LOCUS       NZ_CP031598            10855 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Roseovarius indicus strain DSM 26383 chromosome, complete genome.
ACCESSION   NZ_CP031598
VERSION     NZ_CP031598.1
KEYWORDS    RefSeq.
SOURCE      Roseovarius indicus
  ORGANISM  Roseovarius indicus
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Roseobacteraceae; Roseovarius.
REFERENCE   1  (bases 1 to 5445172)
  AUTHORS   Vollmers,J. and Petersen,J.
  TITLE     Genetic Globetrotter - A new plasmid hitch-hiking vast phylogenetic
            and geographic distances
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5445172)
  AUTHORS   Petersen,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2018) Single Cell Genomics, Leibniz Institute
            DSMZ, Inhoffenstr. 8, Brunswick 38126, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: DSMZ_RIdsm
            Expected Final Version            :: yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RS; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728195.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 05:52:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,061
            CDSs (total)                      :: 6,008
            Genes (coding)                    :: 5,925
            CDSs (with protein)               :: 5,925
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 24 of 83
            Pseudo Genes (incomplete)         :: 57 of 83
            Pseudo Genes (internal stop)      :: 17 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 3459815
            Orig. end                         :: 3470670
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031598.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..10855
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="14"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10855
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10855
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5855](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..5855
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    768..782
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     gene            complement(906..1664)
                     /locus_tag="RIdsm_RS16540"
                     /old_locus_tag="RIdsm_03333"
     CDS             complement(906..1664)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /NRPS_PKS="Domain: Abhydrolase_1 (51-146). E-value:
                     1.1e-12. Score: 40.1. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS16540_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1036: alpha/beta hydrolase fold protein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007818008.1"
                     /locus_tag="RIdsm_RS16540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03333"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_057818733.1"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.6e-09, bitscore:
                     37.0, seeds: 455, tool: rule-based-clusters)"
                     /sec_met_domain="PF00561 (E-value: 1.1e-09, bitscore: 36.5,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPDFLTTAQGRKIAYHRTEGTGPGVVFLGGFKSDMEGTKAVHL
                     EAWARRTGRAFLRFDYSGHGQSSEAFTDGAIGDWAADAMAAIGELTEGPQVLVGSSMGG
                     WISLLCARAMPEKVAGLVTVAAAPDFTEDSMWAGFDDSQRDALFEKGEVALPSEYGEPY
                     VITRRLIEEGRDNLVLRSPLSLPFPVRFLQGTADEDVEMSVALRLLEHAEGPDMRLTLV
                     DGADHRFSEPDCLALIEASVEEVISRAARG"
     aSDomain        complement(1227..1511)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS16540_Abhydrolase_1.1"
                     /evalue="1.10E-12"
                     /label="RIdsm_RS16540_Abhydrolase_1.1"
                     /locus_tag="RIdsm_RS16540"
                     /protein_end="146"
                     /protein_start="51"
                     /score="40.1"
                     /tool="antismash"
                     /translation="TGRAFLRFDYSGHGQSSEAFTDGAIGDWAADAMAAIGELTEGPQV
                     LVGSSMGGWISLLCARAMPEKVAGLVTVAAAPDFTEDSMWAGFDDSQRDA"
     CDS_motif       complement(1326..1391)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RIdsm_RS16540_0001"
                     /evalue="6.90E-05"
                     /label="NRPS-te1"
                     /locus_tag="RIdsm_RS16540"
                     /protein_end="113"
                     /protein_start="91"
                     /score="15.4"
                     /tool="antismash"
                     /translation="EGPQVLVGSSMGGWISLLCARA"
     gene            complement(1805..2023)
                     /locus_tag="RIdsm_RS16545"
                     /old_locus_tag="RIdsm_03334"
     CDS             complement(1805..2023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007818003.1"
                     /locus_tag="RIdsm_RS16545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03334"
                     /product="hypothetical protein"
                     /protein_id="WP_057818735.1"
                     /transl_table=11
                     /translation="MPGYNKQFELSVDDLELIEDALRRSKRELSAPNHDEIPSENEDAV
                     REIHDLLGRIHNQKIFYRPSNTTYISG"
     misc_feature    complement(2238..2251)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.0"
                     /tool="antismash"
     misc_feature    complement(2243..2259)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: medium, score: 22.58"
                     /tool="antismash"
     gene            2379..4358
                     /gene="thrS"
                     /locus_tag="RIdsm_RS16550"
                     /old_locus_tag="RIdsm_03335"
     CDS             2379..4358
                     /EC_number="6.1.1.3"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004829 - threonine-tRNA ligase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006435 - threonyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thrS"
                     /gene_functions="other (smcogs) SMCOG1162: threonyl-tRNA
                     synthetase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014880416.1"
                     /locus_tag="RIdsm_RS16550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03335"
                     /product="threonine--tRNA ligase"
                     /protein_id="WP_057818736.1"
                     /transl_table=11
                     /translation="MAQISLTFPDGNSRSYDQGVTPADVAASISNSLAKKAISAHVDGK
                     HWDLQWPIEADAAISINTMKDEAPANELVRHDLAHVMARAVQEIWPETKVTIGPVIENG
                     WYYDFDRAEPFTPEDLSQIEKRMKEIINLRDPVKTEVWERDRAIAHYEQTGEPYKIELI
                     EAIPGDEPLRMYWHGDWQDLCRGPHLQHTGQLPADAFRLMSIAGAYWRGDSSRQMLQRI
                     YGVAFTSKEKLKAYLNFLEEAEKRDHRRLGREMDLFHMQEEAPGQVFWHPNGWTIYTAL
                     QDYMRRKQRAGGYNEINTPQVVDRKLWEASGHWDKYQHHMFIVEVDESRDGENDDASAT
                     NKEQTRINALKPMNCPCHVQVFNQGLKSYRDLPLRLAEFGSCARFEPSGALHGIMRVRG
                     FTQDDAHIFCTEDQIQQECARFIDFLADIYRELGFPDFEIRFATRPEKRVGTDESWDYV
                     EGALENAIKAVGRDYVLEPGDGAFYGPKLDFYLTDAIGRVWQCGTFQVDPNLPERLGAT
                     YIAPNGEKTRPFMLHRATLGSFERFIGILIEEHAGKLPFWLAPRQVVVASIVSEADDYV
                     NEVVAKLRAAGVRAEADIRNEKINYKVREHSVGKVPVILACGMKEVDERTVSLRRLGEK
                     STSVEPLDDVTKALAKEATPPDLL"
     gene            4645..4935
                     /locus_tag="RIdsm_RS16555"
                     /old_locus_tag="RIdsm_03336"
     CDS             4645..4935
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875093.1"
                     /locus_tag="RIdsm_RS16555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03336"
                     /product="DUF2282 domain-containing protein"
                     /protein_id="WP_057818738.1"
                     /transl_table=11
                     /translation="MSNTTKTLAIAGAVTAALASYTTTATAAEQEKCYGVSLAGENDCA
                     AGAGTTCAGTSTVDYQGNAWTLVDAGTCETMDLPDDRMGSLEPLDRDLPES"
     gene            5001..5855
                     /locus_tag="RIdsm_RS16560"
                     /old_locus_tag="RIdsm_03337"
     CDS             5001..5855
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: DUF692"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020041954.1"
                     /locus_tag="RIdsm_RS16560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03337"
                     /product="DUF692 domain-containing protein"
                     /protein_id="WP_057818740.1"
                     /sec_met_domain="DUF692 (E-value: 1.1e-90, bitscore: 301.8,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDTTRFPTLPAGPGVGYKPQHFRDITTDAAPVTWLEIHAENYMG
                     DGGRPLAQLRHLAERFPISVHGVGLSIGGEGRLDPDHLARLRKLCDWLQPASFSEHLAW
                     STHDSHFLNDLLPLPYTAATLTRVARHIDEVQEALGRPMLLENPSSYLAFDESTYAEPD
                     FLNELARRTGCGLLLDVNNVFVSATNLNMDPRAYIDAFPLDRVGEIHLGGHDEDEDDHG
                     APLLIDSHGREVADPVWALLDHTLDRSGPRPLLIEWDTDVPDWPTLAAEARRAEAALAK
                     VPA"
     gene            5852..6607
                     /locus_tag="RIdsm_RS16565"
                     /old_locus_tag="RIdsm_03338"
     CDS             5852..6607
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014875095.1"
                     /locus_tag="RIdsm_RS16565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03338"
                     /product="DNA-binding domain-containing protein"
                     /protein_id="WP_057818742.1"
                     /transl_table=11
                     /translation="MTLSQTTFHDALLDSTQPVPDGLSDGQGRPAGRRFSVYRNNVAAG
                     LTDALETSFPAIAKLIGQENFRKVAGTFLRQHPPQNPMMMTYGADFPAFLETFQPLQPL
                     GYLPDVARLEQALRIAYHAADARPIDPAILQTLPPDALAGARFTLAPATQIIPSRWPIH
                     AIWAFNMEDGPKPQPGPQTVLITRPDYDPQMTPVTPGTAAFITALQSGETLSDATDTAT
                     TTDPGFALTPALSLLLETQAITDIRRGDT"
     gene            6608..7180
                     /locus_tag="RIdsm_RS16570"
                     /old_locus_tag="RIdsm_03339"
     CDS             6608..7180
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009814803.1"
                     /locus_tag="RIdsm_RS16570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03339"
                     /product="DoxX family protein"
                     /protein_id="WP_057818745.1"
                     /transl_table=11
                     /translation="MTALVSIHTALFTRIERADWLLPTLARFLFAAILLVYYWKSGLTK
                     LGDGLLGPFSPAVGAYAQIFPKATEAVTYDVTKLSLFHHLTVLAGTWAEFILPILIIAG
                     LLSRLASLGMIGFIAVQSLTDLYGHGGIEHEGTLGAWFDKAPDAIILDQRALWVFLLLV
                     IVVKGAGPLSLDRALSRAVAPEPTSRG"
     gene            complement(7325..7693)
                     /locus_tag="RIdsm_RS16575"
                     /old_locus_tag="RIdsm_03340"
     CDS             complement(7325..7693)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019295615.1"
                     /locus_tag="RIdsm_RS16575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03340"
                     /product="hypothetical protein"
                     /protein_id="WP_057818746.1"
                     /transl_table=11
                     /translation="MRNAALLLGVIGGVLALIVGFFIYGYTVFIDEYGEIDGLAYQVDR
                     VGLSRTVAFVAPLLAIAGGGMARIRALWGGALLLVSAGLMLYAFDFGVFTMFPIGMTAL
                     GGIFAIAAGKPDEPKSHF"
     gene            complement(7739..8053)
                     /locus_tag="RIdsm_RS16580"
                     /old_locus_tag="RIdsm_03341"
     CDS             complement(7739..8053)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008280687.1"
                     /locus_tag="RIdsm_RS16580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03341"
                     /product="ArsC/Spx/MgsR family protein"
                     /protein_id="WP_057818748.1"
                     /transl_table=11
                     /translation="MILYGLKTCDTCRKALKSLPDAEFRDVRADGVPGEVLESAHARFG
                     ASLLNTRSTTWRGLSEAERAGDPLSLLAAHPTLMKRPLIVDGGEMHLGWGRDVQAALLG
                     "
     gene            8266..8472
                     /locus_tag="RIdsm_RS16585"
                     /old_locus_tag="RIdsm_03342"
     CDS             8266..8472
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007817990.1"
                     /locus_tag="RIdsm_RS16585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03342"
                     /product="cold-shock protein"
                     /protein_id="WP_057818750.1"
                     /transl_table=11
                     /translation="MPTGTVKWFNTTKGYGFIAPDEGGKDVFVHISAVERSGLTGLADN
                     QKVGYELQDGRDGRQMAGELKLL"
     gene            complement(8503..8781)
                     /locus_tag="RIdsm_RS16590"
                     /old_locus_tag="RIdsm_03343"
     CDS             complement(8503..8781)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009503560.1"
                     /locus_tag="RIdsm_RS16590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03343"
                     /product="hypothetical protein"
                     /protein_id="WP_082647467.1"
                     /transl_table=11
                     /translation="MAFALVCSAGAAPASTPIADVICEPTHMMTKKLSRQFGEQLHSWG
                     TRGPEQVMQVWTDKRGDWTMVVAYATGTSCIVAMGENWEGNQAEDPA"
     gene            complement(8936..9205)
                     /locus_tag="RIdsm_RS16595"
                     /old_locus_tag="RIdsm_03344"
     CDS             complement(8936..9205)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008228500.1"
                     /locus_tag="RIdsm_RS16595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03344"
                     /product="hypothetical protein"
                     /protein_id="WP_057818755.1"
                     /transl_table=11
                     /translation="MRISLSLSAAALAALTALPAVAQEARLYPVPTNANYCPAGLQPIT
                     INGAICCGRPNTHVTWYEMKRHPVYRAATYTRSYNCPEGTKGCQ"
     misc_feature    9286..9295
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.44"
                     /tool="antismash"
     gene            complement(9583..10512)
                     /locus_tag="RIdsm_RS16600"
                     /old_locus_tag="RIdsm_03345"
     CDS             complement(9583..10512)
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1242: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011646949.1"
                     /locus_tag="RIdsm_RS16600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_03345"
                     /product="IS110 family transposase"
                     /protein_id="WP_151175234.1"
                     /transl_table=11
                     /translation="MPQDVIGVDIAKDWIDVFFLSTGRAERVPMATAELRAFAARARGA
                     LVVFEASGGYEHPLAEALGAADVTYARVNPRQAREFARATGRLAKTDRVDARVLAEMGR
                     ALALRPTPPADPGRARLAGLMGRRDDLGAMLRAEMARLRQARDASVRRDIGSMIALLRR
                     RIGKLEAEIAAVIGADEALSDRSRLLRTMPGVGPLLAASLLARLPELGRLDRRAIASLA
                     GLAPHACDSGRFRGKRRIWGGRAEVRRTLYLAGFIASRYDPALRAFRRKLQEAGKPVKL
                     AIVACARKLLTVLNAMLRDQREHRPAAG"
     misc_feature    complement(10486..10500)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.3"
                     /tool="antismash"
     misc_feature    complement(10496..10512)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 18.37"
                     /tool="antismash"
ORIGIN
        1 aatcacatgc gccatgccat ccacgccctc cccaagctcc ggcgcggccc gcgtcaccgg
       61 cccgccccac cgggcctgca cctccgccgt cacgctcgca tccacgatct ggtcctcgtc
      121 cgagtaatag aacagcgccg gcgtgctcac cccgccataa tccagccccg ccgcgtattt
      181 caccatcgcc gccatcggca gcaccgacac catcggatag cgcgtcgtcc agttcagcgc
      241 ctgcatctcg ttgcgcggcg agaacgagcg ggtctccccc gccaccaccg gcagccagta
      301 gcgcgccgcc ggcagcgtca gaagcggcgc gttggggttg ttgatgccga aattcggcga
      361 cacgaacgca atccccttca catcgcgcat cagcccggcc tcctgcgccg caatggccat
      421 ggccgtgccg cccgtcgagg tcgcgatcac caccacctcg cgacccacct tccggccaat
      481 cgccagcgcc tcggccacgt cgttgatcca gtcgcccgcc gtggcctccg ccatggcctc
      541 gccatcgcgc ccatgccccg taagccgggt gaacaccagg ttcgccccca gcgcctcggc
      601 cacgccatcg ggcaccggtc ggatctcctc ggaactggcg gaaaacccgt gcaggtaaac
      661 gatggccaac tcggtcggca cctcctccag cccgtaccag atgacccgct tctcgttgcc
      721 ggggcggata tcgtcgaacc gcgcctcctg ctcccgcaga tacgggtcga ccccgtcggc
      781 cagcacgcgc cggtcaaaac ggatctcggt gtccaccggc tcatatggcc cgaacaccca
      841 caggcccagg gcgaccaccg ccagaccggc cagcacccgc cccagccagc gcaccaccac
      901 ccgcatcatc cccgggcagc ccgcgaaatc acctcttcga ccgacgcctc gatcagcgcc
      961 aggcaatcgg gctccgaaaa ccggtgatcc gccccgtcga ccagcgtcag ccgcatatcc
     1021 ggcccctccg catgttccag caggcgcagc gcaacggaca tctccacatc ctcatccgcc
     1081 gtcccctgca ggaaccgcac ggggaacggc aggctcagcg gactgcgcag aaccagatta
     1141 tcgcgcccct cctcgatcag ccgccgggtg atcacgtaag gctcgccata ctcgctcggc
     1201 aacgccacct cgcccttttc gaaaagcgca tcacgctggc tgtcgtcgaa cccggcccac
     1261 atcgaatcct cggtgaaatc cggcgccgcg gcgaccgtca ccagccccgc caccttctcc
     1321 ggcatcgccc gtgcacagag cagcgaaatc cacccgccca tgctcgagcc caccagaacc
     1381 tgcggcccct cggtcaactc gccgatcgcc gccatcgcat ccgccgccca gtcgccgatg
     1441 gccccgtcgg taaacgcctc cgacgattgc ccgtgccccg agtaatcgaa ccgaaggaac
     1501 gcccggcccg tccgccgcgc ccacgcctcc aggtgcaccg ccttggtgcc ctccatgtcc
     1561 gatttgaacc cgccaaggaa caccacgccg gggcccgtgc cctccgtgcg gtgataggcg
     1621 atcttgcggc cctgggccgt ggtcagaaaa tctggtgcag tcatgtctcg tccttttcgg
     1681 cgcgcatcct gcaccggacg gcaccagcct tcaaaccgtt tcccgcccga tccgccgccg
     1741 gatccacgaa aaaagccgcg cccaatcgga cgcggcctga aggaacaacc ctgaaattcg
     1801 cggttcagcc gctgatatat gtcgtattgc tggggcggta gaagatcttc tggttgtgga
     1861 tacgtcccag aaggtcgtga atctcgcgca ccgcgtcctc gttctcagac ggaatctcgt
     1921 cgtggttcgg cgccgaaagc tcccgcttcg agcggcgcag cgcgtcctcg atcagttcga
     1981 ggtcgtccac cgacagttcg aattgcttgt tgtaacccgg cattcgcaac tcctgttgat
     2041 tcatggcgtg gattagcgag taagatagga aacacggcgc ccacgtaaag agaaatttct
     2101 caaatccacc aacaagttac ccatgtttcc tgcatgcgtt ggaataccgt gccccgcatg
     2161 cgttggcaca cttgcaggca gatcaatgac ttagctggcc atttcggccc gttcgctttt
     2221 gatatcccat gcgtcgcttt tgtgcataaa ttttcggcac ccccgctccg taccgccggc
     2281 tcttgacttg ggccccgccc cgcgccaaaa acccggcaca catatatacc cgcaaccggg
     2341 cgttccgtgg gcgccaaacc gacgaggagt tcaggctgat ggcccagatt tcccttacct
     2401 ttcccgatgg caattcgcgt tcctacgatc agggcgtgac cccggccgac gtggccgcat
     2461 cgatctccaa ttcgctggcg aaaaaggcca tctcggccca tgtcgacggc aagcactggg
     2521 atcttcagtg gccgatcgag gccgacgccg ccatctccat caacaccatg aaggacgagg
     2581 cccccgccaa cgagctggta cgccacgacc tcgcccacgt catggcccgc gccgtgcagg
     2641 agatctggcc cgagaccaag gtcaccatcg gcccggtcat cgagaacggc tggtactacg
     2701 atttcgaccg cgccgagccc ttcacgccgg aagacctctc gcagatcgag aagcggatga
     2761 aagagatcat caatctccgc gaccccgtga aaaccgaggt ctgggagcgt gaccgcgcca
     2821 tcgcgcatta cgaacagacc ggcgagccct acaagatcga gctgatcgag gcgatccccg
     2881 gcgacgagcc cctgcgcatg tactggcacg gcgactggca ggatctctgc cgcggccccc
     2941 acctccagca caccggccag cttcccgccg acgccttccg gctgatgtcc atcgccggcg
     3001 cctactggcg cggcgactcc agccgccaga tgctgcaacg catctacggc gtggccttca
     3061 ccagcaagga aaagctgaaa gcctatctca acttcctcga agaggccgag aagcgcgacc
     3121 accgccgcct gggccgcgag atggacctct tccacatgca ggaagaggcc cccggccagg
     3181 tcttctggca ccccaacggc tggacgatct acaccgccct gcaggactac atgcgccgca
     3241 aacagcgcgc cggcggctat aacgagatca acacgccgca ggtcgtcgac cgcaaactgt
     3301 gggaggcctc gggccactgg gacaagtacc agcaccacat gttcatcgtc gaggtcgacg
     3361 aaagccgcga cggcgagaac gatgacgcgt ccgcaaccaa caaggaacag acccgcatca
     3421 acgcgctgaa gcccatgaac tgcccctgcc acgtgcaggt gttcaaccag ggcctcaaat
     3481 cctaccgcga cctgcccctc cggctggccg agttcggctc ctgcgcgcgc ttcgaaccct
     3541 cgggcgcgct ccacggcatc atgcgcgtcc gcggcttcac ccaggacgac gcccacatct
     3601 tctgcaccga ggaccagatc cagcaggaat gcgcccgctt catcgacttc ctcgccgaca
     3661 tctaccgcga actcggcttc cccgatttcg agatccgctt cgccacgcgc cccgaaaagc
     3721 gcgtcggcac ggatgaaagc tgggattacg tcgaaggggc gctggaaaac gccatcaagg
     3781 ccgtcggccg cgattacgtg ctcgaaccgg gcgacggcgc cttctacggc cccaagctcg
     3841 acttctacct gaccgacgcg atcggccggg tctggcaatg cggcaccttc caggtcgacc
     3901 ccaacctgcc cgaacggctc ggcgccacct acatcgcccc caacggcgaa aagacccggc
     3961 ccttcatgct ccaccgcgcc acgctcggca gcttcgagcg cttcatcggc atcctgatcg
     4021 aggaacacgc cggcaagctg cccttctggc tggccccccg ccaggtcgtc gtcgcctcca
     4081 tcgtctccga ggccgatgac tacgtgaacg aggtcgtcgc caagctccgc gctgccggcg
     4141 tgcgggccga ggccgacatc cgcaacgaga agatcaacta caaggtccgc gaacattccg
     4201 tgggcaaggt tccggtcatc ctcgcctgcg gcatgaagga ggtggacgag cgcaccgtct
     4261 ccctccgccg cctcggcgag aaatcgacct ccgtcgaacc tctcgacgat gtaacaaagg
     4321 cgctggcgaa agaggcgacc ccgcccgacc ttctgtaaca tctgccaatt cgcgcggccg
     4381 gatattgaaa cattccgaaa caatccggcc gcgctgaaac aacttcccct tatatttcag
     4441 ccccttgcga aaagcgccca cctgacgggc gctgacacgc ccgtgtctga cgcgttcgtg
     4501 agtcgtcgtt tcggcgatgc tccctctatc tttctctcat cgcccgaccg gcgcgccacg
     4561 gccaccacgc cccacgaacg ggagcagagg ccgcaacgca ctgaaacggc gatagaaagt
     4621 tcaatctctc aagggagcta ccccatgtcc aacaccacca aaaccctcgc catcgccggc
     4681 gccgtcaccg cagcactggc ctcctacacc accaccgcca ccgccgccga gcaggaaaaa
     4741 tgctacggcg tgtcgctcgc cggtgaaaac gactgcgccg ccggcgccgg caccacctgc
     4801 gccggcacct ccaccgtcga ctaccagggc aacgcctgga ccctcgtcga tgccggcacc
     4861 tgcgaaacca tggacctgcc ggatgaccgc atgggcagcc tcgagccgct cgaccgcgac
     4921 ctgccggaat cctgacgcca accggtctgt gcgggatcac cccgcacagg ccacccccac
     4981 cccaaccaac aggtgccccc atgctggata ccacccgctt tcccaccctg cccgccggcc
     5041 ccggcgtcgg ctacaagccc cagcatttcc gcgacatcac caccgatgcc gcgcccgtca
     5101 cctggctgga aatccacgcc gagaactaca tgggcgacgg cggccgcccc ctcgcgcaac
     5161 tccgccacct ggccgaacgc ttccccatct ccgtccacgg cgtcggcctc tccatcggcg
     5221 gcgagggccg gctcgacccc gaccacctcg cccgcctgcg caaactctgc gactggctgc
     5281 aaccggccag cttctccgaa cacctcgcct ggtcgaccca tgacagccac ttcctgaacg
     5341 acctgctgcc cctgccctac accgccgcca ccctcacccg cgtcgcccgc cacatcgacg
     5401 aggtgcagga ggcattgggc cgccccatgc tgctcgaaaa cccctccagc tacctcgcct
     5461 tcgacgagag cacctatgcc gagcccgatt tcctgaacga actcgcccgc cgcaccggct
     5521 gcggcctgct gctcgacgtg aacaacgttt tcgtctccgc caccaacctg aacatggacc
     5581 cccgcgccta tatcgacgcc ttcccgctcg accgcgtcgg cgaaatccac ctcggtggcc
     5641 atgacgagga cgaagacgac cacggcgcgc cgctcctcat cgacagccac ggccgcgaag
     5701 tcgccgaccc ggtctgggcc ctcctcgacc acacgctcga ccgctccggc ccccgccccc
     5761 tcctcatcga atgggacacc gacgtacccg actggcccac gctggccgcc gaggcccgcc
     5821 gcgccgaggc cgccctcgcc aaggtgcccg catgaccctt tcgcaaacca ccttccacga
     5881 cgccctgctc gacagcaccc agcccgttcc tgacggcctt tccgacggcc agggccgccc
     5941 cgccggccgc cgcttctcgg tctaccgcaa caacgtcgcc gcgggcctca ccgacgcgct
     6001 ggaaaccagc ttccccgcca tcgccaagct gatcggtcag gagaacttcc gaaaggtggc
     6061 cggcaccttc ctccgccaac acccgccgca gaacccgatg atgatgacct acggcgccga
     6121 ctttcctgcc ttcctcgaaa ctttccagcc gctccagccc ctcggctacc tccccgacgt
     6181 cgcccgcctc gaacaggccc tccgcatcgc ctaccacgcc gccgacgcgc gccccatcga
     6241 ccccgccatc ctgcaaaccc tgccgcccga cgcgctggcc ggggcccgct tcaccctcgc
     6301 ccccgccacg cagatcatcc cctcccgctg gcccatccac gccatctggg ccttcaacat
     6361 ggaagacggc cccaagccgc aacccggccc ccagaccgtg ctcatcaccc gccccgacta
     6421 cgacccgcag atgacccccg tcacccccgg caccgccgcc ttcatcaccg ccctgcaatc
     6481 cggcgaaacc ctctccgacg ccaccgacac agccaccacg accgaccccg gtttcgccct
     6541 cacccctgcg ctctcgctcc tcctcgaaac gcaggcgatc accgacatca ggaggggaga
     6601 cacctagatg accgccctcg tttccatcca caccgcgctg ttcacccgga tcgagcgcgc
     6661 cgactggctc ttgccaaccc tcgcccgctt cctcttcgcc gcgatcctgc tggtctatta
     6721 ctggaagtcc gggctcacca agctgggcga cggcctcctc ggccccttca gccccgccgt
     6781 cggcgcctat gcccagatct tcccaaaggc gaccgaggcc gtcacctacg acgtgaccaa
     6841 gctctcgctc ttccaccacc tcaccgtgct ggccggcaca tgggccgaat tcatcctgcc
     6901 catcctcatc atcgcgggcc ttctgtcgcg cctggcctcc ctcggcatga tcggcttcat
     6961 cgccgtccaa tccctcaccg acctctacgg ccacggcggc atcgagcacg agggcaccct
     7021 cggcgcatgg ttcgacaagg cgcccgacgc cattatcctc gatcagcgcg cgctctgggt
     7081 cttcctgctc ctggtgatcg tcgtgaaggg cgcagggccc ctgtcgctcg accgggcgct
     7141 gtcgcgcgcc gttgcgcccg aaccaacatc tcgtggctga acccaccgaa cgccacttta
     7201 accaaccgcc ctgccgacac ccgcaccgac gcaataccga caaaataccg acgttatacc
     7261 gacgtggcaa acccagtaaa aacagggccg ttaacctgat tcgcccaaaa cccgctctgc
     7321 cgcttcagaa atgcgacttc ggttcgtccg gtttccccgc cgcgatggca aagatacccc
     7381 ccagcgcggt catcccgatc gggaacatgg tgaacacccc gaaatcgaac gcgtaaagca
     7441 tcagcccggc cgaaacgagc agcagcgccc cgccccacaa ggcccggatg cgcgccatcc
     7501 ccccgcccgc aatcgccagg agcggcgcca cgaaggccac ggtccggctc agcccgaccc
     7561 ggtcgacctg gtaggccagc ccgtcaatct cgccatactc gtcgatgaag acggtatagc
     7621 catagatgaa aaaccccacg atcagggcca gaaccccgcc gatcacgcca agaagcagcg
     7681 ccgcatttcg catgtatgtc ctccggttgc ttcacagcca gataggcatt cccgccggtt
     7741 atccaagaag cgccgcctgc acgtcacgcc cccagcccag gtgcatctcg ccgccgtcca
     7801 cgatcagcgg ccgcttcatc agcgtcggat gcgcggccag caggctcagc gggtcgccgg
     7861 cgcgctcggc ctcgctcaaa ccccgccacg tggtcgagcg cgtgttgagc aaagacgcgc
     7921 cgaaccgcgc atgcgccgat tccagcacct ccccgggcac gccatccgcc cgaacgtcgc
     7981 gaaactcggc atccggcagg gatttcaacg ccttgcggca ggtatcgcag gtcttcaagc
     8041 catatagtat catgtcgcct cgcccaattt ttcacctgat agcgtgaccc ggcccaaaga
     8101 tcacgtgggt tttgcttgct ttttacattg ccggtgcaat catcaaagca gtgacgctga
     8161 cctatcagcc gccgacttcg aatttccgtg gccggacctg ctaagtctgc tcatgccaag
     8221 gcccggcgca taccgggaaa gtgaagacac ggaaggagat acggcatgcc gaccggcacc
     8281 gtaaaatggt tcaacaccac caagggctac gggttcattg cacccgacga aggcggaaag
     8341 gatgtatttg tgcacatctc ggccgtcgaa cgctcgggcc tgaccggcct cgccgacaac
     8401 cagaaggttg gctacgagtt gcaggacggg cgcgacgggc gccagatggc gggcgagctc
     8461 aagctgctct gacacagcca ggccagtcta tttcagtcta aatcaggccg ggtcctcggc
     8521 ctggttcccc tcccagtttt cccccatcgc gacgatacag gatgtccccg tcgcgtaggc
     8581 aaccaccatt gtccagtcgc cgcgcttgtc ggtccagacc tgcatcacct gttccgggcc
     8641 gcgggtgccc cagctgtgca gctgctcgcc gaactggcgc gacagcttct tcgtcatcat
     8701 gtgcgtgggc tcgcagatca cgtcggcaat cggcgtgctg gccggcgcgg ccccggcgct
     8761 gcacaccagg gcaaaagcca tgaaaactcg cattggtcct gcgtcctttc gttcactgct
     8821 ctttcgggca atgtaacaga atcatgacgc acctgtatat accttgaata tacaaaaggc
     8881 gcgaagccca ccgctccgcg cctttcgccc accctgttcg aaggggaagt cgtgcttact
     8941 ggcagccctt ggtgccctcg gggcaattgt acgagcgcgt ataggtcgcc gcccggtaaa
     9001 ccgggtgccg cttcatctcg taccaggtca cgtgggtatt cggacgcccg cagcagatcg
     9061 cgccgttgat ggtgatcggc tgaagcccgg ccgggcagta gttcgcgttg gtcggcaccg
     9121 ggtacagccg ggcctcctgg gcgacggccg gcaaggcggt cagcgcggcc agcgcggcgg
     9181 ctgagagaga gagggaaatg cgcatatgga cctcgtttac ggttactgaa aaggctttgg
     9241 aggaacctct gcgtggaatg gtaccgcttc ggcgggggct gtcaaagttt tttgagggga
     9301 aacagtgcgt ttcagggtgg tggcggggcg attatcgaga caactgccat gtccaaccgg
     9361 caccgacccg cttgagaacg agcaccgccg ggcgagcgcc ggcccgtggg gaggcgctgc
     9421 aacgatcctg gctgccgctt tatggtaccg aatacatcct cgaccgaagc gtcgcgctac
     9481 acctcaaaag cgcctgcccg ccgggacggg ccggcgctcg cccggcgccg cgccaaggcg
     9541 cggctctgtt ccgggcgtgt gctcccgtag caactgtctt tcttatcctg ccgctggccg
     9601 gtgctctctt tgatcccgca gcattgcgtt gaggacggtg agcagcttgc gggcgcaggc
     9661 gacgatggcg agtttgaccg gttttcccgc ctcctgcagc ttgcgccgga aggcccttag
     9721 cgccgggtca taccggctgg cgatgaaccc cgcgaggtag agcgtgcgcc gcacctccgc
     9781 gcggccgccc cagatccgcc gcttcccccg gaaccggccg ctgtcgcagg catgcggcgc
     9841 cagaccggcg aggctggcga tcgcccggcg gtcgagacgg cccagctcgg gcagccgggc
     9901 cagcaggctt gccgccagca gcggccccac ccccggcatc gtccgcaaga ggcgcgaccg
     9961 gtccgacagc gcctcatccg ccccgatcac cgcggcgatc tcggcctcga gcttgccgat
    10021 ccggcggcgc agcagcgcga tcatgctgcc gatatcgcgg cggacagagg catcgcgggc
    10081 ctgacgcagg cgcgccatct cggcccgcag catcgcgccg agatcgtccc ggcggcccat
    10141 caggccggcc agccgcgccc gcccgggatc ggccggcggc gtcgggcgca aagccagcgc
    10201 ccgacccatc tccgccagca cccgggcatc gacccggtcg gtcttggcca gccggcccgt
    10261 ggcgcgggcg aactcccgcg cctgccgcgg gttgacccgg gcgtaggtga catccgccgc
    10321 gccgagcgcc tcggccagcg ggtgctcgta cccgcccgag gcctcgaaca ccaccagcgc
    10381 cccccgggcc cgggcggcga aagcccgaag ctcggcggtc gccatcggca cccgctccgc
    10441 ccgaccggtg gaaagaaaga agacgtcgat ccagtccttg gcgatatcga cgccgatgac
    10501 atcttgtggc aaagtcatgg ggcctgtcct tgatctgcgg gatcggctgg ttgcacagcc
    10561 ctccctggca actgttcagg tttgacaacg gtcggcagac gagccccggg ctacgcgacg
    10621 gtctcaagga ccaagggtgg gacggggtct cgcctgccga tacacaatat cgcacagatc
    10681 aaagagacaa gggtgggtaa aacccacctc tccctcatcc caatcaacgt caccgtcggt
    10741 gggttcgcac ccaccctacc cctgccatcg caacgccctg caaccttaac ggatcgttca
    10801 aagatttatt ctactcctaa accaacaccg cccatcaacg agcccggcca ttcca
//
