LOCUS       NZ_CP044407            22571 bp    DNA     circular CON 28-JUL-2024
DEFINITION  Actinomadura sp. WMMB 499 strain WMMB499 chromosome, complete
            genome.
ACCESSION   NZ_CP044407
VERSION     NZ_CP044407.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura sp. WMMB 499
  ORGANISM  Actinomadura sp. WMMB 499
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Draft genome of Actinomadura sp. WMMB499
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2019) Pharmacy, University of Wisconsin-Madison,
            777 Highland Ave., Madison, WI 53705, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. Oct-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008824145.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 05:00:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,413
            Genes (coding)                    :: 8,251
            CDSs (with protein)               :: 8,251
            Genes (RNA)                       :: 110
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 64 of 162
            Pseudo Genes (incomplete)         :: 108 of 162
            Pseudo Genes (internal stop)      :: 10 of 162
            Pseudo Genes (multiple problems)  :: 19 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:12:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3390062
            Orig. end                         :: 3412633
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044407.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Genome not circularized.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22571
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="10"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22571
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22571
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12571](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12571
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    complement(1817..1831)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     gene            complement(2521..3228)
                     /locus_tag="F7P10_RS14765"
                     /old_locus_tag="F7P10_14765"
     CDS             complement(2521..3228)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025205.4"
                     /locus_tag="F7P10_RS14765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14765"
                     /product="DUF4194 domain-containing protein"
                     /protein_id="WP_151009868.1"
                     /transl_table=11
                     /translation="MSEPDVRDEPDGTDGAGSPGAGGSAVEAAGFIDPVAMEDDPAELF
                     AGDAGTLDVDVRRLLVRLLQRRFLLAEKSPAQWRTLLENHQIIESRLHDLFVRLVVDHE
                     RGIAYKQQVRSAELDVPILLKDDPYNRAETLVLVHLRTVFQRERGTGETSARVDIEELE
                     QTVLTYFDPDDHNLARGQHEIRKAVERLVKEGLLAEESAGRYRITPLVEVVLSTERLTE
                     LNQWLRERNEAAP"
     gene            complement(3221..4744)
                     /locus_tag="F7P10_RS14770"
                     /old_locus_tag="F7P10_14770"
     CDS             complement(3221..4744)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF023283.4"
                     /locus_tag="F7P10_RS14770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14770"
                     /product="DUF3375 domain-containing protein"
                     /protein_id="WP_151009869.1"
                     /transl_table=11
                     /translation="MGTRGVEGAYQGALRAFQNPMLDLLHRTYAPFVVTVLAMMFTPER
                     PTVVVADAHAEIADALDQLRAAGYGSEDDQPLPAGNARDLCRQWVQAGWLVRQVSDDVE
                     VYRLSAHGVGALEVAGRVGGARTRVSESRVRTLLEAVERLAQDADPDVMARMARLQTEI
                     DQRRRELERLERGGAVETVDDDQLLEAAENVLHLARELPADFARVAESIKAMQRDVVAD
                     LRQDVRPTGEVLREYLERGRQIMDATPEGRAFAGALRLIGDPAQIEDLWNLLRTVLRHG
                     FTGLMAEPQRRELAEIARRIEQGVKEVLTAQRQASHVITTQVRDHDPMRDRQVDELLRD
                     VMSGLHAWVPGSRRGTAVDPLRRLPVADVGQLRQTMSDPRPPQPPTPLREWDETEDVPT
                     ADTRAWGGPQYADLHAHLAAFADGADGTDGVDVAAAFRAADERIRRPVDLLGLLEIAHD
                     LGMADTAEVAVVETVRPDRSRRRLAFGGVLAANPARPRAAAETPGSDDE"
     gene            4989..6155
                     /locus_tag="F7P10_RS14775"
                     /old_locus_tag="F7P10_14775"
     CDS             4989..6155
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024945.4"
                     /locus_tag="F7P10_RS14775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14775"
                     /product="CdaR family transcriptional regulator"
                     /protein_id="WP_151009870.1"
                     /transl_table=11
                     /translation="MEINGQGTTLDGTLRSYVPEVAAEVTVRIRREVPALGAARYLDSF
                     VESLIGHFLDLLDESGPPSDEILGRAREAGVREAAEGRGPDVLPAAARLGAGIAIARLS
                     EHAERLGLRVEISAVGKIAQMVFAYTDRIAEAVIAGHGGSGAHAVGEDEKRRRELLDLL
                     LTPCPGAAEIKAAARSAGWPMPRTVAVIALGAGGPRPVLPPDALFGLHLDEPCLLLPDP
                     DGPARRRQVAAGLRGRTAAIGPTVGVADAARSLRWAYRTLSLVRSGRITAEGSRPVRSA
                     DHLPRLMTSWGADLVELVAADRLAPLDAVRPSVRRELEVTLLALLECHFRAIVTAARLH
                     VHPQTVRYRLRRLEALFGEELYEPRNQLDMHLLLYARTRDRVGAARAD"
     gene            6211..8475
                     /locus_tag="F7P10_RS14780"
                     /old_locus_tag="F7P10_14780"
     CDS             6211..8475
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1041:
                     transcriptional regulator, SARP family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024793.4"
                     /locus_tag="F7P10_RS14780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14780"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_151009871.1"
                     /transl_table=11
                     /translation="MDLPRATTSYVGRRCETAEVRAALAAGRLVTLTGPGGVGKTRLAA
                     ATAAQVAGGFADGAVFVDLTELRDGTLLPDLVATRLGLHNRSGQPARRLVLSHLRERAL
                     LLLLDNCEHVVDEAAEFAAAVLAGCGGVAVLGTGRQSLGVAGERVLRVPSLAVPAEDVA
                     ASPAELARYDAVRLLVDRASSIVPGFELTAGNGAAVVRICRHLDGLPLAIELAAARMRS
                     LSPQQVADRLTRRLPLRTSSPRTAPERQRTLRATIEWSFSLCSPAEQALWSRASVFAGT
                     FDLTAAERVCAGPGLAAEEVLDAVDGLLDKSVLIREDHGDIVRYRMLETLREHGRELLD
                     QAGQRSAVRLRHRDWIDRLTAAADADWVSREQLSWIVRLRLEQANLRAALEWSLTEPGE
                     AGAVLRIASRLDEYWTFFGHSQECRQWLDRALAIAPSDHPDRPRALAICALHGVWHLDL
                     DAAERRLAEADRFAGPRDDLLRALLGYVRALAAQIRTDTCAADLAAEAAAVFRAHGDVR
                     RELHPLWIFGVSTGYRKGDVAEGRRALRRMLELCEAHGETRYRAMAQFGLAYLEVERGD
                     VEPAEELARESLRNLMKIGAGSGTAYLLDNLAWIADRKGEHVKAATLFGAAATLWRAIG
                     SAPEIAVSGPHRAHRASTLAALGEEHFGRAFAAGRGMTGAEAARYALGAAEPGEGARPG
                     ALTGRQWEIAGLVAEGLTNRDIAAKLVISQRTADTHVRNILDKLGFRKRAQVAVWFTEQ
                     R"
     misc_feature    8705..8718
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     misc_feature    complement(9409..9423)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.1"
                     /tool="antismash"
     misc_feature    9410..9423
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 15.36"
                     /tool="antismash"
     misc_feature    9411..9424
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.67"
                     /tool="antismash"
     misc_feature    complement(9411..9425)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.46"
                     /tool="antismash"
     misc_feature    complement(9412..9425)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.3"
                     /tool="antismash"
     misc_feature    complement(9573..9586)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.61"
                     /tool="antismash"
     misc_feature    complement(9600..9613)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 18.22"
                     /tool="antismash"
     gene            9664..9867
                     /locus_tag="F7P10_RS14785"
                     /old_locus_tag="F7P10_14785"
     CDS             9664..9867
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7P10_RS14785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7P10_14785"
                     /product="hypothetical protein"
                     /protein_id="WP_151009872.1"
                     /transl_table=11
                     /translation="MNALLVGPRDAGPSTADLDIGFFDSDEEVAAHGPQACAPTCNTGM
                     TFVCDGDSAHTCTYGQTFVCDS"
     gene            10001..12571
                     /gene="lanL"
                     /locus_tag="F7P10_RS14790"
                     /old_locus_tag="F7P10_14790"
     CDS             10001..12571
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="F7P10_RS14790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14790"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_151009873.1"
                     /sec_met_domain="Pkinase (E-value: 1.7e-17, bitscore: 62.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 6e-18, bitscore: 63.7,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVGEFGWRTRAGRVWVHCDPPSVSLPEQGWKIHVSARPATLPETL
                     RVVVPLLVRRGCAFKVVNGREALAELNAPDDRVSSVGKAITAYPSPDLFRELAVELAEA
                     LRGFAAPVVRSDRRVHPEAPVYYRYGPFAARYRVSLNGQPELVVTGPDGEEYPGAAGRF
                     FDCPPWERDPLSADQGPPPDADEVTPVGKGAPVGDGDPGVVLGGRWRLREGVRNSSRGR
                     IFRGRDVVTGREVVVKEARAYIGGETADSDCRANLRSERRVLAALDGVTGVPQVLDHFR
                     HGEDEFLVLSSMGRRNLADDVATSGIYPDRPGERDLSVLARELLVLLDAVHERGVVVRD
                     LSPKNVVLDEAGGCHLIDFELARLDGRQRPGYSRGYCSPEQLRGEPGTVADDHFAVGMT
                     LFYAATGIDPVMIHRDALRDAEQSLAVLARAFPDGGPTLARIPGLVSADPAERIAAVGA
                     LRAGDSGRFTGWSHHPAEVDTGTVARVLTHTLAQTVRHGKELLTSDSPSGPLRLDVWQG
                     AAGLGTELLHHLTDGTAQALAADLARNTAEHPLLNAYPQGLAFGRTGIAVFLAAAGRRL
                     DDDDLRGAARRAAPPDPGLLARVEYSDYAQGLAGIGAGHLMLAELTGDGAHLAVAAECA
                     RRIADGECLTSADDTADPTNGIVIGLGHAHGRAGLGAFLLAYHTVTGDRRAEAAAHVQY
                     AVLCERLPQVLAAAARPSARPMCASWCQGLSGIGTSLLRAAALGDDRCLRLAQDAAETS
                     LLMAPRMGIVTQCCGMAGVGELLVDLGAATGQNTWFGEAERVLGLMLDRCGGEPDTPAE
                     FPDNSLRGGSGGWATGSAGILTLLRRVRDHGGAGPWTFGQWTAA"
     gene            12568..13194
                     /locus_tag="F7P10_RS14795"
                     /old_locus_tag="F7P10_14795"
     CDS             12568..13194
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7P10_RS14795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7P10_14795"
                     /product="hypothetical protein"
                     /protein_id="WP_151009874.1"
                     /transl_table=11
                     /translation="MTTGTARPDTEERCAAGIDEQAVFGGRPQAVKTGSLAMLRELPGA
                     IGQTIGLLWTAGRGLTVTVLACQTAAAALTGLGLLAGTRVPAALLAGGPTPQRITAAPP
                     FLALVGGVLAARGALTAAVAEAQSRLTPRVLRHAHDRLYEATAAVELAAFDNPDWQEAL
                     SRARQRTLPAIELAVAELLAVAAAIAGLLAVGGIPATLHPCSWSC"
     gene            13382..13924
                     /locus_tag="F7P10_RS14800"
                     /old_locus_tag="F7P10_14800"
     CDS             13382..13924
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012235.4"
                     /locus_tag="F7P10_RS14800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14800"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_176611475.1"
                     /transl_table=11
                     /translation="MGRGRPESAAAPGTHPRPNHHGRTHARRDRRPDHPDRPRSAVERG
                     GGAAGRRRDRGHGDPCRAGVLRPARDHRQPVVRTRPIHRRLQPVPHRQPRARPSPHRRP
                     DAPRFRRDPFGRCHLLLPGTEKPTVEGVDLSLVQGEVIALVDENGSGKTTLARLLAGLY
                     RPTAGTIAWGGPSPRGG"
     gene            14030..14605
                     /locus_tag="F7P10_RS14805"
                     /old_locus_tag="F7P10_14805"
     CDS             14030..14605
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893413.1"
                     /locus_tag="F7P10_RS14805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14805"
                     /product="dihydrofolate reductase family protein"
                     /protein_id="WP_151009876.1"
                     /transl_table=11
                     /translation="MGFIKSSLFISLDGVIEAPETWHFPYFDDQMGAVVGELMGEAEAT
                     LLGRHTYEGFASYWPDADPADPMTEVMNSARKFVVSDTLTEATWRNSSLVNGDVAARLT
                     ELKADTRLGTTGSAALVRWMLEQGLVDELHLLVHPIVVGHGAKLFTDGRTVPLKLLSST
                     TFDATGVVHLVYTNGDTPKEGSATSAAS"
     misc_feature    complement(14054..14067)
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 18.47"
                     /tool="antismash"
     gene            14687..15421
                     /locus_tag="F7P10_RS14810"
                     /old_locus_tag="F7P10_14810"
     CDS             14687..15421
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (82-203). E-value: 2e-14. Score:
                     44.4. Matches aSDomain: nrpspksdomains_F7P10_RS14810_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020542977.1"
                     /locus_tag="F7P10_RS14810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14810"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_218040509.1"
                     /transl_table=11
                     /translation="MPGARYGIDSPYGFGFMGLVVLGFWVTGLVMAITADPAAALPALV
                     SGTLLAGCLALSLHATLRGKFLVWRDVLDELDLRGDERLLDLGCGRGAVLLAAARRLPR
                     GRAVGVDLWRGRDQSGNAPAATLRNARAEGVADRVHVQGGDLRRLPYAEASFDLVVSSL
                     TVHTILGADTRAQVIAEAYRVLRPGGRLLIADLARTPREYAAVLARLNAQDIRVRGLGW
                     RAWWGSPWVPTRLLTARKPATP"
     aSDomain        14933..15295
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F7P10_RS14810_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-14"
                     /label="F7P10_RS14810_oMT.1"
                     /locus_tag="F7P10_RS14810"
                     /protein_end="203"
                     /protein_start="82"
                     /score="44.4"
                     /tool="antismash"
                     /translation="RLLDLGCGRGAVLLAAARRLPRGRAVGVDLWRGRDQSGNAPAATL
                     RNARAEGVADRVHVQGGDLRRLPYAEASFDLVVSSLTVHTILGADTRAQVIAEAYRVLR
                     PGGRLLIADLARTPREY"
     gene            complement(15872..16912)
                     /locus_tag="F7P10_RS14815"
                     /old_locus_tag="F7P10_14815"
     CDS             complement(15872..16912)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070967 - coenzyme F420 binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009080327.1"
                     /locus_tag="F7P10_RS14815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14815"
                     /product="LLM class F420-dependent oxidoreductase"
                     /protein_id="WP_151009877.1"
                     /transl_table=11
                     /translation="MRIGTTLGYSGGFTQAAAELRDLEAAGVEIAFVAEAYSFDAVSQL
                     GYLAAVTERMRLASAILSIYTRTPALLAMTAAGLDHVSGGRFVLGLGASGPQVIEGFHG
                     VPYHAPIARTREIVEICRRVWRREAVVHRGRHYELPLPADRGTGLGKPLKLINHPVRPR
                     VPIMLAAIGPKNVELAAEVAESWLPVFVHPGRLHEVWGPSLAAGRARRDPELGPLDVVV
                     TMPLAIGDDVDHLLDLARPQLALYIGGMGARGKNFYNDLARRYGYEREAELIQELYLAG
                     RKKEAEAAVPEDLLRATSLIGPEKYVAERIAELAECGVTTVSVKPLAGPLDERVAAIER
                     LRDLMP"
     misc_feature    complement(16986..17001)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 17.13"
                     /tool="antismash"
     gene            17082..17876
                     /locus_tag="F7P10_RS14820"
                     /old_locus_tag="F7P10_14820"
     CDS             17082..17876
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015605179.1"
                     /locus_tag="F7P10_RS14820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14820"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151009878.1"
                     /transl_table=11
                     /translation="MLEIEGLVVRYGARSPVLHEVGLDVAEAGVVALLGANGAGKTSLM
                     RAVSGTLPLHGGSVAAGSIRFRGRDVTRGDPAAMVAAGLVQVPEGRHVFGALTVDENLD
                     AGAITVRSRGERARARDEMFGMFPRLAERRRQRAGTLSGGEQQMLAIARALMSRPKLLL
                     LDEPSLGLAPMLVKQIGEKVREISREGVPVLLVEQNAAMALEIADRAHVLELGRIVLSG
                     PADELSRSDEVGRLYLGDGAAGDPVGSPAGDPALPRLARWSA"
     gene            17873..18676
                     /locus_tag="F7P10_RS14825"
                     /old_locus_tag="F7P10_14825"
     CDS             17873..18676
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851135.1"
                     /locus_tag="F7P10_RS14825"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14825"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_151009879.1"
                     /transl_table=11
                     /translation="MSAPRLEMDAVTVAFSGLRALDEVSFTVEPGTVHAVIGPNGAGKS
                     SLLNALCGIYPLTGGRILLDEHEVTRLRPDRVAALGVGRTFQNIVASGRESVLDNLMVG
                     RHRLTRSGLVATALRLDRREQRRHEARVREIAEFVGLTPLLDATAGRLPYGDLKRLEFA
                     RALCLEPRLLILDEPVAGLNAAESRELGRLVLAARESLGLTVVFVEHDMGVVMSIADRI
                     TVLDFGRVVAGGTPAEVRRDPTVVNAYLGVPGDSGTGPAEERTPQ"
     gene            18673..19563
                     /locus_tag="F7P10_RS14830"
                     /old_locus_tag="F7P10_14830"
     CDS             18673..19563
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0015658 - branched-chain amino acid
                     transmembrane transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012851134.1"
                     /locus_tag="F7P10_RS14830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14830"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_151009880.1"
                     /transl_table=11
                     /translation="MTHLLELIANGVSLGLLYSLITLGFVIIFKATRVVNFAHASFLLL
                     GVYVVAAAQPRLGFAAAAVLGLAVTGLLALVAERLLIARIDQRDHHAMAIVTIGLNVVL
                     TAELTRRLGERMLPLGAPWDGHVVHLGPLSLPLTVVITVVAVPLLIGGLTALLTLTGWG
                     LAMRASIADAEGAALVGIRLRRVSALAWGTAGLLAATAGIGLASFPNPGVSVSLGAVAI
                     AAFPAAIIGGFDSLGGAIVGGLIVGVVQVLVSGYQDALSFLGLGVGDVVAYLVMIVVLL
                     WRPSGLFGSKEISRV"
     gene            19556..20734
                     /locus_tag="F7P10_RS14835"
                     /old_locus_tag="F7P10_14835"
     CDS             19556..20734
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131714.1"
                     /locus_tag="F7P10_RS14835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14835"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_254716607.1"
                     /transl_table=11
                     /translation="MSDDTLATARPAAEARAGVPPARSLPQRLRGAALPAAVLVALLAL
                     PFYVEVFWLRIGLFAMAAAVGALGLTILFGAAGQLSLGHAFFVAVGTYGYAFLSGEEQG
                     HVRGLGLPPLAAAVSATLLAGLCGLLFSPIAGRLRGIYLGIASLGLVFLGHHLLLNARP
                     VTGGYDGRAVEPFSLGGFTFSDASDLILLRVPFGAVESLWYLFLAVTAAATLVARNVLR
                     GRPGRAFRLVRDSEVGAATMGVRVDRTKASAFVLSSMFAGVAGVLTALAFQRAVPDYFD
                     LHLSIDFLAMIIIGGLGSTSGAIAGATFVIALPIVLARYADALPLIVGPGQNGLDASIA
                     AQFVYGALVVAIMLTRPGGLSAMVTAVRDRRARAAPPTPAPTPARDSVRRTP"
     gene            20731..21969
                     /locus_tag="F7P10_RS14840"
                     /old_locus_tag="F7P10_14840"
     CDS             20731..21969
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024850.4"
                     /locus_tag="F7P10_RS14840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_14840"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_151009881.1"
                     /transl_table=11
                     /translation="MIRFRPGPRTAVALALAVSVTGCSGKTVDPSATAPGVTDSTIKLG
                     VLADLSGPFATSGKTSNAAGQFAVEEINEAGGVCGRKLELVIRDHTYDVQKAVTAYDEV
                     EPQVLSFLNVFGSAVTTALRDKVAADDVLAGLTAFAPTLLGDPHLIVVGATYDVQAINS
                     IDFLKREGMLKKGDTLGHIYMQGEMGENSLKGSEYAAEQLGLKLVSQQIKPTDTDLTSQ
                     VNAMKAAGVKAILLDSTAQQTAAVAGSAQTAGLDVPIMGNVASFATSLLSTAAAPALTE
                     HYYRVSGVGLIGQDSPEVRKLADKYKAEYGPEQPESGGAVVLSYVTTHLFAEVIGNTCD
                     DLTREGVLAARAKVTDFTMPGLGPALNLSDPAQPSSRASQIHRPDKATYAGMKLVEDFR
                     TSDLAKRYRVQSG"
ORIGIN
        1 tcgggttcgg ccagcgctcg acgaacgtcg agaacgtgtc gtgcagcgcc ttgcgcgacc
       61 ggccgatcgt tccctccgcc gacctccggt cgtcgcccat ccgttccatg ccgcggcggt
      121 gcgcggcgtc gaactccttc agcgccgtcg ccgggtcggt gccgtccggg gcgtcgtcga
      181 acagcgccgc caggtactcc cggtgctccc ggctcacctc ggcgccggtc gccgcggcgg
      241 tgtcgagcgc cttctgggcg tcgtccacct cgtcgacgat cgcgtcccag gacccggcga
      301 gccgcttcac ctccgccttc tgcccgccga cgctctcggt cagccgggtg acctgctgct
      361 tgaggtcctc cgcctgctgc tgcagccggt cgatctccgg gttgcccgcg cggacctcgc
      421 cgatgatctg ctcccagcgg tcccgctcgg tggtgaccga ctcgacgtcc acctggtccc
      481 aggacagttc cgtcacggtc tggtaggcgt tgcgcctttc ctcgaacgag ttgaggttcc
      541 gctccgcctt cgccgcctgc gcgacggcgt cgtcgtggcg ctcctccgcg cggacgatcc
      601 gggcgtcgag gtcggcgagc agccgggtgt tggtgaaccc cagcaggttg gcccggccgt
      661 ggccgccgtg cgcgccccgg ccgcgctgcg acgtctggcc ggtgatcgtg agcgctttcg
      721 agtgctgcat cagcagcgcg ggcgtctcga cgcagacgta gtcgaagccg cgggagagtt
      781 cgctcttgag ccaggcggtg aacggcgacg accggtagtc gagccgaccg gggagcgtct
      841 tgtcgtccag cccgacctcg tcgcgcatgc cggtgcggac gccctcgaac cggatccgcc
      901 ggccgagctt caccgtgttg atcgcctcgc ggaacgcgtt cagccggccg atgtcgatca
      961 gcatccgggt ggcgaacccg ccgagcgcca ggttgaacgc ctcccgccac ggctcgaact
     1021 ccgtgcgcac ctcgatcagc tcgccgacga acggcagggc gtccggggtg agcccggcgg
     1081 cgtcggccag catgtcgcgg gcggcgtgca ggtcggtggg gatgttgccc cggcgggcct
     1141 tgaccgcgcc gcgctcggcc cgcaggtcgt ccagttcgcg ttcggcggcc ctcttctccg
     1201 ttgtcgcctc cgcgaactcg ttctgcgcgg tcctcctggc gtcggcgtcg gccagcgccc
     1261 ggtgcgccgt gtcgacgagc gcggcgaagt cctgcccgga cgacacggtg gcgccgaggg
     1321 tgccgagcac ccggtcgagc cgctgccggg cgcgttcgac gtcggccagc cgctgctccg
     1381 cgccgcggat ctcccggagc gcggtctcca accggtcgcc gccggacgcg cgcagggtgt
     1441 ccagcaccgc gtcccgctgg gactccgccg ccttgatcag cgtgaccgtc tccgccgcct
     1501 tcttctcggc ctggcggcgg cggacggtca ggtcctgctc ggcggcgcgc agcaggtcga
     1561 ggcggcgttc gtgccgccac agcgccgcgg gggacgccgg gtcggtgaac gatccgacgc
     1621 cgtcgatcac ccgcagccgc gtcaccgcgc cgtcgatcgc ctcccggtgc tcgcggatcg
     1681 gggtcagcgc ccgcacctgc cggtgggcgg tgatcatccg ctcccgggtg ccggacagct
     1741 cgtcgaactg ctgcaccacc tcgtccgccg tggccagggt ggacggctcc tccaggacca
     1801 tcgtcttgta cagtgcgtcg acggtggtga tctgctggcc cgcctggatc ctgccgagca
     1861 gcccgaccgc cttgtgcccg tccccggcgg cgccgatgcc cagcgtggtg tgcagccggg
     1921 cggtgaagtc ccgctcggtg ccgaagcagg tcaggcccgt cgcctcgacc gccggacggg
     1981 cgagccgccc ggccgcgggg ccgtccagct cacgcagatc gtagtcgtcg tcccgggtgg
     2041 cgcggaccac gacgacgtcg tcgagggtcc gcgcggccga cggcacgtac caggcgcgga
     2101 gcgcggtgaa caccgcgccg ctccggtcgg cccaggtcat cgcgatcgcc gtccaggtgt
     2161 cgcggccgtc gccgcgcagc acccgcagcc gcgtctcgcc gttcgtccgc gactcgtcga
     2221 gcttcccgcg cgcgtaggag aggatgttgc gctggtcctt gccgcggggg cggccggaca
     2281 ccccgccgtt ggacgccccg ttgaacggcg tggtgtgcgg catcagcaac gcgatgtagg
     2341 agtccatcag cgtcgacttg cccgacccgg aaccgccgct gaacagggtc gcaccggggg
     2401 cgaaccggat gcggtggtac ccgtcgtagc cgccccagtt gaccagttgc aggtcccgcg
     2461 cgacccactg ctgcccccgc gacgcggcgg ggatcaagcc gaacagcgtg tcgagcatgg
     2521 tcatggggcg gcctcgttcc gttcccgtag ccactggttc agctcggtga gcctctcggt
     2581 gctcagcacg acctcgacca gcggcgtgat gcggtaccgg cccgcggact cctccgcgag
     2641 cagcccttcc ttgaccagcc gctccaccgc cttgcggatc tcgtgctggc cgcgggcgag
     2701 gttgtggtcg tccgggtcga agtaggtcag cacggtctgt tccagctcct cgatgtcgac
     2761 ccgcgcggac gtctcgccgg tgccgcgctc ccgctggaag acggtccgca ggtggaccag
     2821 caccagggtc tcggcccggt tgtaggggtc gtccttcagc aggatcggga cgtcgagctc
     2881 cgccgagcgc acctgctgct tgtaggcgat gccccgctcg tggtcgacca cgagccggac
     2941 gaacaggtcg tgcagccgcg actcgatgat ctggtggttc tccagcagcg tgcgccactg
     3001 cgccgggctc ttctcggcca gcaggaacct gcgttgcagc agccgcacca gcagccgccg
     3061 gacgtccacg tcgagcgtgc ccgcgtcgcc ggcgaacagt tcggccgggt cgtcctccat
     3121 cgccaccggg tcgatgaacc cggcggcctc gacggccgac ccgccggcgc ccggcgagcc
     3181 cgcgccgtcc gtgccgtccg gttcgtcccg gacgtccggt tcactcatcg tcgcttcccg
     3241 gtgtctcggc cgcggcgcgg gggcgcgccg ggttcgcggc caggacaccg ccgaacgcga
     3301 gccgccgccg gctccggtcc ggccggacgg tctcgaccac cgcgacctcg gccgtgtcgg
     3361 ccatgccgag gtcgtgcgcg atctccagca ggccgaggag gtcgaccgga cgccggatcc
     3421 gctcgtcggc cgcacggaac gcggccgcca cgtcgacgcc gtccgtcccg tccgcgccgt
     3481 cggcgaaggc cgccaggtgc gcgtgcagat cggcgtactg cgggccgccc cacgcccggg
     3541 tgtccgcggt cggcacgtcc tccgtctcgt cccattcccg cagcggcgtg ggcggctgcg
     3601 gcggccgcgg gtcgctcatg gtctgccgca gctgcccgac gtcggccacc ggcaggcggc
     3661 gcagcgggtc gacggccgtg ccgcggcgcg acccgggcac ccacgcgtgc agtccggaca
     3721 tcacgtcccg cagcagctcg tccacctggc ggtcccgcat cgggtcgtgg tcgcgcacct
     3781 gggtggtgat gacgtgcgac gcctgccgct gcgcggtcag cacctccttg acgccctgct
     3841 cgatccggcg tgcgatctcg gcgagttccc gccgctgcgg ttccgccatc aggccggtga
     3901 acccgtgccg cagcacggtc cgcagcaggt tccacaggtc ttcgatctgc gccgggtcgc
     3961 cgatcaggcg gagcgccccg gcgaacgcgc gaccctccgg cgtcgcgtcc atgatctgcc
     4021 ggccgcgctc cagatactcg cgcagcacct ccccggtcgg ccgcacgtcc tgccgcagat
     4081 cggcgacgac gtctcgctgc atggccttga tcgactcggc gacgcgggcg aagtcggcgg
     4141 gcagctcccg cgccaggtgc agcacgttct cggccgcctc cagcaactgg tcgtcgtcga
     4201 cagtctcgac ggcgccgccc cgttcgagcc gctccagctc acggcgacgc tgatcgatct
     4261 ccgtctggag gcgcgccatc cgggccatca cgtccgggtc cgcgtcctgc gcgagccgct
     4321 cgaccgcctc cagcagcgtc cggacgcggg actccgacac ccgggtccgc gccccgccga
     4381 cccggcccgc cacctccagc gcgccgacgc cgtgggcgga cagccggtac acctcgacgt
     4441 cgtcggagac ctgccgcacc agccagcccg cctgcaccca ctgcctgcac aggtcacggg
     4501 cgttccccgc gggcaggggc tgatcgtcct cggagccgta gcccgcggcc cgcagctggt
     4561 cgagggcgtc ggcgatctcc gcgtgggcgt ccgccaccac caccgtcggc cgctccggcg
     4621 tgaacatcat cgccagcacc gtcaccacga acggcgcgta ggtccggtgg agcagatcga
     4681 gcatcgggtt ctggaacgcc cgaagcgcac cctgatacgc gccctccacg cctcgtgttc
     4741 ccatcgccga acaagggtag agcctggggc tgacaccgtg catccagccg ggttcccgaa
     4801 ctcgcgaggc ggatcatcca ggtcgcggag gacgcgcggg cgccccgttt ctggcgggca
     4861 accgtctgcg tcctgctctg cggggggtcg gtcaaaccgt cggtactcgg cggatacgta
     4921 gttctgtgga tggtgcggag tgaatcacct gaccgatcgt tgcgtagcac cgatgagcag
     4981 gaggcggcgt ggagatcaac gggcagggca ccacgctcga cgggacgctc cgctcctatg
     5041 tgccggaggt ggcggccgag gtgaccgtca ggattcgccg ggaggtgccg gccttggggg
     5101 cggcgcggta tctggattcg ttcgtggaga gcctcatcgg gcacttcctc gacctgctgg
     5161 acgagtccgg gccgccgtcc gacgagatcc tcgggcgggc ccgggaggcc ggtgttcggg
     5221 aagccgcgga gggccgtggc ccggacgtcc tgcccgccgc cgcccggctg ggtgccggga
     5281 tagcgatcgc caggttgagc gagcacgccg agcggttggg cctgcgcgtc gagatcagcg
     5341 cggtcgggaa gatcgcgcag atggtgttcg cctacaccga tcgcatcgcg gaggccgtca
     5401 tcgcgggcca cggcggctcc ggagcccacg ccgtcggcga agacgagaag cgtcggcggg
     5461 aactcctcga tctcctgctg accccgtgtc caggggcggc ggagatcaag gcggcggcgc
     5521 ggagcgccgg gtggccgatg ccgcgcaccg tcgcggtgat cgccctgggg gcgggcggtc
     5581 cccggccggt gcttccgccc gacgcgcttt tcggcctgca tttggacgag ccctgtctgc
     5641 tcctgccgga ccccgacggg cccgcgcggc gccgccaggt ggcggccggt ttgcgcggtc
     5701 ggacggcggc gatcgggccc accgtgggcg tagcggacgc ggcgaggtcg ctgcggtggg
     5761 cgtaccgcac gctgtcgctg gtcagaagcg gacgaatcac ggcggaggga agccggcccg
     5821 tccggtccgc ggaccatctg ccccggctca tgacgtcctg gggcgccgat ctggtggagc
     5881 tcgtggcggc cgaccggctc gccccgctgg acgccgtccg gccgtcggta cggcgggaac
     5941 tcgaggtgac cctgctggcg ctcctggagt gccatttccg ggcgatcgtg accgcggcgc
     6001 ggctgcatgt gcacccgcag accgtccgtt accggctccg caggctcgag gccctcttcg
     6061 gggaggagct ctacgagccg cggaaccagc tcgacatgca cttgctgctg tacgccagga
     6121 cgagagaccg agtgggcgcc gcaagagcgg actgacctgc gttttccctc cctggcggcg
     6181 gtcatcgaga tcggctaccg tgacggcctc atggaccttc cgcgcgccac caccagttac
     6241 gttggccggc gatgcgagac cgccgaggtc cgggcggcgt tggccgccgg acggctcgtg
     6301 acgctgacgg gcccgggtgg tgtgggcaag acccggctcg ccgccgcgac ggccgcacag
     6361 gtggccggag ggttcgccga cggtgccgtc ttcgtcgatc tcaccgagct tcgcgacggc
     6421 acgctgctac cggatctcgt cgccacccgg ctgggcctgc acaaccggtc gggtcagccc
     6481 gcgcgccggc tcgtcctgag tcatctgcgt gaacgcgcgc tgctgctcct gctggacaac
     6541 tgcgagcacg tggtggacga ggcggccgag ttcgccgccg cggttctggc cggatgcggc
     6601 ggtgtggccg ttctcgggac cggcaggcag tcgctcggcg tggcgggaga acgggttctg
     6661 cgggttccct cgctggcggt gcccgcggag gacgtcgcgg cctcgcccgc ggagctggcc
     6721 cgctacgacg cggtgcgcct gctcgtggat cgtgcctcga gcatcgttcc cgggttcgag
     6781 ctcacggccg ggaacggcgc ggccgtcgtg cggatctgcc ggcatctgga cgggctgccg
     6841 ctggcgatcg agctcgccgc ggccaggatg cgttccctgt cgccgcagca ggtcgccgac
     6901 cggctcaccc ggcggctgcc gctgcgcacg tccagcccgc gcacggcgcc ggaacggcaa
     6961 cggacgctgc gcgccaccat cgagtggagc ttctccctgt gctcgccggc cgagcaggcg
     7021 ctctggtcgc gggcgtcggt cttcgccggc acgttcgacc tgaccgcggc cgaacgggtg
     7081 tgcgcgggac ccggcctcgc ggccgaggag gtcctggacg ccgtggacgg cctgctcgac
     7141 aagtccgttc tgatccggga agaccacgga gacatcgtcc gctaccggat gctggagacc
     7201 ctccgcgagc acggccggga actcttggac caggcaggcc aacggagcgc ggtccgcctg
     7261 cggcaccgcg actggatcga ccggctgacc gcggcggccg acgcggactg ggtgagccgg
     7321 gagcagctgt cctggatcgt ccggctgagg ctggagcagg cgaacctgcg cgccgccctg
     7381 gaatggtcgc tgaccgagcc gggagaggcc ggggccgtac tgcggatcgc gtcccggctg
     7441 gacgagtact ggacgttctt cggtcacagc caggagtgcc gccagtggct cgaccgggcg
     7501 ctcgccatcg ccccgtccga tcaccccgat cggccgcgcg cactggccat ctgcgcgctc
     7561 cacggcgtct ggcatctgga cctggacgcg gcggagcgcc ggctcgccga ggcggaccgg
     7621 ttcgcgggcc cgcgggacga cctgctgcgg gcgctgctgg gttacgtgcg tgcgctcgcc
     7681 gcgcagatca ggaccgacac gtgtgccgcc gacctcgccg ccgaggcggc cgccgtgttc
     7741 cgcgcgcacg gggacgtgcg ccgggaactg catccgctgt ggatcttcgg ggtgtccacc
     7801 ggctaccgga agggcgacgt ggcggagggc cggcgggcgc tgcgccggat gctggaactc
     7861 tgcgaggcgc acggcgagac ccggtaccgc gccatggccc agttcggact ggcctatctg
     7921 gaggtcgagc ggggcgatgt cgagccggcc gaggaactcg cccgcgagtc cctgcggaac
     7981 ctcatgaaga tcggcgcggg ttccgggacc gcctacctgc tcgacaatct cgcctggatc
     8041 gcggaccgga agggcgagca cgtcaaggcc gccaccctct tcggcgcggc ggccacgctc
     8101 tggcgggcga tcgggtcggc gccggagatc gccgtgtccg gcccgcaccg cgcgcaccgg
     8161 gcgagcacgc tggccgcgct gggtgaggag cacttcggcc gcgcgttcgc cgcggggcgc
     8221 ggcatgaccg gtgcggaggc cgcgcggtac gcgctcggcg cggcggaacc cggcgagggc
     8281 gcccggccag gggcgctgac cggacgccag tgggagatcg ccgggctggt cgccgagggc
     8341 ctgaccaacc gggacatcgc ggccaagctg gtgatctccc agcgcacggc cgacacccac
     8401 gtccggaaca ttctggacaa gctcggtttc cgtaagcgtg ctcaggtcgc cgtctggttc
     8461 accgagcagc gctgacgtcc gacgggggcc cgggccgtca gcggagcgtg ggccgcaggt
     8521 cgcacttgtg gtcggcggcg aaatctgtgg ccttcccggg cccggacggt gtgcaggaga
     8581 tcatgcgggg cgccctgttc gagtaggcgg gccatactcg acggctcgcg ggcttcctgg
     8641 tcttggcaag tgaggaagcc tgagcggggt gtgcttgcca cgccgggcaa gcccacaaga
     8701 tcccggcatg ccggttgcgc ggctggagtc cccgaacacc gctggacctg gggtgtagcg
     8761 cctgctcggc gatccgtgca ccgactgaga aattgtggtc aggatgtcca ggcgggcggt
     8821 gagagtgcag gcgtcgggcg gcaggcgccg cagtgccggg gcctggcgag ttcgggatgg
     8881 tcctgggcgt ggtcgggggc ctgctgcacg cggcgaagcg gccagtccag tgcctcggcg
     8941 ggcacgtcac gggtgagagg gacggcggcc ggccggtccg gggggacggt gtagcgggta
     9001 ccaccctgca gcagccgctc cccgcgccgc cgctgcgatc gctgcggccg tgacgaccct
     9061 ggcagcgctg gccgcgcccg ccgacgccgc gaagcgaccc cgctcggtct cttcggccgc
     9121 gttcgtgggg ccgaccatgt cgtgcccgct gagaggcgcg cagggcggga cgatggcggg
     9181 cccgcgccgg gcggcacgcg ggcggcgagc cctccgctgg cacccgggcg gtcggcaaga
     9241 ccaggaacgc gcggcctgac gccggggcgg gacgcggtcc ggccggcggt gcaggctgat
     9301 caggaccttg gtggctcgcg ccccaccgac gtttggccgg gctgcttcgg gtagccggcc
     9361 gtcccacgcg gacttcccga tcgtgttcgc ggcagcgggt gacgcggcga atttgagaga
     9421 aaagtgatga acgccccagg tgccgacctt tccttatatt ggaggttcgg tgcggggtgt
     9481 gacggtgaga ggtcggtatc ttcgctgcta ctcgacccgc tctccgaggg agatggaacc
     9541 ttgttggtcg acgtgcaatt gtcgatgggc gctgcgagcg catgcaaaac aggaacgaca
     9601 aaagaatcgt ttgccggtac agccgaacat ggcgccggcg cttgggtgag aggagttgtc
     9661 gccatgaacg ccctgctcgt gggcccgcgc gacgcgggac cgtccaccgc agacctggac
     9721 atcgggttct tcgacagcga cgaggaggtc gccgcacacg gaccgcaggc gtgtgcgccc
     9781 acctgcaaca ccggcatgac gttcgtctgc gatggcgatt cggcccacac gtgcacctat
     9841 gggcaaacct tcgtctgcga cagctagcgt cgagtcggcg gagttcctga gccggaaagg
     9901 tggttgtttc tgcggccacc tttccggcgc caccgggtga gaggttaatg gattggtttc
     9961 ttcactgcgg ggcgagttgc tggccgatgg tctttctgaa atggtcggcg agttcggatg
    10021 gcggacccgc gccgggcggg tttgggtgca ttgtgatccg ccgtcggtgt cgcttccgga
    10081 acagggctgg aagattcatg tttccgctcg cccggccacg ttgccggaga cgttgcgggt
    10141 cgtggttccg cttctggtgc gccgggggtg cgcgttcaag gtggtcaacg ggcgggaggc
    10201 gctggccgag ttgaacgccc cggacgaccg cgtgtcgtcg gtgggcaagg cgatcacggc
    10261 ctatccgtcg ccggacctgt tccgggagct ggccgtcgag ttggcggagg cgctgcgcgg
    10321 gttcgccgcg ccggtggtgc gcagcgatcg ccgggtgcac cccgaggcgc cggtctacta
    10381 ccggtacggc ccgttcgcgg cccggtatcg ggtgagcctg aacggacagc ccgagctggt
    10441 ggtaaccggc ccggacgggg aagagtaccc gggagcggcc ggccggttct tcgactgccc
    10501 gccctgggaa cgcgacccgc tcagcgccga ccaaggaccg ccgccggatg ccgacgaagt
    10561 aacgccggtg ggcaagggcg cgccggtggg cgacggcgat cccggcgtgg tgctgggcgg
    10621 gcgctggcgg ttgcgggagg gtgtccggaa cagttcgcgc ggacggatct tccggggccg
    10681 ggacgtggtc accgggcggg aggtcgtcgt caaggaggcg cgagcctaca tcggtggtga
    10741 gacggccgac agcgactgcc gcgcgaacct gcgcagcgag cggcgggtgc tggcggcact
    10801 ggacggtgtc accggggttc cccaggtgct ggatcatttc cggcacggcg aggacgagtt
    10861 cctcgtgctg tcctccatgg ggcgacgcaa ccttgcggac gacgtcgcca cgtccggtat
    10921 ctaccccgac cggccgggcg agcgggacct gtcggtgctg gcgcgggaac tgctggtgct
    10981 cctggacgcc gtccacgagc gcggggtggt cgtgcgcgac ctgagtccca agaacgtggt
    11041 cttggacgag gcgggcggat gccatctgat cgacttcgag ctcgcccggc tcgacgggcg
    11101 gcaacgtccg ggatacagcc gcggctactg ctcgccggag cagttgcgcg gcgagccggg
    11161 cacggtcgcc gacgaccact tcgccgtcgg catgacactg ttctacgctg ccaccggcat
    11221 cgacccggtc atgatccacc gggacgcgct gcgtgacgcc gagcagtcac tggcggtgct
    11281 ggcgcgcgcg tttcccgacg gcgggccgac tctggcgcgg attccgggcc tggtcagcgc
    11341 cgaccccgcc gaacgcatcg ccgccgtcgg cgcgctccgg gccggagaca gcggccggtt
    11401 caccggctgg agccaccatc cggccgaagt agacaccgga acggtggcgc gggtgctgac
    11461 gcacacgctg gcccagaccg tccggcacgg caaggagctg ctcacctccg actcgccgtc
    11521 gggaccattg cggctcgacg tctggcaggg ggccgcgggt ctggggaccg agctgctgca
    11581 tcatctcacc gacggcaccg cacaggcgct ggccgccgac ctggcccgga acacggccga
    11641 gcaccccctg ctcaacgcct acccgcaggg actggccttc ggccggacgg gcatcgcggt
    11701 gttcctggcc gccgccggac ggcggctgga cgatgacgac ctgcgcggcg cggcgcgccg
    11761 cgccgcgccg cccgaccccg gtctcctggc gcgggtggag tactccgact acgcgcaggg
    11821 actggccggg atcggcgcgg gtcatctgat gctggccgag ctgacgggcg acggggccca
    11881 tctggccgtc gcggccgagt gcgcacgccg gatcgccgac ggcgagtgcc tcacctcggc
    11941 ggacgacacc gccgacccca ccaacgggat cgtcatcggc ctcggccacg cccacggacg
    12001 cgccgggctg ggcgcgttcc tgctcgccta ccacaccgtc accggcgacc ggcgggccga
    12061 ggccgccgca cacgtgcagt acgccgtgct gtgcgagcgg ttgccgcagg tgctggccgc
    12121 cgccgcgcgc ccctccgccc ggccaatgtg cgcgtcctgg tgtcaggggc tttcgggaat
    12181 cgggacatcc ctgctgcgcg ccgcagcact gggtgacgac cggtgcctgc ggctggccca
    12241 ggacgcggcc gagacgtccc tgctgatggc gccgcgcatg ggcatcgtca cgcagtgctg
    12301 cggcatggcg ggcgtcggtg aactgctggt ggacctcggc gcggccaccg gacagaacac
    12361 ctggttcggc gaggccgaac gggtgctggg actgatgctg gaccgttgcg gcggagaacc
    12421 cgacactcct gcggagttcc ccgacaactc cctgcgcggc ggcagcgggg gatgggccac
    12481 cgggagcgcc gggatactga cgctgctgcg ccgcgtgcgc gaccacggcg gcgccgggcc
    12541 gtggacgttc ggccagtgga cggcggcgtg accaccggca cggcacggcc cgacaccgaa
    12601 gaacggtgcg cggcggggat agacgagcag gccgtgttcg gcgggcggcc gcaggctgtg
    12661 aagaccggca gcctggcgat gctgcgcgaa ctgcccggcg cgatcggtca gaccatcggg
    12721 ctgctgtgga cggccggccg tgggctcacg gtcacggtgc tggcctgcca gaccgccgct
    12781 gccgcgctga ccggcctggg gctgctggcc ggcacccgcg tgccggccgc gctcctggcc
    12841 ggcggcccga ccccgcagcg gatcaccgcc gcgccaccgt ttctggcgtt ggtcggcggc
    12901 gtgctggcgg cgcgcggcgc gctgaccgcc gccgtcgcag aggcccagtc ccggctgacg
    12961 ccccgagtcc tccgacacgc ccacgaccgg ctgtacgagg cgaccgccgc cgtcgaactg
    13021 gccgccttcg acaaccccga ctggcaggaa gcactgtcgc gggcccgtca gcgcacactg
    13081 cccgccatcg aacttgccgt cgcggaactg ctcgccgtcg ccgccgccat cgccgggctg
    13141 ctcgcggtcg gcgggatccc cgccacgctg cacccctgct cctggtcctg ctgacggcct
    13201 ccgtcatccc gcacacctgg gccgcgatgc gcgccgcccg caccgcctac accggggaaa
    13261 tccccctcgc cgccctctac caccgccagc aactcatcgc agatctcatc accggccgcc
    13321 cggcggccgc cgagatccgt gcctacggcg ccgaacagtt cctgctcgcc gagtaccggc
    13381 ggtgggccga ggccgtccag aatcagcggc agcgcctgga actcacccgc gcccgaacca
    13441 ccatggccgg acgcacgctc ggcgggatcg gcgtcctgat caccctgatc gccctcggag
    13501 cgctgttgaa cgcgggggtg gtgccgctgg ccgccgccgc gaccgcggtc atggcgatcc
    13561 gtgccgggca ggcgtccttc gtccagctcg cgaccaccgc caaccggttg tacgaacgcg
    13621 gcctatacat cggcgacttc aaccggttcc tcaccgacag ccacgcgcgc gcccatcacc
    13681 ccaccggcga cccgatgccc cgcgatttcg ccgcgatccg tttggacgat gtcaccttct
    13741 gctacccggt accgagaagc ccaccgtcga aggcgtcgac ctgtccctcg ttcagggtga
    13801 ggtcatcgcc ctggtcgatg agaacggctc aggcaagacc accctggccc gcctgctggc
    13861 cggcctgtac cggcccacgg ccgggacgat cgcctggggc ggcccctccc cgcgtggcgg
    13921 gtgagagaaa atctcgggca cgtgtcgatc cgccgagacg ccgttcgacc tttggacgac
    13981 acacccgtcc ggggcggccg ccccggacgc cctcagaagg agcatcgcga tgggtttcat
    14041 caagtccagc ctcttcatct ccctcgacgg cgtgatcgag gcgccggaga cctggcactt
    14101 cccctacttc gacgaccaga tgggcgccgt cgtcggcgag ctgatgggcg aggccgaggc
    14161 gaccctcctc ggtcggcaca cctacgaagg gttcgcctcc tactggccgg acgccgaccc
    14221 cgccgatccg atgaccgagg tcatgaacag cgcgcgcaag ttcgtggtgt ccgacaccct
    14281 gaccgaagcg acatggcgga actcctcgct cgtcaacggc gatgtcgcgg cgaggctgac
    14341 cgagctcaag gcggacaccc ggctcggcac caccggcagc gccgcgttgg tccgctggat
    14401 gctggagcag ggcctggtgg acgaactgca cctgctcgtc cacccgatcg tcgtcggaca
    14461 cggcgcgaaa ctgttcaccg acggccggac cgtgcccctg aagctcctgt cctcgacgac
    14521 cttcgacgcc accggcgtcg tccacctcgt ttacacgaac ggcgacactc ccaaggaagg
    14581 atccgccact tccgcggcct cctgaacccg ggcactgtac tcggcggcgg tggaccagtg
    14641 cggcgtagtc ggcccccgag cgaccggttc gtggcagagt ggcgggatgc ccggcgcgcg
    14701 atacgggatc gactcgccct acgggttcgg cttcatgggc ttggtcgtgc tggggttctg
    14761 ggtgaccggg ctggtgatgg cgatcaccgc cgatccggcc gccgcgctgc ccgcgctggt
    14821 ctccggcacc ctgctggcgg gatgcctggc cctgagcctg cacgccacgc tgcgcggcaa
    14881 gttcctggtc tggcgggacg tgctggacga actggacctg cgaggcgacg aacggctgct
    14941 cgacctcggc tgcgggcgcg gcgccgtcct gctggccgcc gcccggcgcc tcccgcgggg
    15001 ccgggcggtc ggcgtggacc tgtggcgcgg acgggaccag tccggcaatg ccccggcggc
    15061 gaccctgcgc aacgcccgcg ccgaaggcgt cgccgaccgc gtccacgtgc aaggtggtga
    15121 cctgcgcaga ctcccgtacg cggaggcgag cttcgacctg gtcgtgtcca gcctgacggt
    15181 gcacaccatt ctcggcgcgg acacccgcgc ccaagtgatc gccgaggcgt accgggtgct
    15241 gcggccgggc ggccgcctgc tgatcgccga cctggcgcga accccccgcg agtacgccgc
    15301 ggtgctggcc cggctgaacg cccaggacat ccgcgtgcgc ggcctcggct ggcgcgcgtg
    15361 gtggggcagt ccgtgggttc cgacccgcct gctcaccgcc cgcaaaccag ccaccccctg
    15421 aacacgcccc ggtgacctca ggtcaggtgt ccgtgctccg gggaggctca gcgtgagtag
    15481 aagcttcggt tacgtccgga tcctcggaag ccagggcagc gacggcgcgc acggacgggc
    15541 gcccacaccc atcgcaggcg ccccactcct tcgcctccgc tgtggttgat cgtcggatgg
    15601 gcgcggtgtt cgacccacga cgccggtcgt caagcacttc ctggagccgc cggaagaagg
    15661 tccggaggag gagtcgccgc acttcgtcgg cgcggcaagg gcacccgacc ggtaacgccc
    15721 ggcggatcac gggatatgaa ggcgtccacg accggcacga gaacaccatc caccgaggcg
    15781 gcatccgtcc gcccccgggt cggagtgcgt tgcgcgtccg cccgggggcg ttcgcggtac
    15841 cgggccaccc ggcgcgtccg cccggacact gtcagggcat caggtcccgc aggcgctcga
    15901 tggcggcgac gcgttcgtcg aggggaccgg cgagcggctt cacgctgacc gtggtgacgc
    15961 cgcattcggc gagttcggcg atccgctcgg ccacgtactt ctcggggccg atgagcgacg
    16021 tcgcgcgcaa caggtcctcg ggaacggcgg cctccgcctc cttcttgcgg cccgccaggt
    16081 agagctcctg gatcagctcg gcctcccgct cgtagccgta ccgccgggcg aggtcgttgt
    16141 agaagttctt gccccgggcg cccatgccgc cgatgtagag cgccagctgc gggcgcgcca
    16201 ggtcgagcag gtggtcgacg tcgtcgccga tggccagggg catggtgacc acgacgtcca
    16261 gcgggcccag ctcggggtcc cggcgggccc gcccggctgc gagcgagggt ccccagacct
    16321 cgtgcagccg gccggggtgg acgaagaccg gcagccagct ctcagcgacc tcggcggcca
    16381 gttccacgtt cttggggccg atggcggcca gcatgatcgg gacgcggggc cggaccgggt
    16441 ggttgatgag cttcagcggc ttgcccagcc cggtcccgcg atcggccggc agcggaagct
    16501 cgtagtgccg gccgcggtgc acgaccgcct cgcgcctcca cacgcggcgg cagatctcca
    16561 cgatctcgcg ggtccgggcg atcggggcgt ggtaagggac gccgtgaaag ccctcgatca
    16621 cctgcgggcc ggacgcgccg agaccgagga cgaacctgcc gcccgacacg tggtcgagcc
    16681 cggccgcggt catggcgagc agcgccggcg tccgggtgta gatcgacagg atcgcggagg
    16741 cgagccgcat gcgctcggtg accgccgcca ggtacccgag ctggctgacg gcgtcgaagg
    16801 agtaggcctc cgcgacgaag gcgatctcga ccccggcggc ctcaaggtcg cgcagttcag
    16861 cggccgcctg cgtgaaaccg ccgctgtagc cgagggtcgt gccgatccgc atagcgaacc
    16921 tccaggatca gacagggccg ggcgggccgt cgcggcccgc tccgaccggc cgaagtgttg
    16981 acgcctgtga cgccgctcac ctacattacg ctacttaacg aacgatcgat agctagaact
    17041 taacgaacgt tcgacagggc acagggcagc gaggaggccg gatgctcgaa atcgaagggc
    17101 tcgtcgtccg ctacggcgca cgaagcccgg tactgcacga ggtgggcctc gacgtcgccg
    17161 aggcgggcgt ggtggcgctg ctgggcgcca acggcgcggg caagacctct ctcatgcgcg
    17221 ccgtctcggg cacgttgccg ctgcacggag gatcggtcgc cgccgggtcg atccggttcc
    17281 gcggacggga cgtcacccgg ggcgacccgg cggccatggt ggccgccgga ctggtgcagg
    17341 tccccgaggg gcggcacgtg ttcggcgcgc tcaccgtcga cgagaacctc gacgcgggcg
    17401 ccatcaccgt ccgttcccgc ggcgagcggg cgcgcgcccg cgacgagatg ttcggcatgt
    17461 tcccccggct ggccgagcgg cgccgccagc gcgccggcac gctgtccggc ggcgagcagc
    17521 agatgctggc catcgcccgc gcgctgatgt cccggccgaa actgctgctg ctcgacgagc
    17581 cctccctcgg cctggcgccg atgctggtga agcagatcgg cgagaaggtg cgcgagatca
    17641 gccgcgaggg cgtccccgtg ctgctggtgg agcagaacgc ggcgatggcg ctggagatcg
    17701 ccgaccgggc gcacgtcctg gagctgggcc ggatcgtgct gagcgggccg gccgacgagc
    17761 tgtcccgcag cgacgaggtc ggccggctct acctgggcga cggcgcggcc ggcgatccgg
    17821 tcggcagccc ggccggcgac ccggccctgc cgcggctggc ccggtggtcg gcatgagcgc
    17881 gccccgcctg gagatggacg cggtcaccgt cgcgttcagc ggcctgcggg cgctggacga
    17941 ggtgtcgttc accgtcgagc cggggaccgt ccacgcggtc atcggcccca acggggccgg
    18001 caagtcgtcg ctgctcaacg cgctgtgcgg catctatccc ctgaccggcg ggcgcatcct
    18061 gctggacgag cacgaggtga cgcggctgcg accggaccgg gtcgcggcac tgggagtcgg
    18121 caggaccttc cagaacatcg tcgcctcggg gcgggagtcg gtgctggaca acctgatggt
    18181 cgggcggcac cggctgaccc gctccggcct ggtcgcgacc gcgttgcggc tcgaccgccg
    18241 cgagcagcgc cggcacgagg cgcgggtgcg ggagatcgcc gagttcgtcg gcctcacacc
    18301 gctgctggac gcaaccgcgg gacggctgcc ctacggcgac ctcaagcgcc tggagttcgc
    18361 ccgggcgctg tgcctggagc cgcgcctcct catcctcgac gaacccgtgg ccggcctgaa
    18421 cgccgcggag agccgggagc tgggacggct cgtcctggcg gcgcgcgagt ccctcggcct
    18481 gaccgtggtc ttcgtggagc acgacatggg cgtggtcatg tcgatcgccg accgcatcac
    18541 ggtgctggac ttcggccggg tcgtcgcggg cggcacgccc gcggaggtgc gccgggaccc
    18601 gaccgtggtc aacgcctatc tcggcgtgcc gggcgattcc ggtaccggcc ccgcggagga
    18661 gaggacgccg caatgaccca tctgctggaa ctgatagcca acggcgtgtc cctgggcctg
    18721 ctgtactcgc tcatcacgct cggcttcgtc atcatcttca aggccacccg ggtggtgaac
    18781 ttcgcgcacg cgtcgttcct gctgctcggg gtgtacgtcg tggccgccgc ccagccgcgg
    18841 ctcgggttcg ccgcggcggc cgtgctcggg ctcgcggtca ccggcctgct cgcactggtc
    18901 gccgagcggc tgctgatcgc ccgcatcgac cagcgggacc accacgcgat ggcgatcgtc
    18961 acgatcggcc tcaacgtcgt gctgaccgcc gagctgaccc ggcgcctcgg ggagcggatg
    19021 ctgccgctgg gcgcgccgtg ggacggccac gtggtgcacc tcggccccct cagcctgccg
    19081 ctcacggtcg tcatcaccgt ggtggccgtg ccgctgctga tcggcggtct caccgcgctg
    19141 ctcacgctga ccggctgggg actggcgatg cgggcgtcca tcgccgacgc cgagggggcg
    19201 gccctggtcg gcatccggct gcgccgggtc tccgccctcg cctgggggac ggccgggctg
    19261 ctggccgcga cggccggcat cggcctggcc tcgttcccca accccggtgt cagcgtgagc
    19321 ctcggggcgg tcgcgatcgc cgcgttcccc gcggccatca tcggcgggtt cgactcgctc
    19381 ggcggggcca tcgtcggcgg gctcatcgtc ggtgtcgtcc aggtgctggt gtcgggctac
    19441 caggacgcgc tgtcgttcct cgggctcggc gtcggtgatg tcgtcgccta cctcgtgatg
    19501 atcgtcgtgc tgctgtggcg gccgtccgga ctgttcggct ctaaggagat cagccgtgtc
    19561 tgacgacacc ctcgccaccg cccgtccggc cgccgaggcg cgggcgggcg tcccaccggc
    19621 ccggtcgctg ccgcagcggc tgcgcggtgc cgccctcccg gcggccgtgc tggtcgcgct
    19681 gctggccctg cccttctatg tcgaggtgtt ctggctgcgc atcggcctgt tcgcgatggc
    19741 cgccgccgtc ggggcgctcg gcctgaccat cctgttcggc gccgccgggc agctgtccct
    19801 cgggcacgcg ttcttcgtcg ccgtcgggac gtacgggtac gcgttcctct ccggtgagga
    19861 gcagggccac gtcagggggc tggggctgcc gccgctggcg gccgccgtgt cggcgaccct
    19921 gctggccggg ctctgcggcc tgctgttcag cccgatcgcc ggccggttgc gcggcatcta
    19981 tctcggcatc gcctcgctgg ggctggtctt cctcggccac cacctgctgc tcaacgcacg
    20041 gccggtgacc ggcggctacg acgggcgcgc ggtcgaaccg ttctcgctcg gcgggttcac
    20101 cttctccgac gcctcggacc tgatcctgct ccgcgtcccc ttcggagccg tggagagcct
    20161 gtggtacctg ttcctcgcgg tcaccgccgc ggccacgctg gtggcccgca acgtgctgcg
    20221 gggccggccc ggccgggcgt tccgactcgt gcgcgacagc gaggtgggcg ccgccaccat
    20281 gggcgtgcgc gtcgaccgga ccaaggcgtc cgcgttcgtc ctgtcctcga tgttcgccgg
    20341 cgtcgccggc gtgctgaccg cgctggcctt ccagcgcgcg gtacccgact acttcgacct
    20401 ccacctgtcc atcgacttcc tcgccatgat cattatcggc ggcctggggt cgacgtccgg
    20461 cgcgatcgcc ggcgcgacct tcgtgatcgc gttgccgatc gtgctggccc ggtacgcgga
    20521 cgcgctgccc ctgatcgtcg gaccgggcca aaacgggctg gacgcgtcca tcgccgcgca
    20581 gttcgtgtac ggcgcgctcg tcgtggcgat catgctgacc cggcccggcg gcctgagcgc
    20641 gatggtgacc gccgtccgcg accggcgcgc gcgggccgca cccccgaccc ccgcacccac
    20701 ccccgcccgc gactccgtca ggaggacccc atgatccggt tccgtccggg cccccgcacc
    20761 gcggtcgccc tcgcactcgc cgtgtccgtc accggatgct cgggtaagac cgtcgatccc
    20821 tcggcgaccg ctcccggcgt caccgattcc accatcaagc tgggcgtcct ggccgatctc
    20881 agcggcccgt tcgcgacgtc cggcaagacc agcaacgccg cgggccagtt cgccgtcgag
    20941 gagatcaacg aggccggcgg cgtgtgcggc cgcaagctgg aactggtcat ccgggaccac
    21001 acctacgacg tccagaaggc cgtcacggcc tacgacgagg tcgagccgca ggtgctgagc
    21061 ttcctcaacg tcttcggctc ggcggtcacc acggcgctgc gggacaaggt ggccgcggac
    21121 gacgtgctgg ccggcctcac ggccttcgcc cccaccctgc tcggcgaccc gcacctcatc
    21181 gtggtcggcg ccacctacga cgtccaggcg atcaacagca tcgactttct gaagcgggag
    21241 ggcatgctga agaaggggga caccctgggc cacatctaca tgcagggcga gatgggcgag
    21301 aacagcctga agggcagtga gtacgcggcc gagcagctgg ggctgaagct ggtgagccag
    21361 cagatcaaac cgaccgacac cgacctcacc agccaggtca acgcgatgaa ggcggccggc
    21421 gtgaaggcga tcctgctgga ctccacggcc cagcagaccg cggcggtggc cggttccgcg
    21481 cagaccgccg ggctggacgt gccgatcatg ggcaacgtcg cctcgttcgc caccagcctg
    21541 ctgtcgacgg cggccgcacc cgcgctgacg gagcactact accgggtgtc gggcgtcggg
    21601 ctcatcggcc aggactcgcc ggaggtgcgc aagctcgccg acaagtacaa ggccgaatac
    21661 ggcccggagc agcccgagtc gggcggcgcc gtcgtactgt cctacgtgac cacccacctt
    21721 ttcgctgagg tcatcggcaa cacctgcgac gatctgacgc gcgagggcgt gctcgcggct
    21781 cgcgccaagg tgaccgactt caccatgccc ggcctcgggc cggcgctgaa cctgtccgac
    21841 ccggcgcagc cgtcgtcgcg ggcgagccag atccaccgcc ccgacaaggc gacctacgcc
    21901 ggcatgaagc tggtcgagga cttccggacc tccgacctcg ccaagcgtta ccgggtgcag
    21961 tcggggtgac cgcgccctcg ccggcggcac cgccgccggc cggtgcggat catgaaggca
    22021 agctgacaca gagaagtggg agatgatggt acgcggcact ggggatgcgg cggccgatcg
    22081 cctgccggcg gcggtggccc ggggcgacgg gctcaccgcg atcatgcggg cggcgcgcac
    22141 cgttttcgcc gatcgcggct accacggcgc gtcgatccgg gacatcgcca aggaggcggg
    22201 gctgagcctg tcggccctgt actactacta ctccggcaag caggacctgc tccacgcgct
    22261 gctggaggac acgctggccg actaccgcag cagttgcacc gaggtgctgg ccgaggccgg
    22321 ggacgacccg gccgcgcgcc tgcgcggctt cgtgcgagcc accgtggagt accgggtgcg
    22381 gcgccaggtc gacagcctgc tcgccctcca ggagacgcgc aatctggaac cggaccggct
    22441 ggaaagcttc gccgaacggc gcgacgcgct gccggggctg ctgcgcgaga tcatcgagga
    22501 cggtgtggcg ggcgggctgt tcgccacgcc gtaccccgat gaggcgcagc ggacgatcct
    22561 ggcgatgtgc a
//
