LOCUS       NZ_VYTZ01000033         8331 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold33, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000033
VERSION     NZ_VYTZ01000033.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 8331)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 8331)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 0
            Orig. end                         :: 8331
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000033.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     cand_cluster    1..8331
                     /SMILES="C=CC(C)C(=O)C(=O)O"
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(PKS_AT and (PKS_KS or ene_KS or
                     mod_KS or hyb_KS or itr_KS or tra_KS))"
                     /kind="single"
                     /product="T1PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..8331
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[861:>8331](-)"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(862..>8331)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS
                     or hyb_KS or itr_KS or tra_KS))"
                     /neighbourhood="20000"
                     /product="T1PKS"
                     /protocluster_number="1"
     aSDomain        complement(<1..750)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36630_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="3.50E-104"
                     /label="F5972_RS36630_PKS_KS.1"
                     /locus_tag="F5972_RS36630"
                     /protein_end="285"
                     /protein_start="35"
                     /score="341.0"
                     /tool="antismash"
                     /translation="IAIVGMGCRLPGGVTSPEDLWDLVAEGRDAVTEFPTDRGWDLDAL
                     YDPDPDQPHTSYTRHGGFLDDIAGFDAAFFGISRREALASDPQQRLLLEVAWETLERAG
                     IDPATLKGSRTAVYAGVADRTYGSRLPEVPEDLEGYLAIGNLGSVLSGRIAYTFGFEGP
                     AVTVDTACSSSLVALHLAVQALRTGECDLALAGGVTVMASPIGFTEFSRQRGLAPDGRC
                     KAFSSTADGTGWAEGVGLLLVERLSDAQ"
     gene            complement(<1..855)
                     /locus_tag="F5972_RS36630"
                     /old_locus_tag="F5972_36635"
     CDS             complement(<1..855)
                     /NRPS_PKS="Domain: PKS_Docking_Nterm (3-31). E-value:
                     3.2e-10. Score: 31.4. Matches aSDomain:
                     nrpspksdomains_F5972_RS36630_PKS_Docking_Nterm.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (35-285). E-value:
                     3.5e-104. Score: 341.0. Matches aSDomain:
                     nrpspksdomains_F5972_RS36630_PKS_KS.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) mod_KS"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1022: Beta-ketoacyl synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019606713.1"
                     /locus_tag="F5972_RS36630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_36635"
                     /product="beta-ketoacyl synthase N-terminal-like
                     domain-containing protein"
                     /protein_id="WP_191910504.1"
                     /sec_met_domain="mod_KS (E-value: 6.5e-131, bitscore:
                     424.1, seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 2e-97, bitscore:
                     312.7, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANDDKLREYLKRSIAETKQAEKRLRQIEAKSREPIAIVGMGCRL
                     PGGVTSPEDLWDLVAEGRDAVTEFPTDRGWDLDALYDPDPDQPHTSYTRHGGFLDDIAG
                     FDAAFFGISRREALASDPQQRLLLEVAWETLERAGIDPATLKGSRTAVYAGVADRTYGS
                     RLPEVPEDLEGYLAIGNLGSVLSGRIAYTFGFEGPAVTVDTACSSSLVALHLAVQALRT
                     GECDLALAGGVTVMASPIGFTEFSRQRGLAPDGRCKAFSSTADGTGWAEGVGLLLVERL
                     SDAQ"
     source          1..8331
                     /collection_date="2015-04-30"
                     /db_xref="taxon:2614688"
                     /geo_loc_name="China: Heilongjiang Province, Heihe City"
                     /isolation_source="soil"
                     /mol_type="genomic DNA"
                     /organism="Microbispora cellulosiformans"
                     /strain="Gxj-6"
                     /submitter_seqid="Scaffold33"
                     /type_material="type strain of Microbispora
                     cellulosiformans"
     region          1..8331
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T1PKS"
                     /region_number="1"
                     /rules="cds(PKS_AT and (PKS_KS or ene_KS or mod_KS or
                     hyb_KS or itr_KS or tra_KS))"
                     /tool="antismash"
     CDS_motif       complement(220..267)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36630_0002"
                     /evalue="9.60E-08"
                     /label="PKSI-KS_m3"
                     /locus_tag="F5972_RS36630"
                     /protein_end="212"
                     /protein_start="196"
                     /score="23.6"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     CDS_motif       complement(469..495)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36630_0001"
                     /evalue="2.90E-03"
                     /label="PKSI-KS_m2"
                     /locus_tag="F5972_RS36630"
                     /protein_end="129"
                     /protein_start="120"
                     /score="10.3"
                     /tool="antismash"
                     /translation="DPQQRLLLE"
     aSDomain        complement(763..846)
                     /aSDomain="PKS_Docking_Nterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36630_PKS_Docking_Nterm.
                     1"
                     /evalue="3.20E-10"
                     /label="F5972_RS36630_PKS_Docking_Nterm.1"
                     /locus_tag="F5972_RS36630"
                     /protein_end="31"
                     /protein_start="3"
                     /score="31.4"
                     /tool="antismash"
                     /translation="DDKLREYLKRSIAETKQAEKRLRQIEAK"
     gene            complement(862..>8331)
                     /locus_tag="F5972_RS36635"
                     /old_locus_tag="F5972_36640"
     CDS             complement(862..>8331)
                     /NRPS_PKS="Domain: PKS_AT (144-453). E-value: 1.6e-104.
                     Score: 341.4. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_AT.1"
                     /NRPS_PKS="Domain: PKS_DH (518-677). E-value: 3.6e-58.
                     Score: 188.5. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_DH.1"
                     /NRPS_PKS="Domain: PKS_KR (1034-1215). E-value: 3.6e-54.
                     Score: 175.4. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_KR.1"
                     /NRPS_PKS="Domain: PKS_PP (1302-1386). E-value: 2.3e-27.
                     Score: 87.2. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_PP.1"
                     /NRPS_PKS="Domain: PKS_KS(Modular-KS) (1413-1838). E-value:
                     5.4e-185. Score: 607.2. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_KS.1"
                     /NRPS_PKS="Domain: PKS_AT (1947-2245). E-value: 5.6e-109.
                     Score: 356.0. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_AT.2"
                     /NRPS_PKS="Domain: PKS_PP (2326-2409). E-value: 1.2e-29.
                     Score: 94.4. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_PP.2"
                     /NRPS_PKS="Domain: PKS_Docking_Cterm (2426-2488). E-value:
                     6.3e-09. Score: 28.6. Matches aSDomain:
                     nrpspksdomains_F5972_RS36635_PKS_Docking_Cterm.1"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     mod_KS"
                     /gene_functions="biosynthetic (rule-based-clusters) T1PKS:
                     PKS_AT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ketoacyl-synt"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012901.5"
                     /locus_tag="F5972_RS36635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_36640"
                     /product="type I polyketide synthase"
                     /protein_id="WP_150940735.1"
                     /sec_met_domain="adh_short (E-value: 5.4e-56, bitscore:
                     176.4, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="mod_KS (E-value: 2e-235, bitscore: 768.4,
                     seeds: 217, tool: rule-based-clusters)"
                     /sec_met_domain="ketoacyl-synt (E-value: 9.3e-97, bitscore:
                     310.6, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="PKS_AT (E-value: 1.9e-110, bitscore:
                     356.0, seeds: 1682, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-16, bitscore:
                     47.9, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="GNLQLLTHPQPWPDHARPRRAAVSAFGVSGTNAHVIIEQAPDQAE
                     LESPQARPSPAVGWVVSARSPEALRAQAARLADHLDRHPTLGAADVAHSLATTRARFDH
                     RAVITGTTRQELLDRTRALADGTSAGGIVTGIARPAKVAFVYTGQGSQRPGMGRGLHAA
                     HPAFATAYDQAINLLDQHLARHTPVPLREVLLGDADPALLDQTLYTQPALFALQTALTH
                     LLTRWGITPHAVAGHSIGAIAAAHTAGILTLPDAAALVAARARLMHTAPPGGAMTAINA
                     TEAHITREIAAYKGRVTIAAANTPTSTVISGDHDPVTHLTEHFRQQGHKVRALTVSHAF
                     HSPHMDPILDEFEQAVAALSLTPPTGPVTPFVSDLTGTTATPTDLTNPAYWARHLRNPV
                     RFADVVQRLHEGPEPGEGVRTFLEIGPDGILTGLIRETLDSEQGILAVPVLRRDRPEPP
                     TALTAAAHAHTHGTPVDWATVNGPATTVDLPTYAFQHERLWLTPPPRQTDPANLGLTTT
                     AHPLLGAALTLAHHDTTVYTGTLSLTTHPWLTDHTVFDTPILPGTAYLDLALHAADHTG
                     HTTIDELVLHAPLALPESGGVQVQIIVTGSDRPSLEIFSRPEGDTGDWTRHATAVLARD
                     DTEPGFDLTAWPPEDAVQVDLGTAYDRLYEAGLGYGPAFRGLRAAWRRGDELFAEVALP
                     EDERDDVTDYGIHPALLDAALHGAALHWLDGTPNGHSNLPFAWSGVRLHATGATDLRVR
                     VTLGDAGSLSLHVADPTGAPVATIDTLTTRLVSSEQLVTSGSTPDSSLFRVEWSPLELQ
                     PAADEAWAVLGDRELHDTLRRTVTTSYYDDLTALTDAIDAAEPAPDVIVLPITPHHATG
                     NGNARNGTTGADNAAHVEPEQATHATGSNSRTGENPVAAAHAVAEHTLAALQTFLADDR
                     LSGTRLLVLTHNAVATTSQQPIDLVTAPVWGLIRSAQTEHPGRIHLIDHHHETAGLLPQ
                     AAATACHHDEPHTALRDGTLLTPRLIAHTTQHKAEEVQPRGWDPDGTVLITGGLTGIGA
                     LLARHLATTHGIRHLHLTGRRGHHTPGADTLIRDLTTAGAHVTVTAADITDPHAVEALI
                     ASIPADHPLTAVIHAAGITHDTPLHTLTPNHHLHPVLAPKIDGATHLHHHTRHHNPAAF
                     ILFSSISGLLGGAAQANYAAANTFHDALAHHRHTQRLPATSLAWGLWAHTSTLTAGLGQ
                     NDHRRLARLGLRPLETDHALALFDAVVFGAAAQPPVLVPARLNTTTDAPPPLLRRLISP
                     RRRAVRAAAGQDGSLATRLAALTAERRSAALLDLVRTEVATVLSHPHPHTIPPDRPLIE
                     LGLDSLTAVELRNRLTTTTTLRLPATLTFDHPTPQGIADLLDGLLGGGGRAEKAPVRAE
                     TTATGSLADDPIVIVGMACRLPGGIESPEALWRLVERGGDAVSEFPADRGWDLERLYDP
                     DPDHLGTSYTRHGGFLRDVADFDAAFFGISPREALATDPQQRLLLEVAWEAFERAGIDP
                     RRLRGSRTGVFAGVMYHDYAPRLQEIPGDLEGYLVNGSAGSIASGRVAYTFGFEGPAVT
                     VDTACSSSLVALHLAAQSLRTGESDLALAGGVAVMSSPATFVEFSRQRALAVDGRCKAF
                     SSSADGTGWGEGVALLLLERLSDARRNNHPVLAVVRGSAVNQDGASNGLTAPSGPSQQR
                     VIRQALANAGLTTGEVDVVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSLKSN
                     IAHTQAAAGGAGVIKMIMAMRAGVLPKTLHVEEPSPHVDWSSGGVRLLDEARPWPEDGG
                     PRRAGVSSFGVSGTNAHVILEQPPAAEEPVGTPATPPAVPPAVPWVLSGHLPEALRGQA
                     VSLATYLDGRADLDPVDVAHSLVSARTLLGERAVVVAPDTAGLTSGLAALTREGALPGH
                     VVRGTADVAGKVVFVFPGQGGQWPGMAAGLLETAPVFAERLAECERALSEFVDWSLLDV
                     VRGVPGAPGLDRVDVVQPVLWAVMVSLAGLWQSYGVRPDAVVGHSQGEIAAAVVAGGLS
                     LRDAARVVALRSQAIRTLSGDGGMASVALPLEEAEARIAPWDGRLSVGVVNGPGSVVVS
                     GEVSALGELLAALDAEGVRNRRLPVDYASHSAQVELISDELLKALSPITPRALTVPMLS
                     TVSGEWAGEAELDAEYWYANLRRPVRFEAATRALAASGHTAFVEISPHPVLASSIEDTL
                     DAAAVAPALVTGTLRRDEGGPERFLVSLAEAFVRGVPVDWAVALRGADPRRVDLPTYAF
                     QRTRFWLDASRTSSATSSAGGAADDGAAGGRAPEPASRFAGLDPEQRREAVLGLVRTEV
                     AAVLRHADGEEIPPARAFRELGLDSLTAVDLRNRLRTATGLPLPTTLIFDHPSPAAVTD
                     YILSALAEAEADRDGEPAGDPLTALRRLEASLLAEPGGRGEVVSRLRALLARFDAPLGA
                     DDDTGDEIDLDSATDDELFDLLDRG"
     aSDomain        complement(865..1050)
                     /aSDomain="PKS_Docking_Cterm"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_Docking_Cterm.
                     1"
                     /evalue="6.30E-09"
                     /label="F5972_RS36635_PKS_Docking_Cterm.1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2488"
                     /protein_start="2426"
                     /score="28.6"
                     /tool="antismash"
                     /translation="LTALRRLEASLLAEPGGRGEVVSRLRALLARFDAPLGADDDTGDE
                     IDLDSATDDELFDLLDR"
     aSDomain        complement(1102..1350)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_PP.2"
                     /evalue="1.20E-29"
                     /label="F5972_RS36635_PKS_PP.2"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2409"
                     /protein_start="2326"
                     /score="94.4"
                     /tool="antismash"
                     /translation="AGLDPEQRREAVLGLVRTEVAAVLRHADGEEIPPARAFRELGLDS
                     LTAVDLRNRLRTATGLPLPTTLIFDHPSPAAVTDYILS"
     aSModule        complement(1102..4089)
                     /complete
                     /domains="nrpspksdomains_F5972_RS36635_PKS_KS.1"
                     /domains="nrpspksdomains_F5972_RS36635_PKS_AT.2"
                     /domains="nrpspksdomains_F5972_RS36635_PKS_PP.2"
                     /locus_tags="F5972_RS36635"
                     /monomer_pairings="mmal -> Me-mal"
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(1594..2487)
                     /ASF="Methylmalonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: True"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_AT.2"
                     /evalue="5.60E-109"
                     /label="F5972_RS36635_PKS_AT.2"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2245"
                     /protein_start="1947"
                     /score="356.0"
                     /specificity="substrate consensus: mmal"
                     /specificity="PKS signature: Methylmalonyl-CoA"
                     /specificity="Minowa: mmal"
                     /tool="antismash"
                     /translation="VFPGQGGQWPGMAAGLLETAPVFAERLAECERALSEFVDWSLLDV
                     VRGVPGAPGLDRVDVVQPVLWAVMVSLAGLWQSYGVRPDAVVGHSQGEIAAAVVAGGLS
                     LRDAARVVALRSQAIRTLSGDGGMASVALPLEEAEARIAPWDGRLSVGVVNGPGSVVVS
                     GEVSALGELLAALDAEGVRNRRLPVDYASHSAQVELISDELLKALSPITPRALTVPMLS
                     TVSGEWAGEAELDAEYWYANLRRPVRFEAATRALAASGHTAFVEISPHPVLASSIEDTL
                     DAAAVAPALVTGTLRRD"
     CDS_motif       complement(1669..1698)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0019"
                     /evalue="7.20E-03"
                     /label="PKSI-AT-mM_m9"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2220"
                     /protein_start="2210"
                     /score="9.2"
                     /tool="antismash"
                     /translation="FVEISPHPVL"
     CDS_motif       complement(1741..1788)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0018"
                     /evalue="1.40E-05"
                     /label="PKSI-AT-mM_m8"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2196"
                     /protein_start="2180"
                     /score="17.1"
                     /tool="antismash"
                     /translation="LDAEYWYANLRRPVRF"
     CDS_motif       complement(1894..1926)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0017"
                     /evalue="6.70E-04"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2145"
                     /protein_start="2134"
                     /score="12.4"
                     /tool="antismash"
                     /translation="VDYASHSAQVE"
     CDS_motif       complement(1993..2031)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0016"
                     /evalue="4.90E-02"
                     /label="PKSI-AT-mM_m5"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2112"
                     /protein_start="2099"
                     /score="6.7"
                     /tool="antismash"
                     /translation="VVNGPGSVVVSGE"
     CDS_motif       complement(2140..2250)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0015"
                     /evalue="2.80E-18"
                     /label="PKSI-AT-mM_m3"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2063"
                     /protein_start="2026"
                     /score="57.7"
                     /tool="antismash"
                     /translation="GVRPDAVVGHSQGEIAAAVVAGGLSLRDAARVVALRS"
     CDS_motif       complement(2254..2325)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0014"
                     /evalue="5.90E-10"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="F5972_RS36635"
                     /protein_end="2025"
                     /protein_start="2001"
                     /score="31.2"
                     /tool="antismash"
                     /translation="LDRVDVVQPVLWAVMVSLAGLWQS"
     CDS_motif       complement(2437..2493)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0013"
                     /evalue="6.50E-08"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1964"
                     /protein_start="1945"
                     /score="24.5"
                     /tool="antismash"
                     /translation="VFVFPGQGGQWPGMAAGLL"
     aSDomain        complement(2815..4089)
                     /ASF="found active site cysteine: True, scaffold matched
                     GSSS: True"
                     /ASF="found active site histidines: True"
                     /aSDomain="PKS_KS"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_KS.1"
                     /domain_subtypes="Modular-KS"
                     /evalue="5.40E-185"
                     /label="F5972_RS36635_PKS_KS.1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1838"
                     /protein_start="1413"
                     /score="607.2"
                     /tool="antismash"
                     /translation="IVIVGMACRLPGGIESPEALWRLVERGGDAVSEFPADRGWDLERL
                     YDPDPDHLGTSYTRHGGFLRDVADFDAAFFGISPREALATDPQQRLLLEVAWEAFERAG
                     IDPRRLRGSRTGVFAGVMYHDYAPRLQEIPGDLEGYLVNGSAGSIASGRVAYTFGFEGP
                     AVTVDTACSSSLVALHLAAQSLRTGESDLALAGGVAVMSSPATFVEFSRQRALAVDGRC
                     KAFSSSADGTGWGEGVALLLLERLSDARRNNHPVLAVVRGSAVNQDGASNGLTAPSGPS
                     QQRVIRQALANAGLTTGEVDVVEAHGTGTTLGDPIEAQALLATYGQDRPADRPLWLGSL
                     KSNIAHTQAAAGGAGVIKMIMAMRAGVLPKTLHVEEPSPHVDWSSGGVRLLDEARPWPE
                     DGGPRRAGVSSFGVSGTNAHVILEQP"
     CDS_motif       complement(3139..3183)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0012"
                     /evalue="5.80E-04"
                     /label="PKSI-KS_m5"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1730"
                     /protein_start="1715"
                     /score="12.2"
                     /tool="antismash"
                     /translation="VEAHGTGTTLGDPIE"
     CDS_motif       complement(3559..3606)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0011"
                     /evalue="1.30E-06"
                     /label="PKSI-KS_m3"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1590"
                     /protein_start="1574"
                     /score="20.3"
                     /tool="antismash"
                     /translation="GPAVTVDTACSSSLVA"
     aSDomain        complement(4171..4422)
                     /aSDomain="PKS_PP"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_PP.1"
                     /evalue="2.30E-27"
                     /label="F5972_RS36635_PKS_PP.1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1386"
                     /protein_start="1302"
                     /score="87.2"
                     /tool="antismash"
                     /translation="LAALTAERRSAALLDLVRTEVATVLSHPHPHTIPPDRPLIELGLD
                     SLTAVELRNRLTTTTTLRLPATLTFDHPTPQGIADLLDG"
     aSModule        complement(4171..7896)
                     /complete
                     /domains="nrpspksdomains_F5972_RS36635_PKS_AT.1"
                     /domains="nrpspksdomains_F5972_RS36635_PKS_DH.1"
                     /domains="nrpspksdomains_F5972_RS36635_PKS_KR.1"
                     /domains="nrpspksdomains_F5972_RS36635_PKS_PP.1"
                     /locus_tags="F5972_RS36635"
                     /monomer_pairings="mal -> ccmal"
                     /starter_module
                     /tool="antismash"
                     /type="pks"
     aSDomain        complement(4684..5226)
                     /ASF="KR domain putatively catalyzing D-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_KR.1"
                     /evalue="3.60E-54"
                     /label="F5972_RS36635_PKS_KR.1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1215"
                     /protein_start="1034"
                     /score="175.4"
                     /specificity="KR activity: active"
                     /specificity="KR stereochemistry: (unknown)"
                     /tool="antismash"
                     /translation="GTVLITGGLTGIGALLARHLATTHGIRHLHLTGRRGHHTPGADTL
                     IRDLTTAGAHVTVTAADITDPHAVEALIASIPADHPLTAVIHAAGITHDTPLHTLTPNH
                     HLHPVLAPKIDGATHLHHHTRHHNPAAFILFSSISGLLGGAAQANYAAANTFHDALAHH
                     RHTQRLPATSLAWGLWAH"
     CDS_motif       complement(4732..4833)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0010"
                     /evalue="1.50E-18"
                     /label="PKSI-KR_m4"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1199"
                     /protein_start="1165"
                     /score="59.3"
                     /tool="antismash"
                     /translation="FILFSSISGLLGGAAQANYAAANTFHDALAHHRH"
     CDS_motif       complement(5122..5223)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0009"
                     /evalue="3.30E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="1069"
                     /protein_start="1035"
                     /score="23.0"
                     /tool="antismash"
                     /translation="TVLITGGLTGIGALLARHLATTHGIRHLHLTGRR"
     aSDomain        complement(6298..6774)
                     /ASF="catalytic triad H,G,P found: False"
                     /aSDomain="PKS_DH"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_DH.1"
                     /evalue="3.60E-58"
                     /label="F5972_RS36635_PKS_DH.1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="677"
                     /protein_start="518"
                     /score="188.5"
                     /tool="antismash"
                     /translation="HPLLGAALTLAHHDTTVYTGTLSLTTHPWLTDHTVFDTPILPGTA
                     YLDLALHAADHTGHTTIDELVLHAPLALPESGGVQVQIIVTGSDRPSLEIFSRPEGDTG
                     DWTRHATAVLARDDTEPGFDLTAWPPEDAVQVDLGTAYDRLYEAGLGYGPAFRGL"
     CDS_motif       complement(6613..6690)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0008"
                     /evalue="7.80E-10"
                     /label="PKSI-DH_m2"
                     /locus_tag="F5972_RS36635"
                     /protein_end="572"
                     /protein_start="546"
                     /score="31.2"
                     /tool="antismash"
                     /translation="WLTDHTVFDTPILPGTAYLDLALHAA"
     CDS_motif       complement(6871..6900)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0007"
                     /evalue="1.90E+00"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="F5972_RS36635"
                     /protein_end="486"
                     /protein_start="476"
                     /score="2.4"
                     /tool="antismash"
                     /translation="ATVNGPATTV"
     aSDomain        complement(6970..7896)
                     /ASF="Malonyl-CoA specific"
                     /ASF="found active site serine: True, scaffold matched
                     GHGE: False"
                     /aSDomain="PKS_AT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS36635_PKS_AT.1"
                     /evalue="1.60E-104"
                     /label="F5972_RS36635_PKS_AT.1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="453"
                     /protein_start="144"
                     /score="341.4"
                     /specificity="substrate consensus: mal"
                     /specificity="PKS signature: Malonyl-CoA"
                     /specificity="Minowa: mal"
                     /tool="antismash"
                     /translation="VYTGQGSQRPGMGRGLHAAHPAFATAYDQAINLLDQHLARHTPVP
                     LREVLLGDADPALLDQTLYTQPALFALQTALTHLLTRWGITPHAVAGHSIGAIAAAHTA
                     GILTLPDAAALVAARARLMHTAPPGGAMTAINATEAHITREIAAYKGRVTIAAANTPTS
                     TVISGDHDPVTHLTEHFRQQGHKVRALTVSHAFHSPHMDPILDEFEQAVAALSLTPPTG
                     PVTPFVSDLTGTTATPTDLTNPAYWARHLRNPVRFADVVQRLHEGPEPGEGVRTFLEIG
                     PDGILTGLIRETLDSEQGILAVPVLRRD"
     misc_feature    complement(6982..6984)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     CDS_motif       complement(7126..7161)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0006"
                     /evalue="1.50E-05"
                     /label="PKSI-AT-M_m8"
                     /locus_tag="F5972_RS36635"
                     /protein_end="401"
                     /protein_start="389"
                     /score="18.2"
                     /tool="antismash"
                     /translation="YWARHLRNPVRF"
     CDS_motif       complement(7291..7317)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0005"
                     /evalue="9.90E+00"
                     /label="PKSI-AT-mM_m6"
                     /locus_tag="F5972_RS36635"
                     /protein_end="346"
                     /protein_start="337"
                     /score="0.3"
                     /tool="antismash"
                     /translation="HAFHSPHMD"
     CDS_motif       complement(7393..7431)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0004"
                     /evalue="3.20E-02"
                     /label="PKSI-AT-M_m5"
                     /locus_tag="F5972_RS36635"
                     /protein_end="312"
                     /protein_start="299"
                     /score="7.8"
                     /tool="antismash"
                     /translation="AAANTPTSTVISG"
     CDS_motif       complement(7525..7647)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0003"
                     /evalue="2.20E-18"
                     /label="PKSI-AT-M_m3"
                     /locus_tag="F5972_RS36635"
                     /protein_end="268"
                     /protein_start="227"
                     /score="58.4"
                     /tool="antismash"
                     /translation="GITPHAVAGHSIGAIAAAHTAGILTLPDAAALVAARARLMH"
     CDS_motif       complement(7660..7707)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0002"
                     /evalue="4.40E-02"
                     /label="PKSI-AT-mM_m2"
                     /locus_tag="F5972_RS36635"
                     /protein_end="223"
                     /protein_start="207"
                     /score="7.4"
                     /tool="antismash"
                     /translation="YTQPALFALQTALTHL"
     CDS_motif       complement(7849..7899)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS36635_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-AT-mM_m1"
                     /locus_tag="F5972_RS36635"
                     /protein_end="160"
                     /protein_start="143"
                     /score="17.2"
                     /tool="antismash"
                     /translation="FVYTGQGSQRPGMGRGL"
ORIGIN
        1 ttgggcgtcg gagaggcgtt cgaccaggag gaggccgacg ccttcggccc agccggtgcc
       61 gtcggcggtg gaggagaacg ccttgcagcg tccgtccggc gcgagccccc gctgccgcga
      121 gaactcggtg aacccgatcg ggctcgccat caccgtcacc ccgcccgcga gcgcgagatc
      181 gcattccccc gtacgcagag cctggacggc caggtgcagg gcgaccagcg acgacgagca
      241 ggccgtgtcg acggtcaccg ccgggccctc gaagccgaag gtgtaggcga tccgccccga
      301 cagcacgctg cccaggttgc cgatcgctag atagccctcc aggtcctcgg gcacctccgg
      361 cagccgtgac ccgtatgtac ggtcggccac ccccgcgtac accgccgtac ggctgccctt
      421 gagggtggcg gggtcgatgc cggcgcgttc gagggtttcc caggcgactt cgaggaggag
      481 gcgttgctgg gggtcgctgg cgagggcttc gcggcgggag atgccgaaga aggcggcgtc
      541 gaatccggcg atgtcgtcga ggaagccgcc gtggcgggtg taggaggtgt ggggctggtc
      601 ggggtcgggg tcgtagagcg cgtcgaggtc ccagccgcgg tcggtgggaa actcggtgac
      661 ggcgtcgcgg ccctcggcga ccaggtccca caggtcctcg ggggaggtca ccccgccggg
      721 caggcggcag cccatcccca cgatcgcgat cggctcccgc gacttcgcct cgatctgccg
      781 cagccgtttc tccgcctgct tggtctccgc gatcgaacgc ttgagatatt cgcgcagctt
      841 gtcgtcgttc gccatcagga atcagcccct gtccaggagg tcgaagagtt cgtcgtcggt
      901 ggcggagtcg aggtcgatct cgtcgccggt gtcgtcgtcc gcgccgagcg gggcgtcgaa
      961 gcgggccagc agcgcgcgca ggcgggagac gacctcgccc cggccaccgg gttcggcgag
     1021 caggctcgcc tccagccgcc gcagcgcggt cagcgggtcc cccgccggtt cgccgtcccg
     1081 gtccgcctct gcctccgcca gcgccgacag gatgtagtcg gtcaccgcgg ccggcgaggg
     1141 atgatcgaag atcagcgtgg tcggcagggg cagcccggtg gccgtacgga gccggttgcg
     1201 caggtccacg gcggtcagcg agtcgagccc cagctcccgg aacgccctgg ccggcgggat
     1261 ctcctcgccg tcggcgtgcc gcagcaccgc cgcgacctcc gtgcggacga gcccgagcac
     1321 ggcctcgcgg cgctgctccg ggtcgagccc ggcgaaccgc gacgcgggtt cgggcgcccg
     1381 ccccccggcc gcgccgtcgt ccgccgcgcc gcccgcagat gacgtggcag atgacgtacg
     1441 cgaggcgtcg agccagaagc gggtgcgctg gaaggcgtag gtcggcaggt cgacgcggcg
     1501 cggatcggct ccgcggaggg cgacggccca gtcgaccggc acgccccgca cgaacgcctc
     1561 ggcgagcgac acgaggaacc gctccggccc gccctcgtcg cgccgcagcg tccctgtgac
     1621 cagcgcgggc gcgaccgcgg cggcgtccag ggtgtcctcg atgctcgacg ccagcaccgg
     1681 atgcgggctg atctccacga acgcggtgtg cccactggca gccagcgcgc gggtcgcggc
     1741 ctcgaaccgc acgggccgcc gcaggttcgc gtaccagtac tcggcgtcga gctccgcctc
     1801 cccggcccac tcgccgctga cggtcgacag catgggcacg gtcagcgcgc ggggcgtgat
     1861 cggggacagc gccttcagca gctcgtcgga gatcagctcg acctgggcgg agtgtgaggc
     1921 gtagtcgacg gggagccgcc ggttgcgcac cccctccgcg tcgagcgcgg ccagcagctc
     1981 gcccagagcg ctcacctcgc cggacacgac cacgctgccc ggcccgttga cgaccccgac
     2041 cgacaaccgg ccgtcccagg gcgcgatccg ggcctcggcc tcctccagtg gcagggccac
     2101 cgacgccatg ccgccgtcac ccgacagggt ccggatggcc tggctgcgca gggccaccac
     2161 gcgggcggcg tcgcgcagcg acagcccgcc cgccaccacg gccgcggcga tctccccctg
     2221 cgagtggccc accaccgcgt cgggacggac cccgtacgac tgccagagcc cggcgagcga
     2281 caccatgacg gcccacagca ccggctgcac cacgtcgacc cggtcgagcc ccggcgcgcc
     2341 ggggacgccg cgtacgacgt cgagcagcga ccagtcgacg aactcgctca gggcacgctc
     2401 gcactccgcg aggcgctccg cgaacacggg cgccgtctcc agcagcccgg cggccatgcc
     2461 gggccactgc ccgccctgac cggggaagac gaacacgacc ttcccggcga cgtcggccgt
     2521 gccgcgtacg acgtggccgg gcagggcgcc ctcgcgggtg agcgcggcca gtccggaggt
     2581 cagcccggcc gtgtccggcg cgaccacgac ggcgcgctcg cccagcagcg tcctggcgga
     2641 gacgagggag tgcgccacgt cgaccgggtc gaggtccgcc cggccgtcca ggtacgtcgc
     2701 gaggctgacg gcctggccgc gcagcgcctc gggcaggtgc cccgacagca cccacggcac
     2761 ggcgggcggt acggcgggcg gcgtggccgg cgtcccgacc ggctcctcgg cggcgggggg
     2821 ctgctccagg atcacgtgcg cgttcgtgcc gctcaccccg aacgacgaca cgcccgcccg
     2881 cctcgggccg ccgtcctccg gccagggccg cgcctcgtcg aggaggcgta ccccgccgct
     2941 cgaccagtcc acatgcgggc tcggctcttc gacgtgcagg gtcttcggca gcactccggc
     3001 gcgcatcgcc atgatcatct tgatcacgcc ggcgccgccc gccgcggcct gggtgtgcgc
     3061 gatgttcgac ttgagcgagc ccagccacag cggccggtcc gccggtcggt cctgcccgta
     3121 cgtcgccagc agcgcctgcg cctcgatcgg gtcgccgagc gtcgtgccgg tgccgtgtgc
     3181 ctcgaccacg tccacctcgc cggtcgtcag cccggcgttg gcgagagcct gccggatgac
     3241 ccgctgctgc gacgggccgc tcggggcggt caggccgttg gacgcgccgt cctggttgac
     3301 ggccgagccg cggaccaccg cgagcaccgg gtgattgttc ctgcgcgcgt ccgacagccg
     3361 ttcgaggagc agcagggcga cgccctcgcc ccagccggtg ccgtccgccg aggaggagaa
     3421 cgccttgcac cgcccgtcca ccgccagggc gcgctgccgc gagaactcga cgaacgtggc
     3481 gggcgacgac atcacggcga cgccacccgc cagcgccagg tccgactcac ccgtacgcag
     3541 cgactgcgcg gcgaggtgca gcgcgaccag cgacgacgag caggccgtgt cgacggtcac
     3601 cgccgggccc tcgaagccga acgtgtacgc cacgcggccc gaggcgatgc tgcccgcgct
     3661 gccgttgacg aggtagccct ccaggtcacc cgggatctcc tgcagccggg gcgcgtagtc
     3721 gtggtacatg acccccgcga agaccccggt gcggctgccc ctgagccgcc gggggtcgat
     3781 cccggcccgt tcgaaggcct cccacgccac ttcgagcagc agtcgctgct gcgggtccgt
     3841 cgcgagcgcc tcgcggggcg agatgccgaa gaaggcggcg tcgaagtcgg cgacgtcccg
     3901 caggaacccg ccgtgccggg tgtaggaggt gccgaggtgg tccggatcgg ggtcgtagag
     3961 ccgttcgagg tcccagcccc ggtcggcggg gaactccgac accgcgtccc cgccgcgttc
     4021 caccagccgc cacagcgcct ccggcgactc gatgccgccc ggcagccggc aggccatccc
     4081 gacgatgacg atcggatcgt ccgcgagcga cccggttgcg gtcgtctcgg cccgcaccgg
     4141 cgccttctcc gcccggccgc ccccgccgag caggccgtcc agcagatcgg cgatgccctg
     4201 gggggtgggg tggtcgaagg tgagggtggc ggggagtcgg agggtggttg tggtggtgag
     4261 gcggttgcgg agttcgacgg cggtgaggga gtcgaggccg agttcgatga gggggcggtc
     4321 gggggggatg gtgtgggggt gggggtggct gaggacggtg gcgacttcgg tgcggaccag
     4381 gtcgagcagg gccgcgctcc gccgttcggc ggtcagcgcg gcgagtcgcg tcgcgaggga
     4441 gccgtcctgc ccggcggccg cccgtaccgc tcggcggcgc ggggagatca ggcggcggag
     4501 caggggcggc ggcgcgtcgg tcgtcgtgtt caggcgcgcc ggtacgagca ccggcggctg
     4561 cgcggccgcg ccgaagacca ccgcgtcgaa cagggccagg gcgtggtccg tttccagcgg
     4621 acgcaggccg agcctggcca ggcgcctgtg gtcgttctga cccaggccgg cggtgagggt
     4681 gctggtgtgg gcccacagtc cccaggcgag gctggtggcg gggaggcgtt gggtgtggcg
     4741 gtggtgggcg agggcgtcgt ggaaggtgtt ggcggcggcg tagttggctt gggcggctcc
     4801 gccgagtagg ccgctgatgg aggagaacag gatgaaggcg gcggggttgt ggtggcgggt
     4861 gtggtggtgc aggtgggtgg cgccgtcgat tttgggggcg aggacggggt gcaggtggtg
     4921 gttgggggtg agggtgtgga gcggggtgtc gtgggtgatg ccggcggcat ggatgacggc
     4981 ggtgagcggg tggtccgcgg ggatggacgc gatgagggct tcgacggcgt gggggtcggt
     5041 gatgtcggcg gcggtgacgg tgacgtgggc gcctgcggtg gtgaggtcgc ggatgagggt
     5101 gtcggcgccg ggggtgtggt ggccgcgccg gccggtgagg tggaggtggc ggatgccgtg
     5161 ggtggtggcg aggtggcggg cgagcagggc gccgatgccg gtgaggccgc cggtgatcag
     5221 gacggtcccg tcggggtccc acccgcgcgg ctgaacctct tcggctttgt gttgcgtggt
     5281 gtgtgcgatc aggcgggggg tgagcagggt gccgtcgcgg agcgcggtgt ggggttcgtc
     5341 gtggtggcag gcggtggcgg cggcttgggg aagcaggccg gcagtctcgt ggtggtggtc
     5401 gatgaggtgg atgcggccgg ggtgttcggt ctgggcggag cggatcagcc cccagacggg
     5461 tgcggtgacc aggtcgatgg gctgttggct ggtggtggcg acggcgttgt gggtcaggac
     5521 gagcagccgg gtgccgctga ggcggtcgtc ggccaggaag gtctgcaggg cggccagggt
     5581 gtgttcggcc accgcatgcg ccgccgccac cgggttctcg cccgtcctgc tgttgctgcc
     5641 ggtggcgtgg gtggcctgct ccggctcgac gtgcgcggcg ttgtcggcgc cggtcgtgcc
     5701 gttgcgggcg ttgccgttcc cggtggcgtg gtggggggtg atcgggagga caatcacatc
     5761 gggggcgggt tcggcggcgt cgatggcgtc ggtgagggcg gtcaggtcgt cgtagtagga
     5821 ggtggtgacg gtccggcgga gggtgtcgtg gagttcccgg tcgccgagga cggcccaggc
     5881 ctcgtctgcc gccggctgga gttcgagggg tgaccactcg acccggaaca gactgctgtc
     5941 aggagtggat ccggacgtga ccagctgctc gctggagacg agccgagtgg tgagagtgtc
     6001 gatcgtggcg accggtgcgc cggtggggtc ggccacatgg agtgacagcg atccggcgtc
     6061 gccgagtgtg acgcgtaccc gcaggtcggt ggcaccggtg gcgtgcagcc gcaccccgct
     6121 ccaggcgaac ggcaggttgc tgtggccgtt cggcgtgccg tccagccagt gcagcgcggc
     6181 cccgtgcaac gccgcgtcga gcagcgccgg gtggatgccg tagtccgtca cgtcatcccg
     6241 ttcgtcctcg gggagggcga cctcggcgaa cagttcgtcg ccgcgccgcc aggcggcgcg
     6301 cagccctcga aacgccgggc cgtatccgag acctgcctcg tacaaccggt cgtacgccgt
     6361 gccgaggtcc acctgtacgg cgtcctccgg cggccaggcg gtgaggtcga agccgggttc
     6421 ggtgtcgtcc ctggccagta cggcggtcgc gtggcgggtc cagtctccgg tgtcgccctc
     6481 cggccgggag aagatctcca ggctgggccg gtcggagccg gtgacgatga tctgcacctg
     6541 tacgccgccg ctctccggaa gggcgagtgg ggcgtggagg acgagttcgt cgatggtggt
     6601 gtggccggtg tggtcggcgg cgtggagggc gaggtcgagg taggcggtgc cggggaggat
     6661 gggggtgtcg aagacggtgt ggtcggtgag ccaggggtgg gtggtgaggg agagggtgcc
     6721 ggtgtagacg gtggtgtcgt ggtgggcgag ggtgagggcg gcgccgagca gggggtgggc
     6781 ggtggtggtg aggccgaggt tcgcggggtc ggtctggcgg ggtggtgggg tgagccagag
     6841 gcgttcgtgc tggaaggcgt aggtgggcag gtcgacggtg gtggcggggc cgttgactgt
     6901 ggcccagtcg acgggggtgc cgtgggtgtg ggcgtgggcg gcggcggtga gggcggtggg
     6961 gggttcgggc cggtcccggc gtaacacggg aacggcgagg atgccctgtt cgctgtcgag
     7021 ggtctcgcgg atgaggccgg tgaggatgcc gtcggggccg atctcaagga acgtccgcac
     7081 tccctcgccc ggctccgggc cttcgtgcag tcgctgtacg acgtcggcga agcggacggg
     7141 gttgcgcagg tggcgggccc agtaggcggg gttggtgagg tcggtggggg tggcggtggt
     7201 gccggtgagg tcggagacga agggggtgac cggtccggtg ggcggggtga gggacagtgc
     7261 ggccacggct tgttcgaact cgtcgaggat cgggtccatg tggggggagt ggaaggcgtg
     7321 gctgacggtc agtgcccgga ccttgtgccc ctgctgccgg aagtgctcgg tgaggtgggt
     7381 gacggggtcg tggtcgccgc tgatgacggt ggaggtgggg gtgttggcgg cggcgatggt
     7441 gactctgccc ttgtaggcgg cgatttcgcg ggtgatgtgt gcttcggtgg cgttgatggc
     7501 ggtcatggcg ccgccgggtg gggcggtgtg catgaggcgg gcgcgggcgg cgacgagggc
     7561 ggcggcgtcg gggagggtga ggatgccggc ggtgtgggcg gcggcgatgg cgccgatgga
     7621 gtgcccggcc acggcgtggg gggtgatgcc ccacctggtg aggaggtggg tgagggcggt
     7681 ctggagggcg aacagggcgg gctgggtgta gagggtctgg tccagcaagg ccgggtcggc
     7741 gtcgccgagc aacacttcgc gtagtggtac gggtgtgtgc cgggccaggt gctggtcgag
     7801 caggttgatg gcctggtcgt aggcggtggc gaaggcgggg tgggcggcgt gcaggccgcg
     7861 tcccatgccg gggcgttggc tgccttgccc ggtgtagacg aaggcgacct tggcgggccg
     7921 ggcgatcccg gtcacgatcc cgccggcgga tgtgccgtcg gcgagggcgc gggtgcggtc
     7981 gaggagttct tgtcgtgtgg tgccggtgat gacggcgcgg tggtcgaacc gggcgcgggt
     8041 ggtggccagg gagtgcgcga cgtcggccgc acccagggtg gggtgacggt ccaggtggtc
     8101 ggccagccgg gcggcctggg cacgcagcgc ctcgggcgac cgcgccgaga ccacccaccc
     8161 cacggccggc gacggacggg cctggggtga ctcgagctcg gcctggtcgg gggcttgttc
     8221 gatgatgacg tgggcgttgg tgccgctgac gccgaaggcg gagacggcgg cgcggcgggg
     8281 gcgtgcgtgg tcgggccagg gttgggggtg ggtgaggagt tggaggttgc c
//
