LOCUS       NZ_CP044407            26067 bp    DNA     circular CON 28-JUL-2024
DEFINITION  Actinomadura sp. WMMB 499 strain WMMB499 chromosome, complete
            genome.
ACCESSION   NZ_CP044407
VERSION     NZ_CP044407.1
KEYWORDS    RefSeq.
SOURCE      Actinomadura sp. WMMB 499
  ORGANISM  Actinomadura sp. WMMB 499
            Bacteria; Actinomycetota; Actinomycetes; Streptosporangiales;
            Thermomonosporaceae; Actinomadura.
REFERENCE   1  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Draft genome of Actinomadura sp. WMMB499
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 9187113)
  AUTHORS   Braun,D., Bugni,T.S., Chevrette,M.G. and Currie,C.R.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-SEP-2019) Pharmacy, University of Wisconsin-Madison,
            777 Highland Ave., Madison, WI 53705, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Canu v. Oct-2016
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 300.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008824145.1-RS_2024_07_28
            Annotation Date                   :: 07/28/2024 05:00:58
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,523
            CDSs (total)                      :: 8,413
            Genes (coding)                    :: 8,251
            CDSs (with protein)               :: 8,251
            Genes (RNA)                       :: 110
            rRNAs                             :: 5, 5, 5 (5S, 16S, 23S)
            complete rRNAs                    :: 5, 5, 5 (5S, 16S, 23S)
            tRNAs                             :: 92
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 162
            CDSs (without protein)            :: 162
            Pseudo Genes (ambiguous residues) :: 0 of 162
            Pseudo Genes (frameshifted)       :: 64 of 162
            Pseudo Genes (incomplete)         :: 108 of 162
            Pseudo Genes (internal stop)      :: 10 of 162
            Pseudo Genes (multiple problems)  :: 19 of 162
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 04:12:41
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1389399
            Orig. end                         :: 1415466
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP044407.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Genome not circularized.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26067
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="6"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26067
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26067
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16067](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16067
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(479..1306)
                     /locus_tag="F7P10_RS05975"
                     /old_locus_tag="F7P10_05975"
     CDS             complement(479..1306)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017604152.1"
                     /locus_tag="F7P10_RS05975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_05975"
                     /product="ABC transporter permease"
                     /protein_id="WP_151008440.1"
                     /transl_table=11
                     /translation="MTVQGKTAEETLGEQIRWAFADCWTIVLRGLTHYVRQPSNIAWQL
                     GFPIVSVLLFGYVFGSAMSVPGGGDYREFLMPGMFGMTMAMGFMNTAYAVVYENTRGVT
                     DRFRSMPMAPSAVVTGRGVGDLIAASLDLLVLFLTALVIGWRTDGGPLATLGAFGLFLL
                     LRFGLIWIGILLGMLIPNEEAAGSLFAVAFPFAMISSAFVAPSLMPDWLGTIAMWNPVS
                     STVTASRELFGNPAAVGDTWIEQNALLMAIVWPLVITAVFLPLAVRRYQNLSR"
     gene            complement(1303..2304)
                     /locus_tag="F7P10_RS05980"
                     /old_locus_tag="F7P10_05980"
     CDS             complement(1303..2304)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634525.1"
                     /locus_tag="F7P10_RS05980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_05980"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_151008441.1"
                     /transl_table=11
                     /translation="MPDNAILCEGVRKHYGNKHALDGFDLTVPAGTVYGLLGPNGAGKT
                     TAVRILATLIRPDGGRAEVAGIDVAARPRRVRRRIGLAGQHAALDEVLTGRQNLRMFGR
                     LFHLGRAAAARRADELLARFDLVEAADKGVKHYSGGMRRRLDLAAAMILAPDVLFLDEP
                     TTGLDPRSRNEVWHSVRSLVEQGTTVLLTTQYLDEADQLAGRIAVLDRGRVIADDTPDG
                     LKRLVGADRIEVVVRDPADLPATAEVIARVTAAEPLVEAAVARVHAPVTDGVAALTEIA
                     RTLQDDGVGVADIGLRRPTLDEVFLRLTGHRADDAGTAAPGAAEPTKEGART"
     misc_feature    2342..2360
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.3"
                     /tool="antismash"
     misc_feature    complement(2346..2364)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.24"
                     /tool="antismash"
     gene            2466..3233
                     /locus_tag="F7P10_RS05985"
                     /old_locus_tag="F7P10_05985"
     CDS             2466..3233
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014906.4"
                     /locus_tag="F7P10_RS05985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_05985"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151008442.1"
                     /transl_table=11
                     /translation="MTTEHGDHRDPQRSLKLLWGDRARPPRGRPPTLTLEAIVAAAVET
                     ADELARTEGLEALTMRSIATRLGVGTMSLYRYVPGKGELLDLMLDHVIGEYEPAEEEHG
                     PSGWRDVLAGDAHRQWRMCMEHPWYPFVDQSRPILGPNSLHGLDRVLGLLRPIGVPDRT
                     LMMMIGTQSDYVDGVARSCINERRAVERTGLSGEDFWAAQAPTLEKAVLSGRFPAMAAA
                     DENTFDWSYEQIFEFGLNRLHDGFASFLGERSG"
     gene            3286..4452
                     /locus_tag="F7P10_RS05990"
                     /old_locus_tag="F7P10_05990"
     CDS             3286..4452
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009082104.1"
                     /locus_tag="F7P10_RS05990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_05990"
                     /product="glycosyltransferase"
                     /protein_id="WP_151008443.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 2e-21, bitscore:
                     75.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLILDVLAPAALAGWIYLAAGHGGFWRTGGGPVDTAEPRAWPDVV
                     AVVPARDEASVLPETLPALLAQDYPGRFEVVLVDDGSTDGTAGTARRLADGMPDGAAAG
                     LRVLPAGERPDGWAGKVWAMREGVAAAGEPEFVLFTDADIAYAPGTVERLVRAAAGADL
                     DLVSRMATLGTRTPWERALVPAFVYFFALLYPFRRVGRPGARTAAAAGGCMLVRRAVLV
                     RAGGLAAIRGALIDDVALGRLIKRAGGRCRLDLDRDVVSRRRYPRPADLWDMVARSAYD
                     QLRYSPALLAGTVLGLVLLFAVPPAAAVAGTVAGAPAAAVPGLAAWTIMAGTFAPMLRH
                     HRLSPLRAPTLPLVALVYAAMTLDSARRYHTGRGGVWKGRAAVGRAAR"
     gene            complement(4453..5055)
                     /locus_tag="F7P10_RS05995"
                     /old_locus_tag="F7P10_05995"
     CDS             complement(4453..5055)
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017544273.1"
                     /locus_tag="F7P10_RS05995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_05995"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_151008444.1"
                     /transl_table=11
                     /translation="MPRTVDKQARRRDVADALFRIAAREGLDGVSMRTVATEAGFSLGA
                     VQRYFQTKDEMLSFAFARAAEAARARLAAIRAEPDGRTFPEELRRAMLGYLPADESRLA
                     EARIWAAFHAEAAVRPAFADALNELDAEARANLRAAIAAAQETGGLPAGRPAEELAELI
                     LVLLDGLWWSAVRRPPGAPLTVQRDVIDTAIAMLTAR"
     misc_feature    5240..5254
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.08"
                     /tool="antismash"
     misc_feature    complement(5353..5371)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.63"
                     /tool="antismash"
     misc_feature    5360..5376
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 24.15"
                     /tool="antismash"
     gene            5379..5738
                     /locus_tag="F7P10_RS06000"
                     /old_locus_tag="F7P10_06000"
     CDS             5379..5738
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7P10_RS06000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7P10_06000"
                     /product="hypothetical protein"
                     /protein_id="WP_151008445.1"
                     /transl_table=11
                     /translation="MVAALAAIAGLGLTVAGARRRDGTGGGSGGGSGGGSGEEGAAALH
                     GSTVGGSATVVGRVGGSVRLTGTRTPRDRAPRDLPQPEPGGDAAAGGASISRSAVDGDA
                     FVAGTVDGDVETRPE"
     gene            5893..7971
                     /locus_tag="F7P10_RS06005"
                     /old_locus_tag="F7P10_06005"
     CDS             5893..7971
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017539.4"
                     /locus_tag="F7P10_RS06005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06005"
                     /product="NACHT domain-containing NTPase"
                     /protein_id="WP_151008446.1"
                     /transl_table=11
                     /translation="MDGRGEDPLPARPERLRLGWASTGRPVSPAGAARGDLRGDVSELA
                     ARFRELPVRHLVVLGAPGSGKTVLAIRLLLDLVNPDDPAEPVPVLLPLSSWSPEASSLH
                     DWMAARIAEDHPFLDAATAGDLLKSTKVTPVLDGLDELAPRLRGTAVEAVDAWAADGRP
                     VVLTCRGNEYERTVRGSGSPLSRAAVVEIGDVRPADAAAYLRAAALDGGTRWDALLDRL
                     ADAPDGPLGEALSTPLMVELLRTAYRAPATDPAELLDAERFPSRESVEGHLIDRFVPAL
                     YAPALRPAYRADRAERWLAFLARRMRRHDTVSISWWEIWTLPSALLLTLPFALTGALVF
                     GSIFGTTRGLVAAGLFAVAAAASLAPGAAAAPVRERDLTDPVALLRRLRGGSAGWALLV
                     AVVSGVLIGTWFGLGLHASTAKTVTYALLLAGMFAIGALGGTAWGSFALSRSWFASTGR
                     LPFRLVAFLRDAHERGALRQVGAVYQFRHALVRDRLGLGVQAQERAFHGGWRLPPRWIA
                     PARVGVQVAGVLLATLVLTAPLTAATLHHRSGDRPAERTEVVQSGAQGTEVPVQFLEWT
                     LPPGATRTTVFTVQHRDTRFPVIELTTVTFLTRGCGGASVEFTAVAGGRTVAHQRLDIR
                     PFGSRRDLGREDFAGRPETVTVSLERVDDADCTVVFRWQEPRILYDRLLDVREYLRS"
     gene            7976..>8350
                     /locus_tag="F7P10_RS06010"
                     /old_locus_tag="F7P10_06010"
                     /pseudo=""
     CDS             7976..>8350
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /GO_process="GO:0019748 - secondary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016533.4"
                     /locus_tag="F7P10_RS06010"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06010"
                     /product="aminoglycoside phosphotransferase family protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MAGWTIVDELARNAVNTWGGVGRRWLDGLPRLVKEVARDWRLDVG
                     ATFDLSFHWVAAVRREDGTAAVLKLGPPEPGHLGHEAAALEAFAGRGAVRLLGRDAERG
                     ALLLERAEPGTMLRDLVPDRD"
     gene            8533..8895
                     /locus_tag="F7P10_RS43165"
                     /old_locus_tag="F7P10_06015"
     CDS             8533..8895
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /GO_process="GO:0019748 - secondary metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016533.4"
                     /locus_tag="F7P10_RS43165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06015"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_254716731.1"
                     /transl_table=11
                     /translation="MCADSGERFVLHGDLHHDNVLRGGREPWLAIDPHGLVGDRGYEIG
                     PVLYNPDPDVRDERLLGLVPARVERLADGLGMPVERAVAWGFASCVLSEVWEAQGGEPG
                     GRALDVARLLLPMLPA"
     gene            complement(8900..9882)
                     /locus_tag="F7P10_RS45310"
                     /old_locus_tag="F7P10_06020"
                     /pseudo=""
     CDS             complement(8900..9882)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022427.4"
                     /locus_tag="F7P10_RS45310"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06020"
                     /product="DUF2804 domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPEREIAAPVDLCLPDGRLNPAAVGWTRRPLHTANLRGWGRAKRW
                     EYWGIVTPRHIVGLVASSLDYAGVHGVYVLDRETGEELNRDAVVPFALGARFPDRSGEG
                     TASVRGGGVAVGARAEPGGTRLRALAPAIGVDLDLTVPVPDGHESLGVVIRGPRTASST
                     R"
     misc_feature    complement(9941..9958)
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.93"
                     /tool="antismash"
     gene            10001..10687
                     /gene="hpnC"
                     /locus_tag="F7P10_RS06025"
                     /old_locus_tag="F7P10_06025"
     CDS             10001..10687
                     /EC_number="2.5.1.21"
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03464.1"
                     /locus_tag="F7P10_RS06025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06025"
                     /product="squalene synthase HpnC"
                     /protein_id="WP_218040393.1"
                     /sec_met_domain="phytoene_synt (E-value: 4.3e-37, bitscore:
                     126.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.1e-43,
                     bitscore: 148.5, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITDSPWNVEEHDRALARLAAGENFPVAARLLPKRIRADLTAVYG
                     FARLVDDIGDEAPAEQRGKLLELVDDDLDRVYGGATPELPQLRRLARAVHARSIPDEPF
                     RRLVQANRQDQTVHRYETWDELVAYCRLSADPVGRIVLHVFGASGRGLEESSDLVCTAL
                     QVIEHCQDVGEDFRRGRVYLPAEDLRRFGCTDGDLGRTRTPTRLRGVVALEAARARDLL
                     DRGRRR"
     gene            10969..11774
                     /locus_tag="F7P10_RS06030"
                     /old_locus_tag="F7P10_06030"
                     /pseudo=""
     CDS             10969..11774
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012705.4"
                     /locus_tag="F7P10_RS06030"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06030"
                     /product="squalene/phytoene synthase family protein"
                     /pseudo=""
                     /sec_met_domain="phytoene_synt (E-value: 4.6e-23, bitscore:
                     80.7, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.5e-27,
                     bitscore: 94.3, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVPKRRAMSAVYAFARGVDDIGDGPEPACVRLDLLDRSRGRIAA
                     VRDVLEHRADAAVLEGHPVLTALADAAARYPIPLEAFDELIDGCESDVRGADYETFDDL
                     LQYCRQVAGTVGRLSLAIFGTQGRLRRRRSRTPSASPCSSPTSCGTCARTGSRDASTCR
                     PRTSSASTARSNWTTRACSSTRRRG"
     gene            11771..13090
                     /gene="hpnE"
                     /locus_tag="F7P10_RS06035"
                     /old_locus_tag="F7P10_06035"
     CDS             11771..13090
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634146.1"
                     /locus_tag="F7P10_RS06035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06035"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_218040394.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 9.4e-07, bitscore:
                     27.3, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 5.9e-10, bitscore: 38.2,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVVIVGGGLAGISAAIALRESGVPVTLLEARPWLGGATHSFERG
                     ELSVDNGQHVFLRCCTAYQGLLQRLGADHLVDVQDRFDVTVLRPGAAAARLTRSRLPGP
                     LHLLPALARYPHLTRGERLRAMRAAAALRRLDPTDARLDQIAAGPWLAARGQRPWAREA
                     LWGLFITASLNAEVDDAALGLSAMVCRRGLFGRADAADIGVPVVPLEELHGGPALRRIA
                     EMGGTVRLKAKVEAVTTDPKVVVDGVPIAADAVIVAVPHEAAAKVLPAEALPDPLRWRE
                     LDSSPIVNVHVVYDRPVMGEPFAAAVGSPVQWIFDRTGVSGLRDGQYLAVSLSAADRWI
                     DRPTAELRDRFVPELARLLPAARGARVRELFVTRERRATFRQRPGTGAVRPAAATRAPG
                     LFLAGAWTDTGWPDTMEGAVRSGLTAARLVRRHLEGVRDR"
     gene            13108..14142
                     /locus_tag="F7P10_RS06040"
                     /old_locus_tag="F7P10_06040"
     CDS             13108..14142
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634145.1"
                     /locus_tag="F7P10_RS06040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06040"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_176611321.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 9.5e-59, bitscore:
                     197.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDVRGLVDGALRAAVGRLDPRTYRVAAYHLGWADAEGHPRAAPA
                     GKALRPALALLSARAAGAAQESALPGAVAVELTHAFSLLHDDIMDGDLTRRHRPAAWAV
                     FGEADAILAGDALLSLAVEVLLEAPGQGSARAARALSAATRRLIGGQARDLEFESRRTV
                     SLDECVAMASDKTAALLACSCSIGAVLDGAPEPLCTALAEFGADLGIAFQLVDDLLGVW
                     GDPEITGKPALSDLRSRKLSLPVVAALNAGTAQSERLAELYAAPGSDGADGDADGESGD
                     GAEDARLEEMARLVEAAGGRAWAEAEAGRRIERAAARITSAGLPTAIRAEFLHIADFVT
                     GRDH"
     gene            14142..16067
                     /gene="shc"
                     /locus_tag="F7P10_RS06045"
                     /old_locus_tag="F7P10_06045"
     CDS             14142..16067
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634144.1"
                     /locus_tag="F7P10_RS06045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06045"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_151008448.1"
                     /sec_met_domain="T2TS (E-value: 2.4e-150, bitscore: 500.6,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTTEPIHPAPEQAAPERAAAEAAGAMRTPAEALAAAREHLLALQ
                     SPEGWWKGELQTNVTMDAEDLLLREFLGVRTEDDTRETARWIRSQQAEDGTWATFHGGP
                     SDLSTTAEAYVALRLAGDAPDEPHMARASAFVRARGGVPETRVFTRFWLAMFGEWSWDD
                     LPVLPPEMMFLPRWFPLNVYDFACWARQTIVPLTIVGSLRPVRPLPFDLPELRAEHPAR
                     RSGRRRVPGWDEAFHTLDRALHVYERRPVRALRQAALRRAGEWIVARQEADGCWGGIQP
                     PWVYSLIALHLLGYRNDHPVMKRGLDGLERFTIRDAKGRRLEACQSPVWDTVLAMNALA
                     DAGVPGDDPAQRRAADWVLGEEVTGPGDWSVRRPNLPPGGWAFEFDNDVYPDTDDTAEA
                     ILALDRVGHPAAEPAIERAVRWMAGMASADGGFAAFDADNTRELCRRLPFCDFGEVIDP
                     PSADVTAHVVEALARRGMADSRTVKRAVVWLLRAQERDGSWFGRWGANHVYGTGAVVPA
                     LIAAGVRPGKPAIRRAVRWLERHQRPDGGWGEDLRSYDDPGWIGRGASTPSQTAWALLA
                     LLAAGERGPAVDRGVRWLIEHQRQDGTWDEDHFTGTGFPGDFYINYHLYRLVFPVSALG
                     RYVREA"
     gene            16069..17073
                     /gene="hpnH"
                     /locus_tag="F7P10_RS06050"
                     /old_locus_tag="F7P10_06050"
     CDS             16069..17073
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634142.1"
                     /locus_tag="F7P10_RS06050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06050"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_151008449.1"
                     /sec_met_domain="PF04055 (E-value: 4e-18, bitscore: 65.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 3.8e-08, bitscore: 32.0,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGMPLRQSLRVGGYVLKNKLARRAKFPLLVELEPLFACNLACAGC
                     GKIQHPADVLKQRMPVEQAVAAIRECGAPMVSIAGGEPLMHPKIGELVRELIRMKRYVF
                     LCTNAALIPRKIDQFEPSPYFAWAVHIDGLRERHDASVCKEGVFDEAVAAVRMCKKRGF
                     RVTTNTTVFNTDTPQTVIDVLNYLNDDLRVDQMMISPAYAYEKAPDQDHFLGVQETRSL
                     FQKAFANGNRKRWRFNHSPLFLDFLEGKVDFPCTAWAIPSYSLKGWQRPCYLMDDGYAE
                     TYRELIEETDWDSYGRGRDDRCANCMAHCGYEPTSVFATMGSLKESIRAMRAV"
     gene            complement(17343..19361)
                     /locus_tag="F7P10_RS06055"
                     /old_locus_tag="F7P10_06055"
     CDS             complement(17343..19361)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF025736.4"
                     /locus_tag="F7P10_RS06055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06055"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_151008450.1"
                     /transl_table=11
                     /translation="MLGTPAVTARDAVLTREGDAARAHAFGEVLLGLALFALYLLVAML
                     PEEPRARLARAHGETLYELERVLHLDVELALNEWLADQSVLRVLANYEYAITYVVSALA
                     LLVWLFLRHPGRYRTARTAFVLLNVIALACFALYPVMPPRLMPDLGFVDTVRLGGTWGS
                     WGSPLVEHADRFAALPSLHMAWTLWVGVELARVNAHRSVQAVNTVHIVVTGYVIMATAN
                     HYLVDAVAAVPLVAVSVYAAERLARPSAERVRAPDAFFLAVETERAPQHTGGVIMLDTS
                     RDPVERADVIRLVAGRMDRLPRLRQRPDGAGRWRRPVWRDHPALDWNWHVAEHHVAGMD
                     GLREVIARVQAEPFPRDRPLWRILLVRGAEPGRTAVVFLMHHVVADGVGVVAQAASLME
                     PPQDPAPAGPPRGRVRTALTAAAGTAIGLAQLAVDVAPPARLPAAGTPERRFGTLHLPL
                     DLVRDVSRRHGVRVTDVVLCAVAGGLHRVARPGGNERGTCRVAVPLMMRAPGGAMEGNH
                     TSAVMVDLPIGAMAEPERLADIARRCKVLRSGTRALAAWFVMRQVGRLMPVPLHARFAR
                     AAYSERFLQGIVSSLPGPGGPLRLAGAPLAAVYPVVPLAPGAPLAVAALGVSRELCFGV
                     SLDPGLVDDADTLTAAIGDVIAELHTTPKPETPAPQL"
     misc_feature    complement(19473..19487)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.76"
                     /tool="antismash"
     gene            19608..20243
                     /locus_tag="F7P10_RS06060"
                     /old_locus_tag="F7P10_06060"
     CDS             19608..20243
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019631347.1"
                     /locus_tag="F7P10_RS06060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06060"
                     /product="PadR family transcriptional regulator"
                     /protein_id="WP_254716433.1"
                     /transl_table=11
                     /translation="MPGSGPLFGGGPGFGPWGPPGGFGPGGPGPRPPWAHGRRGGPWGR
                     GAKARKGNVRAAILALLAEEPRNGYQVIQQIAERSEHAWRPSPGAVYPALQQLADEGLI
                     AADETGGRRAYRLTEAGRAYVEEHADELREPWAAMAWDFGEGVPELFKQAAQTGAAVMQ
                     IVHSGRPEQLDRARDVLSTARRDLYRILADAPAGSDDADPGPDAREGS"
     gene            20240..20719
                     /locus_tag="F7P10_RS06065"
                     /old_locus_tag="F7P10_06065"
     CDS             20240..20719
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019656.4"
                     /locus_tag="F7P10_RS06065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06065"
                     /product="DUF1707 domain-containing protein"
                     /protein_id="WP_151008452.1"
                     /transl_table=11
                     /translation="MTDELRIGDAERDAVVVALHDHFAAGRLDRAELDGRMDAALAAKT
                     RGDLAALVRDLPPPHGLPEAARARPAPVPGPGPAPWGRPGPMYGGPHHPRHRHRHHMHP
                     HHHGPPGPAFPLLLAVFLVLTFTVGAGTGLLAVLGIAMVAWLARAARLAASVRRS"
     gene            complement(20716..21642)
                     /locus_tag="F7P10_RS06070"
                     /old_locus_tag="F7P10_06070"
     CDS             complement(20716..21642)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1014: LysR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656756.1"
                     /locus_tag="F7P10_RS06070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06070"
                     /product="LysR family transcriptional regulator"
                     /protein_id="WP_254716434.1"
                     /transl_table=11
                     /translation="MIDLRRLHMLRLVHQYGTVTSAAEAMHLTPSAVSHHLRELGRELK
                     VPLLEPQGRRVRLTPAAHVLIGHADALLARWEETVADLESHRTGAAGPLRMCGFTTAVS
                     GLIAPAAGRLRRADPRLPIEIRECDTAEAMALLAAGDTDIAVIEPSADAPPPGDPRFDR
                     EPLLEEAMDLIVPAGHPLAARGIARLEDAAAEPWISVRPESCDHHHRLLAHCAAAGFTP
                     RVEHSTATWSVIWALVAAGLGVSLVPRLVGGPGEGAVRVPLAGPSVPRRRLLTCVRRGG
                     RGNPLVERGLRALRDAVPEPCTRLPAA"
     misc_feature    complement(21686..21699)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: medium, score:
                     16.73"
                     /tool="antismash"
     gene            21716..21895
                     /locus_tag="F7P10_RS06075"
                     /old_locus_tag="F7P10_06075"
     CDS             21716..21895
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F7P10_RS06075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F7P10_06075"
                     /product="hypothetical protein"
                     /protein_id="WP_151008453.1"
                     /transl_table=11
                     /translation="MTQCSTTEQRPVIVSRHLTSDGVVLWTRCSCGRLRMDLVPDGPGG
                     SRLTAGPCPHVPAG"
     gene            complement(21926..22828)
                     /locus_tag="F7P10_RS06080"
                     /old_locus_tag="F7P10_06080"
     CDS             complement(21926..22828)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006313 - DNA transposition [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013752.4"
                     /locus_tag="F7P10_RS06080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06080"
                     /product="transposase"
                     /protein_id="WP_368077456.1"
                     /transl_table=11
                     /translation="MCEDKPGRPSDRTLRPSGRPRPAIGRPAPQTRPRPDPQRRRAGLR
                     RHRPSPARVRFRAPVAADRARTDRAPVPPAARPVRVQPAPARRRPRPGGRSGVAGPPDP
                     VLARPAAADGRHPAALRRLPHHRAPLRAGRDRRLRHGQVPPRLLLGSQAHADHHPEGAV
                     CSFSVAHPKELDERKQAIHLLHARPPAPGPCPIVCDKGFAGAGVEKTAAGLGHLLIRPV
                     RQDEPEPPVKVFPAWLRQRIEAVIWTLKNQLGLERHAARTTEGLWTRLCQRICALNAVI
                     WHNWLIGAPVKRSLIAYDH"
     gene            complement(22887..23507)
                     /gene="eda"
                     /locus_tag="F7P10_RS06085"
                     /old_locus_tag="F7P10_06085"
     CDS             complement(22887..23507)
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /GO_function="GO:0008675 -
                     2-dehydro-3-deoxy-phosphogluconate aldolase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008700 - 4-hydroxy-2-oxoglutarate
                     aldolase activity [Evidence IEA]"
                     /GO_process="GO:0009255 - Entner-Doudoroff pathway through
                     6-phosphogluconate [Evidence IEA]"
                     /codon_start=1
                     /gene="eda"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012852102.1"
                     /locus_tag="F7P10_RS06085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06085"
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="WP_151008454.1"
                     /transl_table=11
                     /translation="MNAEDLFDLAPVIPVVVLDDADAAVPLARALVAGGLPAIEVTLRT
                     PVAIEAITRIAAEVPDAVVGAGTVVRPDDAERSAAAGARFLVSPGCTERLRTAMAATGL
                     PFLPGAATASEAVALLEAGVTAMKFFPAEPAGGIPYLKALNGPLPQVRFCPTGGVKPGN
                     AADYLALPNVGCVGGTWLTPADAVRSGDWERIRKLAAEAAALR"
     gene            complement(23504..24505)
                     /gene="glk"
                     /locus_tag="F7P10_RS06090"
                     /old_locus_tag="F7P10_06090"
     CDS             complement(23504..24505)
                     /EC_number="2.7.1.2"
                     /GO_function="GO:0004340 - glucokinase activity [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="glk"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018656759.1"
                     /locus_tag="F7P10_RS06090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F7P10_06090"
                     /product="glucokinase"
                     /protein_id="WP_151008455.1"
                     /transl_table=11
                     /translation="MTAPWLVGDIGGTNARFALVDGPDGAPRDVRALPTREHADLADAA
                     LAYLSRYAPGVRPSAACLAVAGPVTGGTFHLTNAGWPVGTPGDVRDRLGVPHLEIVNDF
                     AGLAMSLPRLAADDLVPVGDRYPAADGPVAVVGPGTGLGVGGLVPVPGGGWVPLPGEGG
                     QVDAPAGTDLEGEVVRLLRAERGAATAEYLLSGDGLARIHRYLAIIDGVPPEPVTPAAI
                     VERAQRPGSRDPRCARTLAMFCELLGSLAGNVALTIGATGGVYLGGGILPRIAGVLKDS
                     AFRARFEGKPPVEGYLRAIPTALIVHPGPALVGAAMRLAQTAPEPARPLESA"
     misc_feature    25418..25433
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 20.8"
                     /tool="antismash"
ORIGIN
        1 cgcgcgcggg cgaccggctc cccctgcacg ccaccggcat ggggaaggcg ctactcgcct
       61 tcgcccggcc ggagctcacc gcggagatcg tccgggaggg gctgacccgc tacacgccgc
      121 acaccctcac ctcgccggag ctgctgcgcc gcgcgctcgt ccggacacgg gagcaggggt
      181 tcgcggtcgc cgtgcaggag tactcgctgg gaaccgtctc cgtcgccgcg cccgtgctgt
      241 cacccgaccg gcggcacgcg gtcgcggcga tctccgtcgt cgtgcacagc tcccgcgcga
      301 acatcgcgcg gctcggaccg gccgtccgcg cggcggcgat gggcgcggcc cggcacgtct
      361 cccgcccggc ccgggacgcc gggtaggcga ggtcgttgag gcggcggagg acgtgggccg
      421 tctccgccgc ccgccacggg gcggacggcc gtggcgggcg gacggccgcc ccgtccgcct
      481 agcggctcag gttctggtag cggcggacgg ccaggggcag gaagaccgcc gtgatgacga
      541 gcggccaaac gatcgccatg agcagggcgt tctgctcgat ccaggtgtcg ccgaccgcgg
      601 ccgggttgcc gaacagctcg cgggacgcgg tcaccgtcga ggagaccggg ttccacatcg
      661 cgatcgtgcc cagccagtcc ggcatcaggg acggcgcgac gaacgcgctc gagatcatcg
      721 cgaacgggaa cgcgaccgcg aacaggctcc cggcggcctc ctcgttcggg atcagcatgc
      781 ccagcaggat gccgatccag atcagcccga agcgcagcag caggaacagc ccgaaggcgc
      841 cgagggtcgc gagcggcccg ccgtcggtcc gccagccgat caccagggcc gtcaggaaca
      901 gcacgagcag gtccaggctc gcggcgatca ggtcgccgac gccccggccg gtgaccacgg
      961 cggacggcgc catcggcatg gagcggaacc ggtcggtgac gccgcgcgtg ttctcgtaga
     1021 cgacggcgta cgcggtgttc atgaacccca tcgccatcgt catcccgaac atgccgggca
     1081 tcaggaactc gcggtagtcg cctccgccgg gcaccgacat cgcgctgccg aacacgtacc
     1141 cgaacagcag gaccgagacg atggggaagc cgagctgcca ggcgatgttg ctcggctgcc
     1201 ggacgtagtg cgtcaggccc cgcaggacga tcgtccagca gtcggcgaag gcccagcgga
     1261 tctgctcgcc gagggtctcc tcggccgtct tgccctgcac ggtcacgtcc gcgccccttc
     1321 cttcgtcggc tccgccgcgc cgggggcggc ggtgcccgcg tcgtcggccc ggtgccccgt
     1381 gagccgcagg aacacctcgt ccagcgtcgg tcggcgcagc ccgatgtccg ccacgccgac
     1441 gccgtcgtcc tgcagggtgc gggcgatctc ggtcagcgcg gccaccccgt cggtgaccgg
     1501 cgcgtgcacc cgcgctaccg ccgcctcgac cagcggttcg gcggccgtga cgcgggcgat
     1561 gacctccgcc gtcgcgggca ggtccgccgg gtcgcgcacc acgacctcga tccggtcggc
     1621 gccgaccagc cgcttcaggc cgtccggcgt gtcgtcggcg atgacccggc cccggtcgag
     1681 gacggcgatg cgcccggcga gctggtcggc ctcgtccagg tactgggtcg tgagcaggac
     1741 ggtcgtgccc tgctcgacca gcgaccggac ggagtgccag acctcgttgc ggctgcgcgg
     1801 gtcgagcccg gtcgtcggtt cgtcgaggaa caggacgtcc ggtgcgagga tcatcgcggc
     1861 ggcgaggtcg aggcggcggc gcatcccgcc gctgtaatgc ttgaccccct tgtcggcggc
     1921 ctcgaccagg tcgaaccgcg ccagcagctc gtcggcccgg cgcgccgccg ccgcgcgccc
     1981 caggtggaac agccggccga acatgcgcag gttctgccgt cccgtcagga cctcgtccag
     2041 cgcggcgtgc tgcccggcca gcccgatccg gcggcgcacc cgccgggggc gcgcggcgac
     2101 gtcgatcccg gccacctcgg cccggccgcc gtccggccgg atgagcgtgg ccaggatgcg
     2161 cacggcggtc gtcttgcccg ccccgttcgg ccccagcagg ccgtagacgg tgcccgccgg
     2221 caccgtgagg tcgaagccgt cgagcgcgtg tttgttcccg tagtgcttgc ggaccccctc
     2281 gcagaggatc gcgttgtccg gcatctcgtc tcccgcccct acttcgcgta tcaagtacgc
     2341 taattcgcgt acaggatact cgaagtgagt tcgagcgcaa ccgggtttcc gcgcgcggtc
     2401 gcggacgcgc gaggcggtag cgtctctcgc gccacggccg gcacacggga agagcaggac
     2461 ggacgatgac gaccgagcac ggcgaccacc gcgatcccca gcggagcctg aagctgctgt
     2521 ggggcgatcg cgcccgcccg ccgcgcggcc gcccgcccac gctcacgctc gaggcgatcg
     2581 tcgccgccgc cgtggagacc gccgacgagc tcgcgcggac cgaagggctc gaggcgctca
     2641 cgatgcggtc catcgcgacc cgcctcggcg tcggcacgat gtcgctgtac cggtacgtcc
     2701 cgggcaaggg cgaactgctg gacctcatgc tcgaccacgt catcggcgag tacgagcccg
     2761 cggaggagga gcacggcccc tccggctggc gcgacgtgct cgcgggcgac gcccaccgcc
     2821 agtggcggat gtgcatggag cacccctggt acccgttcgt ggaccagagc cgccccatcc
     2881 tcgggccgaa ctccctgcac ggcctggacc gcgtcctcgg cctgctccgg cccatcggcg
     2941 tcccggaccg gacgctgatg atgatgatcg gcacgcagag cgactacgtg gacggggtgg
     3001 cgcgcagttg catcaacgag cgccgcgccg tggagcggac cggcctcagc ggcgaggact
     3061 tctgggccgc gcaggcgccc accctggaga aggccgtgct cagcggccgg ttcccggcca
     3121 tggccgcggc cgacgagaac accttcgact ggtcctacga gcagatcttc gagttcggcc
     3181 tgaaccgcct gcacgacggc ttcgcatcct tcctcggcga gcgctccggc tgacccggcc
     3241 cgccgggtcc ttggcccggc gggaccggcg tgcgacgctg ccgctgtgct gatcctggac
     3301 gttctcgccc cggcggcgct cgccggctgg atctatctcg ccgcaggcca cggcgggttc
     3361 tggcggaccg gaggcgggcc ggtggacacc gcggaaccgc gcgcgtggcc ggacgtcgtg
     3421 gcggtcgtgc cggcccgcga cgaggcgtcc gtgctgccgg agacgctccc ggccctgctc
     3481 gcgcaggact acccgggacg gttcgaggtc gtgctcgtcg acgacggcag caccgacggg
     3541 acggcgggca cggcgcggcg gctcgcggac ggcatgccgg acggcgcggc cgccgggctg
     3601 cgcgtactgc ccgcgggcga gcgtccggac ggctgggccg gcaaggtctg ggcaatgcgg
     3661 gagggggtgg ccgcggcggg cgaacccgag ttcgtcctgt tcaccgacgc cgacatcgcc
     3721 tacgcgcccg gcaccgtcga acggctcgtg cgggcggccg ccggcgcgga cctcgacctg
     3781 gtgtcgcgga tggcgacgct cggcacccgg acgccgtggg agcgggcgct cgtccccgcg
     3841 ttcgtgtact tcttcgcgct gctgtacccg ttccgccgcg tcggccgtcc cggggcccgc
     3901 acggccgccg cggcgggcgg ctgcatgctg gtgcgccgcg ccgtgctggt gcgggcgggc
     3961 gggctcgccg cgatccgcgg cgcgctcatc gacgacgtcg cgctgggacg gctgatcaag
     4021 cgcgcgggcg gccggtgccg gctggacctg gaccgcgacg tcgtcagccg ccgccggtac
     4081 ccgcgcccgg ccgacctgtg ggacatggtc gcgcgcagcg cctacgacca gctccgctac
     4141 tcccccgccc tgctggcggg cacggtgctc ggcctggtgc tgctgttcgc ggtcccgccc
     4201 gccgccgcgg tggccgggac cgtcgcgggc gcccccgcgg cggccgtccc cggcctggcc
     4261 gcctggacga tcatggcggg cacgttcgcg ccgatgctgc gccaccaccg gctctcgccg
     4321 ctgcgcgccc cgaccctccc gctggtggcg ctggtgtacg cggcgatgac gctggactcg
     4381 gcccgcaggt accacaccgg acgcggcggc gtctggaagg gccgcgccgc cgtcggacgg
     4441 gccgcgcgct gatcagcggg cggtgagcat cgcgatcgcg gtgtcgatca cgtcgcgctg
     4501 gacggtcagc ggggcgccgg gcgggcggcg gacggcgctc caccacaggc cgtcgagcag
     4561 gacgaggatc agttcggcga gttcctcggc gggccggccg gccggcagcc cgcccgtctc
     4621 ctgggccgcg gcgatcgcgg cgcgcaggtt cgcgcgggcc tcggcgtcga gctcgttgag
     4681 ggcgtcggcg aacgcgggcc ggacggcggc ctcggcgtgg aacgccgccc agatccgggc
     4741 ttcggcgagc cggctctcgt cggccggcag gtagccgagc atcgcccggc gcagctcctc
     4801 ggggaacgtc cgcccgtccg gctcggcccg gatcgccgcc agccgcgccc gcgcggcctc
     4861 cgccgcccgc gcgaaggcga agctcagcat ctcgtccttg gtctggaagt agcgctgcac
     4921 cgcgccgagc gagaaccccg cctcggtcgc gaccgtccgc atgctgacgc cgtccagccc
     4981 ttctcgcgcg gcgatgcgga acagggcgtc cgcgacgtcg cggcggcggg cctgcttgtc
     5041 caccgtcctc ggcacctctc cattctgccg cacgcacgcg gcgttaattc cggcagtgcg
     5101 ttcacattgc cgttggcggc tttacggaga tcgaccggcc gggatctcgc ggaggccgtt
     5161 ttcggctcct cggtaccggg ttttcggccc ttgcggaagc cgcgctcatc ggtgccgggt
     5221 tgtaccttgg tcgtccttga tgatcctgaa gattggggtc tcggatgcgt cgagtggtcg
     5281 gttcgcggac cgttctcgtg gcgacgggcg tgatcgtgct gggagccgcc gggctctttt
     5341 tcgcactggg cctcgataat gcagacaaac tgggcagcgt ggtcgcggcc ctggcggcga
     5401 tcgcaggtct ggggctgacc gtggccggag cgcgccgccg ggacgggacg ggcggcggct
     5461 cgggcggcgg ctcgggcggc ggctcgggtg aggaaggcgc ggcggcgctg cacggctcga
     5521 ccgtcggcgg gtcggccacc gtggtggggc gggtcggcgg gagcgtccgg ctgaccggca
     5581 cgcgcacccc gcgcgaccgg gcgccgcggg acctgccgca gccggagccg ggcggcgacg
     5641 cggcggcggg cggcgcctcg atcagccggt cggcggtcga cggcgacgcc ttcgtggccg
     5701 ggaccgtcga cggcgacgtg gagacgcgtc ccgagtgagc aggcgcaggc cgcgggcgtc
     5761 catggagggt tcgaccgtcc tcggggacgc gttgctggtc ggttcggtcg gcggcgatgt
     5821 ccatgtgggc gtggcgcccg agcaccggac ggacgccgcg gtgcgggcgc tcgcggaggc
     5881 ggtgcggcac cagtggacgg ccgaggcgaa gatcctctac ccgcgcgccc cgagcggctc
     5941 cggctgggct gggcgagcac gggccgcccc gtctcgcccg ccggagcggc gcgcggcgac
     6001 ctgcgcggcg acgtctccga gctggccgcg cggttccgcg aactgccggt gcggcacctg
     6061 gtcgtcctcg gcgcccccgg ctcgggcaag accgtactgg cgatccggct gctcctcgac
     6121 ctggtgaacc cggacgaccc ggccgagccc gttcccgtgc tgctgccgct gtcgtcgtgg
     6181 tccccggagg cgtcgtcgct gcacgactgg atggccgcgc ggatcgccga ggaccatccc
     6241 ttcctcgacg ccgcgaccgc cggggacctg ctgaagtcca cgaaggtgac gcccgtcctg
     6301 gacggcctgg acgagctggc cccgcgcctg cggggcacgg cggtcgaggc cgtcgacgcc
     6361 tgggcggcgg acggccgtcc ggtcgtcctc acgtgccgcg ggaacgagta cgagcggacc
     6421 gtccggggaa gcgggagccc gctgagccgc gcggcggtcg tggagatcgg cgacgtgcgg
     6481 cccgccgacg ccgccgccta cctgcgggcc gccgccctcg acggcggcac ccgctgggac
     6541 gcgctcctgg accggctggc ggacgccccg gacgggccgc tcggggaggc gctgtccacc
     6601 ccgctgatgg tcgagctgct ccgcaccgcg taccgggcac cggcgacgga cccggcggag
     6661 ctgctggacg cggagcggtt cccgtcgcgg gagtcggtcg aggggcactt gatcgaccgg
     6721 ttcgtgcccg ccctctacgc gcccgcgctc cggcccgcgt accgggccga ccgggcggag
     6781 cggtggctcg ccttcctcgc ccggcggatg cggcggcacg acaccgtgag catctcctgg
     6841 tgggagatct ggacgctccc gtcggcgctg ctgctgacgc tgccgttcgc gctgaccggc
     6901 gccctggtct tcgggtcgat cttcggcacg acccgggggc tggtcgcggc gggcctgttc
     6961 gccgtggccg cggccgcgtc gctcgccccg ggggccgcgg cggcgcccgt ccgggagcgg
     7021 gacctgacgg acccggtggc gctgctgcgg cggctgcgcg gcggctcggc cgggtgggcg
     7081 ctgctcgtcg cggtggtgtc cggggtgctc atcgggacgt ggttcggcct cggcctgcac
     7141 gcgagcacgg ccaagacggt cacgtacgcg ctgctgctgg cgggaatgtt cgcgatcggc
     7201 gcgctcggcg gcaccgcgtg gggctcgttc gcgctgtccc ggtcgtggtt cgcctcgacc
     7261 gggcgcctgc ccttccggct ggtcgccttc ctgcgggacg cccacgagcg cggcgcgctc
     7321 cggcaggtgg gggccgtcta ccagttccgc cacgcgctcg tccgggaccg gctcggcctc
     7381 ggcgtgcagg cccaggagcg cgccttccac ggcgggtggc ggctgccgcc ccgctggatc
     7441 gccccggccc gggtcggcgt gcaggtggcg ggggtgctgc tggcgaccct ggtcctgacc
     7501 gccccgctca cggcggcgac cctgcaccac cggtcggggg accgtcccgc cgagcggacc
     7561 gaggtcgtcc agtcgggcgc gcagggcacg gaggtgcccg tccaattcct ggagtggacg
     7621 cttccccccg gggcgacccg cacgacggtg ttcaccgtgc agcaccggga cacccggttc
     7681 ccggtcatcg agctgaccac cgtcaccttc ctgacccgcg ggtgcggcgg agcctccgtc
     7741 gagttcacgg ccgtcgccgg agggcggacg gtggcgcacc agaggctcga catccgcccc
     7801 ttcgggtccc gccgcgacct gggccgcgag gacttcgcgg gccggcccga gaccgtcacg
     7861 gtctccctcg agcgcgtcga cgacgcggac tgcacggtcg tgttcaggtg gcaggaaccc
     7921 cgcatcctct acgaccgcct gctggacgtc cgcgagtacc tgcgctcgtg aggtgatggc
     7981 aggctggacg atcgtggacg aactcgcgcg gaacgccgtg aacacgtggg gcggcgtcgg
     8041 gcggcggtgg ctggacgggc tgccgcggct ggtgaaggag gtcgcgcgcg actggcggct
     8101 ggacgtcggc gcgacgttcg acctgagctt ccactgggtc gcggccgtcc ggcgggagga
     8161 cgggacggcg gcggtgctga agctcgggcc acccgaaccg gggcatctgg ggcacgaggc
     8221 cgccgcgctc gaggcgttcg ccggacgcgg cgcggtgcgg ctgctcggcc gcgacgcgga
     8281 gcgcggggcg ctgctgctgg agcgggcgga accgggcacc atgctgcgcg acctggtgcc
     8341 ggaccgcgac ggcgccgcga cggacgcgct ggtcgaggtc atgcggcggc tgcaccggcc
     8401 cgcgccgccg gactgcgggc ttccggcggt cgaggcggag ggcgcggcct tcgccgagca
     8461 cctggaccgg ttcccggggg acgatccgct ccccggcacc tggtcgagcg ggccgcgcgg
     8521 ctgttcgacg aactgtgcgc ggactccggc gaacggttcg tcctgcacgg cgacctgcac
     8581 cacgacaacg tcctgcgggg cggccgggag ccgtggctgg cgatcgaccc gcacggcctc
     8641 gtgggcgacc gcggctacga gatcgggccg gtgctctaca accccgaccc ggacgtgcgg
     8701 gacgagcggc tgctcggcct cgtgcccgcc cgcgtcgagc ggctcgcgga cggtctcggc
     8761 atgccggtgg aacgggccgt ggcgtggggt ttcgcgtcgt gcgtcctgtc ggaggtgtgg
     8821 gaggcgcagg gcggggagcc gggcgggcgg gcgctggacg tcgcgcgcct gctgctgccg
     8881 atgctgcccg cgtagcggtt caccagcgct ggcgtgcctc ctcggcccag ccggtgaggc
     8941 cgtcgaggtc gatccaggcg ccgtcgtcgg tgcgggcccg tccggtgaac gtcccgaagc
     9001 actggtgggt ctcgctgccg acgacgccga gttcggtctt cgagaccttc tcgtggaacg
     9061 ggtggaactc ggcccgcacc cgagggccgc cgatcgtcca ggggcggagc cggtcggtgc
     9121 ggtcgtagac ccagtcgagc tcgtcgccga tcttgtgcag gcgcccgttc acgaacaggg
     9181 cgttctccgt catgccggtg ccgtcggtcc actggccgcc gagctgcagg gccaggccgg
     9241 gcgcggcggc cgccgcccag ttccacgtca tccggtacgg ccacttgccg cgcccgtggt
     9301 cgaggacggc gaacgagtcg gcggcgtcca ccgcgacgtc gccggacggg agccgcagcg
     9361 tcccgtggac gggacggccc acgtccttca ccgtgtactg gaagcggttc gcggtccacg
     9421 gatcacgacg ccgagcgact cgtgcccgtc cggaacgggc accgtgaggt cgaggtcgac
     9481 gccgatcgcg ggcgcgaggg cgcgcagccg ggtgccgccc ggttccgcgc gggcgccgac
     9541 cgcgacgccg ccgccgcgca cggacgcggt gccctcgccg ctccggtcgg ggaaccgcgc
     9601 cccgagcgcg aacgggacga ccgcgtcccg gttcagctcc tcgccggtct cccggtcgag
     9661 gacgtacacg ccgtggacgc ccgcgtagtc gagcgaggac gcgacgagcc cgacgatgtg
     9721 gcggggcgtg acgatccccc agtactccca ccgtttggcg cggccccagc cgcgcaggtt
     9781 cgcggtgtgc agggggcggc gcgtccagcc gacggcggcg gggttgaggc gcccgtcggg
     9841 caggcacagg tcgacgggcg cggcgatctc tcgctcgggc atcccccgag gttatcgggc
     9901 gttcgccggg ctcgggcgtc cggtccgaca cgcacgtgat tcaacaagtc cataccaaga
     9961 tcagagtttt tcgggtgccg cgcgcgctca tctcactgtg gtgatcactg attcgccctg
    10021 gaacgtcgag gagcacgacc gggcgctggc acggctcgct gccggggaga acttcccggt
    10081 ggcggcacgg ctgctgccga agcggatccg cgccgacctg acggcggtgt acgggttcgc
    10141 ccgcctcgtc gacgacatcg gcgacgaggc gccggccgag cagcgcggca agctgctgga
    10201 gctggtggac gacgacctgg accgcgtgta cgggggcgcg acgccggagc tgccgcagct
    10261 ccgcaggctg gcgcgggccg tccacgcgcg gtcgatcccg gacgagccgt tccgccggct
    10321 cgtccaggcg aaccggcagg accagaccgt ccaccggtac gagacgtggg acgagctggt
    10381 ggcgtactgc cggctctcgg cggacccggt gggacggatc gtcctgcacg tgttcggggc
    10441 gtccgggcgg gggctggagg agtcgtcgga cctggtctgc acggcgctgc aggtgatcga
    10501 gcactgccag gacgtcgggg aggacttccg gcggggacgg gtgtacctgc ccgccgagga
    10561 tctgcggcgg ttcggctgca ccgacggcga cctggggcgg acgaggacgc cgacgcggct
    10621 gcgcggcgtc gtggcgctgg aggcggcgcg ggcccgcgac ctgctggacc gggggcgccg
    10681 ccgctgatgg cggggctgcc gggtgggcgc ggatcgccgt ggcgggctac acggccgggg
    10741 gcgggcgacg ctcgccgcgc tggcgcgggg ccgctacgac gtgctggcgc gcgcgctgcg
    10801 tccaggacgt gccgcgctgt tggccggttg ggcacgcgca ctggagaggg gtgagcgatg
    10861 acggtctcgg aggcgtgcga acggtccgag cgtgtggttg aggcgtatcg gcactgcgag
    10921 cgggtggtgc gtgaggaggc ccgcaacttc ggctacggga tccggctgat gcccgtcccg
    10981 aagcggcggg cgatgagcgc cgtctacgcg ttcgcgcggg gggtcgacga catcggggac
    11041 gggccggagc cggcgtgcgt ccggctcgac ctgctggacc ggtcgcgggg ccggatcgcg
    11101 gccgtgcgcg acgtcctgga gcaccgggcg gacgcggcgg tgctggaggg gcatccggtg
    11161 ctgacggcgc tcgcggacgc ggcggcccgc tacccgatcc cgctggaggc gttcgacgag
    11221 ctgatcgacg gctgcgagag cgacgtgcgg ggcgcggact acgagacgtt cgacgacctg
    11281 ctccagtact gccgccaggt ggcggggacc gtcgggcggc tgtcgctcgc gatcttcggc
    11341 acgcaggggc ggctgcggcg gaggcgctcg cggactccct cggcatcgcc ctgcagctca
    11401 ccaacatcct gcgggacctg cgcgaggacc ggctcgcggg acgcgtctac gtgccgaccg
    11461 aggacctcaa gcgcttcaac tgcacgctcg aactggacga ctcgggcatg ttcgtcgacc
    11521 cgccgtcgcg gctgaacgag ctggtggggt tccaggcaga gcgcgcgcgg gcctggtacg
    11581 cggaggggat gcggctgctc ccgctgctgg accggcgcag cgccgcgtgc accgccgcca
    11641 tggccgggat ctaccggcgg ctgctggaga acatcgcgga gcggcccgcg gccgcgctga
    11701 acacccgcgc gtccctgccg acgtggcaga aggcggtcgt ggcggcgcgc gcgctgacgg
    11761 gggtggagcg gtgagcgtcg tcatcgtggg aggcgggctg gccggcatca gcgccgcgat
    11821 agccctccgg gaatcgggcg tcccggtgac gctgctggag gcgcggccct ggctgggcgg
    11881 cgccacgcac tcgttcgagc ggggcgagct cagcgtcgac aacgggcagc acgtgttcct
    11941 gcgctgctgc accgcctacc aggggctgct gcagcggctc ggcgccgacc acctggtgga
    12001 cgtccaggac cggttcgacg tgacggtgct gcggcccggc gcggcggcgg cgcggctgac
    12061 ccggtcgcgg ctgcccggcc cgctgcacct gctgcccgcg ctggcgcgct acccgcacct
    12121 gacgcgcggc gagcggctgc gcgcgatgcg ggcggcggcc gcgctgcggc ggctggaccc
    12181 gaccgacgcc cggctcgacc agatcgcggc ggggccgtgg ctggcggcgc ggggccagcg
    12241 gccgtgggcg cgcgaggcgc tgtggggact gttcatcacg gcgtcgctga acgcggaggt
    12301 ggacgacgcc gcgctcgggc tgtcggcgat ggtgtgccgc cgcgggctgt tcggccgcgc
    12361 ggacgccgcc gacatcgggg tccccgtcgt cccgctggag gagctgcacg gcggcccggc
    12421 gctgcgccgc atcgccgaga tgggtggcac cgtccggctg aaggcgaagg tcgaggccgt
    12481 gaccaccgac ccgaaggtgg tggtggacgg cgtgccgatc gccgcggacg cggtgatcgt
    12541 cgcggtgccg cacgaggcgg ccgcgaaggt cctgcccgcc gaggcgctgc cggacccgct
    12601 gcgctggcgg gagctggact ccagcccgat cgtcaacgtg cacgtcgtct acgaccgtcc
    12661 ggtcatgggc gagccgttcg ccgccgcggt gggctcgccc gtccagtgga tcttcgaccg
    12721 gacgggcgtc agcgggctgc gggacggcca gtacctggcg gtctcgctgt cggccgccga
    12781 ccgctggatc gaccggccga ccgcggagct gcgggaccgg ttcgtcccgg agctggcgcg
    12841 gctgctgccc gccgcccggg gcgcccgggt gcgcgagctg ttcgtgacgc gggagcggcg
    12901 cgcgacgttc cggcagcgtc ccggcaccgg cgcggtgcgc ccggcggcag cgacgcgggc
    12961 cccgggactg ttcctcgccg gcgcgtggac cgacacgggc tggccagaca ccatggaggg
    13021 agcagtgcgc agcggcctga ccgccgctcg gctggtccgc cgccacctgg agggggtgag
    13081 ggaccggtga cgaccgttcc ggtttcgatg accgatgtcc gggggctggt cgacggggcg
    13141 ctgcgcgccg cggtgggccg cctcgatccg cgcacctacc gggtcgccgc ctaccacctc
    13201 ggctgggccg acgcggaggg gcacccgcgg gccgccccgg cgggcaaggc gctgcgcccc
    13261 gcgctggcgc tgctgtcggc gcgggcggcg ggcgcggcgc aggagagcgc cctgccgggc
    13321 gcggtcgccg tggagctgac gcacgcgttc tcgctcctgc acgacgacat catggacggc
    13381 gacctcaccc ggcggcaccg gcccgcggcg tgggccgtgt tcggcgaggc cgacgcgatc
    13441 ctggcgggcg acgcgctgct gtcgctggcc gtcgaggtgc tgctggaggc gcccgggcag
    13501 ggctcggcac gcgcggcgcg ggcgctgtcg gcggccaccc ggcggctcat cggcggccag
    13561 gcccgcgacc tggagttcga gtcgcgccgg accgtctccc tcgacgagtg cgtcgcgatg
    13621 gcgtcggaca agacggcggc gctgctggcc tgctcgtgct cgatcggcgc cgtcctggac
    13681 ggcgcgcccg agccgctgtg caccgcgctg gccgagttcg gcgccgacct cggcatcgcg
    13741 ttccagctcg tcgacgacct gctcggtgtc tggggcgacc cggagatcac cggcaagccg
    13801 gcgctgtcgg acctgcggtc ccgcaagctg tcgctgcccg tggtcgccgc gctgaacgcc
    13861 gggacggcgc agtcggagcg gctcgccgag ctgtacgcgg cgcccggctc cgacggtgcc
    13921 gacggcgacg cggacggcga gtccggggac ggcgcggagg acgcccggct cgaggagatg
    13981 gcgcggctcg tggaggcggc cgggggccgg gcgtgggccg aggccgaggc cgggcgccgc
    14041 atcgagcgcg ccgccgcgcg gatcacctcg gcggggctgc ccaccgcgat ccgcgccgag
    14101 ttcctgcaca tcgccgactt cgtcacggga cgggaccact gatgacgacg accgaaccga
    14161 tccatccggc accggaacag gcggcgccgg aacgggcggc ggccgaggcc gcgggggcga
    14221 tgcggacgcc cgccgaggcg ctcgccgccg cccgcgagca cctgctcgcc ctgcagtccc
    14281 ccgagggctg gtggaagggc gaactccaga cgaacgtcac gatggacgcc gaggacctgc
    14341 tgctgcgcga gttcctcggc gtccgcaccg aggacgacac ccgggagacg gcccgctgga
    14401 tccgctccca gcaggcggag gacggcacgt gggcgacctt ccacggcggc ccgtccgacc
    14461 tgtccaccac cgccgaggcg tacgtcgcgc tgcggctcgc cggggacgcc ccggacgagc
    14521 cgcacatggc gcgggcgtcc gcgttcgtcc gggctcgggg cggagtgccc gagacacggg
    14581 tgttcacccg cttctggctg gcgatgttcg gcgaatggtc gtgggacgac ctgccggtgc
    14641 tgccgccgga gatgatgttc ctgccccgct ggttcccgct gaacgtgtac gacttcgcgt
    14701 gctgggcgcg gcagacgatc gtcccgctga cgatcgtcgg ctcgctgcgg cccgtccgtc
    14761 cgctgccgtt cgacctgccg gaactgcggg ccgagcaccc cgcccgccgg tccggacggc
    14821 ggcgcgtgcc gggctgggac gaggcgttcc acacgctcga ccgggcgctg cacgtgtacg
    14881 agcggcgccc cgtccgtgcg ctccggcagg cggcgctgcg ccgcgccggc gagtggatcg
    14941 tggcgcggca ggaggcggac ggctgctggg gcggcatcca gccgccgtgg gtgtactcgc
    15001 tgatcgcgct gcacctcctc ggctaccgca acgaccaccc ggtcatgaag cgcgggctgg
    15061 acggcctgga gcggttcacg atccgcgacg cgaaggggcg ccgcctcgag gcgtgccagt
    15121 cccccgtgtg ggacaccgtc ctggcgatga acgcgctcgc cgacgcgggc gtccccggcg
    15181 acgacccggc gcagcggcgc gccgcggact gggtgctcgg cgaggaggtc accgggcccg
    15241 gcgactggtc ggtgcggcgc ccgaacctgc cgcccggcgg gtgggcgttc gagttcgaca
    15301 acgacgtcta ccccgacacc gacgacaccg ccgaggcgat cctcgcgctg gaccgcgtcg
    15361 gccacccggc cgccgaaccg gcgatcgagc gggccgtccg ctggatggcc gggatggcgt
    15421 cggcggacgg cgggttcgcc gcgttcgacg ccgacaacac ccgcgaactc tgccgccgcc
    15481 tgccgttctg cgacttcggc gaggtcatcg acccgccgtc cgccgacgtc accgcccacg
    15541 tcgtcgaggc cctcgcccgc cgcggcatgg ccgactcccg caccgtcaag cgggccgtcg
    15601 tgtggctgct gcgggcgcag gaacgggacg gctcgtggtt cggccgctgg ggcgcgaacc
    15661 acgtgtacgg gacgggcgcc gtggtgcccg cgctgatcgc ggcgggcgtc cggccgggca
    15721 aacccgcgat ccggcgggcc gtgcggtggc tcgaacggca ccagcggccc gacggcggct
    15781 ggggcgagga cctgcgctcc tacgacgacc ccggctggat cgggcgcggc gcgtccacgc
    15841 cgtcgcagac cgcgtgggcc ctgctggccc tgctcgccgc cggggagcgc gggccggccg
    15901 tcgaccgggg cgtccgctgg ctgatcgagc accagcggca ggacggcacg tgggacgagg
    15961 accacttcac cggcaccggt ttccccggcg acttctacat caactaccac ctgtaccggc
    16021 tggtgttccc cgtcagcgcc ctgggccggt acgtccggga ggcctgacat gggcatgcca
    16081 ctgcgccaga gcctgcgcgt cggcgggtac gtgctgaaga acaagctcgc ccgccgcgcc
    16141 aagttcccgc tgctcgtcga gctggagccg ctgttcgcct gcaacctggc gtgcgccggc
    16201 tgcggcaaga tccagcaccc ggcggacgtc ctcaagcagc ggatgccggt cgagcaggcc
    16261 gtcgccgcga tccgcgagtg cggcgcgccg atggtctcga tcgcgggcgg cgaaccgctc
    16321 atgcacccga agatcggcga actcgtgcgc gagctgatcc ggatgaagcg gtacgtgttc
    16381 ctgtgcacga acgccgcgct catcccgcgc aagatcgacc agttcgagcc gtccccgtac
    16441 ttcgcgtggg ccgtgcacat cgacggcctg cgcgaacgac acgacgcgtc cgtctgcaag
    16501 gagggcgtgt tcgacgaggc cgtcgccgcc gtccggatgt gcaagaagcg cggtttccgg
    16561 gtcacgacga acacgaccgt gttcaacacc gacaccccgc agaccgtcat cgacgtgctg
    16621 aactacctga acgacgacct gcgcgtcgac cagatgatga tctcgcccgc ctacgcgtac
    16681 gagaaggcgc ccgaccagga ccacttcctc ggcgtccagg agacgcggtc gctgttccag
    16741 aaggcgttcg cgaacggcaa ccgcaagcgc tggcggttca accactcgcc gctgttcctc
    16801 gacttcctgg aggggaaggt cgacttcccc tgcacggcct gggcgatccc gtcgtactcg
    16861 ctcaagggct ggcagcgtcc ctgctacctg atggacgacg ggtacgccga gacgtaccgg
    16921 gagctgatcg aggagaccga ctgggactcc tacggccggg gccgcgacga ccgctgcgcg
    16981 aactgcatgg cccactgcgg ctacgagccg acgtcggtgt tcgcgacgat gggttccctc
    17041 aaggagtcga tccgcgcgat gcgcgccgtc tgaccggcca ccaccggagc cccgcgccac
    17101 caccccgcgc ggggctcccc cgtatctcag gcggtcgacc ggcgcggggc gccggtcgac
    17161 cgcctggtta gggccccgcc ggggcacacg gtgcggcaca cggtgcggcg gccatccggc
    17221 ccacgtccgg ccggcgggcc gcccgcgcgg gccgcccgcg cggtgcggcg cacatccgcc
    17281 gggcgagggc ggcagacccg tgcggtcgga cgcccaaggt gacggtcgcg agggcggcgg
    17341 ggtcagagtt ggggggccgg ggtttcgggt ttcggggtgg tgtggagttc ggcgatgaca
    17401 tcgccgatcg cggcggtgag ggtgtcggcg tcgtcgacca gaccggggtc gagcgagacg
    17461 ccgaagcaca gctcgcggga gacgccgagg gcggcgacgg cgagcggggc gccgggcgcg
    17521 agcgggacga ccgggtagac ggccgcgagc ggggcgccgg cgaggcggag cgggccaccc
    17581 ggtccgggca ggctcgacac gatgccctgc aggaagcgct cgctgtaggc ggcgcgggcg
    17641 aaccgggcgt gcagcggcac cggcatcagc cgtccgacct gccgcatcac gaaccacgcg
    17701 gccagcgcgc gggtacccga ccgcagcacc ttgcagcggc gggcgatgtc ggcgagccgc
    17761 tccggctcgg ccatcgcccc gatcggcagg tcgaccatca cggcgctggt gtggttgccc
    17821 tccatcgcac cgccgggggc ccgcatcatc agcgggacgg cgacgcggca cgtcccgcgc
    17881 tcgttcccgc cgggacgggc gacgcggtgc aggccgcccg cgacggcgca gagcacgacg
    17941 tcggtcaccc ggacgccgtg ccggcgggac acgtcgcgga cgaggtcgag cggcaggtgc
    18001 agggtgccga agcggcgctc gggggtgccg gcggcgggca gccgggcggg cggggcgacg
    18061 tccacggcga gctgggcgag gccgatcgcg gtgccggccg cggcggtgag cgcggtgcgg
    18121 acccggccgc gcggcggccc ggcgggcgcc gggtcctgcg ggggctccat cagcgacgcg
    18181 gcctgcgcga cgacgccgac gccgtccgcg acgacgtggt gcatgaggaa cacgacggcg
    18241 gtgcggcccg gttcggcgcc gcgcacgagg aggatccgcc acagcggccg gtcgcggggg
    18301 aagggttcgg cctgcacgcg ggcgatgacc tcgcggagcc cgtccatccc ggcgacgtgg
    18361 tgctcggcga cgtgccagtt ccagtcgagg gccggatggt cgcgccagac gggccgccgc
    18421 cagcgtccgg cgccgtccgg gcgctggcgc aaccggggca gccggtccat ccgcccggcg
    18481 acgagccgga tcacgtcggc gcgctccacc gggtcgcggg aggtgtcgag catgatgacg
    18541 ccgccggtgt gctgcggcgc ccgctcggtc tcgacggcga ggaagaacgc gtccggggcg
    18601 cggacgcgtt cggccgacgg gcgggccagc cgttcggccg cgtacaccga cacggcgacg
    18661 agcgggacgg ccgcgacggc gtccacgagg tagtggttcg cggtcgccat gatcacgtag
    18721 ccggtgacga cgatgtggac ggtgttgacc gcctgcaccg accggtgggc gttcacccgc
    18781 gccagctcga caccgaccca cagcgtccac gccatgtgca gggacggcag cgcggcgaac
    18841 cggtcggcgt gctcgaccag cggcgacccc cacgaccccc aggtgccgcc gagccggacg
    18901 gtgtcgacga agccgaggtc gggcatcagc cgcggcggca tcaccgggta cagcgcgaag
    18961 cacgcgagcg cgatgacgtt gagcaggacg aacgcggtgc gggccgtccg gtaccggccg
    19021 gggtggcgca ggaacagcca gaccagcagt gcgagcgcgc tcacgacgta ggtgatcgcg
    19081 tactcgtagt tggccaggac ccgcaggacg gactggtccg cgagccactc gttgagcgcg
    19141 agctccacgt cgaggtgcag cacccgctcc agctcgtaca gcgtctcccc gtgtgcgcgc
    19201 gcgagccgcg ccctcggctc ctccggcagc atcgccacga gcaggtacag cgcgaacagc
    19261 gcgagcccca gcagcacctc cccgaaggcg tgggcgcggg cggcgtcccc ctcccgagtc
    19321 aggaccgcgt cgcgcgccgt cacggcgggt gtccccagca tctccccacg aaccgctgtt
    19381 acccaggttt tccgaggtca gacggccgcg tccggaatcg gggatcttgt cgccggacgg
    19441 tccggaacgg caacccgccc ggcttgaccg ggaatcttcg ggaacatcct ggcctttccg
    19501 tacgtcttcg atatatcgtt gtcgtatcgc gagaggtcat agagtgatct cagaaggtgg
    19561 tgaagaacat gcgtcacatg cacggaggtc catggagcag gagcgacgtg ccgggttccg
    19621 gcccgctgtt cggcggcggt cccggcttcg gcccgtgggg cccgcccggc ggattcggcc
    19681 ccggaggccc gggcccgcgc ccgccgtggg cgcacggccg gcgcggcggc ccgtgggggc
    19741 ggggcgccaa ggcgcgcaag gggaacgtcc gcgcggcgat cctcgcgctg ctcgccgagg
    19801 agccccgcaa cggctaccag gtcatccagc agatcgccga gcgcagcgag cacgcgtggc
    19861 ggccgagccc cggcgcggtc tacccggcgc tgcagcagct cgccgacgag gggctgatcg
    19921 ccgccgacga gaccggcggc cgccgcgcct accggctcac cgaggcgggc cgcgcgtacg
    19981 tcgaggagca cgcggacgag ttgcgcgagc cgtgggcggc gatggcctgg gacttcggcg
    20041 agggcgtccc cgaactgttc aagcaggccg cgcagacggg agccgcggtc atgcagatcg
    20101 tccactcggg ccgtcccgag cagctcgacc gggcgcggga cgtcctgtcg acggcccgcc
    20161 gcgacctgta ccggatcctc gccgacgccc ccgccggcag cgacgacgcg gaccccggcc
    20221 cggacgcccg ggaggggtca tgaccgacga actccgcatc ggcgacgccg agcgggacgc
    20281 ggtcgtcgtc gcgctgcacg accacttcgc ggcgggacgg ctggaccgcg cggaactcga
    20341 cggccggatg gacgccgcgc tcgccgcgaa gacccgcggc gacctggccg cgctcgtccg
    20401 cgacctgccg ccgccgcacg gcctgcccga ggccgcgagg gcgcggcccg cgcccgtccc
    20461 cggtcccggg ccggcgccgt gggggcgccc gggcccgatg tacggcggcc cgcaccaccc
    20521 gcggcaccgc caccggcacc acatgcaccc gcaccaccac ggcccgcccg gcccggcgtt
    20581 cccgctgctg ctcgccgtct tcctcgtcct gacgttcacg gtcggcgcgg gcaccgggct
    20641 cctcgccgtc ctcggcatcg cgatggtggc gtggctcgcc cgcgccgccc gactcgccgc
    20701 gtccgtccgc cggtcctagg cggccggaag gcgcgtgcag ggctccggca cggcgtcgcg
    20761 gagggcccgc agcccgcgtt ccaccagcgg gttgccgcgc cctccgcgcc gcacgcacgt
    20821 cagcaggcgg cgccgcggca ccgacgggcc cgccagcggc acccggacgg ccccctcccc
    20881 cggcccgccg accaggcgcg ggaccagcga caccccgagc ccggcggcga ccagcgccca
    20941 gatcaccgac caggtggccg tggagtgctc gacgcggggc gtgaacccgg cggcggcgca
    21001 gtgggcgagc agccggtggt ggtggtcgca gctctcgggc cggacgctga tccacggctc
    21061 ggccgcggcg tcctccaggc gggcgattcc ccgcgcggcc agcgggtggc ccgccgggac
    21121 gatcaggtcc atcgcctcct ccagcagcgg ctcccggtcg aagcgggggt cgccgggcgg
    21181 gggcgcgtcg gcggacggct cgatgaccgc gatgtcggtg tcaccggcgg ccagcagggc
    21241 catcgcctcg gccgtgtcgc actcgcggat ctcgatcggc aggcgcggat ccgcgcgccg
    21301 cagccgtccg gcggccgggg cgatcagccc gctgacggcc gtcgtgaacc cgcacatgcg
    21361 cagcggcccg gcggcgcccg tccggtgcga ctcgaggtcg gcgaccgtct cctcccagcg
    21421 ggccaggagc gcgtcggcgt gcccgatcag cacgtgcgcc gccggtgtga gccgcacccg
    21481 gcggccctgc ggctccagca gcggcacctt cagctcgcgg ccgagttcgc gcaggtggtg
    21541 ggagacggcg gacggggtca ggtgcatcgc ctcggccgcg gacgtgaccg tcccgtactg
    21601 gtggacgagc cgcagcatgt gcaggcgccg gaggtcgatc atgcaaccat gttgcacggt
    21661 ctagtggaga aatgtgaaat ggacggcaac gttcatgcct gtgcagactg ccgtcatgac
    21721 ccagtgcagc acgacggaac agcggcccgt gatcgtctcc cggcacctca ccagcgacgg
    21781 cgtcgtcctg tggacgcgct gctcgtgcgg ccgcctgcgg atggacctcg tgccggacgg
    21841 gcccggcggg tcgcgcctga ccgccgggcc ctgcccgcac gtccccgccg gctagatcgt
    21901 tgatgggggt tgttgagtgc ctcggtcagt ggtcataggc gatcagtgac cgcttgaccg
    21961 gggcgccgat cagccagttg tgccagatca cggcgttgag ggcgcagatg cgctggcaca
    22021 ggcgcgtcca gagtccctcg gtggtgcgtg cggcgtggcg ttccagtccg agctggttct
    22081 tcagggtcca gatgacggcc tcgatgcgct ggcgcagcca ggccgggaac accttgacag
    22141 gcggctcggg ctcgtcctgg cgcaccggcc ggatcaggag gtggcccagg ccggcggcgg
    22201 tcttctccac cccggctccg gcgaatccct tgtcgcacac gatcgggcac ggacccggcg
    22261 cgggcggccg ggcgtgcagc aggtggatcg cctgcttgcg ctcgtccagt tccttggggt
    22321 gggccacgct gaaagagcac actgcgcctt cggggtggtg atcagcatga gcttggctcc
    22381 ccagtagaag gcgtggtggg acttgtccat gccgtagccg gcgatctcgc ccagcgcgga
    22441 gcggtgcacg gtggtgcggg aggcgccgca gcgcagcggg gtgccgtcca tcagccgcag
    22501 ccggtcgtgc caggacggga tccggcggac cagccacgcc gctgcggccg ccagggcggg
    22561 ggcggcgtcg cgcaggtgcc ggttgtactc ggactggccg ggcagccggg ggaacaggtg
    22621 cccgatccgt gcgggcgcgg tccgcagcca ccggcgctcg gaatcgcacc cgagcaggac
    22681 ttgggcgatg gcgacgcaga ccagctcggc gtcgttgagg gtccgggcgg ggccgcgtct
    22741 gcggggccgg tcggccgatc gcaggacgtg gtcgtccaga tggacgtaga gtgcggtcag
    22801 aagggcgtcc aggtttgtct tcacacactg atcatgggcg cccttcgcca tgcccgccgc
    22861 cggttcggca aacccccatc aacgatctag cggagggcgg cggcttcggc ggccagcttg
    22921 cggatccgct cccagtcgcc ggagcggacg gcgtccgccg gggtcagcca cgtgccaccg
    22981 acgcagccga cgttcggcag cgcgaggtag tcggcggcgt tgcccggctt caccccgccg
    23041 gtcgggcaga accggacctg cgggagcggg ccgttcagcg ccttcaggta cgggatgccg
    23101 ccggcgggct cggccgggaa gaacttcatc gcggtgacgc ccgcctcgag gagcgcgacg
    23161 gcctccgacg cggtcgcggc gcccggcagg aacggcaggc cggtcgccgc catcgcggtc
    23221 cggagccgtt cggtgcagcc ggggctgacg aggaagcggg ccccggcggc ggccgaacgc
    23281 tcggcgtcgt ccgggcggac gaccgtcccc gcgccgacga ccgcgtccgg cacctcggcg
    23341 gcgatccggg tgatcgcctc gatcgcgacc ggcgtccgca gcgtcacctc gatcgccggg
    23401 agcccgcccg cgacgagcgc gcgcgccagc ggcacggcgg cgtcggcgtc gtccaggacg
    23461 acgacgggga tgacgggcgc gaggtcgaac aggtcttcgg cgttcaagcg gactccaagg
    23521 gtcgtgcggg ttcgggcgcg gtctgcgcga gccgcatggc cgcgccgacc agggcggggc
    23581 cgggatggac gatcagcgcg gtcgggatcg cgcgcaggta cccctcgacg ggaggtttcc
    23641 cctcgaaccg ggcgcggaac gcgctgtcct tcaggacgcc ggcgatgcgc gggaggatcc
    23701 cgccgccgag gtagacgccg ccggtcgcgc cgatcgtcag cgcgacgttg ccggcgagcg
    23761 agccgagcag ctcgcagaac atcgcgagcg tgcgggcaca gcgggggtcc cgcgatcccg
    23821 gccgctgcgc acgctcgacg atcgccgcgg gcgtgaccgg ctcgggcggg acgccgtcga
    23881 tgatcgcgag gtaccggtgg atgcgggcga ggccgtcgcc ggacagcagg tattcggcgg
    23941 tcgcggcgcc gcgctcggcg cgcagcagcc ggacgacctc gccctcgagg tcggtcccgg
    24001 cgggcgcgtc gacctggccg ccctcccccg gcagcggcac ccagccgccg ccgggcaccg
    24061 ggacgagccc gccgacgccg agaccggtgc cggggccgac gaccgcgacc ggcccgtccg
    24121 ccgccgggta ccggtcgccg accgggacga ggtcgtcggc ggcgaggcgc ggcagcgaca
    24181 tcgcgagccc cgcgaagtcg ttgacgatct ccaggtgcgg cacgccgagg cggtcgcgca
    24241 cgtccccggg ggtgccgacg ggccagcccg cgttcgtcag gtggaacgtc ccgccggtga
    24301 cggggcccgc gaccgccagg cacgcggcgg acgggcggac gcccggggcg taccgggaca
    24361 ggtaggccag cgcggcgtcg gcgaggtcgg cgtgctcgcg ggtgggcagc gcgcggacgt
    24421 cgcggggcgc gccgtccggg ccgtccacga gcgcgaaccg cgcgttcgtc ccgccgatgt
    24481 cgccgaccag ccacggggcg gtcatccgaa caccccggcg ccgcgctcgg ccgggccgac
    24541 cgccgcgcgg aaggccgcga acagctcgcg tccggtgccc gaccaccggt ccgggtcggg
    24601 cacgcccccc tccggctccc gcgcggcgaa ctcctcgtcg ggcaccagca cctcgaggag
    24661 gcccttgtcc gcgtcgagcc gcaccacgtc gccgtcccgg acgcgcgcga gcgggccgcc
    24721 cgcggccgcc tccggcgtcg cgtggatcgc cgcgggcacc gcgcccgacg cgcccgacag
    24781 ccgcccgtcg gtcaccagcg cgacccggtg gccgcggtcc tgcaggacgc cgagcggcgt
    24841 gatcagccgg tgcagctcgg gcatgccgtc ggcgcgcggg ccctgcagcc ggacgacggc
    24901 gacgacgtcc cggtcgagtt ccccggcggc gaacgcgtcc tgcagctcct cctgcgagcc
    24961 gaacacgcgg gccggggcct cgaccgtccg gtgctcgggc ttgaccgccg acaccttcac
    25021 gacggcgcgg cccaggttgc cgcggaccgt ccggagcccg ccgtgggtgt cgaacggttc
    25081 cgcggcggga cgcagcacgt ccgcgtcgcc ggtggtcgcg ggaccgtccg cccacaccac
    25141 ccggccgccg tcgaggcgcg ggactgtgcg gtactcggcg aggctcgcgc cgccgaccgt
    25201 gcgggcgtcc tcgtgcagca gcccggcgtc gatcagctcg ccgatgagga acgcggtgcc
    25261 gcccgccgcg tggaagtggt tgatgtcggc ggtgccggac gggtagagct gcgtgagcag
    25321 cggggtcacc tgcgacagct cgtcgaagtc gtcccaggtc agttcgatgc ccgcggcggc
    25381 ggccatggcg ggcaggtgca gcgtgtggtt ggtggagccg ccggtggcga gcagcgcgac
    25441 gatcgcgttg gcgaacgccc gctcgtccag catctcgccg accggggtgt actcgtcggc
    25501 gaggtcggtg atccgcagga cgcggcgtcc ggcggcggcc gtcaggccct cgcgcaggtc
    25561 ggtgcccggc gggacgaagc tcgcgcccgg caggtgcagg cccatgacct ccatgagcag
    25621 ctggttggag ttcgcggtcc cgtagaaggt gcaggtgccg ggcgagtggt aggacgcggc
    25681 ctcggcggcg agcagctcgt cacggccgat ctccccggcc gcgtagcgct tgcggacctt
    25741 ggccttctcc gcgttcggca gcccggaggc catcggtccg gccgggatca ggatcgccgg
    25801 caggtgcccg aacgacagcg cgccgatcac cagcccgggg acgatcttgt cgcagacccc
    25861 gagcagcagc atgccgtcga acatgtcgtg cgagagggcc accgccgtcg ccatcgcgac
    25921 gacgtcccgg ctgaacagcg acagctccat gcccgcgcgg ccctgggtga tcccgtcgca
    25981 catcgccggg acgccgcccg cgaactgcgc ggtgccgccg cccttgcgga tcgcggcctt
    26041 gaggacgtcc gggtagtcct tcagcgg
//
