LOCUS       NZ_WBPF01000002        23192 bp    DNA     linear   CON 16-NOV-2023
DEFINITION  Bacillus sp. CH140a_4T NODE_2_length_91155_cov_43.365837, whole
            genome shotgun sequence.
ACCESSION   NZ_WBPF01000002
VERSION     NZ_WBPF01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Bacillus sp. CH140a_4T
  ORGANISM  Bacillus sp. CH140a_4T
            Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus.
REFERENCE   1  (bases 1 to 91253)
  AUTHORS   Olmedo-Alvarez,G., Saldana,S. and Barcelo,D.
  TITLE     Bacillus from the desert of Cuatro Cinegas, Coahuila
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 91253)
  AUTHORS   Olmedo-Alvarez,G., Saldana,S. and Barcelo,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (01-OCT-2019) Ingenieria Genetica, Cinvestav, Libramiento
            Norte Carretera Irapuato Leon Kilometro 9.6, Carr Panamericana
            Irapuato Leon, Irapuato 36824, Mexico
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2013
            Assembly Method                   :: A5-miseq v. 2013
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 11/16/2023 02:51:40
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 5,653
            CDSs (total)                      :: 5,545
            Genes (coding)                    :: 5,358
            CDSs (with protein)               :: 5,358
            Genes (RNA)                       :: 108
            rRNAs                             :: 8, 3, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 4, 1 (5S, 23S)
            partial rRNAs                     :: 4, 3, 1 (5S, 16S, 23S)
            tRNAs                             :: 90
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 187
            CDSs (without protein)            :: 187
            Pseudo Genes (ambiguous residues) :: 0 of 187
            Pseudo Genes (frameshifted)       :: 78 of 187
            Pseudo Genes (incomplete)         :: 114 of 187
            Pseudo Genes (internal stop)      :: 56 of 187
            Pseudo Genes (multiple problems)  :: 47 of 187
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 10:06:47
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 24979
            Orig. end                         :: 48171
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            WBPF01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..23192
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..23192
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..23192
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:13192](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..13192
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    235..250
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.55"
                     /tool="antismash"
     gene            272..670
                     /locus_tag="F8162_RS00135"
                     /old_locus_tag="F8162_00135"
     CDS             272..670
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006917351.1"
                     /locus_tag="F8162_RS00135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00135"
                     /product="hypothetical protein"
                     /protein_id="WP_000683504.1"
                     /transl_table=11
                     /translation="MKHWGLTCMKMVNISIFLCIGCLGWMNIIILFIQREWATDLLGWI
                     GLGLLIWYTLILLTLQIIHSELRCRIDDRAKLAFFIWFVGIGHFGLLQFIQDQQSTVLT
                     LLFHVFAIIPILLALIYGLIVRKYFNQS"
     gene            698..1825
                     /locus_tag="F8162_RS00140"
                     /old_locus_tag="F8162_00140"
     CDS             698..1825
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001247229.1"
                     /locus_tag="F8162_RS00140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00140"
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="WP_098944551.1"
                     /transl_table=11
                     /translation="MRPEIKEVVDKTIQEDIAQEQKKKKKKKSWLLTLLFGSSTFTIGL
                     FVCIGFILFIVLAQGIGKKEEEAPATIPSNGMTVCRPGGKTVAPEELQPHLGGVFTGKA
                     QAFLNAGTQNQIDPVLLAAIARLETGNGTSNAVKNYNNPGGLMDPGSSQMKGFMKFATL
                     DEGINAMARNLYKNYIGMGITTIEAIGAKYAPPGAANDPHGTNGLWPVLVTKFVAQMGG
                     LTFNCEAGKPGGVVDTGSASSQGFIRPIAQTTITSPFGPRWGTIHKGIDYSCQDGVTAI
                     AASKGGVVELAEFGAGGSGFGGYGNVVVINHGNGYWSLYGHMSSITVQKGQNIGVGQQV
                     GVCGRTGQVTGPHLHFEIKTAFKFGQVDPAPYLPK"
     gene            1850..2434
                     /locus_tag="F8162_RS00145"
                     /old_locus_tag="F8162_00145"
     CDS             1850..2434
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000808979.1"
                     /locus_tag="F8162_RS00145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00145"
                     /product="hypothetical protein"
                     /protein_id="WP_151582463.1"
                     /transl_table=11
                     /translation="MKQGIVGLVILVLVGISVWLWNQNRTLQHKVEQTEKKWTEQVKEL
                     KTENRALEKRVTVLTENTQDKGQEVAKQFVELLIQNDNKQKEKPGFEKIKEMITGEARN
                     KLLNAPEDAHNHIEDDGSMHIQTKAKITDMYYIKTADNKADVTVKYDYLVTVDGTEQQE
                     KHTMKLNLLLEGEKWFVENYEFQINTGIEGP"
     gene            2456..2773
                     /locus_tag="F8162_RS00150"
                     /old_locus_tag="F8162_00150"
     CDS             2456..2773
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075391.1"
                     /locus_tag="F8162_RS00150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00150"
                     /product="hypothetical protein"
                     /protein_id="WP_074569885.1"
                     /transl_table=11
                     /translation="MNQNVLHHIGYEILQETFVLIRNVFSYSNQDESSVTYVREIADAL
                     HNIPHSIQKQHDKFLEFEFKLLEETLMQMDFGKVAAQNIPYFKMYAVRVQQLLQKRYKE
                     V"
     gene            2799..3095
                     /locus_tag="F8162_RS00155"
                     /old_locus_tag="F8162_00155"
     CDS             2799..3095
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006917359.1"
                     /locus_tag="F8162_RS00155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00155"
                     /product="hypothetical protein"
                     /protein_id="WP_098522364.1"
                     /transl_table=11
                     /translation="MIVLGIGLSVLLIAFLFIQVYPFQEQKLEQRKYDEYGIWIIICTG
                     VCLYVSHHFLQENTWQWGLKIIGATFFTGFSIGCVGKQSIYDFQHKRFPFQKK"
     gene            3223..3540
                     /locus_tag="F8162_RS00160"
                     /old_locus_tag="F8162_00160"
     CDS             3223..3540
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016123838.1"
                     /locus_tag="F8162_RS00160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00160"
                     /product="hypothetical protein"
                     /protein_id="WP_098903063.1"
                     /transl_table=11
                     /translation="MLFLKVIAYILLSIGVCTVVLAGIAAIVKKQMIIANINLLLAMYY
                     FCSGSLLYLCTLWETQDIFLQAFLILIVGITIIRLRKSWYVPQIRTLQKLQEEATNKND
                     L"
     gene            3572..3784
                     /locus_tag="F8162_RS00165"
                     /old_locus_tag="F8162_00165"
     CDS             3572..3784
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016083788.1"
                     /locus_tag="F8162_RS00165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00165"
                     /product="hypothetical protein"
                     /protein_id="WP_151582465.1"
                     /transl_table=11
                     /translation="MIHQYELNFSVMYSGKVTGSQSTIIPASSLEEANEKLQSEVKRRL
                     GKCSIKVNTASLCVSEDSRYVIEQK"
     CDS             4025..4159
                     /gene="allorf_29004_29138"
                     /locus_tag="allorf_29004_29138"
                     /protein_id="allorf_29004_29138"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MLKGMWLLLCESWRVILKNSAQSPFVWIRNEAKWCFESLDWIEI"
     CDS_motif       4025..4093
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MLKGMWLLLCESWRVILKNSAQS"
                     /locus_tag="allorf_29004_29138_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       4094..4159
                     /prepeptide="core"
                     /locus_tag="allorf_29004_29138_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-7.00"
                     /molecular_weight="2664.0"
                     /monoisotopic_mass="2662.3"
                     /core_sequence="PFVWIRNEAKWCFESLDWIEI"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MLKGMWLLLCESWRVILKNSAQS"
                     /leader_location="[4024:4093](+)"
     gene            4356..5282
                     /locus_tag="F8162_RS00170"
                     /old_locus_tag="F8162_00170"
     CDS             4356..5282
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014990400.1"
                     /locus_tag="F8162_RS00170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00170"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="WP_225990119.1"
                     /transl_table=11
                     /translation="MYNERKTSYEMGRGKPMSNQQLVNLRIDFAFKQLFGTSGNEDILI
                     AFLNALLQDSLESPIVSLQLEDPHLHREHEEDKLSILDISATLDTGTKVNIEIQLNNNH
                     DMIKRSLYYWGRLYTSQLQKGMPYSSLHKTITINLLNFVMFSEYEAFHTTGVLWNQQQQ
                     KVLSSDIEVHIVEIPKLMQQWRNEQVNPWEDSFVRWLLLLPANEDEQLTQTLEDIAMNQ
                     DPILQKAMNKWERMSQDSSFRQAYEAREKALMDEAAKFAHARNEGIQEGKIQMIKGMHE
                     LGVPIETIAKASKLSIEEVQHILSRNS"
     gene            <5346..5693
                     /locus_tag="F8162_RS00175"
                     /old_locus_tag="F8162_00175"
                     /pseudo=""
     CDS             <5346..5693
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002026764.1"
                     /locus_tag="F8162_RS00175"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="F8162_00175"
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="FILWLLLLSGIEDE"
     gene            complement(5952..6794)
                     /locus_tag="F8162_RS00180"
                     /old_locus_tag="F8162_00180"
     CDS             complement(5952..6794)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262590.1"
                     /locus_tag="F8162_RS00180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00180"
                     /product="hypothetical protein"
                     /protein_id="WP_151582471.1"
                     /transl_table=11
                     /translation="MANDIFKHARKRGHSVVENALLDDCNLTGMAKYLLIQFCSHRNGY
                     WKVTMPDIIKRSKNGRDAHYSALKELIHNKYVARVKVLEKGKYKEQIYIYGQIKEDVAE
                     MLNETIQEQMFKGYVVEVAFGNPLTENPNVENPNSDFQYNIKYQRKNTKKENTNIFIND
                     IAKFDDDKRSFSSLTEEQINLIVNTLREATKDDLTDRSFTAVLKKVMDKYNQGKISNFR
                     DYLITALVNKIEELEIRRIKENAKKQLQEDKLDRSIITRTLSEHEYTGKVPFYDWIAS"
     gene            complement(7305..8699)
                     /locus_tag="F8162_RS00185"
                     /old_locus_tag="F8162_00185"
     CDS             complement(7305..8699)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.3"
                     /locus_tag="F8162_RS00185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00185"
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_151582473.1"
                     /transl_table=11
                     /translation="MKLKITLLYGASIISLIFILFIVQFIIATYFVFSQGSNNYKQSTP
                     ENIALEFGKYLNLDNQDISITNEGKNILNANNAWLQIIDSNGNVVRDMYAPNKSKQHYN
                     AKDIAMLYKYAVDGYTYFISEVEIEDKKWSYLIAFPSNKVSRYMIYLNLDNVLSFYPYG
                     ILISIGSALLCLLIFSYFIARYFAKPVLVLIHNITNLFNGLYTQKDVNKGLFKDVFTIL
                     NKLAIKLKNVENDRSRLEIMRQEWITNLTHDLKTPLSSIKGYSELLTDDQYNFTIEERK
                     EYVAVIKKKALYIEQLIGDLRLTYQLKNATIPLEKKDKDIVGIVRELVITCLNNPSYKR
                     KTFDFSTNQQNIILKVDEILLTRAINNIMMNSIVHTPEGTHITVKICNTKKTTKIIIED
                     NGPGIPKKELEQVFERYFRGSNTKNIEGSGLGLAIAKQIIISHDGYIDIKSEEGKGTCF
                     IITFKH"
     gene            complement(8696..9433)
                     /locus_tag="F8162_RS00190"
                     /old_locus_tag="F8162_00190"
     CDS             complement(8696..9433)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000581656.1"
                     /locus_tag="F8162_RS00190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00190"
                     /product="response regulator transcription factor"
                     /protein_id="WP_151582475.1"
                     /transl_table=11
                     /translation="MFIDPKYLKSKKILLIDDEEEILKILEIVLRKEGFYHIDKASLGK
                     KGIQMCREVDYDLIILDIMLPDIDGFSVCQQLRNITLAPIFFLSAKEEDSDRLIGLSLG
                     GDDYITKPFSPKEVAFKMKAFFRREQYHHQEEKNTDKGLYNFGDVVLNEKKGTVLKNNI
                     PISLTAKEFYLLLYLIKNPNQVFSLPQLYKSVWNEECTGCENVIMVHIRHLREKLEDNP
                     SNPKYILNVRGLGYKMSIEGNVE"
     gene            9740..9898
                     /locus_tag="F8162_RS00195"
                     /old_locus_tag="F8162_00195"
     CDS             9740..9898
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) L_biotic_A"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mature_d"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002175376.1"
                     /locus_tag="F8162_RS00195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00195"
                     /product="lacticin 481 family lantibiotic"
                     /protein_id="WP_063263939.1"
                     /sec_met_domain="L_biotic_A (E-value: 1.1e-23, bitscore:
                     75.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="mature_d (E-value: 1.1e-14, bitscore:
                     46.3, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKNFELKALEAINDLTDAELENVVGADKGQFDTISHECHWNTWQ
                     FLFTCCS"
     CDS_motif       9740..9820
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEKNFELKALEAINDLTDAELENVVGA"
                     /locus_tag="F8162_RS00195_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9821..9898
                     /prepeptide="core"
                     /locus_tag="F8162_RS00195_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="4.50"
                     /molecular_weight="2944.2"
                     /monoisotopic_mass="2942.3"
                     /core_sequence="DKGQFDTISHECHWNTWQFLFTCCS"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEKNFELKALEAINDLTDAELENVVGA"
                     /leader_location="[9739:9820](+)"
                     /alternative_weights="2962.2"
                     /alternative_weights="2980.3"
     gene            10001..13192
                     /locus_tag="F8162_RS00200"
                     /old_locus_tag="F8162_00200"
     CDS             10001..13192
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="F8162_RS00200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00200"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_151582477.1"
                     /sec_met_domain="DUF4135 (E-value: 1.2e-111, bitscore:
                     366.1, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.8e-75, bitscore:
                     246.5, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTSTDSLNNINELLDNSTWAHALYLNERENIEINNSINEDSVTE
                     WLQKFNNNKELLLERLDQEKITYSQFTSILSSPQVDHTYKKMEWFLTIKEIFLQTKDEH
                     NDGEFDKLFSKDVPFISFIIPFVNYVKEKIFKEIDQTNTLHIFEKKCIEETIVKLVSST
                     IFKYSLKTLIYELNKARIQNELSGDTPEERYNYFEKEKIGKSSQILAVLSQYPVLARLI
                     SEAISNIINNLIRFINQFTNDYREIETTFEISITKVINIQALGDSHNKGQHVLKLDFND
                     NQSIIYKPRSLSIDIHFQQFLNWINEKNEIHNFKTIKVINKGTYGWQEFVTYKDCTTEE
                     EVRRFYERQGQYLCVLHFLNATDFHYENLIAHGEHPMLIDLESLFHTTIKNNQSLKSPA
                     NRKAINILNDSIARTGLLPIFVDNDLFDIDVSGIGGGKKQQVERYKIDKVKTDEMRLIK
                     GSIYLEAGLNSPKINGEVCEAFNYTQSIKEGFYKTYKLLENYKEALLSTDSPIHAFSKD
                     RVRIILRSTIVYSHLLDASTHPKYLKSGIDRVKLFDYMWLLVDYIYNRKNAAICECKDL
                     LAGDVPYFYVDVDSTKILTHQNFEIKDMFAKDSFNMVLEKIKNMGEEDCNRQLDFIEKS
                     LLTKYYLDINNMNKAIEDFNKKSSYEGTLLNKEAFLTEAIRIANVLEKEAIWAEDFSDV
                     TWIGIGMSSDEKLNYKAMDMGIYDGILGMAIFFAYVGKESGIPKFKKIAKACLQTALNE
                     KNATKKAYISAFSGYSSAVYVLTHFYKLWGEKELLDEAINFINEIEPHIDKDTTFDLLN
                     GSAGTLLVLLNFYKVTGFQKALDIAIKCGDHLLKNAVKVNGGTAWTISPKHTPLTGLSH
                     GTSGIALALIRLTEETGDQNYLNAALQALNYENSTFSSKENNWLDLRQNMNRDTPKSVI
                     HWCNGTVGIGMARLKILEHYQSEIFVRDLEKSIEITMERGFLNPNYSLCHGDLGNLDLL
                     LLAATRIDKYKPLSKFVYEKASSMLQYVQEDNQNWKCGIPGGQQTPNFMVGLSGIGYQL
                     LRLYNSELPSVLTLE"
     gene            13294..15471
                     /locus_tag="F8162_RS00205"
                     /old_locus_tag="F8162_00205"
     CDS             13294..15471
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.3"
                     /locus_tag="F8162_RS00205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00205"
                     /product="peptidase domain-containing ABC transporter"
                     /protein_id="WP_151582479.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.8e-39, bitscore:
                     127.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKWNIRNKKSKVPIVEQMSQYECGICCLNMILKYYNYEIKLSELR
                     PYFEESRNGTTLLKIKQVAEKFNMHCIGKKVSIDFLLEYQDLPLPFMVFFENKHYVVLE
                     KVTGTHFFIADPAIGHVKMTKKEFEEKYSGTIFIMIPNEDFVPKKQKQKSSIKKIIVEN
                     KKPLLYLVLFSLLIQLISVGVPIIMKTSIDLIVMQKKYAMISTFIISFLILCIFQVGFN
                     LFKDFILIKLQNSLDYKLTNKFVSHLLKLPYKFFENRSRGDLILRANSNVRIREFLSQN
                     LIMSLINICLVFVLFTYMFIESRLLALVVLLIGIIQVLTIVFTKNKLKYLTKSQITSQT
                     RYSSFMTEMLGGMSTIKSLGIENNIYKNWEELLSKQVEANKNKSYFQLKVDTITKSLFF
                     VAPLIVICIGIYQVVNGQITIGTLFAFQSVTISFLTPLNSIAMLLNDIVTTETLLDRID
                     DVLTEEKEPTPDNDVFIKLKGDIKLDDVSFRYSKFGNYNLKNISLNIASGQKVAIVGKS
                     GSGKSTLAALLSGLYTPTHGNIYFDDTNHSTLSKETLRGNIGVVLQENFLFNKTILENL
                     TIHNNDINMDEILFATNLAQIHEDIQVMPMGYHTVISEGGSNISGGQRQRLSLARALIS
                     KPSILILDEATSALDTITEKKLNEGIQNLNCTRVVIAHRISTIIDSDIIVVMDQGEILD
                     SGTHEQLLLRCNYYKDFYYSNFHDSKQLQKM"
     gene            complement(15627..16370)
                     /locus_tag="F8162_RS00210"
                     /old_locus_tag="F8162_00210"
     CDS             complement(15627..16370)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000927298.1"
                     /locus_tag="F8162_RS00210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00210"
                     /product="ABC transporter permease"
                     /protein_id="WP_098624276.1"
                     /transl_table=11
                     /translation="MLRLAISTELLKLKRSKMWIIMLCIPFICILLGLLNFQFNREVLA
                     GAGKNEWMQAWTQIGMLYSMFLFPILIGVYSSLVCRYEDSGNNWNKILSLPISITNIYL
                     SKLIVISLLSLVTQIFLVILYIISGNFLDFSHPFPMVLLKWVFYAWIGTISIASLQLWL
                     STSLKSFVVPIGIGVAFTFLGIIFYLMGIGYIWPFSYSALAMDPIKLHGIQGFKNTFFF
                     FIMNIFYTTVFLFIGIRRMTRKDIK"
     gene            complement(16386..17126)
                     /locus_tag="F8162_RS00215"
                     /old_locus_tag="F8162_00215"
     CDS             complement(16386..17126)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002175372.1"
                     /locus_tag="F8162_RS00215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00215"
                     /product="ABC transporter permease"
                     /protein_id="WP_098624277.1"
                     /transl_table=11
                     /translation="MISLLRSEFLKLKRKRFIFVIILMSILEIAWVFALTAKARQEFHI
                     WDNLISNFGILNGLFVPIMIATIVSRLVDVEHKENTWKMLLATPINKASLYICKIITTM
                     ILLLIPLIILFFSMLIIGNVLDYPGSFPVNLILKFLATTWISSIAIVALQTWVSVLIKN
                     QAFSLTVGILGSFLGYLGQMIPISKFLIWTYPSITGPLMLKVVGNQMTYQPNVNSLSNL
                     FLSIVVGIILILVGLKHFMKKDTN"
     gene            complement(17126..18040)
                     /locus_tag="F8162_RS00220"
                     /old_locus_tag="F8162_00220"
     CDS             complement(17126..18040)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016104007.1"
                     /locus_tag="F8162_RS00220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00220"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151582481.1"
                     /transl_table=11
                     /translation="MSKYIVQTHNLSKKHGDTFNVNNIDLKVNEGEIYGFLGPNGAGKT
                     TTIKMLLGLVKPTNGDIKIFGQDLKTNRLNILKQIGSLVESPSYYGHLTGYENLEIIRR
                     MLNVPRKNIDEVLEIVRLKNQKEKLVKNYSLGMKQRLGIASSLLAFPKLLILDEPTNGL
                     DPSGIHEIRELIKELPSKYGMTVIISSHLLSEIDHIATQVGIIQNGVLIFQDDIAKLRQ
                     QSNSIIRMKVDNLSDAHKILLRNEIFSKIEGDSLVLNTYTEEQVAQANRLMINNNMSVY
                     RIEEEKRTLEDIFLELTAKGGSL"
     misc_feature    18117..18135
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 22.95"
                     /tool="antismash"
     gene            complement(18532..18894)
                     /gene="crcB"
                     /locus_tag="F8162_RS00225"
                     /old_locus_tag="F8162_00225"
     CDS             complement(18532..18894)
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012096104.1"
                     /locus_tag="F8162_RS00225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00225"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_151582483.1"
                     /transl_table=11
                     /translation="MTEYHALLVAIGGFFGAISRFGISNWFKKRNLSSFPIATFLINLT
                     GAFLLGYILGKGIDKSWQLLLGTGFMGAFTTFSTFKLESIQLGANKRWGIFFLYIGASY
                     IIGILLAFLGIQVGKI"
     gene            complement(18894..19319)
                     /gene="crcB"
                     /locus_tag="F8162_RS00230"
                     /old_locus_tag="F8162_00230"
     CDS             complement(18894..19319)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:1903425 - fluoride transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:1903424 - fluoride transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crcB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000323413.1"
                     /locus_tag="F8162_RS00230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00230"
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="WP_151582485.1"
                     /transl_table=11
                     /translation="MVYIIVGIAGVLGALSRYYLGLNIDTFWHHSFPLATLLINLIGCF
                     VLSWITTYISRLNIFPSEIVTGIGTGFVGSFTTFSTFSVETVKLINHAEWIFAILYVCF
                     SMLGGLLMSGIGYKLGITLFVKRTQKKSVLQSKGGIK"
     regulatory      complement(19379..19438)
                     /bound_moiety="fluoride"
                     /db_xref="RFAM:RF01734"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF01734"
                     /inference="COORDINATES: profile:INFERNAL:1.1.4"
                     /note="Fluoride riboswitches increase expression of
                     downstream genes that help mitigate the toxic effects of
                     very high levels of fluoride; They are found in a wide
                     variety of bacteria and archaea; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     gene            complement(19557..19943)
                     /locus_tag="F8162_RS00235"
                     /old_locus_tag="F8162_00235"
     CDS             complement(19557..19943)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016098102.1"
                     /locus_tag="F8162_RS00235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00235"
                     /product="DUF202 domain-containing protein"
                     /protein_id="WP_150159224.1"
                     /transl_table=11
                     /translation="MRQQKTTEKAFETVDSKYIQQHLANERTYLAWLRTAIAIAGLGFL
                     VANLHLAVRKELSTFNNKVAIGIGIGSVIAGIGIIIIATLQYLIKRQNINSQTFRAHTT
                     LIIWLSTLVIAVILVISSYFLLII"
     gene            complement(19961..20773)
                     /gene="lgt"
                     /locus_tag="F8162_RS00240"
                     /old_locus_tag="F8162_00240"
     CDS             complement(19961..20773)
                     /EC_number="2.5.1.145"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008961 -
                     phosphatidylglycerol-prolipoprotein diacylglyceryl
                     transferase activity [Evidence IEA]"
                     /GO_process="GO:0009249 - protein lipoylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lgt"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016098101.1"
                     /locus_tag="F8162_RS00240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00240"
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="WP_150159222.1"
                     /transl_table=11
                     /translation="MTEQTHPLDPIAIHLGPIAVHWYGVIIGIGAILGFILATHEGKKR
                     GVPSDIFYDLIFLALPISIVSARIYYVFFEWNYYKDNLGEIFAIWHGGIAIHGGIIGAV
                     LTTIWFTKKRNLSFWKMADILAPCLLLGQAIGRWGNFINQEAHGGIVSKSFLESLHLPE
                     FIINQMNINGTYYHPTFLYESIWNITGVALLLLLRRANLKRGEIFLTYLLWYSVGRFFV
                     EGLRTDSLMLTSHIRIAQLVSIGCIICSILIAWYRRKKGYAHLHYTAD"
     gene            21206..21367
                     /locus_tag="F8162_RS28520"
     CDS             21206..21367
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002203071.1"
                     /locus_tag="F8162_RS28520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_190322698.1"
                     /transl_table=11
                     /translation="MNIIDLELVRKRKIKGNKMITIPIIERVFKVNEEIQFEVTGEKEL
                     PIAWLEKE"
     gene            complement(21620..22267)
                     /locus_tag="F8162_RS00245"
                     /old_locus_tag="F8162_00245"
     CDS             complement(21620..22267)
                     /GO_function="GO:0000150 - DNA strand exchange activity
                     [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006310 - DNA recombination [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017674596.1"
                     /locus_tag="F8162_RS00245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F8162_00245"
                     /product="recombinase family protein"
                     /protein_id="WP_151582487.1"
                     /transl_table=11
                     /translation="MSNVYGYIRVSTKDQNEQRQLHKMMERGVEARRIFVDKASGRHFD
                     RPQYQLLRKILSTGDIVYIDALDRMGRNYDEVISEWKYITRQLQADIVVLENETLFDSR
                     KFREMGDMGRLMEDQFLSLLSYVADQERKKIRQRQAEGIAVAKSQGKHLGRPQFNLSSL
                     SQKQLYIIEETYPKWKDKKITGVQFMEMLDLKKNTFYKIIKEYERTLNQNQL"
ORIGIN
        1 ttatcccaac ggaacctatt tcttctgatt tgacaccagt aaatgagaaa gaagtaagca
       61 aaaatgagcc aattcaagaa aaagcagaaa caatcgatac gccagatata caatatggag
      121 ctgtagccgc gggaagtgaa aactggatgc cttctactga tccgcaaaac ttagataatt
      181 tagatgattt ggagccacaa aaaaaagatg agtagagtcc tagtctttta ggactttact
      241 atttttttac gcaaaaagga gcgatttatc tatgaaacac tggggattaa cttgtatgaa
      301 aatggtgaat atcagtattt ttctttgcat tgggtgttta ggatggatga acataattat
      361 tcttttcata caaagagaat gggcgacaga tttattagga tggattggtt taggattact
      421 tatctggtat acactcattc ttctcactct tcaaattatc catagtgagt tacgttgtcg
      481 tatagatgat agagcgaaac tagccttttt catttggttt gtaggaatcg gtcattttgg
      541 attactacaa tttatacaag accagcaatc tactgtttta acgctactat ttcatgtttt
      601 tgcgattata cccattcttt tggcccttat atatgggctg attgttcgaa agtatttcaa
      661 tcaatcttga tacatgttgc aaagggggag ggatgatatg agaccagaaa taaaagaagt
      721 cgtagacaaa acgatacaag aagatattgc acaagaacaa aaaaagaaga agaaaaagaa
      781 atcctggtta ctgacacttc tttttggaag ttctactttc acaataggat tgttcgtctg
      841 tattggattt attttattta tcgttttggc gcaaggcatt ggcaaaaaag aagaggaagc
      901 gccagcaacc atcccaagta atggaatgac ggtttgtcgt ccaggtggaa aaacagtggc
      961 accagaagaa ctacaacccc acctgggcgg cgtttttacg gggaaagcac aagccttttt
     1021 aaatgcagga acacaaaatc aaatcgatcc cgttttacta gcggccattg caagattgga
     1081 aacggggaac ggtacttcta acgcagtaaa gaattataac aaccctggtg gcctcatgga
     1141 ccctggtagt tcacaaatga aaggtttcat gaaatttgcc accttagatg aaggaatcaa
     1201 cgctatggcc cgaaacttat ataaaaacta tatcggtatg gggattacaa ctatagaagc
     1261 aattggagcg aaatatgcac cgccaggagc cgcaaatgat ccgcatggta caaatggttt
     1321 atggcctgta ttagtaacaa agtttgtggc gcaaatgggc ggccttactt ttaattgtga
     1381 agcgggaaag ccaggcggcg ttgtagatac gggatcagca agttcacaag gatttattcg
     1441 tcctatcgct caaacgacga ttacaagccc atttggacca cgctggggca caattcataa
     1501 aggtatcgat tattcttgcc aggacggtgt caccgcaatt gccgcgtcga aaggtggcgt
     1561 tgtagagttg gcggaatttg gcgcaggcgg aagtggcttc ggcgggtacg gaaacgtagt
     1621 tgtaatcaat catggaaatg gatattggag tctatacggt catatgtcat ccattaccgt
     1681 acagaaaggg caaaacattg gagttggtca acaagtaggc gtttgcggaa gaacagggca
     1741 agtaacaggg ccacatttgc attttgaaat taaaacagcc tttaaatttg ggcaagtcga
     1801 ccccgcacca tatttgccga aataagcgga aaaaaaggga ggattaggga tgaaacaggg
     1861 aatcgttggt ttagtcatac ttgtactggt aggtatcagt gtatggctat ggaatcaaaa
     1921 tcgcacttta cagcataaag tcgagcaaac ggaaaagaaa tggacggaac aagtaaaaga
     1981 gctaaaaaca gagaatcgag cattggaaaa gcgcgtaaca gttttaacag aaaacacgca
     2041 agataaaggg caagaagtag caaaacagtt cgtagagttg ttaatacaga atgataacaa
     2101 gcaaaaagaa aagccaggat ttgaaaagat caaagaaatg ataacgggcg aagcaagaaa
     2161 caaattatta aatgcgccag aggatgcaca taaccatata gaagatgatg gctctatgca
     2221 cattcaaacg aaagcaaaga taacagatat gtactacatc aaaactgctg ataataaagc
     2281 ggatgtaacg gttaaatatg attatcttgt aacggttgat ggaacagaac aacaagaaaa
     2341 acacaccatg aaattaaatt tactattaga aggtgagaaa tggtttgtag aaaattatga
     2401 gttccaaatc aatacaggaa ttgaaggacc atagggaaag gaatgagggg agttggtgaa
     2461 tcaaaatgtg ttgcatcata tcgggtatga aatattgcaa gaaacgtttg tattgattcg
     2521 aaatgtattt tcctattcaa accaagatga atccagtgtg acatatgtgc gagaaattgc
     2581 ggatgccttg cataatattc cgcattccat tcagaaacaa catgataaat tcctagaatt
     2641 tgagttcaaa ctgttagaag aaacattaat gcaaatggac tttggaaagg ttgccgcgca
     2701 aaacattccc tattttaaaa tgtatgcggt acgtgtacag caattgttac agaagcgcta
     2761 taaagaggtg taatcgagtg gaaatggggc gataaaaaat gatcgtattg ggaattgggc
     2821 tgtcagtttt gctgatagcc tttttattta tccaggtata tccgttccag gaacaaaagt
     2881 tagaacagag aaaatatgat gaatatggaa tctggatcat tatttgtaca ggggtatgtc
     2941 tctatgtttc gcatcatttt ttacaggaaa acacatggca atggggatta aaaatcatag
     3001 gtgcaacttt ttttacaggg ttttcaattg gatgtgttgg aaaacaaagt atttatgatt
     3061 ttcaacacaa aaggtttcca ttccagaaaa aatgacgttt cagattcgtt tgtaattgat
     3121 tttaaagaaa ctgttaatac atttggtatc gaatgaggtt acgctcttta ttcggtcttt
     3181 caagtggctt aaatgatttt ttagagggga aggggtgtag gaatgctttt tttaaaggtt
     3241 attgcatata ttttgttaag tataggagtt tgtacagttg ttttagcagg aatagccgct
     3301 attgtaaaga aacaaatgat aatcgcaaat ataaatctat tattggccat gtattatttt
     3361 tgttcgggaa gtcttctgta tttgtgcacg ttatgggaaa cacaagatat tttcctacaa
     3421 gcctttttga ttttaattgt aggaattacg atcatccgat taagaaaaag ctggtatgta
     3481 ccgcaaatac gtactcttca aaaactacaa gaagaagcga caaataagaa tgatctgtga
     3541 ggaaatccat gaaaaaagga gtggagaaaa cttgatacat caatatgaat tgaacttttc
     3601 agtgatgtat agtggcaagg taacaggctc acaatctaca attattccag caagttcttt
     3661 agaggaagca aatgaaaaat tacaatcaga agtaaagcgg cgattaggaa aatgcagtat
     3721 aaaagtgaat acggcaagtt tatgtgtttc ggaggatagt cggtatgtaa tcgaacaaaa
     3781 ataaaagagg aaaagtcttg tttctacagc aaggcttttt tattatttca tgagctgata
     3841 ttgacgtgaa attttttatt gtaaaagggt attaagttgc ggttttgaaa gctgtataat
     3901 ttgttgtttt tttgagaggt aagtgttaaa aagtgttgaa atgacaaggt ttttccgtga
     3961 tacaggtata tgtacttaag ttatgcaccc taaaatagac ttaagcacat atatctagat
     4021 atatgtgctt aaaggtatgt ggctattatt atgtgaaagt tggagagtga ttttaaaaaa
     4081 tagcgcacaa agtccttttg tttggataag aaatgaagca aaatggtgct ttgaatcatt
     4141 ggattggata gaaatttaag tgtattggac aatattttat gaatgtatgt attggaattt
     4201 ttgttggtat tttgtatact aaacgtgagt ttttcttaca gtaggcaatc tttcagtttc
     4261 tatgaaacgc aactaatctg ttaattatgt atggtgtcaa acaagctctt atgtcaatgg
     4321 atataagagc ttgtttgcat gtgtatccct cttttatgta caatgaaaga aaaacatctt
     4381 atgagatggg gagaggaaaa cccatgtcca atcaacaatt agtgaattta cgcattgatt
     4441 ttgcttttaa acaattattt ggcacaagtg gaaatgaaga tattctgatt gcttttttaa
     4501 atgctctgtt acaagattct ttagaatccc ctattgtttc cttacaatta gaagacccac
     4561 acttgcaccg ggaacatgaa gaggacaaat tatcgatttt agatatttct gcaacattag
     4621 atacgggaac aaaggtaaat atagaaattc agctcaataa taatcatgat atgattaaga
     4681 ggagtttata ttattgggga aggctataca catcccaact acaaaaagga atgccatata
     4741 gttctcttca taaaacaatt accattaatt tattaaattt tgtgatgttt tcagaatatg
     4801 aagcattcca tacaacagga gtcttatgga atcaacaaca acagaaggta ttaagtagtg
     4861 atatcgaagt tcacatcgta gagattccaa aactcatgca acagtggcga aatgaacaag
     4921 taaatccctg ggaagattca tttgttcgtt ggttgttatt acttccagcg aatgaggatg
     4981 aacaattaac ccaaacattg gaggatattg cgatgaacca agacccaatt ttacaaaaag
     5041 cgatgaataa atgggaacgt atgagtcaag attcttcttt cagacaagca tatgaagcaa
     5101 gggaaaaagc gttgatggat gaagctgcaa agtttgccca tgctcgcaat gaaggaattc
     5161 aagaaggaaa aatacaaatg attaaaggta tgcatgaact tggcgtacca attgaaacga
     5221 ttgcaaaagc aagtaaatta agtatagaag aagttcaaca tattttaagt agaaattcat
     5281 aataaacaac taagaaaaca ggttgaattt tttaatctgt tttcttagtt gttgaaattt
     5341 atcggttcat tctttggtta ttattacttt cagggattga agatgaataa ttaatccaaa
     5401 cattggagga tattgcgatg aaccaagacc caattttaca aaaggcactg aataaatggg
     5461 aacgtatgag tcaagattct tctttccgac aagcgtatga agcaagggaa aaagcgttga
     5521 tggatgaagc cgcaaagttt gcttatgcag aacaaaaagg gattgaaaag gggattgaaa
     5581 aaggaaaaat gcagcttatt cgtggtatgc acaaaaacgg aatgccaata gaagatattg
     5641 caaagtttac aaatttacac atagaagaaa tacgaaatat tttacaatcc taaatgatta
     5701 aaaaataaca cctacagtat ttgtaggtgt tattttttaa tggccaccgc caccaaattc
     5761 gtaatgatag cggatattca tatggatatg ctttcttcaa ccacacattt tttacatttt
     5821 aaacaacttt gcaacagaac cttctgattc atcttgaatt aatttaactt taactagctg
     5881 tttgtagaaa atttctttac cttatgattg gactttgtaa aatagctctc atattttaca
     5941 aagtctattc attatgaagc tatccaatca taaaacggaa ctttccctgt atattcatgc
     6001 tctgaaagtg tacgagtgat tatacttcta tctagcttgt cttcttgtaa ttgttttttc
     6061 gcattttctt ttattctacg aatctctaac tcttcaattt tattaactaa cgccgtgatt
     6121 aaatagtccc taaaattaga gattttccct tggttgtatt tatccataac tttttttaat
     6181 acagctgtaa agcttcgatc tgttaaatca tcttttgtag cttctctaag agtattaacg
     6241 attaaattta tttgttcttc ggttagagaa gagaaacttc gcttatcatc atcaaatttt
     6301 gctatatcat ttataaatat attggtattt tcttttttag tattttttcg ttggtatttt
     6361 atattgtact gaaaatccga attcgggttt tccacattcg gattttcagt aagtggatta
     6421 ccgaacgcca cctcaactac atatccttta aacatttgtt cttggattgt ttcatttaac
     6481 atttcagcaa cgtcttcttt tatttgtcca taaatgtaga tttgttcttt atatttccct
     6541 ttttctaata ctttaacgcg agcaacgtat ttgttatgta ttaactcttt aagtgcacta
     6601 tagtgtgcat cacgtccatt ttttgagcgc ttaataatat caggcatggt aaccttccaa
     6661 tatccgttac gatgtgaaca aaactgaata agaagatatt ttgccattcc tgttaggtta
     6721 caatcgtcaa gtaatgcgtt ctctacaacg ctatgtccgc gttttcgcgc atgtttaaat
     6781 atatcatttg ccataataaa aaatcctcca attttcatcc cgacaaaaat tggacatgac
     6841 aaaatagaga attcgtattt acgttttttt ttagttatga taatatttaa gtatcataac
     6901 taaaaattgt atttacaaat cctctgtttc cggtttttaa atagtatcgg tcgccaaact
     6961 gtcaactatc taaaaacttc cgtcgggggg tttttttagt ttatttaaaa atatttgttt
     7021 aaaagttctc gtttctatcc ttcatcttag cagattactg acgaaaaatg aagaatcaag
     7081 aagaaaaata tggaagaata gtataatcct cctttctata tgttttagtt ttaatccagt
     7141 tttaattaat atatattgct tctataaata aagaagtatg gtttttttcg tacagcccaa
     7201 caaagtattc tatgaataga aacggtacat agcattaaaa taggataact gtctttacga
     7261 gacaaatcta tctaaaatca aatgcagtcc attcattaac cttgttaatg tttgaatgta
     7321 atgatgaaac aagttccttt cccttcttca cttttaatat cgatatatcc gtcatgggat
     7381 atgatgattt gttttgcgat ggctaaacct aatccagaac cttctatatt ctttgtatta
     7441 cttcctctaa aataacgctc aaatacttgc tctaattctt tttttggtat gcctggtcca
     7501 ttatcttcaa ttataatttt tgtggttttt ttagtgttac atatctttac tgtaatatgt
     7561 gttccttcag gagtatgaac tatagaattc atcatgatat tatttattgc tcttgttaat
     7621 agtatttcat cgacttttaa aataatattc tgttgatttg tagagaaatc aaatgttttt
     7681 cttttataag acgggttgtt aagacaggta ataactaact ctctaactat ccctacaata
     7741 tctttatctt ttttttctaa agggattgta gcatttttca attgataggt gagtcttaaa
     7801 tcgcctatca gttgttctat gtatagggct ttctttttaa ttaccgctac atattctttt
     7861 cgttcctcta tagtaaaatt atattggtca tcagtaagca gttcactgta gcctttaata
     7921 gaagataaag gggtttttaa atcatgagta agattagtaa tccattcttg tctcatgatt
     7981 tctagacgtg atcggtcatt ctctacattt tttagtttta tagctaactt atttaaaatt
     8041 gtaaatacat ctttaaatag gcccttattt acatcttttt gcgtatataa cccattaaat
     8101 aaatttgtaa tgttatgaat gagaaccaat acaggttttg caaaatacct agcgataaaa
     8161 tacgaaaaaa ttaataagca taataatgca gaacctattg aaattaaaat accataagga
     8221 taaaaactaa ggacattatc caaatttaaa taaatcatat atcgagacac tttgttagaa
     8281 ggaaatgcta ttaagtaact ccacttctta tcttctattt caacttcact aataaaatag
     8341 gtatatccgt ctaccgcata cttatataac atagcaatat cttttgcatt gtagtgttgt
     8401 ttagatttat tgggtgcata catatcacga acaacattgc catttgaatc tataatttga
     8461 agccaagcgt tgttcgcatt taaaatattc tttccctcat tagttataga aatatcttga
     8521 ttatctagat ttaaatattt tccaaattct aatgcaatgt tttctggagt agattgtttg
     8581 taattatttg aaccttgact aaacacaaaa taagtagcaa ttatgaattg gacaataaat
     8641 aaaatgaaaa ttagacttat aattgaagct ccgtataata atgtgatttt caatttcatt
     8701 ctacgttacc ctcgatgctc atcttatatc ctagtcccct aacattgaga atatattttg
     8761 gattagaagg attgtcttct aatttttccc tcaaatgcct aatatggacc ataataacat
     8821 tttcacaacc agtacattct tcattccaaa cgctcttgta aagttgcggg agactaaata
     8881 cctgattggg attcttgata aggtataaaa gaagatagaa ttcttttgct gttaaagaga
     8941 taggtatatt gttttttaaa acagtacctt ttttttcatt taaaacaaca tctccaaaat
     9001 tatacaaacc tttatctgtg tttttttctt cctgatggtg atactgttct cggcggaaaa
     9061 atgctttcat tttaaatgca acttctttcg gactaaaggg tttggtaatg taatcgtccc
     9121 ctccgagact taatccaatt aaacggtccg agtcttcttc tttagcagat aaaaagaaga
     9181 taggtgccaa tgtgatattt cttagttgtt ggcatacgct aaaaccatca atatcaggta
     9241 gcattatgtc taatataatt aaatcgtaat caacttctct acacatctgt attccttttt
     9301 ttcctaatga agccttatca atatgataaa acccttcttt tctaaggaca atttctaata
     9361 tctttagaat ttcctcttca tcatcaatta ataatatttt tttagatttt aaatatttag
     9421 gatcaataaa caagttcttc accttctcaa tatttattcg taagtttctt ttttgaattt
     9481 ctcacaatgt gaaaaccaac atattccaat ataattttaa agtaatagta tccatatatt
     9541 caagttttca ttgttttggg ttatattggg attccctttt aattcaataa aaagtaataa
     9601 aaagtaataa aaagtaataa aaagtaataa aaagtaataa aaagtatatt ttttcaaaat
     9661 aaagggttta cattaccata aattagtatt atactttgaa atgtgatatc gcaaaatcta
     9721 aataataagg gtgataaata tggaaaagaa ttttgagcta aaagctttag aagcaattaa
     9781 tgatttaaca gatgcagaat tagaaaacgt agtaggcgca gacaaaggtc aattcgacac
     9841 aatttctcat gagtgtcatt ggaatacatg gcaattcctg ttcacttgct gcagctaagc
     9901 tgaatctaca agaaaagaac gctcttattg aagggcgttc ttttcttgta gattaattaa
     9961 aaaatataaa ttactaatta tatagagtgg gggatatcat ttgttaacat ctacagattc
    10021 cttaaataat attaatgagc tattggataa ttccacatgg gctcatgcac tatatttaaa
    10081 tgagagagaa aacatagaaa ttaataattc tattaatgaa gatagcgtaa ctgaatggct
    10141 tcaaaagttt aataataata aggaattatt attagaacgt cttgatcaag aaaaaataac
    10201 atattctcaa tttacatcta tcctttcaag tccacaggta gatcacacat ataaaaaaat
    10261 ggaatggttt ttaacaatta aagaaatttt tttacaaacc aaggacgagc acaatgatgg
    10321 agaattcgat aaactttttt caaaagacgt tccttttatt tcttttataa tcccatttgt
    10381 taattatgta aaagagaaaa tatttaaaga aatagatcaa acaaatacat tacatatctt
    10441 tgaaaaaaaa tgcatagaag aaactatagt taaattggtt tcttcaacta ttttcaagta
    10501 ctcattaaaa acattgatat atgaattaaa taaagcaaga attcaaaacg aattatctgg
    10561 agatacccca gaggagagat ataactactt cgagaaggag aaaattggta aatcatctca
    10621 aattttagcg gtactttctc aataccctgt attagctcgc ttaatatctg aagctataag
    10681 taatatcata aataatctaa ttagatttat aaatcaattt acgaatgatt atagagaaat
    10741 tgaaactacg tttgagataa gtattaccaa agtaattaat attcaggcgt tgggcgattc
    10801 acataataag ggtcaacatg tcctaaaact tgactttaat gataaccaat caataattta
    10861 taaacctaga tcattatcga ttgatataca ttttcaacaa tttttaaatt ggataaatga
    10921 aaaaaatgaa attcacaact ttaaaactat aaaagttatc aataaaggaa cttatggctg
    10981 gcaagaattt gttacatata aggattgtac tacagaagaa gaagtacgtc gtttttatga
    11041 aagacaaggg caatatttat gtgttttaca cttcttaaat gcaacagatt ttcactatga
    11101 aaacttaatt gctcatggtg aacatccaat gttaatcgat ttagaatcgc tatttcatac
    11161 tacaataaag aacaatcaat ccttaaaaag tccagctaat cgtaaagcca taaatatcct
    11221 aaatgattcc attgcaagaa ctggtctatt gccaattttt gtagataatg atttgtttga
    11281 tattgatgtt agtggtattg gtggcggaaa gaaacagcaa gtagaaagat ataaaataga
    11341 taaagtaaaa actgatgaaa tgagattgat taagggttca atatatttag aagcagggtt
    11401 aaattcgcca aaaattaatg gagaagtttg cgaggccttt aattatacac aatctattaa
    11461 agaaggattc tacaaaacat ataaattact agaaaattat aaagaggccc ttctgtcaac
    11521 agattcacca atccatgcat ttagtaaaga tagggtaaga ataatactta gaagtactat
    11581 agtatatagt catcttcttg acgcgagtac tcatcctaag tatttaaaat ctggcattga
    11641 tagagtgaaa ttgtttgatt atatgtggtt actagttgat tatatttaca atcgaaaaaa
    11701 cgcggctata tgtgaatgta aggatctatt agcaggtgat gtcccttatt tctatgtaga
    11761 cgttgattcc actaaaatat taacccatca aaattttgag ataaaagata tgtttgcaaa
    11821 agatagtttt aatatggtat tagaaaaaat aaaaaatatg ggcgaagaag attgcaatcg
    11881 acaattagac tttattgaaa agtcgctatt aacaaaatat tatttggata tcaataatat
    11941 gaacaaagct attgaagatt ttaataagaa gtcttcttac gaaggtacat tgttaaacaa
    12001 agaggcattc ttaacagaag ctattagaat tgctaatgta ttagaaaaag aggcaatctg
    12061 ggcagaagat ttttccgatg taacttggat tggaataggt atgagttcag atgagaaatt
    12121 aaactataaa gcgatggata tggggatata tgatggtatc ttaggtatgg ccattttctt
    12181 tgcatacgtt ggaaaagaaa gtgggattcc taaatttaaa aaaattgcaa aagcctgtct
    12241 acaaacagct ttaaatgaga agaatgctac aaaaaaagca tacatatctg ccttttcagg
    12301 atattcttca gcggtttatg tgttaactca tttctacaaa ttatggggtg aaaaagaact
    12361 attagatgaa gcaatcaatt tcattaatga aattgaacca catatagata aagatacgac
    12421 gttcgattta cttaatggaa gtgcaggaac tttattagta cttttaaact tctataaagt
    12481 cactggtttt caaaaggctt tagatattgc tataaagtgt ggcgatcatt tattaaaaaa
    12541 tgccgtgaaa gtaaatggag gcacagcttg gactatttct cctaagcata cccccttaac
    12601 aggattatct catggaacat ctggcattgc attagctctt attcgattaa ctgaagaaac
    12661 aggcgatcaa aattatttaa atgcagcatt acaagcttta aattatgaga atagcacttt
    12721 ttcttctaaa gaaaacaatt ggctagatct tcgtcaaaac atgaataggg atactcctaa
    12781 atctgttata cattggtgta atggaacggt tggaatagga atggcacgat tgaaaatctt
    12841 agaacattat caatcggaga tatttgtaag agatttggaa aaatctatag aaattactat
    12901 ggagcgtggt tttttaaatc ctaattatag cctttgccat ggtgatttag gaaatttaga
    12961 tttactatta ttagctgcta cacgtattga taagtataag ccattgtcaa aatttgttta
    13021 tgaaaaagca agtagtatgc ttcaatatgt acaggaagat aatcaaaatt ggaagtgtgg
    13081 aatccccggt ggacaacaaa ctcctaactt tatggtaggt ctttcaggaa taggttatca
    13141 gttgctacgt ctttataata gtgaactacc atccgttcta actctagaat aagatataaa
    13201 aaagtatggt actcaatata aggacaatta tattgattgc catactttta ttaaatttta
    13261 acgattttaa tttttagggg gaaaagattt gcaatgaaat ggaatataag aaataaaaaa
    13321 tcaaaagttc caattgttga acaaatgagt caatatgaat gtggaatttg ttgtttgaat
    13381 atgattttaa agtattataa ttatgaaata aaactttctg aattaaggcc ttattttgaa
    13441 gagagtagga atggtactac tttgttaaaa ataaaacagg tagcagaaaa gtttaacatg
    13501 cattgtattg gaaaaaaggt atcaatagat tttctactag aatatcaaga tttgccatta
    13561 ccatttatgg tgtttttcga gaataaacat tatgtggttt tagaaaaggt tacgggtaca
    13621 catttcttta ttgctgatcc agctatagga catgtaaaga tgactaaaaa agagtttgaa
    13681 gagaaatatt caggtaccat ttttattatg attcctaatg aagattttgt tcccaaaaaa
    13741 caaaaacaaa aatcaagtat aaaaaagatt atagttgaaa acaaaaaacc attattatat
    13801 ttagtactgt tttcacttct aattcaatta atttccgtag gtgtaccaat aattatgaaa
    13861 acatctatag atttaattgt aatgcaaaaa aaatacgcta tgatttcaac atttataatt
    13921 tcttttttaa tactttgtat ttttcaagtt ggtttcaatt tgtttaagga tttcatactt
    13981 attaaattac aaaatagttt agattataaa cttacaaata aatttgtatc gcatctatta
    14041 aagttaccat acaaattttt tgagaatcgt tcccgagggg acttaatctt acgtgctaat
    14101 agtaatgtta gaataaggga gttcttatct caaaatctta ttatgtcttt aattaatatt
    14161 tgtttagtat ttgtattatt tacttacatg ttcatagaat cgcgtctttt agcattggta
    14221 gtattattaa ttgggattat acaagttctt accattgtat ttacaaaaaa taagctgaag
    14281 tatttaacaa aatcacagat tactagccaa acacgttaca gcagttttat gactgagatg
    14341 ttaggtggaa tgtctacgat taaatcttta ggtatcgaaa ataatatata taaaaattgg
    14401 gaggaattat taagtaagca ggttgaagca aataaaaata agtcctattt tcaattgaaa
    14461 gtagatacta ttacaaaaag tttatttttt gttgctccat taattgtcat atgtataggt
    14521 atttatcaag ttgttaatgg acaaataaca attgggacgc tttttgcatt tcaatcagta
    14581 acaatttctt tcttaacacc cctcaattca attgctatgt tattaaatga tattgtaact
    14641 acagaaacat tattagatcg aattgatgac gtattaacag aagaaaaaga gcctactcct
    14701 gataatgatg tattcattaa attaaaaggg gatataaagc tggacgatgt atcatttaga
    14761 tatagtaagt ttggaaatta caatttaaaa aatatttctt taaatatcgc atctggtcaa
    14821 aaagtagcaa tagtagggaa gtctgggtca ggaaaaagta ccttagcagc actactatcg
    14881 gggctatata cacctacaca tggtaatata tattttgatg atactaatca tagtactctt
    14941 agtaaggaaa ctttgagagg gaatataggt gttgtactgc aagaaaactt tctatttaat
    15001 aaaaccattt tggagaattt aactattcat aataatgata ttaatatgga tgaaatttta
    15061 tttgctacta atttggccca aatacatgaa gatattcaag ttatgcctat gggatatcat
    15121 acagtcattt ctgaaggtgg atcaaatata tctggtggac aaagacaaag gctttcttta
    15181 gctagagcat taatttctaa gccatcaata ttaatcttag atgaagctac tagtgcttta
    15241 gatacgataa cagaaaagaa gcttaatgaa ggaattcaaa acttaaattg tacaagagtt
    15301 gtaattgctc atcgtataag taccatcata gattcagata taattgttgt tatggatcaa
    15361 ggtgaaattt tggatagtgg aacccatgag cagctacttt tacgatgtaa ttattataaa
    15421 gatttctatt atagtaattt tcatgatagt aaacaattac aaaaaatgta atacttattc
    15481 tcctaattca atgtaagcaa taacatacgg acatttcata tttaaatctc taacagattt
    15541 ttagatacga aatgtccgta tatttatgac ttacatctta ttgaacattt aatgtgaaat
    15601 tttaaattat aaaatgatag tagaaattat ttaatgtcct tacgtgtcat tctgcgtata
    15661 cctataaata aaaatactgt tgtgtaaaaa atgttcataa tgaaaaagaa aaatgtattc
    15721 ttgaatcctt gaataccatg tagttttatt ggatccatcg ctaaagctga gtaagaaaaa
    15781 ggccatatat atccaatgcc cattaaataa aaaataatcc ctaaaaatgt aaaagctact
    15841 ccaataccta ttggaactac aaaactcttt aatgatgtag aaagccatag ctgaagagat
    15901 gctatagaaa tagttccaat ccaagcataa aatacccatt taagtagtac catagggaat
    15961 ggatgagaaa aatctaaaaa attccctgaa attatataga gtattactaa aaatatctgg
    16021 gtaaccaaag aaagtaatga gataacaata agctttgaaa ggtaaatatt agttatagaa
    16081 ataggcaatg ataatatttt attccaatta ttacctgaat cttcatatct gcaaaccaga
    16141 gaactataaa cacctattaa tataggaaat aaaaacatac tatacaacat acctatttgt
    16201 gtccaagctt gcatccattc atttttacca gcacctgcaa gtacttctcg attaaactgg
    16261 aaatttagta gacccaataa gatacaaata aaaggtatac atagcataat aatccacatc
    16321 ttagatcttt ttaattttaa taattctgta gaaatagcta gtctaagcat aaaaacaatc
    16381 cttccttagt tagtatcttt tttcataaaa tgttttaatc ctactagaat taggatgatg
    16441 cctactacaa tacttaaaaa taaattggat aatgaattaa catttggttg atacgtcatt
    16501 tggtttccga ctactttaag catgagagga ccagtaattg atggatacgt ccaaataaga
    16561 aatttactga taggtatcat ttgtcccaaa taacctaaaa aagatccaag aatacctact
    16621 gttaatgaaa atgcttgatt ttttattaag acagaaaccc aagtttgcag agctacaatc
    16681 gcaatactag aaatccaagt tgtcgctagg aattttagta ttaaatttac tggaaaagat
    16741 ccagggtaat ctaagacatt acctattatt aacatactga aaaataaaat aattagaggt
    16801 attaaaagta aaatcatagt cgtaattatt ttacatatat aaagtgatgc tttattaata
    16861 ggcgtagcca atagcatttt ccatgtattc tctttatgtt ctacatcaac aagcctagat
    16921 acaattgtgg caatcataat tggcacaaat aaaccgttta gtatgccgaa gtttgatatt
    16981 aagttatccc aaatatgaaa ttcctgacgg gcctttgctg ttaaagcaaa aacccaagca
    17041 atctctaata tactcattaa aataataaca aatataaaac gttttctttt taacttaaga
    17101 aattcgcttc ttaataggga tatcattaca gacttcctcc tttagctgtt aactcaagga
    17161 aaatatcttc taatgtacgt ttctcttctt caattctata aactgacata ttattattta
    17221 tcatcagtcg gtttgcttgg gcaacttgtt cttcagtata tgtatttaaa actagagagt
    17281 caccttctat tttggagaaa atctcatttc ttaatagaat tttgtgggca tcgcttaagt
    17341 tatcgacttt cattctaata attgaattac tttgctgtct taattttgct atgtcatcct
    17401 gaaaaattaa aaccccattt tgaataattc caacttgagt agctatatgg tctatttcac
    17461 ttaataaatg acttgaaata atgactgtca taccatattt actaggtaat tctttaataa
    17521 gttcacgtat ttcatgtata cctgatgggt ctagaccatt agttggttca tcgagaatta
    17581 aaagttttgg aaatgctaaa agtgatgagg caatacccaa cctttgtttc atacctaatg
    17641 aataattctt tactaatttc tctttttgat tttttaatct tactatttca aggacttcat
    17701 ctatattttt tcgtggaaca ttaagcattc tgcggattat ctctaaattt tcatatcccg
    17761 ttaaatgtcc ataataagaa ggggattcaa caagggaacc aatttgcttt aaaatgttta
    17821 gcctatttgt ttttaaatct tggccaaata ttttgatgtc accgtttgtt ggtttgacta
    17881 gtcctaatag catctttata gttgttgttt ttccagctcc atttggtcct aaaaaaccat
    17941 aaatctcacc ctcgttaact tttaaatcta tattatttac attaaaagta tctccgtgtt
    18001 ttttggaaag gttatgtgtt tgcacaatat atttagacat ataaatacca cctcatcatt
    18061 ttatatttat taacttaata tcattataca atgataatct taagttaaaa ttcagcttac
    18121 cttaagatta ccttatgtat gtaaataaat tatctatttg gggtaccgcc cacattttaa
    18181 tgaaaatata cgctaagcaa atttcgacat aaaagaagcc gaaaatagaa atttattgaa
    18241 ttttataatt aaaaaagcgt tcattaagta ataaaattac tcgaacgaac acctttttta
    18301 attattcagt ttgataatag aattaatcaa aaatcacatc aatatcacta atataattac
    18361 tttgtttctt taaagaatcc tgccaaccaa atgacatgaa actcacgcta agacattttt
    18421 gagtagaaaa agccttgact atcttatgct aagaaaaatc acttacctaa aacaaaaaag
    18481 actgtatcca gatgctacat gttactatgt atctggtttt tatttatatg attatatttt
    18541 acctacctgt atgcctaaaa atgctaacaa tataccaatg atataagaag cacctatgta
    18601 tagaaagaaa atcccccatc tcttatttgc accaagttga atagactcca atttaaatgt
    18661 agaaaaggta gtgaaagctc ccatgaatcc tgttcctaat agtaattgcc aacttttatc
    18721 tattccttta ccaaggatat accctaatag aaaagctcct gtcaaattaa taagaaaggt
    18781 agcaatcgga aaagatgata aatttctttt cttgaaccaa ttactgatac caaagcggga
    18841 gatagcacca aagaagcctc caattgccac caataaagca tgatattctg tcattacttt
    18901 atgcctcctt ttgactgtag aacagatttc ttttgagtgc gtttcacaaa taaagtaatt
    18961 ccaagcttat agcctattcc agacatcaga agtccaccta acatactgaa acatacatat
    19021 aaaattgcaa atatccattc cgcatggtta attaacttaa cagtttccac actaaatgtg
    19081 gaaaaggtag taaatgatcc tacaaaacct gttccaattc ctgtgacaat ctctgaagga
    19141 aaaatgttca agcgggaaat ataagtagta atccaactta atacaaaaca tccaattaaa
    19201 ttgattaaca atgtagctaa agggaatgaa tgatgccaaa atgtatcaat atttaatcct
    19261 aaataataac gagaaagagc acctaatacc ccagctatac caacaataat atacaccatt
    19321 ttcttcacct cttttatagt ctgctcaaaa aaatagactc ctaccagtaa atacttgctt
    19381 actggtagga gtcatcagct ctaaggcaat taaggcgaac tccatcgccc atgcagttat
    19441 attagctatt gtagcaaata aatgttattc tgcctactga aataagaggt atactttgag
    19501 gttcatacca aaaaaattat cactactata gagaggcatg gttaataaaa cctcaattat
    19561 ataattagta aaaaataaga tgaaataact aaaataactg cgataactaa ggttgatagc
    19621 catataatca atgtggtatg tgcacgaaat gtttgtgagt taatgttttg gcgtttaatt
    19681 aaatattgta gtgttgcaat aataataata cctatgccag caataactga tcctattcca
    19741 attccaatcg caactttatt gttaaatgtg gaaagctctt ttcgaacggc taaatgaaga
    19801 ttagctacaa gaaatcctaa accagcaata gcaatggcag tacgtaacca agctaaatat
    19861 gttctttcgt tagctaaatg ttgctgaata tattttgaat ccactgtttc gaaggctttt
    19921 tctgtcgttt tctgttgtct cattacatag tttcactcca ttaatcagca gtatagtgta
    19981 ggtgtgcgta tcctttttta cgtctatacc atgcaataag aatactacaa atgatacacc
    20041 caattgagac taactgagct atccttatat gagatgttaa catgaggcta tctgtacgta
    20101 agccttctac aaaaaatctt cctacggaat accataataa ataagttaga aagatttctc
    20161 ctctttttaa attagctctt cttaataaaa gcaatagagc tacgcctgta atattccaaa
    20221 tagattcgta tagaaaagtt ggatgataat atgtgccatt tatattcatc tgattaataa
    20281 taaattctgg taaatgcaaa gattctaaaa aacttttaga tacaatccct ccgtgggcct
    20341 cttggtttat aaagtttccc catcgtccaa ttgcttgtcc taaaagtaaa catggagcta
    20401 aaatatccgc cattttccaa aaagaaagat ttcgtttttt tgtaaaccat atagttgtta
    20461 atacagcccc aataatacca ccatggattg caattccgcc atgccaaatt gcaaaaattt
    20521 cccctaggtt atctttataa tagttccatt caaagaatac ataatatatt cgtgctgaaa
    20581 caattgagat aggtaaagcc agaaagatta agtcgtaaaa tatatctgaa ggaaccccac
    20641 gttttttccc ttcatgagtg gctaagataa accctaatat agctcctata ccaataataa
    20701 ctccatacca atgtacagca atgggcccta agtgaattgc aataggatct aaggggtggg
    20761 tttgttctgt cattaaaaag cgcctccttt tatttaaaag tataacaata tatacatttt
    20821 agattatgtt tattataaca ttgaaactta cccacatata aacttccttt tctatcattc
    20881 gtattaaatt gcaaatgata tcccaagagt attaaacatc tttacgccgt cccaaaaacg
    20941 attattttcg ggacgatcga atatcaagcg attttcgcta atttttttcg aaaaactttc
    21001 ccaaaactca tctcaaaaac tctgtcgctg atacgtacgt ttatgaacca taatatattg
    21061 gaataaaata actttatcaa caaatgttat ggataaatat atacaaagag cagcagttca
    21121 aaaagtaaaa tggtgattca agttgaaaaa ctactcattt gggtgttttt ttctctgtct
    21181 tacatacaca aaaggagatt gcatcttgaa tattatcgac ttagaactag tacgaaagcg
    21241 aaaaataaag ggaaataaaa tgattacaat accaattatt gaacgggtct ttaaagtaaa
    21301 tgaagaaatt cagtttgaag taactggtga aaaagaactt cctattgctt ggctagaaaa
    21361 ggaatagata cttctgttct tgtttatttt tttataaaaa cgaaagtgga attttgaata
    21421 tcagtcatat atttttcata atttaatgca aataaagtaa aactttaatc agtaggaagg
    21481 ctattcatcc ccgcagatta atagctctca caaatgaggc ttttacgaac agttatacaa
    21541 tcaataaata aggaaaagat ttttatcatt accttgaatt ctttttacaa atacgcatcg
    21601 aaccacaaaa agaaccagct tacaactggt tctgattcag tgtacgttca tattccttga
    21661 ttattttata aaaggtattt ttctttaaat ctaacatttc cataaattga actcctgtta
    21721 tttttttatc tttccacttt ggataagttt cttctattat atatagctgc ttttggctta
    21781 aggatgagag gttaaattga ggacgcccta aatgttttcc ttgagattta gctaccgcaa
    21841 ttccttcagc ttgtcgctgt cgaatttttt tgcgctcttg atctgcaaca taggaaagca
    21901 aagataaaaa ttggtcttcc attaatcggc ccatatcacc catctcacga aatttccggc
    21961 tatcaaacag ggtttcattt tctaaaacta cgatatcagc ttgtaattgt cttgttatat
    22021 acttccattc tgaaattacc tcatcataat tgcggcccat acgatctaat gcatctatgt
    22081 agacaatatc acctgtactt aaaatttttc gtaataattg atattgagga cgatcaaaat
    22141 gtcgtccact tgctttatca acaaaaatgc gtcgagcttc cactcctcgt tccatcatct
    22201 tatgtaattg acgttgttca ttttgatctt ttgtacttac acgtatatat ccgtaaacat
    22261 ttgacatttt ttatattctc cttacatttg ttaccacaat tatatcattt ttgtttataa
    22321 agatgttgat taaaaataaa cgtttataaa tctaatttaa tcacctttgt aaacttgata
    22381 tatcaacgtt tcatagatag agcctcttag tttataaaag tataccttta caaacatcat
    22441 gcggaagaaa aatacatttc gtattaatta gtaaaacaat caaaagtaag gtgaattata
    22501 ccatttgttt ggtactagat gtaatttggt ataattgtat ttaaacaaat tattgctaat
    22561 aggtagagga aggaatatag agagtgaaaa aaacatttca ggccaaaaga ttcttaatat
    22621 caattctaat ggtagcccta gtgttaatta tttattttgt gattcaatca attgtatcac
    22681 ccgcaagagg ggtaacaaac caagacaatc caattcagct ggtaggcgaa cagcccaacg
    22741 ttgagataaa caaacgagta cctaatcaat ttaacggtca aatacggaaa gttgcatatc
    22801 ttacatttga tgatggacca ggaaagtata cagctgagct tttagatata ctaaaacagc
    22861 aagatgttaa agtaactttt ttcttaactg gtaagaatgt aaaggcatat cctgatttag
    22921 taaaacgaga aaaagtagaa ggtcattatg tgggtatgca tagcatgact catgatttca
    22981 aaaaattata tacaaatggt gactatgtta atgaaatgac aacaaatcaa aatttaatag
    23041 cgaacattat tagagaaaaa ccacaattaa cccgacctcc ttatggttct atgcctggat
    23101 taaatgaaga acttcgtaat aaggtagtag atggtagatt taaagtatgg gattggacaa
    23161 ttgactccct agattggaag tataataacg ta
//
