LOCUS       NZ_CP031599            25977 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Roseovarius indicus strain DSM 26383 plasmid pRIdsm_01, complete
            sequence.
ACCESSION   NZ_CP031599
VERSION     NZ_CP031599.1
KEYWORDS    RefSeq.
SOURCE      Roseovarius indicus
  ORGANISM  Roseovarius indicus
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Roseobacteraceae; Roseovarius.
REFERENCE   1  (bases 1 to 450820)
  AUTHORS   Vollmers,J. and Petersen,J.
  TITLE     Genetic Globetrotter - A new plasmid hitch-hiking vast phylogenetic
            and geographic distances
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 450820)
  AUTHORS   Petersen,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2018) Single Cell Genomics, Leibniz Institute
            DSMZ, Inhoffenstr. 8, Brunswick 38126, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: DSMZ_RIdsm
            Expected Final Version            :: yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RS; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728195.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 05:52:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,061
            CDSs (total)                      :: 6,008
            Genes (coding)                    :: 5,925
            CDSs (with protein)               :: 5,925
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 24 of 83
            Pseudo Genes (incomplete)         :: 57 of 83
            Pseudo Genes (internal stop)      :: 17 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 179966
            Orig. end                         :: 205943
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031599.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25977
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="1"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     cand_cluster    1..25977
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..25977
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:15977](+)"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..15977
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     gene            251..1105
                     /locus_tag="RIdsm_RS27185"
                     /old_locus_tag="RIdsm_05469"
     CDS             251..1105
                     /EC_number="1.6.5.2"
                     /GO_function="GO:0016655 - oxidoreductase activity, acting
                     on NAD(P)H, quinone or similar compound as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1199: NmrA family
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009503105.1"
                     /locus_tag="RIdsm_RS27185"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05469"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_057817081.1"
                     /transl_table=11
                     /translation="MITVFGATGTTGAPLVDTLMAKGATVRAVTSDPFKLDALKAKGCE
                     AVAADFTDPAALARACDGAEKIYLVTPAHLDMRQWKANVIEAAKAAGVRHIVVATGLGA
                     SPKAGLTFGKWHSETQELLKQSSLDWTFVQPTYFMQNLLWQAGNIAKDAVYYDDVGGPV
                     AWIDARDIADVAAEALTAPGYEGKALGLTGPEALAGDDIAALLSGVTGRTVSCVSLSAE
                     DARAGMVAGGMQDEVAGAMVELASIAPRGYLAGIETTVSEVLERPARRFADFVTENRDA
                     FVK"
     gene            1089..1814
                     /locus_tag="RIdsm_RS27190"
                     /old_locus_tag="RIdsm_05470"
     CDS             1089..1814
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009503104.1"
                     /locus_tag="RIdsm_RS27190"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05470"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_057817083.1"
                     /transl_table=11
                     /translation="MLSSSNLMAAPLYLELAPPEEAATEIDHLFVFRDTGVLSGGGRGR
                     FATDLFTLSVTRDHSGGARVSLAPPRSGFTLRPRPFHGVVAGLRLSSRPKHLPDSKGLD
                     MLAAELARVQIGDGDLPALIAVLDGLARDLRFAAPTGAYSDRTKRRKVRAETGVSRRRL
                     ATLRRFRRALGQLASKTLPLSDLALDAGYYDQSHLSAACRIFADKPPGALRALSIPRRF
                     DLSLQDTRLKDRLRLVIDE"
     gene            1836..2291
                     /locus_tag="RIdsm_RS27195"
                     /old_locus_tag="RIdsm_05471"
     CDS             1836..2291
                     /EC_number="3.1.2.-"
                     /GO_function="GO:0047617 - fatty acyl-CoA hydrolase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1144: thioesterase superfamily protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009503103.1"
                     /locus_tag="RIdsm_RS27195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05471"
                     /product="PaaI family thioesterase"
                     /protein_id="WP_057817085.1"
                     /transl_table=11
                     /translation="MTQFKPKNPDYDARVRDSFDRQKVMNTLGISIAELSPGRIVLEMA
                     HEDALTQQHGFLHAGIVSTALDSACGYAAFSLMPAEAAVLTAEFKINLLNPADGERFRF
                     VADVVKPGRTLTICEARAYAVKGQDEKLVATMTGTLMALVGRAGVAG"
     gene            complement(2356..2922)
                     /locus_tag="RIdsm_RS27200"
                     /old_locus_tag="RIdsm_05472"
     CDS             complement(2356..2922)
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011270027.1"
                     /locus_tag="RIdsm_RS27200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05472"
                     /product="flavodoxin family protein"
                     /protein_id="WP_057817087.1"
                     /transl_table=11
                     /translation="MTKVAIVYYSGYGHTDVQAKAVAEGAKGVDGTEVNLLKLPDDGEL
                     DDAAWAALDAADAIVYGSPTYMGGPAWQFKRFADASSKPWFTQNWKDKIAGGFTTSATV
                     NGDKFSTIQYFITLSQQHGQLWCGVGLMPSNTKADGPEKLNWTGGYSGLLAIAPSDSAP
                     EEYPTGGDLDTARAYGKRLAEVASR"
     misc_feature    complement(3061..3075)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 22.51"
                     /tool="antismash"
     misc_feature    complement(3069..3082)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 17.05"
                     /tool="antismash"
     misc_feature    3070..3085
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.34"
                     /tool="antismash"
     misc_feature    complement(3116..3131)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            complement(3153..4691)
                     /locus_tag="RIdsm_RS27205"
                     /old_locus_tag="RIdsm_05473"
     CDS             complement(3153..4691)
                     /NRPS_PKS="Domain: AMP-binding (16-409). E-value: 2.8e-76.
                     Score: 248.7. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS27205_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002: AMP-dependent synthetase and ligase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009803508.1"
                     /locus_tag="RIdsm_RS27205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05473"
                     /product="AMP-binding protein"
                     /protein_id="WP_057817089.1"
                     /sec_met_domain="AMP-binding (E-value: 6.8e-87, bitscore:
                     286.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTEVSRAGRADLYSIFRTRAQDCAGDLAIEDGSKRLSYAELLGR
                     VDRLAAVFLARGVAPGDRIAILSHNRSEYLEVELAAAGIGAIVACLNWRLAPDELWHCI
                     DLVEPVLAIVEPDFSEMYHAVASTPCLTIGPDLETAIAGAEQDPRIGTMVDDPEAGLTI
                     LYTSGTTGLPKGALISHRAHIARSMAFAAQLALDPCDGFIAWAPMFHMASTDHALATVL
                     RGGTVVMVDGLLPAVINEALSRHRIGWFVMMPGALDAFIAERRANPLPLKGIKVCGAMA
                     DLVPPHQIAELTALLDTPYLNSFGATETGLPPGTADLIAPGVTPDRLSKRISAFCEVRL
                     VDPDDRDVADGTPGEMAVRGPTLFSGYWNADDTNARDFRNGFFHMGDLFRRNADGSLDF
                     VDRAKYLIKTGGENVYPAEIERVLLSHPDVIDAAVVRAFDAKWGESPVAFVAFDDDGPD
                     AEALLNLCRESLAGYKRPREIRFIALEDFPRSTSGKIQHHMLEIRIADEKARSQ"
     aSDomain        complement(3465..4643)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS27205_AMP-binding.1"
                     /evalue="2.80E-76"
                     /label="RIdsm_RS27205_AMP-binding.1"
                     /locus_tag="RIdsm_RS27205"
                     /protein_end="409"
                     /protein_start="16"
                     /score="248.7"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="FRTRAQDCAGDLAIEDGSKRLSYAELLGRVDRLAAVFLARGVAPG
                     DRIAILSHNRSEYLEVELAAAGIGAIVACLNWRLAPDELWHCIDLVEPVLAIVEPDFSE
                     MYHAVASTPCLTIGPDLETAIAGAEQDPRIGTMVDDPEAGLTILYTSGTTGLPKGALIS
                     HRAHIARSMAFAAQLALDPCDGFIAWAPMFHMASTDHALATVLRGGTVVMVDGLLPAVI
                     NEALSRHRIGWFVMMPGALDAFIAERRANPLPLKGIKVCGAMADLVPPHQIAELTALLD
                     TPYLNSFGATETGLPPGTADLIAPGVTPDRLSKRISAFCEVRLVDPDDRDVADGTPGEM
                     AVRGPTLFSGYWNADDTNARDFRNGFFHMGDLFRRNADGSLDFVDRAKYLIKT"
     CDS_motif       complement(3564..3644)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RIdsm_RS27205_0002"
                     /evalue="4.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="RIdsm_RS27205"
                     /protein_end="376"
                     /protein_start="349"
                     /score="19.0"
                     /tool="antismash"
                     /translation="DGTPGEMAVRGPTLFSGYWNADDTNAR"
     CDS_motif       complement(4152..4205)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RIdsm_RS27205_0001"
                     /evalue="5.10E-07"
                     /label="NRPS-A_a3"
                     /locus_tag="RIdsm_RS27205"
                     /protein_end="180"
                     /protein_start="162"
                     /score="22.2"
                     /tool="antismash"
                     /translation="ILYTSGTTGLPKGALISH"
     gene            complement(4719..6719)
                     /locus_tag="RIdsm_RS27210"
                     /old_locus_tag="RIdsm_05474"
     CDS             complement(4719..6719)
                     /EC_number="1.3.1.34"
                     /GO_function="GO:0008670 - 2,4-dienoyl-CoA reductase
                     (NADPH) activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:0071949 - FAD binding [Evidence IEA]"
                     /GO_process="GO:0033543 - fatty acid beta-oxidation,
                     unsaturated, even number, reductase/isomerase pathway
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1217: NADH:flavin oxidoreductase/NADH oxidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017562879.1"
                     /locus_tag="RIdsm_RS27210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05474"
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="WP_057817092.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.1e-26, bitscore:
                     88.6, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 1.1e-08, bitscore: 29.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSPIRAGQHTLRNRVIMGSMHTRLETEPDGIAKQIAFYAERARG
                     EAALLVTGGFSPNAEGIFDPEGPRIDDPEEALGLRPICEAVQAEGSLICAQLLHAGRYA
                     KIEGCVAPSPIRAPINRFIPREMTEADILRTIEDFAVAAANAQAAGFDGIEIMGSEGYL
                     INEFTVTHTNKRQDDWGGSAANRHRFPVEIVRAVRERCGPDFLVIYRISAADLVEGGAP
                     ADEIAALARKIEAAGADILNTGIGWHEARVPTIAYPVPRGAWRKAAANVKAAVSIPVVA
                     SNRINTPQLAEDILASGDADMISMARPFLADPHFVKKTREGRSDEINTCIACNQACLDF
                     IFSDRPVGCLVNPRAGRETEFRDTPTDTPKKVAVVGGGAAGMATAAEAARLGHDVTLFE
                     AQDKLGGQLNLARAAPGKDEFDETLRYYAGQMQKHGVTQRLGQRAEASDLEGFDHVVIA
                     TGVTPRIPDLPGIDHPSVATYAEILSGDREAGDRVVVMGAGGIGHDVAEFLVTKPAETA
                     NSDVFCETWSVDPEFVSSGALAGDPLAPKPSRRKVVMLQRKTAKPGAGLGVSTGWILRN
                     ALRKHGVEAMGGVTYEHIDDAGLHIVADGMPKVIAADTIVLCTGQEPERALAQELTARS
                     VPVTMIGGAKEAAELDALRAIDEGVRLAQGL"
     misc_feature    6798..6815
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.55"
                     /tool="antismash"
     gene            6846..8027
                     /locus_tag="RIdsm_RS27215"
                     /old_locus_tag="RIdsm_05475"
     CDS             6846..8027
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009803510.1"
                     /locus_tag="RIdsm_RS27215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05475"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_057817094.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.4e-25, bitscore:
                     85.0, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.3e-19, bitscore:
                     65.1, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 1.1e-39, bitscore:
                     130.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFQPTDDQKAFRDTAKRFATEKLAPTYQERANGHTFDRALIKEM
                     GALGLIGADLPEEFGGLGESSVTSGLIVEEIAYADFNASYVQLLGSLMGGMVAKHASKD
                     IASEWVPKVVSGDAVIGLGLTEPRGGSDAANLILKAEKSGNGWRLNGEKTSMSFASQAD
                     AAVVFARTGDPDGGSRGVSAFFVDLNQEGIKRTHFDDIGTKPVGRGSVFFDDVFVPAEN
                     MMAEQDRAFGTIMAGFDYSRALIGLECLGAAQASVDETWAYVQEREAFGAPIVQYQGVS
                     FPLAEAETQLTMMRQLCYYTLDLRDRGLPHTSQAAMCKWYLPKTACEILHQCLILHGHY
                     GYTTDLPHHQRYNDVLGLQIGDGTAQIQKLVIAREKVGRMALQYDKKAKGAAK"
     gene            8024..8803
                     /locus_tag="RIdsm_RS27220"
                     /old_locus_tag="RIdsm_05476"
     CDS             8024..8803
                     /NRPS_PKS="Domain: ECH (11-251). E-value: 2.9e-54. Score:
                     175.9. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS27220_ECH.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1023: enoyl-CoA hydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009803511.1"
                     /locus_tag="RIdsm_RS27220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05476"
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="WP_057817096.1"
                     /transl_table=11
                     /translation="MSDPILVTSEGNTGIIELARPEKFNCLSLEVHERISVARAEFEAN
                     PAIRAILIRAQGKHFCTGADLVEVKGKLNDSAALDHFIAFGMNNLRALETSSLPVVVAV
                     QGLCLAGGIELMLACDVCFAAESAQFGDQHAQFGLIPGWGGSQRLTRLMGQRRALDLMF
                     SARWLKSDEAKEAGLVNYIVPDADLHKSALEYCEKIATRSRPGIAEMKRLAREGADLGV
                     DQQMRLERDAAVRALPSDDVAEGLDAFENRRAPRFKA"
     aSDomain        8057..8776
                     /aSDomain="ECH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS27220_ECH.1"
                     /evalue="2.90E-54"
                     /label="RIdsm_RS27220_ECH.1"
                     /locus_tag="RIdsm_RS27220"
                     /protein_end="251"
                     /protein_start="11"
                     /score="175.9"
                     /tool="antismash"
                     /translation="NTGIIELARPEKFNCLSLEVHERISVARAEFEANPAIRAILIRAQ
                     GKHFCTGADLVEVKGKLNDSAALDHFIAFGMNNLRALETSSLPVVVAVQGLCLAGGIEL
                     MLACDVCFAAESAQFGDQHAQFGLIPGWGGSQRLTRLMGQRRALDLMFSARWLKSDEAK
                     EAGLVNYIVPDADLHKSALEYCEKIATRSRPGIAEMKRLAREGADLGVDQQMRLERDAA
                     VRALPSDDVAEGLDAFEN"
     gene            8813..9973
                     /locus_tag="RIdsm_RS27225"
                     /old_locus_tag="RIdsm_05477"
     CDS             8813..9973
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009819984.1"
                     /locus_tag="RIdsm_RS27225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05477"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_057817098.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 4.5e-22, bitscore:
                     73.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 5.4e-20, bitscore:
                     66.3, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 5.6e-32, bitscore:
                     105.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDFTLNDEQRQIYEYGGQLAQKFDNDYWLRHARRHEFPHEMFRQI
                     ADDGFLGIMVPEEYGGAGLGMTEMALFMEGTANHGIPLLMMVVGPTMSLAHIASHGSEF
                     HKKELLPAACRGDIQFCFAITEPGAGSNTMKATTLAKRRGNRFSLSGEKTFITGAEVAD
                     YCLVVARTKPHTEVSRKTDGFTLFAVDLKKKGVDKQRVKISIPLPEEQWTLFFDEVDLG
                     PEDVVGEVDEGFSILFDSLNPERIILAALCCGIGRFALNKGVAYASERNVFGQPIGAHQ
                     GVQHPMAKAHTAVEMASLMTRRAAWEFDNKLPAGASSNMAKYAAAEAGIEAVDAALQAH
                     GGSGFTEDTGLYEMYPLVRLLRTAPVNRELCLSFIGEKVMGLPRSY"
     misc_feature    10001..10013
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.5"
                     /tool="antismash"
     gene            10001..11392
                     /locus_tag="RIdsm_RS27230"
                     /old_locus_tag="RIdsm_05478"
     CDS             10001..11392
                     /NRPS_PKS="Domain: AMP-binding (90-360). E-value: 3.8e-11.
                     Score: 34.1. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS27230_AMP-binding.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009504381.1"
                     /locus_tag="RIdsm_RS27230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05478"
                     /product="AMP-binding protein"
                     /protein_id="WP_057817100.1"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-07, bitscore:
                     23.8, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQFGMRFRREDAADKVNDRFWHTIEGTPLDEVRRIQEERLRDQMA
                     YLKANSTFYQEKFAEAGVDFDDIRTIEDLQKLPYTYKTEIRESLAAEPPFGKHRAAPMS
                     EIIQMQASSGTTGSPSYVALTESDAEMWHEMTARCFFANGVRPGDMVLHAFSLAKGFVG
                     GIPVMQGLQYMGTIDVPVGADGGAERLLRACADTRPRCVVGAPNFVLHLAEKAPEVLGC
                     KASELGIERVIVGGEPGGGIPAIRAKIEKAWGAKCTEMLGGTDLGVTYWAECDAQSGMH
                     MVNMDYVITELLDPESGEIIPWEKGAEGEMIYTALGRQASPLVRFRSGDYIEVIDTECS
                     CGRTGPKIRCTGRTDDMLIVRGANVFPSAINSIITEMVPDTNGVMRIVADFEGHTTQGA
                     LTVIVERGPDRDPADDVALKKKIEQRLRDSLVFKADVHLVAADTFEKPGAAKVAFVLRK
                     YPDLP"
     misc_feature    10046..10057
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.59"
                     /tool="antismash"
     aSDomain        10271..11080
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS27230_AMP-binding.1"
                     /evalue="3.80E-11"
                     /label="RIdsm_RS27230_AMP-binding.1"
                     /locus_tag="RIdsm_RS27230"
                     /protein_end="360"
                     /protein_start="90"
                     /score="34.1"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="AEPPFGKHRAAPMSEIIQMQASSGTTGSPSYVALTESDAEMWHEM
                     TARCFFANGVRPGDMVLHAFSLAKGFVGGIPVMQGLQYMGTIDVPVGADGGAERLLRAC
                     ADTRPRCVVGAPNFVLHLAEKAPEVLGCKASELGIERVIVGGEPGGGIPAIRAKIEKAW
                     GAKCTEMLGGTDLGVTYWAECDAQSGMHMVNMDYVITELLDPESGEIIPWEKGAEGEMI
                     YTALGRQASPLVRFRSGDYIEVIDTECSCGRTGPKIRCTGRTDDMLIV"
     gene            11389..12996
                     /locus_tag="RIdsm_RS27235"
                     /old_locus_tag="RIdsm_05479"
     CDS             11389..12996
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009803514.1"
                     /locus_tag="RIdsm_RS27235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05479"
                     /product="carboxyl transferase domain-containing protein"
                     /protein_id="WP_057817102.1"
                     /transl_table=11
                     /translation="MTKMKSLLDTASDDFRANDVSYREKVDELHALRLKQRVGGPEMAR
                     KRHMDKGKILPRERIERLIDPGTPFLELGELAGLNKYEGVPPGAGIITGIGVIEGRQCM
                     IIANDATVKGGTYFGMTSRKHVRAQKIAWKNRLPVITLVDSGGAFLPDQENIFPDEGQF
                     GSIFHQQIGMSGDGVPQIAVVMGPCTAGGAYIPALCDEVVIVRGQGFMYLGGPELTFAA
                     TGEKVEAEELGGGKMHSSVSGVTDHLAEDDAHALAITREIVSHLGEKPLPRKTPETPRA
                     PAYPVEEIYGLVSRDPKVPTDNREILARLLDDSDFHEFKPLYGDTIMTGWGRIHGHEVG
                     ILANTGVLFVEAALKATHFINLCVQRDIPLLFLADVNGFMVGREVEQMGIAKAGAKMIT
                     AMSSARVPKFTIITGGSYGAGYLAMLGRPFQPDAMFAWPTGRSAIMGPEQAASVLAQVR
                     AQINEREGKSWTPEEEEAFKAPIRKEYEDFQGAYNFASNLWIDSVIEPCETRDVMALML
                     DVTSRRPKVDTNFGVFRM"
     gene            13058..15013
                     /locus_tag="RIdsm_RS27240"
                     /old_locus_tag="RIdsm_05480"
     CDS             13058..15013
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP-grasp"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1090: acetyl-CoA carboxylase biotin carboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009504378.1"
                     /locus_tag="RIdsm_RS27240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05480"
                     /product="biotin carboxylase N-terminal domain-containing
                     protein"
                     /protein_id="WP_236553338.1"
                     /sec_met_domain="ATP-grasp (E-value: 2.5e-09, bitscore:
                     31.8, seeds: 20, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARTARASGITPVGVHSQADANALHVRKIGKSVCIGAGPASESYL
                     KIDAVIAAAQSVGADAIHPGYGFLAENPDFARAVEAAGMIFMGPTPETLERFGDKASAK
                     EAAVAASVPVISGAEGAWSDPEQIAEEVRQMGLPVLLKAVGGGGGRGQRLVSDETTLVE
                     DIEGALREAKSTFGSEGLLLERFLPEARHVEVQIAGDGKGHVVHLFERDCTLQRRHQKV
                     IEEAPAWGLYRSLLGDIAHDAVRLGEALDYRGLGTVEFLVAGDEYFFLEVNPRIQVEHP
                     VTEAITGLDLVALHLRIAEGAGLGLVQDDLKINGHAVEARLYAEDPAMQFAPSTGTLTT
                     LSLPSGLRIDSGVEEGDAVTPYYDPMIAKLIVHAPDRETALARLATALDHVAVEGVETN
                     RAFLTALARNHEFERMQVHTRWIDGRLDELTQAPALSRPDLWKATAAILFVTQSRSDTN
                     AIPWTNRDAFTGWRLGLGDDAIEAGQRVALTDSDEVSEELRIGPVKPGARYTVHSENGE
                     ALTLSARELTPGRWRVGEGDTVHLIDARLHAGVIELDTPEGRLVFRPAAPLAFAGGDAV
                     ADRAVTSPLTGMIVEIKVSDGQAVAEGDVVAVMESMKLEISIRAAAAGIASNISVSNGD
                     MVDRGQVIAEILPSEE"
     gene            15018..15977
                     /locus_tag="RIdsm_RS27245"
                     /old_locus_tag="RIdsm_05481"
     CDS             15018..15977
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271: 2-isopropylmalate synthase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009819988.1"
                     /locus_tag="RIdsm_RS27245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05481"
                     /product="hydroxymethylglutaryl-CoA lyase"
                     /protein_id="WP_057817106.1"
                     /sec_met_domain="HMGL-like (E-value: 4.8e-34, bitscore:
                     112.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDFPKFVEFREEGPREGFQIEKKIYPIEERIELIDMLSETGLKR
                     IQVGSFVSPKYVPQMADTGELFQRIKRKPGVNYTSLWLNDKGFRKALTAHEVDIDPRLL
                     FYPSEAFAKSNNNSTSAEMREKQRDWVRLYKEEGYTVDAAYVMTAFGCNLEGPIPQERI
                     LDDFRFILQLCEEEDIPVPILVVADTMGWGNPEAVKRMIGALRELAPEARIGMHIHDTR
                     GLGIANVYAALSMGVDMFESSVAGLGGCPFAGHGHARAAGNVCTEDAVFLCHELGIETG
                     IDLDKLIAAAVKAEEIIGVPLMGRVMHTGGLDKYRKSR"
     gene            15990..16904
                     /locus_tag="RIdsm_RS27250"
                     /old_locus_tag="RIdsm_05482"
     CDS             15990..16904
                     /NRPS_PKS="Domain: PKS_KR (8-178). E-value: 1.4e-23. Score:
                     75.7. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS27250_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009504375.1"
                     /locus_tag="RIdsm_RS27250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05482"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_057817108.1"
                     /sec_met_domain="adh_short (E-value: 1.3e-36, bitscore:
                     121.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKALDGKVVLVTGAGGGIGRDIALMAAAEGAAVVVNDLGASLKG
                     TGQTETAAQKVVEEIRAAGGNAIADGGNVTDPDAARAMVEAGVKEFGRIDAVVNNAGIL
                     RDGYFHKMTYEDFDAVVKVHLYGAFNTSRAAADYFREQEGGALVHMTSTSGLIGNLAQA
                     NYSAAKLGIAAFSKSVALDLKRWNVRSNCIAPFAWSRMISSIKTDTPEQVARVEKIKEM
                     TPAKVAPMACFLMSDRAADVSGQIFAVRKNEIFLFNQPRPVRSVHSGDGWTADEIAERA
                     IPALKSQFTPLEVSADVFSWDPV"
     CDS_motif       16014..16094
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RIdsm_RS27250_0001"
                     /evalue="6.50E-04"
                     /label="PKSI-KR_m1"
                     /locus_tag="RIdsm_RS27250"
                     /protein_end="35"
                     /protein_start="8"
                     /score="12.4"
                     /tool="antismash"
                     /translation="VVLVTGAGGGIGRDIALMAAAEGAAVV"
     aSDomain        16014..16523
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS27250_PKS_KR.1"
                     /evalue="1.40E-23"
                     /label="RIdsm_RS27250_PKS_KR.1"
                     /locus_tag="RIdsm_RS27250"
                     /protein_end="178"
                     /protein_start="8"
                     /score="75.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLVTGAGGGIGRDIALMAAAEGAAVVVNDLGASLKGTGQTETAA
                     QKVVEEIRAAGGNAIADGGNVTDPDAARAMVEAGVKEFGRIDAVVNNAGILRDGYFHKM
                     TYEDFDAVVKVHLYGAFNTSRAAADYFREQEGGALVHMTSTSGLIGNLAQANYSAAKLG
                     IAAFSKS"
     CDS_motif       16431..16493
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RIdsm_RS27250_0002"
                     /evalue="1.30E-05"
                     /label="PKSI-KR_m4"
                     /locus_tag="RIdsm_RS27250"
                     /protein_end="168"
                     /protein_start="147"
                     /score="17.7"
                     /tool="antismash"
                     /translation="VHMTSTSGLIGNLAQANYSAA"
     gene            16904..17698
                     /locus_tag="RIdsm_RS27255"
                     /old_locus_tag="RIdsm_05483"
     CDS             16904..17698
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009803518.1"
                     /locus_tag="RIdsm_RS27255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05483"
                     /product="citryl-CoA lyase"
                     /protein_id="WP_057817110.1"
                     /transl_table=11
                     /translation="MGKRKEKISSDIAWSTSDKISVRGLDLPNEILGHMNLGDLAFLQL
                     TGRKATPEESRVFNAIVITLVEHGITPSALAARMTYMGAPESLQAAVAAGLCGLGTVFV
                     GSMEGASKMLYEALPPEKLGTGVDLDALAVDTVEKFRARKMIVPGLGHPVHKPVDPRTP
                     RLFQIAAENDKFGEYIELIQKIQAVAEEKSGKMLPINATGAIGAICCEFGFPWKIVRGF
                     GVMARAIGLVGHILEESENPISYELWQRAEQEILETSGPGAK"
     gene            17702..18865
                     /locus_tag="RIdsm_RS27260"
                     /old_locus_tag="RIdsm_05484"
     CDS             17702..18865
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009504372.1"
                     /locus_tag="RIdsm_RS27260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05484"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_057817112.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 2.3e-26, bitscore:
                     87.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 2.7e-23, bitscore:
                     76.9, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 2.8e-34, bitscore:
                     113.3, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQTSAPDTHTDLRDALRALCAQFPPEYHRKFGEGETYPEEFVDAL
                     TREGWLAAMIPEEYGGSGLGLTEASIIMEEANRCGANAGHFHGQMYNMGTLLRHGSDAQ
                     KQKYLPGIASGELRLQSMAVTEPTTGTDTTKLKTTAVKKGDRYVINGQKVWISRIQHSD
                     LMILLARTTPLSEVKKKSQGLSIFMVDLKEAIGNGMEVRPIANMPGHETNEVFFDNLEI
                     PAENLIGTEGRGFYHILDGLNAERTLIAAECIGDGYWFVDKARAYAGDRVVFDRPIGQN
                     QGVQFPIARSYVNIEAANLMRFEACRRFDAGLDCGAQANMAKLLASEASWEAANACIQT
                     HGGFGFAREYDVERKFREARLYQVAPISTNLILSYVAEHILGMPRSF"
     gene            19009..19709
                     /locus_tag="RIdsm_RS27265"
                     /pseudo=""
     CDS             19009..19709
                     /NRPS_PKS="Domain: PKS_KR (27-101). E-value: 3.9e-07.
                     Score: 22.1. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS27265_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="RIdsm_RS27265"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGAEEARIFADEGAKVIVADVDDKGAKSVVQDIKDAGGTVMAVYL
                     DVSDAASWEKAIGEGQKAFGNINVLVNNAGIAFLKPVQDTSEEEWDKIFAINAKGVFSG
                     PGRFWKI"
     aSDomain        19090..19311
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS27265_PKS_KR.1"
                     /evalue="3.90E-07"
                     /label="RIdsm_RS27265_PKS_KR.1"
                     /locus_tag="RIdsm_RS27265"
                     /protein_end="101"
                     /protein_start="27"
                     /score="22.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="SVVQDIKDAGGTVMAVYLDVSDAASWEKAIGEGQKAFGNINVLVN
                     NAGIAFLKPVQDTSEEEWDKIFAINAKGV"
     gene            complement(19883..21085)
                     /locus_tag="RIdsm_RS27270"
                     /old_locus_tag="RIdsm_05487"
     CDS             complement(19883..21085)
                     /EC_number="2.8.3.-"
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1189: L-carnitine dehydratase/bile acid-inducible"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009504368.1"
                     /locus_tag="RIdsm_RS27270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05487"
                     /product="CoA transferase"
                     /protein_id="WP_057817114.1"
                     /transl_table=11
                     /translation="MDSQPQEPSPQKPAEGDGPLAGYRVLDLSVNVLGPVATQILGDMG
                     ADVIKIESPDGDYTRQVGPSRNPKMGALFLNANRNKRSVVLDLKKPDARVALLDLVRST
                     DVLVHSMRPGAAERLGVDYEAIRAVNPGIIHASASGFRLDSERRDWPAFDDVIQGASGV
                     AGLMARASGEPRYYPTVIADKLCGYILASSIAMAFVWRERTGHGQQVNVPMMDAMVNFN
                     LIEHLCGATLDRPDLGMGYSRVFSPHRRPYPTQDGHICVMAAMDNQWLRLFDAIGRPEL
                     RDDPRFATAALRTDHIDALYGILAEAIAGNTTAEWRRRFDAADVPKGPANSLEDLLVDP
                     YLVQTGYFERHEHPTEGALVTPRIPVQFSHSPGRVRRLPPRLGEHTEEVLSEIRPPRAD
                     T"
     misc_feature    complement(21292..21301)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: strong, score: 18.57"
                     /tool="antismash"
     gene            21436..22644
                     /locus_tag="RIdsm_RS27275"
                     /old_locus_tag="RIdsm_05488"
     CDS             21436..22644
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1282:
                     extracellular ligand-binding receptor"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF024850.4"
                     /locus_tag="RIdsm_RS27275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05488"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_057817116.1"
                     /transl_table=11
                     /translation="MNKFLQAVVGLGVAIAPLTSSPALAQAEEIVIPAIAAMSGPVAVT
                     GQDAQKGIAVALEHINADGGVAGRSLKIQLYDTQGNPGVVRQVMERLTRLERAPIILGC
                     EISAGTSAAAQFAEQARVPYLNSSAVSAELLERGYKWYFSDQITADSEASTVVSFLDHL
                     MTQGDVVPALLYEDSPRGAGTIERIEVLLEERGIEIAASAPYSRSDRNLLPPVKRVQTS
                     GANVVIWAGYTEDVVTGLQAMQQLDFKPYIIGIGGGPGDVRIPQLVDRDFIEDVNLSTV
                     DYFNPDMDRAQRFVKAYEEKHGIVPSSYASMCYRGAYTLKAALEETLEAGQDLTDENLR
                     AALLEIDIPGKELISPFSRIKFDEHGRNVGSQNLIAQWKEGGTKKVTVWPPEVAVEEPN
                     PLN"
     gene            22672..23547
                     /locus_tag="RIdsm_RS27280"
                     /old_locus_tag="RIdsm_05489"
     CDS             22672..23547
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0015803 - branched-chain amino acid
                     transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014684.4"
                     /locus_tag="RIdsm_RS27280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05489"
                     /product="branched-chain amino acid ABC transporter
                     permease"
                     /protein_id="WP_057817118.1"
                     /transl_table=11
                     /translation="MSVELLLQAAVSGFLMGGIYALIALALALVFGVMGVLNFAHGDLL
                     MVGMYGVVMVCASTGLSPFLAGVLLVPAMMAIGWAVFGRLIRPVVGSAPLVQAQLTIGL
                     SFVIQSAALLWFGADLFNVRTELGASTIHLGAIVVSVPLLIGFVIALVASGLLAWFLSA
                     TVWGYRVRATAEDPVMAQLCGVTVQRVQMWVFVGATGSLAVAAGCLMGFYHVTPVVGLQ
                     FSVLSLMIVVLGGLGDLRGAMVAALVLGVAEALAGAIFNSASAPAGLYILFGAVLLLRP
                     HGLLGRGATL"
     gene            23544..25412
                     /locus_tag="RIdsm_RS27285"
                     /old_locus_tag="RIdsm_05490"
     CDS             23544..25412
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF014684.4"
                     /locus_tag="RIdsm_RS27285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_05490"
                     /product="branched-chain amino acid ABC transporter
                     ATP-binding protein/permease"
                     /protein_id="WP_057817120.1"
                     /transl_table=11
                     /translation="MSGKPDTAAGLSRSPADAIAGALRSEGAVAILVIWVAVVIAFTVL
                     NAYWVSVAVMMLVWCYLCTAWNLIGGYVGQVSFGHGAFFGVGAYCTIYLATTYGISPWL
                     GMVVGMALSVVLALAAGYIPFRKGLSHLVFALLTLALAYALFYGVSGVRALGGTNGMFM
                     PLDETGLAALRFNDLWPFLLVIAVFNTVLLLVLQALLNSRHGFIWRATRDNEAAAAASG
                     INLFRSKQLAFAISAAATSVAGGFYAQFVGFIDPHSVLGVHVIILILLFSVVGGTGTLL
                     GPVVGTLVLFPLGEIMRVQLMSLGAGAHQLVYGAALVAVILLLPGGLIGQLRRALGGRW
                     FSGFTLAVPHSVAAGPLPRRHAADLEDGGKILTADGVGRDFGGVTALQSVDLEVRQGEI
                     LGLIGPNGAGKTTFFNLLGGSFPPSRGRITLLGQRVDGLAPHECTQLGIARTFQITQTF
                     ASFTVAEAVFTAALPGRSFDEARSIAGRVLVRVGLEARRDVPCAELTLSERRRLEIARA
                     LATGPSLLLLDEVMAGLTPTEVTSVITLIRGLRAEGITVVIIEHVMHAVMELCDRIVVL
                     DAGAVIAEGLPSEVSRDPHVIEAYLGKRAQQASAAAASDNADNGET"
ORIGIN
        1 tggcggcacc aaatgtgtcg ccggacgcgg agctcgtgaa ccggctcaag gatcgtgtcg
       61 gagagatcgt ctcgaaaccc ttccgcccgc gcgagatcca ctttgtcgaa gcgctgccca
      121 agacccgcag catgaaaacc atgcgccgtg tcgtgcgcgc cgcctttctc ggtgaagatc
      181 cgggcgatct gtcgtcgatc agcaacccgg aaaccattca gcccatcgca gacctgcaaa
      241 aggaaaagtc atgatcactg ttttcggagc cacgggcacg actggcgcgc ccctcgtcga
      301 tacgcttatg gcaaaaggcg cgaccgtgcg cgctgtcacc agcgacccct tcaagttaga
      361 cgcgctaaaa gccaaaggat gcgaggcggt cgcagcggat ttcacggacc ctgccgcgct
      421 ggcgcgggcc tgtgacgggg cggaaaagat atacctggtc acgcctgccc atctggacat
      481 gcgtcagtgg aaggcgaacg tgatcgaggc ggccaaggcc gcgggcgtgc gccatatcgt
      541 tgtggccacg gggcttggcg cgtcgcccaa ggcggggctg acctttggaa agtggcattc
      601 cgaaacccag gaactgctga agcaaagcag ccttgactgg acttttgtcc agccgaccta
      661 tttcatgcag aacctgctgt ggcaggccgg caacattgca aaggacgccg tgtactatga
      721 cgacgtgggc ggacccgtgg cctggatcga cgctcgcgac atcgcggatg tcgccgccga
      781 ggcgctgacc gctccggggt acgaaggcaa ggctcttggt ctgaccgggc ccgaagctct
      841 tgcaggggat gacatcgcgg cccttctgtc cggagtgacg ggacgaacag tgtcgtgcgt
      901 gtccctttcg gccgaggatg ccagggcggg catggtggcc ggcggaatgc aggacgaggt
      961 cgccggggcc atggtcgaac tggcctctat cgcgcccagg ggctacctag ccggcatcga
     1021 gaccacggtc agcgaggtgc tggagcgccc ggcgcgccga tttgccgatt tcgtcaccga
     1081 gaaccgggat gctttcgtca agtaacctga tggcggcgcc gctttatctc gaactggcgc
     1141 cgcctgagga agcggccact gagatcgatc atctgttcgt gtttcgcgat accggtgtgc
     1201 tgagcggtgg tggacgcggg cggttcgcaa ccgacctctt taccctttcg gtaacgcgcg
     1261 accacagcgg cggggcgcgt gtatcgctgg cgccaccgcg ctcgggtttc actctccgcc
     1321 caaggccatt ccatggtgtc gtggccgggc tgaggttgtc gtcacgaccg aagcacttac
     1381 ccgactccaa agggctggac atgctggccg cagaactggc ccgggttcag atcggggacg
     1441 gtgacctgcc cgcgctcatc gcagtgcttg acggcctcgc gagagacctg cgctttgccg
     1501 caccaaccgg agcttacagc gaccggacca aacgtcgaaa ggtgcgggcg gaaaccggcg
     1561 tgtcgcggcg gcggcttgcg accttgcgac gctttcgccg ggctctcggg cagcttgcgt
     1621 caaagaccct gccgctgagc gatctggcgc tggacgccgg atattacgat caatctcact
     1681 tgtccgccgc ttgccggatc ttcgccgaca aaccgcccgg cgcgttgcgc gctctgtcta
     1741 ttccgcgtcg ttttgacctt tcgctacaag atacgcgcct caaagaccgc ctaagattgg
     1801 tcattgacga atgaaatcga agaggaagac ccgccatgac gcaattcaaa ccgaaaaacc
     1861 ccgactatga cgcacgcgtg cgcgacagtt tcgatcgcca gaaggtgatg aacacgttgg
     1921 ggatcagcat tgccgagcta tcgcccggcc gcattgttct ggagatggca catgaggatg
     1981 ccctgaccca gcaacatggg tttttgcatg ccggaatcgt gtcgacagcg ctggacagcg
     2041 cctgcggata cgcggccttt tcgctgatgc ccgcagaagc ggccgttttg acagccgaat
     2101 tcaagatcaa cctgctcaac ccggcggacg gcgaacggtt tcgcttcgtc gctgacgtgg
     2161 tgaaaccagg caggacgctg accatatgcg aggcgcgtgc ctatgccgtg aagggccagg
     2221 atgaaaagct cgtcgcaacg atgaccggaa cgctcatggc gctggtcggg cgggccgggg
     2281 tcgcgggctg agcgtaaccc gaccgcggcg catccgggcg gtcgggtcga ttattcggcc
     2341 agctggatca gctgttcagc ggctcgcgac ctcggccaac cgtttcccgt aggcgcgcgc
     2401 ggtatccaga tcgccgccag tcgggtattc ctcgggggcg ctgtcagagg gggcaatcgc
     2461 cagaaggccg gaatacccgc ccgtccagtt cagcttttcc ggaccgtcgg ccttggtgtt
     2521 ggatggcatc aggcccacgc cgcaccaaag ctggccgtgc tgttgcgaca gggtgatgaa
     2581 atactggatg gtcgagaatt tatcgccatt gaccgtggcc gaggtggtaa acccaccagc
     2641 aatcttgtcc ttccagttct gcgtgaacca gggcttcgag ctggcgtcgg cgaatctctt
     2701 gaactgccat gcagggccgc ccatgtaggt cgggctgccg tagacgatgg catcggccgc
     2761 atcgagcgcg gcccaggccg catcgtcaag ctctccgtcg tctggtaatt tcaacagatt
     2821 gacctccgtg ccatcgacgc ccttggcacc ttcggcaacg gctttggcct gaacgtccgt
     2881 atggccatat ccactgtagt agacaatcgc gactttcgtc atggttcggt acaccttctg
     2941 attggaatcg gaataacacc gacttaggat gagcagttac aaaaagaaag ctgatcgttt
     3001 ttttggaacc ctcatttcgg tctggggcga aacctgctac ggagcgtgta ctttacgcgt
     3061 aaatatctga ataatattga taatccagtg attttgggcg acgggacgca gctgttgtga
     3121 tcgcagtcgc acaggctttt tgcgcgcgat tgctattggc tgcgcgcctt ttcatcagcg
     3181 atcctgatct cgagcatatg gtgctggatc ttgccgctgg tcgatctggg aaagtcctct
     3241 aacgcgatga agcgaatttc gcgcggtcgc ttatagccag ccaggctttc gcggcacaag
     3301 ttcagcagcg cctcggcatc cggcccgtca tcgtcaaagg caacaaaggc caccgggctt
     3361 tccccccatt tcgcgtcgaa ggccctgacc acggcggcat cgatcacatc gggatgcgaa
     3421 agaagcacac gttcgatttc cgccggatag acgttttcac ctccggtctt gatcaggtat
     3481 ttcgcccgat ccacaaagtc gaggctgccg tccgcattgc gccggaacag atcgcccatg
     3541 tggaaaaagc cgttgcgaaa atcgcgggcg ttggtgtcgt cggcgttcca gtacccggaa
     3601 aacaaagtcg ggccccgcac agccatttcg cccggcgttc catccgccac gtcgcggtcg
     3661 tcgggatcga ccagccgaac ctcgcaaaac gcgcttatgc gcttggaaag ccggtccggg
     3721 gtcacacccg gcgcaatcag atcggcggtt cccggcggca ggccggtttc agttgcgccg
     3781 aaggaattca gatagggcgt gtccagaagg gccgtcagtt cggcgatctg atgcggcggc
     3841 accagatcgg ccattgcgcc acaaaccttg atccccttca gcggcaaagg gttggcgcgt
     3901 cgttctgcga taaaggcgtc cagcgcaccg ggcatcatca cgaaccagcc gatccggtgg
     3961 cgcgacaacg cctcgttgat gaccgcaggc agcaaaccgt ctaccatcac cacggttccg
     4021 ccccgaagga ccgtcgccag cgcatgatca gtggacgcca tgtggaacat aggtgcccag
     4081 gcgatgaacc cgtcacaggg atccagtgcc agctgcgcgg caaaagccat ggagcgggcg
     4141 atatgcgcgc ggtggctgat gagcgcccct ttgggcagac ccgtagtccc cgaggtatac
     4201 aagatcgtca gaccagcctc tggatcgtcg accatggtcc cgatgcgcgg gtcttgctcg
     4261 gccccggcaa tggccgtttc caggtctggc ccgatggtca gacagggtgt cgacgcgacg
     4321 gcgtgataca tttctgaaaa gtccggttcg acgatcgcga gcaccggctc gaccagatcg
     4381 atgcagtgcc acagttcatc gggggcaagc cgccagttca ggcaagcgac aatcgcgcca
     4441 attcctgccg ctgccagttc gacctccagg tactccgagc ggttatgcga cagaatcgcg
     4501 atccggtcgc cgggcgccac gcccctggcc agaaacacgg cagccagacg atcgaccctc
     4561 cccagcaatt cggcatagct cagtctcttg ctgccgtcct cgatggccag atcccccgcg
     4621 caatcctgtg cgcgggttcg aaagatcgaa taaaggtcgg cgcgtcctgc acgcgaaact
     4681 tcggtcagca tggtctcccc ccttgcgcgg gcttcggttc agagaccctg cgccaggcgc
     4741 acgccctcat caatggcgcg cagcgcatcc agttcggcgg cctcctttgc cccgccgatc
     4801 atcgtaaccg ggacgctgcg tgcggtaagc tcttgggcca gggcccgttc cggttcctga
     4861 ccggtgcaca gcacaattgt atcggctgcg atgacctttg gcattccgtc cgcgacgatg
     4921 tgcagccccg cgtcgtcgat atgttcatag gtcaccccgc ccatggcctc gaccccatgt
     4981 ttgcgcagcg cgttgcgcag gatccaccct gtcgaaacac caagccctgc accgggttta
     5041 gcggtcttgc gctgcagcat gacgaccttg cggcgcgatg gcttcggtgc cagagggtcg
     5101 cccgccaggg cacccgagga gacaaattcg gggtccacac tccaggtttc gcaaaagacg
     5161 tcggaattgg cggtctcggc gggtttggtc actaggaact cggccacatc atgaccgatg
     5221 ccccccgccc ccatcaccac gacacggtcg cccgcctcgc ggtcaccgga cagaatttcg
     5281 gcgtaggtcg cgacgctggg atggtcgata cccggcaggt cgggaatgcg cggcgtgacc
     5341 ccggtggcga tgaccacatg gtcaaatccc tcaagatcgc tcgcctctgc ccgctgtccc
     5401 agacgctgcg tgaccccgtg tttctgcatc tgaccggcat aataccgcag ggtttcgtcg
     5461 aattcgtcct tgcctggtgc ggcgcgggcc agattcagct gaccgcccaa tttgtcctgc
     5521 gcttcgaaca gggtgacatc gtggcccagc cgcgccgcct cggcggctgt ggccatgccc
     5581 gcggcaccac cgccaacgac ggccactttc tttggggtgt cggttggcgt atcccggaat
     5641 tccgtttcac gcccggccct tggattgacc agacatccga ccggacgatc cgaaaagatg
     5701 aaatccagac aggcctggtt gcaggcgatg caagtgttga tctcgtccga gcggccctcg
     5761 cgcgtctttt tcacgaaatg cggatcagca agaaacggtc gcgccatcga gatcatgtcc
     5821 gcatcgccag aggcaagtat gtcttctgca agctggggtg tgttgatccg gtttgaggcg
     5881 accaccggga tcgacacggc cgctttcacg ttggctgccg ccttgcgcca ggcaccgcgg
     5941 ggcactgggt aggcgatcgt cggcacgcgg gcctcatgcc agccgatgcc ggtgttcagg
     6001 atatccgcac ccgcagcctc gatcttgcgg gccagtgcgg caatttcatc ggcgggcgcg
     6061 ccgccctcga ccagatcggc cgccgaaatc cggtagatga ccagaaagtc ggggccgcaa
     6121 cgttcgcgca ccgcgcgcac gatctcgacc gggaaccggt ggcggttcgc ggcgctgccg
     6181 ccccagtcgt cttggcgctt gttggtgtgg gttacggtga actcgttgat gaggtagccc
     6241 tcggacccca tgatctcgat gccatcgaag cctgcagcct gcgcattggc ggccgccacg
     6301 gcaaaatcct cgatggtacg gagaatgtcg gcttcggtca tttcacgcgg gatgaaccgg
     6361 ttgatcgggg cgcggatcgg cgacggggcc acacaccctt cgatctttgc atatcgcccg
     6421 gcgtggagga gttgcgcgca gatcaggctg ccttcggcct gcaccgcctc gcagatcggg
     6481 cgcaggccaa gcgcttcttc cggatcatcg attcgcggac cttctggatc gaatataccc
     6541 tcggcattgg gcgaaaaccc gccagtgacc agaagcgccg cctccccccg cgcccgctcg
     6601 gcgtaaaacg cgatctgttt ggctatgccg tcaggctcgg tttccaaccg cgtgtgcatc
     6661 gaccccatga tgacccgatt tcgcaatgta tgctggcctg cgcggatggg cgagagcatg
     6721 gtcccaaagc tctccgttgg cttattttcc actgtgggca tcctcctcaa aactacgctt
     6781 gatttgcatt ctaacatttg ttagattttt ggaaagataa ttttcgctta tggggaggag
     6841 caccgatgca attccagcca acagacgacc agaaggcgtt tcgcgacacc gcaaagcgct
     6901 tcgcaactga aaagcttgcg cccacatacc aagaacgcgc caacggccat acattcgacc
     6961 gtgcgctgat caaggagatg ggcgcactgg ggctgatcgg ggccgatctg cccgaggaat
     7021 tcgggggact cggcgaaagc tctgtcacgt cagggctgat cgtcgaagag atcgcctatg
     7081 ctgatttcaa cgcaagttac gtgcagcttc tgggctctct catgggaggc atggttgcca
     7141 aacatgcctc caaggacatc gcctcggaat gggtacccaa ggttgtttcc ggtgatgctg
     7201 tcattggtct gggcctgaca gagccgcgcg gcgggtcgga tgcggcgaac ctaattctga
     7261 aggccgagaa atccggcaac ggctggcggc tgaacggtga aaagacctcc atgagttttg
     7321 ccagccaggc ggatgcggcg gtcgtctttg cccgtactgg cgatcctgac ggcggctcac
     7381 gcggggtcag cgcctttttc gtcgatctga accaggaagg catcaagcgc acccattttg
     7441 acgacatcgg caccaagcct gtcgggcgcg ggtcggtgtt ctttgacgat gttttcgtgc
     7501 cagccgaaaa catgatggcg gaacaggacc gtgcctttgg cacgatcatg gcggggttcg
     7561 actattcccg cgccctgatc ggactggagt gtctgggggc cgcgcaggcg tcggtggatg
     7621 aaacctgggc ctacgttcag gaacgcgagg cattcggggc cccgatcgtg cagtatcagg
     7681 gtgtcagctt tcccttggcc gaggccgaga cccaactgac catgatgcgc cagctttgct
     7741 attacacgct ggacctgcgc gaccgtggcc tgccccacac ctctcaggcc gccatgtgca
     7801 aatggtacct gcccaaaacc gcctgcgaaa tccttcacca gtgcctgatc ctgcacggac
     7861 attacggcta caccaccgac ctgccccacc accagcgcta caacgatgtg ctcggcctgc
     7921 agatcggtga cggcaccgcg cagatccaga agctggtgat cgcccgcgaa aaggtcggtc
     7981 gcatggcgct gcagtatgac aagaaggcga agggagccgc gaaatgagcg accccatcct
     8041 cgtcacttcc gagggcaaca ccggcatcat cgaactggcc cgccccgaga aattcaattg
     8101 cctatcactt gaggtgcatg agcgtatttc tgtcgcgcgt gcggaattcg aggcgaaccc
     8161 cgctattcgg gcgatcctca tccgggcgca gggcaagcac ttttgcaccg gtgccgatct
     8221 ggtggaagtg aaaggtaaat tgaacgattc cgccgcgctg gaccatttca tcgcctttgg
     8281 catgaacaac ctgcgtgcgc tcgaaacctc ctccctccct gtcgtggtgg cagtgcaggg
     8341 gttgtgtctg gccggcggga tcgaactgat gctggcctgc gacgtgtgct ttgcggccga
     8401 aagcgcccag tttggcgatc agcatgcgca attcgggctg attcccggtt ggggtggctc
     8461 gcagcggttg acacggttga tggggcagcg cagggcgctc gacctgatgt tctcggcccg
     8521 ctggctcaag tcggacgagg ccaaagaggc cggattggtc aactacatcg tgccggatgc
     8581 ggacctgcac aagtctgcgc tggaatactg cgagaaaatc gccacccgtt cacgtcccgg
     8641 catcgccgag atgaagcggt tggcgcgtga aggcgcggac cttggtgtcg accagcagat
     8701 gcggcttgag cgcgatgccg cggtgcgtgc gctgcccagc gatgacgtgg ccgagggcct
     8761 cgacgcattc gagaaccggc gcgcccccag attcaaggcc tgaggacagc acatggactt
     8821 tactttgaac gacgaacaac gccagattta cgagtatggc ggccaactgg cgcagaagtt
     8881 cgacaacgat tactggctga gacacgcgcg caggcacgag tttccgcacg aaatgttccg
     8941 ccagatcgcc gatgacggtt tcctcggcat catggtgccc gaagaatacg gcggcgcggg
     9001 tcttggcatg accgaaatgg ccctgttcat ggagggcacc gccaatcacg gcattccgct
     9061 tttgatgatg gtggtcgggc cgaccatgtc gctggcccat atcgccagcc acgggagcga
     9121 gttccacaag aaagaactgc tgccggctgc ctgccgcggt gatatccaat tctgtttcgc
     9181 gatcaccgaa ccgggggccg ggtcgaacac gatgaaggcc actacgctgg ccaagcgtcg
     9241 gggcaaccgg ttcagcctgt cgggcgaaaa gaccttcatc accggggccg aagtggccga
     9301 ctactgcctc gtggtggcgc ggaccaaacc gcataccgag gtcagccgca agaccgacgg
     9361 ctttaccctg tttgccgtcg acctgaagaa aaagggggtc gacaagcagc gggtaaagat
     9421 ttcgatcccc ctgcccgagg aacagtggac cctgttcttt gacgaggtcg atctgggccc
     9481 cgaggatgtg gtcggcgaag ttgacgaagg attctcgatt ctgttcgaca gcctcaaccc
     9541 cgagcgtatc atcctggccg ccctgtgctg cggcatcggc cggttcgccc tgaacaaggg
     9601 cgtggcctat gcctccgagc gcaatgtgtt cggccaaccc atcggtgcgc accagggcgt
     9661 gcagcacccg atggccaagg cgcacacagc ggtcgagatg gccagcctga tgacccgtcg
     9721 cgcggcatgg gaattcgaca acaagctgcc tgccggtgcg tcgtcgaaca tggcgaaata
     9781 tgccgccgcc gaagccggga tcgaagcggt cgacgcggcg cttcaggcgc atggtggatc
     9841 gggctttacc gaagatacgg ggctttacga aatgtacccg ctggtccgcc tgctgcgcac
     9901 agcgccggtg aaccgcgaac tgtgcctgag ttttatcggc gaaaaggtca tgggcctgcc
     9961 acgatcctat tgatcgccac ggcttggaac ggagaacgac atgcaatttg gaatgcgctt
    10021 ccggcgggag gatgccgccg acaaggtaaa tgatcgcttc tggcacacga tcgagggcac
    10081 gccgctcgac gaggtgcgcc gtattcagga agagcggctg cgcgatcaga tggcgtatct
    10141 caaggcgaac tcgaccttct atcaggaaaa gttcgccgag gccggtgtgg acttcgacga
    10201 tatccgcacc atcgaagacc tgcaaaaact gccctatacc tacaagaccg agatccgcga
    10261 aagcctcgcc gccgagccgc cctttggcaa gcaccgtgcc gcgccgatgt cggaaataat
    10321 ccagatgcag gcctcgtcgg gcacgaccgg cagcccctca tatgtggccc tgacagaatc
    10381 cgacgccgag atgtggcacg agatgacagc gcgctgtttc tttgccaatg gcgtgcgtcc
    10441 cggcgatatg gtgctgcacg cattttcgct cgccaagggc tttgtcggcg gcatcccggt
    10501 gatgcaggga ttgcagtaca tgggcacgat cgatgtgccg gtgggcgccg atggcggtgc
    10561 ggaacggttg ttgcgcgcct gcgccgacac ccgcccgcgt tgcgtggtcg gcgctccgaa
    10621 ctttgtgctg cacctggctg aaaaggctcc cgaggtgctt ggctgcaagg ccagcgaact
    10681 gggtatcgag cgcgtgatcg tcggcggcga acccggcggc ggcattcccg caattcgggc
    10741 aaagatcgaa aaggcctggg gtgcgaaatg caccgagatg ctgggcggca ccgatctggg
    10801 cgtgacctat tgggccgagt gcgacgccca gtcggggatg cacatggtca acatggacta
    10861 tgtcattact gaattgctcg accccgaaag cggcgaaatc atcccttggg agaaaggtgc
    10921 cgaaggagag atgatctata ccgcacttgg ccgacaggcc agcccgctgg tcaggttccg
    10981 gtccggggac tatatcgagg tcatcgacac cgaatgctcc tgcgggcgga ccggacccaa
    11041 gatccgttgc accggccgca ccgacgacat gctgatcgtg cgcggggcga atgtcttccc
    11101 gtcggccatc aacagcatta ttaccgagat ggttccggac accaacggcg tcatgcgcat
    11161 cgtggccgat ttcgagggcc acaccacgca gggcgcgctg acggttattg tcgaacgcgg
    11221 ccccgatcgc gatccggccg atgacgtcgc cctcaaaaag aaaattgagc agcgactgcg
    11281 agactccctg gtcttcaagg ccgacgttca cctggttgcg gccgacactt tcgaaaaacc
    11341 tggcgccgct aaggtcgcct tcgttctcag gaaataccca gacctgccat gactaagatg
    11401 aaatcccttc tcgacaccgc gtcggacgac ttccgcgcca acgacgtgtc ttaccgcgaa
    11461 aaggtcgatg aactacatgc cctccggctc aaacagcgcg tcggcggccc cgaaatggcg
    11521 cgcaaacgtc atatggacaa aggcaagatc ctgccgcgcg aacggatcga acggctgatc
    11581 gacccgggca cgccctttct ggaactcggc gagctggccg ggttgaacaa atatgaaggc
    11641 gtgccaccgg gcgcgggcat catcacgggc atcggtgtga tcgaaggccg tcagtgcatg
    11701 atcatcgcca atgatgccac cgtaaagggc ggcacctatt tcggcatgac ttcccgcaag
    11761 catgtgcgcg cccagaagat cgcatggaag aaccgtctgc ccgtcatcac cctcgtggat
    11821 tccggcggtg ccttcctgcc ggatcaggaa aacatctttc ccgacgaagg ccaattcggg
    11881 tccatctttc accaacagat cggcatgtcg ggcgatggtg tgccgcaaat cgccgtggtc
    11941 atggggccct gcaccgcggg tggtgcatat attcccgcgc tctgtgacga agtggtgatc
    12001 gtgcgcggtc agggcttcat gtatctgggc ggaccggaat tgacctttgc cgcaaccggc
    12061 gaaaaggtcg aagccgaaga actgggcggc ggcaagatgc attcgtccgt ctccggtgtg
    12121 accgaccatt tggccgaaga tgacgcccac gctctggcca tcacgcgcga aattgtcagc
    12181 caccttggcg aaaaacccct accccgcaag acgcccgaaa cgccccgtgc gcccgcctat
    12241 ccggtcgaag agatttatgg actcgtcagc cgcgacccca aggtgccgac cgacaaccgt
    12301 gaaattcttg cgcggctgtt ggacgacagc gactttcatg aattcaagcc gctctatggt
    12361 gacaccatca tgaccggctg gggccgcatc catggccacg aggtcggtat tctcgccaat
    12421 accggcgtgc tcttcgttga ggccgcgttg aaggcgacgc atttcatcaa tctctgtgtc
    12481 cagcgcgata ttccgctgct gttcctggcc gatgtgaacg gcttcatggt gggccgcgag
    12541 gtcgaacaga tgggcatcgc caaggccggc gccaagatga tcacggccat gtcttcggcc
    12601 cgggtgccga aattcacaat catcaccggt ggctcttacg gggccggata cctggcgatg
    12661 ctgggccgcc cgttccagcc ggacgcaatg ttcgcctggc cgacgggacg gtcggcgatc
    12721 atggggccgg aacaggccgc cagcgtgctt gctcaggttc gcgcgcagat caacgaacgc
    12781 gaaggcaaaa gctggacccc cgaggaggag gaagcgttta aggcaccgat ccgcaaggaa
    12841 tacgaggatt ttcagggggc ttacaatttt gcgtccaatc tttggatcga cagcgtgatc
    12901 gagccttgtg agacccgtga cgtcatggcg ctgatgctgg atgtgacatc gcgcagaccc
    12961 aaggtcgata ccaacttcgg cgtgttcagg atgtgaggag cgaaccgtga aaatcaaaac
    13021 gcttctgatc gccaaccgcg gcgaaattgc ctgccggatc gcgcgcactg cgcgggccag
    13081 cggtatcacc cctgtcggcg tgcattcgca ggccgacgcc aatgccctgc atgtccgcaa
    13141 gattggcaaa tctgtctgta tcggcgccgg gcctgcatcc gagagctatc tgaaaatcga
    13201 cgcggtgatt gccgccgcgc aatcggtggg cgcggatgcg atccatcccg gttacggctt
    13261 tctggccgaa aaccccgatt ttgcccgtgc ggtcgaagcc gccggcatga tcttcatggg
    13321 gccgacgccg gaaacgcttg aacgtttcgg cgacaaggcc agcgccaaag aggccgccgt
    13381 ggcggccagc gtcccggtga tttcgggcgc cgaaggtgcg tggtccgatc ccgagcagat
    13441 tgccgaggag gtgcgccaaa tgggcctgcc ggtgctgctc aaggctgtcg gcggcggtgg
    13501 tgggcgcgga caacggctcg tctccgacga aaccacgctg gtcgaggaca tcgaaggcgc
    13561 gctgcgcgag gcgaaatcca ctttcggctc cgaagggctg ctgctggaac gtttcctgcc
    13621 cgaagcacgc catgtcgaag tgcagattgc aggcgacggc aaaggccatg tggtgcatct
    13681 gttcgaacgc gactgcacac ttcagcgccg ccaccagaag gtcatcgagg aggccccggc
    13741 ctggggcctg taccgttcac ttttgggcga catcgcgcat gacgcggtcc gcttgggcga
    13801 agcgctcgac tatcgcggtc tgggcacggt cgaatttctg gttgcggggg acgagtattt
    13861 cttccttgag gtgaatccac gcattcaggt ggaacatccc gtcaccgaag cgatcaccgg
    13921 gctggacctt gtcgcgcttc acctgcgcat tgccgaaggc gcgggccttg gactggtaca
    13981 ggatgacctc aagatcaatg gacacgcggt cgaggcgcgg ctttacgccg aagatccggc
    14041 gatgcaattc gccccgtcga cgggtacgct caccacgctc agcttgccat cgggcctgcg
    14101 tatcgacagc ggcgtcgagg aaggcgatgc cgtcacgccc tattacgacc cgatgatcgc
    14161 caagctgatc gtgcacgcgc ccgaccggga aaccgcattg gcacgtctgg ccacggcgct
    14221 tgatcatgtc gcggtcgaag gtgtcgaaac caatcgcgcc tttctgacgg cgctggcgcg
    14281 aaaccatgaa ttcgaacgga tgcaggtgca tacccgctgg atcgacggca ggctggatga
    14341 gctgacacag gcacccgccc tgagccgccc cgatctgtgg aaagcgaccg ctgccattct
    14401 cttcgtgacc cagtcgcgca gcgacacaaa cgccattccc tggaccaacc gtgatgcctt
    14461 taccggctgg cggcttggcc tgggcgacga tgcgattgaa gcggggcagc gcgtggcgct
    14521 caccgattct gacgaggtat ccgaggaact gcgcatcggc cctgtcaaac cgggtgccag
    14581 atacaccgtc cattcggaaa acggcgaggc gctgacactg tcggcacgtg aactgacccc
    14641 gggccgttgg cgtgtcggcg aaggcgacac cgtccatctg atcgacgcgc gcctgcacgc
    14701 gggcgtgatc gaactggaca cgcccgaagg ccgcctggtc tttcggcccg ccgcgcccct
    14761 tgcctttgcc ggcggcgatg ctgtggcgga tcgcgccgtg acctctccgc tgaccggcat
    14821 gattgtcgaa atcaaggttt ccgacggcca agctgtcgcc gaaggcgacg tggtcgcggt
    14881 catggaatcc atgaaactcg aaatctcgat ccgggcggcc gcggccggaa tagccagcaa
    14941 tatatccgtc tcgaatgggg acatggtcga tcgcggccag gtcatcgccg agattctgcc
    15001 atccgaggag tgatgaaatg agcgactttc ccaaattcgt cgagtttcgc gaagaaggcc
    15061 cgcgtgaggg ttttcagatc gaaaagaaga tttatccgat cgaagagcgg atcgaactga
    15121 tcgacatgct cagcgaaacc ggtctaaagc gcattcaggt cggcagtttc gtcagcccga
    15181 aatacgtgcc gcaaatggcc gacaccggcg agttgttcca gcgtatcaag cgcaaaccgg
    15241 gcgtgaacta cacatcgctg tggctgaacg acaaagggtt tcgcaaggcc ctgaccgcgc
    15301 atgaggtcga tatcgacccg cgtctgctgt tctatccttc cgaagcattc gcaaagtcga
    15361 acaacaatag tacctctgcg gaaatgcggg agaagcaacg cgactgggtc cgtctttaca
    15421 aggaagaggg atatacggtc gacgcggcct atgtgatgac cgccttcggc tgcaacctcg
    15481 aaggccccat cccgcaagag cgcatcctgg acgatttccg ctttatcctt cagctgtgcg
    15541 aagaagagga catccccgtg ccgatccttg tggtcgccga caccatgggc tggggaaacc
    15601 ccgaggcggt caaacggatg atcggcgccc tgcgcgaatt ggcgcccgag gcgcgcatcg
    15661 gtatgcacat ccatgacaca cgtgggctgg ggatcgccaa cgtttatgcg gccctgtcga
    15721 tgggcgtgga catgttcgaa agctccgtcg ccggtcttgg cggctgtcct ttcgcgggcc
    15781 acggccacgc gcgcgccgca ggaaatgtct gcaccgagga tgcagtgttc ctgtgtcacg
    15841 aactcggcat cgaaaccggc attgatctgg acaagctgat cgcagcggcg gtcaaagcag
    15901 aagagatcat cggtgtgccg ctcatgggcc gggtcatgca caccggcggg ttggacaaat
    15961 accgcaagtc acgctgaggg agcaagaaga tgacaaaagc acttgacgga aaggtcgttc
    16021 tggtcaccgg ggccggcggt gggatcgggc gtgatatcgc cttgatggca gccgcagaag
    16081 gcgccgccgt tgtggtcaac gatctgggcg cgtccctcaa aggcaccggt cagaccgaaa
    16141 ctgcggcgca gaaagtcgtc gaagagatca gggccgccgg gggcaacgcg atcgccgatg
    16201 gcggcaacgt caccgatccg gacgccgcgc gcgcgatggt cgaggccggg gtcaaggaat
    16261 tcggccgcat cgacgcggtg gtgaacaacg ccggcatcct gcgcgacggt tacttccaca
    16321 agatgaccta cgaggatttc gacgcggtgg tgaaggtcca tctctatggc gccttcaaca
    16381 ccagccgtgc ggcggccgat tatttccgcg aacaagaggg cggtgctctg gtgcacatga
    16441 cctcgacctc ggggctgatc ggcaatctgg cgcaggcgaa ttactcggcg gcaaagctgg
    16501 gcatcgcggc cttctcgaaa tcggtcgcgc tcgacctgaa acgctggaac gtgcggtcaa
    16561 actgcatcgc gcccttcgcc tggagccgga tgatctcgtc gatcaagaca gacaccccgg
    16621 aacaagtggc acgggtcgaa aagatcaagg agatgacacc ggccaaggtt gcaccgatgg
    16681 cctgcttcct gatgagcgac cgcgcggctg acgtgtcagg gcagatattt gcggttcgca
    16741 agaacgaaat cttcctgttc aatcagcccc gcccggtgcg gtcggttcat tccggtgatg
    16801 gctggaccgc cgatgaaatc gccgagcgcg ctattcccgc gctcaaatcg caattcacgc
    16861 cgctcgaagt ttcggcggac gtcttttcgt gggatccggt ctgatgggaa aacgcaaaga
    16921 aaaaatcagc tccgacattg cctggagcac ctctgacaag atcagcgtgc gcgggcttga
    16981 cctgcccaac gagatcctgg gccacatgaa ccttggcgat ctggcgttcc tgcaactgac
    17041 gggccgcaag gccacgcccg aggaaagccg ggtgttcaac gccatcgtca ttaccctggt
    17101 agaacatggg atcacgcctt cggctctggc ggcgcggatg acctacatgg gggcaccgga
    17161 atcgcttcag gcggctgtgg cggccggctt gtgcgggctt ggcaccgtct ttgtcggctc
    17221 gatggagggt gcctcgaaga tgctttacga ggcactgccg ccggaaaagc tgggcaccgg
    17281 tgtagatctg gatgcgctgg ccgtcgatac ggtggaaaaa ttccgcgccc gcaagatgat
    17341 cgtgccgggg ctcggacatc cggtgcacaa gccggtcgat ccgcgcaccc cgcgcctgtt
    17401 ccagatcgct gccgagaacg acaagttcgg tgaatacatc gagttgatcc agaaaattca
    17461 ggccgttgcc gaagaaaaat cgggtaagat gctgccgatt aacgccaccg gggcgatcgg
    17521 agcgatctgc tgtgaatttg gcttcccctg gaagatcgtg cggggctttg gcgtcatggc
    17581 acgcgccatc ggcctggtcg gtcatatcct cgaagagagc gaaaacccga tttcctatga
    17641 gctttggcag cgtgccgagc aggaaattct tgaaacgtcg ggtccgggag cgaagtaacc
    17701 gatgcagacg tcagccccag acactcacac cgatctgcgc gacgcgcttc gtgcgctttg
    17761 cgcgcagttt ccgccggaat atcatcgcaa attcggcgag ggtgaaactt atcccgaaga
    17821 gttcgtcgac gcgctgaccc gcgagggctg gctggcggcg atgatccccg aggaatacgg
    17881 cggctcgggc cttggcctga ccgaagcctc gatcatcatg gaggaggcaa accgttgcgg
    17941 cgccaatgcc ggtcacttcc acgggcagat gtacaacatg ggcacgcttc tgcggcacgg
    18001 ctcggacgcg caaaagcaga aatacctgcc cggcatcgcc agcggcgagt tgcgcctgca
    18061 atccatggcc gtgaccgaac cgaccaccgg gaccgacacc accaaactca agaccacggc
    18121 ggtgaaaaag ggcgaccgct atgtgatcaa cggccagaaa gtctggatca gccgcatcca
    18181 gcattctgac ctgatgatcc tgctggcacg caccacgccg ctgagcgagg tcaagaaaaa
    18241 gtcgcagggc ctgtcgatct tcatggtcga tctgaaagag gcgatcggca acgggatgga
    18301 ggtccgccca atcgccaaca tgcccggcca cgaaaccaat gaagtgtttt tcgacaacct
    18361 ggaaatcccc gccgagaacc tgatcggcac cgaggggcgc ggattttacc atattcttga
    18421 cgggttgaac gccgaacgga ccctgattgc ggcggaatgt atcggtgatg gatactggtt
    18481 cgtcgacaaa gcccgcgcct atgccggtga ccgcgtggtc tttgaccgtc ccattggcca
    18541 gaaccaaggc gtgcaattcc ctatcgccag gtcctatgtg aacatcgagg ccgccaacct
    18601 gatgcgcttt gaagcctgca ggcggttcga tgctgggctg gattgcggag cacaggcgaa
    18661 tatggctaag ctgctggctt cggaggccag ctgggaagcg gccaatgcct gcatccagac
    18721 ccacggtggc tttggtttcg cgcgcgaata cgatgtcgag cgcaagttcc gcgaggcccg
    18781 gctgtatcag gtggcaccga tctcgaccaa cctgatcctg tcctatgtcg ccgagcatat
    18841 ccttggtatg ccgcggtcgt tctgagatgt ttccgagcgg gacttgatct ctgttatgcg
    18901 ggacgcaagc cacatccttt taaactgccg tcacagcaaa cttaaaggat gaccgacatg
    18961 aaacgactcc agggaaagac tgcactgatc agtggtgcgg ccaatggcat gggggccgaa
    19021 gaggcacgta tttttgccga tgaaggtgct aaggtcatcg tggcggatgt cgatgacaag
    19081 ggcgcaaaat ccgtggtgca ggacatcaag gatgcggggg gcaccgtaat ggcggtgtat
    19141 ctggatgtgt ccgatgcagc cagttgggaa aaggcgatcg gtgaagggca aaaggcattc
    19201 ggcaacatca acgtgttggt caacaatgcc ggcatcgctt ttctgaagcc ggtccaggac
    19261 acgtcggaag aggaatggga caagatcttc gcgatcaatg caaagggggt tttctcggga
    19321 ccagggcggt tctggaaaat atgaaggccg cgggcgttgg gtcgatcgtc aatatatcgt
    19381 cgatctatgg tctggtcggc gcgccttcgg cagcggcatt tcaggcgacc aaaggtgcgg
    19441 tgcgactgct taccaaatcg acggcatcgg attacgcgcc gttcaacatc cgggtgaatt
    19501 cgatccatcc gggcgtgata cgcaccgcga tgacggaaga catgctggct gatccggacg
    19561 gtcagaagga gatacttggg gcaacgatta tggagcgccc ggccgagccg aaagaggtag
    19621 cttgggcggt gctgtttctg gcttccgacg agacatccta catgaccgga tccgaaatgg
    19681 ttgtcgatgg cggctatacc gcgcggtgaa acgcgtggag ccggaaggct ggaacagtcg
    19741 ggaccggttg gccgcgaacc gatcctggcc aactcggcat cggttgactt gggcgcgagt
    19801 ttccgacggg cgtcgtgaaa tccatgagcg aagggcacga ccggcatcga atacggctca
    19861 cttcatccct ggcctggttc cgtcaggtgt cggcgcgcgg agggcggatt tcggacagaa
    19921 cctcctccgt gtgctcgccc agccgcggtg gaagacggcg cacccggccg gggctgtgcg
    19981 agaactggac cggtatccgg ggcgtcacga gggcgccctc tgtcgggtgc tcgtggcgct
    20041 cgaaataccc ggtttgaacc aggtagggat caaccagcag atcctccagg ctgttggccg
    20101 gtcctttcgg cacgtcggcc gcgtcgaacc ggcggcgcca ctcggcagtt gtattccccg
    20161 cgattgcctc ggcgaggatc ccatataacg cgtcgatgtg atcggtgcgc aacgcggctg
    20221 tggcaaatcg tggatcgtcg cgcagctcgg gccggcctat ggcgtcgaag agacgcagcc
    20281 actggttgtc catcgccgcc atcacgcaga tgtgcccgtc ctgcgtcgga taaggccgac
    20341 gatgaggcga gaatacccgg ctgtaaccca tgcccagatc gggtcggtcg agggttgcgc
    20401 cgcagagatg ctcgatcagg ttgaagttga ccatcgcatc catcatcggc acgtttacct
    20461 gctgtccgtg gccggtgcgc tcgcgccaga cgaaggccat cgcaatggac gatgccagga
    20521 tatacccgca tagtttgtcc gcgattacag tggggtaata gcgcggctcg ccgctggccc
    20581 gggccataag cccggctacg ccgctggcac cctggatcac atcgtcgaaa gcaggccagt
    20641 cgcggcgctc gctgtccagc cggaaacccg aagccgaggc gtggataata ccgggattga
    20701 ccgcgcggat cgcctcgtaa tcaacgccga ggcgttcggc ggcaccgggg cgcatcgaat
    20761 gcaccagcac gtccgtcgaa cgcaccagat caaggagcgc gacccgcgcg tcgggttttt
    20821 tcaggtcgag cacgaccgag cgtttgttgc ggtttgcgtt gaggaacagt gcccccatct
    20881 tcgggttgcg cgacggtccc acctggcgtg tgtagtcgcc gtcgggtgac tcgatcttga
    20941 tgacgtcggc ccccatgtcg ccgaggatct gggtcgccac cggccctagc acgttgaccg
    21001 aaagatcaag caccctgtaa ccggcaagcg ggccgtcccc ctcggctggc ttctgcggtg
    21061 atggctcctg cggctggctg tccatttttc ttttcctttc gcggtatcgc acccttcgag
    21121 ccagcaatgc gcgccgcagt ccggcggtca gctggcccgc aacccaaggg cgcggcaccg
    21181 caaccttgcg gaagcatccc tgcaagaccc acactacttc gggagcggct cgcgaaagcg
    21241 gttccgcagg ccattagaac ggcgtcgcca tgagcgctca accgctgcag atcaaaaaac
    21301 acatctgtgc gcaaaaggcc cgcccggccc ggaggtcttg gcgcaggctg accgccccgc
    21361 ttaccctagg gcaccggagt cctgccatcg gtagatgccg ctttcggact tgcgggattt
    21421 tagggaggag ccaaaatgaa caagtttcta caggccgttg tcggcctggg cgtcgccatt
    21481 gcgccgctga cgtcttcacc tgcgctggcc caagccgaag aaatcgtgat accggcgatt
    21541 gccgcgatgt cgggaccggt cgccgtgacc ggacaggatg cgcaaaaggg gatcgcagtt
    21601 gcccttgagc acatcaacgc cgatggcggc gtcgccggtc ggtcgctgaa gatccagctt
    21661 tatgacacac agggcaatcc cggggtggtg cgccaagtga tggagcggtt gacccgcctc
    21721 gagcgggctc cgatcatcct tggctgcgag atcagcgcag gcacatcggc agcggcgcag
    21781 ttcgccgagc aggcgcgggt tccttacctg aactcgtcgg cggtgtcggc cgagctcctc
    21841 gagcgcggtt acaaatggta tttctccgac cagatcacag ccgattccga ggcgtccacg
    21901 gtcgtgtctt tcctggatca cctcatgaca caaggcgacg tcgtcccggc gctgctttat
    21961 gaagacagcc cgcgcggcgc cggaaccatc gagcggatcg aagttctgct ggaggagagg
    22021 ggcatcgaga tcgccgccag cgcgccgtat tcgcgcagcg atcgcaacct tctgccaccg
    22081 gtcaagcggg tgcagacgtc gggtgccaac gtggtgatct gggccggcta caccgaagat
    22141 gtggtgaccg ggcttcaggc aatgcagcag cttgacttca aaccctacat tatcggaatc
    22201 ggcggaggcc caggtgatgt gcgcatcccg caacttgtgg acagggactt cattgaggac
    22261 gtcaatctca gcacggtgga ctacttcaat cccgacatgg accgtgccca gcgatttgtg
    22321 aaggcttacg aggaaaagca cggcatcgtt ccgtccagct atgcgtcgat gtgctaccgc
    22381 ggagcataca cgttgaaggc tgcgctggag gagacgcttg aggcaggcca ggatctgaca
    22441 gacgagaacc ttcgcgccgc cctccttgag atcgacatcc ccggcaagga actgatctca
    22501 cctttctctc ggatcaagtt cgacgaacac ggccggaatg tcggatcgca gaatctgatc
    22561 gcgcaatgga aggaaggcgg cacgaaaaag gtcacggtct ggccgccaga ggtggctgtg
    22621 gaagagccca atcctctgaa ctgatgcgaa aactggacgg gagtggtcag gatgagcgtt
    22681 gagcttcttc ttcaggcggc agtttcgggg tttctgatgg gtggcatcta tgcgctcatc
    22741 gccctggccc tggcgctggt gttcggcgtc atgggcgtgc tgaacttcgc ccatggcgac
    22801 ctgctcatgg tcggcatgta cggcgtagtg atggtctgcg cctccacggg cctctcgccg
    22861 ttccttgcgg gcgtcctact agtgcctgcc atgatggcga tcggatgggc ggtcttcggg
    22921 cggctcatcc ggccggtcgt cggctccgcc cctctcgttc aggcgcagtt gaccatcgga
    22981 ctgtcattcg tgatccagag cgcggcgttg ctatggttcg gggccgacct gttcaacgtg
    23041 aggaccgaac tcggagcgtc gacaatccat cttggcgcca tcgtggtaag cgtgccgttg
    23101 ctgataggct tcgtcatcgc cctggtggcg tcggggctgc tggcctggtt tctctcggcg
    23161 accgtctggg ggtaccgcgt ccgtgccacg gcggaagatc cggtgatggc ccaactgtgc
    23221 ggcgtgacgg tgcagcgcgt gcagatgtgg gtcttcgtcg gcgcgacggg gtcgctggcg
    23281 gtcgccgccg gctgcctgat ggggttctat catgtcaccc cggtggtggg ccttcagttc
    23341 agcgttctgt ctctgatgat cgtggtgctg ggcggtctgg gtgatctgcg cggtgcgatg
    23401 gtggcggcgc tggttctcgg cgtggccgag gccctggccg gcgccatctt caacagcgca
    23461 tcggcgccgg cggggcttta catcttgttc ggcgccgtgc tgcttctgag gccgcacggc
    23521 cttctggggc ggggggcgac gttatgagcg gcaaacccga taccgcggcc ggcctcagtc
    23581 gatccccggc ggatgccata gcaggcgcgc tgcgcagcga aggtgcagtc gccatcctgg
    23641 tcatctgggt ggcggtggtg atcgccttca ccgttctgaa cgcctactgg gtcagcgtcg
    23701 cggtgatgat gctcgtgtgg tgctacctct gcacggcctg gaacctgatc ggcggctatg
    23761 tcggccaagt ctcctttggc cacggggctt tcttcggtgt cggtgcctac tgcaccatct
    23821 accttgcaac cacctatggg atcagtccct ggcttgggat ggtcgtcggc atggccctgt
    23881 cggtcgttct cgcgctggcg gcgggttaca ttccgttccg gaaaggtctc agccacctcg
    23941 tctttgcgct cctgacgctt gccctagcct atgcgctttt ctatggagtg tcaggggtca
    24001 gagcactcgg tggcaccaac ggcatgttca tgccgcttga cgagaccggt cttgcggccc
    24061 tgcgctttaa tgatctctgg ccctttctgc tcgtcatcgc ggtattcaac accgtgctcc
    24121 ttctcgtcct gcaggcgctt ctgaattcgc gccacggctt catctggcgc gccacccggg
    24181 acaacgaggc cgcagcggcg gcgtcaggca tcaacctctt caggtccaag cagctcgcct
    24241 tcgccatcag cgctgcggcg acctcggtgg cgggcggctt ctacgcgcag ttcgtgggct
    24301 tcatagaccc gcattcggtg ctgggggtac atgtaatcat tctgatcctg ctgttctcgg
    24361 ttgtcggtgg caccggaaca cttctggggc cggtcgtggg cacccttgtg ctcttccccc
    24421 tgggcgagat catgcgcgtg cagttgatgt cgcttggggc tggcgcgcac cagttggtct
    24481 acggggccgc ccttgtcgcg gtgattctgc ttctgccggg cgggctgatc gggcagttgc
    24541 gcagggcact gggcgggcga tggttttccg gcttcaccct tgccgtgccg cattccgtcg
    24601 ctgccgggcc gttgcctcgg cgccacgccg ccgaccttga ggatggcggg aaaattctca
    24661 ccgccgatgg cgtgggccgc gactttggcg gcgtgacggc actgcagtcg gtcgatctcg
    24721 aagtccgtca gggcgaaatc ctcggcctga tcggccccaa cggcgccggc aagacgacct
    24781 tcttcaacct gctcggcggt tcctttccgc caagccgcgg ccggataacc ctgctcgggc
    24841 agcgcgtcga cgggctggcc ccgcacgaat gcacccaact gggcatcgcg cgcaccttcc
    24901 agatcacgca gactttcgcg tccttcacgg tggccgaggc ggtgttcact gccgcgcttc
    24961 ccggccgctc cttcgacgaa gcccgcagca tcgcaggtcg ggtgcttgtc cgcgtcgggc
    25021 tcgaggcgcg ccgggatgtg ccctgtgcag agctcacgct gtccgagcgt cgtcggctgg
    25081 aaattgcgcg tgcccttgca acgggacctt ctctgttgct gctcgacgaa gtcatggcgg
    25141 ggcttacacc gaccgaggtg acaagcgtga tcacgctcat ccgtggcctg cgcgcggaag
    25201 gaatcaccgt ggtgatcatc gagcacgtga tgcatgcggt gatggagctt tgcgaccgga
    25261 ttgtggtgct cgatgcgggc gcggtgatag ccgaggggct gccaagcgag gtcagtcggg
    25321 atccccacgt gatcgaagcc tatctcggca agcgcgcgca gcaagcctct gccgccgcag
    25381 catccgacaa cgccgacaac ggagaaacct gaatgatgat gtttgatctg cccgaggacg
    25441 tcagggaagt gcagcagatg gtgcggcgcg tcgccaacga gcgcgtggcg ccccgcgccc
    25501 acgaaatcga ccgcagcggg gagtacccgc aggacatgtt cgatctgctg cgcgaactgg
    25561 ggatgttcac cttgccgttt ccggccgagc acggcgggat gggaagccag cttgccgcct
    25621 gcgtcgcggt cgaggaactg gcgcgcgtct gctataatac cgcctatctg ctgatcgtgc
    25681 agtgggtccc gttcggtgcg atcctgttcg gcggtgacga ggcccagaag gcgcgcttcc
    25741 tgcccggcct ggccgatggc agcctgcgga gtgcgctggc ggtcaccgag ccgcaaagcg
    25801 gatcggatgt tgccgggatc cgcacccgcg ctgtgcgcga gggcgacgct tatcgcatca
    25861 atggccagaa aatctggagc accaactcgg cggtcgccga ctttgttctg gtcgcggcca
    25921 agaccggcgc cagcgacagc accggagaga tcaacttctt catcgtcgaa aagggca
//
