LOCUS       NZ_WBPF01000021        25238 bp    DNA     linear   CON 16-NOV-2023
DEFINITION  Bacillus sp. CH140a_4T NODE_40_length_870917_cov_69.246407, whole
            genome shotgun sequence.
ACCESSION   NZ_WBPF01000021
VERSION     NZ_WBPF01000021.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. CH140a_4T
  ORGANISM  Bacillus sp. CH140a_4T
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 871015)
  AUTHORS   Olmedo-Alvarez,G., Saldana,S. and Barcelo,D.
  TITLE     Bacillus from the desert of Cuatro Cinegas, Coahuila
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 871015)
  AUTHORS   Olmedo-Alvarez,G., Saldana,S. and Barcelo,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-OCT-2019) Ingenieria Genetica, Cinvestav, Libramiento
            Norte Carretera Irapuato Leon Kilometro 9.6, Carr Panamericana
            Irapuato Leon, Irapuato 36824, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2013
            Assembly Method                   :: A5-miseq v. 2013
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/16/2023 02:51:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,653
            CDSs (total)                      :: 5,545
            Genes (coding)                    :: 5,358
            CDSs (with protein)               :: 5,358
            Genes (RNA)                       :: 108
            rRNAs                             :: 8, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1 (5S, 23S)
            partial rRNAs                     :: 4, 3, 1 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 187
            CDSs (without protein)            :: 187
            Pseudo Genes (ambiguous residues) :: 0 of 187
            Pseudo Genes (frameshifted)       :: 78 of 187
            Pseudo Genes (incomplete)         :: 114 of 187
            Pseudo Genes (internal stop)      :: 56 of 187
            Pseudo Genes (multiple problems)  :: 47 of 187
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:06:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 94403
            Orig. end                         :: 119641
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WBPF01000021.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..25238
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25238
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25238
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15238](-)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..15238)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            complement(17..865)
                     /locus_tag="F8162_RS22315"
                     /old_locus_tag="F8162_22305"
     CDS             complement(17..865)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000617036.1"
                     /locus_tag="F8162_RS22315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22305"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_151630441.1"
                     /transl_table=11
                     /translation="MIQYKRCSEVSVDLVYEAFKDGFSDYIIKMEVSKEDFIKRFFGPE
                     GNSLKHSFLAVDGKKSVGVILGGIKDYENIKTMRCGTLAVHPNYRGIGVSQKLFELHKE
                     EALQNECKQLFLEVIVGNDRAIHFYTKLGYEKVYDLFYYNLKDLTRIITKDCKGIEVKQ
                     LDFPSFKLEIQKWLHFHINWQNDMDYIEKSNNTFYGAYVDNDLKGSICVNEQGKISFLF
                     VDKDYRNRGIGSKLLQVARENLNVSSLSIGFPNNNLLEGFLKKTGFEKNSLAQYEMYIL
                     L"
     gene            complement(964..1599)
                     /locus_tag="F8162_RS22320"
                     /old_locus_tag="F8162_22310"
     CDS             complement(964..1599)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004394023.1"
                     /locus_tag="F8162_RS22320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22310"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_151630440.1"
                     /transl_table=11
                     /translation="MESTNKIAILGANGKAGKFLVNEVLEKGYQVKILTRNSNNIKITN
                     ENLEIINGDARDFTSIRKLLKGCRAVINAVGQPKNESYIFSTVTKHILEAMKEFEIKRY
                     IVISGGSLNVTGDQKGIANKIGATLFKVFLSKMMQDKYKELQIIQSSEVDWTIVRLPFV
                     IEGNGIGNIKESLVDMPGIKIQNGDIAPFVIKQINSDRYVGRCPFISN"
     gene            complement(1615..2352)
                     /locus_tag="F8162_RS22325"
                     /old_locus_tag="F8162_22315"
     CDS             complement(1615..2352)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129475.1"
                     /locus_tag="F8162_RS22325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22315"
                     /product="S-adenosylhomocysteine nucleosidase"
                     /protein_id="WP_151630519.1"
                     /transl_table=11
                     /translation="MTIGEVKRVMKRIAIVAAWEPELMYLHQCYPSERIEKRAAWEFHF
                     HYINNLEIISVITGVGKVSCASCVQLLISVFQPDELFMTGICGSLSNKVKNGHIVVALN
                     AIQHDVTAAGSGEDIFNLYNGRTAPIETTKSLVRRIKKIRSYDPIHYGTFLSGDQRIRS
                     SEMRYLLHTVYGALAVDQEVAAFAYVCQINNKPFLSLKAASDQANDKTKEEQKIYKMLA
                     CERACEHLIAFLRVHEINVVNNR"
     gene            complement(2352..3026)
                     /locus_tag="F8162_RS22330"
                     /old_locus_tag="F8162_22320"
     CDS             complement(2352..3026)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002110027.1"
                     /locus_tag="F8162_RS22330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22320"
                     /product="DUF3885 domain-containing protein"
                     /protein_id="WP_151630439.1"
                     /transl_table=11
                     /translation="MRLKEYVNQTFPGVTLVPHIHFQWENHLHFHFGKGKDLYVERTED
                     VNREYFTQLYTYNKYLFKDIFSKEDEVFLVTNVYRFKKENVKKSQKINVYNRFIKKRDL
                     KIQIRLETLPFLFEDEEADLYCTYQFSLKCFASDIKYIPLIQAANHEDFPGLYPRFGSK
                     KEISYPDVFLINVTKDIIMFIYDDRGCEVIAKNKETIRNLYEKYKEWIPDYEREGIDKV
                     FT"
     gene            complement(3040..3648)
                     /gene="yqeK"
                     /locus_tag="F8162_RS22335"
                     /old_locus_tag="F8162_22325"
     CDS             complement(3040..3648)
                     /EC_number="3.6.1.41"
                     /codon_start=1
                     /gene="yqeK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000965880.1"
                     /locus_tag="F8162_RS22335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22325"
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="WP_151630438.1"
                     /transl_table=11
                     /translation="MLYKNIYSFIPTGKIENDIKDFLLKYNKELTYKHSIRVANEARKI
                     AVKYYVNEEKAAIAGYLHDISAIFPNEDRIAVAEQFGIEILQEEREFPLIIHQKLSEVI
                     AKEIFKVEDEEILNAICCHTTLRKHATKMDLVLFVADKLEWDQNGTPPYLVEIKKGLKK
                     SLEHAAFAYISYLWDREDTLKVLHPWLEDAYWQLKEIVE"
     gene            3841..4536
                     /locus_tag="F8162_RS22340"
                     /old_locus_tag="F8162_22330"
     CDS             3841..4536
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanR"
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001038809.1"
                     /locus_tag="F8162_RS22340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22330"
                     /product="response regulator transcription factor"
                     /protein_id="WP_151630437.1"
                     /transl_table=11
                     /translation="MNKNILIIDDDKEIVELLAVYLRNEGYNIYKAYDGDEALQMISTY
                     EVDLMVLDIMMPKRNGLEVCQEVRENNTVPILMLSAKAEDMDKILGLMTGADDYMIKPF
                     NPLELVARVKALLRRSSFQNSTSQKNEDGIIHIRSAEIHKHNHTVKVNGEYIKLTSIEF
                     DILHLLASNTGRVFSSEEIFERVWNEDGYGSNKTVMVHISNLRDKLETGMNGEKFIHTV
                     WGVGYKIEK"
     gene            4526..5683
                     /locus_tag="F8162_RS22345"
                     /old_locus_tag="F8162_22335"
     CDS             4526..5683
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="resistance (resist) vanS"
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016129473.1"
                     /locus_tag="F8162_RS22345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22335"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_151630436.1"
                     /transl_table=11
                     /translation="MRNEAFDILKDIPKWKLIFWFMLAITLTPITELIVYRLVTSVIES
                     SLTLSELGKEFIRIFGYEKYKGIKESLWMMIVSYLFLFSIFSSYLYIFYRHERKLYYET
                     CIKKMIEEIRYIANGNFNHKVSIVNHNYLEELASGVNHIVEQLKVSIDEERQAEQAKSE
                     LITNVSHDLRTPLTSIVGYVNLIHHDNYRDEVELRHYIQVIYDKVTRLNALMNDLFEYT
                     RVQNKELSLYSAPIDIVELLGQLTVQFRIQFQEANIECRPSFPSQKLMVLADGDKLVRV
                     FENLIINAIAYGNDGEYIDITVYESNNMIAIDITNYGQPIPSTDLPHIFERFYRVEKSR
                     STNTGGSGLGLAIAKSIVELHKGTIEVYSDDKKTTFTVKLQQYKC"
     gene            5865..6881
                     /locus_tag="F8162_RS22350"
                     /old_locus_tag="F8162_22340"
     CDS             5865..6881
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001160038.1"
                     /locus_tag="F8162_RS22350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22340"
                     /product="D-alanyl-D-alanine carboxypeptidase family
                     protein"
                     /protein_id="WP_151630435.1"
                     /transl_table=11
                     /translation="MQFLKKFTILLLSFVITALIVLYFYLYVNGPIIQAKSAILIDANS
                     GEVVYKKNEEIPIQSATLSKLMTEYIVMEQLNEGKIQLDESVKISNEVFRAETSPIQVT
                     SKDKTTVRDLLHALFLTGNNRSALALAEHIAGNEDNFTLLMNEKAKQLKLSQPSPFLNA
                     TGMNNDTNKQSNTTAIDVAKLATQLVKDFPDVLNITKLTSYQFTFKDSKVFNTNKMIYS
                     LNKNINLQGVDGLQTSFSTNGNYSFVSTAHRGDTRLISVILDSNEENSTFIETKKLLQY
                     GFDPSSYSALQAFKDAVTSWTVLLQFKNLIIQTLLIFFIITILMFLHIRQKKSEDFN"
     gene            complement(6945..7397)
                     /locus_tag="F8162_RS22355"
                     /old_locus_tag="F8162_22345"
     CDS             complement(6945..7397)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288270.1"
                     /locus_tag="F8162_RS22355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22345"
                     /product="DinB family protein"
                     /protein_id="WP_151630434.1"
                     /transl_table=11
                     /translation="MYTLFQYNWQVRDDWFKWCEQLSEEELLRKRVGGVGSILETLFHI
                     VDVEYSWISALQGKEDNEPQFKDYRSIQKVKTLSDLYKRELDDFLQLWSSSLECKILKA
                     SWTNKTYTYGEVLRHVIVHEIHHIGQLSIWARELNLQPVSANLIGR"
     gene            complement(7410..8138)
                     /locus_tag="F8162_RS22360"
                     /old_locus_tag="F8162_22350"
     CDS             complement(7410..8138)
                     /NRPS_PKS="Domain: Abhydrolase_1 (27-133). E-value:
                     6.8e-16. Score: 50.5. Matches aSDomain:
                     nrpspksdomains_F8162_RS22360_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000237666.1"
                     /locus_tag="F8162_RS22360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22350"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_151630433.1"
                     /sec_met_domain="PF00561 (E-value: 5.2e-12, bitscore: 41.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 5.9e-10, bitscore:
                     35.9, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKCIEEYVQVDDFKMYTKKFQGKKRQPVIIMEAGYGDYSKAWDH
                     IAEELTEYGTVLTYDRAGLGKSGKSSKRHISSEMVKDLRSCLAQLQLKPPYIFVGHSFG
                     GINARLFATSYPEDMLGIVLVDSTPENYKVDFLQIMSPEFQEAYYKQFVHESSYEEFMF
                     SLGEADKHCQSMRNIPLVVLAAGKKAFYSSDAQMKWLQLQEELLRLSSNNKFVIAKQSG
                     HYIQKDEPYYVIDAVKWIIG"
     aSDomain        complement(7740..8057)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8162_RS22360_Abhydrolase_1.1"
                     /evalue="6.80E-16"
                     /label="F8162_RS22360_Abhydrolase_1.1"
                     /locus_tag="F8162_RS22360"
                     /protein_end="133"
                     /protein_start="27"
                     /score="50.5"
                     /tool="antismash"
                     /translation="PVIIMEAGYGDYSKAWDHIAEELTEYGTVLTYDRAGLGKSGKSSK
                     RHISSEMVKDLRSCLAQLQLKPPYIFVGHSFGGINARLFATSYPEDMLGIVLVDSTPEN
                     YK"
     CDS_motif       complement(7821..7856)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F8162_RS22360_0001"
                     /evalue="5.50E-05"
                     /label="NRPS-te1"
                     /locus_tag="F8162_RS22360"
                     /protein_end="106"
                     /protein_start="94"
                     /score="15.7"
                     /tool="antismash"
                     /translation="PYIFVGHSFGGI"
     gene            complement(8131..8691)
                     /locus_tag="F8162_RS22365"
                     /old_locus_tag="F8162_22355"
     CDS             complement(8131..8691)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001036630.1"
                     /locus_tag="F8162_RS22365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22355"
                     /product="hypothetical protein"
                     /protein_id="WP_151630432.1"
                     /transl_table=11
                     /translation="MNKKTKVISVAAVSGGGKTTVTERLTQKLTNSKALYFDSYHFENC
                     PADICKWIDDGANYDEWVLTPLIHDIQHLLRDGNVDYLIVDYPFAYLNSEMREFIDATI
                     FIDTPLDIAMARRILRDFKEDTIDEIHNDLKHYMTFARKAYLEAIRTVKPNSDIVLDGS
                     LSVSEIMNHAVEELGRREVIVND"
     gene            complement(8741..9283)
                     /locus_tag="F8162_RS22370"
                     /old_locus_tag="F8162_22360"
     CDS             complement(8741..9283)
                     /EC_number="2.-.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003157550.1"
                     /locus_tag="F8162_RS22370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22360"
                     /product="GNAT family protein"
                     /protein_id="WP_151630431.1"
                     /transl_table=11
                     /translation="MMYERSMKVIKLETFKKSDFKQLINWIDSEEFLIQWSGNSFTYPL
                     NEQQLEKYIESTNTLAFKVIDEETKEVVGHISLGQIDNINKSARIGKVLVGDTKMRGRS
                     IGKHMMKAVLQGAFEELKLHRVTLGVYDFNTSAISCYEKIGFVKEGLLRESKKVGEAYW
                     NLWEMSMLEYEWSDKKQ"
     gene            complement(9397..9711)
                     /gene="exsK"
                     /locus_tag="F8162_RS22375"
                     /old_locus_tag="F8162_22365"
     CDS             complement(9397..9711)
                     /codon_start=1
                     /gene="exsK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002085436.1"
                     /locus_tag="F8162_RS22375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22365"
                     /product="exosporium protein ExsK"
                     /protein_id="WP_151630430.1"
                     /transl_table=11
                     /translation="MIYRSSNYRKKCTCKPNDCWHVFEECKKEHEEQNKPCDCCCVPGI
                     RDELKKLVNRAARITTVGNNYEGTVYSVTCDVVKLANSAGVVTVIISVCNIEAIEPLLT
                     "
     gene            complement(10001..11941)
                     /locus_tag="F8162_RS22380"
                     /old_locus_tag="F8162_22370"
     CDS             complement(10001..11941)
                     /NRPS_PKS="Domain: AMP-binding (98-521). E-value: 1.9e-82.
                     Score: 268.9. Matches aSDomain:
                     nrpspksdomains_F8162_RS22380_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017560287.1"
                     /locus_tag="F8162_RS22380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22370"
                     /product="AMP-binding protein"
                     /protein_id="WP_151630429.1"
                     /sec_met_domain="AMP-binding (E-value: 7.5e-88, bitscore:
                     290.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQAVWFPTEEYKEKTRLYGWMKSLGYEDYETFYNKSIEETAWFW
                     GEAEKAVGYQWMKPYTDVLDLENGTPFAQWYNGGTCNVVESVLSRWLADDETRMQPALQ
                     YEGENGTSKSFTYEELDSWVSRVANGLRHAGIEKGDRVTIYMPMIPETVVAMLAVMKIG
                     AIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKVVSLKDEVDKACEHCPTVEKV
                     VIVRHAGNEFTPHNYDFSWSTLEKEKPCVHAEEMHSDDPLMLIYTSGTTGKPKGTVHTH
                     AGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLFGSLINGATMVMYEGVPDFPK
                     ADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSLKSLEVFASTGEPWNPDPWMW
                     LFETVGKSNVPICNYSGGTEISGGIFGNVLIKPIAPISFNASLPGMAAVVLDDQGNPIR
                     DEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWVHGDWVIYDGEQYIITGRSDD
                     TLNIAGKRIGPAEYESILVKHIDVIEAAAIGVPDEVKGEVCHCFVVLRDNVTFTVELKK
                     ELMSLVNSHIGKALCPKDIHVVEDLPKTRNSKVMRRVIKAAYLGKELGDLSSLVNPEVV
                     PFIEGLQSSKL"
     CDS_motif       complement(10346..10408)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F8162_RS22380_0002"
                     /evalue="7.80E-04"
                     /label="NRPS-A_a8"
                     /locus_tag="F8162_RS22380"
                     /protein_end="532"
                     /protein_start="511"
                     /score="12.3"
                     /tool="antismash"
                     /translation="TGRSDDTLNIAGKRIGPAEYE"
     aSDomain        complement(10379..11647)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8162_RS22380_AMP-binding.1"
                     /evalue="1.90E-82"
                     /label="F8162_RS22380_AMP-binding.1"
                     /locus_tag="F8162_RS22380"
                     /protein_end="521"
                     /protein_start="98"
                     /score="268.9"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="MQPALQYEGENGTSKSFTYEELDSWVSRVANGLRHAGIEKGDRVT
                     IYMPMIPETVVAMLAVMKIGAIISPIFSGFASDAVMTRVQAAGSKMIITADGFSRRGKV
                     VSLKDEVDKACEHCPTVEKVVIVRHAGNEFTPHNYDFSWSTLEKEKPCVHAEEMHSDDP
                     LMLIYTSGTTGKPKGTVHTHAGFPLKAAFDAGFGMNIKQGDRVLWVTDMGWMMGPFLLF
                     GSLINGATMVMYEGVPDFPKADRLWETVDKYEITHLGISPTLIRALMAKGDEYVNKHSL
                     KSLEVFASTGEPWNPDPWMWLFETVGKSNVPICNYSGGTEISGGIFGNVLIKPIAPISF
                     NASLPGMAAVVLDDQGNPIRDEVGELCLEKPWVGMTKSFWEDDERYVNTYWSRFENKWV
                     HGDWVIYDGEQYIITGRSDDTLNI"
     CDS_motif       complement(11099..11155)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F8162_RS22380_0001"
                     /evalue="7.60E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="F8162_RS22380"
                     /protein_end="281"
                     /protein_start="262"
                     /score="24.7"
                     /tool="antismash"
                     /translation="MLIYTSGTTGKPKGTVHTH"
     gene            complement(11990..13531)
                     /locus_tag="F8162_RS22385"
                     /old_locus_tag="F8162_22375"
     CDS             complement(11990..13531)
                     /EC_number="6.-.-.-"
                     /GO_function="GO:0016874 - ligase activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012094296.1"
                     /locus_tag="F8162_RS22385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22375"
                     /product="acyl-CoA carboxylase subunit beta"
                     /protein_id="WP_151630428.1"
                     /transl_table=11
                     /translation="MLDQKHQSNTFEERVETIKQGGAPKYHEQNKAKGKLFVRDRLTLL
                     FDNGEYVEDALFANCEQTGLPADGVITATGKIHGRTACVMANDSTVKAGSWGARTVEKI
                     LRIQETAEKLRVPLFYLVDSAGARITDQVEMFPGRRGAGRIFYNQVKLSGKVPQVCLLF
                     GPSAAGGAYIPAFCDVVMMVEGNASMYLGSPRMAEMVIGEKVTLEEMGGARMHCSVSGC
                     GDVLCKTEEDAITQARQYISYFPNNYLEKTPLVTPQEPKQFDKTLEQIIPENQNAPFNM
                     KDLINRVIDEGSFYEVKKLFAQELITGLARIDGKPVGIIANQPRMKGGVLFHDSADKAA
                     KFINLCDAYHIPLLFLADVPGFMIGTKVERAGIIRHGAKMISAMSEATVPKISIVVRKA
                     YGAGLYAMAGPAFEPDCCLALPTASIAVMGPEAAVNAVYANKIAALPEEERDSFIAEKR
                     EEYKKDIDIYHLASEMVIDGIVHPNNLREELKGRFEMYMSKYQVFTDRKHPVYPV"
     gene            complement(13534..14322)
                     /locus_tag="F8162_RS22390"
                     /old_locus_tag="F8162_22380"
     CDS             complement(13534..14322)
                     /EC_number="4.2.1.17"
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: ECH (14-254). E-value: 6.5e-75. Score:
                     243.5. Matches aSDomain:
                     nrpspksdomains_F8162_RS22390_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001990763.1"
                     /locus_tag="F8162_RS22390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22380"
                     /product="enoyl-CoA hydratase"
                     /protein_id="WP_151630427.1"
                     /transl_table=11
                     /translation="MLQLQNISVDYVTPQVVKISLNRERQANSLSLALLEELQNLLTQI
                     NEESNIRVVILTGAGEKAFCAGADLKERAGMNEEQVRHAVSMIRSTMEMVEQLPQPVIA
                     AINGIALGGGTELSLACDFRIASGTASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKEL
                     IYTGRRISAQEAKEYGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQA
                     DLHTGLQMEKQAYEGVIHTKDRLEGLQAFKEKRTPMYKGE"
     aSDomain        complement(13561..14280)
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F8162_RS22390_ECH.1"
                     /evalue="6.50E-75"
                     /label="F8162_RS22390_ECH.1"
                     /locus_tag="F8162_RS22390"
                     /protein_end="254"
                     /protein_start="14"
                     /score="243.5"
                     /tool="antismash"
                     /translation="QVVKISLNRERQANSLSLALLEELQNLLTQINEESNIRVVILTGA
                     GEKAFCAGADLKERAGMNEEQVRHAVSMIRSTMEMVEQLPQPVIAAINGIALGGGTELS
                     LACDFRIASGTASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKE
                     YGLVEFVVPAHLLEEKAIEIAEKIASNGPIAVRLAKEAISNGIQADLHTGLQMEKQAYE
                     GVIHTKDRLEGLQAFKEK"
     gene            complement(14327..15238)
                     /gene="mvaB"
                     /locus_tag="F8162_RS22395"
                     /old_locus_tag="F8162_22385"
     CDS             complement(14327..15238)
                     /EC_number="4.1.3.4"
                     /codon_start=1
                     /gene="mvaB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017149491.1"
                     /locus_tag="F8162_RS22395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22385"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_151630426.1"
                     /sec_met_domain="HMGL-like (E-value: 9.1e-48, bitscore:
                     158.8, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLPNFAVIKEVGPRDGLQNEKKIVGTKDKVKWIQLLTEAGLSYV
                     EVSSFVHPKWVPALADANDVFSELKRDPNVTYAALVPNQNGLERAFLQNVDEVNVFLSA
                     SESHNKSNINKSIKEALVVIEDITKQALFEGKKVRGYVSTVFGCPYEGDISATAVDELC
                     NQLFSYGIYEVSLGDTIGVANPLQVERVLEHLLKKYDASQFAMHFHNTYGMALANVVKS
                     LEYGITTYDSSCGGLGGCPYAPGASGNVATDDLVHMLHKLGVQTNIDEEKLLRASQFIQ
                     SKLNIQLPSHVYRALQHKTISR"
     gene            complement(15260..15475)
                     /locus_tag="F8162_RS22400"
                     /old_locus_tag="F8162_22390"
     CDS             complement(15260..15475)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001987345.1"
                     /locus_tag="F8162_RS22400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22390"
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein subunit"
                     /protein_id="WP_001985297.1"
                     /transl_table=11
                     /translation="MMTKVYASMAGNVWKIVVGVGDTVEEEQDVVILESMKMEIPIVSE
                     EAGTVMKINVQEGDFVNEGDVLLEIE"
     misc_feature    complement(15499..15515)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 25.24"
                     /tool="antismash"
     gene            complement(15502..16839)
                     /locus_tag="F8162_RS22405"
                     /old_locus_tag="F8162_22395"
     CDS             complement(15502..16839)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Dala_Dala_lig_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RimK"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000486723.1"
                     /locus_tag="F8162_RS22405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22395"
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="WP_151630425.1"
                     /sec_met_domain="Dala_Dala_lig_C (E-value: 4.6e-11,
                     bitscore: 38.3, seeds: 12, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp_3 (E-value: 7.5e-07, bitscore:
                     25.1, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="RimK (E-value: 8.1e-07, bitscore: 24.6,
                     seeds: 4, tool: rule-based-clusters)"
                     /sec_met_domain="ATP-grasp (E-value: 6.4e-10, bitscore:
                     34.6, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQKILIANRGEIAVRIMKTCQKLGIRTVAIYSEADENALHVKMA
                     NEAYLVGGPRVQESYLNLEKIIEIAKKTNAEAIHPGYGLLSENPSFPVRCREEGIVFIG
                     PSEEIITKMGSKIESRIAMQAADVPVVPGITSNIETAEEAIEIAKQIGYPLMLKASAGG
                     GGIGMQLMETEQTLTKAFESNKTRAQNFFGNGEMYLERYIADAHHIEIQLLADTHGNTV
                     YLWERECSVQRRNQKVIEEAPSPFLDEGTRKAMGEVAVQAAKALGYTNAGTVEFLVDDQ
                     QNFYFLEMNTRLQVEHPVTEEITGLDLVEQQLLIAHGEKLSFTQDDVKRSGHAIEARIY
                     AEDPKTFFPSPGKITGLTLPINVRIDHFLENQVTITPFYDPMIAKVIAHGETREEAISK
                     LHDALEELKVEGIKTNTPMLLQVLEDDVFKSGIYTTGFVTKQLVKK"
     gene            complement(16855..18000)
                     /locus_tag="F8162_RS22410"
                     /old_locus_tag="F8162_22400"
     CDS             complement(16855..18000)
                     /EC_number="1.3.99.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001980414.1"
                     /locus_tag="F8162_RS22410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22400"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_151630424.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.8e-40, bitscore:
                     133.9, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 9e-27, bitscore:
                     88.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.2e-57, bitscore:
                     190.1, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFTLTREKQMIKEMVRDFAEKEIAPKAVYYDKTGEFPYETFQKM
                     GELGLLGIPFPEEYGGSGGDTVSYALAVEEIGRACGGTGLSYAATISLGASPIYYFGTE
                     EQKQKYLVPMASGKTLGAFGLTEPNAGSDAGGTQTKAVLDGDEYVISGEKCWITNAEYA
                     NTIIVTAINGVEDNGRKRISAFIVPTTSEGLTISSPYDKMGVRASNTCEIVLDGVRVPK
                     ENILGDVNKGFKQFLYTLDGGRISIAALAVGIAQSAFERALQYAKERQQFGKSISNFQA
                     IQFKLADMATEVELARNLVHKAAWLKDNDKPFGKEAAMAKLFASEAASRIANQAVQIHG
                     GYGYMREYEVERHIRDAKLLEIGEGTSEIQRLVIARHLGCR"
     gene            complement(18217..19185)
                     /locus_tag="F8162_RS22415"
                     /old_locus_tag="F8162_22405"
     CDS             complement(18217..19185)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001248633.1"
                     /locus_tag="F8162_RS22415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22405"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_151630518.1"
                     /transl_table=11
                     /translation="MRQFAKPKIVVSKCLEFDACRYNGEMIPDVTIRNLQPFVTFIPVC
                     PEVEIGLGTPRETIRIVEEKGVNKLVQPSTREDVTEKMEQFSNGFLQTLPDVDGFILKN
                     RSPSCGTRDVKIYSGFEKAPAKGKGSGLFGGAVIKKFSHLPIEEEGRLSNFIIREHFFT
                     RLFTIAHYKMIKHTKNIKELVSFQSDYKYLFMAYNQVKQKELGRIIANQKNETIEVVFD
                     KYEKTLYELFMRTPRYTSNVNVCEHIFGYFKTKLKKQEKDHFLDLIQKYIEKKVPLSSL
                     LTILKSWAIRFDEKYLLRQTYFEPYPEALVEISDSGKGRDY"
     gene            complement(19190..19843)
                     /locus_tag="F8162_RS22420"
                     /old_locus_tag="F8162_22410"
     CDS             complement(19190..19843)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001168189.1"
                     /locus_tag="F8162_RS22420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22410"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151630423.1"
                     /transl_table=11
                     /translation="MKKDWLEELIAATNTDKRNERQMRILEAAVDMFGEKGYAATSTSE
                     IAKRAGVAEGTIFRYYKTKKDLLLAVVMPTLTKFAAPFFVQAFAKEIFKSEYESYEGLL
                     RVVIHNRFEFAKKHFPMIKILIQEVPFQPELKNEIQHLVETELLSHFKKLIVKFQEEGE
                     IIEIPPSSVLRLTLSAVLGLLLTRFLLLPEEKWNDELEIENTIQFILYGLTPRR"
     gene            complement(19868..20887)
                     /locus_tag="F8162_RS22425"
                     /old_locus_tag="F8162_22415"
     CDS             complement(19868..20887)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002161721.1"
                     /locus_tag="F8162_RS22425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22415"
                     /product="ABC transporter permease"
                     /protein_id="WP_151630422.1"
                     /transl_table=11
                     /translation="MRVTGVIIRIIRQFFRDKRSLAMMFGAPMLLLWLLSLVFTQKDYV
                     PHIAVVDVPAPIVKTMKTQEASIYEYGKEKAISELEQQKVDAVIYLENGKMKLLLEGSD
                     SSKNRAVLQVLQKSTEKSDVSVMKPEVNYLHGTKDFTMFDGLGPVLIGFFTFFFVFILS
                     GVSFVRERLSGTLERLLSTPIKRWEIVVGYIIGFGIFAFIQSIIIVNFSVYILDLYVAG
                     SIWLTLLITCMLSLTALTLGTFLSAYANNEFQMIQFIPLVIVPQIFFSGLFPIESMNKW
                     LQMLGKLFPLTYGADAMRQVMIRNQGFTEIALDLTVLLLFSLLFAIGNVFALKKHRKI"
     gene            complement(20884..21609)
                     /locus_tag="F8162_RS22430"
                     /old_locus_tag="F8162_22420"
     CDS             complement(20884..21609)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016087811.1"
                     /locus_tag="F8162_RS22430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22420"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151630421.1"
                     /transl_table=11
                     /translation="MQQPAIILRTVSKSLGKKEVLHNLSLQVEKAEIFGLVGPSGSGKT
                     TLIKLIAGINEATEGEVFVYNTNMPNLNEMKRIGYMAQADALYEELSAYENADFMATMY
                     GLKGKHKKERIEEVFALVQLSQHMKKQVQHFSGGMKKRLSLAIALLHEPEILILDEPTV
                     GIDPLLRKTIWEKFYNLKKKGTTIIVTTHIMDEAEYCERLGLIREGKLVATGTPEELKK
                     RVSSGRIEDVFLLEEVALS"
     gene            complement(21799..22050)
                     /locus_tag="F8162_RS22435"
                     /old_locus_tag="F8162_22425"
     CDS             complement(21799..22050)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000548597.1"
                     /locus_tag="F8162_RS22435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22425"
                     /product="hypothetical protein"
                     /protein_id="WP_063224861.1"
                     /transl_table=11
                     /translation="MHKEYEIEEYTAIEEQIHYYYKCLLVSHPDQIIKYLEKRLEKYAE
                     TLQYAHLYPDTVILPLQQLVIEYSLDVARIRKYMNLKT"
     gene            complement(22262..23102)
                     /locus_tag="F8162_RS22440"
                     /old_locus_tag="F8162_22430"
                     /pseudo=""
     CDS             complement(22262..23102)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002141840.1"
                     /locus_tag="F8162_RS22440"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22430"
                     /product="metallophosphoesterase"
                     /pseudo=""
                     /sec_met_domain="Metallophos_2 (E-value: 3.3e-10, bitscore:
                     36.0, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKKTKRIILLISILVSFSIFLYSQNNLISITEVNITSNKIPSSF
                     KGFKILQISDLHNKKFGDNQETLIQKVKSINPDIIAITGDLIDSKSYDAEVSMELIREL
                     VKEYPVYFVTGNHEKWSEKYNDLEKELKKHHVTVLRNEHVTIQKEEQKINLLGIDDPEF
                     VTGNRDEGNIVKDEIIKAKIEIQADTYNVLLSHRPEFLAKYADEQIDLVLSGHAHGGQV
                     RLPFIGGLVAPNQGIFPTYTAGLYEKKYVYGSK"
     misc_feature    complement(23147..23165)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 22.89"
                     /tool="antismash"
     misc_feature    23419..23432
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: strong, score: 24.21"
                     /tool="antismash"
     gene            23747..24316
                     /locus_tag="F8162_RS22445"
                     /old_locus_tag="F8162_22435"
     CDS             23747..24316
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000782792.1"
                     /locus_tag="F8162_RS22445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_22435"
                     /product="hypothetical protein"
                     /protein_id="WP_002065511.1"
                     /transl_table=11
                     /translation="MKMKRKIMMTTALAATLATGALPTTSVFAAEKEAPIQQKEAQMSI
                     QPFAQNNLETAVKAALNGPEVKKIKVFEHEFNVKPIEVVNLGGGKTYVKGQISHHLSFR
                     PDDQFYYEFTVQDGKVIDKPVFNIDRGGWTPFAAPLLSILAAYNGIPVNPNDLNALGQQ
                     IGKVIDGSWEHAAQSIATVVSLSFNE"
ORIGIN
        1 taactcctcc caccttttat agcaatatat acatttcata ttgtgctaat gagttctttt
       61 caaatccagt tttctttaaa aatccttcta gtaaattgtt gtttggaaac ccaatggata
      121 aacttgatac atttaagttt tctcttgcca cttgtaataa ttttgatcca ataccacgat
      181 ttctatagtc tttgtctacg aaaagaaaac taattttacc ttgttcattc acacatatag
      241 aaccctttaa atcattatcg acatatgcgc cgtaaaatgt attatttgat ttttcgatat
      301 aatccatatc attttgccaa tttatatgga aatgcaacca tttctgtatt tcaagtttaa
      361 acgatggaaa atctaattgt tttacttcaa ttcccttaca gtctttagtt attatcctag
      421 tcaaatcttt taaattataa taaaatagat cgtacacttt ttcatagcct aatttcgtat
      481 aaaaatgaat cgctcggtca tttcctacaa tgacttcaag gaaaagttgc ttacactcat
      541 tttgaagcgc ctcttcttta tgtagttcaa ataacttttg actcacacca ataccacggt
      601 aatttggatg aacggctaat gttccacagc gcattgtttt tatgttttca taatccttta
      661 tcccgccaag tattacacca acagatttct taccgtctac ggcaagaaag gaatgtttaa
      721 gtgaattccc ttctggccca aaaaaccttt ttataaaatc ttcttttgaa acttccattt
      781 taataatgta atctgaaaat ccatctttaa atgcttcata tactaaatct acacttactt
      841 cactgcacct tttgtattga atcatataaa attatccccc acttactcgt tttaaactta
      901 acattcaaat acataaaata tactagttcc atcctaccca acattcttta atttttatac
      961 cacttaattt gaaatgaacg gacacctccc cacatatcta tcactattaa tttgttttat
     1021 aacaaacggt gcaatatccc cattttgtat tttgattcct ggcatatcaa ctaaactctc
     1081 ttttatattt ccaataccat ttccctctat aacaaatggt aatctaacaa ttgtccaatc
     1141 tacttcacta ctttggataa tttgtaattc tttatattta tcttgcatca tttttgataa
     1201 aaaaacttta aataatgtag cccctatttt atttgcaatt cccttttgat ctcctgtaac
     1261 atttaaagaa cctccagaaa ttacaatata tctttttatt tcaaactcct tcattgcttc
     1321 tagaatatgc ttcgttactg tgctaaaaat ataagattca ttttttggtt gacctaccgc
     1381 attaattaca gctcgacacc ctttaagtaa tttgcgtatt gaagtaaaat cacgtgcatc
     1441 tccattaata atctctaaat tttcatttgt tattttgata ttattagaat ttcttgttaa
     1501 tatttttact tgatatccct tttctaacac ttcgtttaca aggaatttcc cagcttttcc
     1561 gtttgcaccc agaatagcta ttttatttgt actttccaat attaacccct cttactatct
     1621 attatttact acattaatct catgtacacg taaaaaagca attaaatgct cgcacgctcg
     1681 ttcacacgct aacattttat agattttttg ttcctctttc gttttatcat ttgcttgatc
     1741 tgatgcagct tttaaactaa gaaaaggttt gttattaatt tgacacacat aagcaaaagc
     1801 tgccacttct tgatcaaccg ctaatgctcc atatacagta tgaagtaaat atctcatttc
     1861 tgaactacgg atacgttggt ctccagataa aaatgtacca taatgaatcg gatcataaga
     1921 tcgtatcttt tttattcttc ttacaagtga ctttgtcgtt tcaataggtg ctgtcctacc
     1981 attatataaa ttaaaaatat cttcccctga accagcagca gtaacgtcgt gttgtattgc
     2041 attaagggct actacaatat gtccattttt caccttattt gatagacttc cacatattcc
     2101 tgtcataaac aactcatctg gctgaaacac actaattaat aattgcacac aactagcaca
     2161 gcttactttg ccaactccag ttataacgga gataatttcc agattattaa tataatgaaa
     2221 atgaaattcc caagctgctc gtttttcaat acgttcactt ggataacatt gatgcaaata
     2281 cataagttct ggttcccatg cggctacgat tgcaatacgt ttcattacac gcttcacttc
     2341 ccctattgtt atcatgtaaa tactttatct ataccttctc gttcataatc tggaatccac
     2401 tctttatatt tctcatataa atttcgtatt gtttctttat tcttcgcaat tacttcacat
     2461 cctctatcat cgtatataaa catgataata tctttcgtta catttataag aaatacatct
     2521 ggataagaaa tttctttttt gcttccaaaa cgaggataaa gacctggaaa atcttcatga
     2581 ttcgcagctt gaataagtgg tatatacttt atatcgctag caaaacattt tagtgaaaat
     2641 tgatatgtac aatataaatc agcttcttca tcttcaaata gaaaaggtaa tgtttctagt
     2701 cttatttgga tttttaaatc cctcttttta ataaatcgat tatatacatt tattttctgc
     2761 gactttttca cattttcctt tttaaatcga taaacatttg ttactaaaaa gacttcatct
     2821 tcctttgaaa atatatcttt aaataagtat ttattatatg tatacagttg agtgaagtat
     2881 tccctattta catcttcggt tctttctaca tataggtctt tccctttccc aaaatgaaaa
     2941 tgcaaatgat tttcccattg aaagtgtata tgtggtacta atgtaacccc aggaaatgtt
     3001 tgattcacat attcttttaa tcgcattctt ataccctttc tactctacaa tttcttttaa
     3061 ctgccaatat gcatcttcta gccacggatg taaaactttc aacgtgtctt ccctatccca
     3121 caaatatgaa atatatgcaa aagcagcatg ttctaaagat ttttttaatc ctttttttat
     3181 ttctactaaa tatggtggtg taccattttg atcccattct aatttatcag caacaaataa
     3241 cactaaatcc attttcgttg catgtttacg tagtgtagta tgacaacata ttgcatttaa
     3301 aatctcttca tcttccactt taaatatctc ttttgcaatt acttccgata acttttgatg
     3361 aataatcagt gggaattctc gttcttcttg taatatctct attccaaatt gctcagcaac
     3421 tgcaatccga tcttcattcg gaaaaattgc actaatatca tgcaaatatc ctgcaattgc
     3481 tgccttttct tcatttacat aatacttaac cgcaattttt cgagcttcat ttgccacccg
     3541 aattgaatgt ttatatgtaa gttctttatt gtattttaat agaaaatctt ttatatcatt
     3601 ttcaattttt ccagttggaa taaatgaata aatattctta tataacatcg taagtcctcc
     3661 ttcttcttaa ctctcaatat aacgttatat ttaaatatcc tttttatttg tattcgttaa
     3721 gaatgtttta atcccttttt tatacgttac atgaaatttt atgtggaatc attgctacaa
     3781 aatacataaa tgtttgatat tatagtaatg ttaatgattt gttaggaaag gaactacata
     3841 atgaataaaa acatattaat tattgatgat gataaagaaa ttgttgaatt acttgctgtt
     3901 tacttacgaa atgagggcta taacatttat aaagcatatg atggcgatga ggcattacaa
     3961 atgatttcta cctatgaagt tgaccttatg gttctagata taatgatgcc aaaacgaaat
     4021 ggattagaag tttgccagga agttcgtgag aataatactg tacctattct tatgcttagt
     4081 gcaaaagcag aagatatgga taaaatatta ggtcttatga caggtgccga tgattatatg
     4141 attaaaccat tcaatccatt agaattagta gctagagtga aagctttact acgaagatca
     4201 tctttccaaa atagcacttc tcaaaagaat gaagatggta ttatccatat tcgttctgct
     4261 gaaattcaca aacataatca tactgttaaa gtaaatggag agtatattaa acttacatct
     4321 attgaatttg atattttaca tttacttgcg agtaataccg gaagagtatt tagttccgaa
     4381 gaaatttttg aacgcgtttg gaatgaagat ggttatggtt caaataaaac tgtaatggtc
     4441 cacataagta atttacggga taaacttgaa acaggtatga atggagaaaa gtttattcat
     4501 actgtttggg gagtaggcta taaaattgag aaatgaagca tttgatatat taaaagatat
     4561 cccaaaatgg aagttgattt tttggttcat gttagccatc acccttaccc ctattactga
     4621 attaattgta tatcgtctcg ttacaagtgt aattgaaagt tcacttacgt taagcgaact
     4681 cggcaaagaa ttcataagaa tttttggtta tgaaaaatat aaaggaataa aggaatctct
     4741 ttggatgatg atcgtctctt atttattttt attttcgatt ttctcatcct acctatacat
     4801 tttttaccgt catgaaagaa agctttacta tgaaacttgt attaaaaaaa tgatagaaga
     4861 gattcgttat attgcaaatg gaaatttcaa tcataaagtt tctatcgtaa accataatta
     4921 tctggaagag ttagcaagtg gggtaaatca cattgttgaa caattgaaag tttcgattga
     4981 tgaagaaaga caggcggaac aggcaaaaag tgaacttatt acaaatgtat cgcatgattt
     5041 acgtactcct cttacctcta tagttggata cgtgaattta atccatcatg ataattatag
     5101 agatgaagtg gaattacgtc attatataca agtcatttac gataaagtaa cacgtcttaa
     5161 tgcattaatg aatgatttgt ttgaatatac acgtgttcaa aataaagagt taagtttata
     5221 ttctgctcct attgatattg tagagctact tggacaatta actgttcaat tccgcattca
     5281 gtttcaagaa gctaatatag aatgtcgtcc ttctttccca tctcaaaaac tcatggtatt
     5341 agctgatgga gacaaattag ttcgcgtatt tgaaaatcta attattaatg ctatcgctta
     5401 cggtaacgat ggtgagtata ttgatattac tgtttatgaa agtaataata tgattgcaat
     5461 tgatataaca aattacggtc aacctattcc tagtacggat ttacctcata tttttgaacg
     5521 tttttatcgc gttgagaaat cacgctctac aaacaccggt ggatctggac tcgggttagc
     5581 aattgcaaaa agtattgtgg aattgcataa aggaacaatt gaagtgtata gtgatgacaa
     5641 aaaaaccact ttcactgtaa aactacaaca atataaatgt taatagagct taactttagg
     5701 tccaattcct tatcatataa ggaattggac ctttcatttt ccattaacat ccaaaattta
     5761 ataatccttt ataattcttt agaaattctt taccttttct ttcttcctaa ttaagcattc
     5821 ctttttacaa tattattatc gatgtcataa taggaggatc gcttatgcaa ttcttgaaaa
     5881 aattcacaat tttattgtta tcttttgtta ttacagcact tatcgtttta tatttttatc
     5941 tttatgtaaa tggtccaatt attcaagcta aatcagctat tttaatagat gctaattcag
     6001 gtgaagttgt ttataaaaaa aatgaagaaa ttcctataca gtcagctact ttatctaaat
     6061 taatgacaga gtatatcgta atggaacaac tgaatgaagg gaaaatacaa ttagatgaat
     6121 cagtaaaaat aagtaatgaa gttttccgag cagaaacgag tcctatacaa gtaacttcga
     6181 aagataaaac gacagttcgt gacttacttc atgcattatt tttgacaggg aataatcgtt
     6241 ccgcacttgc ccttgcagaa cacattgctg gaaacgaaga taactttaca cttttaatga
     6301 atgaaaaagc aaaacaacta aagttatcac aaccatcccc gtttctaaat gctactggta
     6361 tgaataacga tacaaataaa caatcaaata caacagcgat agatgtagcg aaactagcga
     6421 cacaattagt aaaagacttt ccagatgtat taaatattac gaaactaacc tcttaccaat
     6481 ttaccttcaa agattcaaaa gttttcaaca caaataaaat gatttattcc cttaataaaa
     6541 acattaatct ccaaggtgtt gacggcttac aaactagttt ttcaactaat ggtaattata
     6601 gttttgtaag tacagcacat cgaggagata ctagacttat ttctgtaata ttagactcaa
     6661 atgaagaaaa cagtaccttt attgaaacaa aaaagctact acagtacggt tttgatccat
     6721 cctcttactc tgcactccaa gcttttaaag atgctgttac atcttggaca gttttgcttc
     6781 agtttaaaaa tttaatcata caaacattat tgattttctt cattattaca attttaatgt
     6841 ttttacatat acgtcagaaa aaatccgagg atttcaatta ggaaatcttc ttatatatat
     6901 aaaacggctt gcatttacag tacaagccgt ttttttaact ataatcatct tccaattaaa
     6961 ttcgctgaaa caggctgaag atttagttct ctcgcccata tagatagctg accaatgtga
     7021 tgaatttcat gtacaattac atgtcttaac acttcaccat atgtatatgt tttatttgtc
     7081 cacgaagctt ttaatatctt acattctagg ctagatgacc acaactgcaa aaaatcatct
     7141 aattctcgtt tatataaatc agataacgtt ttcacttttt ggattgatcg ataatcttta
     7201 aactgcggtt cattatcttc ttttccttga agtgcgctaa tccagctgta ttcaacatcg
     7261 acaatatgga ataatgtttc taaaatactc cctacaccac ctacacgctt gcggagcaat
     7321 tcttcctctg aaagttgttc acaccactta aaccaatcat ctcttacttg ccaattgtat
     7381 tgaaataatg tgtacatatt tatctctccc tatccaataa tccacttaac cgcatctatc
     7441 acataatatg gctcatcttt ttgaatatag tgaccacttt gttttgcaat tacaaattta
     7501 ttattgcttg ataatcgtaa taattcttct tgcaattgta accatttcat ttgtgcatct
     7561 gacgaataaa aagctttttt acctgcagct aacacgacaa gtggaatatt tctcattgac
     7621 tgacaatgtt tatctgcttc gcctagacta aacataaact cttcatatga actttcatgt
     7681 acaaattgtt tatagtatgc ttcttgaaat tcaggagaca tgatttgcaa aaaatctact
     7741 ttataatttt ctggtgtaga atcgaccaaa actattccta acatatcttc gggataagaa
     7801 gtcgcaaata aacgtgcatt tataccacca aaagaatgtc ctacaaaaat ataaggtggt
     7861 ttcaattgta attgcgctaa gcaacttctt aaatctttta ccatctcaga actaatatgt
     7921 cgcttggaac tcttcccact tttccctaac cccgctctgt catatgtaag taccgttcca
     7981 tattccgtca actcttcagc aatatgatcc catgcctttg aataatcgcc ataacctgcc
     8041 tccattataa taactggctg ccgcttcttt ccttggaact ttttcgtata cattttaaaa
     8101 tcgtcaactt gtacatattc ctctatacat ttaatcattg acaatcactt ctcttcggcc
     8161 aagttcctct acagcatgat tcattatttc acttacagat aaagagccat ccaatacaat
     8221 atccgaattc ggcttaacag tacgaattgc ctctaaataa gcctttctcg caaatgtcat
     8281 ataatgtttt aaatcattat gtatttcatc tattgtatct tctttaaaat ctcgcaagat
     8341 tcttctagcc atcgcaatat ctaaaggcgt atctataaat atagttgcat caataaattc
     8401 tcgcatttca ctatttaagt atgcaaaagg ataatctaca ataagataat ctacatttcc
     8461 atctcgtaat aaatgctgaa tatcatgaat taatggcgta agtacccatt catcataatt
     8521 tgctccatca tcaatccatt tacaaatatc tgcaggacag ttttcaaagt gatagctatc
     8581 aaaatatagt gcttttgaat ttgttagctt ttgagttaat ctttctgtaa cagttgtttt
     8641 acctcctccc gaaacagctg caaccgaaat tactttagtt tttttattca taacttcccc
     8701 accatacccc ttttaattaa cataacataa ttataaaaaa ctattgtttt ttatcgctcc
     8761 attcatattc taacatactc atttcccata aattccaata cgcttctcct actttttttg
     8821 actctcgtaa taaaccttct tttacaaacc ctattttttc ataacatgaa atggccgacg
     8881 tattaaaatc ataaacgcca agagttactc tatgtagttt taattcttca aatgcacctt
     8941 gtagtactgc tttcatcata tgtttcccta tagaacgtcc tcgcattttc gtatcaccga
     9001 ctagtacttt tccaatcctt gcagacttat ttatattgtc tatttgccca agtgaaatat
     9061 gaccaactac ttctttagtc tcttcatcta ttactttaaa tgcaagtgta tttgtgcttt
     9121 ctatatattt ttctaattgc tgttcattta aaggatatgt aaatgaattt cctgaccact
     9181 gtattaaaaa ttcttcggaa tcaatccaat ttattaattg tttgaaatca gactttttaa
     9241 aggtttctag ttttatcact ttcatgctcc tttcgtacat catactttat agcctcgaac
     9301 ttatttctat ataaagaata tattctcctt ttatatgaaa ttaaaataaa gccattctaa
     9361 tgaatggctt tacaaaaaag cataattata ctttccctag gtcaacaatg gttcaatcgc
     9421 ttcaatatta caaacggata ttattactgt aactacccca gcactattag caagctttac
     9481 aacatcacaa gttactgaat aaactgttcc ctcataatta tttcctactg tcgtaatgcg
     9541 cgccgctctg tttactagtt tttttaattc atctctaatt cccggtacac agcaacagtc
     9601 acatggctta ttttgctctt catgttcttt tttacactct tcaaatacat gccaacaatc
     9661 atttggttta catgtacatt tttttctata attactagat ctataaatca caatctcacc
     9721 tccaaactct ttctattaat aaagtatgtc tacgagctta taaatgtact aggtaaatac
     9781 atagaaatcc aaaaacaaac actcgtccta agcgattaaa tacacataaa aacacttgta
     9841 ttgctatgtg aattttcatt ttaaataaat aaagtatatt cattatccat acaaaaatat
     9901 atacaactat tataaatctt ctttttatca ttaattataa tgcaataaaa actgacctct
     9961 aacgattaga ggccagttca tattatacat actttatatc ttataatttg ctagactgta
    10021 acccctcaat aaacggaact acttcagggt ttacaagtga tgataaatca cctaattctt
    10081 ttcctaagta agcagcttta atgacgcgtc gcattacttt agaattacgt gttttcggta
    10141 aatcttctac aacgtgaata tcttttggac ataatgcttt tccaatatga gagtttacta
    10201 aactcattaa ttccttcttt aactctactg tgaatgttac attgtccctt aatactacaa
    10261 aacaatgaca aacttcacct tttacttcat caggtacacc aatcgcggca gcttctatga
    10321 cgtcaatatg ctttacaaga attgattcat attcagcagg tccaatacgt ttcccagcaa
    10381 tgtttaacgt atcatctgag cgtcctgtaa taatatactg ctcaccatca taaataaccc
    10441 agtcaccatg aacccattta ttttcaaaac gtgaccaata tgtgttcaca taacgctcat
    10501 cgtcctccca gaaacttttc gtcataccaa cccaaggttt ctctaaacat aattctccaa
    10561 cttcatcacg aattggatta ccttgatcat cgagcacaac cgctgccatt cctggtaaag
    10621 aagcgttaaa gcttatcggt gcaattggtt taataaggac gtttccgaaa atcccaccag
    10681 aaatttcagt tccgcctgaa tagttacaaa tcggcacatt actttttcca actgtttcaa
    10741 atagccacat ccaaggatct ggattccaag gttcacctgt tgatgcgaat acttctaaac
    10801 tcttaagcga atgtttattt acatactcat cacctttcgc cattaacgca cgaattaatg
    10861 ttggtgatat accaagatgt gtaatttcat atttatcaac tgtctcccat aaacgatctg
    10921 cttttgggaa atccggaaca ccttcataca taaccatcgt cgctccatta atgagtgagc
    10981 cgaatagtaa aaatggtccc atcatccagc ccatatcagt tacccataat acgcggtcac
    11041 cttgttttat attcattccg aaccctgcat caaaagcagc tttcaaagga aatccagcat
    11101 gagtgtgtac tgtccctttc ggttttccag ttgtacctga tgtataaatg agcattaacg
    11161 gatcatcact atgcatttct tcagcatgta cacatggctt ttctttttct aacgtactcc
    11221 atgagaaatc ataattatgc ggtgtaaatt catttcctgc gtgacgcacg ataacgactt
    11281 tttcaacagt tggacaatgc tcacaagctt tatctacttc atcttttaat gaaacaactt
    11341 taccacggcg tgaaaaacca tctgcagtaa tgatcatttt tgatcctgcc gcttgcacac
    11401 gtgtcatgac tgcatcagac gcaaatcctg agaatattgg tgaaataatt gctccgattt
    11461 tcataacagc cagcattgca acaactgttt ctggaatcat cggcatataa attgttacac
    11521 ggtcaccttt ttcaataccc gcatgtctca aaccgtttgc aacgcgactt acccagctgt
    11581 caagttcttc atatgtaaat gattttgaag ttccattttc cccctcatac tgaagtgctg
    11641 gttgcattct tgtttcatca tctgcaagcc agcgtgataa aactgactct acaacgttac
    11701 atgttccgcc attataccac tgtgcaaacg gcgtaccatt ttctaaatct agcacgtctg
    11761 tataaggttt catccattga tagccaaccg ctttctcagc ttctccccaa aaccaagctg
    11821 tttcttcaat agatttatta taaaacgttt cataatcttc atagcccaat gatttcatcc
    11881 aaccatataa acgcgttttt tctttatact cttctgttgg aaaccaaact gcttgtttca
    11941 atgttttccc ctccttgact tttgagcaag aaagccctaa atagggcttt taaactggat
    12001 aaacaggatg tttacgatcc gtaaatactt gatatttact catgtacatt tcgaatcgtc
    12061 cttttaactc ttctcttaaa ttgtttggat gaacaatacc atcaatgacc atctctgatg
    12121 ctaaatggta aatatcaata tctttcttat actcttcgcg tttttcagca atgaagctat
    12181 cacgctcttc ttctggtaaa gctgcaatct tatttgcata tacagcattg accgcggctt
    12241 ctggacccat taccgcaata gaagctgtcg gtaatgcaag gcaacaatct ggttcaaagg
    12301 ctgggcctgc cattgcatat aaaccagcac catacgcttt acgaacaacg atagaaattt
    12361 tcggtacagt tgcttcactc attgcagaga tcatttttgc accgtggcga ataataccag
    12421 cacgctctac ttttgtacca atcataaatc caggtacatc tgcaaggaat aataatggaa
    12481 tatgatatgc atcgcataaa ttaataaact tcgctgcttt atcagctgaa tcgtggaata
    12541 atacgccgcc tttcatacgc ggttgatttg caataattcc aactggctta ccatcaatac
    12601 gtgctaaacc tgtaatgagt tcttgagcaa ataacttttt cacttcatag aaagaacctt
    12661 catcaataac tctattaatg agatctttca tattgaaagg agcattttgg ttttctggaa
    12721 tgatttgttc taacgtttta tcgaattgtt tcggttcttg aggtgtaacc aatggagtct
    12781 tttctaagta gttgtttgga aaatatgaaa tgtattgtct tgcttgcgtt attgcatctt
    12841 cttctgtttt acataaaaca tctccgcatc ctgatacaga gcaatgcata cgagctccgc
    12901 ccatctcttc taaagttacc ttctcaccga taaccatctc agccatacga ggagatccta
    12961 aatacataga tgcatttcct tcaaccatca ttacaacgtc acagaaggct ggaatatatg
    13021 cgccaccagc tgccgaaggt ccaaataata aacatacttg cggaacttta cctgataatt
    13081 tcacttgatt atagaagatt cttcctgcac cgcggcgccc tgggaacatt tcaacttgat
    13141 cagtaatacg cgctccagca gagtcaacta aataaaataa cggaacacgt aatttttctg
    13201 ccgtttcttg aatacgtaaa atcttttcaa ctgtacgtgc accccatgat ccagccttta
    13261 ctgttgaatc atttgccatt acgcatgcag tacgaccatg tattttacct gttgccgtaa
    13321 taacaccatc agcaggtaat cctgtttgtt cacaattggc aaataatgca tcttctacat
    13381 attcaccatt atcaaataaa agagttaagc gatctcgaac gaatagtttt ccttttgctt
    13441 tgttttgttc atgatatttt ggtgcgccgc cttgtttaat cgtttcaact cgttcttcaa
    13501 atgtattcga ttggtgtttt tggtctaaca tatttactcc cccttataca ttggtgtgcg
    13561 tttttcttta aatgcttgta atccttctaa tctatctttc gtatggatta caccttcata
    13621 cgcttgtttt tccatttgta atccggtatg taaatcagct tgaataccgt ttgaaattgc
    13681 ttcttttgct aatcgaacag cgattggacc attactagca attttctctg ctatttcaat
    13741 cgccttctct tcaagtaaat gagctggtac aacaaattct actagaccat attcttttgc
    13801 ttcttgcgcc gaaatacgtc ttcctgtata aattaattct tttgctctac caacaccaat
    13861 taatcttggc aaacgctgcg taccacctgc tcctggtata attgcaagtg tagtttcagt
    13921 aagaccaaga cttgcagtgc ctgaagcaat tctaaaatcg caagctaaac ttaattccgt
    13981 accaccacca agtgcgattc catttatagc agcaataact ggctgtggta attgttcaac
    14041 catttccata gtagaacgaa tcatactaac agcatgacga acttgttctt cattcatgcc
    14101 agcacgttct tttaaatcag caccagcaca aaacgctttt tcaccagcac ctgttagaat
    14161 aactacacga atatttgact cttcatttat ttgagttaat aagttttgta actcttctaa
    14221 taacgctaaa gataatgagt ttgcttgtct ttcacgattt aatgaaatct ttacaacttg
    14281 aggagttaca taatcaactg aaatattttg taattgtagc atcttctcac ctgcttatcg
    14341 ttttatgttg aagcgctcta tacacatgac tcggtaattg gatatttaat ttactttgaa
    14401 taaattgact cgctctcaat aacttctctt catcaatatt cgtttggacc cctaacttat
    14461 ggagcatatg aactaagtca tcagttgcaa catttcctga tgctcccggt gcatatggac
    14521 agcccccaag accaccacaa gagctatcat acgttgtaat accatattct aatgacttca
    14581 ctacattcgc cagagccatt ccatacgtat tatggaagtg cattgcaaac tgcgaggcat
    14641 catatttctt taataaatgt tctaatactc gctctacttg tagcggattc gctacaccga
    14701 tcgtatcccc taatgagact tcataaatgc catatgaaaa tagttgatta cataattcgt
    14761 caactgccgt ggcacttata tctccttcat aaggacatcc aaatacagta gaaacatagc
    14821 ctcttacctt tttcccttcg aataatgcct gttttgttat atcttcaatt acaactaagg
    14881 cttctttaat tgatttatta atattacttt tattatgaga ttcacttgct gataaaaaaa
    14941 cattcacctc atctacattt tgcaaaaaag ctcgttccaa accattttga tttggaacaa
    15001 gcgctgcata agtaacattt ggatcccttt ttagctcaga aaacacatca tttgcatctg
    15061 ctaatgcagg gacccattta gggtgaacga atgaggaaac ttcaacgtac gacaatcccg
    15121 cttctgtaag tagttgaatc cattttactt tatcttttgt gccaacaatc tttttttcat
    15181 tttgtaagcc atcacgtggc ccgacttcct taatgacagc aaaattaggt agtttcaatt
    15241 cgcttccccc tatatctccc tattcaattt ctagtaatac atctccttca tttacaaaat
    15301 cgccttcttg cacattaatt ttcataactg tgccagcttc ttctgaaacg attggaattt
    15361 ccattttcat agattccaaa atgacgacat cctgctcttc ctctactgta tctcctactc
    15421 ctacaacaat cttccataca tttcctgcca tcgatgcata tactttcgtc atcatttttt
    15481 cccccttaat gttgttaaat cttatttttt aacaagttgt ttcgttacaa aacccgttgt
    15541 ataaatacca cttttgaaca catcgtcttc caatacttga agtaacattg gcgtgttcgt
    15601 tttaatacct tctaccttta attcttctaa agcatcatgt aattttgaaa ttgcttcttc
    15661 acgagtttca ccatgagcaa tgacttttgc aatcattgga tcatagaaag gtgtaatcgt
    15721 tacttgattc tccaaaaagt gatcaatgcg tacatttatt ggaagcgtta aacctgtaat
    15781 tttcccaggt gatgggaaga aagttttcgg gtcttctgca taaatgcgcg cctcaatggc
    15841 atgaccacta cgttttacat catcttgtgt aaatgatagt ttctcaccgt gtgcaattag
    15901 aagttgttgt tctacaagat ctaaaccagt aatttcttct gtaactggat gctctacttg
    15961 taatctcgta ttcatctcta agaaatagaa gttctgctga tcatcaacta gaaactcaac
    16021 tgtaccagca tttgtatatc ctagagcttt ggcagcttgt acagcaactt cacccatcgc
    16081 ttttcgtgta ccttcatcta aaaatggtga gggtgcttct tcaatcactt tctgatttcg
    16141 gcgttgtact gaacattcac gctcccataa atacactgtg ttaccatgtg tatctgctaa
    16201 aagctgaatt tcaatatgat gtgcatccgc tatatagcgc tctaaataca tttctccgtt
    16261 accgaagaag ttttgtgctc ttgttttgtt actttcaaat gctttggtga gcgtttgctc
    16321 agtttccatc aactgcattc caatgcctcc gccgcctgcg gatgccttca gcattaatgg
    16381 ataaccaatt tgtttagcaa tttcaattgc ttcttcagct gtttcaatat ttgaagtaat
    16441 acctggaact actgggacat ctgcagcttg cattgcaata cgtgattcga ttttacttcc
    16501 catcttcgta atgatttctt ctgatggacc tataaatacg attccttcct ctctacagcg
    16561 tactggaaaa gacggattct ctgataataa tccatatccc ggatggattg cttcagcatt
    16621 tgtcttctta gcaatttcaa taattttttc aaggtttaaa taactttctt ggacacgagg
    16681 gccacctact aagtaagctt catttgccat ttttacatgt agggcatttt catcagcctc
    16741 agaataaata gcaactgtac gaatgccaag tttttgacaa gttttcataa tacgaactgc
    16801 gatttccccg cgattagcaa ttaatatttt ttgaaacata gtgattcctc ctttttatct
    16861 acatcctaaa tgtcttgcaa ttacgagacg ttgaatttca gaagttcctt caccaatttc
    16921 taatagtttt gcatcacgaa tatgtcgttc cacttcatat tcacgcatat agccgtatcc
    16981 accgtgaatt tgtaccgctt gatttgcaat acgactagca gcttcagatg cgaaaagttt
    17041 tgccatagcc gcttctttac caaaaggttt atcgttatct tttaaccaag ctgctttatg
    17101 tactaaatta cgcgctagct ctacttcagt cgccatatca gctaatttaa attgaatcgc
    17161 ttggaaatta gaaattgact ttccaaattg ttgacgttct ttcgcatatt gcagtgcacg
    17221 ttcaaatgca gattgcgcaa tacctactgc taatgctgcg attgaaatac gtcctccatc
    17281 aagtgtatat aagaattgtt taaatccttt atttacatca ccaagaatat tttctttcgg
    17341 tacacgtaca ccatcaagta cgatttcaca tgtattagaa gcacgaacac ccatcttatc
    17401 gtaaggactt gagatcgtta atccctcact tgtagtcggt acgataaatg ccgaaatacg
    17461 ttttctacca ttatcttcaa caccattgat agcggttaca ataattgtat ttgcatactc
    17521 tgcatttgta atccaacact tttcaccact aataacatat tcatctccat ctaatacagc
    17581 tttcgtttgt gtgccgcctg catcagatcc agcgttcggc tcagttaatc cgaaagcacc
    17641 taatgtttta cctgacgcca ttggaactaa atatttctgt ttttgttctt ctgtaccgaa
    17701 ataataaatt ggagaagcac ctaatgaaat tgttgcagcg taacttaatc ctgtcccacc
    17761 acaagcacga ccaatttctt caactgctaa cgcgtacgat acagtatcgc cacctgaacc
    17821 tccatactct tcagggaatg ggatgcctaa taatcctagt tcgcccattt tttgaaatgt
    17881 ttcatatgga aattccccag ttttgtcata atacacagct ttcggtgcga tttccttttc
    17941 agcaaagtca cgtaccattt ctttaatcat ttgtttttcg cgagttagag taaattccat
    18001 tccgctacac accccttatc gaatattgag tttcgacagc gtgcgagttt ctactacaaa
    18061 cattacgaat taaaagacac gaatattagt tagacaattg ttataattct gtcataactt
    18121 aattttaaaa cagattctgt actaatgcac aaaaaaattc ctacattgtt ctacaacaat
    18181 atagggagtt ttgtgtcgaa ttatgtaatt tattgtttaa taatctctac cttttcccga
    18241 atcagaaatt tctactaaag cttcagggta tggttcaaaa tatgtttgtc ttaataaata
    18301 cttctcgtca aatcgaatgg cccatgattt taaaattgta agtaagctac taagcgggac
    18361 tttcttttct atatactttt gtatcaaatc taaaaaatga tctttttctt gttttttcaa
    18421 ctttgtttta aaatatccaa aaatatgctc acatacattt acattcgatg tatagcgggg
    18481 tgtgcgcata aataattcat ataatgtctt ctcatactta tcaaatacaa cttcaatcgt
    18541 ttcatttttt tgatttgcaa taatacgccc taattctttt tgtttcactt gattatatgc
    18601 cataaataaa tatttatagt ctgattgaaa cgatacgagt tcttttatgt ttttagtatg
    18661 tttaatcatt ttgtaatgtg caattgtaaa cagacgtgta aagaaatgtt ctctaataat
    18721 aaaattcgac aatctacctt cttcttcaat tggaagatgc gaaaattttt ttattactgc
    18781 tccgccaaat aagccagatc cctttccttt tgctggtgct ttttcaaaac cagaataaat
    18841 tttcacatca cgcgtaccac aacttggcga acggttcttt aaaataaaac catccacatc
    18901 aggtaaagtt tgtaaaaagc cgtttgaaaa ttgctccatt ttctccgtta catcttcccg
    18961 ggttgacggc tgcacaagct tattcacacc tttttcttct acaattcgta tcgtttcacg
    19021 aggagtcccc aatccaatct caacttctgg acaaacaggt ataaatgtaa caaatggctg
    19081 caaatttcgt attgttacat ctggaatcat ctcgccatta taacgacaag catcaaattc
    19141 taaacattta ctaacaacaa ttttcggttt tgcaaattgg cgcatcatat tacctccgtg
    19201 gcgttagtcc gtacaatata aattgaatcg tattttcaat ttccaattca tcattccatt
    19261 tttcttctgg taataataaa aaacgtgtta atagtaaccc taatacagct gataaagtaa
    19321 gtcgtaatac agaagatggg gggatttcaa taatctcccc ttcctcttga aactttacaa
    19381 ttaacttttt aaaatgtgaa agtaactctg tttctactaa atgttgtatt tcatttttca
    19441 attctggctg aaatggcact tcttgaatta atatttttat cattggaaaa tgcttttttg
    19501 caaattcaaa acgattatga ataacaactc ttagaagccc ttcatatgat tcatactccg
    19561 atttaaatat ttcctttgcg aaagcttgta cgaaaaatgg tgcagcaaac tttgttaatg
    19621 tcggcatgac gactgctaac aataaatctt ttttcgtttt atagtagcgg aagattgttc
    19681 cttccgctac accagcacgc tttgcaattt cacttgttga agtggcagca tatccttttt
    19741 ctccaaacat atcaacagct gcctctaata tacgcatttg acgttcattt cgtttatccg
    19801 tatttgtagc ggcaattaat tcttccagcc aatccttctt catctataat gcccctttgt
    19861 atcatcatta tatttttcga tgtttcttta atgcaaatac attccctatt gcaaataata
    19921 gagaaaaaag tagtaataca gttagatcta atgcaatctc tgtaaatcct tgatttcgaa
    19981 tcatcacttg tctcattgcg tcagcgccat atgtcagcgg aaataatttc cctaacattt
    20041 ggagccactt attcatagat tcaattggaa acaacccaga aaagaaaatt tgtggcacaa
    20101 tgacaagcgg tataaattga atcatttgaa attcattatt tgcgtatgcc gataaaaacg
    20161 tccccaaagt tagtgctgtt aaagaaagca tgcatgtaat aagtagcgtt agccatatgg
    20221 aaccagctac atacaaatct aaaatataaa ctgaaaaatt cacgataata attgattgta
    20281 taaatgcaaa gatcccaaac ccaataatat atcctacaac tatttcccac cttttaatgg
    20341 gagtcgataa taacctttct aaagtaccac ttaaacgttc tcttacgaaa gacacccctg
    20401 ataaaataaa tacaaagaaa aatgtaaaga aaccgattaa tacggggcct aacccatcaa
    20461 acattgtaaa atctttagtg ccatgtaagt aatttacttc aggcttcata acagatacat
    20521 cactcttttc tgtactcttt tgtaaaactt gaagtacagc acgatttttt gatgaatcac
    20581 ttccttctaa taaaagtttc attttcccat tctctaaata aattactgca tctacctttt
    20641 gctgttctaa ctcagaaatt gctttctctt tgccgtattc ataaattgag gcttcttgag
    20701 ttttcattgt ttttacaatg ggagcaggca catcaactac agcaatatgc ggtacatagt
    20761 ctttttgtgt aaacactagc gataataacc aaagtaataa cataggtgct ccgaacatca
    20821 tcgctaacga acgcttatct cgaaaaaatt ggcgaataat acgaatgatt acaccggtaa
    20881 ctctcatgat agggccacct cttccaacaa aaagacatct tcaatccttc ctgaggatac
    20941 ccgctttttc aattcttcag gtgttccagt cgctactagc tttccttctc taattaaccc
    21001 taggcgttca caatattcag cttcgtccat tatgtgtgtc gttacaatta tcgttgtgcc
    21061 tttctttttc aaattataaa atttttccca gatcgttttt ctaagaagcg gatctatccc
    21121 aactgttggc tcatctaaaa ttaatatttc cggttcatga aggagtgcta ttgcgagtga
    21181 taaacgcttc ttcattccac ctgaaaaatg ctgtacttgc tttttcatat gttgtgataa
    21241 ttgaacaagg gcaaaaacct cttcaattct ttctttttta tgctttccct ttaatccata
    21301 cattgttgcc atgaaatctg cattttcata tgctgataat tcttcgtata atgcatctgc
    21361 ctgagccata taaccaattc ttttcatttc atttaaatta ggcatgttcg tattgtaaac
    21421 aaacacttca ccttccgttg cctcattaat acctgcaatc aatttaataa gagtcgtttt
    21481 ccctgaacca gaaggcccaa ctaaaccaaa tatctctgct ttttcaactt gcaatgaaag
    21541 attgtgtaaa acttcttttt tccccaaact ttttgataca gtccgtaaaa taatggcagg
    21601 ttgttgcacg tattcttccc cctttttaaa aatgagtgag tactcacttt tattttactc
    21661 ttgcgtaatt atatgtcaaa cttcattgat tagtatgtat tgtcaatcaa caatacatac
    21721 taatcaatga aacagagtcg acattagaat ttcatttcct aaagtcgact ctgtttcatt
    21781 taaattttat attttacttt acgtttttaa attcatatat ttcctaattc tagcaacatc
    21841 taaagaatat tcgataacta attgctgtaa cggtaatata actgtgtcgg gatataaatg
    21901 ggcatattgt aatgtttctg catatttttc taaccttttt tctaaatact ttattatttg
    21961 atcaggatga cttactaata aacatttata ataataatgt atttgttcct caatcgccgt
    22021 atactcttca atttcatatt ctttatgcat gtgtacaccc ctttaagttt tttacatgaa
    22081 ttacttatca cgcttttcac tcgactaatt tttaagtttt ttgattattt acactataac
    22141 aaactcttcg ggtcaaattt tgttacttta tgtaacgtag aaaattttta acaaaattgt
    22201 aatgttaact tgtataaaat gcattaggcc tatttttctc tgtacaaaaa agtcgtacag
    22261 ttcaatttaa ctgtacgact acaagttctg gcctattaaa aatcctttgc ggaatgatac
    22321 tattacctaa tcctctactt actaccatag acgtattttt tttcatataa accggctgta
    22381 tatgtaggga atatcccttg attcggggca actaaccctc cgataaatgg caatctaact
    22441 tgccctccat gagcatgccc cgataacact aaatctattt gctcatcagc atactttgcc
    22501 agaaactcag gcctatggga tagtaataca ttatatgtat ccgcctgtat ttcaattttc
    22561 gcttttataa tttcatcttt gacaatattt ccttcatcac ggtttccagt aacaaattcc
    22621 ggatcatcaa taccaagtaa atttattttt tgttcctctt tttgaatcgt tacatgttca
    22681 tttcttaaaa cagtaacatg atgtttcttt aattctttct ctaaatcatt atatttttct
    22741 gaccattttt catggtttcc tgtcacaaaa tagacgggat actcctttac aagctctcgt
    22801 attaattcca tactaacttc tgcatcgtat gatttactgt caattagatc acccgtaatt
    22861 gcaataatat ctggatttat gctttttact ttttgaatta aagtttcttg attgtcgcca
    22921 aattttttat tatgtaaatc tgaaatttgt agaattttaa aacctttaaa agaagagggg
    22981 attttattag atgttatatt aacttcagtt atacttatta aattgttttg tgaatataaa
    23041 aagatactaa aacttactaa aatactaata agtaatatga ttcttttagt ctttttgttc
    23101 atatttcctc ctaaaatctt gatcagtact acagttcaca ataaatatta cgtgcccttc
    23161 gcattcagaa taactgaaat tttttaattg atttgtagta tttgttatag ttttatacga
    23221 cactaataaa atttttcaat ctcattcgta ttagctcatt cgctataaag tggagctttg
    23281 atatcctagt tgtcatgcat gagtgtatga tgtcatgctc atttttcagt gaatttatag
    23341 cgaatcactg gaagctcttc atcatattat tatttatctt acttagtttg ataacgatat
    23401 aacgataatt cctatagttt tttataaaaa aattgtgtac ttttctcaaa ttatatacga
    23461 cattcgcttg taaatatatt attaccactc cgattttaat ttgtttaaaa cgtgcataga
    23521 gagaattgaa acactaaatt accttatgaa aagttattat tgtaccattt gttagaaaat
    23581 tgaaaaaaca tgtgtagata gatatcattg taaatgaata tataattaat tttgattttc
    23641 tgacataatt cttaacctag tttttgcgtg cattatgaaa taaaatattg ccccatgtca
    23701 gtctttaaaa aattatatat cattacttta agggaggaag aaaactatga agatgaaaag
    23761 aaaaatcatg atgacgacag cacttgcagc tacattagct acaggtgcac taccgactac
    23821 atcggtgttt gctgcagaaa aagaggctcc tatccaacaa aaagaggcac aaatgagtat
    23881 tcaaccattc gcacaaaata atttggaaac agcggttaag gctgccttaa atggtccaga
    23941 agttaaaaaa attaaagtat ttgagcatga atttaatgta aaaccaattg aagtagtaaa
    24001 tttaggtggc ggtaaaacat atgttaaggg acaaatttct catcatttaa gttttcgtcc
    24061 agatgatcaa ttttattatg agtttacagt gcaagatgga aaggtaatag ataagcctgt
    24121 atttaatatt gatagaggtg gttggacacc atttgctgct ccacttttat caattcttgc
    24181 tgcttataat gggatcccag ttaatccaaa tgatttaaat gcacttggtc agcagattgg
    24241 gaaagttata gatggcagct gggaacatgc agcccaatct atcgcaactg tagttagttt
    24301 aagttttaat gaatagaatt ttttaatttt tattagtatt gtagagatcc acttttccta
    24361 agtagccttg ttataagaaa ttctgaaaca gctattaata gatttttacc actcagtcac
    24421 gttatcttga tttgttaacc agcttatcat tcattatatg tcacaaaata gaagtctttt
    24481 ttaaggcttc tgttttgttt gtatacaata cgataaaagg ttgttttttc gagtccatac
    24541 ttcgattctt taagaatccg tttggctatt aggtacaatt cattacaaca aattattaaa
    24601 gtctaaaata acttacacct cctatttttt aatttttttc aaatacaaca attcattatt
    24661 taaagagtgg caacaataaa tatagtaaaa aatcatctta ttttaactat tgtttaaaag
    24721 tcaggagaga taaaatgaac aaaatgaaaa acttctttaa aattagcatc ctcacttgtt
    24781 ttacactagt aagtttaagt acaccatcta ctatttttgc tgatagtcat cccggttatt
    24841 cctatgaatc caatataggc tatcaaaatc cagcttggat gtcgaaagta gcagattcaa
    24901 taaaattaag tgaattatct attccaggga ctcacggtac aatggcttta catggcgcaa
    24961 gttttcttga tgaaaatttg acaagaaatc aaactatgag tctaccccaa caattaaatt
    25021 ctggaattcg atatgtagat atgcgtgtta aacgtgtaaa agattctttt gcaatgtacc
    25081 atggtattgc aaatcaaaaa gcagtgtttg aagatgtatt aaaagaggca attcaatttt
    25141 taaaagatta tccgacagaa acaattttaa tgcgcttaaa agaagaaact actcctgaaa
    25201 gtggatcact atcatttgag gagatatttt taaaatat
//
