LOCUS       NZ_CP044407            28570 bp    DNA     circular CON 28-JUL-2024
DEFINITION  Actinomadura sp. WMMB 499 strain WMMB499 chromosome, complete
            genome.
ACCESSION   NZ_CP044407
VERSION     NZ_CP044407.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura sp. WMMB 499
  ORGANISM  Actinomadura sp. WMMB 499
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Draft genome of Actinomadura sp. WMMB499
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2019) Pharmacy, University of Wisconsin-Madison,
            777 Highland Ave., Madison, WI 53705, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. Oct-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008824145.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 05:00:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,413
            Genes (coding)                    :: 8,251
            CDSs (with protein)               :: 8,251
            Genes (RNA)                       :: 110
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 64 of 162
            Pseudo Genes (incomplete)         :: 108 of 162
            Pseudo Genes (internal stop)      :: 10 of 162
            Pseudo Genes (multiple problems)  :: 19 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:12:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6915873
            Orig. end                         :: 6944443
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044407.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Genome not circularized.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..28570
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="polyyne"
                     /region_number="20"
                     /rules="((PP-binding_2 or PP-binding) and delta9_cd03505
                     and delta12_cd03507 and FAAL_cd05931 and (4HBT_2 or
                     Thioesterase or PF00561))"
                     /tool="antismash"
     cand_cluster    1..28570
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PP-binding_2 or PP-binding) and
                     delta9_cd03505 and delta12_cd03507 and FAAL_cd05931 and
                     (4HBT_2 or Thioesterase or PF00561))"
                     /kind="single"
                     /product="polyyne"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..28570
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:18570](+)"
                     /cutoff="10000"
                     /detection_rule="((PP-binding_2 or PP-binding) and
                     delta9_cd03505 and delta12_cd03507 and FAAL_cd05931 and
                     (4HBT_2 or Thioesterase or PF00561))"
                     /neighbourhood="10000"
                     /product="polyyne"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..18570
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((PP-binding_2 or PP-binding) and
                     delta9_cd03505 and delta12_cd03507 and FAAL_cd05931 and
                     (4HBT_2 or Thioesterase or PF00561))"
                     /neighbourhood="10000"
                     /product="polyyne"
                     /protocluster_number="1"
     misc_feature    75..89
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.88"
                     /tool="antismash"
     gene            complement(458..883)
                     /locus_tag="F7P10_RS31145"
                     /old_locus_tag="F7P10_31145"
     CDS             complement(458..883)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040285.3"
                     /locus_tag="F7P10_RS31145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31145"
                     /product="DUF5980 family protein"
                     /protein_id="WP_151014789.1"
                     /transl_table=11
                     /translation="MKSARNSARIVVGMLAVLAMSLIGAAPASAESPTWTLQDIGQKVC
                     VSTGGWDGTYVFAPVSGTWTTPITTGIRNLPPGSSDLGGSVLPPGSNDENTINGFVGVS
                     FAPAPAGDYVAEVWASDGTVTQTAPVLLRYGAPYACW"
     gene            complement(1121..2746)
                     /locus_tag="F7P10_RS31150"
                     /old_locus_tag="F7P10_31150"
     CDS             complement(1121..2746)
                     /GO_function="GO:0016614 - oxidoreductase activity, acting
                     on CH-OH group of donors [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890890.1"
                     /locus_tag="F7P10_RS31150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31150"
                     /product="GMC oxidoreductase"
                     /protein_id="WP_151014791.1"
                     /transl_table=11
                     /translation="MRSTPLPERGSTGVSRRGFLAGTGSIIGLGLLSRTGSAAAATTSI
                     GNGARVPVLVIGSGYGGSVAALRLAQAGVDVHMVEMGMSWNTPGDDGKIFANTRSPDYR
                     SYWLRTRTKQPLSNFLGFPLDKNVPRYTGILDAEEFGGITVYQGRGVGGGSLVNGGMAV
                     TPQRERFGAILPSVDADEMYDVYYPRANAGLGVNQIDRAWFDTTDCYKYARVGRKHAER
                     SDFDFVYVPNVYDFNYMKQEAAGNVPRSALDAEILYGNNAGKKSLQQTYLAQAAATGRV
                     SVSPLHRVTSVTPASGGYTVTIEQLDTGGNVTATKTVTAGKVFFAAGSVGTSKLLVKLK
                     ATGALPNLNGEIGKGWGDNGNIMCGRANHMWDATGSLQSSIPTVGIDNWDAGGAFAEVA
                     PLPTGIETFASFYLSITNTPHRAQFSWNASASRVDLNWQTAWKQASIDRAKTIFDKINR
                     KEGTIYRTDLFGVYKIWGDHLTYHPLGGAVLNKATDNHGRLHGHPGLYVIDGALIPGNT
                     SVNPFVTITALAERNIDSIIGADF"
     misc_feature    complement(2746..2761)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 19.26"
                     /tool="antismash"
     misc_feature    complement(2821..2836)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.6"
                     /tool="antismash"
     misc_feature    2876..2889
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.96"
                     /tool="antismash"
     misc_feature    complement(2907..2922)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.62"
                     /tool="antismash"
     gene            2923..4002
                     /locus_tag="F7P10_RS31155"
                     /old_locus_tag="F7P10_31155"
     CDS             2923..4002
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890892.1"
                     /locus_tag="F7P10_RS31155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31155"
                     /product="dihydrodipicolinate reductase"
                     /protein_id="WP_151014793.1"
                     /transl_table=11
                     /translation="MISTVVWGTGNVGRLALRAVEAHPALELSGVIVHDPGKVGRDAGE
                     LGGLDRTLGVAATDDAGAVLAAGPGAVVYAASGDIRPDEALADILRAIRAGAVVVSPAL
                     YALYDQRNAPAEMREAVLAAIEEGGGSLFVSGVDPGWGNDVLPLLVSGLGHTVDVVRCQ
                     EIFDYSTYDQPDSVRYLVGMGQPMDYEPPMLAPSVPTMVWGGQVRLIARGLGVELDEVR
                     ETLDRRPLDATVTTASMGDFEKGTQGAVRFEVQGIVGGEPRIVVEHVTRIHPSCAPDWP
                     VPPDGDGAHRVIIEGDPRIEVTVEATDAAGNRAAGGNGTAVGRLVGAIDWLVEAEPGLY
                     DALDVPIRPATGKLGRTAR"
     gene            3999..4481
                     /locus_tag="F7P10_RS31160"
                     /old_locus_tag="F7P10_31160"
     CDS             3999..4481
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655705.1"
                     /locus_tag="F7P10_RS31160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31160"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_151014794.1"
                     /transl_table=11
                     /translation="MNIDIPGGKDPIGYVWGEMVPGIGPAAANFSMAVYAHTTLGLREF
                     EAARLRIAQINGCVFCLDWRTERDGEKVEDGFLDAVTEWRTTTAFDDRTRLAAEYAERY
                     AVDHHGLDGEFWDRMTAHYSQVEIVELSMCLGSWLAFGRLNHVLGLDAMCMLPNKP"
     gene            complement(4504..5433)
                     /locus_tag="F7P10_RS31165"
                     /old_locus_tag="F7P10_31165"
     CDS             complement(4504..5433)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017566736.1"
                     /locus_tag="F7P10_RS31165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31165"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_151014796.1"
                     /transl_table=11
                     /translation="MDDLETRELRYFVAVAEELHFGRAAVRLGIAQPPLSRAIGRLERR
                     LGVRLLDRDRRGVALTDAGRVLLREAGTALDAVAAAARRTRRAGDPERPLVLATKAGAS
                     HELLQRLLGALASDPGAAPVEVLLCEVGEQAGLLRDGRADVALMHRPYDDLAGFDTEDL
                     CVEGQVAILPAAHPLAARDRLTLADVQHVPDLPIARWPRLDGTYPDGPGPEVRTQSQLA
                     QLVALGRTLLVIPASSRAWQWPEHVAVPVADAPEVTTVIAWPSASRSREVAALVRAAAA
                     LHHPGGDQGTGPDGPADAGAGRRPPPGS"
     gene            5517..6242
                     /locus_tag="F7P10_RS31170"
                     /old_locus_tag="F7P10_31170"
     CDS             5517..6242
                     /NRPS_PKS="Domain: PKS_KR (8-180). E-value: 5.1e-08. Score:
                     25.0. Matches aSDomain:
                     nrpspksdomains_F7P10_RS31170_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019611545.1"
                     /locus_tag="F7P10_RS31170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31170"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_151014798.1"
                     /transl_table=11
                     /translation="MERVNETKTALVTGANKGIGFAIARGLGAIGFTLAVGARDEGRRE
                     EAVGKLRAGGADAFGVALDVTSDASVAGAAEAIERTAGRLDVLVNNAGIAGRTDGGAQD
                     PATLDLDVLRTVLDTNVFGVVRVTNAMLPLLRRADSPRIVNMSSNMGSLELRTGPVLAA
                     YAPSKSLLNSITVQYARGFEGTNVIVNAACPGYVATDFTGFAAPRTPEQGAAIAIRLAT
                     LPDDGPRGGFFDDAGTVPW"
     aSDomain        5541..6056
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS31170_PKS_KR.1"
                     /evalue="5.10E-08"
                     /label="F7P10_RS31170_PKS_KR.1"
                     /locus_tag="F7P10_RS31170"
                     /protein_end="180"
                     /protein_start="8"
                     /score="25.0"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALVTGANKGIGFAIARGLGAIGFTLAVGARDEGRREEAVGKLRA
                     GGADAFGVALDVTSDASVAGAAEAIERTAGRLDVLVNNAGIAGRTDGGAQDPATLDLDV
                     LRTVLDTNVFGVVRVTNAMLPLLRRADSPRIVNMSSNMGSLELRTGPVLAAYAPSKSLL
                     NSITVQYAR"
     CDS_motif       5547..5621
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS31170_0001"
                     /evalue="2.50E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="F7P10_RS31170"
                     /protein_end="35"
                     /protein_start="10"
                     /score="10.5"
                     /tool="antismash"
                     /translation="LVTGANKGIGFAIARGLGAIGFTLA"
     gene            complement(<6704..7162)
                     /locus_tag="F7P10_RS44815"
                     /pseudo=""
     CDS             complement(<6704..7162)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:TIGR02937.1"
                     /locus_tag="F7P10_RS44815"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MDMDAPDTTGRDAGGHGAAADTATRTFTDHRELLFSVVYNLLGSV
                     ADTEDVLQDAWLAWSSRDRPEVTNPRAYLVRVAVNAALARQAAISRRRETYLGPWLPDP
                     LVAGADESAERTEAVSMALLVVLETLTPLERAVFVLYEVFGYPHTEIAA"
     misc_feature    complement(7374..7387)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.19"
                     /tool="antismash"
     misc_feature    7375..7388
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.22"
                     /tool="antismash"
     misc_feature    complement(7375..7389)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.34"
                     /tool="antismash"
     misc_feature    complement(7376..7389)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.06"
                     /tool="antismash"
     misc_feature    complement(7377..7390)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.97"
                     /tool="antismash"
     misc_feature    7546..7560
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     gene            7750..8949
                     /locus_tag="F7P10_RS31180"
                     /old_locus_tag="F7P10_31180"
     CDS             7750..8949
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024945.4"
                     /locus_tag="F7P10_RS31180"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31180"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_151014800.1"
                     /transl_table=11
                     /translation="MIDEYPENGLDVRERYQKAMRLRVHHLTGRVLDMLKQAEHAYRSS
                     GTIPQQEPPQWIARSIDRALDAVTLPPAEMAATLDMPDRTGTRRGRQGVPERALLRAYH
                     LGGRELSVASAQWAMEEGVDHRDVAPLIDAIWRVTEEHSSAAVAALRGAREEIVEPSRA
                     GHLLDALLNGDEESRTVAAVARSFAVPETGRYAVVVRHPAHGGVREEDLVPFARGTRLV
                     WRRHGVTAVGVAVLGTAAATSLAGALPAAGGYRTGVSGAMEGLASLGRARQGAEAAART
                     LRGPGLAFLEERFPAAMLHADPGLARQFQAQVLAPVLALDAGRRDALLETLEAWLRAGG
                     SAGRVADDLFCHRNTVQNRLRRLEELTGRSLSAPTDVIDLGLAVQAFRQFGDEPPGRAG
                     "
     misc_feature    complement(7785..7799)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.1"
                     /tool="antismash"
     misc_feature    7786..7800
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 23.29"
                     /tool="antismash"
     gene            9038..9832
                     /locus_tag="F7P10_RS31185"
                     /old_locus_tag="F7P10_31185"
     CDS             9038..9832
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF044908.1"
                     /locus_tag="F7P10_RS31185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31185"
                     /product="acyl-CoA thioesterase domain-containing protein"
                     /protein_id="WP_151014802.1"
                     /transl_table=11
                     /translation="MTVPAIVAPGALLRSPVEGPLVPDGRLFGFGGLHGGLALALLTAA
                     MQRRAAPDAVLRGASARLHRALAGEFTVTTRVLRPGGVTTVAAEAASAEGVHVDASAIF
                     AGPYAAGGPVLAPPAPAAPPPGDCEIFRIPPEFVPISEFWEIRPVGANRPYAGCAEPEL
                     TAWVRLLEDDEAPDVHRLMLLMDALAPAYAAVLGDLRLVPTMEMSVRTGDGLASASSPW
                     VLLRARTRSAGVSGWNDETIDAWDPQGAHLGSAHQLRLLRTS"
     gene            10001..11848
                     /locus_tag="F7P10_RS31190"
                     /old_locus_tag="F7P10_31190"
     CDS             10001..11848
                     /NRPS_PKS="Domain: CAL_domain (39-506). E-value: 1.3e-100.
                     Score: 328.9. Matches aSDomain:
                     nrpspksdomains_F7P10_RS31190_CAL_domain.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: FAAL_cd05931"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012711.4"
                     /locus_tag="F7P10_RS31190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31190"
                     /product="fatty acyl-AMP ligase"
                     /protein_id="WP_151014804.1"
                     /sec_met_domain="FAAL_cd05931 (E-value: 4.3e-210, bitscore:
                     699.3, seeds: 56, tool: rule-based-clusters)"
                     /sec_met_domain="AMP-binding (E-value: 2.6e-89, bitscore:
                     298.6, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHFTIPLPEILHRRAREQGDRLAFRFLADGTPEGAVDWTYGDLA
                     RNAAVVAAELAGPRAEGNPRPEGTRVLLAVDPGLHYVASLFGILAAGATAVPSFPPAGR
                     RAAERFLAIVADSAPDTVIASAWQAAEAAELARRLPADRRPRRWIFVDDAFFADAAAGP
                     GELPALSTDPALLQYTSGSTGDPKGIVLTHDNLISNCEVLQRNMGPDPARIGLSWLPPY
                     HDMGLMGTIMLAVHGGWPLVMMSPVHFVQRPVRWLRAVSEYGVTISVAPNFAFDMCVDG
                     VSDDELDGLDLGSLRQLYCGAEPVLKATLDRFRDRFARHGYRESALIPCYGMAEATLFV
                     SGKPDGTMMRTLRLDKAALERGTVQDAPAGAGAVANVVSCGAVAHGHEALIVDARTRRP
                     LPDGTVGEIWVRGPNVAAGYFGRPVPTAETFSASPAGADGGGAPADGGPVADADYLRTG
                     DTGFLRDGELYVTGRLKDVIVIAGRNLYPQDIETSALAAHGELRRAAAFPVRPSGGAES
                     LVVVAELRRAGRRDAAELAAIREAVIAAVTAGHAVRPSGVHLGPPGTVPTTTSGKVRRG
                     AARIAYERGTLKRLAPARSGPDDRAAPAAADEPVGTVSR"
     aSDomain        10118..11518
                     /aSDomain="CAL_domain"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS31190_CAL_domain.1"
                     /evalue="1.30E-100"
                     /label="F7P10_RS31190_CAL_domain.1"
                     /locus_tag="F7P10_RS31190"
                     /protein_end="506"
                     /protein_start="39"
                     /score="328.9"
                     /specificity="Minowa: fatty_acid"
                     /tool="antismash"
                     /translation="TYGDLARNAAVVAAELAGPRAEGNPRPEGTRVLLAVDPGLHYVAS
                     LFGILAAGATAVPSFPPAGRRAAERFLAIVADSAPDTVIASAWQAAEAAELARRLPADR
                     RPRRWIFVDDAFFADAAAGPGELPALSTDPALLQYTSGSTGDPKGIVLTHDNLISNCEV
                     LQRNMGPDPARIGLSWLPPYHDMGLMGTIMLAVHGGWPLVMMSPVHFVQRPVRWLRAVS
                     EYGVTISVAPNFAFDMCVDGVSDDELDGLDLGSLRQLYCGAEPVLKATLDRFRDRFARH
                     GYRESALIPCYGMAEATLFVSGKPDGTMMRTLRLDKAALERGTVQDAPAGAGAVANVVS
                     CGAVAHGHEALIVDARTRRPLPDGTVGEIWVRGPNVAAGYFGRPVPTAETFSASPAGAD
                     GGGAPADGGPVADADYLRTGDTGFLRDGELYVTGRLKDVIVIAGRNLYPQDIETSALAA
                     HGELRRAAA"
     CDS_motif       10520..10579
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS31190_0001"
                     /evalue="7.90E-08"
                     /label="NRPS-A_a3"
                     /locus_tag="F7P10_RS31190"
                     /protein_end="193"
                     /protein_start="173"
                     /score="24.6"
                     /tool="antismash"
                     /translation="ALLQYTSGSTGDPKGIVLTH"
     CDS_motif       11201..11290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS31190_0002"
                     /evalue="3.90E-12"
                     /label="NRPS-A_a6"
                     /locus_tag="F7P10_RS31190"
                     /protein_end="430"
                     /protein_start="400"
                     /score="38.4"
                     /tool="antismash"
                     /translation="PDGTVGEIWVRGPNVAAGYFGRPVPTAETF"
     CDS_motif       11411..11473
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS31190_0003"
                     /evalue="2.90E-03"
                     /label="NRPS-A_a8"
                     /locus_tag="F7P10_RS31190"
                     /protein_end="491"
                     /protein_start="470"
                     /score="10.5"
                     /tool="antismash"
                     /translation="TGRLKDVIVIAGRNLYPQDIE"
     CDS_motif       11639..11671
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS31190_0004"
                     /evalue="9.90E+01"
                     /label="NRPS-A_a3"
                     /locus_tag="F7P10_RS31190"
                     /protein_end="557"
                     /protein_start="546"
                     /score="-3.4"
                     /tool="antismash"
                     /translation="TAGHAVRPSGV"
     gene            11845..12804
                     /locus_tag="F7P10_RS31195"
                     /old_locus_tag="F7P10_31195"
     CDS             11845..12804
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: delta9_cd03505"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012699.4"
                     /locus_tag="F7P10_RS31195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31195"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_151014807.1"
                     /sec_met_domain="delta9_cd03505 (E-value: 1.2e-91,
                     bitscore: 307.5, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVDAVSRGGASAAPPPGSPDGAGTGPDTDAQARRLAYLTVCVPA
                     AGFVAALLWSFRYGFTLVDGLLLGGMYLVTALGVEGGLHRFFSHRAFSARPAVTALWGV
                     AGSMAAQGPIVFWVATHRIHHAFTDTDRDPHSPKPIGGGRLARLRGLWHGHAGWLFTVR
                     RGNWSKHVPDLLGDRTVMRINELYFGWVLLGLAIPAALGGLLTWSVSGAVGGLLWGGLA
                     RIFLLDQVTWGVNSIGHTLGSRPHRTRDNSRNVAALAPLSVGGSWHNNHHARPSLAHNR
                     HTFWQLDVTGAFISLLEALRLVSHVRRPRQGSRAEPRS"
     gene            12809..13753
                     /locus_tag="F7P10_RS31200"
                     /old_locus_tag="F7P10_31200"
     CDS             12809..13753
                     /EC_number="1.14.19.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: delta9_cd03505"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012699.4"
                     /locus_tag="F7P10_RS31200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31200"
                     /product="acyl-CoA desaturase"
                     /protein_id="WP_151014810.1"
                     /sec_met_domain="delta9_cd03505 (E-value: 8.2e-103,
                     bitscore: 344.4, seeds: 90, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATLTAPPDAAIVKLDRGSARIKWITAFAMMTLPGLGTAAAAVLL
                     WQGMFTATDLWLFAGMYFVHMFGITIGFHRYLAHKAFKTSRFFEGVLMIAGSMGGQGPI
                     MYWVTTHRRHHRFSDRDGDPHSPNLAGEGLAAKLRGLWWAHMPWMLSDESSSWRFWAPD
                     VLRDRRLFFYHRTYQLWMVAGLALPALIGFAVEGTAMAALTGFVFGGLARMFVANQAAW
                     CVGSLSHMIGGRPFDNGDRSANNWPVAVFTFGEGLQNNHHAFPGSYRHAVRAWEPDLSG
                     WVLTALGRLRVVRALRQPDAATIAARRARGPRS"
     misc_feature    complement(13849..13862)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: medium, score: 21.38"
                     /tool="antismash"
     gene            13868..14164
                     /locus_tag="F7P10_RS31205"
                     /old_locus_tag="F7P10_31205"
     CDS             13868..14164
                     /GO_function="GO:0000035 - acyl binding [Evidence IEA]"
                     /GO_function="GO:0000036 - acyl carrier activity [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: ACP (21-92). E-value: 2.3e-19. Score:
                     61.5. Matches aSDomain: nrpspksdomains_F7P10_RS31205_ACP.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1047: phosphopantetheine-binding domain-containing
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012759.4"
                     /locus_tag="F7P10_RS31205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31205"
                     /product="acyl carrier protein"
                     /protein_id="WP_151014813.1"
                     /sec_met_domain="PP-binding (E-value: 2e-11, bitscore:
                     43.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFKRTKKARPLDGPLSAESLRAWLIEHLAERVGAAPADIDTGKSF
                     EAYGLDSRVAVQVSGALEKIVERRLSPGLLYEHQTIDDLSAHLASELHLAERA"
     aSDomain        13931..14143
                     /ASF="found active site serine: True"
                     /ASF="non-beta-branching ACP"
                     /aSDomain="ACP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS31205_ACP.1"
                     /evalue="2.30E-19"
                     /label="F7P10_RS31205_ACP.1"
                     /locus_tag="F7P10_RS31205"
                     /protein_end="92"
                     /protein_start="21"
                     /score="61.5"
                     /tool="antismash"
                     /translation="AWLIEHLAERVGAAPADIDTGKSFEAYGLDSRVAVQVSGALEKIV
                     ERRLSPGLLYEHQTIDDLSAHLASEL"
     gene            14187..15302
                     /locus_tag="F7P10_RS31210"
                     /old_locus_tag="F7P10_31210"
     CDS             14187..15302
                     /EC_number="1.14.19.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0016717 - oxidoreductase activity, acting
                     on paired donors, with oxidation of a pair of donors
                     resulting in the reduction of molecular oxygen to two
                     molecules of water [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: delta12_cd03507"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012699.4"
                     /locus_tag="F7P10_RS31210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31210"
                     /product="fatty acid desaturase"
                     /protein_id="WP_151014816.1"
                     /sec_met_domain="delta12_cd03507 (E-value: 3.3e-97,
                     bitscore: 325.0, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFSFPSAPGERFEDFLRKSDQIKDERLAGAIPREYFTPRVGRG
                     LLGFAVSWGLYIGAIVAMAFAPHWLLYLPLLVVAGLGGWGLHCIAHDCGHGSFSRSRKL
                     NVAIGHVSLLPLIYPFHAWRHVHNLHHANTNNLELDTDWKPMPAAMYARMPLRQRLIYH
                     GTRTWAFWGGTINYWRESGFRPSFFPKREMRREVRRSIAFVAVASVLYFPPLIYFTGVK
                     GLLLYFVAPWVATHAWFSATTLMHHSASDVPYLTSEHWTKNAGRLLLTTDYRYPRWLLF
                     LTHNISVHTAHHVAPPVPFYNLPKAQEALKRAYPGMVRERDLKARHLWQIIRRLHFYDT
                     ESGFYTDFGKSQVPPGDGERPREPATVRAAS"
     gene            15299..16168
                     /locus_tag="F7P10_RS31215"
                     /old_locus_tag="F7P10_31215"
     CDS             15299..16168
                     /NRPS_PKS="Domain: Abhydrolase_1 (76-176). E-value:
                     6.8e-12. Score: 37.4. Matches aSDomain:
                     nrpspksdomains_F7P10_RS31215_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF023568.4"
                     /locus_tag="F7P10_RS31215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31215"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_151014819.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 3.2e-08, bitscore:
                     33.4, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 6.4e-07, bitscore: 28.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGPRAPLPVRRLGYAAFGALAPAAAGRRATDAFSTTRALGLRPD
                     DVVPLGARRFRVDGDPDVRGGYVWGEDGPVALLVHGWGIDSSSMQALVPPLRALGYRVA
                     TFDAPGHGVAAGSQATMTQFTRATGAVLDALGDVRAVVAHSLGSIAAAGALAARPGAPV
                     RCLALLAPTCTLTGVLERWARSDLRLRRPVVAEIYRELRRRNGVPVGHWDVVGLGGGLD
                     LPALVLHDPHDDVVPYAEAREVAAGLRGARLEDAPGGHFGILLDPGVRDRVAAFVTRHA
                     STGEEVIR"
     aSDomain        15527..15826
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS31215_Abhydrolase_1.1"
                     /evalue="6.80E-12"
                     /label="F7P10_RS31215_Abhydrolase_1.1"
                     /locus_tag="F7P10_RS31215"
                     /protein_end="176"
                     /protein_start="76"
                     /score="37.4"
                     /tool="antismash"
                     /translation="LLVHGWGIDSSSMQALVPPLRALGYRVATFDAPGHGVAAGSQATM
                     TQFTRATGAVLDALGDVRAVVAHSLGSIAAAGALAARPGAPVRCLALLAPTCTLT"
     CDS_motif       15713..15760
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS31215_0001"
                     /evalue="1.90E-03"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="F7P10_RS31215"
                     /protein_end="154"
                     /protein_start="138"
                     /score="11.2"
                     /tool="antismash"
                     /translation="RAVVAHSLGSIAAAGA"
     gene            16216..16377
                     /locus_tag="F7P10_RS31220"
                     /old_locus_tag="F7P10_31220"
     CDS             16216..16377
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018609957.1"
                     /locus_tag="F7P10_RS31220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31220"
                     /product="rubredoxin"
                     /protein_id="WP_151018404.1"
                     /transl_table=11
                     /translation="MCLVCGFVYREDEGLPEEGIAPGTSWDDIPDDWSCPDCGVSKEDF
                     VMAPMDWE"
     gene            16374..17606
                     /locus_tag="F7P10_RS31225"
                     /old_locus_tag="F7P10_31225"
     CDS             16374..17606
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.4"
                     /locus_tag="F7P10_RS31225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31225"
                     /product="cytochrome P450"
                     /protein_id="WP_151014823.1"
                     /sec_met_domain="p450 (E-value: 4.9e-16, bitscore: 57.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTVQTLADPADVMLRLLAPEGKQNPYPLYEEMRAHGPLVDLNGA
                     HVFATGYAECARALREPAMLSTDAAVQDRKMPGWREHSSWRWLTRNMLFANDPDHERYR
                     RFFGNAFAARSVEAYRPLVERLAAEAVEHVAVLGAGCASVDLVPEFSFRFAADVIGELL
                     GIPADDRRRMRGIIGDITTALDPIGDLSELDRGDGGMDRLAEYTAELVAQRRAAPGTDL
                     TSAFVRARDEGGELTEEELIANLMLLTVAATEAPQDLLSNMVRLALEHPAHGARLRDDP
                     SAAPGFVDETLRYDPAVQALNRVAAHDMDYFGMKIAKGTPVTLLIAAANRDPRRFPDPA
                     VFDPSRSGDQPLTLSGGGHYCLGAALARMSAETVVPMLLRRFPALELAGTPTFRDQLVQ
                     RGHATLPVVTG"
     gene            17674..18570
                     /locus_tag="F7P10_RS31230"
                     /old_locus_tag="F7P10_31230"
     CDS             17674..18570
                     /NRPS_PKS="Domain: Abhydrolase_1 (42-146). E-value:
                     1.3e-28. Score: 92.1. Matches aSDomain:
                     nrpspksdomains_F7P10_RS31230_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     polyyne: PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017570294.1"
                     /locus_tag="F7P10_RS31230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31230"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_218040199.1"
                     /sec_met_domain="PF00561 (E-value: 4.2e-22, bitscore: 78.0,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 4e-17, bitscore:
                     62.5, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGIRDGMSDAELAASLGSGFTSEHAEVNGVRLHYVAGGTGSPLV
                     LLPGWPETWWEYRKVMPALAERHRVIAVDIRGMGGSSRPEAGYEKKAMARDVLELCRHL
                     GHERVAIAGHGIGSMVAFAFAACHPEACDRLVMINTTHIDESYLEFRIMPRPGEPGPYR
                     WWLGFNLVPDFPEAVLEGRYRHMIDYMFGLSLIDPEAIPERDREVYARAYDSADAIRAS
                     KKWFQAYQQDIADFYSYDKITVPVLGLAYGPFYAYMREKLPQQGVDVRVVEIEGSRNYL
                     VEEQPQAVIKALEEFLD"
     aSDomain        17800..18111
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS31230_Abhydrolase_1.1"
                     /evalue="1.30E-28"
                     /label="F7P10_RS31230_Abhydrolase_1.1"
                     /locus_tag="F7P10_RS31230"
                     /protein_end="146"
                     /protein_start="42"
                     /score="92.1"
                     /tool="antismash"
                     /translation="PLVLLPGWPETWWEYRKVMPALAERHRVIAVDIRGMGGSSRPEAG
                     YEKKAMARDVLELCRHLGHERVAIAGHGIGSMVAFAFAACHPEACDRLVMINTTHIDES
                     "
     misc_feature    18679..18691
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 17.22"
                     /tool="antismash"
     misc_feature    18699..18716
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.2"
                     /tool="antismash"
     misc_feature    18701..18716
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     gene            18752..20185
                     /locus_tag="F7P10_RS31235"
                     /old_locus_tag="F7P10_31235"
     CDS             18752..20185
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850666.1"
                     /locus_tag="F7P10_RS31235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31235"
                     /product="MFS transporter"
                     /protein_id="WP_254716117.1"
                     /transl_table=11
                     /translation="MSPSDAQTASSVAPGEPGRGPGGGPGRAAPFGAVFAIVAAGVAMS
                     NLDLFIVNVALPQVGDHFPGASLASLSWILNAYAVVFAALLVPAGGLADRAGAKRAYLL
                     GIAVFTVASVACALAPGVWWLVAARVLQAAGAAALIPSSLGLLLAAAPPERRMAAVRGW
                     TAISGLAAALGPVIGGLLTELDWRWVFLVNVPIGAAAIIAGARLLPGAPARPDARRPDL
                     LGAALLTAGIALLALGVVRSEAWGWASVQVIGVLAAAVVVLAGFVLRSARHPAPVLPLD
                     VLRAPAFSPASLANILFAVAFAAMLLSCVLWCQDVWQWSALRTGLAITPGPLMVPALAI
                     GGAPLARKIGAGPLALAGCAVFAAGIAWWIWRMADGYLLGMLPGMLLTGVGVGLTLPTL
                     IGAAVAALPPQSFSTGSAVVTMARQVGTVVGVAALIAVLGGGEAARSAADFDAGWVLTI
                     AATAAAAAACLFIPRARPR"
     gene            20229..21392
                     /locus_tag="F7P10_RS31240"
                     /old_locus_tag="F7P10_31240"
     CDS             20229..21392
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0003985 - acetyl-CoA C-acetyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006631 - fatty acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1124: acetyl-CoA acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017581720.1"
                     /locus_tag="F7P10_RS31240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31240"
                     /product="thiolase family protein"
                     /protein_id="WP_151014829.1"
                     /transl_table=11
                     /translation="MRDAVIVEAVRTPVGKGKPGGALHGEHSVDLLARTLQSLIERSGI
                     DPATVDDVVGGIVSQVGDQAVNATRSAVLAAGFPESVPATTVDRQCGSSQQAAHFAAQG
                     VISGAYDVAIACGVESMSRVPMGSSVLPGSDPFGPQMAARYPDGLVGQGISAELITSRW
                     KLTRADLDEFAVRSHARASAAWDAGEFDREVAWTGMRDESVRPGTSMEVLSGLKPAYYR
                     DDYAERFPEIGWSITAGNASPVNDGAAALLIMTSETARKLGLRPRARFHSFSVAGADPL
                     LMLTAIIPATEKVLARAGLSIDDIDLFEVNEAFAPVVLAWRHDTGADLEKVNVRGGAIA
                     LGHPLGASGARLMTTLVHALEDRGARYGLQTMCEAGGLANAVIIERL"
     gene            21494..21937
                     /locus_tag="F7P10_RS31245"
                     /old_locus_tag="F7P10_31245"
     CDS             21494..21937
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1167:
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630410.1"
                     /locus_tag="F7P10_RS31245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31245"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_151014832.1"
                     /transl_table=11
                     /translation="MGKDAVPRECSVADALQVVGERWTLLVIRELVYGVRRFDGIVRNT
                     GAARDILTTRLRKLEDAGIVRREPYSSRPVRYEYRLTSKGWELSDVLSVLMKWGDRHLN
                     PDDPPVRWIHTCGERLEPQVVCTHCGRPALEGGHPTGRGARTA"
     gene            complement(21934..23190)
                     /locus_tag="F7P10_RS31250"
                     /old_locus_tag="F7P10_31250"
     CDS             complement(21934..23190)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1020: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.4"
                     /locus_tag="F7P10_RS31250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31250"
                     /product="MFS transporter"
                     /protein_id="WP_151014835.1"
                     /transl_table=11
                     /translation="MGLKDRLNRRDFRLLIVGQAVSSFGDWMGTLALMYFVLEISGSTT
                     AVGGVLVLRLLPSALGAPLAARVVTRWRRRSVMLKSDLIRAGMAVTLPLLPFLWWVYFW
                     AFLIEVVGLIFLPARDAAVPFLIEDDEDEHDTSTLEVANGITMATSYGMIPVGAGAFGL
                     ILWASNQAGWEGHWRYVVVFWLNALTYLVSYVAVRAIPDLGPGPHERRAAEKETETQRG
                     FFAALRLPTVRGVIPAVAVIALGLGALFSLGVVFVRNVLGAGAVGFGALVVLFGVGALI
                     GLLLVHRKGWDLLSQIRTGTVVQGVVIALMGGLASPAWSFIGAVLFGAGATSALVGGIT
                     YLQERLGGGDRNLALTAFHATLRFGLALAALLSGAAADLLDGADATPFGMAPAQFVLTM
                     SGLVVLAGTLLVREPRGAR"
     gene            complement(23169..24350)
                     /locus_tag="F7P10_RS31255"
                     /old_locus_tag="F7P10_31255"
     CDS             complement(23169..24350)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045: glycosyl transferase group 1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630870.1"
                     /locus_tag="F7P10_RS31255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31255"
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="WP_151014838.1"
                     /sec_met_domain="Glycos_transf_1 (E-value: 2.2e-35,
                     bitscore: 120.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDIPRTLVLTGHFPPEPGGVQTFTWELARRLPADRLLVVAPAWRG
                     AAEFDAALPFPVVRRRGYLLFRGLRRLVARHRIEAGWIPAAAPFAMYAPLVRAAGVRRL
                     IGSTHGQELGWFRAVPTRRALHAVAGSFDALTHLCASTLPELEDALGDRTRLVRLAGAV
                     DTDRFRPGLDGAEIRRRHALGSGPVVLSVARLVRRKGHDMLIRAWADVLRRYPDARLVI
                     VGDGPMRRRLTELGDRTAPGAVTVTGPVSDADLPLYYAAADVFALPCRDNRRGLQVEGL
                     GLSTLEASASGLPVIVGRSGGSPESLVDGRTGLLVDASGPDEPALALHRLLADPGRARA
                     MGAAGRRWTRDTWSWDGAAARLAALLRGSAPDAHDAKGRHGPGTEPAWDSRIG"
     gene            complement(24474..25400)
                     /locus_tag="F7P10_RS31260"
                     /old_locus_tag="F7P10_31260"
     CDS             complement(24474..25400)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655691.1"
                     /locus_tag="F7P10_RS31260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31260"
                     /product="hypothetical protein"
                     /protein_id="WP_254716118.1"
                     /transl_table=11
                     /translation="MAVWARSKSRPEQGPERGAPRRRKRWAIITSVFVVLLGVGGYATY
                     QWTRPYLHGTGCEVGAGAGKMSLSLEQGANSATIAAVAFRKELPERAVVIAYATAIQES
                     HLRNLAGGDRDSVGMFQQRPSQGWGTPEQLRDPVVSTSKFFDGLVQVKDYLDKDLHVSA
                     QAVQRSADGELYAQHEPDGELLAAAFTGREPAAARCWFPPDQRTEPRRAEAVREMRRAF
                     GGGLKVDGPRAAGGGAAAPPDPAARWTAVLVPGERMGWAVAAWAVTHAHAYGLTEVRHA
                     GEVWRADAGHDGWTPDPKAPKDRVIIG"
     gene            25445..26278
                     /locus_tag="F7P10_RS31265"
                     /old_locus_tag="F7P10_31265"
     CDS             25445..26278
                     /EC_number="2.3.1.117"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013154904.1"
                     /locus_tag="F7P10_RS31265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31265"
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="WP_151014841.1"
                     /transl_table=11
                     /translation="MTETFTSPISHVIDDLWERRADLTPDDADARAAITAAVDQLDAGE
                     ARVAFIDPATDEVVVDERAKRSILLSFKVLGMVRSQVGDFQYHDRIPLKSRLDGVRVVP
                     GAIARWGAYLAPGVVLMPSFTNFGAYVDSGTMVDTWATVGSCAQIGKNVHLSGGVGIGG
                     VLEPPNAKPVIVEDEAMIGSRSMIVEGARVGKGAVVGSGTNLSASMPVIDVETGEEISR
                     GRIPDWCVAVGGTRTKEFKGGTYGLPAVLILKRLEEGQRHDKAELNDILRDHGLG"
     gene            complement(26338..27057)
                     /locus_tag="F7P10_RS31270"
                     /old_locus_tag="F7P10_31270"
     CDS             complement(26338..27057)
                     /NRPS_PKS="Domain: ACPS (119-178). E-value: 2.7e-10. Score:
                     32.1. Matches aSDomain:
                     nrpspksdomains_F7P10_RS31270_ACPS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1012: 4'-phosphopantetheinyl transferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017596604.1"
                     /locus_tag="F7P10_RS31270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31270"
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="WP_254716119.1"
                     /transl_table=11
                     /translation="MSDKRTRHRIIVVETPIEVQWSAPADEPHMRDLLHAAERTRYDRF
                     LRPEDKARFVTGRFLARTALAARTGLSPDAIAFTTECPHCGADHGKPRLPGHDVDFSLS
                     HSGDRVVLAVAEGVRIGVDVERESDRDIDRLAEMVLAAPEREDFAALPLEERRRAFHVY
                     WSRKEAVLKATGHGLAAPMTDLRLSAPGTAPEVLSWEGDAAVAPVRLADLTPGAGYAAA
                     LAVLTAAPLKVTENPGP"
     aSDomain        complement(26524..26700)
                     /aSDomain="ACPS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS31270_ACPS.1"
                     /evalue="2.70E-10"
                     /label="F7P10_RS31270_ACPS.1"
                     /locus_tag="F7P10_RS31270"
                     /protein_end="178"
                     /protein_start="119"
                     /score="32.1"
                     /tool="antismash"
                     /translation="IGVDVERESDRDIDRLAEMVLAAPEREDFAALPLEERRRAFHVYW
                     SRKEAVLKATGHGL"
     misc_feature    complement(27009..27029)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.8"
                     /tool="antismash"
     gene            27056..28114
                     /gene="dapE"
                     /locus_tag="F7P10_RS31275"
                     /old_locus_tag="F7P10_31275"
     CDS             27056..28114
                     /EC_number="3.5.1.18"
                     /GO_function="GO:0009014 - succinyl-diaminopimelate
                     desuccinylase activity [Evidence IEA]"
                     /GO_process="GO:0009089 - lysine biosynthetic process via
                     diaminopimelate [Evidence IEA]"
                     /codon_start=1
                     /gene="dapE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1247: acetylornithine deacetylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851539.1"
                     /locus_tag="F7P10_RS31275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_31275"
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="WP_151014844.1"
                     /transl_table=11
                     /translation="MRLDLFSDVTDLTAAIVDIESVSGAEGPLADAVEEALRALPHLAV
                     ERTGHNVVARTELGHAERVVLAGHLDTVPLNGNLPSRVEGDRLYGCGTTDMKSGVAVAL
                     RLAATVPEPTRDVTFVFYECEEIEAERNGLRRLAAERPELLAGDFAVLMEPTGALIEGG
                     CQGTIRVEVTATGERAHSARAWMGSNAIHSAGRILDVLRAYEPTRPVVDGLEYHEGLNA
                     VFVRGGVAGNVIPDECVVTVNYRFAPDKSLDEAERYLRRIFDGFAVKVTDASPAARPGL
                     THPAADAFVRAAGAEVRAKLGWTDVARFAELGVPAVNYGPGEPTLAHTKDEYVEIPLIG
                     DCEHRMRAWLTA"
ORIGIN
        1 tcgaagacat gtcggacgac gctgacgacg cgtccaccac cctcgatcgt ctccggtgcc
       61 accccctctc ccagaatttc caggagatgg tccagttgtc cgggtgccgg tctgcctcgc
      121 cgacctcggc cttcgttcgt tccgcctgct gggaggatac gttgagccgc cgtacttccc
      181 ggtcgcgcaa ccggtcgtca caggccatcg ttcgcaggag gtatatctcg aaatcgaggg
      241 cgctcaaact atgtctctcc gagaaaccgc cgaggatggg ggaaagcgcg cgcggcgtct
      301 cgcggcgccc cggcgcgcga gacctcggcg gcgagccggg ggagttccga cgaggatccc
      361 cccggcgcac ctcggacggt gcgcaggggg cgcctcgggt gcgtccggga ggtgcggttc
      421 cgaaccacgg ggccggtacg acctcggggg cggccgatca ccagcaggcg tacggcgctc
      481 cgtagcggag caggaccgga gccgtctggg tgaccgtacc gtcactcgcc caaacttcgg
      541 ccacgtagtc gcccgccggg gcgggggcga acgagacccc tacgaagccg ttgatggtgt
      601 tctcgtcgtt gcttcccggc gggagcacgg acccgccgag gtcggacgaa ccgggcggca
      661 ggttccggat cccggtcgtg atcggggtcg tccaggtccc gctcacgggc gcgaacacgt
      721 aggtgccgtc ccagccgccg gtgctgacgc agaccttctg cccgatgtcc tgcagggtcc
      781 aggtcgggct ctccgcgctt gccggggcgg cgccgatcag ggacatcgcc agcacggcca
      841 gcattccgac cacgattctc gcgctgtttc gggccgactt catcggggcg cctcctgata
      901 ttcctcggga tcgatcaccc actccgggag cattttgcgt cattgtttcg tcatagaaca
      961 gagcgttcgc ctgttgcatg tttcggtgtt tcgtgttcgc cctgcggagg aacggtttcg
     1021 gcggggcgca gatgctcgcg cgttcgctcg tggcgccgcc gtacgcgcgg acgggtgggc
     1081 gggccggcca cgcgcgcccg tggccgggtc ccgggcgtcg tcagaagtcc gcgccgatga
     1141 tgctgtcgat gttgcgttcg gcgagggcgg tgatggtgac gaacgggttg acgctggtgt
     1201 tgccggggat gagcgcgccg tcgatgacgt agaggccggg gtggccgtgg aggcggccgt
     1261 ggttgtcggt ggccttgttg aggacggcgc cgccgagggg gtggtaggtg aggtggtcgc
     1321 cccagatctt gtagacgccg aagaggtcgg tccggtagat cgtcccctcc ttgcggttga
     1381 tcttgtcgaa gatcgtcttc gcgcggtcga tactcgcctg tttccaggcc gtctgccagt
     1441 tcaggtcgac cctggacgcc gaggcgttcc aggagaactg ggcgcggtgc ggggtgttgg
     1501 tgatcgagag gtagaacgag gcgaaggtct cgatcccggt gggcaggggc gcgacctcgg
     1561 cgaacgctcc gcccgcgtcc cagttgtcga tgccgaccgt ggggatggac gactggagcg
     1621 agccggtcgc gtcccacatg tggttggcgc ggccgcacat gatgttgccg ttgtcgcccc
     1681 agcccttgcc gatctcgccg ttgaggttgg gcagcgcgcc ggtcgccttg agtttcacga
     1741 ggagcttgct ggtgccgacg cttccggcgg cgaagaagac ctttccggcg gtcacggtct
     1801 tggtggccgt cacgttgccg ccggtgtcga gctgctcgat ggtgaccgtg tagccgccgg
     1861 acgccggggt caccgaggtg acgcggtgca gcggggagac cgacacccgg ccggtggcgg
     1921 cggcctgggc gaggtaggtc tgctggagcg acttcttacc ggcgttgttg ccgtagagga
     1981 tctccgcgtc gagggccgac cgggggacgt tgcccgcggc ttcctgcttc atgtagttga
     2041 agtcgtagac gttggggacg tagacgaagt cgaagtccga gcgttcggcg tgcttgcggc
     2101 cgacgcgcgc gtacttgtag cagtcggtgg tgtcgaacca ggcccggtcg atctggttga
     2161 ccccgagccc ggcattcgcg cgggggtagt agacgtcgta catctcgtcg gcgtccacgg
     2221 acgggaggat ggcgccgaag cgctcgcgct ggggggtgac ggccatgccg ccgttgacga
     2281 gcgagccgcc gccgacgccg cgtccctggt agacggtgat gccgccgaac tcctcggcgt
     2341 ccaggatccc ggtgtagcgg gggacgttct tgtcgagcgg gaaaccgagg aagttgctga
     2401 ggggctgctt ggtgcgggtg cggagccagt aggagcggta gtcgggggac cgggtgttgg
     2461 cgaagatctt gccgtcgtcg ccgggggtgt tccacgacat gcccatctcg accatgtgga
     2521 cgtcgacgcc ggcctgggcg aggcgcagcg cggcgacgga gccgccgtaa ccggacccga
     2581 tgacgaggac cggaacgcgg gcgccgttac cgatcgaggt ggtcgcggcg gcggcgcttc
     2641 ccgtccggga cagcaggccg aggccgatga tggaaccggt tccagctagg aatccgcgcc
     2701 gcgagacacc ggtagaaccg cgttcgggca ggggtgtact gcgcatgtga gctccctcac
     2761 aaccggggtg ggttgaaaca ggttctaccc cgagggcccg ggaaaggcca tggcatacgc
     2821 gagagtaact tgcattcgaa tactgacctg tagtaaccgg ttacggtcag tgaaccaaat
     2881 gcttgcttgg caagggggtc cggccctgtt agcctccggc gtatgatctc cacggtcgtc
     2941 tggggcaccg gtaacgttgg tcggctggcc ctccgggccg tcgaggccca tcccgcgctg
     3001 gaactctcgg gcgtgatcgt ccacgacccc ggcaaggtcg gacgggacgc cggcgagctg
     3061 ggcgggctcg atcggacgct cggcgtcgcg gcgaccgacg acgccggcgc ggtgctggcc
     3121 gccgggccgg gggccgtcgt ctacgcggcg tccggcgaca tccggccgga cgaggcgctc
     3181 gccgacatcc tgcgggcgat ccgggccggg gcggtcgtcg tcagcccggc actgtacgcg
     3241 ctctacgacc agcgcaacgc cccggcggag atgcgggagg cggtgctggc cgcgatcgag
     3301 gagggcggcg ggtccctctt cgtgtccggc gtcgacccgg gctggggcaa cgacgtactg
     3361 ccgctgctgg tcagcgggct ggggcacacc gtggacgtcg tccgctgcca ggagatcttc
     3421 gactactcca cctacgacca gcccgactcg gtgcggtacc tcgtcgggat ggggcagccg
     3481 atggactacg agccgccgat gctcgcgccg tccgtcccga ccatggtgtg gggcgggcag
     3541 gtgcggctga tcgcgcgggg gctcggcgtc gagctggacg aggtccgcga gacgctggac
     3601 cggcgcccgc tggacgcgac cgtgacgacg gcgtcgatgg gcgacttcga gaagggcacg
     3661 cagggcgcgg tgcggttcga ggtgcaggga atcgtggggg gcgagccccg catcgtggtc
     3721 gagcacgtca cccgcatcca cccgtcctgc gcccccgact ggcccgtgcc gccggacggc
     3781 gacggcgcgc accgcgtgat catcgagggc gatccgcgca tcgaggtcac ggtcgaggcc
     3841 accgacgccg ccgggaaccg ggccgcgggc ggcaacggca ccgcggtcgg acggctcgtc
     3901 ggtgcgatcg actggctcgt cgaggccgaa ccgggactct acgacgcgct cgacgtcccc
     3961 atccgtcccg cgaccggcaa gctcggaagg acggcgcgat gaacatcgac atccccggcg
     4021 gcaaggaccc gatcgggtac gtgtgggggg agatggtgcc gggcatcggc cccgccgccg
     4081 cgaacttctc catggcggtg tacgcccaca ccacgctggg cctccgcgag ttcgaggccg
     4141 cacggctgcg gatcgcgcag atcaacggtt gcgtcttctg cctcgactgg cgcaccgaac
     4201 gggacggcga gaaggtcgag gacggcttcc tcgacgccgt gaccgagtgg cgcaccacca
     4261 ccgcgttcga cgaccggacg cgcctggccg ccgagtacgc ggagcggtac gccgtcgacc
     4321 accacggcct cgacggcgag ttctgggacc ggatgaccgc gcactacagc caggtcgaga
     4381 tcgtggagct gagcatgtgc ctcggctcct ggctcgcctt cggccgcctg aaccacgtcc
     4441 tgggcctcga cgccatgtgc atgctcccca acaagccctg acccgccccg gccgtccgct
     4501 ggctcacgaa ccgggcggcg gcctccggcc ggccccggcg tccgcggggc cgtccgggcc
     4561 ggtgccttgg tcgccgccgg ggtggtggag cgcggccgcg gcgcggacga gcgccgcgac
     4621 ctccctggag cggctggccg acggccacgc gatcaccgtg gtgacctccg gtgcgtcggc
     4681 gacgggcacc gcgacgtgtt cgggccactg ccaggcgcgg ctggaggcgg ggatgacgag
     4741 cagcgtccgg ccgagcgcga cgagctgggc gagctgcgac tgcgtgcgca cctccggtcc
     4801 gggcccgtcc gggtaggtgc cgtcgagccg gggccagcgg gcgatcggca ggtccgggac
     4861 gtgctggacg tccgccagcg tgagccggtc gcgggcggcg agcggatgcg cggcggggag
     4921 gatcgcgacc tggccctcga cgcagaggtc ctcggtgtcg aacccggcga ggtcgtcgta
     4981 ggggcggtgc atgagcgcga cgtcggcccg cccgtcgcgg agcagccccg cctgctcgcc
     5041 gacctcgcac agcaggacct cgacgggcgc cgcgccgggg tcgctcgcga gggcgccgag
     5101 gagccgctgg agcagctcgt gggacgcccc ggccttcgtc gcgagcacca gcggccgctc
     5161 cggatccccg gcgcgccgcg tccgccgcgc ggcggcggcg accgcgtcga gggccgtccc
     5221 ggcctcgcgg agcagcaccc ggccggcgtc ggtgagcgcc accccgcggc ggtcccggtc
     5281 gaggagccgg acgccgagcc gccgctccag ccggccgatc gcgcgggaga gcggcggctg
     5341 cgcgatcccg agccggacgg cggcgcgccc gaagtgcagc tcctcggcga cggcgacgaa
     5401 gtagcggagc tcgcgggtct cgagatcgtc cacgcgtgca ggctaccggc cgatacccgg
     5461 cgggtatcac agccgaccgg agcggtgttg gacggcggcc gcggtgcccg cggagcatgg
     5521 agcgcgtgaa cgagacgaag accgcgctgg tgaccggcgc gaacaagggg atcggtttcg
     5581 ccatcgcccg ggggctcggg gcgatcggct tcacgctcgc ggtgggagcc cgcgacgagg
     5641 gaaggcgcga ggaggccgtc gggaagctgc gcgccggggg cgccgacgcg ttcggggtgg
     5701 ccctcgacgt cacctccgac gcgagcgtcg ccggagcggc ggaggcgatc gagcggacgg
     5761 cgggacggct cgacgtgctc gtcaacaacg cgggcatcgc cggccggacg gacggcggcg
     5821 cgcaggaccc ggcgacgctc gacctcgatg tcctccgcac cgtcctggac acgaacgtgt
     5881 tcggtgtcgt gcgggtgacg aacgcgatgc tgccgctgct ccgccgcgcg gactccccgc
     5941 gcatcgtcaa catgtcgagc aacatgggtt cgctggagct ccggacgggc ccggtcctgg
     6001 ccgcgtacgc gccgtcgaag tcgctgctca acagcatcac ggtgcagtac gcccggggct
     6061 tcgagggcac gaacgtcatc gtcaacgcgg cctgccccgg ttacgtggcg accgacttca
     6121 ccggcttcgc cgcgccgcgg acgcccgagc agggcgccgc gatcgcgatc cgcctcgcca
     6181 ccctgccgga cgacggtccg cgcggcggtt tcttcgacga cgcggggacc gtcccctggt
     6241 gaggcgtcct acccggcgtc cgggagtttg tccgggttgg tgacggtgta gatgccggtg
     6301 atgtggtcgc cgtcgaggtc gaggaccatg acggcgaacg gggcgtcgcc ggcgaacagg
     6361 acggcggacg ggtcgccgtt gacggtgcgg tagtcgatgt cgaggtcgac ctcccgggcc
     6421 tggcgggggc ggtggcggcg agggtgcggg cgacgcggtc gcggccgtgg atcgggcgga
     6481 gcgggctgcc gggggcgccg ccgccgtcca tccagagggt gacgtccggg gcgaggatct
     6541 ccaggagcgt gccgatgtcg ccgccgagcg cggcgcgcag gaagcgctcg gtggcctgcc
     6601 gctggacgcg cgggtccgcg gggaaccggg ggcggcgggc gtggacgtgc gcgcgggcgc
     6661 gccgggcgag ctgccggacg gcggccgggc tgcggtccag gatcgcggcg atctcggtgt
     6721 gcgggtagcc gaacacctcg tacaggacga acacggcccg ttcgagcggc gtgagggtct
     6781 ccaggacgac gaggagggcc atcgagacgg cctcggtgcg ttcggcggac tcgtcggcgc
     6841 cggcgacgag ggggtcgggc agccaggggc cgaggtaggt ctcgcggcgg cggctgatcg
     6901 cggcctgccg ggcgagtgcg gcgttgacgg cgacgcggac gaggtaggcg cgggggttcg
     6961 tcacctcggg acggtcgcgg gacgaccacg cgagccacgc gtcctgcagg acgtcctcgg
     7021 tgtcggcgac gctgccgagc aggttgtaga cgaccgagaa cagcagctcg cggtggtcgg
     7081 tgaaggtgcg cgtggcggtg tccgcggcgg cgccgtggcc gccggcgtcc cggccggtgg
     7141 tgtcgggtgc gtccatgtcc atgagagggg tctcggtgcc acgagtgtga catgccgccg
     7201 cggtcgggac gtgccggggg cgttatccgt tcgtgaagtc gaagatcctt ttcgggtgtc
     7261 ggcactggtg cggaagcgga tgcggggccg gttccgcatc ggtgaaatcg ccggtctcgc
     7321 gcactgatga cggtatgtga ttgatcattg cgcgcacaca gcgggtgagt ggacatttgt
     7381 ttgaaatatt ggctcgccgg agtggatcgg gtgctgtttt gaccgatcca ggacggtgag
     7441 gacggacgcc gcccgtgctc acggcgtggt cgccggtgcg aggcacgtac cggttgacgt
     7501 ggggttatgt ggtcggcggg tggcccgggg gcgtcagggc gcgcaaagtt tccgaccata
     7561 acaataaccg ggcccgcgcg tcgtcactgt cggtgattaa gcggataatg tctagagggc
     7621 gcggattttg tgaccgagac tggcggggtc gccccccgcc ccccgggacc cgcagtcccg
     7681 gtacgcggcg gcattccgtc gatcttcggg aggaacgccg tgcccgacgg ccagcttgtt
     7741 cgcacacgcg tgatcgatga ataccccgag aacggcctgg acgtccggga gcgctaccag
     7801 aaggcgatgc gcctgcgcgt gcaccacctg acggggcgcg tcctggacat gctcaagcag
     7861 gccgagcacg cctaccgcag cagcggaacg atcccgcagc aggagccgcc gcagtggatc
     7921 gcgcggtcca tcgaccgggc cctggacgcg gtgacgctgc cgcccgcgga gatggccgcg
     7981 acccttgaca tgcccgaccg gacgggcacg cggcggggcc ggcagggcgt cccggaacgc
     8041 gcgctgctgc gggcctacca cctcggcggc cgggagctgt cggtggcgtc ggcgcagtgg
     8101 gcgatggagg agggtgtcga ccaccgggac gtcgccccgc tgatcgacgc gatctggcgg
     8161 gtcaccgagg agcactcgtc ggccgcggtc gcggccctgc gcggcgcgcg cgaggagatc
     8221 gtggagccga gccgcgccgg gcacctgctg gacgcgctgc tgaacgggga cgaggagagc
     8281 cgcacggtcg cggcggtcgc ccggtcgttc gccgtcccgg agaccggacg gtacgcggtg
     8341 gtggtgcggc atccggcgca cgggggcgtc cgggaggagg acctcgtgcc gttcgcccgc
     8401 ggcacgcggc tggtgtggcg gcggcacggc gtgacggcgg tcggcgtcgc ggtgctcggc
     8461 acggcggcgg cgacgagcct ggcgggcgcg ctgcccgccg ccggcgggta ccggacgggg
     8521 gtcagcggcg cgatggaggg gctggcgtcg ctgggccgcg cacggcaggg cgcggaggcc
     8581 gcggcgcgga cgctgcgcgg gccggggctg gcgttcctgg aggagcggtt cccggcggcg
     8641 atgctgcacg ccgaccccgg gctggcgcgg cagttccagg cgcaggtcct ggcgccggtg
     8701 ctggcgctgg acgcgggccg gcgggacgcg ctgctggaga cgctggaggc gtggctgcgc
     8761 gcgggcgggt cggcgggccg ggtggccgac gacctgttct gccaccggaa cacggtgcag
     8821 aaccgcctgc ggcggctgga ggagctgacg gggcggtcgc tgtcggcacc cacggacgtg
     8881 atcgatctcg ggctggcggt ccaggcgttc cggcagttcg gggacgagcc gccgggccgc
     8941 gccgggtagc gggcggcgcc gcggcgggat ctggtggcgg gaggcccgcc ccccgtagag
     9001 tgagtttgct gatccaactc actttggagg tgggccgatg acggttcctg cgatcgtcgc
     9061 gcccggcgcg ctgctgcgtt ccccggtcga ggggccgctg gtcccggacg gacggctgtt
     9121 cggcttcggc ggcctgcacg gcggcctggc gctggcgctg ctgaccgcgg cgatgcagcg
     9181 ccgggccgcg ccggacgcgg tgctgcgcgg ggcgtccgcg cggctgcacc gggcgctcgc
     9241 cggggagttc accgtcacga cgcgggtgct gcggcccggc ggcgtcacga ccgtcgcggc
     9301 cgaggcggct tcggccgagg gcgtgcacgt cgacgcgtcg gcgatcttcg ccgggccgta
     9361 cgcggccggc ggcccggtgc tggcgccgcc cgcgcccgcc gcgccgccgc cgggggactg
     9421 cgagatcttc cgcatcccgc cggagttcgt gccgatctcg gagttctggg agatccgccc
     9481 ggtcggcgcc aaccgcccgt acgcgggatg cgcggagccg gagctgacgg cgtgggtccg
     9541 gctgctggag gacgacgagg cccccgacgt ccaccgcctc atgctgctca tggacgcgct
     9601 cgcccccgcc tacgcggccg tcctggggga cctgcggctg gtcccgacga tggagatgtc
     9661 ggtccggacg ggcgacggcc tggcgtccgc gtcgtcgccc tgggtgctgc tgcgcgcgcg
     9721 cacgcggagc gccggggtga gcggatggaa cgacgagacc atcgacgcct gggacccgca
     9781 gggcgcccat ctgggctcgg cgcaccagtt gcggctgctg cgcacgtcct gacggccggg
     9841 acggccgcgg gccggggttg tgcagccgcg acactttccc ccggtccgct tggtcgccgc
     9901 acacagatct gctcgccgcc gcttccccga cattgacctc cggctcggcg ccgtggaaat
     9961 ctcctgctcg ttgtcgtcca tctctcgaca gggacggtaa atggagcatt tcacgattcc
    10021 attgcccgaa atactgcatc gacgagcacg agaacagggt gaccggctcg cgttccggtt
    10081 cctcgcggac gggacaccgg agggggcggt cgactggacc tacggtgacc tggcacggaa
    10141 cgcggccgtg gtggccgccg agctggcggg cccgcgcgcc gaggggaacc cgcggcccga
    10201 gggaacgcgc gtcctgctcg ccgtggaccc cggcttgcac tacgtggcct cgcttttcgg
    10261 catcctcgcc gccggcgcga ccgccgtccc gtccttcccg cccgccggcc ggcgggccgc
    10321 ggaacggttc ctggcgatcg tcgccgacag cgcgccggac acggtgatcg cgtccgcgtg
    10381 gcaggccgcc gaggcggccg agctggcgcg ccggctcccc gccgaccgcc gcccgcggcg
    10441 ctggatattc gtggacgacg catttttcgc ggacgccgcg gcgggccccg gggaattgcc
    10501 cgcgctatcc accgaccccg ccctgctgca gtacacctcg ggatccaccg gtgatcccaa
    10561 gggaattgtc ctcacccatg acaatctgat cagcaattgc gaggtgctgc agcggaacat
    10621 gggcccggac ccggcccgga tcgggctgtc gtggctgccg ccgtaccacg acatggggct
    10681 gatggggacc atcatgctcg cggtgcacgg cgggtggccg ctggtcatga tgtcgcccgt
    10741 ccacttcgtg cagcggcccg tccggtggct gcgcgcggtg agcgagtacg gcgtcacgat
    10801 ctccgtcgcc ccgaacttcg cgttcgacat gtgcgtcgac ggcgtctccg acgacgagct
    10861 cgacggcctg gacctgggca gcctccggca gctctactgc ggtgccgaac cggtcctgaa
    10921 ggcgaccctc gaccggttcc gcgaccggtt cgcccggcac ggctaccggg agtccgcgct
    10981 gatcccctgc tacgggatgg cggaggcgac gctgttcgtc tccggcaagc ccgacggcac
    11041 gatgatgcgc accctccgcc tcgacaaggc ggccctggaa cgcggcaccg tgcaggacgc
    11101 cccggccgga gcgggagccg tcgcgaacgt ggtgagctgc ggggccgtcg cgcacgggca
    11161 cgaggcgctg atcgtcgacg cgcgcacccg ccggcccctg ccggacggca cggtcgggga
    11221 gatctgggtg cgcgggccca acgtcgcggc cggctacttc gggcggccgg tgccgaccgc
    11281 cgagacgttc tcggcgtccc cggccggagc ggacggcggc ggcgcgcccg cggacggcgg
    11341 cccggtggcg gacgccgact acctgcgcac gggcgacacc gggttcctgc gcgacgggga
    11401 gctctacgtg accggccgcc tcaaggacgt gatcgtcatc gcgggccgca acctgtaccc
    11461 gcaggacatc gagacgtccg cgctggcggc gcacggcgag ctgcgccgcg ccgccgcgtt
    11521 cccggtgcgc ccgtccggcg gcgccgagtc gctggtggtc gtcgccgagc tgcgccgtgc
    11581 gggacgccgg gacgcggcgg agctcgcggc gatccgggag gcggtgatcg ccgcggtgac
    11641 cgccgggcac gcggtgcggc cgtcgggcgt ccacctcggc ccgcccggca cggtgccgac
    11701 gaccacgagc gggaaggtgc ggcgcggcgc ggcccgcatc gcctacgagc gcggcaccct
    11761 caagcggctc gcgcccgccc ggtccggccc ggacgaccgg gcggcgcccg cggcggcgga
    11821 cgagccggtc gggacggtgt cgcgatgacc gtggacgccg tctcgcgcgg gggcgcctcc
    11881 gccgccccgc ccccgggatc gccggacggg gcgggcacgg gccccgacac cgacgcccag
    11941 gcgcgccgcc tcgcctacct cacggtgtgc gtgcccgcgg ccgggttcgt ggccgcgctg
    12001 ctgtggtcgt tccgctacgg gttcacgctc gtggacggcc tgctgctcgg cggcatgtac
    12061 ctggtgacgg cgctgggcgt ggagggcggc ctgcaccggt tcttctcgca ccgggcgttc
    12121 agcgcccgtc ccgccgtgac cgcgctgtgg ggcgtggcgg gaagcatggc ggcgcagggg
    12181 cccatcgtgt tctgggtggc gacgcaccgc atccaccacg ccttcaccga caccgaccgc
    12241 gacccccatt ccccgaagcc gatcggcggc gggcgcctcg cgcggctgcg cgggctgtgg
    12301 cacgggcacg ccggctggct gttcaccgtc cggcgcggga actggagcaa gcacgtcccc
    12361 gacctgctcg gcgaccgcac ggtcatgcgg atcaacgagc tgtacttcgg ctgggtgctg
    12421 ctcgggctgg cgatcccggc cgcgctcggc ggcctgctga cctggagcgt cagcggggcc
    12481 gtcggcgggc tgctgtgggg cgggctcgcc cggatcttcc tgctcgacca ggtcacctgg
    12541 ggcgtgaaca gcatcggcca cacgctgggg agccgcccgc accggacgcg cgacaacagc
    12601 cgcaacgtcg ccgcgctggc acccctgtcg gtcggcgggt cgtggcacaa caaccatcac
    12661 gcccggccgt cgctggcgca caaccggcac acgttctggc agctcgacgt caccggggcg
    12721 ttcatcagcc tgctggaggc cctgcgcctg gtctcccacg tccgccggcc ccggcagggc
    12781 agccgggccg aaccgaggag ctagttccat ggcaaccttg accgcgccgc cggatgcggc
    12841 catcgtcaag ctcgaccgag gcagcgcccg gatcaagtgg atcacggcgt tcgccatgat
    12901 gacgctgccc ggcctcggga cggccgccgc cgccgtcctg ctgtggcagg gcatgttcac
    12961 cgcgacggac ctgtggctgt tcgccgggat gtacttcgtg cacatgttcg gcatcacgat
    13021 cgggttccac cggtacctcg cgcacaaggc gttcaagacg tcccggttct tcgagggcgt
    13081 gctgatgatc gccgggtcga tgggcggcca ggggcccatc atgtactggg tcaccacgca
    13141 ccgccgccac caccgtttca gcgaccggga cggcgatccc cactcgccga acctggcggg
    13201 ggaggggctc gcggccaagc tgcggggcct gtggtgggcg cacatgccgt ggatgctcag
    13261 cgacgagagt tcgagctggc ggttctgggc acccgacgtc ctgcgggacc gccggctgtt
    13321 cttctaccac cggacctacc agctgtggat ggtcgccggg ctggccctgc ccgccctgat
    13381 cggcttcgcc gtcgagggga cggccatggc cgcgctgacc gggttcgtct tcggcggcct
    13441 cgcccggatg ttcgtggcga accaggcggc ctggtgcgtc gggtccctca gccacatgat
    13501 cggcggacgc ccgttcgaca acggcgaccg cagcgccaac aactggcccg tcgccgtctt
    13561 caccttcggc gagggactgc aaaacaacca ccacgccttc cccggttcct accggcacgc
    13621 cgtccgggcc tgggagcccg acctcagcgg ctgggtgctg acggccctcg gccggctccg
    13681 ggtcgtccgg gccttgcggc agccggacgc cgccacgatc gccgcccgcc gcgcccgcgg
    13741 cccccgctcc tgaccccgcc cgatcccgag cccgcacgtt cctgagcccg cacgttcctg
    13801 aacaccgcgt atgtcctcaa gtccctgagc ccgcatgtcc agcacgtctc acggagagtg
    13861 atcgaacatg ttcaagcgca ccaagaaggc gcggccgctc gacggcccgc tgagcgccga
    13921 gtcgctccgc gcctggctca tcgagcacct ggcggaacgc gtcggcgcgg cgcccgccga
    13981 catcgacacc ggcaagtcgt tcgaggccta cgggctggac tcccgcgtgg cggtccaggt
    14041 gtccggcgcg ctggagaaga tcgtcgagcg gcggctgtcc ccgggcctgc tctacgagca
    14101 ccagaccatc gacgacctga gcgcccacct cgccagcgag ctgcacctgg ccgagcgggc
    14161 ctgagcgcgg aaggagaccg gcgaccatgt ccgccttcag tttcccgtcc gcccccggag
    14221 agcggttcga ggatttcctg cgcaagtccg accagatcaa ggacgagcgg ctcgcggggg
    14281 ccatcccgcg cgagtacttc accccgcgcg tggggcgcgg cctgctcggc ttcgccgtca
    14341 gctggggcct gtacatcggc gcgatcgtcg cgatggcgtt cgccccgcac tggctgctgt
    14401 acctcccgct gctcgtcgtc gcgggcctcg gcggctgggg gctgcactgc atcgcgcacg
    14461 actgcgggca cgggtcgttc tcgcggtccc gcaaactcaa cgtcgcgatc gggcacgtct
    14521 ccctgctgcc gctgatctac ccgttccacg cgtggcggca cgtgcacaac ctgcaccacg
    14581 ccaacaccaa caacctcgag ctggacaccg actggaagcc gatgccggcc gcgatgtacg
    14641 cgcggatgcc gctgcggcag aggctgatct accacggcac ccgaacctgg gcgttctggg
    14701 gcgggacgat caactactgg cgggagtcgg ggttccgtcc gtcgttcttc ccgaagcggg
    14761 agatgcggcg cgaggtgcgg cgctcgatcg cgttcgtggc cgtcgcgtcc gtcctttact
    14821 tcccgccgct gatctacttc accggggtca agggcctcct gctgtacttc gtcgcgccgt
    14881 gggtggccac ccacgcgtgg ttcagcgcga cgacgctgat gcaccacagc gcgtccgacg
    14941 tcccctacct gacctccgag cactggacga agaacgcggg acggctgctg ctgacgacgg
    15001 actaccgcta cccgcgctgg ctgctgttcc tcacgcacaa catctccgtg cacaccgcgc
    15061 accacgtcgc ccctcccgtc cccttctaca acctgccgaa ggcgcaggag gcgctgaagc
    15121 gcgcgtatcc gggcatggtg cgcgagcggg acctgaaggc gcggcacctg tggcagatca
    15181 tccgccgcct gcacttctac gacaccgagt cgggcttcta caccgacttc ggcaagtcgc
    15241 aggtcccgcc cggggacggg gagcgcccgc gggagcccgc gaccgtccgg gccgcctcgt
    15301 gacgggcccg cgcgcaccgc tgcccgtccg gcgcctcggc tacgcggcgt tcggcgcgct
    15361 cgccccggcg gcggcggggc ggcgcgcgac cgacgccttc agcaccacgc gggcgctcgg
    15421 gctccgtccc gacgacgtcg tcccgctggg cgcccggcgc ttccgggtgg acggcgaccc
    15481 ggacgtccgc ggcggctacg tgtggggcga ggacggcccg gtcgcgctcc tcgtgcacgg
    15541 ctggggcatc gacagcagca gcatgcaggc gctcgtcccg ccgctgcggg cgctcgggta
    15601 ccgggtcgcg acgttcgacg cgcccgggca cggcgtcgcc gccggctcgc aggccacgat
    15661 gacgcagttc acccgggcga ccggggcggt gctggacgcg ctcggcgacg tccgcgcggt
    15721 cgtggcgcac tcgctcggct ccatcgccgc ggcgggggcg ctcgccgccc ggcccggcgc
    15781 gcccgtccgc tgcctggcgc tgctcgcccc gacctgcacg ctgaccggcg tcctggagcg
    15841 ctgggcccgg tcggacctgc ggctgcggcg gccggtcgtg gcggagatct accgggagct
    15901 gcggcggcgc aacggcgtgc ccgtcggcca ctgggacgtc gtcggcctcg gcggcgggct
    15961 cgacctgccc gcgctggtgc tgcacgaccc gcacgacgac gtcgtcccgt acgccgaggc
    16021 gagggaggtc gcggcgggcc tgcgcggcgc ccggctggag gacgcgccgg gcgggcactt
    16081 cgggatcctg ctcgaccccg gcgtgcggga ccgggtcgcg gcgttcgtca cccggcacgc
    16141 gagcaccggt gaggaggtga tccggtgagg agcggcgaca cgaccgcggc ggggacggcc
    16201 cgcgcacggg cgtggatgtg cctggtctgc gggttcgtct accgcgagga cgagggcctg
    16261 cccgaggagg gcatcgcgcc cggcacgtcc tgggacgaca tccccgacga ctggtcgtgc
    16321 cccgattgcg gcgtgagcaa ggaggacttc gtgatggccc ccatggactg ggagtgagca
    16381 cagtgcagac cctcgccgat cccgcggacg tgatgctgcg gctgctggca cccgaaggaa
    16441 agcagaaccc ctacccgctg tacgaggaga tgcgcgcgca cgggccgctg gtcgacctga
    16501 acggcgcgca cgtgttcgcc accggctacg ccgaatgcgc gcgggcgctg cgcgagcccg
    16561 cgatgctgtc caccgacgcc gccgtccagg accggaagat gccgggctgg cgggagcact
    16621 cgtcgtggcg gtggctcacc cggaacatgc tgttcgccaa cgaccccgac cacgagcggt
    16681 accggcggtt cttcggcaac gcgttcgccg cccgcagcgt cgaggcgtac cggccgctgg
    16741 tggagcggct cgcggccgag gccgtcgagc acgtcgccgt gctcggcgcg ggctgcgcct
    16801 ccgtcgacct ggtccccgag ttctccttcc ggttcgcggc ggacgtcatc ggcgagctgc
    16861 tcggcatccc ggcggacgac cgcaggcgga tgcgcgggat catcggcgac atcaccaccg
    16921 cgctcgaccc catcggcgac ctgtccgagc tcgaccgcgg ggacggcggc atggaccggc
    16981 tcgccgagta caccgccgaa ctcgtcgcgc agcggcgcgc cgcacccggc acggacctga
    17041 ccagcgcgtt cgtccgcgcc cgggacgagg gcggcgagct caccgaggag gagctgatcg
    17101 ccaacctcat gctgctcacg gtcgccgcga ccgaggcgcc gcaggacctg ctgagcaaca
    17161 tggtgcggct cgcgctggag catcccgcgc acggggcgcg gctccgcgac gacccgtccg
    17221 cggcgcccgg cttcgtggac gagacgctcc gctacgaccc ggccgtgcag gcgctcaacc
    17281 gggtcgccgc ccacgacatg gactacttcg gcatgaagat cgccaagggc accccggtga
    17341 cgctgctgat cgccgcggcg aaccgggacc cgcggcgctt ccccgaccca gccgtgttcg
    17401 acccgtcccg ctccggggac cagccgctca cgctcagcgg cggcgggcac tactgcctcg
    17461 gcgccgccct ggcgcggatg tcggcggaga ccgtcgtgcc gatgctgctg cgccggttcc
    17521 ccgccctgga gctcgccggc accccgacgt tccgcgacca gctcgtgcag cgggggcacg
    17581 cgacgctccc ggtcgtcacc gggtgagcgc atcgcgccgc accgcaccgc acgcacgtca
    17641 ccgttctgct cgctcccagt ggaaggaagt ctgatgaccg gtatcaggga cgggatgagc
    17701 gacgccgaac tcgcggcgtc cctcggatcc ggattcacca gtgagcacgc cgaggtcaac
    17761 ggggtccggc tgcactacgt ggccggcggg acgggctccc cgctggtgct gctgccgggc
    17821 tggccggaga cctggtggga gtaccgcaag gtcatgccgg ccctggccga gcgccaccgg
    17881 gtgatcgccg tcgacatccg cgggatgggc ggttcgagcc gtcccgaggc gggctacgag
    17941 aagaaggcga tggcgcggga cgtgctggag ctgtgccggc atctcggcca cgagcgggtc
    18001 gcgatcgccg ggcacgggat cggctccatg gtcgcgttcg cgttcgcggc gtgccatccg
    18061 gaggcgtgcg accggctcgt catgatcaac accacccaca tcgacgagtc ctacctcgag
    18121 ttccggatca tgccgcggcc cggcgagccc ggcccgtacc ggtggtggct gggcttcaac
    18181 ctggtgcccg acttcccgga ggccgtgctg gagggccgct accggcacat gatcgactac
    18241 atgttcgggc tgagcctgat cgacccggag gcgatcccgg agcgggaccg cgaggtgtac
    18301 gcgcgcgcct acgactcggc ggacgcgatc cgggccagca agaagtggtt ccaggcgtac
    18361 cagcaggaca tcgcggactt ctactcctac gacaagatca cggtgcccgt cctcgggctc
    18421 gcctacggcc ccttctacgc gtacatgcgc gagaagctcc cgcagcaggg cgtcgacgtc
    18481 cgcgtcgtcg agatcgaggg gagccgcaac tacctcgtcg aggagcagcc gcaggccgtc
    18541 atcaaggccc tcgaggagtt cctggactga gcccggacgg gcgggacgcg caccgcaccg
    18601 ggctcggcgc cccggtggcc cgggggagac ccctccgggc caccggggcg ctgtgatgtg
    18661 cgtctccgaa caggtgggtt gtgttttcca actcaccgtt gttacggtcg cgtcaccatc
    18721 gcgaaccgcc cgccgaaccc cggaggaaac cgtgagtccc tcagatgcgc agaccgcgag
    18781 ctcggtcgcg cccggcgagc cgggccgcgg gcccggcggc ggaccgggac gggcggcgcc
    18841 gttcggcgcc gtcttcgcga tcgtcgcggc cggggtcgcg atgtccaacc tcgacctgtt
    18901 catcgtcaac gtggcgctgc cgcaggtcgg ggaccacttc ccgggcgcct cgctggcgtc
    18961 cctgtcgtgg atcctgaacg cctacgccgt cgtcttcgcg gcgctgctgg tgcccgccgg
    19021 cggcctcgcc gaccgggccg gcgccaagcg cgcctacctg ctcggcatcg cggtcttcac
    19081 cgtcgcgtcg gtcgcgtgcg cgctggcccc cggcgtgtgg tggctggtgg cggcgcgcgt
    19141 gctgcaggcg gcgggcgcgg cggcgctcat cccctcgtca ctggggctgc tgctcgcggc
    19201 ggcgcccccg gaacggcgca tggccgccgt ccggggctgg acggcgatca gcggcctcgc
    19261 cgccgcgctc ggccccgtca tcggcgggct gctcaccgag ctcgactggc gatgggtgtt
    19321 cctcgtcaac gtgccgatcg gcgccgccgc gatcatcgcc ggggcgcggc tgctgcccgg
    19381 cgcgcccgcc cgcccggacg cgcggcgacc cgacctgctc ggcgccgccc tgctcacggc
    19441 cgggatcgcg ctcctcgccc tcggcgtcgt ccgcagcgag gcgtggggct gggcgtcggt
    19501 gcaggtcatc ggggtgctgg ccgcggcggt cgtggttctc gccgggttcg tcctgcggtc
    19561 cgcgcggcac cccgcgccgg tgctcccgct ggacgtgctg cgcgcccccg cgttcagtcc
    19621 cgcctcgctc gccaacatcc tgttcgcggt cgcgttcgcg gcgatgctgc tgtcctgcgt
    19681 gctgtggtgc caggacgtct ggcagtggtc ggcgctgcgc accggcctgg ccatcacccc
    19741 cggcccgctc atggtcccgg cgctcgcgat cggcggcgcg cccctcgccc gcaagatcgg
    19801 cgccgggccg ctcgccctcg cgggctgcgc ggtgttcgcc gccggcatcg cctggtggat
    19861 ctggcggatg gccgacggct acctcctcgg catgctgccc ggcatgctgc tcaccggcgt
    19921 cggggtcggc ctgacgctgc ccacgctgat cggcgcggcc gtcgccgcgc tgccgccgca
    19981 gagcttctcc accggctcgg ccgtcgtgac catggcccgc caggtcggga cggtcgtcgg
    20041 cgtcgccgcg ctgatcgccg tgctgggcgg cggcgaggcc gcgcgctccg ccgccgactt
    20101 cgacgccggc tgggtgctga cgatcgccgc gacggccgcc gcggcggcgg catgcctgtt
    20161 catcccccgc gcgcgcccgc gctgacccac gttcccccca agcgaaagct catcccgagg
    20221 aggttgtcat gcgagacgcg gtgatcgtcg aagccgtccg taccccggtc ggaaagggca
    20281 aaccgggcgg tgcgctgcac ggtgagcact cggtggacct gctggcccgc acgctgcaga
    20341 gcctgatcga gcggtccggc atcgatccgg cgacggtgga cgacgtcgtc ggcggcatcg
    20401 tcagccaggt gggcgaccag gcggtcaacg ccacccggtc cgccgtcctc gccgccgggt
    20461 tccccgagag cgtgcccgcc acgacggtgg accggcagtg cggctcgtcc cagcaggccg
    20521 cgcacttcgc cgcccagggc gtgatcagcg gcgcgtacga cgtcgcgatc gcgtgcggcg
    20581 tcgagtcgat gtcgcgcgtc ccgatggggt cgagcgtgct gcccggcagc gacccgttcg
    20641 ggccgcagat ggccgcccgc tacccggacg ggctggtcgg gcagggcatc agcgcagagc
    20701 tgatcacttc ccgctggaag ctgacgcgcg ccgacctgga cgagttcgcc gtgcggtcgc
    20761 acgcgcgcgc gtccgccgcg tgggacgccg gcgagttcga ccgggaggtc gcctggacgg
    20821 ggatgcggga cgagtccgtc cggccgggca cgtccatgga ggtgctgtcg gggctgaagc
    20881 ccgcctacta ccgcgacgac tacgccgagc ggttccccga gatcggctgg agcatcaccg
    20941 ccgggaacgc ctcgccggtc aacgacggcg ccgccgccct gctcatcatg acctccgaga
    21001 cggcacgcaa gctcgggctg cgcccgcgcg cccgcttcca ctccttctcg gtcgccggcg
    21061 ccgacccgct gctcatgctg accgcgatca tccccgcgac cgagaaggtc ctcgcccgcg
    21121 ccgggctgtc catcgacgac atcgacctgt tcgaggtgaa cgaggcgttc gcgcccgtcg
    21181 tgctcgcgtg gcggcacgac accggcgccg acctggagaa ggtcaacgtc cggggcggcg
    21241 ccatcgccct cgggcacccc ctcggcgcca gcggcgcccg cctgatgacg accctcgtgc
    21301 acgccctgga ggaccgcggc gcccgctacg gcctgcagac gatgtgcgag gcgggcggcc
    21361 tggccaacgc cgtgatcatc gagcgtctct gacccgcccc ccgcaccccg gttcgggccg
    21421 tccgcactcc acggtggcgc acgggcggcc cgaaccggtc ggaaaaccca accgacccgc
    21481 ctaagctgga gtgatgggca aggacgccgt ccctcgggaa tgctcggtcg ccgacgcgct
    21541 gcaggtcgtc ggcgagcgct ggacgctgct ggtcatccgc gagctggtgt acggcgtgcg
    21601 gcggttcgac gggatcgtcc gcaacaccgg cgccgcccgc gacatcctga cgacccgcct
    21661 ccgcaagctg gaggacgcgg gcatcgtgcg gcgggagccc tacagctccc gccccgtccg
    21721 ctacgagtac cgcctgacgt ccaagggctg ggagctgagc gacgtcctgt cggtcctgat
    21781 gaaatggggc gaccggcacc tcaaccccga cgatccgccg gtccgctgga tccacacctg
    21841 cggcgagcgc ctcgaacccc aggtcgtctg cacgcactgc ggacgtcccg cgctggaggg
    21901 cggccacccc accggccgcg gcgcccggac cgcctaacgg gcgcccctgg gctcgcggac
    21961 caggagggtg cccgcgagca ccaccagccc cgacatcgtc aggacgaact gggccggggc
    22021 catcccgaac ggcgtggcgt ccgcgccgtc cagcaggtcg gccgccgcgc ccgacagcag
    22081 cgccgcgagc gcgagcccga accgcagcgt ggcgtggaag gcggtgagcg cgaggttgcg
    22141 gtccccgccg ccgaggcgtt cctgcaggta ggtgatgccg ccgacgagcg cgctcgtcgc
    22201 cccggcgccg aacaggaccg ccccgatgaa cgaccaggcc ggcgacgcga gcccgcccat
    22261 cagcgcgatc accacgccct gcacgaccgt cccggtccgg atctgcgaca gcaggtccca
    22321 gcccttgcgg tggacgagca ggagcccgat cagggcgccg accccgaaca gcaccaccag
    22381 cgcgccgaac ccgaccgcgc ccgcccccag gacgttgcgg acgaacacga caccgagcga
    22441 gaacagcgcg ccgaggccga gggcgatgac ggcgacggcc gggatcacgc cccgcacggt
    22501 cggcagccgc agcgccgcga agaacccccg ctgcgtctcg gtctccttct cggccgcgcg
    22561 ccgctcgtgc gggccggggc cgaggtcggg gatggcgcgg acggccacgt aggacaccag
    22621 gtaggtcagc gcgttcagcc agaacaccac cacgtaccgc cagtgcccct cccagcccgc
    22681 ctggttcgac gcccacagga tcagcccgaa cgcgcccgcg ccgaccggga tcatgccgta
    22741 cgaggtcgcc atcgtgatgc cgttcgcgac ctccagcgtg ctcgtgtcgt gctcgtcctc
    22801 gtcgtcctcg atgaggaacg gcacggcggc gtcccgggcg ggcaggaaga tcaggcccac
    22861 gacctcgatg aggaacgccc agaagtacac ccaccacagg aacggcagca gcggcagcgt
    22921 caccgccatc cccgccctga tcaggtcgga cttgagcatc acgctgcggc gccgccaccg
    22981 ggtcaccacc cgggcggcga gcggggcgcc cagcgccgac ggcagcaggc gcagcaccag
    23041 cacgccgccg acggccgtcg tggagccgga gatctccagg acgaagtaca tcagcgcgag
    23101 ggtgcccatc cagtcgccga aggacgagac ggcctgcccg acgatgagca gccggaagtc
    23161 ccggcggttc agccgatcct tgagtcccat gcgggctccg tccccggtcc gtggcgcccc
    23221 ttcgcatcat gcgcgtccgg ggcggatccg cgcagcaggg cggcgaggcg cgcggcggcg
    23281 ccgtcccagc tccaggtgtc gcgggtccag cggcgccccg cggcgcccat cgcgcgggcc
    23341 cgtccgggat cggccagcag ccggtgcagg gcgagcgccg gctcgtcggg gccggacgcg
    23401 tcgacgagca ggcccgtccg cccgtccacg agggactcgg ggctgccgcc cgaccggccg
    23461 acgatcaccg ggagcccgga cgcggacgcc tccagcgtcg acagcccgag cccctcgacc
    23521 tggagcccgc gacggttgtc ccggcacggg agcgcgaaca cgtcggcggc cgcgtagtag
    23581 agcggcaggt cggcgtcgga gacggggccg gtgacggtga cggcgccggg cgccgtccgg
    23641 tccccgagtt cggtgaggcg ccgccgcatc ggaccgtccc cgacgatgac gagccgcgcg
    23701 tccgggtacc gccgcagcac gtccgcccac gccctgatca gcatgtcgtg gcccttgcgg
    23761 cggacgagcc gcgcgacgct gagcacgacg ggaccggacc cgagcgcgtg ccgccgccgg
    23821 atctccgcgc cgtccaggcc cggccggaac cggtcggtgt ccacggcccc cgcgagccgc
    23881 acgagccggg tgcggtcgcc cagcgcgtcc tccagctcgg gcagcgtgga cgcgcacagg
    23941 tgcgtgagcg cgtcgaacga cccggccacc gcgtgcagcg cccgccgcgt cggcacggcc
    24001 cggaaccagc ccagctcctg cccgtgcgtc gacccgatca gccgccgcac ccccgccgcc
    24061 cggacgagcg gcgcgtacat cgcgaacggg gcggcggcgg gaatccaccc ggcctcgatc
    24121 cggtgccgcg cgacgagccg gcgcagcccg cggaacagca ggtagccgcg ccgccggacg
    24181 accgggaacg gcagcgccgc gtcgaactcc gcggcccccc gccacgcggg cgccaccacg
    24241 agcagccggt cggcgggcaa ccgccgcgcc agctcccacg tgaacgtctg caccccgccg
    24301 ggctccgggg ggaagtgccc ggtcagcacc agggtccgcg ggatgtccat gcggacacgc
    24361 ttcccgcgca gcgccgcgcc atgcacgcac cgcgccgccc cggcgaccga gcgtgatgcc
    24421 cgccccggtg cggccggtga cctggagacg ccgcgcggtg gttcggggcg cggtcagccg
    24481 atgatcacgc ggtccttcgg ggccttcggg tcgggcgtcc agccgtcgtg gcccgcgtcg
    24541 gcgcgccaga cctcgcccgc gtgccgcacc tcggtcagcc cgtacgcgtg cgcgtgcgtc
    24601 accgcccacg cggcgaccgc ccagcccatc cgctcgcccg gcaccagcac cgccgtccac
    24661 cgggcggccg ggtccggtgg tgccgccgcg ccgccgcccg cggcgcgcgg gccgtccacc
    24721 ttcaggccgc cgccgaacgc ccgccgcatc tcgcggaccg cctcggcgcg gcgcggctcg
    24781 gtccgctggt ccggcgggaa ccagcagcgc gccgcggccg gctcccgacc ggtgaacgcc
    24841 gccgccagca gctcgccgtc cggctcgtgc tgggcgtaca gctcgccgtc ggcgctgcgc
    24901 tgcaccgcct gcgcggagac gtgcaggtcc ttgtcgaggt agtccttgac ctggacgagc
    24961 ccgtcgaaga acttgctcgt cgacacgacc gggtcgcgga gctgctccgg ggtgccccag
    25021 ccctgcgagg ggcgctgctg gaacatgccc accgagtcgc ggtcgccgcc cgcgaggttg
    25081 cgcaggtgcg actcctggat cgcggtcgcg tacgcgatca ccacggcccg ctccggcaac
    25141 tccttgcgga acgccaccgc cgcgatcgtg gccgagttcg cgccctgctc caggctcagc
    25201 gacatcttcc ccgcgccggc gcccacctcg cagcccgtcc cgtgcaggta cgggcgcgtc
    25261 cactggtacg tcgcgtaccc gccgacgccg agcagcacga cgaagacgga cgtgatgatc
    25321 gcccagcgct tacggcgccg gggcgcacca cgctccggcc cctgctccgg ccgcgacttc
    25381 gacctcgccc atacagccac gcgaagaccg taccgggaac cggccaccag taagctcagt
    25441 caacatgacc gaaacgttca ccagcccgat ctcccacgtc atcgacgact tgtgggagcg
    25501 gcgcgccgac ctcacgccgg acgacgccga cgcgcgcgcc gcgatcaccg cggccgtcga
    25561 ccagctcgac gccggggagg cccgcgtcgc cttcatcgac cccgcgaccg acgaggtcgt
    25621 cgtggacgaa cgggcgaagc ggtcgatcct gctcagcttc aaggtgctcg gcatggtgcg
    25681 ttcgcaggtc ggcgacttcc agtaccacga ccgcatcccg ctcaagagcc gcctcgacgg
    25741 cgtccgggtc gtgccgggcg cgatcgcccg gtggggcgcc tacctcgcgc cgggcgtcgt
    25801 cctgatgccg tccttcacca acttcggcgc ctacgtcgac tccggcacca tggtcgacac
    25861 ctgggcgacc gtcgggtcgt gcgcgcagat cggcaagaac gtgcacctgt ccggcggtgt
    25921 cggcatcggc ggcgtgctgg agccgccgaa cgccaagccc gtcatcgtcg aggacgaggc
    25981 catgatcggc agccgctcga tgatcgtcga gggtgcccgc gtcggcaagg gcgcggtcgt
    26041 gggctcgggc acgaacctgt cggcgtccat gcccgtcatc gacgtcgaga ccggcgagga
    26101 gatcagccgc ggccgcatcc ccgactggtg cgtcgccgtc ggcggcaccc gcaccaagga
    26161 gttcaagggc ggcacgtacg gcctgcccgc cgtgctcatc ctcaagcggc tcgaagaggg
    26221 ccagcggcac gacaaggcgg aactgaacga catcctccgc gaccacggcc tcggctgaac
    26281 cacccggata ctccccgttc ctcgaacgcc tccagggaac ggggaggccg atcaacgtca
    26341 ggggccgggg ttctcggtga ccttcagcgg ggcggcggtg aggacggcca gggcggcggc
    26401 gtagccggcg cccggggtca ggtcggccag ccggacgggc gccaccgccg cgtctccctc
    26461 ccaggacagg acctcggggg ccgtgccggg cgcggagagg cgcaggtcgg tcatgggggc
    26521 cgccaggccg tgcccggtgg ccttcaggac ggcctccttg cggctccagt agacgtggaa
    26581 ggcgcggcgc cgctcctcga gggggagggc cgcgaagtcc tcccgctccg gtgcggccag
    26641 caccatctcc gcgagccggt cgatgtcgcg gtcgctctcc cgctcgacgt ccacgccgat
    26701 ccggacgccc tcggcgacgg cgagcacgac gcggtcgccg gagtgcgaga gcgagaagtc
    26761 gacgtcgtgt ccggggagcc ggggcttgcc gtggtcggcg ccgcagtgcg ggcactcggt
    26821 ggtgaacgcg atcgcgtccg gggacaggcc ggtgcgggcg gcgagcgcgg tgcgggcgag
    26881 gaagcggccg gtcacgaacc gggccttgtc ctcgggacgg aggaagcggt cgtagcgggt
    26941 gcgttcggcg gcgtgcagaa ggtcgcgcat gtgcggttcg tcggcggggg ccgaccactg
    27001 cacctcgatg ggcgtctcca cgacgatgat cctatgccgc gtacgcttgt cgctcatgcg
    27061 gcttgatctg ttctcggacg tgacggacct gacggcggcg atcgtcgaca tcgagtcggt
    27121 gagcggtgcg gaggggccgc tcgcggacgc ggtcgaggaa gcgctgcggg cgctgccgca
    27181 cctcgcggtc gagcggaccg ggcacaacgt cgtcgcccgc acggagctcg ggcatgcgga
    27241 acgggtcgtc ctggccgggc atctcgacac cgtgccgctg aacgggaacc tgccgtcgcg
    27301 cgtcgagggc gaccggctgt acgggtgcgg cacgaccgac atgaagagcg gtgtcgcggt
    27361 ggcgctccgg ctcgcggcga ccgtgccgga gccgacgcgg gacgtcacgt tcgtgttcta
    27421 cgagtgcgag gagatcgagg cggagcgcaa cgggctgcgg cggctcgccg ccgaacgtcc
    27481 cgaactgctc gccggtgact tcgccgtcct gatggagccg acgggcgcgc tcatcgaggg
    27541 cgggtgccag ggcaccatcc gggtggaggt cacggccacg ggggagaggg cccacagcgc
    27601 gcgcgcttgg atggggtcca acgcgatcca ctccgccgga cgcatcctgg acgtcctgcg
    27661 cgcgtacgag ccgacgcgtc cggtcgtgga cgggctcgag taccacgagg ggctgaacgc
    27721 ggtgttcgtc cggggcggcg tcgcggggaa cgtgatcccg gacgagtgcg tcgtcaccgt
    27781 gaactaccgg ttcgcgcccg acaagtcgct cgatgaggcg gaacggtacc tccggcgaat
    27841 cttcgacggc ttcgcggtga aggtcacgga cgcgtcgccc gccgcgcgcc ccggcctgac
    27901 gcacccggcg gcggacgcgt tcgtccgggc ggcgggcgcg gaggtgcggg ccaagctcgg
    27961 ctggacggac gtcgcgcggt tcgcggaact cggcgttccg gccgtcaact acgggccggg
    28021 ggagccgacg ctcgcgcaca ccaaggacga gtacgtcgag atcccgctga tcggcgactg
    28081 cgagcaccgg atgcgcgcct ggctgaccgc ctgaacggtc acgcccgcat gccccgtcac
    28141 ttcccggtga aggtccgccg aacgcggaaa cggggaggtg gacgggcccg gcgcgccgtt
    28201 acggtggggc aatgacatcc gaagacacgc gccgatcccg gcggcagggg cccgccatgc
    28261 tgcgcgggcg cgccgtcccg ccgacgacca ccgaccagcg gctgctcgac gcgcgcggcc
    28321 cggccgactg ggtgcacgcc gacccgtggc gggtgctgcg catccaggcg gagttcgtgg
    28381 agggcttcgg gctgctggcg gaactgccga aggcggtcag cgtcttcggc agcgcccgca
    28441 cgaagccggg gacgcccgag tacgacatgg ccgtcgacat cggcgcccgg ctgcacgacg
    28501 ccgggtacgc ggtgatcacc gggggcggac cggggatcat ggaggcggcc aacaagggct
    28561 gcgacgagaa
//
