LOCUS       NZ_CP045096            25257 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Streptomyces phaeolivaceus strain GY16 chromosome, complete genome.
ACCESSION   NZ_CP045096
VERSION     NZ_CP045096.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces phaeolivaceus
  ORGANISM  Streptomyces phaeolivaceus
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 10116136)
  AUTHORS   Mo,P.
  TITLE     Streptomyces sp. strain GY16 isolated from leaves of Broussonetia
            papyrifera
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 10116136)
  AUTHORS   Mo,P.
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2019) College of Life Science and Technology,
            Central South University of Forestry and Technology, No. 498,
            Shaoshan South Road, Changsha, Hunan 410004, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-AUG-2019
            Assembly Method                   :: HGAP v. v. 1.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 120.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_009184865.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:51:11
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 9,113
            CDSs (total)                      :: 9,024
            Genes (coding)                    :: 8,642
            CDSs (with protein)               :: 8,642
            Genes (RNA)                       :: 89
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 68
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 382
            CDSs (without protein)            :: 382
            Pseudo Genes (ambiguous residues) :: 0 of 382
            Pseudo Genes (frameshifted)       :: 112 of 382
            Pseudo Genes (incomplete)         :: 305 of 382
            Pseudo Genes (internal stop)      :: 23 of 382
            Pseudo Genes (multiple problems)  :: 53 of 382
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-12 20:44:39
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3167193
            Orig. end                         :: 3192450
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP045096.1.
            Bacteria and source DNA available from Yunlin Zhao.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25257
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="13"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..25257
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25257
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:15257](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15257
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            complement(294..1535)
                     /locus_tag="F9278_RS14695"
                     /old_locus_tag="F9278_14705"
     CDS             complement(294..1535)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000949.1"
                     /locus_tag="F9278_RS14695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14705"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_152168740.1"
                     /transl_table=11
                     /translation="MADPFAELLLRLRKDAGRTQEQQAAAINAVSGRDTMTRREISRYE
                     RFENVPTNHTLEQIAAACGVSFEDLRREAKAARARKRKDSAREEEDQEDVKRRTLLGGA
                     AIGVSAAAEPWGRLALALSRGSKADAPSVAALVDRAAELHIQELGLSARRLQRTVESHL
                     DAITAALPRAGEHERALTVAAGETAALAGWVAWDLGETNKADAYYQVTSECASAAGHPP
                     LRALALTYASYGTPTPKERLRLLSQAAQDVRGHGNATAAAWVLGRHAEEAAALGDDTEA
                     LRALERARFAYDFADHTSEQAWVRFVTPYRMDSLALSVYGQLGRSELSATADTAVERLG
                     DGLSDGGVVVLGDLASALLRGGDVEQGVYVTRQFAAASQAKPNTMGKERARAIATWLPD
                     NERELADHLRKFAS"
     gene            complement(1576..2334)
                     /locus_tag="F9278_RS14700"
                     /old_locus_tag="F9278_14710"
     CDS             complement(1576..2334)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000950.1"
                     /locus_tag="F9278_RS14700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14710"
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /protein_id="WP_226966739.1"
                     /transl_table=11
                     /translation="MTTGVTRWTGREVALLREALRMIGKDFSAKVGISTRQLVNWEGRG
                     ESIKPHPNNQAALDTLLSTSSPDAQWRFAQLLTEQAAVGHDERTEELLRRDPRTIRHLV
                     DGKVMVLIEEGIYPTTNLDYEQFIRATGHRPPQHWTGRRCPSALYDHPVVWVTWHDADA
                     YARWAGKALPTASLLLGKKERASTRQPGCVAESVSPQPRSGRRDGPPRERGRCRPAERR
                     HGPIASRVRAPDQGNSEGEKSVKGGNWRGN"
     gene            complement(2350..3153)
                     /locus_tag="F9278_RS14705"
                     /old_locus_tag="F9278_14715"
                     /pseudo=""
     CDS             complement(2350..3153)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019984976.1"
                     /locus_tag="F9278_RS14705"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14715"
                     /product="aminotransferase class IV family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MLGGVATLDGNPVSADDLLPLALTNFGHFTSMRVDGDGSIRGLTL
                     HMERLVRDCKTVWGADLDTALVRDYVRRGLEGQSGPCVVRVTIYDPRAEMGHSADADEP
                     HILVSVRSAGALPPEPLRAMSVPYERDLPEVKHVGLFGALNA"
     gene            3360..3794
                     /locus_tag="F9278_RS14710"
                     /old_locus_tag="F9278_14720"
     CDS             3360..3794
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024970.5"
                     /locus_tag="F9278_RS14710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14720"
                     /product="ATP-binding protein"
                     /protein_id="WP_152168741.1"
                     /transl_table=11
                     /translation="MSPATAVAPAATKAPPQTSRAFDLAFTPAPPLVRQARRITRAFLR
                     LWNVNGELAENIVLAVSELVTNAVEHGTGDVGLRIQYPDGELRIEVTDDNPAPAELRHA
                     DDEELSGRGLFLIAVLARTWGVSDDGRTTWCVFRVPARRS"
     gene            4373..5038
                     /locus_tag="F9278_RS14715"
                     /old_locus_tag="F9278_14725"
     CDS             4373..5038
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378931.1"
                     /locus_tag="F9278_RS14715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14725"
                     /product="DUF6415 family natural product biosynthesis
                     protein"
                     /protein_id="WP_152168742.1"
                     /transl_table=11
                     /translation="MTRLVFIETASVSEDPDERHVQLLLMRGHLMRLLGAVVPVDANEP
                     PLEGDRLVSRVRALLDEEIPGDAVHAAPLHRRMSEVGRELLAILPTVDASDDVVDGWGR
                     TVCAGFDSTRIREAIRAAKSWEQAGVYPHPHTLAAVTQALSGYVTTLVPYVSIHMESLS
                     AGSRGWSACGGAIERSQEARDVAPAEGLKAARKHAYRLAVHTEALLRYAEQDCERDGE"
     gene            5351..5842
                     /locus_tag="F9278_RS14720"
                     /old_locus_tag="F9278_14730"
     CDS             5351..5842
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000954.1"
                     /locus_tag="F9278_RS14720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14730"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_152168743.1"
                     /transl_table=11
                     /translation="MPAPDETISPPLSPQEREALLGISQGRTTSETACDMGVSDSTVKT
                     YILRIGGKLGTCERAGMVDLAYRHGHLDVPGPVDHVVELPEEQRTVLAGLAGGKTVEEI
                     AADEKRPLDDVRKDARRLLRALGASSAAHTVTRGWQFRLLGPATGRENSGNVVSVAGQA
                     "
     gene            5839..7008
                     /locus_tag="F9278_RS14725"
                     /old_locus_tag="F9278_14735"
     CDS             5839..7008
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013000955.1"
                     /locus_tag="F9278_RS14725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14735"
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="WP_152168744.1"
                     /sec_met_domain="PCMT (E-value: 1.7e-10, bitscore: 40.0,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNARVEAGSLRPGSGHVHQHAGDVFTCDRRQDFVPNVIRTHRGGR
                     WRRVDRSKNAGEWAKFVHRSEMLVFDVDDGGEGGPGIVTGVISSKEDVAARLAALAPVL
                     GTAVAEIGTDCGWTAACLEHLLQGGQVVTVADTERLAEIARQRLRPYPRVRVVSGPAAG
                     VLGPAGSFHGLLSHRAVRRVPWEWVTRVRPGGRVCLPVRTALGGSSTLLVLTVARDGAS
                     ASGRFHAGPAPQTVWLREHRPGEGTSVESQGSPRASEALDARRAHVRPAARLFAGLLRP
                     DLRMQVVRGVAQLEGDVADRLRIHDHQASRAVVFLHSPRIYEWGPRDLGSDLFDALGQW
                     HAAGEPEVEQLGVTITETEHTLWLGAPDGPSWRLPELHTITGEVERHAT"
     gene            6998..7840
                     /locus_tag="F9278_RS14730"
                     /old_locus_tag="F9278_14740"
     CDS             6998..7840
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378920.1"
                     /locus_tag="F9278_RS14730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14740"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_152168745.1"
                     /transl_table=11
                     /translation="MRPDHPMLLHPSAAIAELQARPSSARMQNYLLGGRDNYIVDRDGA
                     RRAADRMPFLESAVRHERRYVLLMVQALAIAGIRQLVDFGCGLPHGPTPVDVLTRIHPD
                     ARAVCIDNDVLVHTHAEGMMTAKAPAVVASLCADVRAPESILVSREILETINWREPVIL
                     LLGSVLHHIEDTETQPLTVLVDQYKHVAATGSALVITHATADVSGKPVRKFAKTMTAAG
                     CPVHLRTKEQISRLFDGWQLTAPGLTAPQTLTLEYPVLPQAASYAGTARKETAHGRAV"
     gene            8425..9648
                     /gene="fxlM"
                     /locus_tag="F9278_RS14740"
                     /old_locus_tag="F9278_14750"
     CDS             8425..9648
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378734.1"
                     /locus_tag="F9278_RS14740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14750"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_152168747.1"
                     /sec_met_domain="PCMT (E-value: 5.4e-37, bitscore: 126.6,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVTVAPDEATRLRNKVVDQLKEDGTIVSPAVEAAMRKVPRHLA
                     VPEAPLSDAYSTYNAVITKEDEHGNHTSSVSAPQIQAMQLEQASIRPGDNVLEIGTNGP
                     NAAYLAELVGPTGQVTTVDIDPAPADRAKRFLTETGYTGVNVVVADAENGLPGNAPYDA
                     IVVTVGAWDIPPAWIDQLKDDGRLVVPLRINGLTRTYGFVRQADHLVATSAHVCGFVAA
                     QGAGSHTQQVMQFPGEEGVTLRFDEGLPANPSLLDGVLDSARAETWTGVTVASQEPIGT
                     LQMYLSTQVPTYCFMSADPELTTGRIGPTGSGWSMVAIDGPHFAYTVVRRDTEKKTAEY
                     GVHAFGPDAAEFAERITDIFRTWGEKVRGSDGPRIAVYPAGTPDDRITGDRIIDKRHSR
                     ISISWPAV"
     gene            9707..9913
                     /locus_tag="F9278_RS14745"
                     /old_locus_tag="F9278_14755"
     CDS             9707..9913
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379227.1"
                     /locus_tag="F9278_RS14745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14755"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_107446631.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 2.4e-15, bitscore:
                     55.2, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTAVLHSVPAPVGLPVDALADDDFELDIRVVISESPLTVFMCPT
                     SDGCGNTCVNGASACQSSIEDAA"
     gene            10001..13051
                     /locus_tag="F9278_RS14750"
                     /old_locus_tag="F9278_14760"
     CDS             10001..13051
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006378945.1"
                     /locus_tag="F9278_RS14750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14760"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_152168748.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 1.4e-205,
                     bitscore: 683.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 2e-19,
                     bitscore: 69.1, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 4.3e-13, bitscore:
                     48.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHGIPLTYQWQPGMLLRASTASRPIPVPDFDLHGDDATIRSRQW
                     LEEVWRAPVPTALSAASPVLCQRVAEILNGTVTDGRRIRRAVRSVAAYLLRWNHRPTPF
                     GVFAGVAPAEPAQAAHILWGEGYRTVLRPDSDWLTDVITRLESHPALLARLTVVANNTG
                     RSRGNRHVVDGMPADAHTSGYAPIELSVRLTRPVAAVLEAARTPIPYELLVHRLSGQFP
                     TARPEQLAGLIADLLNKHILISSLWPPMTSVDTLAHICDELEKADATGIPDSAELASQL
                     ASIRGGLKHPDTVAPWTLSDPLTQSMQHVIATGRVPLLVDAALDCTTHIPEALLAEAAE
                     AAQVMHQLSPHPYGYPQWRDYHQRFLDRYGSEAIVSVLDLIADSGLGLPAGFLGSERAR
                     PPYEMTDRDEKILRLLQEAMLDGRRELLLTRATIADLTAGHTEPLLPMPRAEIAVEIHA
                     PSLEAVQGGDYRLLVTGAPRPGSSMLGRFAHLLPPSAQSALTDSYATAGPGAIAAQLSF
                     TPRRRRNENITRTMQVLPFTIPLGQHHEPGPGVIPLDDLAVTADTRRFYLVRRSTGQHV
                     EPRVTHALEASVHTPPLARFLAEITTARSAAYRAFTFGVAATLPYLPRVRYKRTILAPA
                     RWLLSAEELPGRSAPMADWDKALARWRERLCVPDHLALVEDGQQLPLDFDQRIHRALLR
                     AGVDRNRVVELRESTTARDWAWIGRPHELLIPLANSTPADAPRLPEAAAAATGTPSQPT
                     VLYARLFAHPQRYDEILTGHLPTLLDQFDTMPLWWFRRHRDTIRPASDQHLDLYLRLPD
                     PAAFGAAAQQVTGWADALGSQRLASHLELTTYPPKSGPYGHGSALDAAHLVFAADSAAG
                     VAQIRAAADDAAIGQALTAASMFDLTVRFTGDADQASDWLIRALPQEHGPLARERVTLA
                     LALADPEHAVLQALPGGPDVIAAWGQRAAALTAYRQQLSTERNADSVLRSLLHEHCVRA
                     LPVAPDHERATGRLARACALRHRERQP"
     aSDomain        10466..10747
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F9278_RS14750_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="6.30E-22"
                     /identifier="RREFam001.1"
                     /label="F9278_RS14750"
                     /locus_tag="F9278_RS14750"
                     /protein_end="249"
                     /protein_start="155"
                     /score="69.1"
                     /tool="antismash"
                     /translation="TVVANNTGRSRGNRHVVDGMPADAHTSGYAPIELSVRLTRPVAAV
                     LEAARTPIPYELLVHRLSGQFPTARPEQLAGLIADLLNKHILISSLWPP"
     gene            13048..14274
                     /locus_tag="F9278_RS14755"
                     /old_locus_tag="F9278_14765"
     CDS             13048..14274
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379019.1"
                     /locus_tag="F9278_RS14755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14765"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_152168749.1"
                     /sec_met_domain="LANC_like (E-value: 1.5e-42, bitscore:
                     144.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTATTSPAVLAETFARHLATPVPPPEDQPWAAQDLAAGAAGSAL
                     LHIERARTGDGTWQQAHPWIKTAVATPVSAADTSGLYLGAPAAAFMLECAVTAEAPRYQ
                     DALAALDHHVAQLAHRRCDAAQTRIRQGRPAGFHEYDIFYGLTGIGAYLLRRSPSGTAM
                     ARVLAYLVQLTRPIRHGDQGMLPGWWVDHQPDLTPSTVPAGHANFGAAHGITGPLLLLA
                     RALRQDVKVDSQEDAIDTILHWLDTWRQDGPAGFWWPEHLRLGELRTGRPSQRGPARPS
                     WCYGAPGIARAGQLAALARRDPARQRLYEDALVRCLTDPDQLSKITDAGLCHGWAGVYQ
                     TAFRAAHDAATPALRATLPDLAAALTRHTQPGHDPGLLQGAAGTALALTTAAHDAAPTS
                     GWDTCLLID"
     gene            14256..15257
                     /locus_tag="F9278_RS14760"
                     /old_locus_tag="F9278_14770"
     CDS             14256..15257
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379081.1"
                     /locus_tag="F9278_RS14760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14770"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_152168750.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 5.8e-38, bitscore:
                     130.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTDRLNQPSLLEATLHAVLDVLAGTDTDTAAARAGLEPADLDAA
                     VAVYQQAGQQALAQQSGPLAWRQLFIRFTDWGKAEQTAAEYIAPVLDLAQQDALINGWW
                     FIRKHPCWRMRLLPAVGTQLPPALADTLDELTAAGRVHRWWPGIYEPETAAFGGDTSMT
                     IAHTLFHADSHAILTTTHGELGRRELSLLLCATLMRAAGLEWYEQGDVWHRVTRERPLL
                     SDVPAAKVHAMADSLRQLLIADTSASGPMLHSDRTLKPATDWVSAFRQAGGDLGTAARD
                     GALDRGLREVISYHVIFHWNRIGLSARTQSVLAHAARTAILHPADPTERPML"
     gene            15254..16390
                     /locus_tag="F9278_RS14765"
                     /old_locus_tag="F9278_14775"
     CDS             15254..16390
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015662444.1"
                     /locus_tag="F9278_RS14765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14775"
                     /product="hypothetical protein"
                     /protein_id="WP_152168751.1"
                     /transl_table=11
                     /translation="MTPPPHHSQARIRRLSRRFPLVSRSHLVYPSFAARIDEVRTCGEK
                     SAQDGPLVDRINLACATWNLSALIASDCGLTNLATDLCLRQLRLFQAAWPVTEDTAIAS
                     LQPIVNLVRLTARTGDPQAAYQQLMNVHRAAHDGGTVTVHGQTIDLTGFTTEATLDHIR
                     PWLHDLLLDDGTRLLVAAGHWRQAAEHATAYDKEPERLYGSRQAHVVASLHTDAQDMTN
                     FLIDKATITEPWEEAVAQILRHYADRLACRATAKGFAATALAVRDALEPAPPHLRMFRV
                     RLALAAIDLVPEGCEILARPLYDAIVSDTTQACDAYAAREILRHPAPPAEQRSRHELEA
                     IVHDSGLGRGTLPEPVLSTMMRAVSTAGANLAQCLTQD"
     misc_feature    16475..16490
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.73"
                     /tool="antismash"
     misc_feature    complement(16526..16541)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 18.61"
                     /tool="antismash"
     misc_feature    complement(16527..16540)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.38"
                     /tool="antismash"
     gene            16838..17014
                     /locus_tag="F9278_RS14770"
                     /old_locus_tag="F9278_14780"
     CDS             16838..17014
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F9278_RS14770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F9278_14780"
                     /product="hypothetical protein"
                     /protein_id="WP_404819043.1"
                     /transl_table=11
                     /translation="MGVVLAVAVWLLIRKGGLKVGHAIAAVLLGFYLRDSSLAPSISRG
                     VQSVAEMLSGIRI"
     misc_feature    complement(17179..17194)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.66"
                     /tool="antismash"
     gene            17315..18799
                     /locus_tag="F9278_RS14775"
                     /old_locus_tag="F9278_14785"
     CDS             17315..18799
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="F9278_RS14775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14785"
                     /product="ATP-binding protein"
                     /protein_id="WP_193241483.1"
                     /transl_table=11
                     /translation="MAVAVGTTARVHVDGWIIGAVVAAAGLGVLVGADWLAVRTAAELH
                     RQRSEYSDSVHGWLRHFQSGVDEGRKSISAAVEQLNRGERPTPPAFSAGQAGSGSNPWS
                     DAEVALYQLHAEAWRAVVNGRQAELPQALVYIAGGMTLLLVRALGIVTELTNQVQDPDL
                     LYRVYDVNNLLKRMRRSAGRLAVLGGVKARTLHQPLGLVQLLRGASGEIEKYARVRMHT
                     STLDVQIPGFAGPDLIHLLAELEENATLCSPPDSKVVVRTSRVTAGLAVEIEDRGIGMA
                     QGELDRYNRMLADPRDRDLAEQLAQRQTGLLVVAKLARRYGIHVQLQKNLMHGTTALVV
                     VPDKLLLWAGESAPVSHAEPAADVAAVPGPSALSAGRPGPRPAGGPRPSPPAPVGTASL
                     PSRNARRAPAQQPAASATTRATPSRGAAPGSRPRLPQRTPQATVHERAAPAEPEATPVP
                     LAPPDPSFVSKFAQGVHRAEQAAAGREARPPEASAG"
     gene            18888..19370
                     /locus_tag="F9278_RS14780"
                     /old_locus_tag="F9278_14790"
     CDS             18888..19370
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015232.5"
                     /locus_tag="F9278_RS14780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14790"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_193241484.1"
                     /transl_table=11
                     /translation="MTMTTDSTAAQPDRVVDELLNDLAKVPDVTGVLLGSQDGLRLAYA
                     GPGMDGQMVDRLAAVINGLYSIAHGVDDGEGRVEQVLIRKTNFLLFIMSAGSPPAAVAL
                     NAGRDPDKVESVLGVLTNTRADEGTVGFAMANMIKRMGELLATPARAGGAPSGDGQ"
     gene            19372..19737
                     /locus_tag="F9278_RS14785"
                     /old_locus_tag="F9278_14795"
     CDS             19372..19737
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017170.5"
                     /locus_tag="F9278_RS14785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14795"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_152168755.1"
                     /transl_table=11
                     /translation="MASASSPAWTVEDTEAPSLYVLTGGQTRPTHDLQIETLLWAEGEP
                     PSGQPPEADQAMALCREQPLAVAEISALIGLPFQITRILMSRLIDIGALSAVTTPHSAD
                     LPDVALLKALRNGLLKL"
     gene            19718..20347
                     /locus_tag="F9278_RS14790"
                     /old_locus_tag="F9278_14800"
     CDS             19718..20347
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006379151.1"
                     /locus_tag="F9278_RS14790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14800"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_152168756.1"
                     /transl_table=11
                     /translation="MDSSSSDPRPARRFGRAKPTPVKIVVSGGFGVGKTTFVSAVSEIT
                     PLRTEAVITRVSEGVDDLSLLVDKTATTVGMDFGRITFPQLNAVVMLFGTPGQTRFWFM
                     WDELTRGALAAVVLVDTRRLDESFPAVDYFERLGLPFLVAVNVFDDASHYDPDEVASAL
                     ALPSTVPVVLCDARLSTDATGVLARLIDHVLTHSYSPAAVLQGAQL"
     gene            20344..20880
                     /locus_tag="F9278_RS14795"
                     /old_locus_tag="F9278_14805"
     CDS             20344..20880
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013736.5"
                     /locus_tag="F9278_RS14795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14805"
                     /product="GAF domain-containing protein"
                     /protein_id="WP_193241485.1"
                     /transl_table=11
                     /translation="MNPHAPSDLLSTTRHDTDWQSHLPEVFDPMAPPVEAFDAFARQVA
                     DVLGTPYAMLNWVGDEQYFLGLANPADSELPVLGRTLPLTHGFCPHVVQRRGSLVLTDV
                     LDFDAFAGNPVVDELGVRMYAGAPLIDKRTNHVWGTVCGIDIEPRARSQGRPVWTRIDH
                     MRDLLMTELYLRTSP"
     gene            20946..22175
                     /locus_tag="F9278_RS14800"
                     /old_locus_tag="F9278_14810"
     CDS             20946..22175
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016325326.1"
                     /locus_tag="F9278_RS14800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F9278_14810"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_226966740.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.5e-20, bitscore:
                     72.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 6.2e-22, bitscore:
                     76.7, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.3e-27, bitscore:
                     95.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTADLTPDYEALVQHFDEFATAEVAPRVQRMESSPHAVERDL
                     ALLMAEQGWFGATIPRQYGGMHAGHLAKTLMIQRMARASGAAGAILQASQLPVSMLIHF
                     GSDEQKALLLPQVSCGDTLLSIAVTEEETGSHVLGMETTARRDGNDWILDGSKVHIGNS
                     HIAHFHCVVARTASADTAGSRALTAFLVEHDRDGLTVEPHRPALGLHGFTFGKLTFDGV
                     RIPEANVIGEVGDGKDIAYSSSILYGRPNLAAVSLGIHEAIMECAAGFLQGRRRYNGAL
                     ADLPVLRDRVGDMKSRLMASRDLAHHAVRMLDSGRPCDDLLINSKYLNHKWAVQSGQDA
                     MELHGAHALRTDYPLQRLWRDVQHTYAPAGTGEVQRQRLAETELGAPPIQWSERLAAKT
                     SLFLPTSTAA"
     misc_feature    complement(22534..22549)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            22545..23429
                     /locus_tag="F9278_RS14805"
                     /old_locus_tag="F9278_14815"
     CDS             22545..23429
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F9278_RS14805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F9278_14815"
                     /product="zinc-dependent metalloprotease"
                     /protein_id="WP_193241486.1"
                     /transl_table=11
                     /translation="MTIIDVPNETRGHSGLAEEIEQILRDTASLIQEVTDLSCPTLVFR
                     LLTPRAWRAEIRAWAERSLEEDLAQARLTAPEADRVRGRLTAWDASDLRPGWPMNPGLT
                     ITDHYGEPRTLITPQALHHTGVRYDRTALIRFVVHAGVHHAQIAASTGTLPPPPIRAAA
                     RVHEDSATRTLMEGHATWAEQKVAGAYFGFCREHRPREVPRSWRYRQHARLIPWLQPPA
                     DLTSLMCARAADPSPPAREDGASFVQAVIEVSGSVAPFNRIWTDPSLAPTNREITHPEA
                     WFSRVSIEGPALL"
     misc_feature    complement(24060..24073)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     18.15"
                     /tool="antismash"
     misc_feature    24831..24846
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.12"
                     /tool="antismash"
ORIGIN
        1 gagcaagctg gcagcgggcg ctcacatcga cgcacccatc accgccgtct actggtggaa
       61 gagtgagatc gagacggcgc gggagtggcg gatctcgtac atgacgaccg caggccgcct
      121 gccggagctg gaggcgtggg tgtccgagag gcactcgtac gaggtgcccc agtgggtcac
      181 ccttcccgtg acaggcggat cggacgctta cctgtcctgg gtcgttgagc agacgaccca
      241 gcgctgacgc gctcgcctct tgggcgagtt ctgcgacgga tgtggcacga gcctcaagac
      301 gcgaacttcc ttagatgatc ggcaagttct cgctcgttgt cgggtagcca ggtcgcgatg
      361 gctcgggcac gctccttgcc catcgtattg ggcttggcct gactcgcagc cgcaaactga
      421 cgtgttacgt agacaccttg ttcgacatct ccaccgcgta gcagcgcgga agcgaggtcg
      481 ccgagcacga caacacctcc atccgatagg ccatccccga ggcgttcgac ggcggtgtcg
      541 gccgtggcgc tcagctcgga tcgtcccaac tgtccgtaca cggagagtgc cagtgagtcc
      601 atgcggtaag gcgtcacgaa tcggacccat gcctgctcac ttgtgtgatc cgcaaagtcg
      661 taggcgaaac gcgctcgttc caatgcacgc agtgcctctg tgtcgtcgcc gagcgccgca
      721 gcctcctcgg cgtgcctgcc gagcacccag gcggcggccg tggcgttgcc gtggcctcga
      781 acgtcctggg ctgcctggga aagaagcctc agcctctcct tgggcgtcgg agttccgtag
      841 ctggcgtagg tcagggccag ggctcggagc ggagggtgtc cggcagccga tgcacactcc
      901 gacgtgacct ggtagtaagc atcagccttg ttggtctccc ccaggtccca ggccacccac
      961 ccggccaggg ctgcggtttc tccggcggcg acagtaagag cccgttcgtg ctctccggca
     1021 cggggcaaag ctgccgtgat cgcgtcaagg tgagactcga ccgtgcgctg caaccggcgt
     1081 gcgctgagtc cgagttcttg gatgtgcaac tcagcggctc ggtcgacgag agcggccacg
     1141 gaaggcgcgt cggccttgga acccctactg agggcgagag cgagccgtcc ccatggctcg
     1201 gcagccgcgc tcactccgat ggcagcgccc cccaacaacg tgcggcgctt cacgtcctcc
     1261 tggtcctcct cttcacgagc ggagtccttt ctcttcctgg cgcgagcggc cttggcctcc
     1321 cgcctcaagt cttcgaatga gacgccgcag gccgccgcga tctgttcaag cgtgtggttg
     1381 gtcgggacgt tctcgaaccg ttcgtaacgg ctgatctctc gacgggtcat ggtgtcccgg
     1441 ccggagacag cgttgatggc ggctgcctgc tgctcctgcg tccggcctgc gtccttccgg
     1501 agccggagga gcagttcggc gaacggatct gccatgagtg tgacctctgt ccgggagtgg
     1561 aatccaatca tggcttcaat tccccctcca gtttcccccc ttgacagatt tttccccctc
     1621 cgaattcccc tggtccgggg cccggacacg cgatgcgatg ggcccatgac gacgttccgc
     1681 agggcggcac cgcccccgct cacgaggagg accatcccgt cggccggacc ttggctgagg
     1741 agagaccgac tctgcaacgc agccaggctg tcgggtcgag gctcgctcct tcttgcccaa
     1801 gagaaggctg gcggtgggca gcgcctttcc cgcccagcgg gcgtacgcgt cagcgtcgtg
     1861 ccacgtcacc cagaccacgg gatggtcgta cagggcactg gggcaacgcc gcccggtcca
     1921 gtgctgcggg ggccggtgcc ccgtggcacg gatgaactgc tcgtagtcaa ggttagtcgt
     1981 cgggtagatg ccttcctcga tcagcaccat gaccttgccg tcgaccagat gtcttatggt
     2041 gcgcggatcg cggcgcagca gctcctcggt tcgctcgtcg tgccccaccg cggcttgctc
     2101 ggtgaggagc tgagcgaacc gccactgggc gtcgggggac gatgtggaga gcagggtgtc
     2161 cagcgcggcc tgattgttgg ggtggggctt gatcgattca ccccgcccct cccagttcac
     2221 gagctgcctg gtgctgatgc cgaccttggc ggagaagtcc ttaccgatca tgcgcagcgc
     2281 ttcgcgcagc agagcgactt cccggccggt ccaccgtgtg acccccgttg tcacgctcgc
     2341 cccctacggc tacagggtct cgccgaggat ggccaggtac gtctcacgga gcacagtcag
     2401 cacggggtgt tcagtcggca gttccttatc gtcgatcgca gacagggccc gaaccccgat
     2461 gctggtgttc gtcgcgaaga ccgccgccat ctgcttggcc tgatcgaggg tgacgggggc
     2521 ggtgcggtgc tcgacgccat tggcgtgctt ctggaggagc gccatcgtca caccgggcag
     2581 gacgggcgcc tgcggccaca ccaccgttcc gttgccgtcg atgaaggcga cgttccaggt
     2641 gccgccctcg ctcacgagac tgtcgcggcc gacgaacaag gcgtcgccga accctgcgcg
     2701 ctgcgctgcc cctcaggcgt tcagggcacc gaagaggccg acatgcttta cctcgggcag
     2761 gtcgcgctcg tacggcacgc tcatggcacg cagtggttct gggggcaggg cgccggcact
     2821 gcgtacggac accaggatgt gcggctcgtc ggcgtcggcc gagtgtccca tctcggccct
     2881 cgggtcgtag atcgtgactc ggacgacgca cgggccgctc tgcccctcca ggccccggcg
     2941 gacgtaatcg cgaacgagcg cggtgtccag gtccgcgccc cacacggtct tgcagtcccg
     3001 tacgagtcgt tccatgtgca gcgtcaggcc ccggatgctg ccgtcgccat cgacgcgcat
     3061 ggacgtgaag tgaccgaagt tggtcagggc cagggggagc aagtcgtctg cggacacggg
     3121 gtttccatca agagttgcca cgccacccag catctcaggg ccgtccattc ctccggcacc
     3181 ccaatcgggg ttactgacga gtcaacttcg ttgaaacttc cttcccattg cgatgccaca
     3241 cagtgttcgc ttgtcaccgt gcgaacacgc ctggtgatcg atggaacgag gcgtgccacg
     3301 cgacgcaatg acgacgtatg ccgcacgatc ccccacaccg cccactcggg aggccctcga
     3361 tgagcccggc tacagccgtc gcgccggcag ccacgaaggc gccgccgcag acgtcgcgcg
     3421 ccttcgactt ggcctttacc cctgccccac cccttgtcag acaggcacgc aggatcaccc
     3481 gcgcattcct gcgtctgtgg aacgtgaacg gcgaactggc cgagaacatc gtgctcgccg
     3541 tctccgagct ggtcaccaac gccgtcgagc acgggaccgg agacgtggga ctccggatcc
     3601 agtaccccga cggcgaattg cggatcgagg tcactgacga caacccggcc ccagccgaac
     3661 tgcgccacgc tgacgacgag gaactgtcgg gccgcggcct gttcctcatc gccgtcctcg
     3721 cacggacgtg gggcgtcagc gacgacggca ggacgacgtg gtgcgtcttc cgcgtccctg
     3781 cgaggaggtc gtgatgaccc cagtcactcc tgaagccgca gcaggaatga gccagcgacg
     3841 ctccaccaac gatgtgaatg cattacttgc atcctcatcc ccttccatgt cctcaacagc
     3901 gccatctgag gggcggatca gaaagcctca gcctcaacga cgcgccgcgg ttgggttgct
     3961 tgaccccgat agtgatccgg acggcaggac gtcccaggac gtcccgacag agtcctgtgc
     4021 ggcggtaccg gcgtctccga gctccctgaa cgatgccctt gtagctcgcc gcaccgtgtc
     4081 ctccttgaac gaaccgccct tgtcggcgag tggcggctcg aaatgcctcg gcggctcctc
     4141 ttcaggggcc gccgaggcga cgccccgatc gccaacttcg gacctagcta gtggagttgt
     4201 ccttatgcct cgcaccacaa cctcggcccc tccagtcggc ggtcggcagg tggacggcgg
     4261 ctcctggccg gagggctcat tccaggaact tggctgtgaa ctgaggaccg ttgtatcgac
     4321 cctcgcaccc aggccgtcgc ccctcgcggt gcaggagacc cttcatcatg aagtgaccag
     4381 actggtcttc atcgagactg cctccgtcag cgaagacccg gacgagcgac atgtccaact
     4441 acttctcatg cgcggccact tgatgcgact gctcggagca gtcgttcccg tcgatgccaa
     4501 cgagcctccc ctagaagggg atcgattggt ctcacgcgtg cgtgccctac tcgacgaaga
     4561 gattcccggc gacgccgtgc atgcggcgcc cctgcaccgg cggatgtccg aggtcgggcg
     4621 ggaactgctc gccatccttc ctactgtcga cgcctctgac gacgtggtcg acgggtgggg
     4681 caggactgtg tgcgccgggt tcgattcgac gcgtatccgc gaagccattc gtgcggcgaa
     4741 atcctgggag caggcggggg tgtacccgca tccgcacacc ctcgcggcgg tcacgcaagc
     4801 gctcagcggc tacgtcacga cgctcgtccc ctacgtctcg atccacatgg aatcgctctc
     4861 cgccgggagt cgagggtggt ccgcatgcgg tggggcgatc gaacgctcgc aggaggcccg
     4921 cgatgtcgct ccggcagagg ggctcaaggc ggcgaggaag cacgcatacc gtctcgcggt
     4981 ccacaccgag gccctgctgc gctacgccga acaggactgc gagcgggacg gtgagtgaca
     5041 tggccaggac ctatcgcgcg gcgcaccctc agcggattca ccgtgctccg gcctccccac
     5101 caaattcggg ctccccccgc aaagacgagc cagccccagg gcgcgtccga cgtggctggc
     5161 gacaggctcg cgcgcaccga ggcgccgtcc tcctcgctac cgccatcagc ctgcctaccg
     5221 tctacgtcct cgccgaactc gccctgcagc tctacggcgg ttcgtagctc acgccccaac
     5281 cagccgacca gcaaagtggg ccggccccga taagacgacg actgttccag aacaccgaag
     5341 gagtacgacc atgccggccc cggacgagac catctcgccg ccgctttccc ctcaggagcg
     5401 ggaggctctg ctgggcatct ctcaggggag gacgacctca gagacggcct gcgacatggg
     5461 agtgtccgac agcacggtca agacgtacat cctccggatc ggcggaaagc tcggaacttg
     5521 cgagcgggcg ggcatggtgg acctcgccta ccgtcacggg cacttggacg tccccgggcc
     5581 tgtggaccac gtcgtcgagc tgccggagga gcagcgcacc gtcctggccg ggctcgccgg
     5641 cggaaagacc gtcgaggaga tcgcggccga cgagaagcgt ccgctggacg acgtgcgcaa
     5701 ggacgctcga cgcctgctgc gggcgctggg tgcttcctcg gccgcgcaca cggtcacgcg
     5761 aggatggcag ttccgtctcc tgggccccgc gactggccgt gaaaactccg gaaacgtcgt
     5821 ctccgtggca ggacaggcat gaacgcccgc gtcgaggccg gcagcctgcg accgggcagt
     5881 ggccacgttc accagcacgc gggggacgtg ttcacctgcg accggcgaca ggacttcgtg
     5941 cccaacgtga tccgtacgca ccgaggtggg cgctggcgca gggtggaccg gagtaagaac
     6001 gccggggagt gggcgaagtt cgtccatcgc tccgagatgc tcgtgttcga cgtcgacgac
     6061 ggaggggagg gcggccccgg catcgtcacg ggagtgatct cgtccaaaga agacgttgcg
     6121 gcgcgcctgg ccgcactcgc tccagtgctg gggacggccg tggccgagat cggcacggac
     6181 tgcggctgga cggcagcctg tctggagcac cttctccagg gcggccaggt ggtgacggtc
     6241 gcggacacag aacgtctcgc cgagatcgcc cggcagcgcc tgcgccccta cccgcgggtg
     6301 cgggtggtca gcgggcccgc cgccggggtc ttgggtccgg cgggttcgtt ccacgggctc
     6361 ctgtcccatc gtgcggtacg ccgcgtgccg tgggagtggg tcacccgggt tcgtccgggc
     6421 ggccgagtgt gcctgcccgt gcgtaccgct ctgggcggat ccagcacgct gctcgtcctg
     6481 accgtggcgc gggacggggc gtcggccagt ggacggttcc acgccggacc ggctccgcag
     6541 accgtgtggc ttcgcgagca ccgccctggt gagggcacct ccgtcgagtc gcagggcagc
     6601 ccgcgggcgt cggaagccct ggacgcgagg agggcgcacg tacggccggc ggccaggttg
     6661 ttcgccggtc tgcttcgccc tgaccttcgg atgcaggtcg tgcgcggcgt tgcgcagctc
     6721 gaaggcgacg ttgccgaccg cctgcgtatt catgaccacc aggcgtctcg ggcagtggtc
     6781 ttcctacact ccccccgcat ctacgagtgg gggccgcgcg atctcggctc tgatctgttc
     6841 gacgcgctcg gtcagtggca cgcggccgga gaaccagagg ttgagcaact gggcgtgacg
     6901 atcacggaga ccgaacacac actgtggctg ggtgcaccgg acggtccgtc gtggcgtctg
     6961 cccgaactcc acacgatcac cggcgaggtg gagcggcatg cgacctgacc atccgatgct
     7021 cctccacccc tccgcagcga tcgctgagtt gcaggcacgg ccgtcgagcg cccggatgca
     7081 gaactacctg ctcggcgggc gggacaacta catcgtcgac cgtgacggcg cccgtcgggc
     7141 ggccgaccgg atgccgttcc tggagagcgc cgtccgccac gagcgcaggt acgtgctcct
     7201 gatggtgcag gccctggcca tcgcgggcat ccggcagctg gtcgacttcg gctgcggcct
     7261 tccccacggc ccaacgccgg tggatgtcct gacccgcatt catcccgacg cccgcgccgt
     7321 gtgcatcgac aacgacgtgc tggtgcacac ccacgccgaa ggaatgatga cggccaaggc
     7381 gcccgctgtc gtggcgagcc tgtgcgccga cgtacgcgcc cccgaatcga tcctcgtttc
     7441 cagagaaatc ctggagacga tcaactggcg agaaccggtc atccttctcc tcggcagcgt
     7501 gctccaccac atcgaggaca ccgagacgca gcccctgacc gtcctcgtcg accaatacaa
     7561 acacgtcgcc gccaccggca gcgctctcgt catcacgcac gccaccgccg acgtctcggg
     7621 caaacccgta cgcaaattcg ccaagaccat gacggcagcc ggctgccccg tccacctgcg
     7681 gacgaaggaa cagatctccc ggctgttcga cggctggcaa ctgaccgccc cgggcctgac
     7741 cgcgccacag acactgacac tcgaataccc ggtcctgccc caggcagcct cgtacgccgg
     7801 cacggcccga aaggagaccg cgcatggccg agctgtttga tcagaagacc gacgtgatca
     7861 agccggtgac cagccaactc cccatggtgt cccggctaga atccgtggcg tccggaaacg
     7921 ggcacccggg cgtcgcggtc actgacgctg gacgtcacgt ctgcaccccg gagatccgca
     7981 tgcccaatac ccgtcccttc tcgcgcgttc ccataaaccc ctttgtgggt cggttggccg
     8041 atgccacgcc atggtgcccg gacgcgagtc ggtgtcggcc gcacccccgt ctggcaggcc
     8101 agcggtgaac aggccgacag cctcgcatcg aggcggggac gacatggcgc agcgccaccg
     8161 ggagccggtc ggcgtccatc tcatcctgcg gcgtggcggc gaggtgctgc tgagccggag
     8221 ggcgggcgac acctatgcct tgggcttgcc tggaaaccca gaatcccgac cgccacgcct
     8281 acaccttcga acggatccag gagctgcccc tggggcgctg aacagcagcc ggcttccgcc
     8341 agtcggcatc catcgccgaa ccaccctgca attggcgccg acgccggagg cgaaggcgca
     8401 cgaggccccg taaggaaccc ctctatgacc gatgtgaccg tggcccccga cgaggccacc
     8461 cggctccgca acaaggtcgt cgaccagctc aaggaggacg gcacgatcgt gtcgccggcg
     8521 gtcgaagccg ccatgcgtaa ggtgccccgg cacctagccg tgcccgaggc gccgctcagc
     8581 gacgcataca gcacgtacaa tgccgtgatc accaaggagg acgagcacgg caatcacacc
     8641 agctcggtgt ccgctccgca gatccaggcg atgcagctgg agcaggccag catccgcccg
     8701 ggcgacaacg tgctggagat cggcaccaac gggccgaacg ccgcctacct cgcggagctg
     8761 gtcgggccca ccggtcaggt caccaccgtc gacatcgacc ccgcgcccgc cgaccgagcc
     8821 aagcggttcc tcaccgagac cggctacacg ggcgtcaacg tcgtcgtcgc cgacgccgag
     8881 aacggacttc ccgggaacgc cccctacgac gcgatcgtgg tgacggtcgg cgcctgggac
     8941 atcccgcccg cctggatcga ccagctcaag gacgacggcc ggcttgtcgt gccgctgcgc
     9001 atcaacggcc tcacccgcac gtacgggttc gtccggcagg ctgaccatct cgtcgccacc
     9061 agcgcccacg tgtgcggttt cgtggcggca cagggcgcag gctcgcacac gcagcaggtc
     9121 atgcagttcc ccggagagga gggcgtcacg ctgcgcttcg acgagggctt gcccgccaac
     9181 ccgtcgctgc tggacggcgt actggacagc gcccgcgccg agacgtggac cggggtgacc
     9241 gtcgccagcc aggagcccat cggcaccctc cagatgtatc tgtccacgca ggtcccgacg
     9301 tactgcttca tgtccgccga ccctgagttg accaccggca ggatcggtcc cacgggcagc
     9361 ggctggtcca tggtcgccat cgacgggccg cacttcgcct acaccgtcgt gcgccgcgac
     9421 accgagaaga agaccgcgga gtacggggtc cacgccttcg gacccgacgc ggccgagttc
     9481 gctgagcgaa tcaccgacat cttccgcacc tggggcgaaa aggtccgcgg cagtgacggc
     9541 ccgcgcatcg ccgtctaccc ggcgggcacg cccgatgacc ggatcaccgg cgaccggatc
     9601 atcgacaaga ggcacagccg gatttcgatc tcctggccgg ccgtctgaac cgcggcgctg
     9661 ggccagggcg ttctgcacca tcccatcgga caaagagagt gatcacatga ccaccgccgt
     9721 actgcacagc gtccccgccc cggtcggcct gccggtcgac gccctcgccg acgacgactt
     9781 cgagctcgac atccgggtcg tcatctccga gagccccctc accgtcttca tgtgccccac
     9841 cagcgacggc tgcggcaaca cctgcgtgaa cggggccagc gcctgccagt cctccatcga
     9901 ggacgccgcc tgacacgcgg cgtccgccgg ggcgacagcc gatcatcgct gccgccccgg
     9961 caccccccgt ccgcgcaccc cacaacagga agggacaccg gtggcccacg gaatacccct
    10021 cacgtatcag tggcagcccg gaatgctgct gcgcgcctcc accgcttccc ggccgatccc
    10081 cgtgccggac tttgacctgc acggcgacga cgccacgatc cgcagtcggc agtggctgga
    10141 ggaggtatgg cgcgctccag tgccgacggc gctgtccgca gccagccccg tcctgtgtca
    10201 gcgcgtcgcc gagatcctga acggcaccgt caccgacggc cgccgtatca ggcgggccgt
    10261 ccggtctgtt gccgcgtacc tcctgcggtg gaaccaccgg cccaccccgt tcggggtatt
    10321 cgccggcgtc gcccccgctg agcccgctca agccgcccac attctgtggg gtgaggggta
    10381 ccggactgtt ctgcggcctg attccgactg gctgacggac gtcattaccc gcctggagag
    10441 ccaccccgct ctgctggccc ggctgacggt cgtggccaac aacaccggcc gctcccgcgg
    10501 caaccggcac gtggtggacg ggatgcctgc cgacgcgcac acctccggct acgcccccat
    10561 cgagctgtcg gtccgcctca cccggcccgt ggccgccgtg ctggaggctg cccgcacccc
    10621 gatcccgtac gagctgctcg tgcaccgtct gtccgggcag ttccccaccg cacgccccga
    10681 gcagctcgcc ggcctgatcg ccgacctatt gaacaagcac atcctgatca gcagcctgtg
    10741 gcccccgatg acgtccgtcg acacgctcgc ccacatatgc gatgagctgg agaaagcaga
    10801 cgccaccggc atacccgaca gcgcagagct ggcctcccag ctcgcttcga tccggggcgg
    10861 cttgaagcac ccggacaccg tcgccccttg gacgctcagc gacccgctga cgcagagcat
    10921 gcagcacgtg atcgccaccg gccgcgtccc gctactggtc gacgccgcac tggactgcac
    10981 cacccacatc cccgaagccc tcctggccga agccgccgag gcagcccagg tcatgcatca
    11041 gctgtcgcct catccatacg ggtatcccca atggcgcgac taccaccagc ggttcctcga
    11101 ccgatacggc agcgaggcaa tcgtgtccgt actggacttg atcgcggaca gcggcctcgg
    11161 cctgcctgcg ggcttcctgg gctccgagcg cgcccgcccg ccatatgaga tgaccgaccg
    11221 ggacgagaag atcctgcgcc tgctccagga ggcgatgctc gacgggaggc gcgagctgct
    11281 cctcacccgg gcaacgatcg ccgacctgac cgccggccac accgaaccgc tcctgcccat
    11341 gccccgggcc gagatcgccg tggagatcca cgcccccagc ctggaggccg tgcagggcgg
    11401 cgactaccgg ctgctggtca ccggcgcccc ccgccccggc agcagcatgc tcggccggtt
    11461 cgcgcacctg ctcccgccgt ccgcgcagag cgcgctcacc gactcgtacg cgaccgccgg
    11521 ccccggcgcc atcgcggcgc agctgtcgtt cacccctcgc cggcgccgca acgagaacat
    11581 cacccgcacc atgcaggtcc tgcccttcac catccctctc ggccagcacc acgagcctgg
    11641 ccccggcgtg atcccgctcg acgacctggc ggtgaccgcc gatacccgcc ggttctatct
    11701 ggtgcgcagg tcaacggggc agcacgtcga gcctcgcgtc acccatgcgc tggaagcgtc
    11761 cgtccacaca ccgccgctcg cccggttcct ggcggagatc accaccgccc gcagcgccgc
    11821 ctacagggcg ttcaccttcg gcgtcgccgc caccctgccc tacctgccac gcgtgcggta
    11881 caagcggacg atcctcgcgc ctgcccgttg gctgctgtcc gccgaggaac tgcccggccg
    11941 gtccgccccc atggccgact gggacaaggc actggcccga tggcgcgaac ggctctgcgt
    12001 ccccgatcac cttgctctgg tcgaagacgg ccagcagctg cccctcgact tcgaccagcg
    12061 catccaccgg gcgctgctac gcgccggcgt ggaccgcaac cgcgttgtcg aactacgcga
    12121 aagcaccact gcgcgggact gggcatggat cggccgcccc cacgagctcc tgatccctct
    12181 agcgaactcc acccccgccg acgcgccccg tctgccggag gccgctgccg ccgccaccgg
    12241 gacgcccagc cagcccaccg tcctgtatgc ccgtctgttc gcgcaccccc agcgctacga
    12301 cgagatcctg accggccacc tgcccactct gctcgaccag tttgacacca tgccgctctg
    12361 gtggttcagg cgccatcgcg acacaatccg cccggcctcc gaccagcatc tggatctgta
    12421 ccttcgcctc cccgatccag ccgccttcgg cgcagccgcc caacaggtca ccggctgggc
    12481 agacgccctc ggcagccaac gtctggcgag ccacctggag ttgaccacct acccgccaaa
    12541 gtccggcccg tatgggcatg gctccgctct ggacgccgcg cacctggtgt tcgccgcgga
    12601 ctccgccgcc ggcgtggcgc agatccgtgc cgctgcggat gacgccgcca tcgggcaggc
    12661 cctgaccgct gcgagcatgt tcgacctgac ggtgcggttc accggcgacg cagatcaggc
    12721 gtcggactgg ctgatccgcg ccctgcctca agaacacggc cctctcgccc gggagcgcgt
    12781 cacgctggcc ctggctctgg ccgatcccga gcacgctgtc ctccaagccc tgccgggcgg
    12841 ccccgatgtc atcgccgcct gggggcagcg cgctgccgcc ctgaccgcct accggcagca
    12901 gctgtccacc gagcgcaacg ccgacagcgt gctgcggtcg ctgctgcacg agcactgtgt
    12961 gcgggcgctg cccgtcgccc ccgatcacga acgcgccacc ggccggctcg cccgggcctg
    13021 tgccctgcga caccgggagc ggcagccgtg accaccgcaa caaccagccc agccgtgctg
    13081 gcggagacct tcgcccgcca cctggccacc ccggtcccgc cgcccgaaga ccagccctgg
    13141 gcggcgcagg acctagccgc cggcgctgcg ggatccgcgc tcctgcacat cgagcgcgcc
    13201 cgtaccgggg acggcacctg gcagcaggca cacccctgga tcaagaccgc cgtcgccacc
    13261 cccgtcagcg ccgccgacac cagcggcctg tacctggggg cgcctgcggc ggcgttcatg
    13321 ctcgaatgcg ccgtcaccgc cgaggcaccc cggtatcagg acgcgctggc agccctggac
    13381 caccatgtgg ctcaactcgc ccaccgcaga tgcgacgcag cgcaaactcg catccgccaa
    13441 ggccgtccag ccggcttcca cgagtacgac atcttctacg ggctcaccgg catcggcgcc
    13501 tacctgctgc gccggtcccc gtccggcacc gcgatggcac gcgtcctggc ctacctcgta
    13561 cagctcaccc gccccatccg ccacggcgac caggggatgc tgcccggctg gtgggtcgat
    13621 caccagcccg acctcacccc gtccaccgtc cccgccggcc acgccaactt cggagccgcc
    13681 cacggcatca ccggcccgct gctgctcctt gcccgcgccc tgcgccaaga cgtgaaggtc
    13741 gacagccagg aagacgccat cgacaccatc cttcactggc tcgatacgtg gcggcaggac
    13801 ggacccgccg gattctggtg gcccgagcac ctccgcctcg gtgaactccg caccggccgt
    13861 ccctcccaac gcggcccggc acggcccagc tggtgctacg gcgcccccgg catcgcccgc
    13921 gccggacagc tcgccgccct cgcccgccgc gacccggctc gccagcgcct gtacgaggac
    13981 gccctggtcc gctgcctgac cgatcccgat cagctgtcca agatcaccga cgccggcctg
    14041 tgccacggct gggcgggcgt ctaccagacc gccttccgcg ccgcccacga cgccgccacc
    14101 ccggccctgc gcgccaccct gcccgacctg gccgccgccc tgacccggca cacccaaccc
    14161 ggccacgacc ccggcctcct gcaaggcgcc gcgggcaccg ccctcgccct gaccaccgcg
    14221 gcccacgacg ctgcgccgac ctcgggatgg gacacatgcc tactgatcga ctgaaccaac
    14281 cctccctcct ggaagcgact ctgcacgccg tgctggacgt cctggccggc accgacacgg
    14341 acaccgccgc agcccgcgcc ggactcgagc ccgccgacct ggacgccgcc gtcgccgtct
    14401 atcagcaggc cgggcaacag gccctcgccc agcagtcagg gcccctggca tggcgtcagc
    14461 tgttcatccg gttcaccgac tggggcaagg ccgagcagac cgccgccgag tacatcgccc
    14521 ccgtccttga tctggcccag caggacgctc tgatcaacgg gtggtggttc atccgtaagc
    14581 acccgtgctg gcggatgcgg ctgctcccgg ccgtcgggac acagctcccc ccggcactgg
    14641 ccgacacgct cgacgaactc acggctgctg ggcgagtcca ccgctggtgg cccggcatct
    14701 acgagcccga aaccgcagcg ttcggcggcg acaccagcat gaccatcgcc cacaccctgt
    14761 tccacgccga cagccacgcc atcctcacca caactcatgg cgagctgggc cgccgagagt
    14821 tgtcactgct gctgtgcgcc accctgatgc gcgccgccgg actggagtgg tacgagcaag
    14881 gagacgtctg gcatcgcgtc acccgggaac ggcccctcct ctcagacgta ccggccgcca
    14941 aagtccacgc catggccgac agcctccgac agctgctcat cgccgatacc agcgcttctg
    15001 gccccatgct ccactcggac cgcactctca agcccgccac cgactgggtg agtgcgtttc
    15061 ggcaggccgg aggagacctc ggcacagccg cccgggacgg agccctcgac cgcggcctgc
    15121 gcgaggtcat ctcctaccac gtgatcttcc actggaaccg gatcggcctg tccgcccgca
    15181 cccagagcgt tctcgctcac gcggcacgta ccgcgatcct gcatcccgct gaccccacgg
    15241 aaaggccgat gctgtgaccc cgccaccaca ccattcacag gcaaggatcc gtcggctctc
    15301 caggcgcttc cccctggtca gccggtccca cctcgtctac cccagcttcg ccgcacggat
    15361 cgacgaagtc cgcacctgcg gggagaagtc ggcgcaggac ggacccctcg ttgaccggat
    15421 caacctcgca tgcgccacct ggaacctgtc cgcactgatc gcctccgact gcgggctgac
    15481 caacctggcg acagacctct gcctgcgtca gctccgtctc ttccaggcag catggcccgt
    15541 caccgaggac accgccatcg ccagcctcca gcccatcgtc aacctcgtac gactgaccgc
    15601 ccgaacgggc gacccgcagg cggcctatca gcagctcatg aacgtgcacc gcgccgcgca
    15661 tgacggcggc accgtgaccg tccacgggca gaccatcgac ctgaccggct tcaccaccga
    15721 agccaccttg gaccacatcc ggccctggct ccacgacctc ctgctcgacg acggaacccg
    15781 gctcctggtc gccgccggcc actggcgtca agcggcagag cacgcgaccg cctacgacaa
    15841 ggaacccgag cggctgtacg gcagcaggca agcacacgtc gtggcgagcc tgcatacgga
    15901 cgcccaggac atgaccaact ttctgatcga caaggccacc atcaccgaac cgtgggagga
    15961 agccgtcgcg cagatcctcc gccactacgc cgaccgcctt gcgtgccgcg ccacagcaaa
    16021 ggggttcgcc gctacggcac tcgccgtgcg ggatgcgctg gaaccggccc cgccgcatct
    16081 acgcatgttc cgggtgcggc tggctctggc ggcgatcgac ctggtaccgg aaggctgcga
    16141 aatcctcgca cgtcccctgt acgacgcgat cgtcagcgac accacacagg cgtgcgacgc
    16201 gtacgcggca cgcgaaatcc tccgccaccc cgccccaccg gccgaacagc ggtcacgcca
    16261 cgaactggag gcgatcgtcc acgacagcgg cctcggccgg ggcacgctgc cggaaccggt
    16321 gctgtccacg atgatgcggg ctgtcagcac ggctggggcg aacctcgccc agtgcctcac
    16381 tcaggattga agaggaattt cagcccgggt gaccagcatc accgatcagg cagaacaacg
    16441 ttattttccg ttctgggagc caacctcctt gtgcaccatg tatttttcac aggcttctga
    16501 cctgagagca tcgattattt ccctggttta cctgtaaaat caacgaaggc cggaaacggt
    16561 cacccgggcg tcgcggacat gacgcgagac gacaagtctg cgcccccgga ggacatcgtg
    16621 cccgccccgt ttctcgccgt agccggcatg gcggcctatc taggccgcgc ctggaccaat
    16681 gcggtcacca gctgcgcagg cgcgccatcc ttcaggcgcg ctgacgcctc aagtcccgca
    16741 gctgcgaagg tcatcgccgc cgacctgctt ggtaatacgg ggccccgcgg acgtaatcgc
    16801 ccagcagaaa cccgattccg tgagcgtcac tttctctttg ggtgttgtgc tggccgtcgc
    16861 ggtgtggctg ctgatccgca aaggcggtct caaggtcggc cacgcaatag cggccgtgct
    16921 cctcggcttc tatctccgcg acagctcgct cgctccgtcc atcagccgcg gtgtgcagag
    16981 tgtggccgag atgctcagcg ggatccgtat atagaccggg cgtcggggca cccctgtggg
    17041 cccgggccgt acgccgcctc ccccgtcggc tgcagtctgg cgcgcgtgcc ccggcggcca
    17101 ctcccccatg cccggcattc cctcctccct gtcaggacca cgttccgcga ggtcacccat
    17161 gtctgatctg ccatgcccgc gaccagtcgg tcaccgacgt ggccagcgcc ggcgtgcgcg
    17221 cggcgctgag ccgctacgca ccgagaaggg gctgcgcctg cggttgaggc ttctggtgct
    17281 tgtgccctcc ttcttggtca cggcgatcgt gtgtatggcg gtggccgtcg gcacgacggc
    17341 acgcgtccat gtggatggct ggatcatcgg agcggtggtg gcagccgctg gcctgggcgt
    17401 gctggtcggc gcggactggc tggccgtgcg cacggcggct gagctgcacc ggcagcgcag
    17461 cgagtacagc gattccgtgc atggctggct gcggcacttc cagtccggtg tggacgaagg
    17521 ccgcaagagc atcagcgccg ctgttgagca gctcaaccgg ggtgagcggc ctactcctcc
    17581 cgccttcagc gcgggacagg cgggctctgg cagcaatccg tggagcgacg cggaggtcgc
    17641 tctttaccag ttgcacgcgg aggcatggcg ggcggtggtg aacgggcggc aggcggagct
    17701 gccgcaagcg ctcgtctata tcgccggggg catgaccctg ttgctcgtgc gcgcgttggg
    17761 catcgtgacc gagctgacca atcaggtcca ggacccggac ctgctgtacc gcgtgtacga
    17821 cgtcaacaat ctgctcaagc ggatgcggcg gtcggccgga cgcctcgcgg ttctgggtgg
    17881 cgtgaaggcg cgcacgctgc accagccgct cgggctggtg cagttgctgc gtggcgcatc
    17941 cggcgagatc gagaagtacg cccgggttcg catgcatacg tccaccctgg atgtgcagat
    18001 accgggcttc gccggacccg atctgatcca tctgctggcc gagttggagg agaacgccac
    18061 cctctgctcg ccgccggaca gcaaggtcgt ggtgcgcacg tcgagggtca ccgcgggtct
    18121 ggctgtggag atcgaggacc ggggcatcgg catggcccag ggcgaactcg accgctacaa
    18181 ccggatgctc gccgatcccc gggacaggga cctggccgag cagctggccc agcgccagac
    18241 cggcctgctc gtggtggcca aactcgcccg ccggtacggc atccacgtgc agctgcagaa
    18301 gaatctcatg cacggcacga cagcactggt ggtggtgccg gacaagctcc tgctctgggc
    18361 gggcgagtcg gcgcccgtat cccatgctga gcctgccgca gacgttgccg cggtaccggg
    18421 cccgtcggcg ctgtccgcgg gacgccccgg cccccggccg gccggcgggc cgaggcccag
    18481 tcccccggcc ccggtaggga cggcgtcatt gccctcccgt aacgcccggc gcgccccggc
    18541 tcagcaaccc gccgcttcgg caacgaccag ggcaacgcct tcccggggag cagcacctgg
    18601 ctctcgcccc cggttgccgc agcggacgcc acaggcaacg gtccatgagc gtgcggcccc
    18661 tgcggagcct gaggccactc ccgtcccgct cgcgccgccg gatccatcct tcgtcagcaa
    18721 gttcgcccag ggcgtgcatc gcgcggaaca agccgcggca ggccgcgagg cacgaccgcc
    18781 cgaggcgagc gcgggctgac ccccgcagcg cgccccaccc atctttcgtg ccgggtttcg
    18841 cgcctgagca ccagtccgta cgacgtacgg agatacggag aattgcgatg acgatgacca
    18901 ccgactccac ggcagcccag ccggaccggg ttgtggacga gctcctcaac gacctcgcca
    18961 aggtgcccga cgtgacgggc gtcttgctcg gctcgcagga cggcctgcgg ctggcttatg
    19021 cgggaccggg tatggacggc cagatggttg accgcctggc cgcggtgatc aacggcctgt
    19081 actcgatcgc tcacggagtc gacgacggcg agggccgtgt cgaacaggtc ctgatcagga
    19141 agaccaactt cctgctgttc atcatgagcg ccgggagccc gccggccgcg gtggccctga
    19201 acgcgggccg cgacccggac aaggtcgaaa gcgtcctggg ggtgctgacc aacacccggg
    19261 cggacgaggg aaccgtcggt ttcgcgatgg ccaacatgat caagcggatg ggcgagctgc
    19321 tggccacacc agcgcgcgcg ggcggggccc cttccggtga cggccagtga gatggcgtcc
    19381 gcaagcagcc cggcctggac cgtcgaggac accgaggccc ccagcctcta cgtcctgacc
    19441 ggcggccaga ccaggcccac acacgaccta cagatcgaga cgctgctgtg ggccgaggga
    19501 gaaccgccct ccggccagcc gccggaagcc gaccaggcca tggcgttgtg ccgggagcag
    19561 cccctggccg tcgctgagat cagcgccctg atcgggttgc ccttccagat caccaggatc
    19621 ctcatgtccc ggctgatcga catcggtgca ctcagcgccg tgaccacccc gcactccgcc
    19681 gaccttcccg acgtcgctct cctgaaggcc cttcgcaatg gactcctcaa gctctgaccc
    19741 ccggccggca cgccggttcg gccgcgcgaa gcccaccccc gtcaagatcg tcgtctccgg
    19801 cgggttcggg gtcggcaaaa ccacgtttgt gagcgccgtc tccgaaatca ccccgctacg
    19861 caccgaggcc gtgatcacca gggtctccga gggcgtggac gacctcagcc tgctggtcga
    19921 caagacggcg accaccgtcg gcatggactt cggccggatc accttccctc agctgaacgc
    19981 ggtcgtgatg ctgttcggca ccccggggca gacccggttc tggttcatgt gggacgagct
    20041 cacgcgagga gccctcgccg cggtggtcct cgtcgacacc cgccgcctcg acgaaagctt
    20101 tcccgcggtc gactacttcg agcggctcgg cctgcccttc ctggtcgctg tgaacgtgtt
    20161 cgacgacgcc agccactacg accccgacga agtcgcctcc gccctggcgc tgccgtccac
    20221 ggttccggtc gtgctgtgcg atgcccgtct gagcacggac gcgaccggcg tactcgcccg
    20281 tctcatcgac cacgtgctca cccactcgta ttctcctgcc gccgttctcc agggagcaca
    20341 gctgtgaacc cccacgctcc gtccgatctc ctgtccacca ccaggcacga caccgactgg
    20401 cagagccacc tgcccgaggt cttcgacccc atggctccgc ccgtggaggc gttcgacgcc
    20461 ttcgcccggc aggtcgccga cgtgctcggc actccctacg ccatgctcaa ctgggtcggc
    20521 gacgaacagt acttcctcgg tctcgccaat cccgccgaca gcgaactgcc cgtgctgggc
    20581 cgcaccctgc cgctgaccca cggcttctgc ccgcacgtcg tccagcgccg gggctcgctg
    20641 gttctgaccg acgtcctcga tttcgatgcc ttcgccggca acccggtcgt cgacgaactc
    20701 ggggtccgca tgtacgcagg agcccccctc atcgacaagc gtacgaacca cgtctggggc
    20761 accgtctgcg ggatcgacat cgagccgcgc gctcgctcgc aaggccgccc ggtgtggacg
    20821 cgcatcgacc acatgcgcga cctgctcatg accgagctct acctccgtac cagcccgtag
    20881 caggacccgc gcccagcagc accgttcgcg accaccaccc caagggggag accacgatgc
    20941 ccacgatgtc gtccacgact gcggatctca cgcccgacta cgaagccctg gtccagcact
    21001 tcgacgagtt cgccaccgcg gaagtcgccc cccgagtcca gcgcatggag tcctcccccc
    21061 acgccgtgga acgcgacctg gccctgctca tggccgaaca gggatggttc ggcgccacga
    21121 tcccccgcca gtacggcggt atgcacgcgg gacatctcgc caaaaccctc atgatccaga
    21181 ggatggcgcg ggcctcgggc gcggccggcg ccatcctgca ggccagccag ctgcccgtat
    21241 cgatgctcat ccacttcggc agcgacgagc agaaggccct gctgctgccc caggtctcct
    21301 gcggggacac gctgctgtcg atcgcggtga ccgaagagga gaccggcagc catgtgctcg
    21361 gcatggagac caccgcccgc cgcgacggca acgactggat cctcgacggc agcaaggtcc
    21421 acatcggcaa cagccacatc gcccacttcc actgcgtcgt ggcccgcacc gcctccgccg
    21481 acacggccgg ctcccgcgcc ctgaccgcgt tcctcgtcga acacgaccgc gacggactga
    21541 ccgtcgaacc gcaccggccc gccctcggcc tgcacggctt caccttcggc aagctcacct
    21601 tcgacggcgt acgcataccc gaggccaacg tgatcggcga agtaggcgac ggcaaagaca
    21661 tcgcctacag cagcagcatc ctctacggcc ggcccaacct cgccgcggtc tccctcggca
    21721 tccacgaagc gatcatggaa tgcgcggccg gcttccttca gggccgccgc cgctacaacg
    21781 gcgccctcgc cgaccttccc gtcctgcgcg accgggtcgg cgacatgaag tcccggctca
    21841 tggcgagccg cgacctcgcc caccacgccg tacgcatgct cgactccggc cgcccctgcg
    21901 acgacctcct catcaactcc aagtacctca accacaaatg ggccgtgcaa tcgggccagg
    21961 acgccatgga actgcacggc gcccacgccc tgcgcacgga ctaccccctc caacggctgt
    22021 ggcgggacgt ccagcacacc tacgcgcccg ccggaaccgg tgaggtacag cgccagcgcc
    22081 tggcggaaac cgagctcggt gcccctccca tccagtggtc cgaacggctc gccgccaaaa
    22141 cctcgctctt cctccccacc agcacagccg cctgactccc agacacccac gccctccaac
    22201 acaacaacca gctgcgggaa ctcccgcccg caatgtcttc ctccgggacc caccgtccgc
    22261 ctccaggccc cacccgccac gtggggcctg ccaaccgcgc ggccggtccc ggtgcccgcc
    22321 accagccgcc tccctgtccg ttccgccgaa agccagttga tgaagagccg agcgcccctg
    22381 tctcccctgt tgtggtggca gcccaaagcc cgcaccgggc atggattccc aggacacctc
    22441 cacctcagcg ccgcaccgag cagcaacctc gtggtcacac gcgccgccgt cccaatctgc
    22501 ccacagcccg gccaggtacc gatcacggtc agggggacgg gggtgtgacg atcatcgacg
    22561 tccccaatga gacacggggc cactccgggc tcgccgagga aatcgagcag atcctgcggg
    22621 acaccgcgtc tttgatccag gaggtcacgg acctgtcctg cccgacgctg gtgttccggc
    22681 tgctcactcc ccgcgcctgg agggccgaga tccgggcatg ggccgagcgg tcgctggagg
    22741 aagaccttgc acaggcccgc ctcaccgcgc cggaagccga ccgggtgcgc ggccggctca
    22801 cggcatggga cgccagcgac ctgcgcccgg gctggccgat gaaccccggc ctgacgatca
    22861 ccgaccacta cggcgaaccc cgcacgctga tcacaccgca ggccctgcac cacacggggg
    22921 tccgctacga ccgcaccgcg ctgatccgct tcgtcgtcca cgccggtgtc caccacgctc
    22981 agatcgcagc aagcacaggc acgctccccc cgcccccgat ccgtgctgct gcccgcgtgc
    23041 acgaggactc ggccacgagg accctgatgg aggggcatgc cacctgggcc gaacagaaag
    23101 tggcaggcgc ctacttcgga ttctgccggg agcaccggcc ccgagaagtg ccgcgctcat
    23161 ggcggtaccg gcagcatgcc cgactgatcc cctggttgca gccccctgcg gatctcacct
    23221 cgctgatgtg cgcgcgagca gcggatccga gtccaccggc ccgcgaagac ggcgcgagtt
    23281 ttgtccaggc agtcatcgaa gtctccggca gcgtcgcccc gttcaaccgg atctggaccg
    23341 acccctcgct cgcccccacg aaccgggaaa tcacccatcc cgaggcatgg ttcagccgcg
    23401 tcagcatcga aggaccagcg ctcctgtaac cgccgccgcg ctgaggagcc tccgctccca
    23461 ctcccccggc cgggcccctc tcggcctcag tcccgcgtaa cgccattccc ataccgacca
    23521 caccagcacg aaaggatcat cagtgacccg gttgaccgcc tcggacacac cccgtcgttc
    23581 cgccccgcgg aagcttccct cgatgcgtcc gtatcagaag gaggtgcacg acgcggttgt
    23641 caccgggctg acgaacggga cccggggaca actgcacgcg gcgtgcgggt ccggcaaaac
    23701 cttcatggcg ctgcgtgcgg tggaggaact ggtcccggga gacgggatga tcgtggtcct
    23761 ggccccgtca ctggctctgg tcgcgcagat cttgcgggag tggcaggacg ccggcgtggt
    23821 cgggttccgt gcgatggcgg tctgctcgga cgagaaggtc tccgacgtcc cggtacggac
    23881 cgaggatttc gaggtgccgg tcagtactga tccggacgtg atcacctcct ggttgagcgg
    23941 tggcaggcgc cggatcatct tcggcaccta cgcatctgcc gcccggatcg gtgaaagtct
    24001 gcggcaggcc ggtctcgaag tcgacatgct ggtgtgcgac gaggggcacc acctgttcgg
    24061 caaacgggat gccgcccgtc gtcgggtcgt caccgactcg gctttcctgc cccaccgcag
    24121 ccgactggtg atgacggcaa cgccgaacgt gacaggcggc caggccgggg atgcgttgac
    24181 ctggcagagc gaggaactgt tcgggccggt gctgtaccgg taccccttcg cccgcgggat
    24241 cgccgagggg tatctgaagg actaccggct ggtggtgctg ggcatcagcg acgccgaggc
    24301 ccgtgccctg ctcgccgaca ccgcatccga ctacgtagac ggcgagatcg ctctgaggac
    24361 cgtcgtcgcg caggccgcgc tggcacacgc ccgcaacacc tacggcaccg agcgcgccat
    24421 caccttccac ccccgggtgc agcaggccgc cgacttcgca cgcacccttc ccgccaccat
    24481 cgcccgcctg cccgccgcca agcagccggc gggcatggtc cacgctaccc acatcagcgg
    24541 ggcgatggac accgccgagc gggagggcat catggcgcgg ctggcgcagc cgcccgccgg
    24601 cggatggacg gtggtctcca acgcgcagtg cctgaccgag ggcgttgatg ttccggcggt
    24661 ggacacgatc gtcttcaccc acccgtcccg gtccgcggcc aaggtgaccc aggccgtggg
    24721 ccgggccatg cgccgaagcc gccacacagc ctccatcgcc acgatcatcg tgccggtcat
    24781 cgttccggac accaccgccg aggtcgacga cgaactcgac gccggcgact tcgaagctct
    24841 cttcgaagtc gtacgtgccc tcagggccca cgacgacgtc ttcggcgccg aactggaccg
    24901 ggaacgcgcg aacttgtcgc tgcgcaccgc cggcaggaag ggcgccgagg gacccggagc
    24961 gcaggaaggg gaggaatccg acctaccgaa gaggatcacc ttccacctgc cggagggcac
    25021 atccgaccgt atcctccatc agctgcgtct gctaacggta cgcaactcca cctcctcctg
    25081 gtgggaggga tacgcggacg cggtcgcctt ccacaaggag cacggccacc tgaacgtgcc
    25141 ggagaaccag ctcggcgcca gtggccgcca gctgaccgca tggatagcca ccttgcgcag
    25201 gcatcgccgc aaggggtggg ttccccagga ccgtatcgac gccatggacc gcatcgg
//
