LOCUS       NZ_CP044407            22739 bp    DNA     circular CON 28-JUL-2024
DEFINITION  Actinomadura sp. WMMB 499 strain WMMB499 chromosome, complete
            genome.
ACCESSION   NZ_CP044407
VERSION     NZ_CP044407.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura sp. WMMB 499
  ORGANISM  Actinomadura sp. WMMB 499
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Draft genome of Actinomadura sp. WMMB499
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2019) Pharmacy, University of Wisconsin-Madison,
            777 Highland Ave., Madison, WI 53705, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. Oct-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008824145.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 05:00:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,413
            Genes (coding)                    :: 8,251
            CDSs (with protein)               :: 8,251
            Genes (RNA)                       :: 110
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 64 of 162
            Pseudo Genes (incomplete)         :: 108 of 162
            Pseudo Genes (internal stop)      :: 10 of 162
            Pseudo Genes (multiple problems)  :: 19 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:12:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5915929
            Orig. end                         :: 5938668
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044407.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Genome not circularized.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22739
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="17"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22739
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22739
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12739](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12739)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            294..1523
                     /locus_tag="F7P10_RS26645"
                     /old_locus_tag="F7P10_26645"
     CDS             294..1523
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7P10_RS26645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7P10_26645"
                     /product="hypothetical protein"
                     /protein_id="WP_151013271.1"
                     /transl_table=11
                     /translation="MRQDARARDGGVVHQVAGDQHVHHHNHPEGAAPQVERIARSITDP
                     FDRARALGAVAKAEMTDHQERAQALLDDAERIARSITDPYRRATVLGTVTDVVAGRAPE
                     RAQALLDEAERLTDSITDADLREQTLMFLARAAAGYAPAEAERIARSIPGPTCTWALKG
                     VAAVVMETAPAEAERIARSITNPTARAPALGQVAGAVWELDPQHARALLAEAEHIARTL
                     VPGFSRARALSEIAGAVAGHASYRARGLLTEAERITRSDTKTFQKWALPDVAENLAALD
                     PAEAQRIVRSIADPYDRTKALGKVTETIAGFDPATAERIARSIRRQHIDRFVTKFFPNK
                     WRVAQPLEFYGAQALAVVAGAVRNSDPQHALALLNEAERTARSITFIDDREEVLLHIVQ
                     AMTRQQPRKR"
     gene            1709..2857
                     /locus_tag="F7P10_RS26650"
                     /old_locus_tag="F7P10_26650"
     CDS             1709..2857
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1053: beta-lactamase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017569060.1"
                     /locus_tag="F7P10_RS26650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26650"
                     /product="serine hydrolase"
                     /protein_id="WP_151013273.1"
                     /transl_table=11
                     /translation="MPDERGPDRVRRVLDGHIGAGLAPGLVALVRRGAETRAVVLGSMA
                     AGGGAPMRRDALFRVLSLTKPVTAVAALSLVEDGTLALDDPVDRWVPELAGPRVLRRPD
                     GPLDDTVPAARAITVRDLLTFRLGTGAMTEPCPLGDAMAAAGVAPGPDPTELAPGEWLG
                     RLGALPLAYQPGARWLYDTGSDVLGVLLARAADRPLADLFRERVFEPLGMRDTGFHVPS
                     GEAHRLAASYRPPDGSGVLTPRDDPRDRPPAFPSGAGGLVSTADDYVTFFRTLLDGGGP
                     VLSRESVAAMTTDRLRAAEKAGAGMFLQSGGWGFGVAVETRDDPPESRAGRFGWMGGLG
                     TMAFADPSADLVAVLFTQVELGSPESARVFDEFREVAYAPAE"
     gene            2916..3854
                     /locus_tag="F7P10_RS26655"
                     /old_locus_tag="F7P10_26655"
     CDS             2916..3854
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017589932.1"
                     /locus_tag="F7P10_RS26655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26655"
                     /product="DUF5996 family protein"
                     /protein_id="WP_151013275.1"
                     /transl_table=11
                     /translation="MGRQGWPRLRVADWQATRDTLHMWAQIVGKVRLAHAPLVNHWWNV
                     TLYVSPRGLTTSTIPYGTGAFDVEFDFVGHRLRLRGSDGTDEGFALEPMTVAEFHDRTM
                     RALGRLGVETRIQGHPNEVDPAIPFAEDDVHASYDADAAHLFWRQLLQGSRVLGEFRSR
                     FVGKVSPVHVFWGALDLACTRFSGRTAPDHPGGAPNCGDWVMVEGYSRELSSCGFWPGG
                     GEEGAFYAYAYPEPEGFAARSVRPSAAFYSAENGQFLLPYEAVADDPDPDAALLAFLQD
                     TYEAAADLAGWDRDVLEADPARWAHKTNHRV"
     gene            3867..4313
                     /locus_tag="F7P10_RS26660"
                     /old_locus_tag="F7P10_26660"
     CDS             3867..4313
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017609926.1"
                     /locus_tag="F7P10_RS26660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26660"
                     /product="VOC family protein"
                     /protein_id="WP_151013277.1"
                     /transl_table=11
                     /translation="MVTREQLPAPTEGLVLTHFLTVRDVARSRAFYADVLGGEVVLAEN
                     PAIVRVANTWIIMNPGGGPTPDKPDVTLRAPEPGDPVTAFMNVRVADIAAFHARATSLG
                     ARFLTEPIDRKAEIRCYMVDPDGRLIEVGQATGMLHGVYADPPA"
     gene            complement(4318..6054)
                     /locus_tag="F7P10_RS26665"
                     /old_locus_tag="F7P10_26665"
     CDS             complement(4318..6054)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="F7P10_RS26665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26665"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151013279.1"
                     /transl_table=11
                     /translation="MRVPPAARLLRRHLRGRGPALRGLAAWSVVEGLPVLAGGLLLARA
                     VDHGFLAGRPGTGLAWLAVLAVLYLCGAEATRRIYPRLATTVEPLRDSLVTDVVTASLH
                     RTGGTGGEADGTAGGAGTGVAQVAEQAEAVRVLLGTALRNVRQLLAAGIAALVGLALLS
                     PPLALAIALSVAVAVGVFAAFLGVQIRRYRDVVRQAERIGESGAAIVAGVRDVVACAAE
                     DRAARTVAASIDAQAAAMRAFARSRLVRLPVLALGVHLPLLVLLALAPSLIDGGRLTTG
                     EVAGAAGYLITGLQPGIVLLVDAGGTLLLSLAVILGRLAETGAGGTAPALPARPGPVPA
                     SSDIELDRVTFAYSPRAAPVLTGLSLRIPAGTHLAVVGPSGTGKSTLANVLTDLVRPQR
                     GTVTLGGVPLPDVDRDRLRSAVTLIPQESYIFAGTLRENLAYLRPGATTAQLDEAARAV
                     GLEETLRRFGGYDAAVPPGGGSLSHGERQLVTLARAYLSAAPVLILDEATCHLPPAAEA
                     RAERALAGRGRTLVVIAHRISSAERAHRVLLLDSSGPIVGTHRTLLDLSPLYAELVGHW
                     RT"
     gene            complement(6051..7844)
                     /locus_tag="F7P10_RS26670"
                     /old_locus_tag="F7P10_26670"
     CDS             complement(6051..7844)
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.4"
                     /locus_tag="F7P10_RS26670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26670"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151013281.1"
                     /transl_table=11
                     /translation="MTGRVRTEPAGGETAPRTEAPAAPPAPAVLRAGGRRLLRAAMRRT
                     RALMGVLVLCTLLRVLATLATPVMLARAIDAVHTGRPPGGALTGLAVVLAVAALADAGE
                     DLAGSYCGSHVTAWLRHRLIGRVLELGVPGRRRFPTGDVLSRLTESASGPAAFPVQLVS
                     VAATLATTAGAVVALGLIDWTLALAFALGVPPAVVVLRVFVARAGEPFADYARHQAAVA
                     TRLLDAHQGIRTIRASGTADREVARILRPLPLLRDAGHRTWAVQGRVGWRLALLAPLLQ
                     VAVVGVAGLRLATGDITPGGLVAAASYTAMAVGAAALFDTVVALLNCEVSAGRVQEVLD
                     TVPAVAPPPRPVALPDGPGRLSLRDVTVRIGDRTVLDRLDLTVPAGTGVAVVGASGTGK
                     SVLVSLVGRLLDPQEGRVELDGVPVTAVAPPELRRAVAYAFERPALLGATVHDTIAYAR
                     PEATRAQVRRAARTAAADDFVRALPDGYDTPLDRAPLSGGELQRLGLARAALTGARVLV
                     LDDATSSLDTATEMKVTRALQRLLARRTSLVVARRPATAARADLVAWLDGGRIRALAPH
                     AELWADPDYRAVFGTAPGPGG"
     gene            complement(7995..8150)
                     /locus_tag="F7P10_RS42705"
     CDS             complement(7995..8150)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038147.1"
                     /locus_tag="F7P10_RS42705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="VenA family class IV lanthipeptide"
                     /protein_id="WP_176611670.1"
                     /transl_table=11
                     /translation="MDIFDGDLVAELQDLPETDPIEIDGIQLGGTCTCAGLLTLLNTVC
                     VGVSCA"
     gene            complement(8157..10004)
                     /locus_tag="F7P10_RS26675"
                     /old_locus_tag="F7P10_26675"
     CDS             complement(8157..10004)
                     /NRPS_PKS="Domain: Abhydrolase_1 (378-504). E-value: 5e-10.
                     Score: 31.3. Matches aSDomain:
                     nrpspksdomains_F7P10_RS26675_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024109.4"
                     /locus_tag="F7P10_RS26675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26675"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_151013282.1"
                     /sec_met_domain="PF00561 (E-value: 1.3e-07, bitscore: 30.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Peptidase_S9 (E-value: 1.1e-19, bitscore:
                     69.7, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAVPALPAIPSRFGFAFSGDGRWATCLSTVQDRVTLERWDLTGP
                     VPSGRAVGTAGDPVDRTSRPIPLDDGRVLVARAATGAGGAPAGHGTVLAVRPGGPDGPD
                     GAAARSWRIAPMLAGYPLAGPGSPQTLVVVTVEDERHSRIWVLPHGAGPPEPVVRIPGV
                     LSGGVWLDDGRTLALDHAGDGHRTDGIVVDLRERSWRRIWTVSDTTSDRIVACDRAARR
                     LAVTTGGPGRAVPAIGLWSPGGGRVRFPASLNRPGRARTPLAFGGGERLLVCEDVGATS
                     RLLIHTPADDRVEPVPGPRGVLSPPASWTGGRIHLRFSAPHQPPTLATAHRAGWSLARR
                     PAGTAARWAGADLVELPGPDGPVEAIVYGGARWHESDRVVLALHGGPLAAWRLEFDPLF
                     QHLAAAGIAVVAPNQRGSTGYGERHLRAVVGDWGGPDLADVVHLGRGIAERRRGTGARV
                     REPVLLGASYGAWLALLAACRHPDLWAACVALAPFTSPASLYRDAAAPVRDRVAALHRP
                     GGTGRDARRDVLAACGALTAPLLVAHGTRDEVVPVGQSRALRRRLLELGRTEGPGFEYL
                     EVDDDHTAVVQAWPADLRTSVVRFCLGAGRTLVPSKERR"
     aSDomain        complement(8493..8870)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS26675_Abhydrolase_1.1"
                     /evalue="5.00E-10"
                     /label="F7P10_RS26675_Abhydrolase_1.1"
                     /locus_tag="F7P10_RS26675"
                     /protein_end="504"
                     /protein_start="378"
                     /score="31.3"
                     /tool="antismash"
                     /translation="VVLALHGGPLAAWRLEFDPLFQHLAAAGIAVVAPNQRGSTGYGER
                     HLRAVVGDWGGPDLADVVHLGRGIAERRRGTGARVREPVLLGASYGAWLALLAACRHPD
                     LWAACVALAPFTSPASLYRDAA"
     CDS_motif       complement(8568..8621)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F7P10_RS26675_0001"
                     /evalue="1.10E-02"
                     /label="NRPS-te1"
                     /locus_tag="F7P10_RS26675"
                     /protein_end="479"
                     /protein_start="461"
                     /score="8.4"
                     /tool="antismash"
                     /translation="VLLGASYGAWLALLAACR"
     gene            complement(10001..12739)
                     /gene="lanL"
                     /locus_tag="F7P10_RS26680"
                     /old_locus_tag="F7P10_26680"
     CDS             complement(10001..12739)
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="F7P10_RS26680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26680"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_218040148.1"
                     /sec_met_domain="Pkinase (E-value: 3.3e-19, bitscore: 68.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 1.7e-46, bitscore:
                     157.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDFKFSIFTAVSAADAEETPLVDALTRAIESAPGRWRIGRSGIW
                     CSAAPEEGPRRPQGWKLHVSATPASAPEVLARALPVLLAGEARSAFKFAATVDFVAALN
                     ARNTSRGHSGKFMTIYPESDTEAVRIARELHEATQGLAGPRVLSDRPYAPGSLVHYRYG
                     AFVEERRLTNDGFYTWTILDPDGKPVEDQRTGKYTPPSWVTSPFPDNGMNGTRRSREAG
                     AIMLGEHFAVREAIRHTNKGGVYRAVDRRTGDPVVIKEGRPHVAADMDGRDTRDRLRAE
                     ARALERLAGTGLAPRLVALFPQGGHLFLAQEMIEGGPLREWAADRIVETGWGGHLPAAT
                     DMARRLVELMSDVHAAGLLVRDFNPNNIMVRPDGAPVLIDLELAVVDGEDGPRQAGTPA
                     FGAPEQLGGAAPHASADHYSLGATLCYLFTGAPPYLLDESPESRPPAERLEEWLAARTQ
                     DLDFPEHLRAMLRGLMADDPRHRWTADRAREALAARAPRRARGRDAETPWPRETVDRAI
                     GGIVDELLASMDPDAPHALWPVSCVHGAPDPCTLQQGAAGCLGALVRYAELTGDPRLPD
                     AIAAAARWIRARLADGTSRPPGLYFGTAGVSWSLLEAGLALGDERLVDDAADVAEGLPT
                     AVASPDITHGTAGLGLTALHLWSRTGSARFARRADAAADALLGTVEDREGRLMWSTPAD
                     VDSKLAGRSYYGFAHGIAGVGYFLVACAEATGRDDCRALALRIGEELLDAAVVERGTAM
                     WGAGAGDAPTAPYWCHGASGIGSFLLRLGTATGDARFLEAADRAARAVTEHAWRAVLGQ
                     CHGLSGNGDFLLDMADLTGDDRHRAAAWRLARTIVAARALRDGRLVLPDEQGEVSATWG
                     DGLSGMLGFLLRLRYGSPRLWTVDAAAATAPTTATTARGAS"
     misc_feature    12718..12732
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 20.2"
                     /tool="antismash"
     misc_feature    complement(12721..12735)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.14"
                     /tool="antismash"
     misc_feature    complement(12731..12745)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    complement(12788..12802)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.29"
                     /tool="antismash"
     misc_feature    complement(12861..12874)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 18.86"
                     /tool="antismash"
     misc_feature    12865..12885
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    complement(12921..12938)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            complement(13158..15980)
                     /locus_tag="F7P10_RS45160"
                     /old_locus_tag="F7P10_26685"
     CDS             complement(13158..15980)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1149: LuxR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024589.4"
                     /locus_tag="F7P10_RS45160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26685"
                     /product="LuxR family transcriptional regulator"
                     /protein_id="WP_151013284.1"
                     /transl_table=11
                     /translation="MTVTQGRDPLHGRVPELDAIGELLDRARGGRGGALAIVADAGLGR
                     TALLEEAVRRAGPDVRTITASGVARESGVPYAGLHRLLRPLAAEIRLLPDEHRAALAAV
                     RGGREHAEPFALYAALCELLALASRDGPLLCRADDVQWLDEVSLDALAFAARRVQDLPV
                     AVLLAARDDRPGLAGIPHLRLGPLDEDASLRVLRDAIGDAVGGALADAIVDLADGRPRA
                     IRDLAAALTPGQLSGAAAPPRALPPGSPLRALHRDRYLRLPAGAQRLVLLVVADEWVGA
                     GTLDRAAGAAGIGAADVEAARESGLLRYETDAVTVRDRLVRSSLWADATRAERTAAHAL
                     LAEVLVHDWQYTGRIWHRAAMSGGTDDVAAAELAHAAVVSQGSGRYADSWRMWQRASTL
                     TTDRTLAADRLLSAAADAWASGRPRRARAMLRRLAAFRCDGARTARADRLRGEIAAASG
                     DPATALPLLRDAAERFAADDAALALETLLWAAEAAEAAGDVPAHAEIAERAAALPLPDE
                     PWREARTRLMLDHLTGTAALHAGRYAEAARRLASATRHGSSVTDPAALAWAARAALNLG
                     DAGLAPALATAAVAAARRAGIVPLESYALSVAARCEVLLGRPPAPVAAGHDGLRLAQAT
                     RLHGHAAEQLATLALAASFDGDSGAAERHLDRLATAAGRRGLVRAAAFGGWAPACLDLA
                     ADRPSDAVARLRLPAGPGVAHPGVRLAAAPHLVEALARGGDRARAAAAFDTFRRWSEAT
                     GTPVHRALAHRCRALLADTPADAAAHFTEALRLHETAGAVFEQGRTELLYGHRLRRARR
                     PRAAREHLRTALRIFERYDAGPWTEQARAELRAAGETVAPLAVPAPAGPASVSGAAVVP
                     SRTVPGQANGFGELTPQQAHIARLVAEGATNREIAARLLLSPRTIDHHLRNVFTRLGIR
                     SRVELARMIR"
     misc_feature    15968..15980
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     misc_feature    16083..16095
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: medium, score: 22.86"
                     /tool="antismash"
     misc_feature    16091..16101
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.94"
                     /tool="antismash"
     misc_feature    16120..16137
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 14.21"
                     /tool="antismash"
     gene            16184..17473
                     /locus_tag="F7P10_RS26690"
                     /old_locus_tag="F7P10_26690"
     CDS             16184..17473
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012854983.1"
                     /locus_tag="F7P10_RS26690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26690"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_151013286.1"
                     /transl_table=11
                     /translation="MTADADGAILRKAVLRLEDRLPELADRLAAEILSGEDGRDRPEAV
                     LGDMWEVCHTGLGHGFEAILEPGGGRADLDWARRLGERRAQQGEPLEHVLRGYRLAGRV
                     FWEAVVEAVGRHDPEHIPALVRQATRTWDTIDQQSDAAADAYHRTEFALARRSEERVHA
                     IVDALLDGQGADGGLLATAGTVLGLPVTGRYAVAMLRADGGFAADVDLRPGEVGGMRFL
                     WRMRANAQVALVALGAADLDDLVGALEPCTRGHAGVSPVAESLADLGTARWLAELALRT
                     CHGPGPQVARLDRRLPDALVLSQPRLAGRLGDVALGGLGSVEPAYREVLLGTLDTWLDC
                     GGSAARAAERLFCHRNTVLNRLRKIEQLTRRRLARPSDLVELVLALSAVRLHGSGADPQ
                     AAPPAAAPQGAAQPAASLLGAARPPRTRIP"
     gene            complement(17770..18609)
                     /locus_tag="F7P10_RS26695"
                     /old_locus_tag="F7P10_26695"
     CDS             complement(17770..18609)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017579155.1"
                     /locus_tag="F7P10_RS26695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26695"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_151018307.1"
                     /transl_table=11
                     /translation="MLASAALAAGLCAVPHTALAQENPYERGPDPTESSIEAPLGSYDV
                     GEDSVSGLFVSGFGGGTVYYPEDTDETFGAVAIAPGFTAGQSSMSWYGPRLASRGFVVM
                     TIDTNSRFDQPASRGDQLLAALDYMVEDSDAADLIDPNRLAVMGHSMGGGGTLEASVDR
                     PSLKAAIPLTGWNLRKNWSQSQVPTLVVGAENDTVASVGSHSEPFYESLPPEKAYVELA
                     GASHFAPNTSNTDIAKYSIAWLKRYVDNDTRYTQFICPGPDTGWFSDISEYRSTCPM"
     gene            complement(18829..19998)
                     /locus_tag="F7P10_RS26700"
                     /old_locus_tag="F7P10_26700"
     CDS             complement(18829..19998)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893664.1"
                     /locus_tag="F7P10_RS26700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26700"
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="WP_151013288.1"
                     /transl_table=11
                     /translation="MSNEITVIGGGLAGLVAAIACAEGGASVTLHEAHRTLGGRGRATP
                     APYVAHEGAHVFYADGPHWSWLTERGLAGPLGTYNTRMMTHTFFRADGRLRRVPPAGFL
                     RMAGRTPLLRAPVDRDFRSWASARFGERTAERAASAISVVTYDADTGRLSAAFVWELIG
                     RVFAPKRPAVRWPIGGWQAVLDRLAARAAGLGVRVELGSRVTAPPDTPTIVATELASAR
                     ALLGDASLTWESGHYAMLDLAVRDDRRDAFIVFDLDEGGFHESYSMQDPSTVPAGETLF
                     QIGMPVREGEGGAGARRRLDALADAAVPGRGDRTTWSRTATARGRTGALDLPGRTWRDR
                     PAIDRGDGVFLAGDMVAAPGMRGEISINSALRAASGALRAAIPSHRAGS"
     misc_feature    complement(20073..20088)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     misc_feature    complement(20149..20163)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.73"
                     /tool="antismash"
     misc_feature    complement(20176..20190)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.13"
                     /tool="antismash"
     misc_feature    20301..20315
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            20329..22155
                     /locus_tag="F7P10_RS44670"
                     /old_locus_tag="F7P10_26705"
     CDS             20329..22155
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014567.4"
                     /locus_tag="F7P10_RS44670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26705"
                     /product="ATP-binding protein"
                     /protein_id="WP_151013290.1"
                     /transl_table=11
                     /translation="MTFDADRSRIERAALERALRFWLVAVIVGGAAWLAAVLAAAPADR
                     ALVAAGGGGLILALCVAAALAVYFAALARRLDAHLAVAEEEDERLARRLRELVDGPLPL
                     LVGGLRDCAAPESVLADLPETPDPVLARLLRVVVEGVAAVRADADRAREETAALRADAA
                     WLTGTVLPELRTRMPERIDFVHEILDDLDRPATETFRRLAHETGLAIAHQRRWQWGVTA
                     NCALTAARMQAAVRRVLRRLYEMEFRYDETDVFWEIMDLDHQVSQLGRLADSVATMCDG
                     RSGRRWQKPIPMERIVRSAMGRCDDFRRVRYITDHDRAVCGPHAEGVIQALAELIDNAL
                     MFSLDDTPVHVYVEKEISGVVITVEDAGMGMRHTELAHAEYLVARPDDRTAWTGEAVGL
                     AVVGMLAAKHGLKVSFRPSSRGGVAAVLFVPAAIVTRPVERWPWSDDGAPGTEDEEVPS
                     DRRTAGLAGMPPIPDGRTVLAREREKERARERERERARERVRVRSGGAAAVPAPAPREP
                     FGGPSCPTENEPGEPAEPEEVVVWEGMELPKRRRGATIGPAEWALMGMRPPEPEKEDEG
                     EAFAAFMGPPGGGEADDTDQPGKPGEPDGGER"
     gene            22152..22571
                     /locus_tag="F7P10_RS26710"
                     /old_locus_tag="F7P10_26710"
     CDS             22152..22571
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630117.1"
                     /locus_tag="F7P10_RS26710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26710"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_254716033.1"
                     /transl_table=11
                     /translation="MTPETRGLVRLLDALKDKVRGVRHVLVLSRDGLRISHTDELGDDR
                     ADQLAALASGVQSLSLSASAEFGDGGGAAPGRSMVEFHGGVLLIIPAGQGAHLAVVTEP
                     NTDVGLAGRRMEELARQIRGELYAAPRRPEHDART"
ORIGIN
        1 gctgtcgtgg gcgtggccgt ggcggcgtac gggctggccg gagcgccggc tccggggcgg
       61 cgggtgagcc agcgggcgcg ggcgaccggg cggggccagg tcactcaggt cggcggagat
      121 caggttcctc gcggcgccgc ggcggccggt ggcgccggtc ggcccgccgc ggagggcggg
      181 gagcaggtgc ggcagaacgc ccgggccgac gaggacggcg cgatccggca gatcggcggc
      241 gatcaggggc gccgctcccc gtcatgaaac gccctcggcg tgactccggc gaggtgcgcc
      301 aggacgccag ggcccgcgat ggcggcgttg tccaccaggt ggccggagac cagcacgtcc
      361 atcatcacaa ccaccctgaa ggtgctgcac cgcaggtcga acgcatcgcc cgctccataa
      421 ccgatccgtt cgaccgggca cgggcgttgg gggcggtagc gaaggcggag atgaccgacc
      481 accaggagcg ggcgcaagcc ctgctggacg acgccgagcg catcgcccgc tcgattaccg
      541 acccctatag gcgggccacg gtattgggaa cggtcacgga cgtcgtcgca ggacgcgctc
      601 cggagcgggc gcaagccttg ctggacgagg ccgaacgcct caccgattcc atcaccgacg
      661 ctgacctccg ggaacagacg ttgatgttcc tggcgagagc cgccgccggg tacgctccgg
      721 ccgaggccga acgcatcgcc cgctccatcc ccggcccgac ctgcacatgg gcacttaagg
      781 gggtggcagc agtggtgatg gaaaccgctc cggccgaggc cgaacgcatc gcccgctcga
      841 tcaccaatcc aaccgctcgg gcaccggcgt tggggcaggt cgcgggggcg gtctgggaac
      901 tcgaccccca gcatgcccgg gcgctgctgg ccgaggccga acacatcgcc cgtactctcg
      961 tccccggctt cagccgggca cgggcgctga gcgagatcgc gggagcggtc gcggggcatg
     1021 cctcgtaccg tgcgcggggc ttgctgaccg aggccgagcg catcacccgc tccgacacca
     1081 agacgtttca gaagtgggcg ttgccggatg tagcggagaa cctcgctgcg ctcgacccgg
     1141 ccgaggccca gcgcatcgtc cgctccatcg ccgaccccta cgaccggaca aaggcgttgg
     1201 gaaaggtcac cgagaccatc gccgggttcg acccggccac ggccgaacgt attgcccgct
     1261 ccatccgcag gcagcacatc gaccgcttcg tcaccaagtt ctttcccaac aagtggaggg
     1321 tggcccaacc cctggagttc tacggggcac aagcgttggc ggtggtcgcg ggagccgtcc
     1381 ggaactctga cccgcagcat gccctggccc tgctgaacga agcagagcgc accgcccgct
     1441 ccatcacctt catcgacgac cgggaagagg tcctgctgca catcgtccag gccatgaccc
     1501 gtcagcagcc acggaaacga tgacctggcc cggcgggacc ccctgcgctg cctcgactcg
     1561 ccgggcagtg tccctcttga gcggcgagtc gcgacaccga gggcgctcag agccggggca
     1621 tcttgcggtg ccgcgggccg cgatgagttc ggcggggccg cccggtccat atcggtgagg
     1681 gcggcgaggg cgacggaggg agtcgggcat gccggacgag cgtgggccgg atcgggtgcg
     1741 gcgggtgctg gacgggcaca tcggggcggg gctcgcgccg ggcctcgtcg cgctcgtccg
     1801 gcggggcgcg gagacgcggg cggtcgtgct cgggtcgatg gcggcgggcg gcggcgcgcc
     1861 gatgcgccgg gacgcgctgt tccgcgtcct gtcgctcacc aagccggtga cggccgtcgc
     1921 ggcgctgtcg ctcgtcgagg acggcacgct ggcgctcgac gacccggtgg acaggtgggt
     1981 gcccgagctg gcgggtccgc gggtgctgcg ccgtccggac gggccgctgg acgacaccgt
     2041 ccccgcggca cgggccatca ccgtccgcga cctgctgacg ttccggctgg gaaccggcgc
     2101 gatgacggag ccgtgcccgc tcggggacgc gatggcggcc gcgggcgtcg ccccgggccc
     2161 ggacccgacg gagctggcgc ccggcgagtg gctcggacgg ctcggcgcgc tgccgctcgc
     2221 gtaccagccg ggcgcgcgct ggctgtacga cacgggctcg gacgtgctcg gggtgctgct
     2281 cgcccgcgcg gcggaccgtc cgctcgccga cctgttccgc gagcgggtct tcgagccgct
     2341 cgggatgcgc gacaccgggt tccacgtccc gtccggcgag gcgcaccggc tggccgcgtc
     2401 ctaccggccg ccggacgggt ccggcgtgct gacgccgcgg gacgacccgc gcgaccggcc
     2461 gcccgcgttc ccgtccggcg ccggcggcct ggtctccacc gccgacgact acgtgacctt
     2521 cttccggacg ctgctggacg gcggcggccc ggtgctgtcg cgggagtcgg tcgcggcgat
     2581 gacgaccgat cggctccgcg cggcggagaa ggcgggcgcc gggatgttcc tccagtcggg
     2641 cggctggggg ttcggcgtcg cggtcgagac tcgcgacgac ccgccggagt cccgcgccgg
     2701 acggttcggc tggatgggcg gcctcggcac gatggcgttc gccgacccgt ccgccgatct
     2761 cgtcgcggtg ctgttcacgc aggtcgagct gggttcgccg gagtccgcgc gggtgttcga
     2821 cgagttccgc gaggtcgcct acgccccggc ggagtgaccg ccgcccggcg gggcatgagg
     2881 acgggacgtc atggttccgg ccgaggggga cggcgatggg acggcagggg tggccgcggc
     2941 tgcgcgtggc cgactggcag gcgacgcgcg acacgctgca catgtgggcg cagatcgtcg
     3001 gcaaggtgcg gctggcgcac gcgccgctgg tgaaccactg gtggaacgtg acgttgtacg
     3061 tgagcccacg cgggctgacg acgtcgacga tcccctacgg caccggcgcg ttcgacgtcg
     3121 agttcgactt cgtcgggcac cggctgcggt tgcgcgggag cgacgggacg gacgaggggt
     3181 tcgcgctgga gccgatgacg gtcgcggagt tccacgaccg gacgatgcgg gccctcggcc
     3241 ggctcggcgt cgagacgcgc atccaggggc atccgaacga ggtcgatccg gcgatcccgt
     3301 tcgcggagga cgacgtgcac gcgtcctacg acgcggacgc ggcgcacctg ttctggcggc
     3361 agctgctgca ggggtcgcgg gtgctggggg agttccggtc gcggttcgtc gggaaggtca
     3421 gccccgtcca cgtgttctgg ggtgcgctgg acctcgcgtg cacgcggttc tccggccgga
     3481 ccgcgcccga ccatcccggc ggcgcgccga actgcggcga ctgggtgatg gtcgaggggt
     3541 actcgcggga gctgagcagc tgcgggttct ggccgggcgg cggcgaggag ggcgcgttct
     3601 acgcgtacgc ctacccggag ccggaggggt tcgcggcccg ttccgtgcgg ccgtcggccg
     3661 cgttctacag cgccgagaac ggccagttcc tgctgccgta cgaggcggtc gccgacgatc
     3721 ccgaccccga cgcggcgctg ctggcgttcc tccaggacac ctacgaggcc gccgccgacc
     3781 tcgccggctg ggaccgggac gtcctggagg ccgaccccgc ccgctgggcg cacaagacga
     3841 accaccgcgt gtgaaggaga cgaccgatgg tgacccgcga acagctgccc gcgcccaccg
     3901 aggggctggt gctcacgcac ttcctgaccg tccgggacgt cgcccgctcg cgcgcgttct
     3961 acgcggacgt gctcggcggc gaggtcgtcc tggcggagaa cccggcgatc gtgcgggtcg
     4021 ccaacacgtg gatcatcatg aatcccggcg gcggcccgac ccccgacaag ccggacgtca
     4081 cgctgcgggc gcccgagccg ggggacccgg tgacggcgtt catgaacgtg cgggtcgccg
     4141 acatcgccgc gttccacgcg cgcgcgacgt cgctgggcgc ccgcttcctc accgagccga
     4201 tcgaccgcaa ggccgagatc cgctgctaca tggtggatcc ggacggccgc ctcatcgagg
     4261 tcgggcaggc cacgggcatg ctgcacggcg tctacgccga cccgccggcc tgaccgttca
     4321 ggtccgccag tggccgacca gttcggcgta gagcgggctg aggtcgagca gcgtgcggtg
     4381 cgtcccgacg atcggacccg aggagtcgag cagcagcacc cggtgggccc gctcggcgga
     4441 gctgatccgg tgggcgatga cgacgagcgt ccggccccgg cccgccagcg cccgctcggc
     4501 gcgggcctcc gcggcgggcg gcaggtggca ggtcgcctcg tcgaggatga ggacgggcgc
     4561 cgccgacagg tacgcgcggg cgagcgtgac gagctggcgt tccccgtggg acagcgaccc
     4621 gccgcccggc gggacggcgg cgtcgtagcc gccgaaccgg cgcagcgtct cctccaggcc
     4681 caccgcgcgg gcggcctcgt cgagctgcgc ggtggtggcg cccggacgca ggtaggcgag
     4741 gttctcccgc agggttccgg cgaagatgta gctctcctgc gggatgagcg tcacggcgga
     4801 ccggagccgg tcccggtcga cgtcgggcag cggcacgccg ccgagcgtga cggtgccccg
     4861 ctgggggcgg acgaggtcgg tgaggacgtt cgcgagcgtc gacttgcccg tgccgctggg
     4921 gccgacgacg gccaggtggg tgcccgccgg tatgcgcagg ctcaacccgg tgaggacggg
     4981 cgcggcgcgc ggcgagtagg cgaacgtgac gcggtcgagt tcgatgtcgg acgaggcggg
     5041 gacgggcccc ggccgggcgg ggagtgcggg cgcggtgccg cccgcgcccg tctcggcgag
     5101 ccggccgagg atcaccgcga ggctgagcag cagggtgccg cccgcgtcga ccagcaggac
     5161 gatccccggc tgcagcccgg tgatgaggta gccggccgcg ccggcgacct ccccggtcgt
     5221 gagccgcccg ccgtcgatca gggacggggc cagcgcgagc agcaccagga gcggcaggtg
     5281 cacgccgagc gccagcaccg ggagccggac gagccgggac cgggcgaacg cgcgcatcgc
     5341 cgccgcctgc gcgtcgatgg acgcggcgac cgtgcgggcc gcccggtcct cggcggcgca
     5401 cgcgacgacg tcgcgcaccc ccgcgacgat cgcggcgccg gactcgccga tccgttcggc
     5461 ctgccgcacg acgtcgcggt accggcggat ctggacgccc aggaaggcgg cgaacacgcc
     5521 cacggcgacg gcgaccgaca gggcgatggc cagggcgagc ggcggggaga gcagcgcgag
     5581 cccgaccagt gcggcgatcc cggcggcgag cagctggcgg acgttgcgca gcgcggtgcc
     5641 gagcagcacc cggacggcct cggcctgctc ggcgacctgc gcgacgcccg tccccgcccc
     5701 gcccgccgtc ccgtccgcct cgcctcccgt gccgcccgtc cggtgcaggg aggcggtgac
     5761 gacgtcggtg accagggagt cgcggagcgg ctcgacggtg gtggccagcc gggggtagat
     5821 gcgccgggtc gcctcggcgc cgcacaggta gaggacggcc aggacggcga gccacgccag
     5881 gccggttccg gggcgaccgg cgaggaagcc gtggtcgacg gcgcgggcga gcagcaggcc
     5941 cccggcgagc acgggcaggc cttcgacgac ggaccacgcg gcgagcccgc gcagcgccgg
     6001 cccccgcccc cggaggtggc ggcgcagcag ccgggccgcg ggcgggaccc tcatccgccg
     6061 ggccccgggg cggtgccgaa cacggcccgg tagtcggggt cggcccacag ttcggcgtgg
     6121 ggcgcgagcg cgcggatccg gccgccgtcg agccaggcga ccaggtcggc gcgggccgcg
     6181 gtggcgggcc gccgcgccac caccaggctg gtgcggcggg ccaggagccg ctggagcgcc
     6241 cgcgtcacct tcatctccgt ggcggtgtcg aggctgctgg tggcgtcgtc gaggacgagg
     6301 acgcgggcgc cggtcagcgc cgcgcgggcg agcccgagcc gctgcagctc gccgcccgac
     6361 agcggcgccc ggtccagcgg ggtgtcgtac ccgtccggca gggcgcggac gaagtcgtcg
     6421 gcggcggccg tccgggcggc ccggcgcacc tgcgcgcggg tggcctcggg acgcgcgtag
     6481 gcgatcgtgt cgtgcacggt cgcgccgagc agcgcgggcc gctcgaacgc gtaggcgacg
     6541 gcgcggcgca gctccggcgg cgcgacggcg gtgacgggga cgccgtcgag ttcgacgcgg
     6601 ccctcctgcg ggtcgaggag ccgcccgacc agcgacacca ggacgctctt gcccgtcccg
     6661 gacgcgccga cgacggcgac cccggtcccg gcggggaccg tcagatcgag gcggtcgagg
     6721 acggtgcggt cgccgatccg gacggtgacg tcccgcaggc tgagccgtcc ggggccgtcc
     6781 ggcagcgcga ccgggcgcgg cggcggcgcg acggccggga cggtgtcgag cacctcctgc
     6841 acccgtccgg cgctgacctc gcagttcagc agcgcgacga cggtgtcgaa cagcgcggcg
     6901 gcgccgacgg ccatcgcggt gtaggaggcg gcggcgacga gcccgccggg ggtgatgtcg
     6961 ccggtggcga gccgcagccc ggcgacgccg acgaccgcga cctgcagcag cggcgccagc
     7021 agcgccagcc gccagccgac gcggccctgc acggcccagg tgcggtgccc ggcgtcgcgc
     7081 agcaggggga gcggccgcag gatccgcgcg acctcgcggt ccgcggtgcc ggaggcgcgg
     7141 atcgtccgga tcccctggtg cgcgtccagc agccgggtcg cgaccgccgc ctggtggcgc
     7201 gcgtagtccg cgaacggctc gcccgcgcgg gccacgaaca cgcgcagcac cacgacggcg
     7261 ggcggcacgc cgagcgcgaa cgccagcgcg agcgtccagt cgatcaggcc cagcgcgacc
     7321 acggcgcccg cggtcgtcgc cagggtcgcc gccaccgaca cgagctggac ggggaacgcg
     7381 gcggggccgc tcgcgctctc ggtgagccgg gagagcacgt cgccggtggg gaagcggcgg
     7441 cggccgggca ccccgagttc gaggacccgc ccgatcagcc ggtgccgcag ccacgcggtg
     7501 acgtggctgc cgcagtagga ccccgccagg tcctccccgg cgtcggccag ggcggcgacg
     7561 gcgaggacga ccgccagccc ggtcagggcg ccgcccggcg ggcggccggt gtggacggcg
     7621 tcgatcgcgc gggcgagcat gacgggcgtc gcgagggtcg ccaggacgcg cagcagcgtg
     7681 cacagcacca gcacgcccat cagggcgcgg gtgcggcgca tcgccgcgcg cagcagccgc
     7741 cgtccgccgg cgcgcagcac cgccggcgcg gggggcgcgg cgggggcttc ggtgcggggc
     7801 gcggtctcgc cgccggcggg ttcggtccgg accctgcctg tcacgcgggt cggctccctt
     7861 ccctcccggc gggcattggt tacagtgatg ggtgggtccg gtcacggatc ggccgggtca
     7921 gccgaccgat ccgtgaccgg tgtctacggg ccggggtcaa gctctattcc cgaaccgtgt
     7981 cagggtgttc ggcgtcacgc gcaggagacg ccgacgcaca cggtgttgag cagcgtcagc
     8041 agaccggcgc acgtgcacgt gccgccgagc tggatgccgt cgatctcgat cgggtcggtc
     8101 tcgggcaggt cctgcagctc cgcgaccagg tcaccgtcga agatgtccat ctgtgttcac
     8161 ctcctctcct tgctcggtac caaggtccgc cccgcgccga ggcagaagcg gaccacactc
     8221 gtccgcaggt ccgcgggcca tgcctggacg accgcggtgt ggtcgtcgtc gacttcgagg
     8281 tactcgaagc cgggcccttc ggtcctgccg agttcgagga ggcgccggcg cagcgcccgg
     8341 gactgcccga ccgggacgac ctcgtcccgg gtgccgtgcg ccacgagcag cggcgcggtg
     8401 agcgcgccgc acgcggccag gacgtcgcgc cgcgcgtccc gtccggtgcc gccgggccgg
     8461 tgcagggccg ccacccggtc ccggaccggg gcggcggcgt cgcggtagag gctcgcgggg
     8521 gaggtgaacg gcgccagcgc gacgcacgcc gcccacaggt ccgggtggcg gcacgccgcc
     8581 agcagcgcca gccacgcccc gtagctggcg ccgagcagga ccggctcccg caccctggcg
     8641 ccggtgccgc ggcggcgctc ggcgatgccg cggcccaggt ggacgacgtc cgccaggtcg
     8701 ggcccgcccc agtcgccgac gaccgcccgc aggtgccgct cgccgtagcc ggtgctgccg
     8761 cgctggttgg gggcgacgac ggcgatcccg gcggcggcga gatgctggaa gagcgggtcg
     8821 aactccagcc gccacgcggc cagcgggccg ccgtgcagcg cgaggaccac ccggtcgctc
     8881 tcgtgccagc gggcgccgcc gtagacgatc gcctcgacag gcccgtccgg gcccggcagc
     8941 tcgaccaggt cggcgcccgc ccagcgggcg gcggtgccgg ccgggcggcg cgcgagcgac
     9001 cagccggcgc ggtgcgcggt cgcgagcgtc ggcggctggt gcggcgccga gaagcgcagg
     9061 tggatccgcc cgccggtcca ggacgcgggc ggcgacagga cgccgcgcgg cccgggcacc
     9121 ggttcgacgc ggtcgtcggc cggggtgtgg atcaggaggc gggacgtcgc gccgacgtcc
     9181 tcgcagacga gcaggcgttc gccgccgccg aaggccagcg gggtgcgggc gcggccgggc
     9241 cggttgaggg acgcggggaa ccgcacccgg ccgccgccgg gcgaccacag cccgatcgcg
     9301 gggacggcgc gcccggggcc gccggtcgtc acggccagcc gccgcgcggc ccggtcgcag
     9361 gcgacgatgc ggtcgctggt cgtgtcggag accgtccaga tccggcgcca ggaccgttcg
     9421 cgcaggtcca cgacgatccc gtccgtccgg tgcccgtcgc ccgcgtggtc gagcgccagc
     9481 gtgcgcccgt cgtcgagcca cacaccgccc gacagcacgc cggggatccg gacgaccggt
     9541 tccggcgggc ccgcgccgtg cggcaggacc cagatccggg agtgccgctc gtcctcgacg
     9601 gtcacgacga ccagcgtctg gggcgagccc ggaccggcca gcgggtatcc ggcgagcatc
     9661 ggggcgatcc gccacgatcg ggcggccgcg ccgtccgggc cgtccgggcc gccgggacgc
     9721 accgcgagca cggtcccgtg gccggccggc gccccgcccg cgccggtcgc ggcccgcgcc
     9781 acgaggacgc ggccgtcgtc cagcgggatc gggcggctgg tccggtcgac ggggtcgccg
     9841 gcggtgccga cggcccggcc ggacgggacg gggccggtga ggtcccaccg ctccagcgtc
     9901 acgcggtcct ggacggtgct caggcaggtg gcccaccggc cgtcgcccga gaacgcgaag
     9961 ccgaaccggg acgggatggc gggaagggcg gggacggcgg tcacgacgcc cccctcgcgg
    10021 tggtcgcggt ggtcggcgcg gtcgcggcgg cggcgtcgac cgtccagagg cgcggcgacc
    10081 cgtaccgcag ccgcagcagg aagccgagca tcccgctgag gccgtcgccc caggtcgccg
    10141 agacctcgcc ctgctcgtcg gggaggacga gccggccgtc gcggagcgcg cgtgcggcga
    10201 cgatcgtccg ggcgagccgc caggcggccg cccggtgccg gtcgtcgccg gtcaggtcgg
    10261 ccatgtcgag caggaagtcg ccgttgcccg acaggccgtg gcactgcccg agcaccgcgc
    10321 gccaggcgtg ctcggtgacg gcgcgggcgg cgcggtcggc ggcctcgagg aagcgcgcgt
    10381 cgccggtggc ggtgccgagg cggagcagga agcttccgat gcccgacgcg ccgtggcacc
    10441 agtagggggc ggtcggcgcg tcaccggctc cggcccccca catcgcggtt ccccgctcga
    10501 cgaccgccgc gtcgaggagt tcctctccga tgcggagggc gagcgcccgg cagtcgtcgc
    10561 gtccggtcgc ctccgcgcag gcgaccagga agtagccgac gcccgcgatg ccgtgcgcga
    10621 acccgtagta ggacctgccc gcgagcttgg agtcgacgtc cgcgggggtg ctccacatca
    10681 gccggccttc gcggtcctcg accgtcccga gcagcgcgtc ggcggcggcg tccgcgcgcc
    10741 gggcgaaccg cgccgagccg gtgcgggacc acaggtgcag ggcggtcagg ccgagaccgg
    10801 cggtcccgtg ggtgatgtcg gggctggcca cggcggtcgg gagcccctcg gccacgtcgg
    10861 cggcgtcgtc gaccaggcgc tcgtcgccga gcgccaggcc cgcctccagc agcgaccacg
    10921 acacgcccgc cgtgccgaag tacaggccgg gcgggcggct cgtcccgtcc gccagccgcg
    10981 cgcggatcca ccgggccgcc gccgcgatcg cgtccggaag gcgcggatcg ccggtcagct
    11041 ccgcgtaccg caccagcgcg cccaggcagc cggcggcgcc ctgctgcagg gtgcacgggt
    11101 cgggcgcgcc gtgcacgcac gacaccggcc acagcgcgtg cggcgcgtcc gggtccatgg
    11161 aggcgaggag ttcgtcgacg atcccgccga tggcccggtc gaccgtctcc cgcggccagg
    11221 gggtctcggc gtcccggccg cgcgcccgtc gcggggcccg cgccgcgagc gcctcgcgtg
    11281 cccggtccgc cgtccagcgg tgccgcggat cgtccgccat gaggccgcgg agcatcgcgc
    11341 gcaggtgctc ggggaagtcc aggtcctgcg tccgggcggc cagccactcc tccagccgtt
    11401 cggccggcgg cctgctctcc ggggactcgt ccagcaggta gggcggggcc ccggtgaaca
    11461 ggtagcagag cgtcgccccg aggctgtagt ggtcggccga cgcgtgcggc gccgcgcccc
    11521 cgagctgctc gggtgccccg aacgcgggcg tccccgcctg gcgcgggccg tcctccccgt
    11581 cgacgaccgc gagttcgagg tcgatgagga ccggagcgcc gtccgggcgg accatgatgt
    11641 tgttggggtt gaagtcgcgg acgagcagcc cggcggcgtg cacgtcgctc atcagctcga
    11701 cgaggcggcg cgccatgtcc gtcgcggccg ggagatgccc gccccagccg gtctcgacga
    11761 tgcggtcggc cgcccactcg cgcagcggac cgccctcgat catctcctgc gcgaggaaga
    11821 ggtgcccgcc ctgcgggaac agcgcgacga gccgcggggc cagcccggtg ccggccagcc
    11881 gctccagcgc cctggcctcc gcgcgcagcc ggtcgcgggt gtcgcgcccg tccatgtcgg
    11941 cggcgacgtg cgggcgcccc tccttgatca cgaccgggtc cccggtgcgg cggtccaccg
    12001 cgcgataaac gccgcccttg ttggtatggc ggatcgcctc acgcaccgcg aagtgttcgc
    12061 cgagcattat cgctccggct tcacgtgacc gccgggtgcc gttcatgccg ttgtcgggga
    12121 agggggatgt cacccaggag ggaggcgtgt acttgccggt gcgctgatcc tcgacgggct
    12181 tcccgtccgg gtcgaggatc gtccacgtgt agaacccgtc attggtgagg cgccgctctt
    12241 cgacgaaagc gccatagcgg taatggacga ggcttccggg tgcgtacggc cgatcggaaa
    12301 ggacgcgcgg gccggccagc ccttgcgtcg cctcgtgcag ttcgcgggcg atccgcacgg
    12361 cctccgtgtc gctttcgggg tagattgtca tgaatttgcc tgaatggccg cgcgaggtgt
    12421 tgcgcgcgtt cagggcggcg acgaagtcga ccgtcgcggc gaacttgaac gccgagcgcg
    12481 cctcgcccgc gagcagcacc ggcagtgccc gtgcgagcac ctccggcgcg gacgccggcg
    12541 tggccgagac gtgcagcttc cagccctgcg ggcgtcgcgg cccctcctcg ggggcggccg
    12601 agcaccagat cccggaacgg ccgatccgcc accgtcccgg tgcggactcg atggcgcgcg
    12661 tgagggcgtc gaccagaggc gtctcttccg catccgcggc cgagacggcc gtgaagatgc
    12721 tgaatttgaa atccaccatg atgatctccg tcgcccacat tcggttggtg cctgcggcgc
    12781 agatggatcg aaatgacttc gaccatccgc tcgcctcgag cagggccaat gtaacaacga
    12841 agccgactgg aatctagtga tcacttagcg tcgccatgtc cacatcagga ctggcgtgga
    12901 tcttgactcg acttgtgatc ttgacatccg agtaatatca accggaccga aaatcggggc
    12961 cgggtgaact gggcggacct gcacttctct gcctggtcgg cgatggcgcg cccggtagtg
    13021 cccgcgcggg gccggtccgc cggtggacga aaagtggcat ccggcgagca caaaactgtc
    13081 caattagtcg gatgtggccg aaaagtgcat taaatgcggc aagtggcggt gtgcggtgtg
    13141 cggtcggcgg tcccgcgtca gcggatcatc cgggccagtt cgacgcggga gcggatgccg
    13201 agccgggtga agacgttgcg caggtggtgg tcgatggtgc gcgggctgag cagcagccgg
    13261 gcggcgatct cgcggttggt ggcgccctcg gcgacgagcc gggcgatgtg cgcctgctgc
    13321 ggggtgagct cgccgaagcc gttcgcctgc cccgggacgg tacgggacgg gacgaccgcc
    13381 gctccggaga cggacgcggg tccggcgggc gcgggcaccg cgagcggtgc gacggtctcc
    13441 ccggcggcgc gcagctcggc gcgggcctgc tcggtccagg ggccggcgtc gtagcgttcg
    13501 aagatccgca gcgcggtgcg caggtgctcg cgggcggcgc ggggcctgcg ggcgcggcgc
    13561 agccggtgcc cgtagaggag ctcggtgcgg ccctgctcga acaccgcgcc ggcggtctcg
    13621 tgcaggcgca gggcctcggt gaagtgggcg gcggcgtcgg ccggggtgtc ggcgagcagc
    13681 gcccggcagc ggtgcgcgag cgcgcggtgg acgggcgtgc cggtggcctc cgaccagcgg
    13741 cggaaggtgt cgaaggcggc cgcggcgcgg gcccggtcgc cgccgcgcgc gagcgcctcc
    13801 accaggtgcg gggcggccgc gagccgcacc cccggatgcg cgacgcccgg cccggcgggc
    13861 agccggagcc gggcgacggc gtcggacggc cggtcggcgg cgaggtcgag gcaggcgggc
    13921 gcccagccgc cgaacgcggc ggcgcggacg aggccgcggc gcccggcggc cgtggcgagc
    13981 cggtccaggt gccgttccgc cgcgccggag tcgccgtcga aggacgcggc cagggcgagg
    14041 gtcgcgagct gctcggcggc gtggccgtgc agccgggtgg cctgcgcgag gcggaggccg
    14101 tcgtgcccgg cggcgaccgg tgcgggcggg cgacccagca gcacctcgca gcgggcggcg
    14161 acggacagcg cgtacgactc cagcggaacg atcccggcgc ggcgggcggc cgcgacggcg
    14221 gcggtggcca gcgcgggcgc gagccccgcg tcgccgaggt tgagcgccgc gcgggcggcc
    14281 cacgccagcg cggccgggtc ggtgacggac gagccgtgcc gcgtcgcgct cgcgagccgg
    14341 cgggccgcct cggcgtaccg gcccgcgtgc agggcggccg tgccggtgag gtggtcgagc
    14401 atcagccggg tgcgggcctc gcgccacggc tcgtccggca gcgggagggc ggcggcgcgc
    14461 tcggcgatct cggcgtgcgc gggcacgtcc ccggcggcct cggcggcctc ggcggcccac
    14521 aggagggttt cgagggcgag ggccgcgtcg tcggcggcga accgttcggc ggcgtcccgc
    14581 agcagcggga gggcggtggc cggatccccg gaggcggcgg cgatctcgcc gcgcagccgg
    14641 tccgcgcggg cggtgcgggc gccgtcgcag cggaacgcgg cgagccgccg cagcatcgcg
    14701 cgggcgcggc gggggcgccc gctggcccac gcgtcggcgg ccgccgacag cagccggtcg
    14761 gcggcgaggg tccggtcggt ggtcagggtg gacgcgcgct gccacatccg ccacgagtcg
    14821 gcgtaccggc cggacccctg ggacacgacg gcggcgtgcg cgagctcggc ggcggccacg
    14881 tcgtcggtcc cgccggacat ggccgcgcgg tgccagatcc gcccggtgta ctgccagtcg
    14941 tggacgagta cctccgcgag cagcgcgtgc gcggcggtgc gctcggcgcg ggtggcgtcg
    15001 gcccacagcg acgaccggac gagccggtcc cggaccgtca ccgcgtccgt ctcgtaccgc
    15061 agcagccccg actcgcgggc ggcctcgacg tcggccgcgc cgatcccggc ggcgcccgcc
    15121 gcccggtcga gcgtcccggc gccgacccac tcgtcggcca cgacgagcag cacgagccgc
    15181 tgcgcgccgg cgggcagccg caggtagcgg tcgcggtgca gggcccgcag cgggctgccc
    15241 ggcggcaggg cgcgcggcgg cgcggcggcg ccggacagct gcccgggggt gagcgcggcg
    15301 gcgaggtcgc ggatggcgcg gggccgcccg tcggccaggt cgacgatcgc gtcggcgagg
    15361 gcgccgccga ccgcgtcgcc gatcgcgtcg cgcagcaccc gcaggctcgc gtcctcgtcg
    15421 agcggcccga gccgcaggtg cgggatcccg gcgagaccgg gacggtcgtc gcgggcggcg
    15481 agcagcaccg cgaccggcag gtcctggacg cggcgcgccg cgaacgccag cgcgtccagg
    15541 gacacctcgt cgagccactg gacgtcgtcg gcgcggcaga gcagcggccc gtcccgcgag
    15601 gccagcgcga gcagctcgca cagcgcggcg tagagggcga acggctcggc gtgctcccgg
    15661 ccgccgcgca cggcggcgag ggccgcgcgg tgctcgtccg ggagcagccg gatctccgcg
    15721 gccagcgggc gcagcagccg gtgcagcccg gcgtacggga cgcccgactc gcgggcgacg
    15781 ccggacgcgg tgatcgtccg gacgtccggt ccggcgcggc gcacggcctc ctccagcagc
    15841 gcggtccggc cgaggcccgc gtcggcgacg atggcgagcg cgccgccgcg gccgccgcgg
    15901 gcccggtcga gcagttcccc gatggcgtcc agttcgggta cgcgtccgtg caacgggtct
    15961 cgtccctgtg tcactgtcat gccggttctc cctgtaggcg ggggcccata ggtcagcacg
    16021 gcgtgacggg acgggtccag agcggcgttc tgttacaggg cgcgggtgca atcacgggag
    16081 ctttgcattg tgcaatggca cagtccgcgc gcacgattat ggtttcgtgt gcgttacgga
    16141 tgggaccatg atgccccccg ttcggtcctg gaggtgactc ccgatgacgg cggacgctga
    16201 cggagcgatc ctgcgcaagg ccgtcctccg cctggaggac cggcttcccg agctcgccga
    16261 ccgcctcgcc gccgagatcc tctccggcga ggacggccgc gaccgtcccg aggcggtgct
    16321 cggcgacatg tgggaggtgt gccacaccgg gctcgggcac gggttcgagg cgatcctgga
    16381 gcccggcggc ggccgcgccg acctcgactg ggcgcgccgc ctcggcgagc gccgcgccca
    16441 gcagggcgag ccgctcgagc acgtcctgcg cggctaccgg ctcgccgggc gcgtgttctg
    16501 ggaggcggtc gtggaggccg tcggccggca cgaccccgag cacatcccgg cgctcgtccg
    16561 gcaggccacc cgcacctggg acaccatcga ccagcagtcg gacgccgccg ccgacgccta
    16621 ccaccgcacc gagttcgcgc tggcccgccg cagcgaggag cgtgtccacg ccatcgtgga
    16681 cgcgctgctc gacgggcagg gcgcggacgg cgggctgctc gcgaccgcgg gcaccgtcct
    16741 cggcctgccc gtgaccggcc ggtacgccgt cgcgatgctg cgcgcggacg gcgggttcgc
    16801 cgccgacgtg gacctgcggc ccggcgaggt cggcggcatg cggttcctgt ggcggatgcg
    16861 cgcgaacgcg caggtggcgc tggtcgcgct cggtgccgcc gacctcgacg acctggtcgg
    16921 cgcgctcgaa ccctgcacgc gcgggcacgc gggcgtcagc ccggtcgccg agagcctcgc
    16981 cgacctcggc accgcccgct ggctggccga gctggcgctg cgcacctgcc acgggcccgg
    17041 cccgcaggtc gcccggctcg accggcggct cccggacgcg ctggtgctgt cgcagccgcg
    17101 cctcgcggga cggctcgggg acgtcgcgct cggcgggctc ggctccgtcg agcccgccta
    17161 ccgggaggtg ctgctcggca ccctggatac ctggctggac tgcggcggct ccgccgcccg
    17221 cgccgccgag cggctgttct gccaccgcaa caccgtgctg aaccggctcc gcaagatcga
    17281 gcagctgacc cggcggcggc tcgcccgccc gagcgacctg gtggagctgg tgctcgcgct
    17341 cagcgccgtc cggctgcacg gttccggcgc ggacccgcag gccgccccgc cggccgccgc
    17401 cccgcagggc gccgcacagc ccgccgcgtc cctcctcggc gccgcccggc cgccccgcac
    17461 ccgcatcccg tgacgcacct cgtgacacgg cccgtgacgc acctcgtgac acggcccgtg
    17521 aggcacctcg tgacacggcc cgtgaggcac cccgtggcgc ggcccgtgac gcggcccgtg
    17581 acgcaccctg caacgcgtcc gtgacgcacc ctgcgacgca gcccgtgacg cacctcgtga
    17641 cgcggcccgt gacgcatcct gcaacgcagc ctgtgacgca cgaggcaacg caccctgcga
    17701 cgcacaaggc ggggccgccc gcgcgaggtg gcgggcggcc cctgagatga ggtcgggagg
    17761 gggagcgggt tacatcgggc aggtgctgcg gtactcggag atgtccgaga accagccggt
    17821 gtcggggccg gggcagatga actgcgtgta gcgggtgtcg ttgtcgacgt agcgcttgag
    17881 ccacgcgatg ctgtacttcg cgatgtcggt gttcgaggtg ttgggtgcga agtgcgaggc
    17941 gcccgcgagc tccacgtacg ccttctccgg cgggaggctc tcgtagaacg gctcggagtg
    18001 cgagcccacc gacgcgaccg tgtcgttctc ggcgccgacg acgagggtcg gcacctggct
    18061 ctgggaccag ttcttgcgca ggttccagcc ggtcagcggg atcgcggcct tcagcgaggg
    18121 acggtcgacg gacgcctcga gcgtgccgcc gccgcccatc gagtggccca tcacggcgag
    18181 ccggttcggg tcgatgaggt cggccgcgtc gctgtcctcg accatgtagt cgagggcggc
    18241 gaggagctgg tcgccgcggc tggcgggctg gtcgaagcgg ctgttggtgt cgatcgtcat
    18301 gacgacgaag ccgcgggagg cgagccgcgg cccgtaccag gacatgctgc tctggccggc
    18361 ggtgaacccg ggcgcgatcg cgacggcgcc gaacgtctcg tccgtgtcct cggggtagta
    18421 gaccgtgcct ccgccgaagc cgctgacgaa gaggccggag acgctgtcct cgccgacgtc
    18481 gtaggagccg agcggcgcct cgatgctcga ctcggtgggg tcggggccgc gctcgtaggg
    18541 gttctcctgt gcgagggcgg tgtgggggac ggcgcagagg ccggcggcga gtgcggcgct
    18601 cgcgagcatc tgcaccgcac gtctggttgc cttcacgtcg atgacgctcc tgttccgggg
    18661 gggaggagcc cgaacggctc ccggacgcga tcattctccg caggcggacg ccgcctccac
    18721 atcggtgaaa tcacccgtcg ttcaccccgg cgcggcccag ccgttcaccg cgcctcaccg
    18781 gtgaccggcg gggccgccgc catccgcgcc ggtccgcgcg gcgcgcggtc agctcccggc
    18841 gcggtgcgac gggatcgcgg cgcggagcgc gccggacgcg gcgcgcaggg cgctgttgat
    18901 ggagatctcg ccgcgcatgc cgggcgccgc gaccatgtcg cccgcgagga acacgccgtc
    18961 cccgcggtcg atcgccggac ggtcgcgcca cgtccggccc ggcaggtcga gcgcgcccgt
    19021 ccggccccgc gcggtcgcgg tgcgcgacca ggtcgtccgg tcgccgcggc cggggacggc
    19081 ggcgtcggcg agcgcgtcga ggcggcgccg ggccccggcc ccgccctcgc cctcccgcac
    19141 gggcatgccg atctggaaga gcgtctcacc ggccgggacg gtgctcgggt cctgcatcga
    19201 gtacgactcg tggaagccgc cctcgtccag gtcgaacacg atgaacgcgt cccggcggtc
    19261 gtcgcggacg gcgaggtcca gcatcgcgta gtggccgctc tcccaggtca gggacgcgtc
    19321 gccgagcagc gcgcgggcgg acgccagttc cgtcgcgacg atcgtgggcg tgtccggcgg
    19381 cgcggtgacg cgggacccga gttcgacgcg gacgccgagt ccggcggccc gcgcggcgag
    19441 ccggtccagg accgcctgcc agccgccgat cggccagcgg acggcgggcc gcttcggcgc
    19501 gaacacgcgg ccgatcagct cccagacgaa cgcggccgac agccgtccgg tgtcggcgtc
    19561 gtaggtgacg accgagatcg cgctcgcggc ccgctcggcg gtgcgctcgc cgaaccgggc
    19621 ggacgcccac gagcggaagt cgcggtccac gggcgcccgc agcaagggcg tccgccccgc
    19681 catccgcagg aacccggcgg gcgggacgcg gcgcagccgg ccgtccgcgc ggaagaacgt
    19741 gtgcgtcatc atccgggtgt tgtacgtgcc gagggggccg gcgagcccgc gttcggtgag
    19801 ccacgaccag tgcgggccgt cggcgtagaa gacgtgcgcg ccctcgtgcg cgacgtaggg
    19861 cgcgggcgtc gcgcggcccc ggccgccgag ggtgcggtgc gcctcgtgca gggtgacgga
    19921 cgcgccgccc tccgcgcacg cgatcgccgc gacgagcccg gccaggccgc cgccgatcac
    19981 ggtgatctcg ttgctcatcg gaacctccgc cgtcgtgcgg tcgcccgggg gttcccggac
    20041 gtcgcacgaa cgacgcgtcc ggcggcgcgc ctgtgacatc tgcgtgccgg cgcgaggcgg
    20101 cgagccgggc tcgactcgtg cgtcgaggcc agtaaatggt gctgtcgtat atgtcggaca
    20161 aatgtcgcca aaaggaattc tgtcaagagt tcttccggct gattttcccg accggacctc
    20221 cacggggacc attctcctgc atcatggtgg ccacctcgca gcgagggccg ctccctgcgg
    20281 ttccgcatcg gtccggtccc atcagccgcc tcgaaaagga catgatggat gacatttgac
    20341 gcagaccgtt cccgcattga acgcgccgct ctcgaacgcg cgctccgatt ctggctcgtc
    20401 gcggtcatcg tcggcggcgc cgcctggctc gcggccgtcc tggccgccgc cccggccgac
    20461 cgcgcgctgg tcgccgcggg cggcggcggg ctgatcctgg cgctgtgcgt cgccgccgcg
    20521 ctcgccgtct acttcgccgc gctcgcccgc cgcctcgacg cccacctcgc cgtggccgag
    20581 gaggaggacg agcggctggc gcggcggctg cgcgagctgg tggacgggcc gctgccgctg
    20641 ctcgtcggcg ggctccgcga ctgcgccgcg cccgagtccg tcctcgccga cctgcccgag
    20701 acccccgacc ccgtgctcgc ccgcctgctg cgcgtcgtcg tcgagggcgt cgccgccgtc
    20761 cgcgcggacg ccgaccgcgc gcgggaggag acggccgcgc tgcgcgcgga cgccgcctgg
    20821 ctgaccggca ccgtcctgcc ggagctgcgc acccggatgc cggagcggat cgacttcgtc
    20881 cacgagatcc tggacgacct cgaccgtccc gccaccgaga cgttccggcg gctcgcccac
    20941 gagacgggcc tcgcgatcgc gcaccagcgg cgctggcagt ggggcgtcac ggcgaactgc
    21001 gcgctcaccg ccgcccgcat gcaggccgcg gtccggcgcg tgctccggcg gctgtacgag
    21061 atggagttcc gctacgacga gaccgacgtt ttctgggaga tcatggacct ggaccaccag
    21121 gtctcccagc tgggacgcct cgccgacagc gtcgcgacga tgtgcgacgg ccggtcgggg
    21181 cggcgctggc agaagccgat cccgatggag cggatcgtcc gcagcgccat gggccgctgc
    21241 gacgacttcc ggcgcgtccg ctacatcacc gaccacgacc gcgccgtctg cggcccgcac
    21301 gccgagggcg tcatccaggc gctcgccgag ctgatcgaca acgcgctgat gttctccctg
    21361 gacgacaccc ccgtgcacgt gtacgtcgag aaggagatct ccggcgtcgt catcacggtc
    21421 gaggacgcgg gcatgggcat gcggcacacc gaactggcgc acgccgagta cctggtcgcc
    21481 cgccccgacg accggacggc ctggacgggc gaggccgtcg ggctcgcggt cgtgggcatg
    21541 ctcgccgcca agcacgggct gaaggtcagc ttccggccgt cctcgcgcgg cggcgtggcg
    21601 gcggtgctgt tcgtcccggc cgcgatcgtc acccggccgg tggagcggtg gccgtggtcg
    21661 gacgacggcg cgcccggcac cgaggacgag gaggtgccga gcgaccgccg caccgccggg
    21721 ctcgcgggca tgccgccgat cccggacggc cggacggtcc tggcgcggga acgcgagaag
    21781 gagcgggcgc gggaacgcga gagggagcgg gcgcgggaac gcgtgcgcgt ccggagcggc
    21841 ggcgcggcgg ccgtccccgc gcccgcgccg cgcgagccgt tcggcgggcc gtcatgcccg
    21901 accgagaacg aaccgggcga accggccgag ccggaggagg tcgtggtgtg ggagggcatg
    21961 gagctgccca agcgccgccg cggcgccacc atcggcccgg cggaatgggc gctgatgggc
    22021 atgcggccgc cggagcccga gaaggaggac gagggggagg cgttcgccgc cttcatgggg
    22081 ccgccgggcg gcggggaggc cgacgacacc gaccagcccg gcaagcccgg cgagcccgat
    22141 ggaggggaac gttgacaccc gaaacgcgcg gcctcgtccg gctcctggac gcgctcaagg
    22201 acaaggtccg cggcgtccgg cacgtcctcg tgctgtccag ggacggcctg cggatcagcc
    22261 acaccgacga gctcggcgac gaccgggccg accagctcgc ggcgctggcg tccggggtgc
    22321 agagcctgtc gctgagcgcg tccgccgagt tcggcgacgg cggcggcgcc gcccccggcc
    22381 ggtcgatggt cgagttccac ggcggcgtcc tgctgatcat tcccgccggg cagggcgccc
    22441 acctggccgt ggtgaccgag ccgaacaccg acgtcgggct cgccggccgc cggatggagg
    22501 agctggcccg gcagatccgc ggcgagctgt acgccgcgcc gcgccgtccc gagcacgacg
    22561 cccggacatg agcacgcacc ccgccgacgg cgacgacccc gaccggctgt tcgcggtcgc
    22621 ccggggccgc gaccggacgg gcgacgaccc gcccgcgcac ggcccgtccg gcaccgcccc
    22681 cgcccccgcg cggcggcgcc ggacccggcg ggacgcgccg ccggacgtcc tcgacgtcg
//
