LOCUS       NZ_CP044407            21086 bp    DNA     circular CON 28-JUL-2024
DEFINITION  Actinomadura sp. WMMB 499 strain WMMB499 chromosome, complete
            genome.
ACCESSION   NZ_CP044407
VERSION     NZ_CP044407.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura sp. WMMB 499
  ORGANISM  Actinomadura sp. WMMB 499
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Draft genome of Actinomadura sp. WMMB499
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2019) Pharmacy, University of Wisconsin-Madison,
            777 Highland Ave., Madison, WI 53705, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. Oct-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008824145.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 05:00:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,413
            Genes (coding)                    :: 8,251
            CDSs (with protein)               :: 8,251
            Genes (RNA)                       :: 110
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 64 of 162
            Pseudo Genes (incomplete)         :: 108 of 162
            Pseudo Genes (internal stop)      :: 10 of 162
            Pseudo Genes (multiple problems)  :: 19 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:12:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 5881091
            Orig. end                         :: 5902177
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044407.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Genome not circularized.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            148..2316
                     /locus_tag="F7P10_RS26500"
                     /old_locus_tag="F7P10_26500"
     CDS             148..2316
                     /GO_function="GO:0043546 - molybdopterin cofactor binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1293: aldehyde oxidase and xanthine dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542411.1"
                     /locus_tag="F7P10_RS26500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26500"
                     /product="xanthine dehydrogenase family protein
                     molybdopterin-binding subunit"
                     /protein_id="WP_151013223.1"
                     /transl_table=11
                     /translation="MSGLVGKGVRRVDGRAKVTGAARYAADNEVPDPLHGFLVMSTVAR
                     GEVTDIDTAAALAHPGVVAVHTRMPGLVFPGFPYNRGFIPLQDSRVHHTGQPVAYVVAE
                     TLEQAQEAASLVKVRYRTEGPAVRLDDALGEAFLPPEFNGEPNEFVDGDAEAALARAEV
                     RIEQTYTSPTQHHNPIEPHTTTAVWDGDDRLTLYESAQGVIFSRLVVSRAFALEPGNVR
                     IISPYLGGGFGAKGPVYPHTLLTAAAAKLARRPVKLVLSRAQMYTSNGHRSEYRRSIRL
                     GATRRGRLTAIVDTSTAQLTRTDTHVFNTSDSTLHLYDCPNVHVRQLGVRLDLPTSSFM
                     RSPETTAHFGLETAMDELSHELGIDPVELRTRNHAAADPRTGRPHADKHLLECYRAAAK
                     AFGWERRNPEPGTTRDGDEYVGWGMATETHTYGAIPSQASVTVGVDGRATVRAATQEIG
                     TGTYTVLTQVAADALGMPLEHVTTRLGDTAFPEASLSAASATMSSVVGPVSEGARDARD
                     AVVALAVADPRSPLHGVPAGDVVAEGGHLFARGDRRRRDGYRAVMARHGRPVEVTGRLD
                     NSPGHSYGAVFLEVRVDPRLGGVRVSRVVTAHDLGRVLNRRTARGQVMGGVTWGIGFAL
                     LEHTLVDPNTARIVNPDLSGYLLPVNADAPEFEAMFVDRPARDSNALQARGFGETPGTG
                     VPAAIGNAIFHATGRRLRNVPFTRDKLL"
     gene            complement(2377..3762)
                     /locus_tag="F7P10_RS26505"
                     /old_locus_tag="F7P10_26505"
     CDS             complement(2377..3762)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621107.1"
                     /locus_tag="F7P10_RS26505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26505"
                     /product="hypothetical protein"
                     /protein_id="WP_176611667.1"
                     /transl_table=11
                     /translation="MRRRWRAATAVCTAATVAAAPAVLAPAGAAGPDRGAARDGWRLIA
                     HEGFHRPLTVDRARWQRDPHGPDSPWHVGPFDDDGEVWKTISGPEFTERLQTLDVYRKR
                     VPFGRGGWLTAEIAAVDKDKDGRPDSQPGLSTTRLPDGAKVARISEPSWDAGVLIRPTR
                     PLPPQYRVEMTLRGIDFGGKRDGSFEYDGKYNGYTEDGCKTGFPWTFKGALPGKTRCEY
                     GDVKRENGFYYMTILDHATPAPHGNPGIHYRRKVIMDGYNSNQTWSEGNGICNPETGEI
                     YSTMDGTFNGVNAIFVRGDKFRPQNNNVSNEYYFKTACGNWSGDEPFGEDGAYSDLLTG
                     AELRPELLPEASYRFAVERDATGYTIEMSGPFRHIGQATLRFHHGFVEDGRPIWHYNQT
                     PGEYDGRFDQSLTHTGPSGTYTTEHTWPAGSAYPDSFIIGDPHLNYYEGSALIDDIRLY
                     VPR"
     misc_feature    complement(3851..3868)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.03"
                     /tool="antismash"
     misc_feature    complement(3862..3877)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.39"
                     /tool="antismash"
     misc_feature    complement(3869..3884)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.07"
                     /tool="antismash"
     misc_feature    complement(3968..3983)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.64"
                     /tool="antismash"
     misc_feature    complement(3975..3990)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.38"
                     /tool="antismash"
     gene            4093..5520
                     /locus_tag="F7P10_RS26510"
                     /old_locus_tag="F7P10_26510"
     CDS             4093..5520
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015043.4"
                     /locus_tag="F7P10_RS26510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26510"
                     /product="carotenoid oxygenase family protein"
                     /protein_id="WP_151013225.1"
                     /transl_table=11
                     /translation="MAAGSTGFDPTRVAHLGGRFAPVTREVDEAELRVEGELPAELDGV
                     YLRNGPNPRFSPIGSYLFPIDGDGMVHGVWMSEGRARYRNRFVRTPAMRAEERAGRALW
                     GGVESLITPGLDEVGPDLAHTLKDLPDINVVRHGGRLLALAESDSPFRLSPDLETLGKE
                     TFGGRLPAGITAHPKIDPRTGEMAVFCYGLEAPYLTWALLGPDGEVVRGPTPVAGAEVP
                     VMIHDMALTARYLVIVLAPAYLDLAAAMRGGSFLDWRPEDGTRIALVPRDGGTVRWAHD
                     SAFWVWHTVNAHDLPTGEVVLDYVQWPGPGLGPRPAGPGGAPRGLARAVLDPAAGTVRR
                     ELLDDARVEFPRVDDRMLAGPHRRIATAAGTGRTPDLLPGEFDGLRWYEVRDGEVSAQT
                     WDANPLSVGEPVFAPVPGTTGADEGYWLTFATDRTDLSSQLLVLPGGDPAAGPVARVHI
                     PVRVPLGLHGIWLPARE"
     gene            complement(5531..6301)
                     /locus_tag="F7P10_RS26515"
                     /old_locus_tag="F7P10_26515"
     CDS             complement(5531..6301)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017608512.1"
                     /locus_tag="F7P10_RS26515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26515"
                     /product="ABC transporter permease"
                     /protein_id="WP_151013227.1"
                     /transl_table=11
                     /translation="MPEATVAIPPRTGLWATYATLLRWTIAQTGAVLPLVIVVQSLLAA
                     GVIVGFGFLVPGIDTAAARFLSTGAPTVLLVVVGLVMVPQGVAQARAGGTFTYLRALPV
                     PRPLLLLADVTVWLAVALPGVPVALVVAHLRYGFGYSFDWPLLAAASVLTAVTATAVGY
                     AVAVLLPPLLAQLATQILVFFVLLFSPITFPAARLPEWFRSVHGLLPFQPSADLLRAGL
                     LSDVHSASPRDLAVLLAWCAFGLAVSTRALTRRD"
     gene            complement(6294..7232)
                     /locus_tag="F7P10_RS26520"
                     /old_locus_tag="F7P10_26520"
     CDS             complement(6294..7232)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014908506.1"
                     /locus_tag="F7P10_RS26520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26520"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_151013229.1"
                     /transl_table=11
                     /translation="MDAVLEIDGLTRRFGPVVANDGIGLRVRAGEVVGLLGHNGAGKTT
                     LVSQLVGLLKPDAGTIRVAGADAVADPAAARRRVALQAQAQAPLDGLTPRTAIEIAGRL
                     RGLSRTGARAAADALADELDIGEWFDRRAVPGGGLSGGVRRLTAFAMAAVAPVPLVVLD
                     EPTNDVDASRRRRLWRAVRRLGDDGAGVLLVTHNVAEAERVVDELVVLDRGRVVAAGTP
                     NRLRGGDDLRLELALHPDGADPSGAAPVPVARRVRTGRRVLLTLGTSDAEAAVAWAAAL
                     RSAGRIEGYALAPATLEDAYLAATTREPADA"
     misc_feature    7251..7267
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.91"
                     /tool="antismash"
     gene            7311..7991
                     /locus_tag="F7P10_RS26525"
                     /old_locus_tag="F7P10_26525"
     CDS             7311..7991
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017608513.1"
                     /locus_tag="F7P10_RS26525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26525"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151013231.1"
                     /transl_table=11
                     /translation="MDRRPTTAAPRVRRSRAELKRETRDALVLAGLVAFTRDGYHGASL
                     EGIAGEAGYSKGAVYSNFGGKAELFLAVMDHNLEALRGADWDPFAAPEPDGADDGAAEL
                     VRGFGLATLEFIATAARDDALVDALRTRVRALLDAYGRVAAAGRPDGEDLPAGDVAMLM
                     AALEQGASVLALSGVASVEGGLLRTGLRRLVDPAGAAGEPSPGRDGRASPDVERVRRLM
                     RDMP"
     gene            complement(8240..9076)
                     /locus_tag="F7P10_RS26530"
                     /old_locus_tag="F7P10_26530"
     CDS             complement(8240..9076)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (48-147). E-value: 1e-18. Score:
                     58.6. Matches aSDomain: nrpspksdomains_F7P10_RS26530_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889258.1"
                     /locus_tag="F7P10_RS26530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26530"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_151013233.1"
                     /transl_table=11
                     /translation="MHTIANTQQAEAWNGWEGAAWADGAARYDAMMGGFNEPLLAAAAI
                     GADDRVLDVGCGTGQTALLAARRAARVLGADISAPMLARARADASARGVAGVRFVQADA
                     EVHPFEEHAFDVAISRGGVMFFADPVAAFANIARALRPGGRLAFVAPRAGGPDSPYTRA
                     TAALAPLMRAPSPASRGMGSLVDPDRIRGVLGEAGLLEVRVRPVEAMMDYGRDAADAAD
                     FILGQGPVRFNLKDIDRDAAARVREDLRAGLRAYETPDGVRIRGSVWLVTAVRPGG"
     aSDomain        complement(8636..8932)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS26530_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.00E-18"
                     /label="F7P10_RS26530_oMT.1"
                     /locus_tag="F7P10_RS26530"
                     /protein_end="147"
                     /protein_start="48"
                     /score="58.6"
                     /tool="antismash"
                     /translation="DRVLDVGCGTGQTALLAARRAARVLGADISAPMLARARADASARG
                     VAGVRFVQADAEVHPFEEHAFDVAISRGGVMFFADPVAAFANIARALRPGGRLA"
     misc_feature    9061..9075
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.3"
                     /tool="antismash"
     misc_feature    9131..9140
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.13"
                     /tool="antismash"
     gene            9183..9827
                     /locus_tag="F7P10_RS26535"
                     /old_locus_tag="F7P10_26535"
     CDS             9183..9827
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017584694.1"
                     /locus_tag="F7P10_RS26535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26535"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151013235.1"
                     /transl_table=11
                     /translation="MNDVKRTDKRTDGRAERSRRTREKIVEAARELFVAQGYGATSLRE
                     VADAAGVAVQTVYFVFHNKRTLFKDVVDAAIAGDAEPVATMDRAWFRAACAAPTAAEQL
                     RAHVRGTREILGRVAPIMPMIAAAAATDPEIAAQWPGGPDPRYTVQRAAAGALAGKPDA
                     DPGVDVETAADLLFGLLSPELYLIFVRDRGWSPDAWEEWAGAALIAQLCRA"
     gene            10001..11086
                     /locus_tag="F7P10_RS26540"
                     /old_locus_tag="F7P10_26540"
     CDS             10001..11086
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /GO_function="GO:0010333 - terpene synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0042214 - terpene metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009077431.1"
                     /locus_tag="F7P10_RS26540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26540"
                     /product="family 2 encapsulin nanocompartment cargo protein
                     terpene cyclase"
                     /protein_id="WP_151013237.1"
                     /sec_met_domain="T1TS (E-value: 1.2e-49, bitscore: 168.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGVGQSAEGRVPWRMPGPVGLGTSGTAVPRTAPPYTLRTWGDGSA
                     PALYVPAVERVDAILAADVEARLRAWAAALGFSDDELDAMGSAGFGRLAMLTHPDTDDP
                     DALLTAAKLNASWWAADDYYADDTALGAVPELLPPRLALAMSAMDGPPEAGDFTPPLDA
                     ALGDDLVLRMLRSATAHLAARASTAVVQRVCYSTFAMFVSWTAYAAWRETDRHPPAWEY
                     LAARQHDSFYTSMTLIDAVGGYELPAELYYQQRVREALFRAGTASVLVNDLFSVAKDAA
                     DEKPVCNMVLLVAADRECSVEEATAAVVDLHNDFVRGFQRAQNELAVVPSPQLQWFLRG
                     AQAWMGGGFEWHATNERYRDA"
     gene            11165..12043
                     /locus_tag="F7P10_RS26545"
                     /old_locus_tag="F7P10_26545"
     CDS             11165..12043
                     /EC_number="2.1.1.255"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0008757 - S-adenosylmethionine-dependent
                     methyltransferase activity [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (98-197). E-value: 3.5e-15. Score:
                     46.9. Matches aSDomain: nrpspksdomains_F7P10_RS26545_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013153643.1"
                     /locus_tag="F7P10_RS26545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26545"
                     /product="geranyl diphosphate 2-C-methyltransferase"
                     /protein_id="WP_151013239.1"
                     /transl_table=11
                     /translation="MSTTTTTTATTATANVLKSPYQRSVADYWNQERNPVNLLLGAVDG
                     IYHHHYGIGEPDWSVLEGPQETREQRTIEELHRLETAQAGFLLDQLGPVPADGRLLDAG
                     CGRGGTSLMANLRFGCRVEGISISEEQVRFANEQAEQRGVADSVRFSFRNMLSTGFETG
                     SFDGIWNNESTMYVDLNDLFAEHSRLLRRGGRYVTITGCYNDVYGLPSRAVSEINSHYI
                     CDIHPRSAYFKAMAAHDLVPIATVDLTEATIPYWRMRARSPHLATGIEKAFLEAYTGGS
                     FHYLLIAADRV"
     aSDomain        11459..11755
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS26545_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="3.50E-15"
                     /label="F7P10_RS26545_oMT.1"
                     /locus_tag="F7P10_RS26545"
                     /protein_end="197"
                     /protein_start="98"
                     /score="46.9"
                     /tool="antismash"
                     /translation="RLLDAGCGRGGTSLMANLRFGCRVEGISISEEQVRFANEQAEQRG
                     VADSVRFSFRNMLSTGFETGSFDGIWNNESTMYVDLNDLFAEHSRLLRRGGRYV"
     gene            12056..13483
                     /locus_tag="F7P10_RS26550"
                     /old_locus_tag="F7P10_26550"
     CDS             12056..13483
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017623772.1"
                     /locus_tag="F7P10_RS26550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26550"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_151013240.1"
                     /transl_table=11
                     /translation="MTSVPQDVRPGPLSLSTDAARLLATTTKTRPQMQAISSRWLLRKL
                     PWVEVSGGTYRVNRRRVTTARQRLLAFRWGASGVHVAPDSLAGFPALHGLAPDVLTELA
                     GRFTARDVEPGDVLAAEGAPVTEVLAVARGRVERIGTARYGGTAMLGVLTDGRHAGGDL
                     LAADSADAADAGESGPVWRETLRAATPATVLALPREALAELGDASPALRAHLAAFRAAA
                     SEPANRRGEAEIRLASGHGGEPPLPDTFADYDARPLEIELAVAQTVLNVHTRVADLYNG
                     PMDQAEEQLRLVVEALRERQEWELVNNPEFGLLHQADDAQRIASWSGPPTPDDMDDLLA
                     MRRGTRLFLAHPKAIAAFFRECTRRGVYPDQIVEGEKRLLGWRGVPIYPCGKIPVTSDH
                     TSSIMAMRTGEDDSGVVGLHQTGLPGEYEPSLNVRFMGVTEAAITRYLVSAYFNATILV
                     PDALGVLEGVEIAAPRA"
     gene            13616..14074
                     /locus_tag="F7P10_RS26555"
                     /old_locus_tag="F7P10_26555"
     CDS             13616..14074
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012891732.1"
                     /locus_tag="F7P10_RS26555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26555"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_151013242.1"
                     /transl_table=11
                     /translation="MAANEKAGGSGGPGRVSRWMQHKANGRVTRKIRRGQGRAMGMDVL
                     ILNTVGKRSGEARETPVAWFEDGADGRLVVASGGGSRHPDWYVNLMAHPDRATIEVAGA
                     GAEPVTPHRLEGADRADAWRRIAEAQPRIAKYQRKSDREYPVVRLTPR"
     misc_feature    complement(14221..14234)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.66"
                     /tool="antismash"
     gene            14358..16034
                     /locus_tag="F7P10_RS26560"
                     /old_locus_tag="F7P10_26560"
     CDS             14358..16034
                     /NRPS_PKS="Domain: oMT (347-455). E-value: 7.8e-21. Score:
                     65.5. Matches aSDomain: nrpspksdomains_F7P10_RS26560_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017621373.1"
                     /locus_tag="F7P10_RS26560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26560"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_254716031.1"
                     /transl_table=11
                     /translation="MSYWKSYRGTRAQGGRPIQRQDFGENPTEVRDTNHYEKEYVQGFV
                     EKWDELIDWRRRYESEGTFFIDQLKARGVKRVLDVATGTGFHSVRLVQEGFDTVSADGS
                     QEMLRKAFENGFTYGQYVLKVVQADWRYLNRDVHGEFDAIICLGNSFTHLFSERDRRKA
                     LAEFYALLKHDGVLIIDQRNYDSILDNGFSSTHSYYYCGEEVTAEPEYVDEGLARFRYR
                     FPDGSDYALNMFPLRKDYMRRLMREVGFQRVDTFGDFQKSYHEDDPDFFIHVAEKMYRE
                     DDSGGSSYSTAVNTAREYYNSEDADAFYHSVWGGQHIHVGVYEDGDTIDAASGRTVERM
                     ASGLELTPDVHVLDVGAGFGGSARHLARTYGCKVTCLNLSEVENARNRAANKDQGLDEL
                     IDVVDGSFEELPFNDNAFHVVWSQDALLHGGDRIRALEEIVRVLKPGGDFVFTDPMAAD
                     DCPRDALRPILDRLHLDTMGSPGFYRRELARLGLSVRFDDLTEHLTTHYGRVLRETEER
                     EAEMSGQISAGYLEHMKTGLRNWVDGGANGRLKWGIIRCKN"
     aSDomain        15399..15722
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS26560_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="7.80E-21"
                     /label="F7P10_RS26560_oMT.1"
                     /locus_tag="F7P10_RS26560"
                     /protein_end="455"
                     /protein_start="347"
                     /score="65.5"
                     /tool="antismash"
                     /translation="PDVHVLDVGAGFGGSARHLARTYGCKVTCLNLSEVENARNRAANK
                     DQGLDELIDVVDGSFEELPFNDNAFHVVWSQDALLHGGDRIRALEEIVRVLKPGGDFVF
                     TDPM"
     gene            complement(16271..16918)
                     /locus_tag="F7P10_RS26565"
                     /old_locus_tag="F7P10_26565"
     CDS             complement(16271..16918)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025791.4"
                     /locus_tag="F7P10_RS26565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26565"
                     /product="SUKH-4 family immunity protein"
                     /protein_id="WP_176611668.1"
                     /transl_table=11
                     /translation="MTTQDLVDAFGDEDVRRFGDGELPTEVVHTVTRRFLTTVGIPTDL
                     KSSFLSLAKFEPLPETHARESAAGHWTWDLPDDAKKCFVLGGFFGGDVALDGADGKVFF
                     IPDGDVLPQPMHSGIDALAYFMYALQRDTHYYSQEYAEQIDADPDDERDADDVLMETAV
                     RLARELMEVDRTPFTVGELPPYEIGSGEDPFTGDFAGPWTGAFMDISAGEWD"
     misc_feature    16934..16951
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(17122..17136)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 19.59"
                     /tool="antismash"
     misc_feature    complement(17137..17153)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.14"
                     /tool="antismash"
     gene            17281..17886
                     /locus_tag="F7P10_RS26570"
                     /old_locus_tag="F7P10_26570"
     CDS             17281..17886
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653117.1"
                     /locus_tag="F7P10_RS26570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26570"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151013246.1"
                     /transl_table=11
                     /translation="MSADVRFTVTRTLSKDQQARRERLIDAAWTLAVEGGYPAVTMHDV
                     ADRAGVARATVYRYFATKDHLLTEVAATWAHRVTDDIDALAVGDTPVERLTALLERIVR
                     VAADNVMLTSAIIQAVTADDSSVDDSRDVVFLFLRDRLSAAIGDPVPQREDVEVVLGHV
                     LLAALVSVASLHRPADEVAEIVRTSGRLVLAGALAGGV"
     misc_feature    complement(17300..17320)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.3"
                     /tool="antismash"
     gene            18087..19301
                     /locus_tag="F7P10_RS26575"
                     /old_locus_tag="F7P10_26575"
     CDS             18087..19301
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653116.1"
                     /locus_tag="F7P10_RS26575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26575"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_151013248.1"
                     /transl_table=11
                     /translation="MTTTLEEHSPLKPWAGVPSELSEIFRPHLDGLAEEMIEEILAGIP
                     EYSRPQDEEYARLVRMAVEGALRQFVDLIMDPNSSWEQVGAVYREIGWAEAREGRSLDI
                     LQTSMRLGARVAWRRLAAESEQYNVSRHTLASLAEAIFAFLDEIARAATEGYTKARAQE
                     AGELEHRRRRLLDLLLAEPPASAQAVADLARLAQWRVPRTVAAVVLYERGRQPFSHPSL
                     PPDVLSDVNRREPCLLVPDPEGPGRGRMLESGLRNWVAAMGPTVRTEDAAKSLRWAREA
                     LPLARRGILPSDRLIRCADHMPMLVVFKDEELVRAVADLRLAPLRTVRPRHRERLVRTL
                     LSCLQNGFNATEVATRLHVHPQTVRYRLHQLEELFGDRLYEPEARLELEMALTVWLTAP
                     SPSSD"
     gene            19333..19968
                     /locus_tag="F7P10_RS26580"
                     /old_locus_tag="F7P10_26580"
     CDS             19333..19968
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543285.1"
                     /locus_tag="F7P10_RS26580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_26580"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151013250.1"
                     /transl_table=11
                     /translation="MTSDSGRERILDVATRLFAALGYDGTSTRLIAEAAGLNIATVAYH
                     VGGKRDLYLAVMERAHQAERTALEDAVRDLRAAGTGGDAGADAGAAAALGLVDRYVDFC
                     AANPAVPALWMHRWLSDAADVAHLESLYVRPLMDLVVDAVRELAGDGVDVEYAVWTVIW
                     ATHGFARGGVLDADGRRRGMDDPRELARFRAHLHRLVTAALDLPGGPR"
ORIGIN
        1 gcggggccgg cggctgaccg ggcggacggt cgccgaggcg gggcgcgtcc tggtccggga
       61 cgcccgcccg cgcgaaggga acgggttcaa ggtcgagctc gtgcggcggg cgctggagag
      121 cgtcctcgac gacctgggag gcgttcgatg agcgggctgg tcggcaaggg cgtgcggcgg
      181 gtggacggcc gcgcgaaggt caccggcgcg gcgcgctacg ccgcggacaa cgaagttccc
      241 gacccgctgc acggcttcct ggtgatgagc accgtcgccc gcggcgaggt cacggacatc
      301 gacacggcgg cggcgctggc gcatcccggg gttgttgcgg tccacacccg catgccgggg
      361 ctggtgttcc cgggcttccc gtacaaccgg ggcttcatcc cgctgcagga ctcgcgggtc
      421 caccacaccg ggcagccggt cgcctacgtc gtggccgaga ccctcgagca ggcgcaggag
      481 gccgcgagcc tggtgaaggt ccgctaccgg acggaggggc ccgccgtgcg gctggacgac
      541 gccctcggcg aggccttcct cccgcccgag ttcaacgggg aacccaacga gttcgtcgac
      601 ggtgacgccg aagcggccct cgcgcgggcc gaggtgcgga tcgagcagac ctacaccagc
      661 ccgacgcagc atcacaaccc gatcgaaccg cacaccacca ccgcggtctg ggacggcgac
      721 gacaggctga cgctgtacga gagcgcgcag ggcgtgatct tctcccggct ggtcgtgtcg
      781 agggccttcg cgctggaacc ggggaacgtc cggatcatct cgccctacct gggcgggggt
      841 ttcggcgcca agggcccggt ctatccgcac acgctgctca ccgcggcggc ggcgaagctc
      901 gcccggcggc ccgtgaagct ggtcctgtcg cgggcgcaga tgtacacgtc caacggccac
      961 cgctcggagt accggcggag catccggctc ggcgccaccc ggcgcggccg gctcaccgcc
     1021 atcgtcgaca cctcgacggc gcagctgacc cgcaccgaca cgcacgtctt caacacgagc
     1081 gactcgacgc tccacctgta cgactgcccg aacgtccacg tccggcagct cggcgtgcgg
     1141 ctggacctgc ccacgtccag cttcatgcgc tcaccggaga ccaccgcgca cttcggcctc
     1201 gagaccgcca tggacgagct gagccacgag ctcggcatcg acccggtgga actgcggacg
     1261 cgcaaccacg ccgccgccga cccccggacg ggacggccgc acgccgacaa gcacctgctg
     1321 gagtgctacc gggcggcggc caaggcgttc ggctgggaac gccgcaaccc cgagccgggg
     1381 acgaccaggg acggcgacga gtacgtcggc tggggcatgg ccaccgaaac ccacacttac
     1441 ggcgcgatcc cctcccaggc gagcgtcacg gtcggcgtgg acgggcgggc gaccgtgcgg
     1501 gccgccaccc aggagatcgg caccggcacc tacaccgtgc tcacccaggt cgccgccgac
     1561 gcgctcggca tgcccctgga gcatgtcacg acgcggctcg gcgacaccgc cttccccgag
     1621 gcgtccctgt ccgcggcgtc ggccaccatg tccagcgtgg tcgggccggt ctccgagggc
     1681 gcgcgggacg cgcgggacgc cgtggtcgcg ctcgccgtcg ccgatccccg gtccccgctg
     1741 cacggcgtgc ccgccgggga cgtcgtggcc gagggcggtc acctcttcgc ccgcggcgac
     1801 cgccgccgca gggacggcta ccgcgccgtc atggcccgcc acggtcgccc cgtcgaggtc
     1861 accggacgcc tggacaacag ccccgggcac agctacggcg cggtgttcct ggaggtccgg
     1921 gtcgacccgc ggctcggcgg cgtgcgcgtg agccgggtcg tgaccgccca cgacctggga
     1981 cgggtcctca accggcgcac cgcgcgcggc caggtcatgg gcggcgtgac gtggggcatc
     2041 ggcttcgcgc tgctcgagca cacgctggtg gacccgaaca cggcccggat cgtcaatccc
     2101 gacctgtccg gatacctgct gccggtgaac gcggacgcgc ccgagttcga ggccatgttc
     2161 gtggaccggc cggcccggga cagcaacgcc ctccaggccc gcggcttcgg cgagacgcca
     2221 ggaaccgggg tgcccgcggc catcggcaac gcgatcttcc acgccaccgg ccggcggctg
     2281 cggaacgtcc ccttcacgcg ggacaagctg ctctgatcga ccccggccac cggggcggcc
     2341 acggccggca gggccgcccc cggtgcgcct ccggggttac ctcgggacgt agaggcggat
     2401 gtcgtcgatg agtgccgagc cctcgtagta gttgaggtgc gggtcgccga tgatgaacga
     2461 gtcggggtag gccgagcccg cgggccaggt gtgctcggtg gtgtaggtgc cggacgggcc
     2521 ggtgtgggtg aggctctggt cgaaccggcc gtcgtactcg ccgggcgtct ggttgtagtg
     2581 ccagatcggg cggccgtcct cgacgaagcc gtggtggaag cgcagcgtcg cctgcccgat
     2641 gtgccggaac ggaccgctca tctcgatggt gtagccggtg gcgtcgcgtt cgaccgcgaa
     2701 ccggtaactc gcctcgggca gcagttccgg gcggagttcg gcaccggtca ggaggtcgct
     2761 gtaggcgccg tcctcgccga acggttcgtc gcccgaccag ttcccgcacg ccgtcttgaa
     2821 gtagtactcg ttgctgacgt tgttgttctg cggacggaac ttgtcgccgc gcacgaagat
     2881 ggcgttcacg ccgttgaacg tgccgtccat cgtgctgtag atctcgccgg tctcgggatt
     2941 gcagatcccg ttgccctccg accaggtctg gttgctgttg tagccgtcca tgatgacctt
     3001 gcggcggtaa tggatgccgg ggttgccgtg gggtgcgggc gtggcgtgat cgaggatggt
     3061 catgtagtag aagccgttct cacgcttgac gtcgccgtat tcacagcgcg tcttgccggg
     3121 cagcgcgccc ttgaacgtcc acgggaaccc ggtcttgcag ccgtcctcgg tatagccgtt
     3181 gtacttgccg tcgtactcga agctcccgtc gcgctttccg ccgaagtcga tgccgcgcaa
     3241 cgtcatctct acgcggtact gcgggggcag cggccgggtc ggccggatca gcacgccggc
     3301 gtcccagctc ggctcggaga tccgcgcgac cttcgcgccg tccgggagcc gggtggtgga
     3361 cagtcccggc tgcgagtcgg gccggccgtc cttgtccttg tcgacggcgg cgatctcggc
     3421 ggtgagccac ccgccgcggc cgaacggcac ccgcttgcgg tacacgtcga gcgtctggag
     3481 ccgttcggtg aactcggggc cgctgatcgt cttccagacc tcgccgtcgt cgtcgaacgg
     3541 gccgacgtgc cacgggctgt ccggcccgtg cggatcacgc tgccacctgg cacggtccac
     3601 cgtgagcggg cggtggaacc cctcgtgggc gatcagccgc cagccgtccc gcgcggctcc
     3661 ccggtcgggg ccggccgcgc cggcgggggc gaggacggcg ggcgcggcgg cgacggtcgc
     3721 ggcggtgcac accgccgtgg ccgctctcca gcgtcgtctc atgacctgct tccttcctcc
     3781 agcgcccccg gaggccgcgt cccgtgaggg acggccgctg tatgccgacg tgcgtgaccg
     3841 aaacatcgac ggaacaccgg cctgacaaag tggtaaagac ctcttgggtc tctcggtggg
     3901 atgaggggtt ctttcctggc cgggacacgc gacttcggtc ttgatcgacg ctcaccatac
     3961 gaaccgtccg aacaattggt caataccaat ctcccgatgc gtcgcccgcg cctcgctccg
     4021 tcccgagtcg ggatgaggcg cggacgggcg ggcatggggg agcgcagggc accggtgtcg
     4081 ggggaggttg ccatggccgc gggttccacc gggttcgatc cgactcgagt cgcgcatctc
     4141 ggcgggcggt tcgcgcccgt caccagggag gtggacgagg cggagctgag ggtggagggc
     4201 gagctgcccg ccgagctgga cggcgtgtac ctgcgcaacg gccccaatcc gcggttcagc
     4261 cccatcggct cgtacctgtt cccgatcgac ggggacggca tggtgcacgg cgtgtggatg
     4321 agcgagggac gggcccggta ccgcaaccgt ttcgtgcgga cgcccgcgat gcgcgcggag
     4381 gagagggcgg gacgagcgct gtggggcggc gtcgagtcgc tgatcactcc ggggctcgac
     4441 gaggtcgggc cggacctggc gcacacgttg aaggacctgc cggacatcaa cgtggtgcgg
     4501 cacggcgggc ggctcctggc gctcgccgag tccgacagcc cgttccggct gagcccggac
     4561 ctggagacgc tcggcaagga gaccttcggg gggcggctgc ccgccgggat caccgcccat
     4621 ccgaagatcg acccgcgcac cggggagatg gccgttttct gctacggcct ggaggcgccc
     4681 tacctcacct gggcgctgct cggcccggac ggcgaggtcg tgcgggggcc gacgcccgtg
     4741 gcgggcgcgg aggtcccggt gatgatccac gacatggcgc tgaccgcgcg ctacctcgtc
     4801 atcgtcctcg ccccggccta cctggacctg gcggcggcga tgcggggcgg ctcgttcctg
     4861 gactggcggc ccgaggacgg gacgcggatc gcgctggtgc cgcgcgacgg ggggacggtg
     4921 cgctgggcgc acgactccgc gttctgggtc tggcacacgg tgaacgccca cgacctgccc
     4981 acgggagagg tcgtcctgga ctacgtccag tggccgggcc ccgggctcgg cccgcgcccc
     5041 gccggaccgg gcggggcgcc gcgcgggctc gcgcgggccg tcctggaccc ggccgccggg
     5101 accgtccggc gcgaactgct ggacgacgcg cgcgtggagt tcccccgcgt ggacgaccgg
     5161 atgctcgcgg ggccgcaccg ccggatcgcc acggccgccg ggaccggacg gacgccggac
     5221 ctgctgcccg gcgagttcga cgggctgcgc tggtacgagg tgcgggacgg ggaggtgtcc
     5281 gcgcagacgt gggacgcgaa cccgctctcg gtcggcgagc ccgtgttcgc gcccgtcccc
     5341 ggcaccaccg gcgcggacga ggggtactgg ctcaccttcg ccaccgaccg taccgacctg
     5401 agcagccagc tgctcgtcct gcccggaggg gacccggccg ccgggccggt cgcgcgcgtc
     5461 cacatccccg tgcgcgtgcc gctggggctg cacggaatct ggctgcccgc gcgggagtga
     5521 cgcctccgga tcagtcgcgg cgggtcaggg cgcgggtgct gaccgccagg ccgaacgcgc
     5581 accaggcaag caggacggcg aggtcccgcg ggctcgcgct gtggacgtcc gacagcaggc
     5641 ccgcgcggag caggtcggcg gacggctgga acgggagcag tccgtggacg gaccggaacc
     5701 actcgggcag gcgcgcggcc ggaaaggtga tcggggagaa cagcagcacg aagaacacga
     5761 ggatctgggt ggcgagctgg gcgagcagcg ggggcagcag gacggcgacc gcgtagccga
     5821 ccgcggtcgc cgtgacggcg gtcaggacgg acgcggccgc caggagcggc cagtcgaagg
     5881 agtagccgaa gccgtaccgg aggtgggcga cgaccagcgc gacggggacg cccggcaggg
     5941 cgaccgccag ccacacggtc acgtcggcca gcaggaggag ggggcgcggc accggcaggg
     6001 cgcgcaggta ggtgaaggtg cccccggcgc gcgcctgcgc gacgccctgg gggaccatca
     6061 cgaggccgac gaccacgagc aggacggtgg gcgcgcccgt cgacaggaac cgggcggccg
     6121 cggtgtcgat gccggggacg aggaagccga acccgacgat gacgcccgcg gccagaaggg
     6181 actggacgac gatgacgagc ggcagtaccg cgccggtctg ggcgatcgtc cagcgcagca
     6241 gggtcgcgta ggtcgcccag agcccggtgc gcggcgggat cgcgacggtc gcctcaggca
     6301 tcggcgggct cccgggtggt cgcggcgagg taggcgtcct cgagggtggc gggggccagc
     6361 gcgtagccct cgatccgtcc ggcggagcgg agggcggcgg cccaggcgac ggcggcttcg
     6421 gcgtcggacg tgccgagggt cagcagcacc cggcggccgg tgcggacgcg gcgggcgacc
     6481 gggaccgggg cggcgccgga cgggtcggcg ccgtccgggt gcagggcgag ttcgagccgc
     6541 aggtcgtcgc ccccgcggag ccggttcggc gttccggcgg cgacgacgcg gccgcggtcg
     6601 aggacgacga gttcgtccac gacgcgttcg gcctcggcga cgttgtgggt gacgagcagg
     6661 actccggcgc cgtcgtcgcc gagccggcgg acggcccgcc acagccggcg ccgccgcgag
     6721 gcgtcgacgt cgttggtggg ttcgtcgagg acgacgagcg ggacgggcgc gacggcggcc
     6781 atcgcgaacg cggtcagccg gcgcacgccg cctgagaggc cgccgcccgg tacggcccgc
     6841 cggtcgaacc actcgccgat gtcgagttcg tcggcgagcg cgtccgcggc ggcccgcgcg
     6901 ccggtgcggg acagcccgcg cagccgtccg gcgatctcga tggccgtccg gggcgtcagg
     6961 ccgtcgagcg gggcctgtgc ctgggcctgg agcgccacgc ggcggcgggc ggccgccggg
     7021 tcggcgaccg cgtccgcacc ggccacccgg atcgtcccgg cgtcgggctt gagcagcccc
     7081 acgagctgcg agacgagggt cgtcttgccc gcgccgttgt ggccgagcag cccgacgacc
     7141 tcgcccgcgc ggacgcgcag gccgatcccg tcgttggcga cgaccgggcc gaaccgtctc
     7201 gtgaggccgt cgatctccag taccgcgtcc atcgtcactc cgaaataccg ttggtattga
     7261 agtaccgacg gtatcaggat gccagtggta cgtgaactac gatgtgcggc atggatcgac
     7321 gccccacgac ggccgcaccg cgggtgcggc ggagccgcgc cgagctgaag cgggagacgc
     7381 gggacgcgct cgtcctggcg gggctcgtgg cgttcacccg cgacggctac cacggagcga
     7441 gcctggaggg gatcgcgggc gaggccgggt actccaaggg cgcggtctac tcgaacttcg
     7501 gcggcaaggc cgagctgttc ctcgcggtga tggaccacaa cctggaggcg ctgcggggcg
     7561 ccgactggga cccgttcgcg gcgccggagc cggacggcgc cgacgacggc gcggcggagc
     7621 tggtgcgcgg gttcgggctc gcgacgctgg agttcatcgc gacggccgcg cgcgacgacg
     7681 cgctcgtcga cgcgctgcgc acgcgggtcc gggcgctgct cgacgcctac gggcgggtcg
     7741 cggccgcggg ccgtccggac ggcgaggacc tcccggccgg cgacgtcgcg atgctcatgg
     7801 ccgcgctcga gcagggggcg tcggtgctcg cgctcagcgg cgtcgcgtcc gtcgagggcg
     7861 ggctgctgcg caccggcctg cggcggctcg tggacccggc gggcgcggcg ggggagccgt
     7921 caccgggacg ggacggccgc gcgtcgccgg acgtcgagcg tgtgcggcgc ctgatgcgcg
     7981 acatgccctg accgccccgg cctcggacgt ccggtcctgc cgtcccggac ggcggtaacc
     8041 ggcgcggtga ccccggggcg tggggcggct caggggggag ggcttcggcc ggcgcgtgcc
     8101 acccggcgcg gtggccgccg tcctcgcgca tgcctggggt cacgccgatg gggccgagat
     8161 cggtgtcacc gtcgcgcgcc ttcccgccga tgttcctcgc ccgacgaccg cgacgctgca
     8221 ttctcgacct tgcttgaagt caccctccgg ggcggacggc ggtcacgagc catacggaac
     8281 cgcggatccg gactccgtcc ggggtctcgt aggcccggag tcccgcccgg agatcctcgc
     8341 ggacgcgcgc ggcggcgtcc cggtcgatgt ccttgaggtt gaagcggacc gggccctggc
     8401 cgaggatgaa gtccgccgcg tcggcggcgt cgcggccgta gtccatcatc gcctcgaccg
     8461 gacggacgcg cacctcgagc agccccgcct cgccgagcac cccgcggata cggtcggggt
     8521 cgaccagcga ccccatgccc cgggacgcgg gcgaaggcgc gcgcatcagc ggtgcgagcg
     8581 cggcggtggc gcgggtgtag gggctgtcgg ggccgcccgc ccgcggggcg acgaacgcca
     8641 ggcggccgcc gggccggagc gcgcgggcga tgttggcgaa cgcggccacg gggtcggcga
     8701 agaacatgac gccgccgcgg ctgatggcga cgtcgaaggc gtgctcctcg aaggggtgga
     8761 cctcggcgtc cgcctgcacg aaccggacgc cggcgacgcc ccgcgcggac gcgtcggcgc
     8821 gggcgcgggc cagcatcggc gcggagatgt ccgcgccgag cacccgtgcg gcccggcgcg
     8881 cggccagcag ggccgtctgg cccgtgccgc acccgacgtc caggacgcgg tcgtccgcgc
     8941 cgatcgcggc ggcggccagg agcggctcgt tgaagccgcc catcatcgcg tcgtaccggg
     9001 cggcgccgtc cgcccaggcc gcgccctccc agccgttcca cgcttccgcc tgctgggtgt
     9061 tggcgatcgt gtgcatcggt ctcctccggt ctccgggtgc gacggctccc gggcggtgcg
     9121 cccgtccggc catcttttta gagtcgaact ttagtgttcg actctagata taagctccca
     9181 ccatgaacga cgtcaagcgg acggacaagc ggacggacgg gcgcgccgag cgctcgcgcc
     9241 gcactcggga gaagatcgtc gaggcggcgc gggagctgtt cgtcgcgcag gggtacgggg
     9301 cgacgagcct gcgggaggtc gccgacgccg cgggcgtggc cgtccagacc gtctacttcg
     9361 tcttccacaa caagcgcacg ctgttcaagg acgtcgtcga cgcggccatc gccggtgacg
     9421 ccgagcccgt ggccaccatg gaccgcgcat ggttccgcgc cgcgtgcgcc gcgcccacgg
     9481 cggcggagca gttgcgcgcg cacgtgcgcg gcacccggga gatcctgggg cgggtcgcgc
     9541 cgatcatgcc gatgatcgcg gccgcggcgg ccaccgaccc ggagatcgcc gcgcagtggc
     9601 cgggtggccc cgatccgcgg tacaccgtgc agcgggcggc ggccggcgcg ctcgcgggca
     9661 agcccgacgc cgatcccggc gtcgacgtcg agacggccgc ggacctgctg ttcggcctcc
     9721 tcagcccgga gctgtacctg atcttcgtgc gggatcgcgg ctggtcgccg gacgcgtggg
     9781 aggaatgggc cggtgcggcc ctgatcgccc agctctgccg agcgtagttc cccggcgcca
     9841 cgtgcgtcgc acggttacca cgtgtcactc tcggtgtcca tggccgtgtc cggtcgcggt
     9901 cccttccttt cgcgatagtt acttatcgtg tgcgctcatg tgcgaacggt ggcatcctct
     9961 tggtggaatc gaggacgtcg cgagatcttc gggaggccgc atgggcgtgg ggcagtcggc
    10021 ggaaggacgc gttccgtggc ggatgccggg gccggtcggg ctcggcacca gcgggaccgc
    10081 ggtgccgagg accgccccgc cctacaccct ccggacctgg ggcgacggct cggcgccggc
    10141 gctgtacgtc ccggccgtcg aacgcgtcga cgcgatcctg gccgccgacg tcgaggcccg
    10201 gctgcgtgcc tgggcggccg ccctcgggtt cagcgacgac gagctggacg cgatgggctc
    10261 cgcgggcttc gggcgcctcg cgatgctcac ccatccggac accgacgacc ccgacgcgct
    10321 gctcacggcc gcgaagctga acgcgagctg gtgggccgcc gacgactact acgccgacga
    10381 caccgcgctg ggcgccgtcc ccgaactgct gccgccccgg ctggccctgg ccatgtccgc
    10441 gatggacggg ccgccggagg cgggcgactt cacgcccccc ttggacgcgg ccctcggcga
    10501 cgacctcgtg ctgcggatgc tgcggtcggc caccgcccat ctcgcggccc gcgcgagcac
    10561 ggccgtggtg cagcgcgtct gctactcgac gttcgcgatg ttcgtgagct ggacggccta
    10621 cgccgcctgg cgcgagaccg accggcaccc gcccgcgtgg gagtacctcg cggcccgcca
    10681 gcacgacagc ttctacacct cgatgacgct gatcgacgcc gtcggcggct acgagctgcc
    10741 cgccgagctg tactaccagc agcgggtccg cgaggcgctc ttccgggcgg gcaccgcgtc
    10801 cgtcctggtg aacgacctgt tctcggtggc gaaggacgcg gccgacgaga agccggtctg
    10861 caacatggtc ctgctcgtgg ccgccgaccg ggagtgctcc gtcgaggagg cgaccgcggc
    10921 cgtggtcgac ctgcacaacg acttcgtccg cggcttccag cgggcccaga acgaactggc
    10981 ggtcgtgccg tccccgcagc tccagtggtt cctgcgcggc gcgcaggcct ggatgggcgg
    11041 gggcttcgaa tggcacgcca ccaacgagcg ctaccgggac gcctgaccgc ccgtccggcc
    11101 ccgtccggcc cccgtccgaa accctgccga acctgcctga cccatgccac gaggaggaac
    11161 ccccatgtcc acgaccacca cgaccaccgc gaccaccgcg acggcgaacg tgctcaagag
    11221 cccctaccag cgttcggtcg ccgactactg gaaccaggag cgcaacccgg tgaacctgct
    11281 gctgggggcg gtggacggca tctaccacca ccactacggc atcggcgagc cggactggtc
    11341 ggtgctggag gggccgcagg agacccgcga gcagcggacg atcgaggagc tgcaccggct
    11401 ggagaccgcg caggccggct tcctgctcga ccagctcggc cccgtcccgg cggacgggcg
    11461 gctgctggac gccgggtgcg ggcggggcgg cacgagcctg atggcgaacc tgcggttcgg
    11521 ctgccgggtg gagggcatct cgatctccga ggagcaggtc aggttcgcaa atgagcaggc
    11581 tgagcagcgg ggcgtcgccg actccgtgcg gttctccttc cgcaacatgc tctcgaccgg
    11641 gttcgagacg ggctccttcg acggcatctg gaacaacgag tccaccatgt acgtcgacct
    11701 gaacgacctg ttcgccgagc acagccggct gctcaggcgc ggtggccgct acgtcacgat
    11761 caccggctgc tacaacgacg tctacgggct gccgtcgcgg gccgtcagcg agatcaactc
    11821 gcactacatc tgcgacatcc acccgcgcag cgcgtacttc aaggcgatgg ccgcgcacga
    11881 cctcgtcccg atcgcgaccg tggacctcac cgaggcgacc atcccctact ggcggatgcg
    11941 cgcccgctcg ccgcacctgg ccaccggcat tgagaaggcc ttcctcgagg cctacaccgg
    12001 cgggagcttc cactacctgc tgatcgccgc cgaccgcgtc tgacgaagga aggccatgac
    12061 ctccgttccg caggacgtcc gtccgggccc gctcagcctg tcgacggacg cggcccgcct
    12121 gctcgcgacc acgaccaaga cccggcccca gatgcaggcc atctcctcgc ggtggctgct
    12181 gcgcaagctc ccgtgggtcg aggtgtccgg cgggacctac cgggtcaacc gacggcgcgt
    12241 cacgaccgcc cggcagcggc tgctcgcgtt ccggtggggg gcgtccggcg tccacgtggc
    12301 accggactcc ctcgccgggt tccccgccct gcacgggctc gccccggacg tcctcaccga
    12361 gctggccgga cggttcaccg cccgcgacgt cgagcccggg gacgtcctcg ccgccgaggg
    12421 cgccccggtg acggaggtgc tggccgtcgc gcgcggacgg gtggagcgca tcggcaccgc
    12481 ccggtacggc gggacggcga tgctcggggt cctcaccgac gggcggcacg cgggcggcga
    12541 cctgctcgcg gcggactccg cggacgcggc ggacgccggg gagtccgggc ccgtctggcg
    12601 ggagaccctg cgggccgcca cgcccgcgac cgtcctggcg ctgccgcgcg aggcgctcgc
    12661 cgagctgggc gacgcgagcc cggcgctgcg cgcgcacctc gcggcgttcc gcgcggcggc
    12721 gtccgaaccg gcgaaccggc ggggggaggc ggagatccgg ctcgcgtccg ggcacggggg
    12781 cgagccgccg ctgcccgaca ccttcgccga ctacgacgcc cggccgctgg agatcgagct
    12841 ggccgtcgcg cagaccgtcc tgaacgtcca cacgcgggtc gcggacctgt acaacgggcc
    12901 gatggaccag gcggaggagc agctgcgcct ggtggtggag gcgctgcggg agcggcagga
    12961 gtgggagctg gtcaacaacc cggagttcgg gctgctgcac caggccgacg acgcgcagcg
    13021 gatcgcgtcc tggtccggtc cgccgacacc ggacgacatg gacgacctgc tggcgatgcg
    13081 gcgcggcacc cggctgttcc tcgcccaccc gaaggcgatc gccgcgttct tccgggagtg
    13141 cacccggcgg ggcgtctacc cggaccagat cgtcgagggg gagaagcggc tgctcggctg
    13201 gcggggcgtc ccgatctacc cgtgcggcaa gatcccggtg acgtccgacc acacgtcgtc
    13261 gatcatggcc atgcggacgg gcgaggacga ctcgggcgtg gtcggcctgc accagacggg
    13321 cctgcccggg gagtacgagc cgtcgctgaa cgtccggttc atgggcgtca ccgaggcggc
    13381 gatcacccgc tacctggtga gcgcgtactt caacgcgacg atcctcgtcc cggacgccct
    13441 gggcgtcctg gagggcgtgg agatcgcggc gccgcgcgcg tgaccggccc ggtacgtccc
    13501 ccgtcttccc aggtcggggg cgtaccggat cggtcaggaa tcgagaagtg cgcatgaccg
    13561 gcccccgcct accgttacgg ccatggacgt gcggccgagc ggagggagcg gatcgatggc
    13621 ggcgaacgag aaggcgggcg ggagcggcgg gccggggcgg gtgtcgcggt ggatgcagca
    13681 caaggcgaac ggccgggtca cgcggaagat ccgtcgcggg cagggccggg cgatgggcat
    13741 ggacgtgctg atcctgaaca cggtcggcaa gcggagcggg gaggcccggg agacgcccgt
    13801 ggcgtggttc gaggacggcg cggacggccg gctggtcgtc gcgtcgggcg gcgggagccg
    13861 gcacccggac tggtacgtca acctcatggc gcaccccgac cgggcgacga tcgaggtggc
    13921 cggcgccggc gccgagccgg tgacgccgca ccggctggag ggcgccgacc gcgcggacgc
    13981 gtggcggcgc atcgcggagg cgcagccgcg gatcgcgaag taccagcgca agagcgaccg
    14041 ggagtacccg gtggtgcgcc tcaccccgcg ctgagcctcc accgcgaccc gcggccggat
    14101 gcggccacgc gggggtgtgc ggggaaagcg gcggatggcc ggagacggcc atgtggggga
    14161 ggggacgggc ggccggaggc ggccccgaat ccgggccgat gttgcgctgg tcacacagtg
    14221 tgttagcgaa aagtaccccg ggaacccctt atagaaagct gtgcgcaggg ctaacgtcgt
    14281 cctgtatgtc acgttcgtgg ctgactgtca cagaatgtgg tgattagcat gccgaacgtg
    14341 acgacggtac gtgttcagtg agctactgga agtcatatcg ggggacgcgc gcacagggag
    14401 gcagaccgat tcagcggcaa gatttcggcg aaaatccgac tgaggtccgc gacaccaacc
    14461 actacgagaa ggagtacgtc caaggcttcg tcgagaagtg ggacgagctc atcgactgga
    14521 ggaggcgcta cgagagcgaa ggcaccttct tcatcgacca gctgaaggca cgcggcgtca
    14581 agcgagtact cgacgtcgcg accggcaccg ggttccactc ggtgcggctc gtgcaggaag
    14641 gcttcgacac cgtcagcgcg gacggcagtc aggagatgct gcgcaaggcg ttcgagaacg
    14701 ggttcaccta cgggcagtac gtcctcaagg tggtgcaggc cgactggcgc tacctgaacc
    14761 gcgacgtgca cggcgagttc gacgccatca tctgcctggg gaattcgttc acccatctgt
    14821 tctcggaacg tgacaggcgc aaggcgctcg cggaattcta cgcgctgctg aagcacgacg
    14881 gcgtgctcat catcgaccag cgcaactacg actcgatcct ggacaacggg ttcagcagca
    14941 cgcactcgta ctactactgc ggcgaggagg tcacggccga gcccgaatac gtggacgagg
    15001 ggctggcgcg gttccggtac cggttcccgg acggaagcga ctacgccctc aacatgttcc
    15061 cgctgcgcaa ggactacatg cggcggctca tgcgggaggt cggcttccag cgggtcgaca
    15121 ccttcgggga cttccagaag tcctaccacg aggacgatcc cgacttcttc attcacgtgg
    15181 cggagaaaat gtatcgggaa gacgactccg gcggctcctc ctactcgacg gcggtgaaca
    15241 ccgcccgcga gtactacaac tccgaggacg ccgacgcgtt ctaccactcc gtctggggcg
    15301 ggcagcacat ccacgtcggc gtctacgagg acggcgacac gatcgacgcg gcgagcggcc
    15361 ggacggtcga gcggatggcg tcgggcctgg aactgacacc ggacgtgcac gtgctggacg
    15421 tcggcgccgg gttcggcgga tcggcccggc acctcgcccg cacgtacggc tgcaaggtca
    15481 cgtgcctgaa cctgagcgag gtcgagaacg cccgcaaccg cgcggcgaac aaggaccagg
    15541 gactcgacga gctgatcgac gtggtcgacg gctcgttcga ggaactgccg ttcaacgaca
    15601 acgcgttcca cgtcgtgtgg tcgcaggacg ccctgctgca cggcggcgac cgcatccggg
    15661 cactggagga gatcgtccgg gtgctcaagc cgggcggcga cttcgtcttc accgacccga
    15721 tggccgccga cgactgcccg cgggacgcgc tgcgtcccat cctcgaccgg ctgcacctcg
    15781 acacgatggg ctcgcccggc ttctaccgcc gggaactggc ccgcctcggg ctgagcgtgc
    15841 ggttcgacga cctcaccgag cacctcacca cgcactacgg gcgggtgctg cgggagaccg
    15901 aggagcggga ggcggagatg tccgggcaga tcagcgcggg ctatctcgag cacatgaaga
    15961 ccggcctgcg gaactgggtc gacggcggcg cgaacggccg cctgaagtgg gggatcatcc
    16021 gctgcaagaa ctgaccggct gcaagaagtg accggttgca agaactgacc ggttcggtct
    16081 ctccgggacg gcccgggcgg gacgggcgcg agcgcccccc gcccgggccg tcccgttcgc
    16141 gtgccgccgg tgcgcgccgc gtccggacgg gcgggacccc ggcacccgtg ccgccgttcg
    16201 cgcaggttcc cgttcatccc cgttcgactc gtccgtgttc gactcgtccg tcccggctcg
    16261 cgcgcgggcg tcagtcccac tcgccggcgg agatgtccat gaacgccccg gtccacgggc
    16321 cggcgaagtc gccggtgaag gggtcctcgc cgctgccgat ctcgtacggc ggcagttctc
    16381 cgacggtgaa cggcgtccgg tcgacctcca tgagctcccg ggcgagccgc accgccgtct
    16441 ccatgaggac gtcgtccgcg tcccgctcgt catcgggatc ggcgtcgatc tgctccgcgt
    16501 actcctggct gtagtaatgc gtgtcgcgct ggagcgcgta catgaaatac gcgagggcgt
    16561 cgattccgct gtgcatcggc tgcgggagga cgtcgccgtc gggaatgaag aagacctttc
    16621 cgtcggcgcc gtcgagtgcg acgtcaccgc cgaagaagcc gccgagcacg aaacacttct
    16681 tcgcgtcgtc cggaaggtcc catgtccagt ggccggccgc gctctcgcgg gcgtgcgtct
    16741 cgggtagcgg ctcgaacttc gcgaggctga ggaaactgct cttgaggtcg gtcgggatgc
    16801 cgaccgtggt gaggaagcgg cgcgtgacgg tgtggacgac ctcggtcggg agttcgccgt
    16861 cgccgaaccg gcggacgtcc tcgtcgccga acgcatcgac gagatcctgc gtcgtcaact
    16921 ccggaaccat gtgcatcccc tcgtgcggac cccgagccgg tgaagctgtc ggtggggtcg
    16981 gtacgaacgc gtgcggccgt ccgcggggga gcggcccgcg catgcgcttc cgtggcccgg
    17041 cggcgagacg ggccgcggat cggttcgcgg gaccccgggc atccggcgat cccgtcgcgc
    17101 cgatgccgtc ttacggggcg atgaagatga tatcgaatgt tcatgtataa cgggattttc
    17161 cctgatggag agtgcttttc tgggcggcgg gcgggtccgg cccgggccgg gcgagcgggg
    17221 gaagatcgcg atacgggacg atgtgcggga caatgggcgc gccgacagcg aggaggcgtt
    17281 gtgagcgcgg atgtgcggtt caccgtcacg cggacgctga gcaaggatca gcaggcgcgg
    17341 cgggagcggc tgatcgacgc ggcgtggacc ctggcggtgg agggcggcta cccggccgtc
    17401 accatgcacg acgtcgcgga ccgggcgggc gtcgcccgcg ccaccgtgta ccgctacttc
    17461 gccaccaagg accacctgct caccgaggtc gccgcgacct gggcgcaccg ggtcaccgac
    17521 gacatcgacg cgctcgcggt cggggacacg ccggtcgagc ggctcaccgc gctgctggag
    17581 cggatcgtgc gggtcgcggc cgacaacgtc atgctcactt cggcgatcat ccaggcggtc
    17641 accgcggacg actccagcgt cgacgactcc cgcgacgtgg tgttcctgtt cctgcgggac
    17701 cggctgtcgg cggcgatcgg cgatccggtg ccgcagcgcg aggacgtcga ggtcgtcctc
    17761 gggcacgtgc tgctcgccgc gctggtcagc gtcgcgtcgc tgcaccggcc ggccgacgag
    17821 gtcgcggaga tcgtccggac gtccggacgg ctcgtcctcg cgggcgccct cgccggaggc
    17881 gtgtgagcga ccgcgccgga ggcgtgtgag cgaccgcgcc ggaggcgagt agcagccgga
    17941 gtgaatcggg cggaacgggc gaaccgattg tcatcgagat gacaaccgcc ctggcgcatt
    18001 gcgtcttcga tggtaaagcc ggtcccgtgc gcggtcggta gcttccagaa cgccccctgg
    18061 acaccgtagg ggcgggaggt ggaaccgtga ccacgaccct ggaggagcat tcgccgctca
    18121 agccgtgggc gggcgtgccg agcgagctgt cggagatctt ccggccgcac ctggacgggc
    18181 tggccgagga gatgatcgag gagatcctgg ccgggatccc cgagtactcc cgcccgcagg
    18241 acgaggagta cgcgcggctc gtccggatgg cggtggaggg cgcgctgcgc cagttcgtcg
    18301 acctgatcat ggacccgaac agctcgtggg agcaggtcgg ggcggtctac cgggagatcg
    18361 gctgggcgga ggcccgggag ggccgcagcc tcgacatcct gcagacgtcg atgcggctgg
    18421 gcgcgcgcgt cgcgtggcgg cggctggcgg cggagtccga gcagtacaac gtgtcgcggc
    18481 acacgctcgc ctccctcgcc gaggcgatct tcgctttcct ggacgagatc gcccgcgcgg
    18541 ccaccgaggg gtacaccaag gcccgcgcgc aggaggcggg cgagctggag caccgccgcc
    18601 gccggctcct cgacctgctg ctggccgaac cgcccgcgtc ggcccaggcc gtcgcggacc
    18661 tggcgcggct ggcgcagtgg cgggtgccgc ggacggtcgc cgcggtcgtc ctgtacgagc
    18721 gggggcggca gccgttctcg cacccgtcgc tgcccccgga cgtcctgtcc gacgtgaacc
    18781 gccgcgagcc gtgcctgctg gtgcccgatc ccgaggggcc gggccggggc cggatgctgg
    18841 agtccgggct gcggaactgg gtggccgcga tggggccgac ggtccgcacc gaggacgccg
    18901 cgaagtcgct gcgctgggcg cgggaggcgc tgccgctcgc gcgccgcggc atcctgccgt
    18961 ccgaccggct gatccggtgc gccgaccaca tgccgatgct ggtggtcttc aaggacgagg
    19021 aactggtgcg ggcggtcgcg gacctgcggc tcgcgccgct gcggaccgtc cggccccggc
    19081 accgcgagcg gctggtgcgc accctgctgt cgtgcctgca gaacgggttc aacgccaccg
    19141 aggtcgccac ccgcctgcac gtgcacccgc agaccgtccg gtaccggctg caccagctcg
    19201 aggagctgtt cggcgatcgc ctgtacgagc cggaggcgcg gctggagctg gagatggcgc
    19261 tgaccgtctg gctcaccgcc ccctctccat caagcgattg accaaatccc ggcgggcggc
    19321 taccgtcgcc gcatgaccag cgactccggc cgggagcgca tcctcgacgt cgccacccgg
    19381 ctgttcgccg ccctcggcta cgacggcacc tccacccggc tcatcgccga ggccgccggg
    19441 ctcaacatcg ccacggtcgc ctaccacgtc ggcggcaagc gcgacctgta cctcgccgtc
    19501 atggaacgcg cccaccaggc cgaacgcacc gcgctcgagg acgccgtccg cgacctgcgc
    19561 gccgcgggca cgggcgggga cgcgggcgcg gacgcgggcg ccgccgcggc gctcgggctc
    19621 gtcgaccggt acgtcgactt ctgcgccgcc aacccggccg tcccggcgct gtggatgcac
    19681 cgctggctgt cggacgccgc cgacgtcgcc cacctggaga gcctctacgt ccggccgctg
    19741 atggacctgg tcgtggacgc cgtccgggaa ctcgccggcg acggcgtgga cgtcgagtac
    19801 gccgtctgga ccgtcatctg ggccacgcac gggttcgcgc gcggcggcgt cctcgacgcg
    19861 gacgggcggc gccgcggcat ggacgacccc cgggaactcg cccggttccg cgcccacctg
    19921 caccgtctcg tcaccgccgc cctggacctc cccggcggtc cgcgatgacc gccccggcca
    19981 ccacgaccgc cccggtcccg ctgacacgcg cgcgcctgct cggctacggc gtcggctcgg
    20041 tcggcaccgg cgtgttcaac gccgtccccg ggctgctcct gctctactac ctcaccgacg
    20101 tgctcggcgt cggcgcggcc gtcgccggtg ccgtcctcgt gctgcccaag gcctgggacg
    20161 tcctgctcaa cccggtcgtg ggcgccgcca gcgaccgcga ggccgtccgg accggccgcc
    20221 gcacccgcct cctgctgctc ggcgcctgca cgctgcccgt cctgttcgcc gcgatgttcg
    20281 ccgtcccggt cgactcgccc ggattcgccg ccgcctgggc ggggctggcg ttcctcctcg
    20341 ccgccagcgc gttcgcctgc ttccaggtcc cctacgtcgc gctgcccgcc gagatctccg
    20401 ccgaccccgc cgaacgcggc cgcgcgatgg cctggcgggt cgtctgcctc accgccggga
    20461 tcctcgtcgc gggcggtgtc gcgcccgccg tcaccgacgc cgccgggggc ggccgcgccg
    20521 ggcacgcgct gatgggcgcc gccgtcgggg ccgtcattgc cgccgcgacg atcggcagcg
    20581 ccctcgccac ccgctggatc ccgtcccgcc ccggacccca cgcgctcggc ctgcgcgccg
    20641 cgctccgcac cgcgcgcggc aaccggccgt tcttcgccct gctcggcgcg tacgtcctga
    20701 acacgctcgc cgtcgcgatc atgctcgcgg gcgcccccta cgtcgcgacc taccggctgg
    20761 acgactacgc cctcacgtcc gcgatgttcg tctgcatggt cgcaccgagc gcgttcgccg
    20821 tcccgttctg gcgggtgctc gcccgcaggt tcggtgccgt gtcctgctac gtcgccgcgg
    20881 tcgtcgtgtt cgccgtggtg gtcgccgcgc tgttcccggt ggtcacctcg atgccggccg
    20941 ttctcgcgct cagcgcgggc gtcggtgtct gctacgccgc gacccagtac cttccgctcg
    21001 ccctgctgcc cgagaccgtc cacgccgact ccggacgcac cgggcacgcc cagtccggcg
    21061 cgttcaccgg cctgtggacg gccgcc
//
