LOCUS       NZ_CP031598            22225 bp    DNA     circular CON 28-MAR-2024
DEFINITION  Roseovarius indicus strain DSM 26383 chromosome, complete genome.
ACCESSION   NZ_CP031598
VERSION     NZ_CP031598.1
KEYWORDS    RefSeq.
SOURCE      Roseovarius indicus
  ORGANISM  Roseovarius indicus
            Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
            Roseobacteraceae; Roseovarius.
REFERENCE   1  (bases 1 to 5445172)
  AUTHORS   Vollmers,J. and Petersen,J.
  TITLE     Genetic Globetrotter - A new plasmid hitch-hiking vast phylogenetic
            and geographic distances
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5445172)
  AUTHORS   Petersen,J.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2018) Single Cell Genomics, Leibniz Institute
            DSMZ, Inhoffenstr. 8, Brunswick 38126, Germany
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: FEB-2018
            Assembly Method                   :: HGAP v. 3
            Assembly Name                     :: DSMZ_RIdsm
            Expected Final Version            :: yes
            Genome Coverage                   :: 100.0x
            Sequencing Technology             :: PacBio RS; Illumina
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728195.1-RS_2024_03_28
            Annotation Date                   :: 03/28/2024 05:52:02
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,061
            CDSs (total)                      :: 6,008
            Genes (coding)                    :: 5,925
            CDSs (with protein)               :: 5,925
            Genes (RNA)                       :: 53
            rRNAs                             :: 1, 1, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 1, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 47
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 83
            CDSs (without protein)            :: 83
            Pseudo Genes (ambiguous residues) :: 0 of 83
            Pseudo Genes (frameshifted)       :: 24 of 83
            Pseudo Genes (incomplete)         :: 57 of 83
            Pseudo Genes (internal stop)      :: 17 of 83
            Pseudo Genes (multiple problems)  :: 15 of 83
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:57:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1362043
            Orig. end                         :: 1384268
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP031598.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22225
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="6"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..22225
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22225
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12225](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12225
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    complement(12..26)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    complement(190..206)
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 23.01"
                     /tool="antismash"
     misc_feature    567..578
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.07"
                     /tool="antismash"
     misc_feature    764..777
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            974..2461
                     /locus_tag="RIdsm_RS06320"
                     /old_locus_tag="RIdsm_01272"
     CDS             974..2461
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007119829.1"
                     /locus_tag="RIdsm_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01272"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_057814589.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 3.9e-29, bitscore:
                     100.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAQEQGTTLMTARWVVGHEDGRHVLFENGEVAFENGRITFVGHG
                     FPGEAARRIDCGDAVLGPGFIDLDALSDLDTTVLGFDNQPAWKKGRVWPASYMRAGPRE
                     MYTPEDLAWQKRYAFTRLIRNGITTALPIASLFYREWGETPEEFAAAADAAEELGLRVY
                     LGPAYRTGNTFVTDDGEIDFHFDEARGLDGLKAAEAFCRDHEGRAGGLIRTMLAPDRIE
                     TCTEELLRRTAAASADLGVPVRLHCCQSVFEYESVLRMHGKSPPEWLLSLGFLSERSIL
                     PHLTVISGRNGITHDGPDLQILADSGASLAHCPLVMARGGLALDDFATYREAGLTIGMG
                     TDTHPPDMILNMQAGLLMGRLSAGRPQAVRSEDMYDAATLGGAKALGRSDLGRLEPGAC
                     ADITVIGLDDPAMGQVIDPIQTLMLNGSGRDVRTVVIDGRVVMRDGVIPGVDEAAMQVQ
                     AQAQFDGLVRQYPDRTHGHPPLSDIFSSSYPLRRAAS"
     gene            2458..3912
                     /locus_tag="RIdsm_RS06325"
                     /old_locus_tag="RIdsm_01273"
     CDS             2458..3912
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007119819.1"
                     /locus_tag="RIdsm_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01273"
                     /product="amidohydrolase family protein"
                     /protein_id="WP_057814592.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.4e-34, bitscore:
                     116.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLLIRNVTAVTVDAGRRVIENAAIAVRGDRIVYVGSDADLPAE
                     FEAARKVIDGHGMAAMPGLIDSHSHAGHGLVRSLGAGNTEVWFQACEEIYARGSTVDFW
                     RAEAELAQLERLMAGVTTNLTLLGGGADIYRTDDPVYGDAHCAATTASGLRTVLAVGPG
                     RPPFPKPYKALQNGEAQDVRLSFARQMEVSEDLIRRHDGVLDKRTGIALIMPVYHAHHM
                     EDAADAKAIREMSEVVADMRARHGVLYTQDGHRDGTIALAQGLGTLGPFALLSHSVDLT
                     DADFAALRKTGASIVHNPTAIMSIYGRCPAPELIDAGVRVVLGSDAGAPDRGFDMFRHM
                     KQAMLYHRRHFADPAYMPPGKVLEMATIDAADALGLGDELGSIETGKKADIILIDMKKP
                     HLSPVNMPLTRITHFATAADVDTVLVDGRVVMEGRQVRTLEPGAVMEAAGVELAKALER
                     TGLTALTEEPAGMWGATRFAGGEAGS"
     gene            3909..4610
                     /locus_tag="RIdsm_RS06330"
                     /old_locus_tag="RIdsm_01274"
     CDS             3909..4610
                     /GO_function="GO:0036361 - racemase activity, acting on
                     amino acids and derivatives [Evidence IEA]"
                     /GO_process="GO:0006807 - nitrogen compound metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008279263.1"
                     /locus_tag="RIdsm_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01274"
                     /product="aspartate/glutamate racemase family protein"
                     /protein_id="WP_057814594.1"
                     /transl_table=11
                     /translation="MKIHVVNPNSTAAMTRTIAETARAVARAGTTITASNPAHGPASIQ
                     GYYDVAACMPGLLEEAGRHRDADAVIVACFDDTGVDALRAMLDVPVIGIGEAAYHAASL
                     ISTRFSVVTTLPRSVPGLEANLVRYGLMARCGSVRASRVPVLDLEKPGGEAERLIAAEV
                     RLAVEEDMAECIVLGCAGMAEMRARLAEAFGIPVIDGIGCAVGFVETLVAAGLSTSKAG
                     GYASPFVAEMA"
     gene            complement(4787..6202)
                     /locus_tag="RIdsm_RS06335"
                     /old_locus_tag="RIdsm_01275"
     CDS             complement(4787..6202)
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009178478.1"
                     /locus_tag="RIdsm_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01275"
                     /product="S8/S53 family peptidase"
                     /protein_id="WP_057814596.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 8.6e-06, bitscore:
                     23.5, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKPETHPDYDALWHLVALGILTPDHAPNGWQVAPDAPRPTRVAV
                     IDTSVAADHPNLRPAINRDLALDLFSTRLGAFPYRDGTARIGALDLNAGTPVVDGLPRA
                     SELLAEMVDRLSHDGTAWLDGIQPMTGADFSSHGTAICGLVGARPAIARAADGYPSPVP
                     GHDNVPLPYAGVDPHCEIVPISTNYNPDPEQLILALLYAELIDADVVLIPRTISDPSRT
                     VPELNRMISDHALRDLVAPTAITPAELEMWEELATLLVQVSHQRPIVCAAGNSNEEHGI
                     YPANLASEHNGIISVGAINAKGVGSSYSDTRHVTLCGPSDDGETYDRGEIRLDPHRADQ
                     TLPAHASAASNEKFSAFDIISTDVPGIYGYAGGPFLGDEPEIGLREFGSYFCRFGGTSA
                     ASAIVAGVLSLARSTGRLSPDADGIEAKSFLLTLGVKVSRAGQEITVPAWNGELSFPDS
                     PAPAETPPATAPA"
     gene            complement(6207..7133)
                     /locus_tag="RIdsm_RS06340"
                     /old_locus_tag="RIdsm_01276"
     CDS             complement(6207..7133)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009178626.1"
                     /locus_tag="RIdsm_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01276"
                     /product="phosphatase PAP2 family protein"
                     /protein_id="WP_236553197.1"
                     /transl_table=11
                     /translation="MFVDYDQELNTAGLLQRHRLVVTAAGLALEGRADAPQADPAAAGG
                     PAAGAGGALGSLLALNRNRNRNRNRNRNRNRNRNRNRNRNRDAGNLDTDGGLGILEPWE
                     ERQALYEILGEWDGLPLQPPPTMEQLRHECIDLLVKQHLRTQSEAATRRDEIFREASLE
                     LSGYLRPLGIEEYGGYGATVALFLTVLALTDEIGLRFKDRFSLLRPNQAEPRLRPCLPN
                     PAHASYPSNHSFQSFSIAFIFSRMLPEHPGSAELFHSARRIAENREWAGVHYASDSRAG
                     YELARMIAPVLEKVLRKQMLAAYQEWI"
     gene            complement(7117..8889)
                     /locus_tag="RIdsm_RS06345"
                     /old_locus_tag="RIdsm_01277"
     CDS             complement(7117..8889)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RIdsm_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RIdsm_01277"
                     /product="hypothetical protein"
                     /protein_id="WP_057814598.1"
                     /transl_table=11
                     /translation="MTLVQDIDASQAANDRPPRLRMYLLGPFALTDTRFGRITPKGQKA
                     QGLLALLALAPRNERTRVWLRDRLWSGSNQKRAATNLRQTVFELKRDLGELIDDILVID
                     SKTISLRADTLWVDAWALDDTPGLYGKLALNPDTQLLEGMDIADEEFEDWLRTERTLWT
                     DKLTRMAETSPRTPASGLALPARPDPQPLLQRMAPPNPSKLCIGYLPSIQHGCDDSTMY
                     LADFILEGIARNLKELEPVNIYDFRNATLPSDTLTGAVEVEYYVRLRTLQIGEAMTFTF
                     FLYRAPNMILEWSQSIQAQRRDVIEDDFGLMHGFISQNVDRLARFLFERRGTPGGQPPP
                     PQQVAYTALNLMFRLDDNALDNAQTLLDAAQDISPDPIYPALKCYGLSFKLGENVGQLA
                     SGEAEETRALVREVLQGNPFNSITLASLGHVLGYGFGDHAAAATLLNRAVELNPTQAFV
                     WDHYALHKLYTGEIDAAYDAARRAVRLGAYSPLRFGFDTTLCMTAMLKGELGQAVTSGR
                     AALTRQPRFSAAMRYLTATYGLQNRPEEARGIYDRLLIEDPDFSDPEIRRKRFRVLHRE
                     TEDQILRGLNVCGL"
     misc_feature    9020..9035
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.63"
                     /tool="antismash"
     gene            9307..9597
                     /locus_tag="RIdsm_RS06350"
                     /old_locus_tag="RIdsm_01278"
     CDS             9307..9597
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RIdsm_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RIdsm_01278"
                     /product="hypothetical protein"
                     /protein_id="WP_057814600.1"
                     /transl_table=11
                     /translation="MADTKVAALEAKIAELEGRIRGVNPSVIDKIGSLANFSAGSCTNE
                     CTAACTIGCTKGCTGTCVTQEPELDVEVATTVVDQGEVARGVNLFNSLAKR"
     gene            9683..9973
                     /locus_tag="RIdsm_RS06355"
                     /old_locus_tag="RIdsm_01279"
     CDS             9683..9973
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RIdsm_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RIdsm_01279"
                     /product="hypothetical protein"
                     /protein_id="WP_057814602.1"
                     /transl_table=11
                     /translation="MKKIHLLEMQLTNLELQIRNLQLVQGLVSEARTHGCTGGCTGSCP
                     DPTGDCTYGCTNGCTNGCTDGCNDEVGGVFGPDDLVGDPGDPGGPQGPGKS"
     gene            10001..11206
                     /locus_tag="RIdsm_RS06360"
                     /old_locus_tag="RIdsm_01280"
     CDS             10001..11206
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.4"
                     /locus_tag="RIdsm_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01280"
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_057814604.1"
                     /sec_met_domain="LANC_like (E-value: 1.3e-16, bitscore:
                     58.6, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTETGAALPPQETHDSAARLAREALHLFAATPQSRDMPWDPGPM
                     VLADHARLEAGQLETTSAAWLERIPAPPGPFSVFAGHAGLVMGLWHLSRAGLPDQAVMK
                     RTHARLRDELLLASRRAGWARPVRDWYDYDLVTGPAGLLLSMLPDGAVEAEQLAPVVAH
                     LVGLLEAEDLAGLRPDGCGADAQRRWNLGRVNLGLAHGVPGVIAALSGYIRRYAPEDER
                     VYMALERATGWLIAQAHRDRRGLTTWAPGSEAGLPDPAPASHREAWCYGAPANAWVIWE
                     AGDVLDRPAFRSFALETFHAYASRFDPAFHLDRDPLERLAICHGAAGIMLIADAFVRHA
                     GFAPAEALRGATRELVEPRLGDVPAMMVANPTMLSGASGILSAIFTIQGGRRDWLSALG
                     LR"
     gene            11203..12225
                     /locus_tag="RIdsm_RS06365"
                     /old_locus_tag="RIdsm_01281"
     CDS             11203..12225
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF025394.4"
                     /locus_tag="RIdsm_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01281"
                     /product="thiopeptide-type bacteriocin biosynthesis
                     protein"
                     /protein_id="WP_057814606.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.1e-13, bitscore:
                     49.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTHQMTNFLCDPRDEPVLSLKNETLALNHIATLMGAEAERAVLNG
                     APDEARLALARCVFREAGMAAVAQFYENDGWVQLGLSPCPGMRAALYREVEKLPARLRG
                     RFQVRAAFFMHKPPGLRLRVQAALTDAGALGFEMADAARGWREAGLVSDVREEIYEPET
                     TLFGGAGSMRHVHGLFSEDSGFWLAHHARPEQGERTLEVALILLRYVFSGLGVVDWEDI
                     DVWEKVRSRTGRAFPAGFDADGSALGEVGATILRLWSEPGGVLRALDARTRARTERAGA
                     RLVKLAADWKAECFDAGRAGTGVRSAAALYTIFFFNRAGLPLERQIIVAETLASRQVME
                     "
     gene            12240..14675
                     /locus_tag="RIdsm_RS06370"
                     /old_locus_tag="RIdsm_01282"
     CDS             12240..14675
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="RIdsm_RS06370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="RIdsm_01282"
                     /product="hypothetical protein"
                     /protein_id="WP_143100443.1"
                     /transl_table=11
                     /translation="MSDTAVATCVMMRVCAVPLELYREAVPPDLHGLLLEHEACRAGLE
                     RAAEAAVAALDDVVNAGGWSREETKKLGTLRRRVARRAPPQPVDGETLGWLAERAAPLA
                     AEIEGVFGALARRDGLLDEIAARLEAGAEAVLPEVWARIAGAPALAALVREHDAAFFGL
                     CSEGAEEAGFWSGKRGRHRAKYLKTILQRGTFRTVPRGWYTYAGFAAVQGGPTGPLVVA
                     ARKAASHAVNFHDLRRRASEDWAEGDDVPLMLSPLNWRDGERIGFCVSGWANPAKVSEI
                     SLRRSDFLGRVLEAMEGHVLSAKEIAGRMDGAVTPEETEILPAFLAHLLEKGVVQACPQ
                     AGQSLSGWAAPGRLSAPAHIRARPHSFTDVYTGIEGAVSADQLERVQAGMADVARLSAL
                     IEGDRAGQAGPGDARAASGSVPLLSVVRARLLKEERAGGAPVPSGGTPAAFRACDWPLP
                     SSRQGAYARLHGHIGSRLGGAGPITLPGALLEGGGAAPVWPRDAMVRLAGPAAGFCGVF
                     DESFVAGSMDARFLWAAERLGHDLPQKAFYEEFLTALQGDHGIRFVELLFPPLSLGAAN
                     AVIRPRYLDRWTGDPDCGSYFQSETAGMEFLSLERFGIERTARGQRLTCDGERIFAMYH
                     ATRLPLPPWDVLTNQMLNAAPPFMRVSSRRLHRVLDAFPEAASAPPVQTESGLVVSCAQ
                     WRLRPEEHWAPEDGLLDKMRGLARLRRDRGVPRFVFLSPGPGLRPEVCDLDDPLSPRKI
                     EEVAETAPDLLAIAMTPDETTSLVKSALGTHAACALVRYPLGRGPGALAEGAAAELKW"
     gene            complement(14692..15357)
                     /locus_tag="RIdsm_RS06375"
                     /old_locus_tag="RIdsm_01283"
     CDS             complement(14692..15357)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1071: GntR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019349.4"
                     /locus_tag="RIdsm_RS06375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01283"
                     /product="GntR family transcriptional regulator"
                     /protein_id="WP_064261385.1"
                     /transl_table=11
                     /translation="MERVAAPLRIQVIEAIRNAIVAGRFSPGERLLERRLCEMVGVSRT
                     LIREALRQLESEGLIDVVPHRGPVVAKIESSMARDIYMVRSELEGLAAAIFAERATEDD
                     LQALREAYEGLKAISGSSDPVVRVAAKNRFYEKLIEGSGNKALGPSLNFLNSRILLLRA
                     TSLKAGGRLDKSIEELGELLEALEARDPERAKKAAQAHVAKAAEISLKFLAEAEAKEA"
     misc_feature    15424..15444
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 22.78"
                     /tool="antismash"
     misc_feature    15478..15493
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 19.18"
                     /tool="antismash"
     gene            complement(15513..16553)
                     /gene="dctP"
                     /locus_tag="RIdsm_RS06380"
                     /old_locus_tag="RIdsm_01284"
     CDS             complement(15513..16553)
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="dctP"
                     /inference="COORDINATES: protein motif:HMM:NF015445.4"
                     /locus_tag="RIdsm_RS06380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01284"
                     /product="TRAP transporter substrate-binding protein DctP"
                     /protein_id="WP_057814612.1"
                     /transl_table=11
                     /translation="MTISLKSTARGVMGAAALGLSLTAGQAVAQEPEFDFTMAVIVSPG
                     DVYTALTQGIPERIDEATDGRVQITVSDSLVASNQVAGAVRDGRVPMSAALHTYISAED
                     PRMGIFNLPGLINGIDDYVEVREAFWREDVKNIWKENWNAEMLADGAWCPTALFSKEPI
                     HEVADFEGKRIRIHNPQSAALMSSLGAKPIPMPTSEVTPALERGVIDGVFTSMCVGAAM
                     ELPRVAPHVQDWAISPITGWVILVNADTWAELPEDVRGQISQAMAELEEEAFGTYQTYI
                     DTAKEKFAELGSELWVAPKELQEEVSSEQYSAAAFEGWYDRAEEIGVDGQAYVEQIREA
                     LGREGS"
     misc_feature    complement(16716..16731)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.73"
                     /tool="antismash"
     gene            16729..18786
                     /locus_tag="RIdsm_RS06385"
                     /old_locus_tag="RIdsm_01285"
     CDS             16729..18786
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0031317 - tripartite ATP-independent
                     periplasmic transporter complex [Evidence IEA]"
                     /GO_function="GO:0015556 - C4-dicarboxylate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015740 - C4-dicarboxylate transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018513.4"
                     /locus_tag="RIdsm_RS06385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01285"
                     /product="TRAP transporter large permease subunit"
                     /protein_id="WP_057814613.1"
                     /transl_table=11
                     /translation="MSNDTTLSVPQGGSDGNLFIASVRGLTQLAGLLAAMTLLFMTLIV
                     FYEVVMRSVFNAPTSWVAEISVYSFVAMVFFGMGVAQTKGAHIRVEVLLDSVKDETRTL
                     LMLLGDWLLLVLVALSGWEMFCFTVSEFINGTRDWGLLATPQWIPETPVVIGYALFFFS
                     ILQTAFDERAPKTEARIWAAPAIVLAAIGALALIGRRDWFPFDWLPVDMATLVITAAIL
                     LIAALWSGARIAGILLGLLVVMAVLFSYAQDASLVFTGVLMTVSLLGLLLLGVPVGGTL
                     GMVGLMGLAFTLNNPQLPILADRSWTSINSFTLTAVPAFVLMGTLLVHSGVTVRLFDML
                     VCWFGRARGGLGHAAIGSSAIFAAVSGSSLATAATLGRVAAPELNSRGYSRRLTYGVVA
                     AGSTLGILVPPSIAMIIYGNTVGAPITVLFVAGVVPGLVLACLFALTILIWSYLSKEAV
                     PEGERYSMGEKFRSTLGVLPFLVLIAAVLGSLYFGIATPTEAGAVGAVAAFAICVAAGR
                     AAPMDIYHALTDTVKVTAFIMLIVVGASIFSWVFDFLRLPRELVSTVTEAELQPWLVML
                     LLAVFYLLMGTLIESISMMLMTLSVTFPIVVALGFDPIWFGVVLVLLVEIGLITPPVGI
                     VLFILRGLGDVSLRDITLGVIPFILVMLSMLVLLYFFPDIVLWLPEQMEG"
     gene            18820..19710
                     /locus_tag="RIdsm_RS06390"
                     /old_locus_tag="RIdsm_01286"
     CDS             18820..19710
                     /EC_number="1.1.-.-"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_function="GO:0051287 - NAD binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF015411.4"
                     /locus_tag="RIdsm_RS06390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01286"
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_057814615.1"
                     /transl_table=11
                     /translation="MSLKLGFVGIGRMGKPMAGHLLDAGYDLTVFDPNKSAVEALVAKG
                     AKAAESPKAVGDEAELILMSLPTPDVVTEAATGAEGISKGSKARAVIDLSTTGPTAARA
                     LAEGLKADGLGCVDSPVSGGVAGAEKGSLTLMTACTDELFAEVEPILKLFGKVTHVGQE
                     AGQAQLIKVINNLMSVTALAIASEGIVLAEKAGVSGETLMNVVNQGSGRSNASEDKIPK
                     YVLSRKFDFGFALGLSAKDVRLCIAESEALGVPMIVGSAAKMLMGIAHTQQGPDADLTE
                     LIKSVERLANVEQAS"
     gene            19707..21038
                     /locus_tag="RIdsm_RS06395"
                     /old_locus_tag="RIdsm_01287"
     CDS             19707..21038
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015905.4"
                     /locus_tag="RIdsm_RS06395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01287"
                     /product="MmgE/PrpD family protein"
                     /protein_id="WP_057814617.1"
                     /transl_table=11
                     /translation="MTEVTRALAEFAATAEVPEPVREEAKRSILNGLATGIAGAEDDAV
                     RIAQATLDRLEPGQGVGLIARDQEAGPLTAAFLNAMAINVHDFDDTHPGTILHSTAPVL
                     PVLLSLAAQQTVSGRAFLEAYAVGVEVECRVANAVSPGHYRRGWHITGTCGVFGAAAAA
                     GRILGLTAGQMVDAFGSASAQSSGLVETLGYMAKSVGVGGAARGGLLAAWLAKDGLSGP
                     AAPLEGPRGFLRVTSDAPDFEQAMPLIGGKWELMRITYKPYPCGVVLNPVIEAALTLGG
                     GKSHAPGEIASVTVTGHPLLAERADRPSPESGRTAQVSAQHAVAACFGRAAAGLPEFSD
                     AAVADAALTELRAKVVVVQDESYPVGAARVDVALADGGTRTETVDVAEGDLGRPLSTER
                     LQQKLADLVALGGSGCDPVAIAEAVLGLDRADDAAPILRLVRPG"
     gene            complement(21045..21824)
                     /locus_tag="RIdsm_RS06400"
                     /old_locus_tag="RIdsm_01288"
     CDS             complement(21045..21824)
                     /NRPS_PKS="Domain: PKS_KR (6-120). E-value: 3.5e-09. Score:
                     28.7. Matches aSDomain:
                     nrpspksdomains_RIdsm_RS06400_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024950.4"
                     /locus_tag="RIdsm_RS06400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="RIdsm_01288"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_057814619.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 2.5e-05, bitscore:
                     21.8, seeds: 37, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLNGKTCLVTGAAGGIGSALTKLFLSQGAQVIATDLDLAALETK
                     FADAKTDTLHLRALDITDPTAIAALNDSLEAENLPINVLVNNAAAIRIGALLDASPEDL
                     DLVYRVNMRGTMMMMQGFMPGMIARGGGTILNMASLAGVHAMYERFAYGASKAAIVMMT
                     RSVAVDYVAKGIRANCICAARVETPFIRSYLTEYYPDEVEERFEALSKYQPTGRMITAD
                     EVAQMAVYLCAEESAMVNGQAFTIDGGVTAGDRAPAT"
     aSDomain        complement(21465..21806)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_RIdsm_RS06400_PKS_KR.1"
                     /evalue="3.50E-09"
                     /label="RIdsm_RS06400_PKS_KR.1"
                     /locus_tag="RIdsm_RS06400"
                     /protein_end="120"
                     /protein_start="6"
                     /score="28.7"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TCLVTGAAGGIGSALTKLFLSQGAQVIATDLDLAALETKFADAKT
                     DTLHLRALDITDPTAIAALNDSLEAENLPINVLVNNAAAIRIGALLDASPEDLDLVYRV
                     NMRGTMMMMQ"
     CDS_motif       complement(21726..21806)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_RIdsm_RS06400_0001"
                     /evalue="4.80E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="RIdsm_RS06400"
                     /protein_end="33"
                     /protein_start="6"
                     /score="19.2"
                     /tool="antismash"
                     /translation="TCLVTGAAGGIGSALTKLFLSQGAQVI"
ORIGIN
        1 gcccgcggct gatcgacaag atcgataccg agcggcgcct caagacccag tggaacatcg
       61 acccccaccg ccagtcgatg cgtcaggcgc ttctctcgct gtcccatggc tcgaccgcga
      121 tccgcagcca cgtggatatc gacaccgaga tcggcctcgc cgggttcgag ggcgtggcgc
      181 agacccgcga taccctcaag gggcaggtcg acatcgagat cgtcgccttc ccgcaatcgg
      241 gcatgatgag ccgccccggc accgccgagc tgatggaaac cgcgctcgcg aacggcgccg
      301 aagtggtcgg cgggctcgac ccctgcggca tcgaccgcga ccccaagggt cagctcgacg
      361 ccgtcttcgc gctggccgag aaacacggca agccgatcga catccacctg cacgaacccg
      421 atgagctggg cgcgttttcg atggagatga tcctcgaccg gatccgcgcc cacggcatgc
      481 aggggcaggt cacgatcagc cacgccttct gtctcggcat ggctgatcgt gcccgcgccc
      541 acgggctgat ggagcggctg gccgaggaga aggttttcat cgccaccgtc gccacgccat
      601 cgcggcccgt gccgccagcg gcggagttgc gtgagcgcgg tatcaccctc tgcgcgggct
      661 ccgacggcat ccgcgacacg tgggggccct atggcaatgc cgacatgctg gaacgtgcca
      721 tgctgctggg attgcgcaac aatttccgca ccgacccgga tgtcgaacat gcgctctggt
      781 gctgctccta tggcggggcc gaggtgatgg ggctcgaggg ttacggcctg accgaaggca
      841 gcgccgccga tctcgtgctg gtcgatgccg aggccgtggc gcatgccgtc gtcgcccacc
      901 cgccgcgccg gctggtgctc aagggcggcg ccgtggtggc ccgcgacggc cagaccctga
      961 ccgaggcccc gtgatgccgg cacaggaaca aggcaccacg ctgatgacgg cccgctgggt
     1021 cgtcggccac gaagacgggc ggcacgtgct gttcgagaac ggcgaagtgg cgttcgagaa
     1081 cgggcggatt acctttgtcg ggcatggttt ccccggcgag gccgcccggc ggatcgactg
     1141 cggcgatgcg gtgctcggcc ccggcttcat cgatctcgac gcgctgtccg atctcgacac
     1201 caccgtgctt ggcttcgaca atcagccggc ttggaagaaa ggccgggtct ggcccgcaag
     1261 ctatatgcgc gccggcccgc gagagatgta cacgcccgag gatctggcct ggcagaagcg
     1321 ctatgctttt acacgcctga tccgaaacgg aattaccacg gcgttgccca tcgcctccct
     1381 attctaccgc gaatggggag agacgcccga agagtttgcc gctgcggccg acgcggcaga
     1441 ggagcttggg ctgcgggtct acctggggcc agcctatcgg accgggaaca ctttcgtcac
     1501 cgatgatgga gagatcgatt tccatttcga cgaggcccgt gggctcgatg gtctgaaggc
     1561 ggcggaagcc ttttgccgcg atcatgaagg ccgggccggc gggctgatcc gcaccatgct
     1621 tgcccctgac cggatcgaga cctgcaccga ggaattgctg cgccggacag ctgctgcctc
     1681 tgccgacttg ggcgtgcccg tgcggctgca ttgctgtcag tcggtcttcg aatatgaaag
     1741 cgtgttgcgt atgcacggga aaagcccgcc ggaatggctg ttgagcctcg gtttcctgtc
     1801 ggagcgcagc atcctgccgc acctgaccgt catctcgggg cgcaacggta tcacccacga
     1861 cgggcctgac cttcagatcc tcgccgactc gggggccagt ctggcccatt gcccgctggt
     1921 gatggcgcgg ggcgggctgg cgcttgatga cttcgccacc taccgcgaag caggcctgac
     1981 catcggtatg ggcacggata cgcacccgcc tgacatgatt ttgaacatgc aggcggggct
     2041 gctgatgggc cggctgagcg cgggtcgccc gcaggcggtg cgttcagagg acatgtacga
     2101 cgcggcgacg cttggcgggg ccaaggcgct gggccggtcc gatcttggcc ggctggagcc
     2161 gggcgcctgt gccgatatca ccgtgatcgg gctggacgac ccggcgatgg ggcaggtgat
     2221 cgacccgatc cagacgctga tgctcaacgg ctcgggccgc gacgtgcgta ccgtggtgat
     2281 tgacgggcgc gtggtgatgc gcgacggggt gatcccgggg gtggacgagg cggcgatgca
     2341 ggtgcaggcg caggcccagt tcgacgggct tgtccggcaa taccccgacc ggacgcatgg
     2401 gcatccgccg ttatccgata ttttctcgtc aagttacccg cttcggaggg ctgcctcatg
     2461 accgacctgc tgatccgcaa tgtgaccgcc gtgaccgtgg atgcggggcg ccgggtgatc
     2521 gagaatgccg ccattgccgt gcgtggggac cggatcgttt acgtcgggtc tgatgccgat
     2581 cttccggctg agtttgaggc ggcgaggaag gtgatcgacg ggcacggaat ggcggcgatg
     2641 ccggggttga tcgacagcca ttcccatgcg gggcacgggc ttgtccgctc gctcggggcg
     2701 ggcaataccg aggtctggtt tcaggcgtgc gaggagattt acgcgcgcgg ctcgacggtg
     2761 gatttctggc gcgccgaggc ggaactggcg cagctggaac ggctgatggc gggcgtgacg
     2821 accaacctga ccttgctggg gggcggggcc gatatctatc gcacggacga cccggtttat
     2881 ggcgatgcgc attgtgcggc gaccacggct tcggggcttc gtaccgtgct ggccgtgggg
     2941 ccggggcgac cgccttttcc caagccatac aaggcgttgc agaacggcga ggcacaggat
     3001 gtacgcctga gcttcgcgcg gcagatggag gtgagcgagg acctgatccg ccggcatgat
     3061 ggcgtgctgg acaagcgcac cggcatcgcg ctgatcatgc cggtttacca cgcgcatcac
     3121 atggaggacg ccgctgatgc gaaggcgatc cgcgagatgt ctgaggtcgt ggccgacatg
     3181 cgggcgcggc acggggtgct ctacacgcag gacggccatc gcgacgggac catcgcgctg
     3241 gcgcaggggc ttggcacgct ggggcctttc gcgctgttgt cgcatagcgt cgacctgacc
     3301 gacgcggatt tcgcggcgct gcggaagacg ggggccagta tcgttcacaa cccgacggcg
     3361 atcatgtcga tctatggtcg ctgcccggcg ccggagctga tcgacgcggg ggttcgggtc
     3421 gtgctgggct cggatgccgg ggcgccggac cgggggttcg acatgttccg gcacatgaag
     3481 caggcgatgc tgtatcaccg ccgtcacttc gccgatccgg catatatgcc gcccggcaag
     3541 gtgctggaaa tggcgacgat cgacgcggcc gacgcgcttg ggctgggcga cgagctgggc
     3601 tcgatcgaga ctggaaagaa agccgacatc atattgatag atatgaaaaa accgcatctc
     3661 tccccggtca acatgccgct gacccggatc actcatttcg ccaccgcggc ggatgtggat
     3721 accgtgctgg tcgacgggcg tgtggtgatg gaggggcggc aggtgaggac gctggagccg
     3781 ggggcggtga tggaggccgc cggggtggag ctggcgaagg cgctggagcg cacagggctg
     3841 acggcgctga cggaggagcc tgcgggcatg tggggggcga cgcggtttgc cgggggggag
     3901 gcgggctcat gaaaatccac gtggtgaacc ccaattcgac cgccgcgatg acccgcacga
     3961 ttgccgagac ggcgcgggcg gtggcgcggg ccggaacgac gatcacggcc agcaacccgg
     4021 cgcatgggcc ggcgagcatt cagggctatt acgacgtggc cgcctgcatg ccggggctgt
     4081 tggaggaagc aggccggcac cgggatgcgg atgcggtcat cgtggcctgt ttcgacgata
     4141 ccggcgtcga tgccttgcgg gcgatgctgg atgttccggt catcggaata ggcgaggccg
     4201 cctatcatgc ggcaagcctg atttccacgc gattctcggt ggttacgacc ttgccgcgct
     4261 cggttccggg gctggaggcg aaccttgtgc gctatggctt gatggcgcgc tgtggctcgg
     4321 tgcgggcgag ccgtgtgccg gttctcgacc tggagaaacc ggggggagag gccgagcggc
     4381 tgatcgccgc ggaggtgcgg cttgcggtcg aggaggacat ggcggaatgc atcgtgctgg
     4441 gctgtgcggg gatggcggag atgcgggcgc gtctggcgga ggcgttcggc attccggtca
     4501 tcgacgggat cggctgcgcg gtggggttcg tcgagacgct ggtggccgcg gggctgagca
     4561 cgtcgaaggc ggggggctat gcctcgccgt tcgtggcgga gatggcgtga gattttccgg
     4621 ttaacgaggc ggtttcgggc atttgggcgc gaatcagggt taatgccctg attttgcgtg
     4681 aaaaccgcat gtcggtatcg cgtcggtata acgtcggtat tacgtcggtg ttttttcccg
     4741 acgcgaggcg ggttaacgca ccgcgcgggc ggtgcgccgg gcccgttcag gccggggcgg
     4801 ttgccggcgg ggtttcggcg ggcgccgggc tgtcgggaaa ggacagctcg ccgttccagg
     4861 ccggaacggt gatttcctga ccggcgcgcg agaccttgac gcccaaggtg agcaggaagc
     4921 tcttggcctc gatcccgtcg gcgtcgggag acaggcggcc cgtggagcgg gccagcgaca
     4981 ggacccccgc gacgatggcc gaggcggcgg aggtgccgcc gaagcggcag aaataggagc
     5041 cgaattcgcg caggccgatt tccggctcgt cgcccaggaa cgggccgcca gcatagccgt
     5101 agatgcccgg cacgtcggtg ctgatgatgt cgaaggcgga gaatttctcg ttcgaggcag
     5161 ccgaggcatg ggcgggcaag gtctgatctg cgcggtgcgg atcgaggcgg atttcgcccc
     5221 ggtcgtaggt ttcgccgtca tcgcttggcc cgcagagcgt gacgtggcgg gtgtcggaat
     5281 agctgctgcc gacacccttg gcgttgatcg cgccgaccga gatgatgccg ttatgttcgg
     5341 aggcgaggtt ggcggggtag atgccgtgct cctcgttgct gttgccggcg gcgcagacga
     5401 tggggcgctg atgcgagacc tgcaccagaa gcgtggcgag ttcttcccac atctcgagct
     5461 cggccggggt gatggcggtg ggggccacga ggtcgcgcag ggcatggtcg ctgatcatcc
     5521 ggttgagctc gggcacggtg cggctggggt cggagatggt gcgggggatc aggacgacat
     5581 cggcgtcgat cagctcggca tagagcaggg cgaggatgag ctgctcgggg tcgggattgt
     5641 agttggtcga gatcgggacg atctcgcaat gcgggtcgac gccggcatag ggcaggggga
     5701 cgttgtcgtg accggggacg gggcttgggt agccgtcggc ggcgcgggcg atggcgggcc
     5761 gggcgccgac aaggccgcag atggccgtgc cgtgagaaga gaagtcggcc cccgtcatcg
     5821 gctggatgcc gtcgagccag gcggtgccgt catgcgacag ccggtcgacc atctcggcca
     5881 gcagctcgga ggcgcggggc aggccatcga cgacgggcgt gccggcgttg aggtcgaggg
     5941 cgccgatcct ggcggtaccg tcgcgatagg ggaaggcgcc gaggcgtgtc gagaagaggt
     6001 cgagcgcgag gtcgcggttg atggcggggc gcaggttggg gtggtcggcc gcgacggaag
     6061 tgtcgatcac cgccacgcgg gtggggcgcg gggcgtcggg tgcgacctgc cagccgttgg
     6121 gcgcgtgatc gggcgtcagg atgccgaggg ccacgagatg ccagagcgcg tcgtaatcgg
     6181 ggtgtgtttc gggtttggtc atggtctcag atccattcct ggtaggcggc gagcatctgc
     6241 ttgcggagga ctttttcgag caccggcgcg atcatccggg cgagttcgta gccggcgcgg
     6301 gagtcggagg cgtagtgcac cccggcccat tcgcggttct cggcgatccg ccgggcgctg
     6361 tggaaaagct cggcgctgcc cgggtgttcg ggaagcatgc gcgagaagat gaaggcgatc
     6421 gagaaggact ggaacgaatg gttgcttgga taggaggcgt gcgcggggtt gggcaggcag
     6481 ggcctgagcc tcggttcggc ctggttcggg cgcaggaggc tgaaccggtc cttgaagcgc
     6541 aggccgatct cgtcggtgag ggcgagcacg gtgaggaaaa gcgcgaccgt ggcgccgtag
     6601 ccgccgtatt cctcgatgcc gagggggcgg aggtagcctg agagctcgag gctggcttcg
     6661 cggaagatct cgtcgcggcg ggtggcggcc tcggactggg tgcgcaggtg ctgcttgacc
     6721 agaaggtcga tgcattcgtg gcgcagctgt tccatcgtgg ggggcggttg caggggcagg
     6781 ccatcccatt caccgaggat ctcgtagagc gcctgccgtt cttcccaggg ctcgaggatg
     6841 ccgaggccgc catcggtgtc gaggttgccg gcgtcgcggt tgcggttgcg attcctgttg
     6901 cgattgcggt ttcggttccg attgcggttc cggttcctgt tgcggttccg gttcagtgcc
     6961 agaaggctgc caagggcgcc gcccgcgccg gccgcggggc cgccggcggc ggccgggtcg
     7021 gcctgtggcg catcggcccg gccttcgagg gccagccctg cggcggttac cacgagccgg
     7081 tgccgctgaa gcagcccggc ggtgttcagt tcctgatcat aatccacaaa cattcagccc
     7141 cctgagtatc tggtcttcgg tttcccggtg caggacgcgg aaccgcttgc ggcggatctc
     7201 cgggtcgctg aaatccggat cttcgatgag caaccggtcg tagatgccgc gcgcctcttc
     7261 cgggcggttc tgcaggccgt aggttgcggt gaggtatcgc atcgccgccg agaagcgcgg
     7321 ctggcgggtg agggcggcgc ggccggaggt gacggcctgg cccagctcgc ccttgagcat
     7381 ggcggtcatg cagagcgtgg tgtcgaagcc gaagcgcagc gggctgtacg cgcccagccg
     7441 gacggcgcgg cgggcggcgt cataggcggc gtcgatctcg ccggtgtaga gcttgtggag
     7501 cgcgtagtga tcccagacga aggcctgggt ggggttcagc tcgaccgccc tgttcagcag
     7561 ggtggcggcg gccgcgtgat cgccgaagcc gtagcccagc acgtggccga ggctggcgag
     7621 cgtgatgctg ttgaaggggt tgccctggag cacctcgcgg acgagggcgc gggtttcctc
     7681 ggcctcgccc gaggcgagct ggccgacgtt ttcgcccagc ttgaaggaga ggccgtagca
     7741 tttcagggcc gggtagatcg ggtcggggga gatgtcctgg gccgcgtcga ggagggtctg
     7801 ggcgttgtcg agcgcgttgt cgtcgaggcg gaacatgagg ttgagggcgg tgtaggccac
     7861 ctgttgcggc gggggcggct ggccgccggg ggtgccgcgg cgttcgaaga ggaaccgggc
     7921 gaggcggtcg acattctgcg agatgaagcc gtgcatgagg ccgaaatcgt cctcgatcac
     7981 gtcgcggcgc tgggcctgga tggactggga ccattcgagg atcatgttgg gcgcgcggta
     8041 gaggaagaag gtgaaggtca tcgcctcgcc gatctggagc gtgcgcaggc ggacgtaata
     8101 ttcgacctcg acggcgccgg tgagcgtgtc gctgggcaag gtggcgttgc ggaagtcgta
     8161 gatgttgacg ggttcgagct ccttgaggtt gcgggcgatg ccctcgagga tgaaatcggc
     8221 caggtacatg gtgctgtcgt cgcagccgtg ctggatgctg ggcaggtagc cgatgcagag
     8281 tttcgagggg ttggggggcg ccatgcgttg cagcaagggc tgcggatccg gccgggcggg
     8341 cagggccagg cccgaggcgg gggtgcgggg cgaggtttcc gccatccggg tgagcttgtc
     8401 ggtccagagg gtgcgctccg tgcggagcca gtcctcgaat tcctcgtcgg cgatatccat
     8461 gccttcgaga agctgggtgt cggggttgag cgccagtttg ccgtagaggc cgggggtgtc
     8521 gtcgagcgcc caggcatcga cccagagcgt gtcggcccgc aggctgatgg tcttgctgtc
     8581 gatgacgagg atatcgtcga tcagttcgcc caggtcgcgt ttcagctcga agacggtctg
     8641 gcggaggttg gtggcggcgc gtttctggtt gctgccgctc cagagccggt cgcggagcca
     8701 gacgcgggtg cgttcgttgc ggggggccag cgccagcagg gcgagaaggc cctgcgcctt
     8761 ctggcccttg ggcgtgatgc ggccgaaccg ggtgtcggta agcgcgaagg gcccgaggag
     8821 gtacatgcgc agccgcggcg gccggtcgtt cgcggcctgc gatgcgtcga tgtcctggac
     8881 cagtgtcacg gaacgaccct ttcgtcggtc tgagaatcgg agtgcgacac aacttgagca
     8941 cgaaataatg gcaaaaccgg gaaaccgacc gtagaccttt gaaaccgctg ccgaactcac
     9001 tcgcagtcac tcctgttcaa ctgcgaatca tccttggtaa tctggcgtta tgggagcgtt
     9061 aggcgcggcg cctgccgggc gttatgcgcc ggttttccgt ctgttggccc gcggacaccc
     9121 ccacaccaag aagctgaaac cctttcactt ttacacccgt atggcgtgta tcggtgcgtc
     9181 ggtaaatgcc taacctttcc ctaacgtcaa tttcggcagg tttgtactca gccgggcggt
     9241 cggatggccg caaaccacgc ggccccggcg cgacggcaca tttgaaacct catcaggaga
     9301 agacccatgg ctgataccaa agttgccgct ctcgaagcga aaatcgcaga actcgaaggc
     9361 cgcattcgcg gcgtgaaccc ttcggtgatc gacaagatcg gctcgctggc gaatttcagc
     9421 gccggcagct gcacgaacga gtgcaccgcc gcctgtacca tcggctgcac caagggctgc
     9481 accgggacct gtgtcacgca ggaacccgag ctcgatgtcg aggtggccac cacggtcgtg
     9541 gaccagggcg aggtcgcgcg cggcgtgaac ctcttcaaca gcctcgcgaa gcggtaagcc
     9601 ccggcggccc ggcccggcgg cggtgccgtc gggcctatcc cgcggagatt tcctgtcacc
     9661 ctcaaccgaa cggggacgtc ccatgaaaaa gatacatctg ctcgaaatgc agctgaccaa
     9721 tctcgaactg cagatccgca accttcagct tgtgcagggc ctcgtttcgg aagcccgcac
     9781 ccatggctgc accgggggtt gcaccggaag ctgccccgac ccgacaggcg attgcaccta
     9841 tggctgcacc aacggctgca ccaatggctg taccgacggg tgcaatgacg aggtgggcgg
     9901 ggtgttcggc cccgatgacc ttgtcggcga tccgggcgat ccgggcgggc cgcaggggcc
     9961 gggcaagtcg taagccggac caatcacagg gagagaacag atgctgaccg aaaccggggc
    10021 ggcgctgccg ccgcaggaga cacacgatag cgccgcgcgc ctggcgcgcg aggcactgca
    10081 ccttttcgcc gcgacgcccc agtcgcggga catgccgtgg gacccggggc ccatggtgct
    10141 ggccgatcat gccaggcttg aggcgggcca gctcgagacg accagcgcgg cctggttgga
    10201 gcggataccg gcgcctcccg gcccgttttc cgtcttcgcc ggtcacgcgg gcctggtcat
    10261 ggggctttgg catctctccc gtgccgggct gcctgaccag gccgttatga aacgaacaca
    10321 tgcccggttg cgcgacgagc tgcttctggc gagccgccgg gccggctggg cccggccggt
    10381 cagggactgg tacgattacg acctggtgac ggggccggcg gggctgttgc tgtcgatgct
    10441 gcccgacggg gcggtcgagg cggagcaact ggcgccggtg gtggcgcatt tggtgggtct
    10501 gctggaggcg gaggaccttg ccgggctgcg gccggacggg tgcggggcgg atgcgcaaag
    10561 gcggtggaac cttggccggg tgaaccttgg gctggcccac ggggtgcccg gggtgattgc
    10621 ggcgctgagc gggtatatcc ggcgttatgc gccggaggat gagcgggttt acatggcgct
    10681 ggagcgggcg accgggtggc tgatcgcgca ggcgcatcgt gaccggcggg ggctgacgac
    10741 atgggcgccc ggttctgagg ccgggttgcc ggacccggcc ccggcgagcc atcgcgaggc
    10801 gtggtgctat ggcgcgccgg cgaatgcctg ggtgatctgg gaggcggggg atgtgctgga
    10861 ccgcccggcg ttccggagct ttgcgctgga aaccttccat gcctatgcca gccggttcga
    10921 cccggccttt cacctggatc gggacccgct ggaacggctg gccatctgtc atggggcggc
    10981 ggggatcatg ctgatcgccg atgccttcgt gcggcatgcg gggtttgccc cggccgaggc
    11041 gttgcgcggg gcgacgcggg agcttgtcga gccccggctg ggcgatgtgc cggcgatgat
    11101 ggtcgccaac cccaccatgc tgagcggggc gagcggcatc ctgtcggcga ttttcaccat
    11161 tcaaggaggg cggcgcgact ggctgtcggc gctgggattg agatgacaca tcagatgacg
    11221 aatttcctgt gcgatccgcg ggacgagccc gtgctgtcgc tgaagaacga aacgctggcg
    11281 ttgaaccata tcgcgacgct gatgggggcc gaggccgaaa gggccgtgct gaacggtgcg
    11341 ccggacgagg cgcggctggc gctggcgcgc tgcgtgttcc gcgaggccgg gatggcggcg
    11401 gtggcgcagt tctacgagaa cgacggctgg gttcagcttg ggctgagccc ctgcccgggg
    11461 atgcgagcgg cgctgtaccg ggaggttgaa aagctgccgg cgcggctgcg tgggcggttc
    11521 caggtgcggg cggcgttctt catgcacaag ccgccggggc ttcggcttcg ggtgcaggcg
    11581 gcgctgacgg atgccggggc gctgggcttc gagatggcgg acgcggccag gggctggcgc
    11641 gaggcgggtc tcgtttcgga tgtgcgggag gagatctacg agccggagac cactctcttt
    11701 ggcggggcgg ggtcgatgcg gcatgtgcac gggctgttct cggaggatag cgggttctgg
    11761 ctggcgcatc acgccaggcc cgagcagggg gagcggacgc tggaggtggc gctgatcctg
    11821 ttgcggtacg tgttctcggg gctgggcgtg gtcgactggg aggatatcga cgtctgggag
    11881 aaggtgcggt cgcgcaccgg gcgggcgttt ccggcggggt tcgacgcgga tggcagtgcg
    11941 ctgggcgagg tcggggcgac gatcctgcgg ctgtggtcgg agccgggcgg ggtgttgcgc
    12001 gcgctcgatg cgcggacgcg ggcgcggacg gaacgggccg gggcgcggct ggtgaagctg
    12061 gcggcggact ggaaggccga gtgtttcgat gcggggcggg ccgggaccgg ggtgcggtcg
    12121 gccgcggcgc tttacacgat cttctttttc aaccgcgcgg ggctgccgct ggagcggcag
    12181 atcatcgtgg cggaaacgct ggccagccga caggtgatgg aatgaaggat atgcatgttg
    12241 tgtctgacac ggccgtggcg acctgcgtga tgatgcgggt ttgtgcggtg ccgctggagc
    12301 tgtaccggga ggcggtgccg cccgatctgc atgggctgtt gctggagcac gaggcgtgcc
    12361 gggccgggct ggagagggcg gcggaggcgg cggttgcggc gcttgatgac gtggtcaatg
    12421 ccggtggctg gagccgggag gagaccaaga agctgggcac gctgcgccgg cgggtggcgc
    12481 ggcgggcgcc gccgcagccg gtggatggcg agacgctggg ctggctggcg gagcgggctg
    12541 cgccgctggc ggcggagatc gagggggtgt tcggggcgct ggcgaggcgc gacgggctgc
    12601 tggacgagat cgcggcaagg ttggaggcgg gggccgaggc ggtgctgccg gaggtctggg
    12661 cgcggatcgc gggggcgccg gcgctggcgg cgctggtgag ggaacatgat gcggcgttct
    12721 tcgggctgtg ttcggagggg gcggaggagg ccgggttctg gagcggcaag cgggggcggc
    12781 accgggcgaa gtatctcaag acgatcctgc aaagggggac gttccggacg gtgccgcgcg
    12841 ggtggtacac ttatgcaggg tttgcggctg ttcagggtgg cccgacgggc ccgctggtcg
    12901 tagccgcgcg aaaggcggca agccatgcgg tgaacttcca tgacctgcgg cggcgggcga
    12961 gcgaggattg ggcggagggg gacgacgtgc cgctgatgct gtcgccgctc aactggcggg
    13021 acggggagcg gataggcttt tgcgtctcgg gctgggcgaa cccggcgaag gtgtcggaga
    13081 tcagcctgcg gcgcagcgat ttcctggggc gcgtgctgga ggcgatggaa gggcacgtgc
    13141 tgtcggcgaa ggagattgcc gggcggatgg atggtgccgt gacgccggaa gagacggaga
    13201 tcctgccggc gttcctggct catctgctgg agaagggggt ggtgcaggcc tgtccgcagg
    13261 ccgggcagag cttgagcggg tgggccgcgc cggggcggct ttcggcgcca gcgcatatcc
    13321 gggctcggcc gcatagtttc acggatgtct ataccgggat cgagggggcg gtgagtgctg
    13381 accagcttga acgggtgcag gcgggaatgg cggatgtggc gcggctgtcg gccttgatcg
    13441 agggcgatcg ggccgggcag gcggggccgg gggatgcgcg ggctgcgagc gggagcgtgc
    13501 cgcttttgtc ggtggtccgg gcgcggcttc tgaaggagga gcgcgcaggt ggcgcgccgg
    13561 tgccgagcgg tgggacgcct gcggcgttcc gggcctgcga ctggccgttg ccgtcgtcga
    13621 ggcagggcgc ctatgcgcgg ctgcacgggc atatcgggtc gcgccttggc ggggcggggc
    13681 caatcacgct gccgggggcg ttgctggagg gcggcggtgc ggcgccggtc tggccgaggg
    13741 acgcgatggt caggctggcc gggccggcgg ccgggttctg tggggtcttc gacgaaagct
    13801 tcgtcgccgg gtcgatggat gcgcggtttc tttgggcggc ggagcggctg ggccatgacc
    13861 tgccgcagaa ggcgttttac gaggagttcc tgacggccct tcagggcgat catggcatcc
    13921 ggttcgtcga gctgctgttt ccgccgcttt ccctgggggc cgccaacgcg gtgatccggc
    13981 cgcgttacct ggaccgctgg acgggcgacc cggattgcgg aagctacttt cagtcggaga
    14041 cggcgggcat ggagttcctg tcgctcgagc ggttcggcat cgagcggacg gcgcgggggc
    14101 agcggctgac ctgcgacggg gaacggattt tcgcgatgta ccacgcgacc cggctgccgc
    14161 tgccgccctg ggacgttctg accaaccaga tgctgaacgc ggcgccgcca ttcatgcggg
    14221 tgtcgtcgcg gcggttgcac cgggtgctgg atgcatttcc ggaggcggcg tcggcgccgc
    14281 ccgttcagac ggaaagcggg ctggtggtgt cctgtgcgca gtggcggttg cggccggagg
    14341 agcattgggc gccggaagac gggctgctgg acaagatgcg cgggctggcg cggctgaggc
    14401 gggaccgggg cgtgccgcgt ttcgtgttcc tgtcgccggg gccggggctg cggccggagg
    14461 tgtgtgatct ggatgacccg ctgagcccgc ggaagatcga ggaggtggcc gagaccgcgc
    14521 cggacctgct ggcgatcgcg atgacgccgg acgagacgac gagccttgtg aagagcgcgc
    14581 tgggcacgca tgcggcctgt gcgctggtcc ggtatccgct ggggcggggg ccgggtgcgt
    14641 tggcggaagg ggcggcggcg gagctgaagt ggtgaagatg cgccgggctg gtcaggcttc
    14701 cttcgcctcg gcctcggcca ggaatttcag cgagatctcg gcggccttgg cgacatgggc
    14761 ctgcgcggcc ttcttggcgc gctcggggtc gcgggcttcg agggcttcga gcagttcgcc
    14821 gagttcctcg atggatttgt cgagccggcc gccggccttc agcgaggtgg cgcgcagcag
    14881 gaggatgcgg gaattgagga agttcaggct gggcccgagg gccttgttgc cggagccttc
    14941 gatcagtttc tcgtagaaac ggttcttggc ggcgacgcgg acgaccgggt cgctcgagcc
    15001 ggagatggcc ttgagccctt cataggcttc gcgcagggcc tgcaggtcgt cttcggtggc
    15061 gcgttcggcg aagatggcgg cggcgagccc ttcgagttcg gagcggacca tgtagatgtc
    15121 gcgggccatc gaggattcga tcttggcgac gaccgggccg cgatgcggga cgacgtcgat
    15181 cagaccctcg gattcgagct gacggagcgc ttcgcggatc agggtgcggc tgacgccgac
    15241 catttcgcac aggcggcgtt cgagaagccg ttcgccgggc gagaagcgcc ccgcgacgat
    15301 ggcgttgcgg atggcttcga tcacctgaat ccgcaggggc gcggcaacgc gttccacccg
    15361 gaattccgta ttcggatcgg ctgatttacc tgtcgtcacg atggcagcct tacgtttctg
    15421 acctgacaga gcataggcaa tctctgcgta gacgggaacc cctgcaaccc acaggggatc
    15481 ccgctttttt caagacgttg cacgacgtcg ggtcaggagc cttcgcggcc gagcgcttcg
    15541 cggatctgct cgacataggc ctggccgtcg acaccgattt cctcggcgcg gtcgtaccag
    15601 ccttcgaagg ccgcggccga gtattgctcg gagctgactt cttcctgaag ctctttcggg
    15661 gcgacccaga gttcggagcc gagttcggcg aatttctctt tggccgtgtc gatgtaggtc
    15721 tggtaggtgc cgaaggcttc ttcctcgagc tcggccatcg cctggctgat ctggccgcgc
    15781 acgtcttcgg gcagttcggc ccaggtgtcg gcgttcacga ggatgaccca gccggtgatc
    15841 ggcgagattg cccagtcctg cacgtggggt gcgacgcggg gcagttccat cgcggcgccg
    15901 acgcacatgg aggtgaagac gccgtcgatg acgccgcgct cgagtgccgg ggtgacttcg
    15961 gaggtgggca tcgggatcgg cttggcgccg agcgagctca tcagggcggc gctttgcggg
    16021 ttgtggatcc ggatgcgctt gccttcgaaa tcggcgacct cgtggatcgg ttccttggag
    16081 aagagggcgg tcgggcacca ggcgccgtcg gccagcatct cggcgttcca gttctctttc
    16141 cagatgttct tgacgtcttc gcgccagaac gcctcgcgca cctcgacata gtcgtcgatg
    16201 ccgttgatga ggccgggcag gttgaagatg cccatgcgcg gatcttcggc ggagatgtag
    16261 gtgtgcagag cggcggacat cggcacgcgg ccgtcgcgga cggcgccggc gacttgattc
    16321 gaggcgacga gagagtcgct cacggtgatt tgaacgcggc cgtcggtggc ttcgtcgatt
    16381 cgctctggaa tgccctgggt gagtgcggtg tagacgtcac cgggcgacac gatgacagcc
    16441 atcgtgaagt cgaattctgg ttcctgtgca acggcttggc cagccgtgag ggacaggccc
    16501 agggccgctg cgcccatcac gccgcgcgcc gtggatttaa gtgaaatggt cattgagttc
    16561 ctcccaaaaa gtggaatttc gccgcgatcg aaaggatccg gaatcgtgcg atcgtggtag
    16621 gagcatacga taatacaaaa tgttgcttgt caaccttcgc cctgatacgg ttcaagccaa
    16681 gggagcggcg tgggagcgcg tcgacggcta cggaggatga ggaatctcat gagcaacgac
    16741 actacgctga gcgtcccgca ggggggctcc gacggtaacc tgttcattgc gtcggttcgg
    16801 ggtctgacac agcttgcagg tcttctggcg gcgatgacgc ttctgttcat gacgctgatc
    16861 gttttttacg aggtcgtcat gcggtcggtg ttcaacgcgc cgaccagctg ggtcgccgag
    16921 atcagcgtgt attcctttgt tgccatggtg tttttcggga tgggcgtggc ccagacgaag
    16981 ggcgcgcata tccgggtgga agtgctgctc gattccgtca aggacgagac ccgcacgctg
    17041 ctgatgctgc tgggggactg gctgctgctg gtgctggtgg cgctgagcgg ctgggagatg
    17101 ttctgtttca cggtgtcgga attcatcaac ggcacgcgcg actgggggct tctggcgacg
    17161 ccgcagtgga ttcccgaaac gcctgtcgtg atcggttatg cgctgttctt cttctcgatt
    17221 ctacagacgg cgttcgatga gcgcgccccg aagaccgagg cgcggatctg ggcggcgccg
    17281 gcgatcgtgc tggcggcgat cggggcgctt gcgctgatcg ggcggcggga ctggttcccg
    17341 ttcgactggc tgccggtgga tatggcgacg ctggtcatca cggccgcgat cctgctgatt
    17401 gccgccctgt ggagcggggc gcggattgcc ggcatccttc tcgggctgct ggtggtgatg
    17461 gcggtgctct tttcctatgc gcaggacgcc tcgcttgtgt tcaccggcgt gctgatgacg
    17521 gtctcgctgc ttggccttct gctgcttggg gttccggtcg gtggcacgct tgggatggtc
    17581 gggctgatgg ggctggcctt cacgctgaac aacccgcagc tgccgatcct ggcggaccgg
    17641 tcctggacga gcatcaactc gttcacgctg accgccgtgc cggccttcgt gctgatgggc
    17701 acgctgctgg tgcatagcgg ggtcacggtg cggctgttcg acatgctggt ctgctggttc
    17761 gggcgggcgc gcggcgggct gggccatgcc gcgatcgggt cgtcggcgat cttcgcggcg
    17821 gtgtcggggt cgagcctggc gacggcggcg acgctgggcc gggtggccgc gccggagctc
    17881 aattcacgcg gttacagccg gcgcctgacc tatggtgtgg tcgcggccgg ctcgacgctg
    17941 ggtatccttg tgccgccgag catcgcgatg atcatctacg gcaacacggt cggcgcgccg
    18001 atcaccgtgc tgttcgttgc gggcgttgtg cccggtctgg tgctggcctg tcttttcgcg
    18061 ctgaccatct tgatctggtc ctacctgtcg aaagaggcgg tgccggaggg cgagcggtat
    18121 tccatgggcg agaagttccg gtcgacgctg ggcgttctgc cgttcctcgt gctgatcgcg
    18181 gcggtgctgg ggtcgctcta tttcgggatc gccacgccca cggaagccgg ggctgtcggg
    18241 gcggtcgccg cctttgcgat ctgtgttgcg gccgggcggg ccgcgccgat ggatatctat
    18301 cacgcgctga ccgacacggt gaaagtgacc gccttcatca tgctgatcgt ggtgggcgcg
    18361 tcgatctttt cctgggtgtt cgatttcctg cggctgccgc gcgagctggt cagcacggtg
    18421 acggaggccg agttgcagcc gtggctggtg atgctgctgc tggcggtgtt ctacctgctg
    18481 atgggcacgc tgatcgagtc gatctcgatg atgctgatga cgctgtcggt gaccttcccg
    18541 atcgtcgtgg cgctgggctt cgacccgatc tggttcggcg tggtgctggt gctgctggtc
    18601 gagatcggcc tgatcacacc accggtcggc atcgtgctgt ttatcctgcg agggctggga
    18661 gacgtgtcgc tcagggatat tacgctgggc gtcattccct tcatcctggt gatgctgtcg
    18721 atgctggtgc tgctctactt cttccctgac atcgtgctct ggctgccaga gcagatggaa
    18781 ggctgacatt aaaataacca ctaccaagga gttatcggaa tgagcctcaa gcttggcttt
    18841 gtcggaatcg gtcgtatggg caaacccatg gccggacatc tactggacgc gggctatgac
    18901 ctgaccgtgt tcgacccgaa caaatcggcc gtcgaggcgc tggtcgccaa gggggccaag
    18961 gccgcggaaa gccccaaggc cgtgggcgac gaagcggaac tgatcctgat gtcgctgccg
    19021 acgccggatg tcgtgaccga ggccgcgacc ggggccgagg ggatttcgaa agggtcgaag
    19081 gcgcgggcgg tgatcgacct gtcgacgacc ggcccgaccg cggcaagggc gctggcagag
    19141 gggctgaagg ccgacgggct tggctgtgtc gactcgccgg tgagcggcgg tgtggccggg
    19201 gccgagaagg gcagcctgac gctgatgacg gcctgtaccg acgagctttt cgccgaggtc
    19261 gagccgatcc tgaagctctt tggcaaggtg acccatgtgg ggcaggaagc cgggcaggcg
    19321 cagctgatca aggtgatcaa caacctgatg tcggtgacgg cgctggcgat tgcgtcggaa
    19381 ggtatcgtgc tggccgaaaa ggcgggcgtt tcgggtgaga cgctgatgaa cgtggtcaac
    19441 cagggcagcg ggcggtcgaa tgccagcgaa gacaagatcc cgaaatacgt gctgagccgg
    19501 aaattcgatt tcggctttgc gctggggctg tcggcgaagg acgttcggct gtgcatcgcg
    19561 gaaagcgagg cgcttggcgt gccgatgatc gtgggcagcg cggcgaagat gctgatgggc
    19621 atcgcgcata cgcagcaggg gcccgacgcg gacctgaccg agctgatcaa gtcggtcgag
    19681 cggctggcca acgtggagca ggcctcttga ccgaggtcac ccgggcgctt gcagagtttg
    19741 ccgcgacggc cgaggtgccc gagcctgttc gggaggaagc caagcgctcg atcctgaacg
    19801 ggctggccac cgggattgcc ggtgcggagg atgacgcggt gcgcatcgcg caggcgacgc
    19861 tcgaccggct ggagccgggc cagggcgtgg gcctgattgc gcgcgaccag gaggcggggc
    19921 cgctgacggc ggccttcctg aacgcgatgg cgatcaacgt gcatgatttc gatgacacgc
    19981 atcccggcac gattctgcat tcgacggcgc cggtgctgcc ggtgctgctg tcgctggcgg
    20041 cgcagcagac ggtgagcggg cgggcgtttc tggaggccta tgcggtgggc gtcgaggtgg
    20101 aatgccgggt cgccaacgcg gtgtcgccgg ggcattaccg gcggggctgg catatcaccg
    20161 gcacctgcgg ggtgttcggg gcggcggccg cggcggggcg tatcctcggg ctgacggccg
    20221 ggcagatggt ggatgcgttc gggtcggcct cggcgcaatc gtcggggctg gtggaaacgc
    20281 tgggctacat ggcgaaaagc gtgggtgtcg gcggggccgc gcgcggcggg ctgctggcgg
    20341 cctggctggc gaaggacggg ctttcgggcc cggcggcgcc gctggaaggg ccgcgggggt
    20401 ttctgcgggt gacgtctgat gcgccggatt tcgagcaggc gatgccgctc attggtggca
    20461 agtgggaact gatgcggatc acctataagc cttacccctg tggcgtggtg ctgaacccgg
    20521 tgatcgaggc ggcgctgacg ctgggcgggg gcaagagcca cgcgccgggc gagattgcgt
    20581 cggtgacggt gacggggcac ccgctgctgg ccgagcgggc cgaccggccc tcgccggaaa
    20641 gcgggcggac ggcgcaggtg agtgcgcagc atgcggttgc ggcctgtttt ggccgggcgg
    20701 cggccgggtt gccggagttt tccgacgcgg ccgtggcgga tgcggcgctg acagagctgc
    20761 gggcgaaggt cgtggtggtg caggacgaga gctatccggt gggcgcggcc cgcgtggacg
    20821 tggcgctggc ggatggcggg acgcgcacgg agacggtgga cgtggccgag ggcgacctcg
    20881 ggcggccgct gtcgacggag cggttgcagc agaagctggc ggaccttgtg gcgctgggcg
    20941 ggtcggggtg cgacccggtg gcgattgccg aggcggtgct ggggcttgac cgggccgacg
    21001 atgccgcgcc gatcttgcgg ctcgtccgcc cgggctgagc gtgttcaggt ggcgggcgcg
    21061 cgatcgcccg ccgtcacacc gccgtcgatg gtgaaggcct gtccgttgac catcgcggat
    21121 tcctcggcgc agagatagac ggccatctgg gccacctcgt cggcggtgat catccggccg
    21181 gtgggctggt atttcgagag cgcctcgaac cgttcttcga cctcgtcggg gtagtattcc
    21241 gtgaggtagg agcggatgaa gggtgtctcg acccgggccg cgcagatgca gttggcgcgg
    21301 atgccttttg ccacgtaatc gacggcgacc gagcgggtca tcatcacgat ggccgccttg
    21361 gaggcgccgt aggcgaagcg ttcgtacatg gcgtgcaccc cggcgagcga ggccatgttg
    21421 aggatggtgc cgccgccgcg ggcgatcatg ccgggcatga atccctgcat catcatcatc
    21481 gtgccgcgca tgttcacccg gtagacgaga tcgagatcct cgggcgaggc gtcgagcagg
    21541 gcgccgatgc ggatggcggc ggcgttgttg acgagcacgt tgatggggag gttttcggcc
    21601 tcgaggctgt cgttgagcgc cgcgatggcg gtggggtcgg tgatgtcgag cgcgcgcagg
    21661 tggagggtgt cggtcttcgc gtccgcgaac ttggtttcga gggcggcgag gtcgagatcg
    21721 gtggcgatga cctgcgcgcc ctgcgagagg aagagcttgg tcagggccga tccgataccg
    21781 ccggcggcgc cggtcacgag gcatgtcttg ccgttcagtc gcatggaatg gtctcctttc
    21841 acgccacgga ccagccgccg tcgatcggca ggtcggcccc gttgatgtct gcggccgcat
    21901 cgctgcacag gaaggtggcg gcggcgccga cggccgcgag gtcgacgaag cggccgttgg
    21961 ggttgcgggt ggcgaggtag gtctgcttcg cctcgtccag agtgatgccg gcgtcgcgcg
    22021 cctgtccggc gatgcggtcc tcgatcggtt cggagaggac ggtgccgggg gagatggcgt
    22081 tgcaggtgat gccggtctgg gccagttcca gcgcgagggc gcgggtcatg ccgataagtc
    22141 cggccttggt ggtgacgtag tcgatgcggt tggcggcgcc cttggtgccg tagatcgacg
    22201 cgacgttgag aatgcggccc cagcc
//
