctgga
    19081 gcacttcagc cgactcgccg cccagcacca gcttggtgcg ggcgccggag cggtggccgc
    19141 cctggaggga tgagggaact caggaagcgg aggccagggc agcgaggatc ctggcctcct
    19201 tctcgggggc gagcccgtgc tccgcccagc gggggtgatc cacagggcga ccgtccgccc
    19261 gcagccacgc ccaggtgtcc gtgatcgtct cggtgagcgg acggcaccgc agaccggcct
    19321 ccaccgcacg gccggcatcc accgaccaca cccctgtgtg agtacgccac aggggcagtt
    19381 cggtccactg ccgcactccg tgctcggcga gcaactccgg ctccacccag accaggtggc
    19441 cgtccgtctc ggtgatggcg aggcacgcga gcaggaagtc cccgaagccc atcccctcag
    19501 ggtgggccac gttgaaggca ccgccggtgg tcgcagctgc ctggtccacg gcgaaggccg
    19561 cgacatcgcg cacgtcgacc ggctggatga gccggtcggc cggagccggc gccagcacag
    19621 gtccgccccg gccggcccgg ttcagccacc acggcagccg acccacgtac tcacccggcc
    19681 caagaatgac cccgggccgc agaaacaccg cccgctcacc gaacgcccgc tccccgccgg
    19741 ccttctgaaa cccgtacttg gtgggcgaac cgtccgagcc cgtgtggccg aaggactcgt
    19801 ccgcgtcgga cgggcagtcc agcacctcgg acgactcggt cagggtcttg tgcggccacc
    19861 ccgaatacac cgacacggtg gagacgtgca cccaccggga cgccgtatca cgcagcgcct
    19921 gtgcggccag ccgcacgtca cgcggcggca gctcggaact cgacgtgtcg atcacggcat
    19981 cccaaggacc ctgggaagca agccggttga ggtccgctac ttcggtacgg tcgccgtgga
    20041 ccgcgcgcac ctcgggcaca tcccgcccgg acagaccgcg gttgaacgtc gtcacgtccc
    20101 aaccgcggcg tagcgcctcg tccacgatgc tcctgcccag gaaccacgta ccgcccaaga
    20161 ccagaatcct catgcccaga atcctgccct tcccgaggac ccaggagaag agaccccagc
    20221 ccagcggtgg ggaacagagc cttgtttcaa gggcgtcagc gtggcccgcg ccagctgatc
    20281 accgtggtcg cgggcagggc cacggtgacg gtcaccgtcg gcgtggtcgc gccgcttcct
    20341 gctgggggat ggctgccgcg acgggcgtcg gagcggggtt cggctttggg cggcgtggcg
    20401 gcgcggtgac gtatccgagg tggtgcagcc gccagacgag gacgtcgctg gccgagtcgg
    20461 cgctgtcgag ttcgcgttgg gcggctgctt tggcaagcag ggcggccgtg ttgtggccag
    20521 catgttcggc ctggtcgagg acggctgtca gtccgtccca gccgggctcg gcctggaggc
    20581 ggtcggcgag gtggggtagg gcggcgtgga ccgtggcggt gtggcgtcgt cggttcgggg
    20641 cgggcaggtg ttcgccgtgg gcgcgcagtg tggccagtgg gccggcagcg gtggcctggt
    20701 aggcggtacg caggtggcgg gcggtgagct gtgcggcctc ggcctgctgg gcgtggccgc
    20761 gggcggcgtg ccagcgggcg gcagcgacaa cggccaggat cacgacatcg aggatcaggg
    20821 cggtggcggc gccgtccggg ccgcggccga gggctgtgcc ggagtggacg atctggccga
    20881 ctgcacggcg cagggcgtac atctcctcgt tcttggcgcg gatgtgggag cgactggcac
    20941 gctcgaaatg ccgtgcggct gcttgcagtt cggtgcggct ggatcggggt gaggtctggg
    21001 cgagagcgtc gaggacctcg ccgatgccga tcagctgggc cgccgctgtg ttgtcgtccg
    21061 cggacgtcat cgacgcgagg gcggagtcgg cggcctggac agcgacgtag cgggcgcggg
    21121 ctggtgccga ggcgccgctc ggctccaggg ccgtggcctg cgcggccgtg tccgtgggga
    21181 tggtgaaccg tttccggatg cggggcaggg agaggtcggg ggcgagggtg gatccggcga
    21241 accagatggg ctcctgggtg tcgttgcggt cgccgaccat ggcgaccttg tagccgagcg
    21301 catcaccgga gggtgcggtg cgcttcttta tgcgtacgcc ttccgcggcg agccggtcga
    21361 agaactccgc ctcgtcggcg gcgccggcca gggcgcggcg gacgtgctcg tgcaacagct
    21421 cacgggaggc ggcttcctga ccgaggcgtt cggccttgtg gcgctcggcg ctggtggggc
    21481 gcttggcggc ggtgccgtcg ccttccttga ggcggcggag cccgaactcc ttctcgatct
    21541 tgcggcattc ggcctgggcg cgggtgccgt ccttgtggtg gcggggtcgg gtgcggtcgg
    21601 cgcggacgag ggtggcgacg atgtggatgt ggtcgggagc gtggcgcaca gcgatccagc
    21661 ggcaggcttg gtcgtcgccg tcggggacga tgccggtggc attcaggacc cggcgggcga
    21721 cgatcgccca ttcctcgtcg gacaggatcc ggtcgccggg ggctgtacgg acggggcagt
    21781 gccacacatg cttcttcggc gcgttgtcgc cgagggcgtc gacccacagg tcgaggtcgg
    21841 cggccaggtc gctgaaggtg gcgtgcgcat cgcggccggg gtcgggcagg tgggggtcgt
    21901 aggcggcgac gaggtggggg tcgacgtggg cctcgatgtc gctggtgcgg tagaggtagt
    21961 ggatcagccc gatggtgcgg gagccgcggg agacgtcggg gaccaaggtc tcagctcacc
    22021 agcttccgtg cggcggtgcg gatctcggtg gcggcacccg cgacggcgtc ggcggcgcgg
    22081 gcgatgtggg gtgcgtcgcc accggagttg aggaccttgg ctatctggtt gaggttggtg
    22141 ccggcgcgca ccagctggat gcgggcggct tcgaggacgt cgagggcctc gtcgtggtcc
    22201 aggcgagggc gcccgtggat ttcggcgtgg acggcctggg cgatgaagcg ggccttggag
    22261 atgcccttgg cgtcggcggc ctcctggatc tcggtggcct cggcggtgct ggcgcggaag
    22321 gtctggcgct cggagcgctg cttgggctgc cgggagcggc gacgtcctcc ccgcccggcc
    22381 ttggccgacg gctcctgccg ctgttcgtgg ccgccctcgg ccacgaaccc ctgacccggc
    22441 gccccctggt gacgggcctc ctccgccacc cccgaggcgg aggcaagcgc actggaccgg
    22501 ccatgggacg gtccagtgct acagcttgct ccgtctgggg caggggtggt ggtcgtctcc
    22561 tgctggggtg tggggagttg gtggtgctca ccggacattg gtttcttctc catggagtcg
    22621 tgcgggatgc ggaccgtaag cgcgggcgtg gacccgagga ccgcgagggg cagtcacagg
    22681 gcggggcttg ggagtcggcg tggtgcaggt gaagagctga agtgctgggg cgcgggctgg
    22741 cagcgacgct caggaggctg tgcctggcgt tggcggaacg tgatccgcca acgccctgcg
    22801 ttctgccgta gcgctcatgt ggcgacggcg tccttggcgg cattcagttc cgccctgacg
    22861 atgtcggcgg ccttctgggc gccgtccttg ctgatcgagt agcccttggc ccggaccgcc
    22921 ttctccaagg cagggcgggg gacttggccg gtatcggccc ctatggcgcg ggccatggtc
    22981 agcagctcct cgtcgggtac ggtgcgtttg cgccggtccg tcctgggcac cgtcatggcg
    23041 ctggcgggct tcgcctcggg catgggcacg tcgttcgcct tggcgggcac cccggtgttg
    23101 gcgtcgtccg tctcctcgtg gcggatctgg cggtcctgcc ttggcatggc ggattcggcg
    23161 ggcggcgtgc cgagggtcgc gtccgccatg gcgccgtcgc cgccgaggtg gcggttcatc
    23221 acgaggtaga ggtggacggc gccggcgagt gcgagtggag cgatgccgga cagagcgccg
    23281 acagtcgcgt tgttgaggcg tagtcgggtc ccttcgttga ggccgacggc gtgtacgacg
    23341 ttggcccaga tgctggtgag ggtggcaacg ccgacgagcg cccacacgta caggcgggag
    23401 cgcagcgggg ccccgcgcag gatgagcaga gcaacgatgc cgatggcgat gaacccgtcg
    23461 atcacgaggg ggaagaggta ggtgagcagc ccgcgcacat ggctggcgac ggccatctgc
    23521 cgcagcgcgt cgtaggagag tgcgaagccg atggtggcga gcaggacgat gccgacgcgg
    23581 atggtgaggc tgccgcggac ggcggccggg gctgtcggtg caggggaagg caaggcaatc
    23641 gctccgggaa cgcagggcac tggggcttga ggagaggtgc actcccacgc ggacccctct
    23701 acaaggaggg ggccgcgcgt gagtaaccgg tggtgtgagg tgtgtgtggg ttcgcgtgag
    23761 cttctgacct ggtcttttac cggctgggta gccccgcgtg aggggcctgt gagtccgtcg
    23821 ccgggacctg ggccgtgagc gccagcgtga gtcgccgttc cggcgccgga cgcctccccg
    23881 gcaccggaac ccatttccgt caggagacga cggccatgtg tcgtgccgtg gcccggtagc
    23941 ggacctggcg gctgccgccc ggctcctgtt ccttggtggc ctgcccgacc tcgtggaggg
    24001 ccttcagcgt gcgccgggcc ctctcctgct ccttggcgct cgggtccgcc tctccggtca
    24061 tcagggccgc gagttccctg ctggtgaggc cgcccggtgc atcgcgcagc agggtgtacg
    24121 ggtcgagggg tacgtcgacg cgcgaggtgc cgcgccggtg gtcgtggacg accgtgaggg
    24181 ggccgatctc accggtcacc gtcttggcgt ggtggagctt gaccgtcgcg tcgcccgctc
    24241 ccccgctcag aaacatgacg ctgcccgcac ccgccgtgaa ccaggtggtg ccgtacacct
    24301 tgtccagcgt cgggcgtccg ccgggcttgg cgtccgctgc ggacttgcgc tggtggtgca
    24361 gttccagcag ttcggcgccg gaccgcagca gctgctggcg ggcgcggttg taggcaccga
    24421 cggcctcgtc gtcggtgagc ttgccgacga tgtccttgac actgtcgatg accacggtgt
    24481 cggcgtcgtg gtgggcggcg agttcggcga gcaggttcgg ctcgcggtcg agcgtggccg
    24541 gaagcggtcc tccccagacg acgagccggt cgcggagggt ctcctcgtcg atcgggcgta
    24601 ccaggcgtcg cagggcacgg gcgatctgcg gcggccggtc catggcgagg tagagcacgc
    24661 gcctgccctc ggtgacgggc atcccgagca ccagcgcctg gaagccgagc cgagccatga
    24721 cgagctggtg ggcgatggtg ctcttgccga cccccggcgg gccgaccagc atcaggctct
    24781 cgccgctcgc ccatcccgtc tgctcgggcg tgccccatac cggcgggacc tcggtgccga
    24841 ggctgttgac gaagtcccag ccgtcgacgg cgaaccggct gagcctgccg ccaccactcg
    24901 atccgcgcca gtcggtgctg tcgagggcgc tctgcagcag cacgcgtatc tgggcagggt
    24961 cggcgccttc tgcaccgctc tgctgcaggg tgtgcaccgc cgctgcctga aggcggcgca
    25021 gctccgcctt ctcccgcacg atctcggcgt agtagtcgca gttggccggc ccgggggtcg
    25081 cgccggcgag agtgtggagg tagggggatc cgccgacgcg ggtgagggcg ccgacccgtc
    25141 cgagttcctc gccgagcgcg atgggatcgg tgggcgatcc ctcgtcgcgc agggagagca
    25201 gggtccgcca gatgtcgc
//
