LOCUS       NZ_CP044545            21875 bp    DNA     circular CON 16-NOV-2023
DEFINITION  Pradoshia sp. D12 chromosome, complete genome.
ACCESSION   NZ_CP044545
VERSION     NZ_CP044545.1
KEYWORDS    RefSeq.
SOURCE      Pradoshia sp. D12
  ORGANISM  Pradoshia sp. D12
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Pradoshia.
REFERENCE   1  (bases 1 to 3934149)
  AUTHORS   Meng,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (03-OCT-2019) National Institute for Communicable Disease
            Control and Prevetion, China CDC, CHANGBAI Road No. 155, Beijing
            102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. Jun-2019
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 237.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/16/2023 02:43:39
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 3,855
            CDSs (total)                      :: 3,730
            Genes (coding)                    :: 3,692
            CDSs (with protein)               :: 3,692
            Genes (RNA)                       :: 125
            rRNAs                             :: 10, 9, 9 (5S, 16S, 23S)
            complete rRNAs                    :: 10, 9, 9 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 38
            CDSs (without protein)            :: 38
            Pseudo Genes (ambiguous residues) :: 0 of 38
            Pseudo Genes (frameshifted)       :: 16 of 38
            Pseudo Genes (incomplete)         :: 21 of 38
            Pseudo Genes (internal stop)      :: 10 of 38
            Pseudo Genes (multiple problems)  :: 8 of 38
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:28:11
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2015623
            Orig. end                         :: 2037498
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044545.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria and source DNA available from Jianguo Xu.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21875
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21875
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21875
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11875](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11875)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(676..2094)
                     /gene="uxaC"
                     /locus_tag="F7984_RS09710"
                     /old_locus_tag="F7984_09710"
     CDS             complement(676..2094)
                     /EC_number="5.3.1.12"
                     /GO_function="GO:0008880 - glucuronate isomerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006064 - glucuronate catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="uxaC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019720201.1"
                     /locus_tag="F7984_RS09710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09710"
                     /product="glucuronate isomerase"
                     /protein_id="WP_066103668.1"
                     /transl_table=11
                     /translation="MSSFIHENFILQNETAVKLYHEYAKNMPIYDYHCHLSPKDIAENR
                     KFKNITELWLEGDHYKWRAMRAHGIPEKYVTGDADPKEKFEAWAKTVPYTVGNALYHWT
                     HIELKNYFGIEELLNEQTWESIWNRCNELLQQDDFSVRELIKRSNVKVIGTTDDPTDDL
                     MYHAQIAELPDFPVKVLPSFRPDKGLEINKATFVPFVETLEKVADKSLATYADYIAALL
                     DRVQYFHEKGCRISDHGLSEVPFAEFDESELDGIYQSGRSGKAVSLEDENKFKTAIMIA
                     LAKAYTERGWAMQLHFGAIRNNNTKMFKRLGPDAGFDSISDQGEVAAPLNALLDALEIR
                     DSLPRTIVYNLNPVYNELIGTTIQNFQTNEEGIAGKIQFGSGWWFNDTKPGMIRQMTAL
                     ADQGLLSHFVGMLTDSRSFISYSRHEYFRRILCNLIGTWVESGEIPNDPALLQNLIENI
                     CFNNAKNYFNIDLQ"
     misc_feature    2052..2064
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 22.66"
                     /tool="antismash"
     misc_feature    complement(2071..2086)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            complement(2128..2772)
                     /locus_tag="F7984_RS09715"
                     /old_locus_tag="F7984_09715"
     CDS             complement(2128..2772)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017471355.1"
                     /locus_tag="F7984_RS09715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09715"
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="WP_066103666.1"
                     /transl_table=11
                     /translation="MLPKFEVLNEMRKGYVVAVVRGKTKEEAVEIAKQAYAGGIRSLEI
                     TFTTPDAGDVIAELASMNDDNMIIGAGTVLDEATARLAIMKGARYIVSPHFDKNISLMC
                     NRYCVPYLPGCGSVTEVMEAVTYGSDVIKMFPGSLLGKSFIKDVHGPLPHVQMMPSGGV
                     SKDNLADWIEVGAFAVGIGSALTKNVKDGDYSSVQAVAREFMDHLATLQNK"
     gene            complement(2861..3721)
                     /locus_tag="F7984_RS09720"
                     /old_locus_tag="F7984_09720"
     CDS             complement(2861..3721)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013400975.1"
                     /locus_tag="F7984_RS09720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09720"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_066103664.1"
                     /transl_table=11
                     /translation="MTTLPFKVDLTDKVAVVTGGAGILCGAFVDALAACGAKVAILDRA
                     LENAEKKAEEVRQKGGIAIGVEANVLDKESLKAAHAVVKEKLGLCDILINGAGGNHPLG
                     TTTKEYLFPEDLNGQLKDTITFFDLDPEGVQFVFNLNFLGTLLPSQEFASDMVNRKGAT
                     IINVSSMNAYTPLTKIPAYSGAKAAVSNFTQWLAVHMSKVGIRVNAIAPGFFVTAQNEK
                     LLKNEDGSYTERSEKILRNTPMDRFGEAEELVGTMLYLASHEASSFVNGVIIPVDGAFS
                     AYSGV"
     gene            complement(4006..5415)
                     /locus_tag="F7984_RS09725"
                     /old_locus_tag="F7984_09725"
     CDS             complement(4006..5415)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010677887.1"
                     /locus_tag="F7984_RS09725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09725"
                     /product="MFS transporter"
                     /protein_id="WP_066103662.1"
                     /transl_table=11
                     /translation="MSAEALKKQGSPKENPTPNVRPFGMRDKIGYLLGDFGNDFFFLLV
                     SAYLMVFYTDIFGINAATVGALFMAARLWDAVADVTWGRFIDTRKPTKNGKFRPWVLRM
                     SFPLVFSGVLMFVTIPGMGDGFYLAWAFVTYIVWGTLYSTVNIPYGSMASVMTDNPVER
                     TSLSTYRTAGMMLASLIINAVGPMIVFVDNKIDANRMFMAACIFGVLAISCYIGCYKLT
                     TERIVPETNDAEKMDLRKTLKAIGQNKPLIWILTASLLFMTNSMLMGAVNVYLFKDYFT
                     STAALSLVGVMTTVTAFIAMPLVKPLVARFGKKEIASIGMGFAAIIYFVLFMLKDIDAM
                     TFVWIAALGMFGTAFLNVVIWAFVTDVIDYHEFLTGLREDATIYSVYSFARKVGQAVAG
                     GLGGFLIAAVGYNAALETQTEGTLNGIHALGTLAPALFYAVIFLILMFLYPLNKKRTEQ
                     LAIDIAERRKK"
     misc_feature    complement(5743..5754)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     misc_feature    5749..5764
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 23.71"
                     /tool="antismash"
     gene            6214..6603
                     /locus_tag="F7984_RS09730"
                     /old_locus_tag="F7984_09730"
     CDS             6214..6603
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF002460.0"
                     /locus_tag="F7984_RS09730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09730"
                     /product="CidA/LrgA family holin-like protein"
                     /protein_id="WP_140461493.1"
                     /transl_table=11
                     /translation="MKYLVICSQILVLFLFYYIGVFIQELLSIPVPASIIGLLLLLVCL
                     KFKVIPVEYINRGAGFLIAFLPLLFVPICIGVIKYPELFSSKGFIIMFVVFISTIFTLL
                     ISGGTSQILENSVNKRKDQNKWGNY"
     gene            6588..7280
                     /locus_tag="F7984_RS09735"
                     /old_locus_tag="F7984_09735"
     CDS             6588..7280
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018393554.1"
                     /locus_tag="F7984_RS09735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09735"
                     /product="LrgB family protein"
                     /protein_id="WP_140461494.1"
                     /transl_table=11
                     /translation="MGKLLIAISIIIITVIIFLLLNKLYIRFSNPFLLPILTTTILIVC
                     ILSVFNISYDTYMIGGEWINQLLGPAVVALAFPLYKQWRMLKDHIFVILGGVFLGVLAG
                     MVSGLLFSKLAGVAEETAVSILPKSLTTPVAVQISEELGGVPALTAIFVMIAGLTGAIL
                     GPLILNLFHITNPVSKGIALGSASHAIGTSKAFEFGELTFSMSSISMTLSAVFGSIVGP
                     IIMNLLIN"
     gene            complement(7317..8867)
                     /locus_tag="F7984_RS09740"
                     /old_locus_tag="F7984_09740"
     CDS             complement(7317..8867)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7984_RS09740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7984_09740"
                     /product="hypothetical protein"
                     /protein_id="WP_140461495.1"
                     /transl_table=11
                     /translation="MDGTLLSNSIYSLKGADLRIIYSLLTNLNLKELIPFNFNKIISRK
                     HNTDYVNCLLEKTDEYIHLSDEALQVSLFQEMNKTLELEGVYYSEAFHVDNQCEEIVEK
                     VYQIYINQEKSFLQNTEQIEFTRIHHIIHYQLRQLFYEVEYRFQNLSVEDQQDFLNTIY
                     EFIIQLSEDEKWILLQQLPANYLSIEVFKEIELSTLLIQVSNISLPSFFDMFTKLLMNY
                     NEKLPMNIPLINQENISPTTKLLTSPYFITPYVLGGRVLQINYQHHAIKKRLMPFILMQ
                     ITLAYLCDENSVSSPVLFLNEWKRRVEEYRQLEYHSDLLEMKHIEMSSSVHKSRQRINE
                     FANQKKHIQERLNIEMYKLKSTLLFMDINELTINQSFEKHRTEYIHIQKKLNQLAASKS
                     NEILETSLIKQFTNKLLNMSVTLDQLGKEKKVDELLESLVRDILDSDSDFKRADRIGIK
                     QIQKELTDIDFMIETENKIKSKYEKELIKLNQQLQECSDKVKQIENENYGIKEVAQSI"
     misc_feature    8939..8953
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 22.14"
                     /tool="antismash"
     gene            complement(8956..9108)
                     /locus_tag="F7984_RS19060"
     CDS             complement(8956..9108)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7984_RS19060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_192796796.1"
                     /transl_table=11
                     /translation="MMKFTRNENNAASILPFRDMDAVFYAVIIHGVVKPFFVPLFMNYT
                     FINLN"
     gene            complement(9092..9907)
                     /gene="proC"
                     /locus_tag="F7984_RS09745"
                     /old_locus_tag="F7984_09745"
     CDS             complement(9092..9907)
                     /EC_number="1.5.1.2"
                     /GO_function="GO:0004735 - pyrroline-5-carboxylate
                     reductase activity [Evidence IEA]"
                     /GO_process="GO:0006561 - proline biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="proC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006836351.1"
                     /locus_tag="F7984_RS09745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09745"
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="WP_139891893.1"
                     /transl_table=11
                     /translation="MNKRIGFIGCGNMGKAMVGSLINSNQKLADQLLVSVRSEESKVAI
                     SEKWPIHTTLDNKEVVLNSDIIFLAVNPNQYEEVIKEIREYVTDKKILISIAAGVKIKQ
                     MDEWIGAESKFILSMPNTPVLVNAGMTAICPNDHVTGEELEEICQLFSVFGEYEILKED
                     DFEAFIALCGSSPAYIFVLIEAMADAAVKLGIDRKKAYRMAEQTIMGSAKLALETGIHP
                     AELKDQVCSPGGATIAAITELEAQGFRSSVIKAMEVCAEQSKKMNDEVY"
     gene            complement(10001..11875)
                     /gene="shc"
                     /locus_tag="F7984_RS09750"
                     /old_locus_tag="F7984_09750"
     CDS             complement(10001..11875)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR01507.1"
                     /locus_tag="F7984_RS09750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09750"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_140461496.1"
                     /sec_met_domain="T2TS (E-value: 8.9e-105, bitscore: 349.0,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKSNVEKYIASKLERLEKTQNQSGSWTFNFEGSSLTDCFMILLI
                     RTLGIDEEELMHQLVKRLLRTQNDNGSWSIYPDEKDGNLSATVQSYTALLVSGKFTRMD
                     EEMKRAEQFIIKHGGVSKSHFMTKMMLAVNGMYNYPSFFKFPMSYFMLPPHVPFNMYQC
                     SNYARVHLTPMTICINKRFMYEHKGIDKSFLDGQEGGWFREERFFQTEQLINQLKILNF
                     SPSSWQKAGYQSAEKLMIDRVEKNGTLYSYSSATCYMIYALLALGYKRNSPIILKAMEG
                     MKSYLTDTPYGLHLQNSPSLVWDTALLSYSLQEAGVKATHPVIDRANAYLLKKQQSTRG
                     DWTVHAPDVIPGGWGFSDSNHYIPDNDDTSAVLRALTKQSKLNQQANLAWKKGFSYLKG
                     MQNKDGGWGAFEKDAYNSLFAYLPIENAKDAIIDDSTSDLTGRVLEFMGNYAGLTHDHS
                     FIKRAAAWLLKEQLSDGSWYGKWGVCYIYGTWAAVTGLCAIGIKPEHPSIQKAIRWLES
                     IQLKDGGWGESCMSADKERYIPLSYSTPSQTAWALDALLAVKRATSPTIQKGVNFLINE
                     ELYHPNANRYPTGLGLRGGFYIIYESYNYIFPLLALGHYEKKLITDHT"
     gene            complement(11899..12936)
                     /locus_tag="F7984_RS09755"
                     /old_locus_tag="F7984_09755"
     CDS             complement(11899..12936)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012512.3"
                     /locus_tag="F7984_RS09755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09755"
                     /product="pyridoxal-phosphate dependent enzyme"
                     /protein_id="WP_066103649.1"
                     /sec_met_domain="PALP (E-value: 3.1e-27, bitscore: 93.5,
                     seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEIQFICVDCQELFMEETDKNCCTCGGLLIIKTSKSIFKDNWIV
                     GENQTMWKYYLVVSVQANKRAWEKVSLGEGNTVLDKLDSDNQHIYLKLENTLPSRSYID
                     RCSALLVTKLLEKKIQNILITEATCMSLSVAKYAKHAQIACELALPENTACQLVDAHRN
                     EGVRVSDFVSDQESAANNFILPDFHPYMIEGAKTYAYEIWEQLGHRHPDIVTFSVETSM
                     LAVGTYYGFKDLLEHHLIGKLPRFIIVDIQSTSLPVKSKAVSIPQPLYKELIKMIKETD
                     GHLQTITKTEIIQASKALFMRGYQIDEQSAAAYAGCMRYYRDFSIKNESIVIPLSNFSE
                     IGKSK"
     gene            13038..13532
                     /locus_tag="F7984_RS09760"
                     /old_locus_tag="F7984_09760"
     CDS             13038..13532
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7984_RS09760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7984_09760"
                     /product="hypothetical protein"
                     /protein_id="WP_066103647.1"
                     /transl_table=11
                     /translation="MIDVFHGTSTTNYEKILDKGLTLRTSFSHGKKHGDAIYATTRKHW
                     AKKFGPNIIEFRVNTEHFLFIEDEDYAKLYDSFTNEFVQPYETISAYIYHKQFDKIRNL
                     SGVNNRTNIKLFIRDTEFKIGSLLREMLTSNGYKGIVISSEDSKGPFYDLTIYDLSCIS
                     M"
     gene            13738..13974
                     /locus_tag="F7984_RS09765"
                     /old_locus_tag="F7984_09765"
     CDS             13738..13974
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7984_RS09765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7984_09765"
                     /product="hypothetical protein"
                     /protein_id="WP_066103644.1"
                     /transl_table=11
                     /translation="MAKQHSLTEYLIPGSLLTGLGIGLSIGSPGVGCLVGLGGGFLLTS
                     ICNIFLDGQSKLLGIEELEQRISKLEENAKKNG"
     gene            complement(14101..14979)
                     /locus_tag="F7984_RS09770"
                     /old_locus_tag="F7984_09770"
                     /pseudo=""
     CDS             complement(14101..14979)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016747 - acyltransferase activity,
                     transferring groups other than amino-acyl groups [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006836331.1"
                     /locus_tag="F7984_RS09770"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09770"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKTFDEEAKRWLIDQEIVDCNIQPPGYTSVEMT"
     gene            15254..15628
                     /locus_tag="F7984_RS09775"
                     /old_locus_tag="F7984_09775"
     CDS             15254..15628
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7984_RS09775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7984_09775"
                     /product="hypothetical protein"
                     /protein_id="WP_139891888.1"
                     /transl_table=11
                     /translation="MQKILYRIIWVLILLGINLCALPISIYSIFAVEKGTNITTMDYTL
                     AITIMVISNFITLQLFIAIKKNQKQNAIYGIIIAVTQIIAFILFMHLYEIAGIIIFLLS
                     LIASVTMIIKTWRNKNPALM"
     gene            complement(15644..17320)
                     /locus_tag="F7984_RS09780"
                     /old_locus_tag="F7984_09780"
     CDS             complement(15644..17320)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019240689.1"
                     /locus_tag="F7984_RS09780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09780"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_225983568.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 7.9e-47, bitscore:
                     157.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSILTKGILDLIIIGGGPAGLSAGIYAGRGKLNTLIIEKGNMGGQ
                     AATTNEIVNYPGVRKTTGPLLIEEMKKQCEDFGVKFTKTDVTDVDLSGEVKIIKTINGE
                     YQARSVIIAAGAGPRKLGFPGEAEFTGRGVAYCSTCDGEFFEGLEVFVIGAGFAAAEEA
                     MYLTRFASKVTIIAREPEFTCAPSIADKVFANEHIEVKFNTELLEVSGVEMVQHARFIN
                     NVTKEEWEYTAKEEDGAFGVFVFVGYQPKTEIFKGHVEMDERGYIITDEEMRTNIKGVY
                     AVGDLRPKSLRQVITAVADGAIAGTDVQKYVAEEKERLGIVDEPKEEKPAEKKESAPKE
                     TAKSGKSSLLSDAIKGQLKGIFAKMENDVTLVSIVDESMPKSVELRDFLIDVAELGDKL
                     HLEVYPKGENTEMETKINADKFPVVSLLDHKGNYSGVKFHGVPGGHELNSFILAIYNLA
                     GPGQALDSSIKQSIQAIDKKANIKIMVSLSCHYCPDVVVGAQRIAIENPNVEAEMIDIS
                     NFQDIKKKYKVMSVPAMIINDEQVVFGAKKINEIVAVLQQA"
     gene            complement(17486..18049)
                     /gene="ahpC"
                     /locus_tag="F7984_RS09785"
                     /old_locus_tag="F7984_09785"
     CDS             complement(17486..18049)
                     /EC_number="1.11.1.26"
                     /GO_function="GO:0102039 - NADH-dependent peroxiredoxin
                     activity [Evidence IEA]"
                     /GO_process="GO:0006979 - response to oxidative stress
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="ahpC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1196: alkyl hydroperoxide reductase/ Thiol specific"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /locus_tag="F7984_RS09785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09785"
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="WP_066103636.1"
                     /transl_table=11
                     /translation="MSLINKKLEDFTVQAYHDGEFKEVSLSDVQGKWSIFFFYPADFTF
                     VCPTELADLQDNYDALKEINCEVYSVSTDSHFVHKAWADATDTIGKIKYPMLADPAHVL
                     SRQFEVLIEEAGQALRGTFIVNPEGEIKAYEIHDLGIGRNAEEVVRKVQAAQFVAEHGD
                     KVCPAKWTPGEETLEPSLDLVGKI"
     misc_feature    complement(18102..18115)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     medium, score: 24.88"
                     /tool="antismash"
     misc_feature    18103..18116
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 24.04"
                     /tool="antismash"
     misc_feature    18139..18154
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.17"
                     /tool="antismash"
     misc_feature    complement(18141..18154)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 23.46"
                     /tool="antismash"
     misc_feature    18142..18155
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     strong, score: 26.48"
                     /tool="antismash"
     misc_feature    complement(18142..18157)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    18236..18250
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     gene            complement(18548..19024)
                     /locus_tag="F7984_RS09790"
                     /old_locus_tag="F7984_09790"
     CDS             complement(18548..19024)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013057074.1"
                     /locus_tag="F7984_RS09790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09790"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_066103634.1"
                     /transl_table=11
                     /translation="MTQTNSMYYIEIPESLTPAQQNMMMELEKDAFPGLGAVDEQTLVP
                     LARYGKLILYRQQGDERPVAVCECMRDYNQPDKAYIFGYYVRSDQHGKGLGTQFLHEVL
                     SILRDDGFHKVSLTVSEANTAAVKLYKNIGFTVNELRYGEFGDGEDRLYMEKIL"
     gene            complement(19021..20523)
                     /locus_tag="F7984_RS09795"
                     /old_locus_tag="F7984_09795"
     CDS             complement(19021..20523)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016764131.1"
                     /locus_tag="F7984_RS09795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7984_09795"
                     /product="M81 family metallopeptidase"
                     /protein_id="WP_225983725.1"
                     /transl_table=11
                     /translation="MRIGIAFFYHESHSFSRTKTTIQDFKNEGYFKGNQIFDVYTNTRT
                     EVGGFIDVLRKLEEVEIVPLLCAAAVPSGPVTYETYEEIETELMGLMEAAGKLDGLLIA
                     LHGAMVIEGINDAEEYLLLKIRAKLGVDIPIATTLDLHANISPAIVGITPYHFGFKTYP
                     HIDMYEQGVNAANALMNHLSLGVDYVARCVKIPMLLPSINMKTMEGPMAKMMKLAHRYE
                     EEDGILNISVFGGFPYSDVPSAGASVIVIAKNQLLAERTASDLAKIFWKLREEFIVKLP
                     DVKEAFQLALAMKKNKPIALADISDNPLSGGSGDTTKLLRECIEYNREKTLFGALTDSK
                     AIDICRSVGVGGTVQLSLGGKIYPEFGLPVNVQATVIRLTDGVFYNSGPFNKDLKVDVK
                     GACWIRVGNIDILLIGRPMSANDPELFRHIGIEPSAYRYLILKAKNHFRAAFDPLISEV
                     IYVDAPGAAANNIAQLPYKNIPEQTWPLKNIEFLKVEERKKS"
     misc_feature    21030..21050
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 23.79"
                     /tool="antismash"
ORIGIN
        1 ggttttcttt gtttgtgatg atacgtggta atccaaagat atcaaatggc ggatcatctg
       61 ggtggattgc catttttacg ccagcttctt ctgcaactgg aataatttct ttaatgaaat
      121 actcaaggtt ttcccaaagt ttttcatgat caacattttt gtagtgatca aataattgtt
      181 gcaggtcttc ttttttatag ctggaatccc aacctggtaa agaaagttca cctgttagtg
      241 gatccatttt cttagctact tcttcttcga agataagagc tgtagaacca tctggaagac
      301 ggtattctaa atctgtacgt gtccagtcaa agattggcat gaagttgtag cacacaactg
      361 ggataccagc tttaccaagg ttacgtaaag tcgttttgta gttctcgata tatttgtcac
      421 gagttggcaa accaattttg atatcttcat gaaccggtac gctctcgata acagagatgt
      481 gcataccagc atcttctaca gtctttttca attcttcgat tttatccatc ggccaagctt
      541 caccaaccgg gatatcataa atagctgtta caattccttt catacctgga atttgacgga
      601 tgtattccaa aggaatacta tcagtttttc cataccaacg gaatgacatt tccatagtaa
      661 gtttcctcct aaaaattatt gaagatctat attaaaatag ttcttagcgt tattaaagca
      721 gatgttttca attaagtttt gcagcaatgc cggatcattt ggaatttcgc cagattctac
      781 ccaagtacct attaagttac atagaatgcg gcggaagtat tcatgtctgc tataagagat
      841 aaagctacgt gaatctgtca gcatccctac aaagtgactt aataatcctt gatcagctaa
      901 agctgtcatt tggcgaatca tgcctggttt agtgtcattg aaccaccaac cagaaccaaa
      961 ttggatttta cccgcgattc cttcttcgtt tgtttggaag ttttgaatcg ttgtaccaat
     1021 cagttcgtta taaacaggat tcaaattata cacaattgtt ctaggcaggg aatccctgat
     1081 ttctaacgcg tctagcagcg catttaatgg tgcggctact tcgccttgat cactgatgga
     1141 gtcaaagcct gcatcaggtc ctaatctttt gaacattttt gtgttgttat tgcggattgc
     1201 accaaagtga agctgcattg cccagcctct ttctgtgtag gcctttgcaa gagcaatcat
     1261 gatggctgtc ttgaatttat tttcatcctc taggcttaca gctttaccgc tacggccaga
     1321 ttgataaatt ccatctaatt cgctttcatc gaattcagca aatggaacct ctgataggcc
     1381 atggtcagaa attctgcagc ctttttcgtg gaaatattga actcgatcca atagagccgc
     1441 aatataatcc gcataagttg ctaatgattt gtcagcaacc ttttcaagag tctccacgaa
     1501 tggaacgaat gtagctttat tgatttccaa tcctttgtca ggtcggaatg aaggaagaac
     1561 cttcactggg aaatcaggca attcagcgat ttgcgcatga tacataagat catccgtcgg
     1621 atcatctgtc gtgccaatta cttttacatt tgagcgtttg atgagttcgc gaacagaaaa
     1681 atcatcttgc tgcaacaatt cattacaacg gttccaaatg ctttcccatg tttgttcgtt
     1741 taataattct tcaataccga agtagttttt taactcaata tgagtccagt gatacaaagc
     1801 gtttccaact gtatatggaa cagttttagc ccaagcctca aacttctcct tcggatcggc
     1861 atcaccagta acatactttt caggaatccc atgtgctctc attgctctcc atttataatg
     1921 gtcaccttcg agccatagtt cagttatatt tttaaattta cgattctctg caatatcctt
     1981 tggggataaa tggcagtggt aatcataaat aggcatattc ttagcgtatt catgatacaa
     2041 cttcacagct gtttcatttt gcaatataaa gttttcatgt ataaatgaac tcatccgctt
     2101 taccctcctt tatgtagcag gtcttgatta tttattttga agtgttgcta aatggtccat
     2161 aaactctctt gcaactgctt ggacagagct gtaatctcca tctttcacat tcttcgttaa
     2221 ggcacttccg atacctactg caaatgcacc aacttcgatc cagtcagcca agttatcctt
     2281 gctaacaccg cctgaaggca tcatttgaac atgtggaagt ggtccgtgta catccttaat
     2341 gaaggatttg ccaagaaggc ttccaggaaa cattttgata acatcagaac cgtatgtaac
     2401 agcctccatt acttcagtta cggatccgca acctggtaag taaggaacac aataacgatt
     2461 acacattaat gaaatgtttt tatcaaagtg tggactcacg atatagcgtg cacccttcat
     2521 aatagcaaga cgagctgtag cttcatctaa tactgttcca gcaccaatga tcatgttgtc
     2581 atcattcatg cttgcaagtt cagcaataac gtcacctgca tcaggtgttg taaatgtaat
     2641 ttctaaagaa cgaataccgc ctgcatatgc ttgtttagca atttcaacag cttcttcttt
     2701 tgtcttaccg cgaacaactg ctacaacata gcctttgcgc atttcattta atacttcaaa
     2761 ttttggtaac ataacattca cactccagtt ttcgagtcga tatcaacaaa acaaatagcg
     2821 atagattaat cgctatttgt tttcaatttt ttagccctaa ttaaacacca gaatatgcag
     2881 agaacgcacc atcaactggg atgattacgc cattaacaaa gctggatgct tcatggcttg
     2941 caaggtataa cattgttcca acaagctctt ccgcttcacc aaaacgatcc atcggcgtat
     3001 tgcgaaggat tttctcagaa cgctcagtgt aagagccatc ttcgtttttc aacaattttt
     3061 cattttgtgc tgtaacgaag aatcctggag caattgcatt aacacggatt ccaactttag
     3121 acatgtgaac cgctaaccat tgtgtaaagt tacttactgc agctttcgca ccgctgtaag
     3181 caggaatttt tgttaatggt gtgtatgcat tcatagaaga tacattgatg attgttgcac
     3241 ctttacgatt taccatatca cttgcaaatt cttgagaagg taataaagta cctaagaaat
     3301 tcaagttgaa tacgaattga actccttctg gatctaaatc gaagaaagtg attgtatctt
     3361 tcaattgacc attcaaatct tctgggaata aatattcttt agtagtagtt ccaagtggat
     3421 ggttaccacc agcaccgttg attaagatat cgcaaagtcc taatttttct tttacaactg
     3481 cgtgtgcagc ttttaggctt tctttgtcta atacgtttgc ttcaacacca atcgcaattc
     3541 cgcctttttg gcgaacttct tcagctttct tttcagcatt ttctaaagcg cggtcaagaa
     3601 tggcaacttt cgctccacat gcagccaaag catcaacaaa tgctccgcaa aggattccag
     3661 cgccgcctgt aacaaccgca actttatctg ttaaatcaac tttaaaaggt aaagtagtca
     3721 tttcgtcata cctccatata tttgcattga aattttcata aacactatgt atacgtgtta
     3781 ttgcatgctt gtatactagc atacttgacg agttatatca ataatttatt tttctaaatt
     3841 tgaacataac tcatacatta aatgcccatt acttatcatg ctctaccaga ttcaaagtat
     3901 gtacgtaatt cattaaatac tcttcctttt acatcctttt cttcttttta caaattcccc
     3961 aataacaaaa aaagatagcc catttaagag ctatctcttt actaattatt ttttacgtct
     4021 ttcagcaata tcaattgcaa gttgctctgt acgtttcttg tttaatgggt acaagaacat
     4081 taggattaag aaaataactg catagaacaa cgctggtgct aatgtaccaa gtgcatgaat
     4141 tccatttaac gtaccttctg tttgtgtttc aagtgctgca ttgtaaccaa ctgcagcgat
     4201 caagaaaccg ccaagaccac cagcaacggc ttgacctact ttacgagcga aggagtaaac
     4261 tgaataaatc gttgcatctt cacgtaaacc agttaagaac tcatgataat caataacatc
     4321 cgttacaaac gcccaaataa caacgtttaa gaatgctgta ccaaacatac caagtgctgc
     4381 aatccataca aatgtcattg catcaatatc tttcagcatg aatagtacga agtaaatgat
     4441 agccgcaaat cccataccaa tagaagcaat ttctttttta ccgaaacgag caactaatgg
     4501 tttaaccaac ggcattgcta taaatgctgt aactgtagtc ataacaccaa caagacttaa
     4561 cgctgcagtg ctagtgaaat aatctttaaa taggtatacg tttactgctc ccataagcat
     4621 gctgtttgtc atgaataata aagatgcagt taaaatccaa ataagtggtt tgttttgacc
     4681 gatcgcttta agcgttttac gaagatccat tttttctgca tcatttgttt caggaacgat
     4741 acgttcagtt gttaatttgt agcaaccgat gtaacaagaa attgccaaca caccaaagat
     4801 acaagcagcc ataaacatac gatttgcatc gattttgtta tcaacaaaga caatcattgg
     4861 tccgactgca ttgatgatca agctcgcaag catcatacca gctgttctgt aagtagataa
     4921 agaagtacgt tcaactggat tatctgtcat aacagaagcc atagatccgt aaggaatatt
     4981 aactgtactg tacaaagtac cccaaacgat atatgttacg aacgcccatg ccaagtagaa
     5041 accatcaccc ataccaggaa tcgtaacgaa cattaaaacc cctgagaaaa ctaatgggaa
     5101 tgacattctt agtacccatg gtctaaattt accattttta gttggttttc tagtgtcaat
     5161 aaaacgtccc caagttacgt ctgctactgc gtcccataaa cgagcagcca tgaagagcgc
     5221 accaactgtc gctgcattga tgccaaaaat atcggtatag aataccatta agtaagcact
     5281 taccaataag aaaaagaaat cgtttccaaa gtcacctaat agatatccaa ttttgtccct
     5341 catgccgaaa ggacgaacat taggagtagg gttttctttt ggtgagcctt gttttttcaa
     5401 agcttctgca ctcatttaat tacctccaaa tactataata gttataaatg acgaaaatac
     5461 cgccaagcag gttcaaacac ttacactcca tacttccatc aatcttttgt aaacagtaaa
     5521 ggcttcttaa ctggtagtat atacttactc ctaaatttta tttacatttc attttgctca
     5581 ttatttcaca aagaaaagta aaataaaatg caggaggtaa aattgttcta aaactgatca
     5641 ttaatatttc gtgtaaaaat aaattataat tactattgct cattatttca caaacaagag
     5701 taaaataaat gtttgaaact tcttcttggt tcaaactatg tttcgttcat ttacactagt
     5761 atactagcat gcgcatgata agattaaaag accttttttt aattttttag gaggtaaaat
     5821 aaaccaaaca agaatcctca ctaatttttc tgtttccgtt ttcataatca aaactttaaa
     5881 cggtacaaag ctgaacagat aatgacttac gtttttctag cttataaagg gtcttattac
     5941 ttctctcctc atatgcatat aatcatcctc ttatcaccgc ttaatctaat gagaaatcaa
     6001 tatagaatgt ttttggaaaa gcgagcaaca aagcctctga tttgtcctaa tctaacagga
     6061 ttcaaaaagc tattaaggag tactagctga agtaccagtg taatttccat aaagtgcaaa
     6121 ttatttgact tgtcagacgg gaagcgtaat atcaaattat catttaaatt tggaggtgaa
     6181 ggttactttc actctatagt agccaatagg ttcatgaaat atttagtcat atgctcgcaa
     6241 atccttgttc ttttcctttt ttattatatc ggtgtattca tacaagagct gcttagcatt
     6301 ccagtccccg caagtattat cgggttatta ttactgttag tttgcttaaa attcaaagta
     6361 attccagttg aatatattaa ccgtggagct ggttttttaa ttgctttctt gcctttgtta
     6421 tttgttccaa tctgtatcgg tgttataaag tatcccgagc tattctcctc taaaggtttc
     6481 attattatgt ttgtcgtatt tattagtaca atctttaccc tgctgatatc cggaggaacc
     6541 agtcagattc tcgaaaattc agtgaacaaa cgaaaggatc aaaataaatg gggaaattac
     6601 tgattgccat ttcgattatt attataactg tcatcatatt tcttttattg aataaactgt
     6661 atatccgatt ttccaatcca tttcttttgc caatcttaac aacaaccatt ttaattgttt
     6721 gcatcctttc agtttttaat atttcttatg atacatacat gattggcgga gagtggatta
     6781 atcaattact tggtcctgca gtagttgcac ttgcttttcc gctttataaa caatggagaa
     6841 tgttgaaaga tcatatattc gtcattttag gaggtgtctt tcttggcgta ttggcaggaa
     6901 tggttagcgg acttctattt agtaagctgg ctggtgtagc cgaagagact gccgtttcca
     6961 tattgccaaa atcattaact acaccagttg ctgtacagat ctccgaggaa ttaggcgggg
     7021 ttccagcatt aacagctatt tttgtcatga tagcaggtct aaccggagct attttagggc
     7081 cgcttatttt aaatctattc cacataacaa atcccgttag taaagggatt gctttgggca
     7141 gcgcatccca tgcaattggt acctcaaagg catttgaatt cggtgaatta accttttcca
     7201 tgagttctat ctccatgaca ttaagcgctg tttttggttc cattgtagga ccaattatca
     7261 tgaacctctt aattaactag gggtaaaaaa agtccgtttt tgctgaaacg gacttttcat
     7321 atactttgcg ctacctcttt aatcccgtaa ttttcgttct caatttgttt caccttatcg
     7381 ctgcattcct gtaattgttg attcagtttg ataagctcct tttcatattt acttttaatc
     7441 ttattctccg tttcaatcat gaaatcaata tccgttaatt ccttctgtat ttgtttaatc
     7501 ccaattcgat cagcccgttt aaagtcacta tccgaatcta aaatatctcg gactaagctc
     7561 tcaagaagct catccacttt tttctcttta ccaagctgat caagtgtcac tgacatattc
     7621 agcaatttat tagtaaattg tttgattaaa ctggtttcca atatttcatt gcttttggat
     7681 gcagctaatt ggtttaattt tttttggatg tgaatgtact cagtacgatg tttttcaaaa
     7741 ctttgattta tcgtcaactc atttatatcc ataaaaagga gtgttgattt aagcttgtac
     7801 atttcgatat tcaatcgttc ctgaatatgt tttttttgat ttgcaaattc gtttatccgc
     7861 tgccgggatt tatggacaga tgaactcatt tcgatatgtt tcatttctaa taaatcagaa
     7921 tgatactcca attgacggta ttcctctacc cttcttttcc attcattcag gaataaaact
     7981 ggactggata cagaattttc atcgcataaa tacgctaaag ttatctgcat taggataaaa
     8041 ggcattagcc ttttttttat ggcatgatgc tgatagttta tttgaaggac tctgcctcca
     8101 aggacatagg gtgtaataaa atatggagaa gttaataatt ttgtcgtagg ggaaatattt
     8161 tcttgattga ttaatgggat attcattgga agcttttcat tgtagttcat taaaagcttt
     8221 gtaaacatat caaaaaatga aggaagactg atatttgata cctgaataag taaagtggat
     8281 aattctattt ctttaaaaac ctcaattgac aaataatttg caggcaattg ttgaagaagg
     8341 atccattttt catcctctga gagctgaatt ataaattcat atatagtgtt taaaaaatcc
     8401 tgctgatcct caactgaaag attttgaaag cgatattcca cctcataaaa tagctgtctg
     8461 agctgatagt gaataatgtg atggatcctt gtaaactcaa tttgttccgt gttttgaagg
     8521 aatgattttt cctgatttat atatatttga tatacttttt caacaatttc ttcacattga
     8581 ttatccacat ggaaagcttc actataataa acaccttcta gttcaagtgt tttattcatt
     8641 tcctgaaaca aactgacctg caatgcctca tctgagagat gaatatattc atcggttttt
     8701 tcaagaaggc agtttacata atcagtgtta tgtttcctag aaatgatttt gttaaaatta
     8761 aatgggatta gttcttttag atttaaattc gttaataaac tataaatgat tcgtaaatcg
     8821 gctcctttca acgaatagat actgttagat aataaagttc catccatata actcactctc
     8881 ccgaccttaa cagatagaaa cattttaaca tggaaatagt tgttaatata cgtgtgagtg
     8941 taaatctttt tcaatttaat taagattgat aaaagtgtaa ttcataaaaa gcgggacaaa
     9001 gaatggttta actacaccat gaataatcac tgcataaaaa acagcatcca tatccctaaa
     9061 aggtaaaatg gatgctgcat tattttcgtt tctagtaaac ttcatcattc attttctttg
     9121 attgttcagc acaaacctcc atcgctttaa tgacagaact tctgaatcct tgtgcctcca
     9181 gttctgtgat ggcagcaatc gttgcaccac ctggggagca aacttgatcc ttcagttctg
     9241 ctggatgaat ccctgtttcc aaagcgagtt ttgccgatcc cataatggtt tgttcagcca
     9301 ttcgataggc cttttttcga tctatcccta atttcacagc tgcatctgcc attgcttcaa
     9361 ttaatacgaa aatataggct ggagaagaac cgcataaagc aataaacgct tcgaaatcat
     9421 cttctttaag aatttcatat tctccaaaca cactaaataa ctggcagatt tcctctaact
     9481 cttctcctgt gacatggtca tttggacaaa tagctgtcat ccctgcattc accaggacag
     9541 gagtattagg catagacaat ataaattttg attctgctcc aatccattca tccatttgct
     9601 ttattttaac tccggcagca atcgaaataa gaatcttctt atcagtaaca tattctctta
     9661 tttctttaat aacttcttca tattggtttg gattaactgc taaaaagatt atatctgaat
     9721 ttaggacaac ttctttatta tccagagttg tatgaatcgg ccacttttcc gaaatagcaa
     9781 cttttgattc ttctgagcgc acagatacca acaattgatc agcgagtttt tgattactgt
     9841 taatcaaaga accaaccatc gcttttccca tatttccaca gccaataaaa cctattctct
     9901 tattcatgct tcaacaccta ttcttcctca tttgccacta ttctaacata aaacaagtaa
     9961 aaaatagaaa attaggatta gcgcgctcat tcccatgtag ctatgtatgg tcagtaatca
    10021 gtttcttttc ataatgaccc agtgctaaca gaggaaaaat ataattatag ctttcataaa
    10081 tgatataaaa accaccccgt aaaccgagac ctgttggata cctgtttgca ttaggatggt
    10141 ataactcttc atttattaaa aagttaaccc ctttctgaat ggttggtgaa gttgcccgct
    10201 taactgctaa gagagcatcc aatgcccagg ctgtctggga tggagtactg taggacaatg
    10261 ggatataacg ttctttatct gcactcatac aggattctcc ccatcctcca tctttcagct
    10321 ggatagactc cagccatctg attgcttttt ggatagaagg gtgctcaggc ttgattccga
    10381 ttgcacatag tccagtcacc gctgcccacg ttccataaat ataacaaaca ccccattttc
    10441 cataccagct accatctgat aattgttctt tcagaagcca ggcagctgct cttttaataa
    10501 aggaatggtc atgtgttaat ccagcataat tacccataaa ttctaaaaca cgacctgtca
    10561 ggtctgaggt agaatcgtca atgatggcat cctttgcatt ttcaattggt agataagcaa
    10621 ataaagaatt ataggcatct ttttcaaagg ctccccatcc tccatcctta ttttgcatgc
    10681 ccttcaaata cgagaaacct tttttccaag caagatttgc ttgttggttc aatttacttt
    10741 gctttgttaa tgctcgtaaa accgcacttg tatcatcatt atccggtata taatgattgc
    10801 tgtcagaaaa tccccatccc ccaggaatca catctggagc atgtactgtc caatcccctc
    10861 tcgtgctttg ttgttttttc agcaaatacg catttgctcg atcgataaca ggatgggttg
    10921 ccttaacccc cgcttcttgt aaggaatagc ttaataaagc tgtatcccac accagggagg
    10981 gtgaattttg caaatgaagg ccataaggtg tatccgttaa atagctcttc attccctcca
    11041 tcgccttaag aataatcggt gagtttcgtt tataccctaa ggcaagtaaa gcataaatca
    11101 tataacaggt agccgaacta taactataca gtgtcccatt tttctcaacc cggtcaatca
    11161 ttagcttttc tgcagattga tagcctgctt tttgccaaga ggatggagaa aaattgagga
    11221 tctttagttg attaatcaat tgttctgtct gaaaaaaacg ttcctctcta aaccatccac
    11281 cttcttgtcc atcaaggaaa ctcttatcta tccccttgtg ttcatacata aatcgtttat
    11341 taatgcagat ggtcatagga gttaaatgca ctctggcata gttactgcat tgatacatgt
    11401 taaaaggtac atggggcggg agcataaaat aactcatcgg aaatttaaaa aagcttggat
    11461 aattatacat tccattgact gcgagcatca ttttagtcat aaagtgagat tttgatactc
    11521 caccatgctt aattataaat tgttcagctc gcttcatctc ctcatccatc cgagtaaatt
    11581 tgcctgacac aagcagggct gtataagatt gaacggtggc agataaatta ccatccttct
    11641 catccggata gatactccaa gacccattat cattttgagt gcgcagcagc cgtttcacta
    11701 gttgatgcat taattcttct tcatctattc ctaaggtccg tataagtaag atcataaaac
    11761 aatccgttaa tgaagatcct tcaaagttga atgtccatga acctgattga ttttgtgttt
    11821 tttccagcct ttctagcttg gaggctatat acttctcaac gttagatttt gtcataacta
    11881 tcttatcacc ccaaaaaact atttggattt tcctatctcg ctaaaattac taaggggtat
    11941 cacaatcgat tcatttttga ttgaaaagtc tcgataatat ctcatgcatc ctgcgtaggc
    12001 tgctgcactt tgttcatcta tctgataacc tctcataaaa agcgctttac tggcttgaat
    12061 gatttcagtt ttcgtaatgg tctgtaagtg tccatctgtc tctttaatca tttttatcaa
    12121 ttctttatat aggggttgag ggatagatac cgctttactt tttacaggca gagaagttga
    12181 ttgaatgtcg acaatgataa atctggggag ttttcctatt aaatgatgtt ctaaaagatc
    12241 cttaaatcca taataagtac ctactgctaa catactggtt tcaaccgaga acgtaacgat
    12301 atcaggatga cggtgtccca actgctccca tatctcatat gcatatgttt ttgctccctc
    12361 aatcatatag gggtgaaagt cgggtaaaat aaaattattt gcagcagatt cttgatcaga
    12421 aacaaaatcg cttactctga ctccttcatt tctgtgtgca tccaccagct gacaggctgt
    12481 attttcaggt aaagctaact cacaggcaat ttgagcatgt tttgcatatt tagcaacaga
    12541 aagactcata caagtggctt ccgttataag gatgttttgt atctttttct ctagtaactt
    12601 agtcactaat aatgctgagc atctatctat ataagatcgg cttggtaaag tgttttctaa
    12661 ttttaagtag atgtgctgat tgtccgagtc caatttatcg agcacggtat tcccctcacc
    12721 tagtgatacc ttctcccatg cacgtttgtt tgcttgtact gatactacta gatagtactt
    12781 ccacatcgtc tggttctcac caacaatcca attatcctta aaaatgcttt tacttgtttt
    12841 gattattaac agaccgccgc atgtacaaca atttttatcc gtttcctcca tgaatagctc
    12901 ctggcaatct acacaaataa attgaatttc actcattcct gctcctctcg ttaatcagtt
    12961 aatcaacata ttaagatgga aaagtttacg tttttcattt atgatgatgg tattaataaa
    13021 aatatggagg cgattagatg attgatgtat ttcatggaac ctctactacc aattatgaaa
    13081 aaattctcga taaaggcctt acactacgga cctctttcag tcatggaaaa aagcatggtg
    13141 atgctattta tgccacgaca cgtaaacatt gggctaaaaa gtttggacca aacatcatag
    13201 agtttcgcgt caatacggaa cacttcttat ttattgaaga tgaggactat gctaaattat
    13261 atgattcatt taccaatgaa ttcgtacaac cttacgaaac gataagtgca tatatatacc
    13321 ataaacaatt cgataaaatt cgtaatttat ctggagttaa taacagaaca aacattaaat
    13381 tatttattag agataccgaa tttaaaatag gcagcttgct tcgcgaaatg ctcacctcta
    13441 acggctacaa aggtattgtt atctcatcag aagacagtaa aggtccattt tatgatctga
    13501 caatttatga ccttagctgt attagcatgt aaaccacctc ctttttactt attcgagaaa
    13561 cctcaccact atcctcatgg cgttttttta aaactgtttc ctgctgaata ataagtttat
    13621 agatactaaa tggttaaata aggttaattt caagaatatg tatatattct gcaaattaaa
    13681 gttgttataa tattaaccag aatacataaa ctttcgaaaa agattggagg agatttgttg
    13741 gctaaacagc attcactaac tgaatacctt attccaggca gtctgttaac tggccttgga
    13801 attggactat ccattgggtc tccaggtgta gggtgtcttg ttggtttggg cggtggcttc
    13861 ctattaacgt caatatgcaa tatttttttg gatggacaat ccaaactatt agggatagaa
    13921 gaactcgaac aaagaatcag taaacttgaa gagaacgcaa aaaagaacgg atgaatggtg
    13981 aatagtcgca ccatcttcgt tcttttttct ttgtgattat ttaagtttta accttacttg
    14041 atttaaataa tttcccctta tatgatcatg tgattcttgt tcaaacaatt gatcatatac
    14101 ctattcgaaa ctttcctttt tcaactctcg gttatacact tcgaacaatt tttccactga
    14161 aataccattg attttcattc ctgttatctt actttccgtg atttccagat tacttaggtc
    14221 acaattccta atctttgatt cctggaggtc acatctttca aaggatatcg gatttttgtc
    14281 atctccaaga tttgtgtcca taaattcgat tcctgcaagg gtaactaatc tcattttaga
    14341 aaaggatagg tttaaatctg caaaatagga gtgttttaaa tttatgtttt ggaattttga
    14401 ctgactaaga ttacagttac tgaaatgagt acttctcaag ttactgttac taaaagaact
    14461 ctcttctaag ttgacttggt accattctgt atatgccata tcacaatttt catatggttt
    14521 atttgaaata tcatgatttt ctaccaaatt atcagatttt gtcaaactct ctttcctctt
    14581 tatgtagcaa aactcatctt ccgacttaaa gatcgtttta tagcccaatt tctcgtaaaa
    14641 atggtgatta ttaagctgtc tgctggatgt ctcaaggtcc cattgtctta cgcttggaaa
    14701 tttctcctct attaattcca ttactctgga accgattttg agattctgaa aatctggatc
    14761 aacgtatata cggtctattc ttccatatga cttaccggta atcgtcacga taactccacc
    14821 aactatagcc tctttataga tgattttgta ataggataat tcttcgatca tatattaagt
    14881 catttcaact gaagtatagc caggaggctg gatattgcaa tccacaatct cttgatctat
    14941 aagccatctt tttgcttctt catcaaatgt tttcttcatt agttctgtta atttttcagc
    15001 gtcacaaaag attgcttttt caattgttaa caagttgtaa tctccttttt caaaattcgt
    15061 atggataaac tgatgaatag ttctaaattt tgtaactatc aagtgaattc taccataatt
    15121 tacaagttgc acgtcattta tttagttatt tgtttaagaa tacaaacaat ataaactgaa
    15181 gtatttatag tcgggtataa ccatctctat attgcacaaa atgtaaaata gaatataaca
    15241 aggagtctaa tatatgcaaa aaattttgta tcgtataata tgggtattga ttttattagg
    15301 cataaatctt tgtgcccttc ccatttcgat ttattcgatc ttcgcagttg aaaaagggac
    15361 aaacattacc acaatggact atactttggc aattaccatt atggttatca gtaatttcat
    15421 tacactccag ctcttcattg ccataaaaaa gaatcaaaaa cagaacgcaa tttatggaat
    15481 aatcattgct gtcactcaaa taattgcctt cattttattc atgcatttgt atgagattgc
    15541 aggcataatc atctttttac tttcactcat tgcatctgtt accatgatca taaaaacctg
    15601 gagaaacaaa aacccagcct tgatgtaagg ctgggttaat tgtttaagct tgttgtaaca
    15661 ctgctacaat ttcattaatt tttttagctc caaagactac ttgttcatca ttaataatca
    15721 tggctggaac actcattact ttatatttct ttttaatatc ttggaagttg ctgatatcaa
    15781 tcatttctgc ttcgacattt gggttttcaa ttgcaattct ttgagcaccg acaacaacat
    15841 cagggcagta gtggcatgat aaagatacca taatcttaat atttgctttt ttatcgattg
    15901 cctgaataga ctgcttgatt gaggaatcta acgcttgtcc aggacctgcc aggttataaa
    15961 tggccaagat aaaggaatta agctcatgtc ctcccggtac accatggaac ttcacgccac
    16021 tgtaattccc tttatgatca agcaacgaaa caaccgggaa tttatcagca ttgattttcg
    16081 tttccatttc agtattttcg ccttttggat aaacttccag atgaagttta tcgccaagtt
    16141 cagcaacatc gatcaagaaa tcacgtaatt ctacagattt aggcatactt tcatccacaa
    16201 tacttactaa tgttacatca ttctccattt tggcaaaaat accttttagt tgtcctttga
    16261 tggcatcgct tagtaagctg ctcttaccac ttttagctgt ttcttttggt gcagattctt
    16321 ttttctctgc cggtttttct tcttttggct catctacaat gccaagacgc tctttttctt
    16381 cagcaacata tttctgtacg tctgttccgg caatcgcccc atcggcaaca gctgtaataa
    16441 cttgacgtaa agattttgga cgaagatctc caacagcata tacaccttta atatttgttc
    16501 tcatttcttc atctgtaata atgtaaccac gttcatccat ttctacatga cctttaaaga
    16561 tctctgtctt aggctgatat cccacgaaaa caaatacacc gaatgcgcca tcttcttctt
    16621 tcgctgtgta ttcccattct tccttcgtta cattattaat aaatcgggca tgctgaacca
    16681 tctccacccc tgaaacctca agcaattccg tattaaattt aacttctata tgttcgttgg
    16741 caaaaacctt atctgcgata gaaggagcac aagtaaactc aggttcacga gcaataatgg
    16801 taaccttgct ggcaaaacgg gttaaataca tcgcttcttc agctgcggca aatcctgctc
    16861 caatgacaaa cacttctaat ccttcgaaga attcaccatc gcatgttgaa cagtaggcaa
    16921 caccacggcc cgtgaattct gcttctccag ggaatccaag tttacgagga cctgcacctg
    16981 ctgcaatgat tacagatctt gcctgatact cgccattgat cgttttgatt attttaactt
    17041 ctccggatag gtcaacatcc gtaacatctg ttttggtaaa tttaacacca aaatcttcac
    17101 attgtttttt catttcttct attaataaag gtccagtcgt cttacgaaca cccggatagt
    17161 taacaatttc atttgtcgtt gcagcttggc cacccatatt tcctttttca ataataagag
    17221 tgtttaattt tccacgtccg gcataaatac ccgctgacaa tccagcagga cctccgccaa
    17281 tgataattaa atctaaaatt ccttttgtca aaatactcac ctaatttagt aaacttttta
    17341 ataaaaaagg tacttatcat tttaagtacc tcatttgatc atctgataga aaaaacattc
    17401 aaaaactgga caagcagctg tcagtcctta agataaaatt tgcactcatc ttccattaag
    17461 aaagataaat gcaaatgatt aataattata ttttacctac taggtccagg cttggctcaa
    17521 gtgtttcttc accaggagtc cattttgctg gacatacttt atcaccgtgt tctgcaacaa
    17581 actgagcagc ttgtacttta cgcacaactt cttcagcatt acggccaata cctaggtcgt
    17641 gaatttcata tgctttaatt tcaccctcag gattcacaat gaatgttcca cgaagcgctt
    17701 gaccagcttc ttcaattaat acttcaaatt gacgagaaag aacatgcgcc ggatctgcaa
    17761 gcataggata tttaattttg ccgattgtat ctgtagcgtc tgcccatgct ttatgtacaa
    17821 aatgagagtc cgtagatacg gagtacactt cgcagttaat ttctttaagg gcatcataat
    17881 tatcttgcag gtcagctaat tcagttgggc acacaaaagt gaaatcagct ggatagaaga
    17941 aaaagattga ccatttacct tgaacatctg aaagacttac ttctttaaac tctccatcat
    18001 ggtaagcctg tactgtaaaa tcctctaatt ttttattaat aagtgacata tcgtatatcc
    18061 tcctaaacaa tatcatcatc taagtgatgt ttaatactat attataataa ttattaaaaa
    18121 gaaatttgtc aattgcttat ttataattat tatcatattc ctttaaaatt ttccgctctt
    18181 tccattaggt aaactcaata aaaactctct atataaacgg taatcaggat caaacataat
    18241 tactgtcgat acagtaaatt tatcaattga attgtatttt aatgataaaa cgtgagggaa
    18301 atcaccgaat tatattatat aaatataatt tattttgctt ttttctttca cttgctagta
    18361 tgcccaaaaa cgttcatttt tttcatctgt ttatgtttca atacaatcta tttatcaagg
    18421 tactttttat cttcatttga aggttttgtt ttataaaaag aagagccaca ctggctgtaa
    18481 tagtcccttt gcagccaata atcatcaaag aaaaaaacgt gtgattagtc acacgtcctg
    18541 ttgttgatta taaaattttc tccatataca accgatcctc accgtctccg aattcaccat
    18601 accttaattc atttacagta aaaccgatgt ttttatataa tttaacagca gccgtgtttg
    18661 cttcgcttac agttaaactg actttatgaa aaccatcatc cctcagaatg ctcagaacct
    18721 catgtaaaaa ttgtgtcccc aatcctttcc catgctgatc tgaccgtaca tagtagccaa
    18781 atatataagc tttatccggc tgattataat ctctcataca ttcacaaacc gcaactggtc
    18841 gttcatcccc ctgttgtcta taaaggatta gttttccgta tctcgccaaa ggaaccagtg
    18901 tttgttcatc taccgctccc aacccaggaa atgcatcctt ttcgagctcc atcatcatgt
    18961 tctgctgtgc aggcgttagg gattcgggta tttcaatgta atacatcgaa ttcgtttgtg
    19021 tcatgatttt ttcctctctt ctacctttag aaattctata ttttttaagg gccatgtttg
    19081 ttccgggata tttttatagg gtagctgtgc gatgttatta gcggccgcgc ccggtgcatc
    19141 aacataaatg acttcactta tcaacggatc aaaagctgcc ctgaaatgat ttttagcttt
    19201 caatatcaaa tacctgtacg cacttggttc tatcccaata tgacgaaaaa gttcaggatc
    19261 attagcagac ataggtcttc caattaggag aatatctata tttcctactc gaatccaaca
    19321 agcaccctta acatctactt tcaaatcttt attaaatggt ccactattat aaaatacacc
    19381 atcagttaac ctgataacag tcgcttgcac attaaccggt aatccaaact caggatagat
    19441 tttcccgcca agtgacagtt ggacggttcc accaactccc acactcctgc atatatcaat
    19501 tgccttagaa tccgttaatg ctccaaaaag cgttttctct ctattgtatt ctatacattc
    19561 tctcaaaagc ttcgttgtat ctccactgcc accgctcaac ggattatcag aaatatcagc
    19621 taatgcgatt ggtttatttt tcttcattgc taacgcaagc tgaaatgctt ctttaacatc
    19681 aggcaatttg acgataaatt cttcccttag tttccaaaat attttggcca agtcactggc
    19741 agtacgttcg gccaacaact gatttttagc aattactatc acacttgcac ctgcgctcgg
    19801 tacatctgaa tatggaaatc caccaaatac ggaaatgttt aaaataccat cttcctcttc
    19861 ataacggtga gcaagcttca tcatttttgc cattggacct tccattgtct tcatattgat
    19921 tgagggaagc agcatgggaa ttttaacaca tctcgctaca taatctacgc caagcgaaag
    19981 atgattcatt aatgcattcg cggcatttac tccttgctca tacatatcaa tatgcggata
    20041 ggttttaaat ccaaaatgat agggtgtaat tccaacgatg gccggactaa tattggcatg
    20101 tagatccagg gtcgttgcaa tcgggatatc taccccaagt tttgctctaa tctttaaaag
    20161 taaatattct tctgcatcat taattccctc aatgaccatt gctccatgca gggcaatcaa
    20221 taatccatca agctttcctg ccgcttccat taaacccata agctctgttt caatttcttc
    20281 gtatgtttca taggttaccg gacccgaagg aacagctgct gcacaaagaa gggggactat
    20341 ctctacctct tcaagtttcc tcagaacatc aataaacccg ccaacctctg tccttgtatt
    20401 tgtataaacg tcaaaaattt ggttcccttt aaaataaccc tcattcttaa aatcctgaat
    20461 agtcgtctta gttctagaga aactatggga ttcatgataa aaaaaagcta ttccaatcct
    20521 catttgtttc acaagggaat ccctcctata gataagtcat atacactgat ttccattccg
    20581 tcatactatc caaagcatga tgggatactt cacgatggcc attccctgaa tacttcatcc
    20641 cgccaaacgc aacaccaatt tcagcattag cagttccgtt attcacataa accaatccac
    20701 tttcaatttc agcagcagct cggttggcaa tagacaaact gcttgtgaaa atggatgtcg
    20761 acagtccata tttcgtatca ttattaacct caatcgcctc ttcatagctg tccacttcaa
    20821 taaaggcaag aacaggtcca aatatttctt ctttagcaat cgtatgttcc tttttcacat
    20881 cactgaaaat agttggttca aaaaaacacc cttcttcgtt cgctaatttc tttcctccac
    20941 actccaataa ggctccttct tctgttgcta tcctcacgta tttctcaacc accttcattt
    21001 gctgctcatt taccaaagga cctaagtcaa tattttcact aagaccatta cctagtttca
    21061 attccttcgt taactttacg acccttttca ataaatcctc tttaatcgat tgttcaacaa
    21121 taacccggct tgtcgccgta catttttgcc cagttgttcc atatgcacct ttaacaatac
    21181 actctgctgc ataatctaaa ttagcgtcct gtagaacaat tgctgcattt ttcccaccta
    21241 gctcaaggga aacccttttt aattgtttgg cacctacctg tgaaagcagc aagcctactt
    21301 cagtagagcc tgtaaaagag atcactttga catcttcatg ttcagcaagc tgcattccca
    21361 cctgactgcc gctccctgta atgagattta aaaccccatt tgggagacca atttcatgaa
    21421 agacttgcat aaatatacct gctgagagtg caacctcaga agctggtttc cacacaatcg
    21481 tattcccact gattaaagca gcacaaattt tataagcggc aagcgctacc ggaaaattcc
    21541 atggagtgat acatgcaact acaccaagcg gctcacgatt catcgtaatc gttcgattgt
    21601 tgttgccgga agcaatggtt tcaccataca ttctgcgacc ttccccagcc atatagcggc
    21661 atgtttctat gacgacattc acttccccgc gtgtttccgc cagaactttc cccatttctt
    21721 tggtcataac ttcggctaat tgatctcttt ttcgttcaaa taattctgct gccttccata
    21781 aaaatacagc acgttccggc gcgggtgttc gtctccagct tttaaaggca aggtgagcat
    21841 gctgtacagc ctggtctacc tggcttgaag ttgcg
//
