LOCUS       NZ_VYTZ01000018        22784 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold18, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000018
VERSION     NZ_VYTZ01000018.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 159496)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 159496)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6439
            Orig. end                         :: 29223
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000018.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22784
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22784
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22784
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12784](+)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12784
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     misc_feature    769..787
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 21.17"
                     /tool="antismash"
     misc_feature    complement(773..791)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 20.18"
                     /tool="antismash"
     misc_feature    1412..1426
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.92"
                     /tool="antismash"
     misc_feature    1813..1826
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 18.36"
                     /tool="antismash"
     misc_feature    1822..1837
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.81"
                     /tool="antismash"
     misc_feature    complement(2208..2223)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 18.42"
                     /tool="antismash"
     misc_feature    2825..2839
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     misc_feature    complement(3133..3148)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.81"
                     /tool="antismash"
     misc_feature    3184..3197
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.13"
                     /tool="antismash"
     misc_feature    3186..3203
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 15.02"
                     /tool="antismash"
     misc_feature    complement(3207..3222)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.26"
                     /tool="antismash"
     gene            complement(3218..5524)
                     /locus_tag="F5972_RS32690"
                     /old_locus_tag="F5972_32695"
     CDS             complement(3218..5524)
                     /EC_number="2.7.7.59"
                     /GO_function="GO:0008773 - [protein-PII]
                     uridylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018655279.1"
                     /locus_tag="F5972_RS32690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32695"
                     /product="[protein-PII] uridylyltransferase"
                     /protein_id="WP_225312098.1"
                     /transl_table=11
                     /translation="MMRGEARSFAATRKDRAADIDRWLTDLFRTAATRPYAREEGSGGK
                     GGLPDERGHAAPIGISGVALVAVGSLGRGELAPGSDLDLVLLHNGREDVARIADRIWYP
                     IWDSGIGLDHSVRTVDEAVKVAREDLKAVLGLIQARHVVGDPELTRSAREAVLVEWRAD
                     SRRRLAELRASADKRAETGGELAFLLEPDLKDARGGLRDVQAMQAVAAAWVASAPGPRV
                     REAYELLLDIRHGLHLVTARGTDRLVLQEQDAVAGTLGMLDAEALMRRLAEAGRTISHA
                     FDATWRTVDRLLTGPAPRGRRPLADGVVEHGGEVVLARGVTPRSDPTLVLRAAAAAAEA
                     GLPLAPATVSALAAQSPPLPVPWPPEARGALVALLGAGRAAVPVWEELDQAGVLVKLIP
                     DWERVRHRPQRNPVHRYTVDRHLIETAAGAAAFTREVSRPDLLLISALLHDIGKGWPGD
                     HSTTGEIVARDIGARMGLPQADVEILATVVRHHLLLPETATRRDLDDPVTISRVAEAIG
                     SREVLELLAALAVADGSATGPAAWNSWKASLVSDLVRRVRSVLSGAPPAPAPALSPEQA
                     ALARHGGGAVRVNGSAVTVVAPDRPGLLWRAAGVLAAHRMAVRAASAASAGSTAVIEFV
                     VVPEYGSPPDPATLEADLRLVLAGRLDIEQRLARRARSMRPSRVPVAPPRVTLLDDASN
                     TASVVEVRAHDRPGLLWRIGRAFGECGLDVRAARVETLGAEAVDVFYVADRTGRPIVDE
                     QQRIQVREHVLAALR"
     gene            complement(5529..5867)
                     /locus_tag="F5972_RS32695"
                     /old_locus_tag="F5972_32700"
     CDS             complement(5529..5867)
                     /GO_function="GO:0030234 - enzyme regulator activity
                     [Evidence IEA]"
                     /GO_process="GO:0006808 - regulation of nitrogen
                     utilization [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018850023.1"
                     /locus_tag="F5972_RS32695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32700"
                     /product="P-II family nitrogen regulator"
                     /protein_id="WP_111699519.1"
                     /transl_table=11
                     /translation="MKLITAVIKPFKLDDVKAALEQFGIKGMTVSEASGYGRQRGHTEV
                     YRGAEYQVDLVPKVRVEVLAEEDDAEDVIDVIVKAAQTGKIGDGKVWSVPVDTVIRVRT
                     GERGPEAL"
     gene            complement(5864..7153)
                     /locus_tag="F5972_RS32700"
                     /old_locus_tag="F5972_32705"
     CDS             complement(5864..7153)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008519 - ammonium channel activity
                     [Evidence IEA]"
                     /GO_process="GO:0072488 - ammonium transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634826.1"
                     /locus_tag="F5972_RS32700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32705"
                     /product="ammonium transporter"
                     /protein_id="WP_204288654.1"
                     /transl_table=11
                     /translation="MITATALVLLMTPGLAFFYGGMTRAKSVLNMMMMSFVSIITVTLT
                     WVLYGHSLAFDAFGDGDNFINKLIGGGDAMGLQSLIDTATKDDGTGMPNLVFSAFQLTF
                     AIITVALISGAIADRAKFGAWVVFGIAWATLVYFPVAHWVWGGGWLANLGIEDFAGGTV
                     VHVNAGAAGLALAFVLGKRTGWRKDPMRPHNLTLVLLGVGLLWFGWFGFNAGSELAVDG
                     TAGLAFMNTQVATAAAAGAWILVEKLRDGHSTTLGVASGAVAGLVAITPACGFVDPWAA
                     LVLGLVAGAVCAYAVGLKYRFGFDDSLDVVGVHLVGGAIGAVSLGLIARYPFADGQNEG
                     LIYGGPISQLGVQALGPVAVGLYSFIMAYVIGKIIDKTMGFRIEQEDEVTGIDITTHAE
                     TGYDLGTVHSSGVTSVNGPVSAAQTKKVDA"
     misc_feature    complement(7280..7293)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.35"
                     /tool="antismash"
     misc_feature    complement(7281..7292)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.32"
                     /tool="antismash"
     misc_feature    7394..7409
                     /note="TFBS match to CsoR, Copper-responsive repressor,
                     confidence: weak, score: 22.24"
                     /tool="antismash"
     gene            complement(7440..8372)
                     /locus_tag="F5972_RS32705"
                     /old_locus_tag="F5972_32710"
     CDS             complement(7440..8372)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131223.1"
                     /locus_tag="F5972_RS32705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32710"
                     /product="RNA polymerase sigma factor RpoD/SigA"
                     /protein_id="WP_150939312.1"
                     /transl_table=11
                     /translation="MATGNRTHEQQVSDRDLLGTYLAEIGRVPLLTADQEVELAKRIEA
                     GLFAEQLLDSGRAEPKAADATDEELERIAVSGRRAKDEFIQANLRLVVAVARKYSGRGM
                     PLIDLVQEGNLGLVRAVEKFDYRRGYKFSTYATWWIRQSVGRSIHEQARPVRLPTHAGE
                     QMTRLMRVRRDMLAEFDAEPTDADLAAVLDLPIERVQELRRWASDPVSLQLGVGDEDET
                     ELGDMIADETWADPEQQAMATLEKERLEQWLTGLEGQIRDMLRWRYGLVDGREHTLTEV
                     GERYGIGRDRARRIERDALTRLRKMASAA"
     misc_feature    complement(8503..8517)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 16.45"
                     /tool="antismash"
     misc_feature    complement(8524..8539)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.95"
                     /tool="antismash"
     gene            complement(8598..9761)
                     /gene="hutI"
                     /locus_tag="F5972_RS32710"
                     /old_locus_tag="F5972_32715"
     CDS             complement(8598..9761)
                     /EC_number="3.5.2.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016812 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds, in cyclic amides
                     [Evidence IEA]"
                     /GO_function="GO:0050480 - imidazolonepropionase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019556 - L-histidine catabolic process to
                     glutamate and formamide [Evidence IEA]"
                     /codon_start=1
                     /gene="hutI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017545147.1"
                     /locus_tag="F5972_RS32710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32715"
                     /product="imidazolonepropionase"
                     /protein_id="WP_150939314.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.1e-24, bitscore:
                     80.5, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWPSDANSTVFTEIGLLFTADPEREEIRDAALVAENGVVRWIGPS
                     ADAPAADERVGVEGRAVIPGFVDSHAHLVFAGDRTEEFAARMAGRPYTAGGIRATVAAT
                     RAATIPELVSTTALLVAEMTTQGTTTFEIKSGYGLTVEHERRSLEIARQFTEETTFLGA
                     HVVPPETTADEYVELVTGPMLEACAPFARWVDVFCERGAFGEEHARRVLAAGRAAGLQV
                     RVHANQLGEGPGVRLACEMGAASADHCTYLADADVDALASSGVVATLLPGAEFSTRSPY
                     PDARRLLDAGVAVALATDCNPGSSFTTSMPFCVALAVREMGMTPLEAVRAATRGGARAL
                     RRTDVGALCVGSRADLVILEAPSYVHLAYRPGVPLVAQVWRGGRRLV"
     gene            10001..12784
                     /gene="lanL"
                     /locus_tag="F5972_RS32715"
                     /old_locus_tag="F5972_32720"
     CDS             10001..12784
                     /codon_start=1
                     /gene="lanL"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF038150.1"
                     /locus_tag="F5972_RS32715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32720"
                     /product="class IV lanthionine synthetase LanL"
                     /protein_id="WP_150939316.1"
                     /sec_met_domain="Pkinase (E-value: 1.3e-17, bitscore: 57.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.9e-44, bitscore:
                     144.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTGSAGVAEGTGADSHLLADIVMAAVRRGTGSRSAGEETRNGRD
                     WEIHTGTPWTYVTPAGCAMPAQGWKLHVSATQLSAAVVLARTAEVLVRRRVPFKFAATF
                     EELSGLLSRDVDRGTLGKFITVYPPDDAAAVSIAEELHSATYGLPGPPILSDRPYRPGS
                     LVHYRYGVFSATSVLDNDGTYASLLVAPDGTTVKDSRNAWYSPPAWAVSPFPSGRAPAR
                     TTAPEAVLLADRFVVRQAIRHSAKGGVFLAEDRLSGARVVVKQARPHLGSTLQGRDECD
                     QLRHEAAMLDLFGPPGITARKVDLFEQSDNLFLVQEHLDGTMLTAWAGERTGPDRRGHD
                     EVLTVVRGLTALVAAVHEQGYVLRDLTPNNVLVTADGGCRLVDLEMAAIPGTPVARAFT
                     PGFAPPEQMNAPRHAPAPGVEADLYALGATVFFLTTGCPPMLADDGPDEERSWGDRVRT
                     LVSVATAGDPVAEAFAPMISGLMREERSERWDLRRVEEFLAKLDAEPRPFVSVRPVRHL
                     GADEGDRLLRDGVAHLVRTMARPAPGGPDPLRLWPVTGFGADADPCAVQYGSAGVLTVL
                     ASLLDGPFARDPGLPATWRSDVTGALADAAGWTLRRLDREPRPSPGLYFGRAGVAWGLH
                     EAGRVLGDDDMCAAGVELASGLPDSWPNPDVCHGLSGTGLTLLHFWRATGDGRFRDKAG
                     RCADSLLAAAEHTAGTVLWPIPATFASSLAGVVHYGFAHGVAGVGAFLLAAGLALGRDD
                     CLETATAGGRTLVEAAEITDGAAWWDQGPAGGARMPHWCNGSSGVGTFLIRLHRATGDR
                     RFLDAARGAARTVHLSRVSSGSSQCHGLAGDGQFLLDMADLLGEPAYHDQAGELAAYLW
                     ARAVSRDGLLLVPDENGFELSAGWNTGLAGVLDFLHRLRHGGPRSWMADAGDGAAR"
     gene            12781..14574
                     /locus_tag="F5972_RS32720"
                     /old_locus_tag="F5972_32725"
     CDS             12781..14574
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012546.5"
                     /locus_tag="F5972_RS32720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32725"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_150939318.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 8.6e-24, bitscore:
                     77.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAPVITGTAGEETAHRSSETRRINFRFSRRGRYAACLSARGRGP
                     LVPELWDLGGGTPVPMTLGRPAGESSWSTVVPTDGGRILLGRAQAGGVHRLLLITPGEA
                     PAPMPATFHGGGFRLVAGGPEGAAALAFHGAGEGRTTVWRVPAEPGPLEAVATVPAVLG
                     GGVWLDASGRRLALSRHGDEPGTVVLDLPDGSLSPLPGLAGGEHLLLAAPRGGVLLTTL
                     RHEGAYRLGVRGTDDGPTVFPRPLNEIDGAVTPLAFDPEGRRLALLATRGVRSHLLVYD
                     LTTEEIREAALPAGALYPSAHWSTAGLHVIHTTPDRPYAPLTVLNASGAPATRRGGERA
                     TARAQSYDGPGGRIEAVVYGDPARSRQVVLALHGGPEAAWQLSFDPLFRQMSARGIAVV
                     APNQRGSTGYGAAHRDAIRGAWGGPDLADILHLGRVVGAGRGPGACRPMLYGASYGAYL
                     ALLAVAADPHLWSRAAVVAPFLSGRELYTDGPATVRAMLDRLGGLEEITDDELGPRDLL
                     RLAGRLRLPLLVVHGEHDDVIPVSHSRRLRDRLAEVAPPGAELTYLEVTGAGHDPLTGH
                     GAHLVRDRLVHFLDTGSAQLS"
     gene            14712..14840
                     /locus_tag="F5972_RS37610"
     CDS             14712..14840
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="F5972_RS37610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_191910429.1"
                     /transl_table=11
                     /translation="MELDVKALDMLPASEESELYPCQITCAGGRTCGGWTCWSTDY"
     gene            14901..15029
                     /locus_tag="F5972_RS37615"
     CDS             14901..15029
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF038157.1"
                     /locus_tag="F5972_RS37615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ALQxL family class IV lanthipeptide"
                     /protein_id="WP_191910430.1"
                     /transl_table=11
                     /translation="MELDVNALDMLPAPEESRLMACTVTCGRSCYGATGTCGITQI"
     gene            15238..17037
                     /locus_tag="F5972_RS32725"
                     /old_locus_tag="F5972_32730"
     CDS             15238..17037
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012869.5"
                     /locus_tag="F5972_RS32725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32730"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_150939320.1"
                     /transl_table=11
                     /translation="MPGPAPRSSEEQVSHGHGDRLIAALSRETWMPLAATATGSIATTA
                     VALALPAALAAAVNAVVTGRGALTATAYLALLLAGAALAEVATGITSTTATASAIGTLR
                     LRVAGHLLSADVSGATRFSTGELVNRLVSNTATAGSAPVTLLGTITGVAASAGAVVALF
                     AVDPRAGLAFLAGTPVLIVVLRVFVSRVSGLYDEYQSAQGRLAARLTETLAGIRTVRAA
                     GTANREIDRVLRPLADLSSTGHALWRAQSRTVWQIMLLMPLVEILVLAVAGLGVAEGRL
                     TPGALVAVAGYAALGLTFVEQIDPLLGLAYGRSAAVRVLEVLALPVLPAGRRRLPDGPG
                     ALSFRGVTVTRGDTRVLDDIDLEIPAGALTAVVGRSGAGKTTLAMLAGRLTEPDHGRVL
                     LDGRRLSDLDPGCLRDAVAYAFERPALLGGDIASAIAYGTARTTREAVRAAARAAEVDD
                     VVSRLPLGYDTPAAGAPLSGGEIQRLGLARALLRRARLTILDDATSGLDTVTEAQVTRT
                     LVEGMRGRTRLVVAHRPATAARADLVIWLEAGRVRGRGTHRELWRHRDYRDLFAPDALD
                     SRGEPHRGEPAGVASRQESSCPR"
     gene            17025..18839
                     /locus_tag="F5972_RS32730"
                     /old_locus_tag="F5972_32735"
     CDS             17025..18839
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018653862.1"
                     /locus_tag="F5972_RS32730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32735"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_225312099.1"
                     /transl_table=11
                     /translation="MSAVTTARRQSPPASPPPAGDRAQGPWRLLAALLRRRPRPLALVM
                     AWSVVEAAPALLSGLLVAMAVDRGFRAGRPGLGLVLLGLLAAAMLVGAIATRLMFPHLA
                     AVVEPLRDDLVRAVVEATVTHASAGEQAPDGAAVNRLTEQIETVRALLSAVLRNTRQVG
                     VAVVAAVAGLLLLSPLAAAVVAGPVLIAVFAFVRLLRLLAARQRDLLLAGERLTAEVTP
                     TLGGLRDIAACGARDQARESVRSLVTAQAAAMRALAWAGARRRLVVTIGAHVPMVALLL
                     AAGPLTASGRLTAGEIVGALTYLSTGLEPAVRTLLGTVGSWGITLAVTAQRLGDVVTPP
                     PPREEPACVPETPVAHDLRTDRLTFAYSPRAEPVVRELDLTVGEGEHLVVVGPSGIGKS
                     TLAMLLSGLRRPTGGVVRLGGLALDAVPRQHLHEAVALVPQEAYVFAGTVRENLGYLRP
                     AGEAAADERLLAAADAVGAGPLLTRLGGLDGAIDEPSTLSAGERQLVTLARAYASPARI
                     VILDEATCHLDPAGEARAEAAFAARRGTLIVIAHRVSSAARADRVLLLDGARAITGTHR
                     DLVTRSPLYADLVGHWNHDAPGPDRLPE"
     gene            18890..19927
                     /locus_tag="F5972_RS32735"
                     /old_locus_tag="F5972_32740"
     CDS             18890..19927
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012893852.1"
                     /locus_tag="F5972_RS32735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32740"
                     /product="radical SAM protein"
                     /protein_id="WP_150939322.1"
                     /sec_met_domain="PF04055 (E-value: 2.1e-18, bitscore: 60.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 3.5e-08, bitscore: 27.0,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRHPGPTDIIWDITYACPLRCTHCYSESGRRPARQLGHEDMLRVA
                     DAIVSLGPRAVEFAGGEPLLVRGVHEVAERISRAGVEVNLYTSGWTVTPAAAEEAARVF
                     TRITVSVDGADAATHDRIRGRAGSFDRAMNALALLDDVSRRRTARGDAPVMFGVDCAVM
                     RGNFDQMGDLCTTVTSRFGRIRFLTFGAAVPSGLASRPGFGDLELLTGEQVRTLTSPEH
                     HDTLRARVPSSVVVNTNDNAMLLMRPELVERYGFPLLQIEPDGEVRAMPIYEGTVGSLL
                     SEDPAVLWERAVARWSDPFVVETLSAVRTWADWAEATRRIDYRFGSDAVRRRIDRRPDY
                     EATPV"
     gene            complement(19958..21301)
                     /locus_tag="F5972_RS32740"
                     /old_locus_tag="F5972_32745"
     CDS             complement(19958..21301)
                     /EC_number="3.5.3.13"
                     /GO_function="GO:0016810 - hydrolase activity, acting on
                     carbon-nitrogen (but not peptide) bonds [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546583.1"
                     /locus_tag="F5972_RS32740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32745"
                     /product="formimidoylglutamate deiminase"
                     /protein_id="WP_150939324.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 1.1e-43, bitscore:
                     142.9, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHVTYWCEMAWLPPGEVVESVAVAIEGSRIGDVRPGVPPPPGAER
                     LAGLTLPGLANCHSHAFHRALRGHTQTGRGDFWSWRERMYAVAEALDPDRYLALATATY
                     AEMALAGITAVAEFHYLHHGPGGTPYADPNAMGEALVEAARRAGLRIALLDTCYLTGGI
                     GDALAGPQVRFGDGDAERWAARADALARAHEGARDVEIGAAIHSVRAVPPEQMHVVVDF
                     AHRHTGPLHAHVSEQRAENEACVEAYAATPVQVLHDHGALGPRSTAVHATHLSDVDVAL
                     LGGSTSHVCMCPTTERDLADGVGPARRLLDAGSPVTLGSDSQAVIDLFEEARAVELDER
                     LVTGERGHWPAADLLHAATAAGQASLGFPDAGCLVPGAWADLVSVRLDSVRTAGATRAS
                     AVASVVFAATAADVHSVVSGGRRVVTDGRHVLGDAGALLREALAPLIP"
     gene            complement(21366..22052)
                     /locus_tag="F5972_RS32745"
                     /old_locus_tag="F5972_32750"
     CDS             complement(21366..22052)
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (3-166). E-value: 2e-09. Score:
                     29.5. Matches aSDomain:
                     nrpspksdomains_F5972_RS32745_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131220.1"
                     /locus_tag="F5972_RS32745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_32750"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_150939326.1"
                     /transl_table=11
                     /translation="MRPTALITGASRGIGAAIARALAPTHDLLLGGRDGTALDALCHEL
                     PGSRPWAVELTDLTPAEVEGIERLDLLVHSAGIARLGHLADTPAEVWRRTLEVNVVAVA
                     ELTRLLLPALRAARGHVVLINSGAGQRANPNWGSYAASKFALRAYGDVLREEEQPNGVR
                     VTSIFPGRVGTDMQRDVREQEGEPYEPGRYLEAESVARAVLAAVTATPDAHVTEITVRP
                     AAGPTR"
     aSDomain        complement(21555..22043)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS32745_PKS_KR.1"
                     /evalue="2.00E-09"
                     /label="F5972_RS32745_PKS_KR.1"
                     /locus_tag="F5972_RS32745"
                     /protein_end="166"
                     /protein_start="3"
                     /score="29.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TALITGASRGIGAAIARALAPTHDLLLGGRDGTALDALCHELPGS
                     RPWAVELTDLTPAEVEGIERLDLLVHSAGIARLGHLADTPAEVWRRTLEVNVVAVAELT
                     RLLLPALRAARGHVVLINSGAGQRANPNWGSYAASKFALRAYGDVLREEEQPNGVRVTS
                     "
     CDS_motif       complement(21984..22037)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS32745_0001"
                     /evalue="6.50E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="F5972_RS32745"
                     /protein_end="23"
                     /protein_start="5"
                     /score="15.6"
                     /tool="antismash"
                     /translation="LITGASRGIGAAIARALA"
     misc_feature    complement(22757..22772)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.23"
                     /tool="antismash"
ORIGIN
        1 gcgctctccc cgtccgtacg cggaaccgcg gtgggaccgg tgtcggaagg acggcggaac
       61 caggccgact cgaccgaggc gaagatcggc aggaactcgt cgccgcgctc cagcggcgag
      121 tcctccaccg ccggcagcgg accggtcgcc gacgcgaggc ccccggagcc gtcggctcgc
      181 cccatcgcgg gcggcggcgg gaaggcggtc ggccccgtgt ttcccggcga ccccgcgctc
      241 cccggcgccg gagcgaagac gttcggtccc gtgtctcccc gcgccggggt gaacgcgctg
      301 ggtcccgtgc tctggggaga cggcgggaac gcgttcggac cggtgctcgc cggggaaccc
      361 gcgctctgcg gcggcgggaa ggcgttcgga cccgtgccct gcgaggacga cgggaacgcg
      421 ttcggcccgg tgccgtgaac ggagggggtg aacgcgttct cacccgtgct ctgcgccgac
      481 ggcgggaagg cgttcggccc ggtgccctgc ggggacggcg gaaaggcgtt cggcccggtc
      541 gtgccggccg gcgtggccgt gtcccggcgc gggagcgggg tcggcccggt gggcagcgac
      601 ggccaggagg attcggaccg gcctggcgcg ggctcctcac ccgtcggcgt gccgaacgcc
      661 ggaggccacg acgcgcccgg ctgctcgccg aaggccgggc gggggagatc cgcgtccgga
      721 gaccctcccg gtgctccggg catcggctgc ggtcccgagt tccccgtgta cgtgtttcct
      781 gtatacgcgc tttcggtcgg cggcgcctcg gcggggcccg gcgggccgta cgggtgctcg
      841 gccggcgcgg gcggcgcctc cctgaccgga gcgccgaagg cggagaagcc gcccgagccg
      901 ttcccgccgg acccggcgcc gctcggcgcc gggggccggc gcgatcccac gccgccggcc
      961 gcgccgttgc cggggttcca cggctcgaac ggacccgctc ccggcgcctg gccggccggg
     1021 ttgggctcgg cgaacgcctg ccgggccggc aggccggccg cggtctgccc gaccgggacg
     1081 gacggacgcg gcatgagggg ctggtcggcg ttggagatga gctgcgcggg gaacagcacc
     1141 atcgcgatga tgcccgcgcc gtcaccccgg cgcagttgca cccggatgcc gtggcgcagc
     1201 gcgaggcggc cgaccacgaa gaggcccatc cggcgggaga ccgacacgtc gatcgtgggc
     1261 ggctcggcga ggcggcggtt gatctccgcc agttcctcgg cggacatgcc gatcccggcg
     1321 tcggtgaccc cgagcatcac ggccccgccc tcgaccgggc tactggagac cacgaccttg
     1381 gtgttgcgcg gcgagaaggc gatggcgttc tcgacgagct cggccaggag gtggacgacg
     1441 tcgttggcgg cgtgcccggc cagggcgatg ctgcgcggga tccggacgac gacccgctcg
     1501 tagtcctcga cctccgacag cgaggcgcgg accacgtcga ccagccgggc gggctggctg
     1561 cgcttgcgcg gcggctcgtg cccggcgagc accaggaggt tctcactgtt gcggcgcatg
     1621 cgggtggcga ggtggtccag cttgaacagg tcggcgaggc gccggccgtc ctcctcaccc
     1681 cgctccaggc cgtcgatcag cgagatctgc cgctccacca gcgtctgggt gcggcgcgac
     1741 aggttcacga acatcgagtt gacgttggcg cgcaggcgcg actcctcggc ggccagccgt
     1801 acggcctgca ggtggacctc gtcgaaggcc tgggcgacct cgccgatctc gtcggtgctg
     1861 ccgaccgcga tcggctgcac ctgcgactcc cggtcggggt cgtccgactc gcgcatccgc
     1921 cgcacgatct cgggcagccg gcgcccggcg atgtcgagcg cctccacccg caggcggcgc
     1981 agcggccgga ccatcgaccg cgcgatgagt gcggtggtgg ccagcacgag caccaggagg
     2041 gcgaggatca gcgccccggc gatgagggcg ttgcgctgtt cggccgactg caggtcacgg
     2101 gtccggccct gcaccagcga cgacacccgg ccctcgacgg ccgacatctg ctcgatggtc
     2161 ttggtgctgt cctggaacca ccgctgagcc gtggtgtccc tgctgcggta acggctgagt
     2221 gactggttct gcaggcccag cctgagcgcc cacgacttgg tcagctcgcc gttcacgacg
     2281 ctcgggtcgg cgaagagggt caccaggcgg gccgcctcgg cctgcggggc ctccgagtag
     2341 aacgtcgcga ggtagctcgc ctggcgcgac tgggcggcca ggaagtcctg cagctcgaag
     2401 gtggtgaagg tctggttgcg ttccatgaac tcgcgggtga gggcggcccg ctgcagggcc
     2461 acctcctcct tggcgtgggc gagaccgccc agggcgcgga cgttgcccac gatctcgggc
     2521 gcgccgtcgc tcgcgcccag ttcgtcgtgc aggcgcagga tgttggcgat cagcgcgctg
     2581 tagtcctccg gcgcgccgtt ggcgcggatg ccggcgaggc tggcgaaacg gctggtgagc
     2641 tgctgggcct gctcccccgc ccgcgcgccg tagtccgcgt cgacgttctt gaggtcggcc
     2701 ctcacctgtt gcaccagggg gtcgaccacc gcgcgctgct gggcgcgggt gagctcggtc
     2761 tggccgtcga tgtcgaactt gcgcctggtg ttgcctcccc agacgaacag gtcacgttcg
     2821 agggcgagct gctcggccag gtcccgcagg tgcaccgagt actccgccgc cgacctggtc
     2881 cgctggtagc cggtcaggct gtccatcgag ctgacgacgc ggagaccggc gaggagcacg
     2941 gccacgagcg tcggggcgag gatcagcgcc gtcaggcgtg tgggaaccct ccagttgcgc
     3001 ggtgagaacg ggctcctccg cctgcggtta tcggtattcg actgctccat gctcaccggc
     3061 cccgccatcg ttcggcctgc cttcacgcgt ctggacagca tgaagtgaca tagctctata
     3121 agcggggaca attcgaccac aaggtcatca aggtgagcgg ccctacccct gccgcagcac
     3181 cccaattgtt accaagaggt gaggatcgtg acccttatca cctgagggcc gcgaggacgt
     3241 gctcccgtac ctggatccgc tgctgttcgt ccacaatggg gcggcccgta cgatccgcca
     3301 catagaagac atccaccgct tctgcgccca gagtctccac acgcgcggcc cgtacgtcaa
     3361 gtccgcactc gccgaaggcg cggccgattc gccacagcag accgggcctg tcgtgcgctc
     3421 tcacctccac cacactcgcc gtgttggacg cgtcgtcaag cagggtgacg cgtggcggcg
     3481 ccaccggcac ccgggaaggc cgcatggacc tcgcccgccg ggccaggcgc tgctcgatgt
     3541 cgagccgtcc ggccaggacg aggcgcaggt cggcctccag cgtcgccgga tccggcggcg
     3601 agccgtactc ggggacgacg acgaactcga tgacggcggt cgacccggcg gacgcggcgg
     3661 aggcggcgcg caccgccatc cggtgcgccg cgagcacccc ggccgcccgc cacaacaggc
     3721 ccggccggtc cggcgcgacc acggtgaccg cgctgccgtt cacccgcacc gctccgccgc
     3781 cgtgccgggc gagcgccgcc tgctcgggcg acaacgcggg cgcgggcgcc ggcggcgcgc
     3841 cggacagcac cgacctcacc cgccggacca ggtcggagac cagggacgcc ttccaggagt
     3901 tccacgcggc cgggccggtc gcggagccgt cggccacggc gagcgcggcc agcagttcga
     3961 ggacctcccg ggaaccgatc gcctcggcca cccgggagat ggtcaccggg tcgtcgaggt
     4021 cccgccgggt ggcggtctcg ggcagcagca ggtgatgccg caccaccgtg gcgaggatct
     4081 ccacgtcggc ctgcggcagg cccatccggg cgccgatgtc ccgggcgacg atctcaccgg
     4141 tggtggagtg gtcacccggc cagcccttgc cgatgtcgtg caggagcgcc gagatgagca
     4201 gcaggtcggg gcgggacacc tcgcgggtga aggcggcggc cccggccgcg gtctcgatga
     4261 ggtgccggtc cacggtgtac cggtggaccg ggttgcgctg gggacggtgc cgcacgcgct
     4321 cccagtcggg gatcagcttg accagcacgc cggcctggtc gagctcctcc cagaccggta
     4381 cggcggcgcg gcccgcgccg agcagcgcca ccagtgcgcc gcgggcctcc gggggccacg
     4441 gcacgggcag cggaggcgac tgggcggcga gcgcgctgac cgtcgccggc gccagcggca
     4501 gccccgcctc ggcggcggcc gccgccgccc gcagcacgag cgtggggtcg gagcgcgggg
     4561 tgacgccgcg ggccagcact acctcgccgc cgtgttcgac gacgccgtcc gcgagcggcc
     4621 gccgtccgcg cggcgcggga ccggtcagca gccggtcgac ggtgcgccag gtggcgtcga
     4681 aggcgtggga gatggtgcgg ccggcctccg ccaggcggcg catcagcgcc tcggcgtcga
     4741 gcatgccgag cgtcccggcg accgcgtcct gctcctggag gaccaggcgg tcggttcccc
     4801 gggcggtgac caggtgcagc ccgtgcctga tgtccagcag cagttcgtac gcctcgcgga
     4861 cgcgggggcc gggggccgag gccacccagg cggcggccac ggcctgcatc gcctgcacgt
     4921 cgcgcaggcc gcccctggcg tccttgaggt cgggttcgag gaggaaggcc agctcgccgc
     4981 cggtctcggc gcgtttgtcc gccgacgccc gcagctcggc cagccggcgc cgggagtcgg
     5041 cccgccactc cacgagcacc gcctcccggg cggaccgggt cagttccggg tcgcccacca
     5101 cgtgccgcgc ctggatcagc ccgagcacgg ccttgaggtc ctccctggcg accttcaccg
     5161 cctcgtccac ggtgcggacg gagtggtcga gaccgatccc ggagtcccag atggggtacc
     5221 agatgcggtc ggcgatcctc gccacgtcct cgcgcccgtt gtggagcagg acgaggtcca
     5281 ggtcgctgcc gggggcgagt tcgccccggc ccaggctgcc gaccgcgacc agggccacgc
     5341 cgctgatccc gatgggagcg gcgtggcctc gctcgtcggg gaggccgccc ttccctcccg
     5401 atccctcctc ccgcgcgtac ggccgggtgg ccgccgtgcg gaacagatcg gtgagccatc
     5461 tgtcgatgtc cgcggcccgg tccttgcggg tcgcggcgaa cgagcgcgcc tcccctctca
     5521 tcatccggtt acagcgcctc cggtccgcgc tccccggtgc ggacccggat gaccgtgtcc
     5581 acgggaaccg accagacctt gccgtcgccg atcttccctg tctgcgccgc cttgacgatg
     5641 acgtcgatga cgtcctccgc gtcgtcctcc tcggccagga cctcgacccg gaccttgggc
     5701 accaggtcga cctggtactc ggcgccccgg tagacctcgg tgtggccgcg ctgacggccg
     5761 tagccgctgg cctccgagac cgtcatgccc ttgatgccga actgctccag ggcggccttc
     5821 acgtcgtcca gtttgaacgg cttgatgact gcggtgatga gtttcatgcg tcgaccttct
     5881 tcgtctgtgc cgcggaaacg ggcccgttga cggaggtcac tcccgaggag tgaacggtgc
     5941 cgaggtcgta cccggtctcg gcgtgggtgg tgatgtcgat gccggtgacc tcgtcctcct
     6001 gctcgatccg gaagcccatc gtcttgtcga tgatcttccc gatcacgtag gccatgatga
     6061 aggagtagag gcccaccgcg acagggccga gcgcctggac gccgagctgc gagatcgggc
     6121 cgccgtagat gaggccctcg ttctggccgt cggcgaaggg gtagcgggcg atgagaccga
     6181 gggagaccgc gccgatcgcg ccgccgacca ggtggacgcc gaccacgtcg agcgagtcgt
     6241 cgaagccgaa gcggtacttc aggcccacgg cgtaggcgca gaccgcgccg gccacgaggc
     6301 cgagcacgag cgccgcccac gggtccacga aaccacaggc aggggtgatg gcgaccagac
     6361 cggccaccgc gccggaggcg acgccgaggg tggtggagtg gccgtcgcgc agcttctcca
     6421 cgaggatcca ggcgccggcg gcggcggccg tggcgacctg ggtgttcatg aacgcgagac
     6481 cggcggtgcc gtcgacggcg agctcggagc ccgcgttgaa gccgaaccag ccgaaccaca
     6541 gcaggcccac gccgagcagg accagggtga ggttgtgcgg gcgcatgggg tccttgcgcc
     6601 agccggtccg cttgccgagc acgaacgcga gcgcgaggcc cgcggctccg gcgttcacgt
     6661 ggacgaccgt gccgccggcg aagtcctcga taccgaggtt ggccagccag ccgccgcccc
     6721 agacccagtg cgcgaccggg aagtagacca gcgtcgccca ggcgatgccg aagaccaccc
     6781 aggcgccgaa cttggcgcgg tcggcgatgg cgccgctgat gagggcgacg gtgatgatcg
     6841 cgaaagtgag ctggaaagcg gagaacacca ggttcggcat gccggtgccg tcgtccttgg
     6901 tggccgtgtc gatgaggctc tgcagaccca tggcgtcgcc gccgccgatg agcttgttga
     6961 tgaagttgtc cccgtcaccg aaggcgtcaa aggccagtga gtggccgtac agaacccagg
     7021 tgagggtaac ggtgatgatg ctgacgaacg acatcatcat catgttcagg acgctcttgg
     7081 ccctggtcat gcccccgtag aagaacgcga gcccgggcgt catcaacagc accagcgcgg
     7141 tcgctgtgat catccaggcg gtggtaccgg tatcgatctt caccgacgcg gccctcctta
     7201 catttggcgt gtggccggtt atcactccct cagtggcgtg gtcccgggct tcctcggccg
     7261 gctggctcac tgacgttggc gaaagcgtgt tcttccgccg tttcagctca tgaccatgcg
     7321 tgtttcactg gcgtgaaact cgccgatccc gtgtttcggc caggtttcgg acgtgctggt
     7381 aacgacaaaa cgcgcacccc tggggggtgc gcgtcgtcgt gataccggta ggccggccgt
     7441 caggcggcgc tggccatctt ccgcagccgc gtcagcgcgt cgcgctcgat gcgccgggcg
     7501 cggtcacggc cgatgccgta acgctcgccc acctcggtga gggtgtgctc ccggccgtcc
     7561 accaggccgt accgccagcg gagcatgtcg cggatctggc cctccaggcc ggtcagccac
     7621 tgctccaggc gctccttctc cagcgtggcc atggcctgct gctccgggtc cgcccaggtc
     7681 tcgtcggcga tcatgtcgcc cagctcggtc tcgtcctcgt cgcccacccc gagctggagc
     7741 gagacggggt cggacgccca gcggcgcagc tcctgcacac gctcgatcgg caggtcgagc
     7801 accgcggcga ggtcggcgtc ggtcggctcg gcgtcgaact cggccagcat gtcccggcgg
     7861 acccgcatga gccgggtcat ctgctctccc gcgtgggtgg gcagccgcac cggccgcgcc
     7921 tgctcgtgga tggagcggcc gaccgactgc cggatccacc aggtggcgta ggtcgagaac
     7981 ttgtatcccc ggcggtagtc gaacttctcc accgcccgga ccagcccgag gttgccctcc
     8041 tgcaccaggt cgatcagggg catcccccgc cccgagtact tcctcgccac ggcgaccacg
     8101 agacgcaggt tggcctggat gaactcgtcc ttcgcccgcc gccccgaaac ggcgatgcgc
     8161 tcgagctcct cgtcggtcgc gtccgcggcc ttgggctccg cccgcccgct gtcgagcaac
     8221 tgctcggcga acaaccccgc ctcgatccgc ttggcgagct cgacctcctg atcggcggtc
     8281 agcaacggaa cgcggccgat ctcggccaga tacgtcccca gcagatcccg gtcagagacc
     8341 tgctgctcat gcgtccgatt ccccgtcgcc atacgatggc acctcgttcc gccgcccgcg
     8401 atatgcaata agtgagccgg cgaaccggac acgtccgccc cgctcggcgt ggcctccggc
     8461 ttcctgctcc tgacccggtc aacggccggt ccatggcaaa gattccccaa atgaatacga
     8521 ccggggaatg gtttacagtt cctccccaag gaggatgcgg ggccgggaaa aaagccgatt
     8581 acccagatct cgcaggtcta aacaaggcgg cgtcccccgc gccacacctg tgccaccagt
     8641 ggcacgccgg gccggtacgc caggtggacg tacgacggcg cctccaggat gacgaggtcc
     8701 gcgcgggagc cgacgcacag ggcgccgacg tcggtgcgcc gcagcgcccg cgcgccgccg
     8761 cgcgtggccg cgcgtacggc ctccagcggc gtcatgccca tctcccgtac ggccaaggcg
     8821 acgcagaacg gcatcgacgt ggtgaacgac gacccggggt tgcagtcggt cgcgagggcc
     8881 acggcgaccc cggcgtcgag cagccgccgc gcgtccgggt acggcgacct ggtggagaac
     8941 tcggcccccg gcagcagcgt ggcgaccacc ccggaggacg cgagcgcgtc cacgtcggcg
     9001 tcggcgagat aggtgcagtg gtcggccgac gccgccccca tctcgcaggc cagccgcacg
     9061 cccggcccct cccccagctg gttcgcgtgc accctgacct ggagcccggc cgcgcggccc
     9121 gccgcgagca cccgcctcgc gtgctcctcg ccgaacgcgc cgcgctcgca gaacacgtcc
     9181 acccatcggg cgaacggcgc gcacgcctcc agcatcgggc cggtcaccag ctcgacgtac
     9241 tcgtcggcgg tggtctccgg cgggacgacg tgcgcgccca ggaaggtggt ctcctcggtg
     9301 aactgccggg cgatctccag gctgcggcgc tcgtgctcga cggtgaggcc gtacccgctc
     9361 ttgatctcga aggtcgtggt gccctgggtc gtcatctccg cgaccagcag cgcggtcgtg
     9421 gagacgagct cggggatggt cgccgcccgg gtcgcggcga cggtcgcgcg gatgccgccc
     9481 gccgtgtagg gccggccggc catccgcgcg gcgaactcct cggtgcggtc gcccgcgaac
     9541 acgagatggg cgtggctgtc gacgaacccc gggatgacgg cgcgtccctc gacgccgacc
     9601 cgctcgtcgg cggccggggc gtcggccgag ggcccgatcc agcggaccac cccgttctcc
     9661 gcgaccagcg cggcgtcccg gatctcctcc cgctcggggt ccgccgtgaa cagcagtccg
     9721 atctcggtga aaaccgtgga attcgcgtcg ctcggccaca cgtctcctga tcctcgccag
     9781 gccccgcgcc gcgcaaaccc gccgggccca cctgggatcc cctattaggg gccgaccagt
     9841 gccaccaagt cgttctcaga ccgcggcaga caagtcgtca ctagccgccg acaagggccg
     9901 ttgccgactc tgcgttcagg cggagcgcgg cgccggccgg gacgaccgga cgatatccga
     9961 cgccgagcct cgtggacgag acgacaggag tgacggcggc gtgaacacag gcagcgcggg
    10021 cgtggccgaa ggcaccggcg cggactctca cctgctcgcg gacatcgtca tggccgccgt
    10081 gcgccggggg acggggtccc gctcggcggg tgaggagacg cggaacggcc gggactggga
    10141 gatccacacc ggcacgccgt ggacgtacgt gacgccggcc gggtgcgcga tgccggcgca
    10201 ggggtggaaa ctgcacgtct cggcgacgca gctgtcggcg gcggtcgtgc tggcgcggac
    10261 ggccgaagtg ctggtgcggc gccgggtgcc cttcaagttc gccgcgacgt tcgaggagct
    10321 gagcggcctg ctgtcgaggg acgtcgaccg cggaacgctc ggcaagttca tcacggtgta
    10381 tccgcccgac gacgccgcgg ccgtgtcgat cgccgaggag ctgcactccg ccacctacgg
    10441 cctgcccggc ccgccgatcc tgtccgaccg gccctatcgg cccgggagcc tggtccacta
    10501 ccgctacggc gtgttctcgg ccacgagcgt gctcgacaac gacgggacct acgcctccct
    10561 tctggtcgcc cccgacggca cgaccgtgaa ggacagccgc aacgcctggt actcgccgcc
    10621 ggcctgggcg gtcagcccgt tcccttcggg ccgggcgccg gcgcgcacca ccgcgcccga
    10681 ggcggtgctg ctggcggacc ggttcgtggt gcggcaggcg atccggcaca gcgcgaaagg
    10741 cggcgtgttc ctcgccgagg accggctctc gggggccagg gtcgtcgtca agcaggcgcg
    10801 cccgcacctc ggttccaccc tgcagggccg tgacgagtgc gaccagctcc gtcacgaggc
    10861 cgccatgctc gacctgttcg gcccgccggg gatcacggca cgcaaggtgg acctgttcga
    10921 gcagagcgac aacctgttcc tcgtacagga gcatctcgac gggaccatgc tcaccgcctg
    10981 ggccggcgag cgaaccggcc cggaccggcg ggggcacgac gaggtgctca ccgtggtgcg
    11041 cgggctgacc gccctggtcg cggccgtgca cgagcagggc tacgtgctgc gggacctcac
    11101 gcccaacaac gtcctcgtca ccgccgacgg cggctgccgc ctcgtcgacc tggagatggc
    11161 cgccatcccc ggcacgcccg tggcgagagc cttcactccg ggcttcgcgc cgcccgagca
    11221 gatgaacgcg cccaggcacg ctccggctcc cggcgtcgag gccgacctgt acgcgctcgg
    11281 ggccaccgtg ttcttcctga ccacgggctg cccgcccatg ctggcggacg acgggccgga
    11341 cgaggaacgg tcctggggcg accgggtgcg gacgctcgtg agcgtggcga cggcgggcga
    11401 tccggtggcc gaggcgttcg ctccgatgat ctcgggactg atgcgcgagg aacggtcgga
    11461 acgctgggat ctgcggcgcg tcgaggagtt cctcgccaaa ctggacgccg agccccggcc
    11521 gttcgtctcc gtgcggccgg tgcgccatct tggtgcggac gaaggggacc gcctgctgcg
    11581 ggacggggtc gcccacctgg tacggaccat ggcccggccg gcgcccggcg ggccggaccc
    11641 gctgcgcctg tggcccgtca ccgggttcgg ggccgacgcg gacccctgcg cggtgcagta
    11701 cggctcggcg ggggtcctga cggtgctggc gtccctgctc gacggtcctt tcgcccgcga
    11761 ccccggtctt ccggcgacat ggcggtccga cgtgaccggc gcgctcgcgg acgcggcggg
    11821 gtggacgctg cggcgcctcg accgcgagcc acggccctcc cccgggctct acttcgggcg
    11881 ggcgggcgtc gcctgggggc tgcacgaggc gggccgggtg ctcggtgacg acgacatgtg
    11941 cgccgccggc gtcgaactgg cgtccggact gccggacagc tggccgaacc ccgacgtgtg
    12001 ccacggcctg tcggggacgg ggctgacgct gctgcacttc tggcgggcca ccggggacgg
    12061 ccgcttccgc gacaaggccg gccgctgcgc cgacagtctg ctcgccgcgg ccgagcacac
    12121 ggccgggacg gtgctgtggc cgatccccgc gaccttcgcg tcgtcgctgg ccggagtcgt
    12181 gcactacggc ttcgcccacg gcgtcgccgg cgtgggggcc ttcctgctcg ccgccggcct
    12241 ggctctcggc cgcgacgact gcctggagac ggccacggcc ggtgggcgca cgctggtgga
    12301 ggcggccgag atcacggacg gcgccgcgtg gtgggaccag ggtccggccg gcggcgccag
    12361 gatgccgcac tggtgcaacg gctcctcggg cgtcggcacc ttcctgatcc ggctgcaccg
    12421 cgccaccggc gaccggcggt tcctcgacgc cgcccggggg gcggcgcgca ccgtccacct
    12481 gagccgggtc tcctcgggaa gctcccagtg tcacggcctg gccggcgacg ggcagttcct
    12541 gctcgacatg gccgacctgc tcggtgaacc ggcctaccac gaccaggccg gggaactggc
    12601 cgcgtacctg tgggcgcggg cggtgtcgcg cgacgggttg ctgctggtgc ccgacgagaa
    12661 cgggttcgag ctgagcgccg gctggaacac cggcctggca ggggtgctcg acttcctcca
    12721 ccggctgcgc cacggcgggc cccgctcctg gatggccgac gccggcgacg gggcggcccg
    12781 atgaccgccc ccgtcatcac cggcacggcc ggcgaggaga ccgcgcaccg ctcctccgag
    12841 acgcggcgga tcaacttccg gttctcccgg cgcgggcggt acgccgcctg cctgtccgcc
    12901 cgcggtcgtg gtcccctcgt cccggagctg tgggatctcg gcggcgggac tccggtgccc
    12961 atgacgctgg gccggccggc cggcgagagc tcctggagca cggtcgtccc gaccgacggc
    13021 ggcaggatcc tgctgggccg cgcccaggcg ggaggcgtac accgcctgct cctcatcacc
    13081 cccggcgagg cgccggcgcc gatgccggcc accttccacg gcggcggatt ccggctggtg
    13141 gccggcgggc cggagggagc cgccgccctg gccttccacg gcgccgggga gggccggacg
    13201 acggtgtggc gcgtgcccgc ggagcccggc cctctcgaag cggtcgccac cgtcccggcc
    13261 gtcctcggag ggggcgtctg gctcgacgcg tccggccggc gcctggccct gtcccgccac
    13321 ggggacgaac cgggcaccgt ggtactggat ctgccggacg gctcgctgtc gccgctgccg
    13381 ggcctggccg gcggtgagca cctcctgctc gcggccccgc ggggcggtgt cctgctcacg
    13441 acgctccgcc acgagggcgc ctatcgcctg ggcgtgcgcg gcaccgacga cggccccacg
    13501 gtcttccccc gcccgttgaa cgagatcgac ggcgcggtca caccgctggc gttcgatccg
    13561 gagggaaggc ggttggcgct tctggccacc cgcggagtcc gctcccacct gctcgtgtac
    13621 gacctgacga cggaggagat ccgggaggcc gcccttccgg ccggggcgct gtatccgagt
    13681 gcccactgga gcacggccgg cctgcacgtg atccacacga cgccggaccg gccctacgcc
    13741 ccgctgaccg tgctgaacgc gtccggtgcg cccgccaccc ggcgaggcgg tgagcgggcg
    13801 accgcccggg cgcagagcta cgacggtccc ggcggccgca tcgaggccgt ggtctacggt
    13861 gacccggccc ggagccggca ggtggtgctg gctctgcacg gtgggccgga ggccgcctgg
    13921 cagctctcct tcgatcctct cttccggcag atgtccgcgc gaggcatcgc cgtcgtcgca
    13981 cccaaccagc gcggaagcac cggctatggg gccgcgcacc gcgacgcgat ccgcggggcg
    14041 tggggcgggc ccgacctggc ggacatcctt cacctgggcc gcgtcgtcgg cgccggacgc
    14101 gggcccggcg cctgccgccc gatgctgtac ggcgccagct acggggcgta cctcgcgctc
    14161 ctggcggtcg ccgcggaccc gcacctgtgg tcgcgggccg ccgtggtcgc gccgttcctg
    14221 tcgggacggg agctctacac cgacggcccg gccacggtcc gggcgatgct cgaccgcctg
    14281 ggcggcctgg aggagatcac ggacgacgaa ctcggccccc gcgacctgct gcggctggcc
    14341 ggccgtctgc ggctcccgct tctcgtggtc cacggagaac acgacgacgt gattcccgtg
    14401 agccactccc ggcggctgcg cgaccggctc gccgaggtcg ccccgccagg cgccgaactc
    14461 acctacctgg aggtcaccgg cgcggggcac gacccgttga ccggccacgg cgcccatctc
    14521 gtccgtgacc gcctcgtcca cttcctggac accggctccg ctcagttgag ctgacgccgg
    14581 gagcaccgcc gtacgccagg ccgcgtacgg ccccgagacc ccgcaggctc gcccttcgca
    14641 tccgcggcga gcctgcggca ccaggagccg ccgcatgaca gagcggaggc ccggtacgaa
    14701 aggagaaccg catggaactc gacgtcaagg ccctggacat gctccccgcc tccgaggaga
    14761 gcgagctgta cccgtgccag atcacctgcg ccggaggcag gacctgcggc ggctggacct
    14821 gctggagcac cgactactga cccgtcagag gaaccggaaa caagcgccgc gaagcgcgaa
    14881 agacgaatca aggaggaact gtggaactcg acgtcaacgc cctggacatg cttcccgccc
    14941 ccgaggagag ccggctgatg gcgtgcaccg tcacctgcgg caggtcctgc tacggggcca
    15001 ccggcacctg tggcatcacc cagatctgag cacctgctga gcaggcgctc cgctcctgtc
    15061 cgctcacctg cctcggcagg acccgcggcg tgacggagcc gtccacgtga cggagccgcc
    15121 gcgagcgccc agggacggcc gtcctcggcc ggacgtccct gggcgcgaca tccctcccag
    15181 ctcgccccgc cgtgcccgac ggtgttcgcg gcggccgacc ggaaagagag tgagacgatg
    15241 cccggccccg ccccgagatc atccgaagag caggtgagcc acgggcacgg cgaccgtctc
    15301 atcgccgctc tgagccggga gacctggatg ccgctggccg cgaccgcgac cggctcgatc
    15361 gccacgaccg ccgtcgcgct ggccctgccc gcggcgctcg ccgccgccgt gaacgccgtc
    15421 gtcaccggcc ggggggcgct gacggcgacc gcgtacctcg cgctcctgct cgccggcgcc
    15481 gcgctggccg aggtcgccac cggaatcacg agcaccaccg cgacagcctc ggcgatcggt
    15541 acgctgcgcc tgcgtgtcgc cggtcacctc ctgtcggccg acgtctccgg cgccacccgc
    15601 ttctccaccg gtgagctcgt caaccgtctc gtgagcaaca cggcgacggc cgggtccgcg
    15661 ccggtgaccc tgctggggac gatcacgggc gtggccgcct ccgccggcgc cgtcgtcgcg
    15721 ctgttcgccg tcgacccgcg cgcgggcctc gccttcctcg ccgggacgcc cgtcctgatc
    15781 gtcgtgctgc gcgtgttcgt ctcccgcgtg tcggggctgt acgacgagta ccagagcgcg
    15841 cagggccgcc tggccgcccg cctcaccgag accctggccg gcatccgcac ggtcagggcc
    15901 gcgggcaccg cgaaccgcga gatcgaccgt gtgctccggc cgctggcgga cctctcctcc
    15961 accgggcacg ccctctggag ggcgcagtcg cgcaccgtgt ggcagatcat gctgctgatg
    16021 ccgctcgtgg agatcctcgt gctggcggtc gccgggctcg gcgtcgccga gggcaggctc
    16081 actccgggag cactcgtggc cgtggccgga tacgccgcgc tcgggctgac cttcgtcgag
    16141 cagatcgacc cgctgctggg cctggcctac ggccggtccg cggccgtccg ggtgctggag
    16201 gtgctcgcgc tgccggtcct gcccgcgggc cgccgccggt tgccggacgg cccgggggcg
    16261 ctgtccttcc gcggcgtgac cgtcacgcgg ggagacaccc gggtgctcga cgacatcgac
    16321 ctggagattc ccgccggggc gctgaccgcg gtcgtcggcc gctccggcgc cggcaagacc
    16381 actctcgcca tgctcgccgg gcggctgacg gagcccgacc acggccgggt gctgctcgac
    16441 gggcggcgcc tgagcgacct cgatccgggg tgcctgcgcg acgccgtggc ctacgcgttc
    16501 gaacgacccg ccctcctcgg cggggacatc gcctcggcca tcgcgtacgg cacggctcgg
    16561 acgacgcgcg aggccgtccg cgcggcggcg agggccgcgg aggtcgacga cgtggtctcc
    16621 cgtctccccc tcgggtacga caccccggcg gccggggcgc cgctgtccgg cggcgagatc
    16681 cagcggctcg ggctcgcccg cgcgttgctg cggcgggccc gcctgaccat cctcgacgac
    16741 gccaccagcg gcctcgacac cgtgaccgag gcgcaggtga cccgcaccct cgtggagggg
    16801 atgcgcggca ggacgcgcct ggtcgtcgcc catcgtccgg ccacggcggc cagggcggac
    16861 ctggtgatct ggctggaggc ggggcgggta cgcggccgcg gcacgcaccg ggagctgtgg
    16921 cggcaccggg actaccgcga cctcttcgcc ccggatgcgc tggattcccg cggggaaccg
    16981 caccgcggcg agcccgccgg ggtcgcctcg cggcaggagt cgtcgtgtcc gcggtgacca
    17041 ccgcccggcg gcagtccccg ccggcctctc ccccgcccgc cggcgatcgc gctcaggggc
    17101 cgtggcggct gctggcggcc ctgctgcgcc ggcgcccgcg ccccctcgcc ctggtcatgg
    17161 cctggtcggt cgtcgaggcg gctccggctc tgctgtccgg cctgctggtc gcgatggcgg
    17221 tcgaccgcgg cttccgcgcc gggcgccccg ggctgggcct cgtcctgctc ggcctgctgg
    17281 ccgcggcgat gctggtggga gcgatcgcga cccggctgat gttcccgcac ctcgccgcgg
    17341 tggtcgagcc tctccgcgac gacctcgtac gcgccgtggt cgaggcgacc gtgacccacg
    17401 cgtcggccgg tgagcaggcg cccgacggcg ccgccgtcaa ccgtctgacc gagcagatcg
    17461 agacggtccg cgccctgttg tcggcggtgc tgagaaacac ccggcaggtc ggggtcgccg
    17521 tggtcgccgc cgtcgcgggg ctcctgctgc tgtctccgct cgccgcggcc gtcgtcgccg
    17581 ggcccgtgct gatcgccgtg ttcgcgttcg tccggctgct gcgcctgctc gccgcgcgtc
    17641 agcgcgacct cctcctcgcc ggggagaggc tgacggccga ggtcactccc accctcgggg
    17701 ggctgcggga catcgcggcc tgcggggcga gggaccaggc gagggagtcg gtccggtcgc
    17761 tcgtgaccgc gcaggccgcg gcgatgcgcg cgctcgcgtg ggcgggcgcc aggcgacggc
    17821 tggtcgtcac gatcggcgcg cacgtgccca tggtcgcgct gctgctcgcg gccgggccgc
    17881 tgacggcgag cggccggctg accgccgggg agatcgtggg ggcgctgacc tatctgtcga
    17941 ccggcctcga gcccgccgtg cgcaccctcc tcggcaccgt cggctcctgg gggatcaccc
    18001 tggcggtgac cgcccagcgg ctcggcgacg tcgtgacgcc gcccccgccg cgggaggagc
    18061 ccgcgtgcgt cccggagacg ccggtcgccc acgacctccg gacggaccgc ctgaccttcg
    18121 cctactcgcc ccgggcggaa ccggtcgtac gggaactcga cctcacggtc ggcgaaggcg
    18181 agcacctggt cgtggtcggc ccgagcggca tcggcaagtc caccctggcc atgctgctct
    18241 ccgggctccg ccggcccacc gggggcgtgg tccggctcgg cgggctcgcg ctggacgcgg
    18301 tgccccggca gcacctgcac gaggccgtgg cgctggtgcc ccaggaggcg tacgtcttcg
    18361 ccgggacggt ccgcgagaac ctgggctatc tccgccccgc cggggaggcg gccgccgacg
    18421 agcggctcct cgcggcggcg gacgccgtcg gcgccgggcc gctgctcacg cggctgggcg
    18481 ggctcgacgg cgcgatcgac gaaccgtcca ccctgtccgc gggggaacgg cagctcgtca
    18541 ccctcgcgcg cgcgtatgcc tccccggcgc ggatcgtgat cctcgacgag gccacctgcc
    18601 acctcgaccc cgcaggcgaa gcacgggccg aggccgcctt cgcggccagg cgggggacgc
    18661 tcatcgtcat cgcccaccgc gtcagctcgg ccgcccgggc cgaccgcgtc ctgctcctgg
    18721 acggcgcgcg cgcgatcacc ggcacgcacc gcgacctcgt gacgcgctcg cctctctacg
    18781 ccgacctggt cggtcactgg aaccacgacg ccccgggacc ggaccgcctg ccggagtgat
    18841 cccggagtga tcttcgcgcc ccctcaggac agcacggaag gacctgcaca tgcgacaccc
    18901 cggacctacc gacatcatct gggacatcac gtacgcgtgc cccctgcgct gcacccactg
    18961 ctattcggag tcgggccggc ggcccgcgcg gcagctgggc cacgaggaca tgctcagggt
    19021 ggccgacgcg atcgtctccc tgggcccgcg ggcggtcgag ttcgcgggtg gcgagcccct
    19081 gctcgtcagg ggcgttcacg aggtggccga gcgcatctcc cgggccggtg tcgaggtcaa
    19141 tctctacacc agcgggtgga cggtgacacc ggcggcggcc gaggaggcgg cccgggtgtt
    19201 cacgaggatc acggtgagcg tcgacggagc cgacgccgcc acccacgacc ggatcagggg
    19261 cagggccggc tccttcgacc gcgcgatgaa cgcgctggcc ctcctcgacg acgtctcgcg
    19321 ccgccggacg gcccgcggcg acgcccccgt gatgttcgga gtcgactgcg cggtgatgcg
    19381 cggcaacttc gaccagatgg gcgacctctg cacgaccgtc acctcccggt tcgggcggat
    19441 ccggttcctc acgttcgggg ccgcggtgcc gtcggggctg gccagcaggc ccggcttcgg
    19501 cgacctggag ctcctcaccg gcgagcaggt ccggacgctc accagccccg agcaccacga
    19561 cacgctgcgg gcccgggttc cctcctcggt cgtggtgaac accaacgaca acgcgatgct
    19621 gctgatgcgg cccgaactcg tggagcgcta cggattcccc ctgctgcaga tcgagcccga
    19681 cggtgaggtg cgcgccatgc ccatctacga gggcaccgtc ggcagcctgc tgagcgagga
    19741 tccggcggtg ctgtgggaac gcgcggtcgc gcggtggagc gaccccttcg tcgtcgagac
    19801 cctttccgcg gtgcgcacct gggcggactg ggcggaggcg acccgccgca tcgactaccg
    19861 cttcggatcc gacgcggtca ggcggcgcat cgaccggcgg cccgactacg aggccacgcc
    19921 ggtctgacgt ccgccgcccg ccggccgtac cgccgggtca ggggatcagc ggggcgagcg
    19981 cctcgcggag cagcgcgccc gcgtcgccga ggacgtgccg cccgtccgtc acgacgcgcc
    20041 gcccgccgga caccaccgag tgcacgtcgg cggccgtcgc cgcgaagacc accgaggcga
    20101 ccgccgacgc ccgcgtcgcc cccgccgtgc ggaccgagtc gagccgtacg gagacgaggt
    20161 cggcccacgc gccgggcacc aggcaccccg cgtcggggaa gcccagggac gcctgcccgg
    20221 cggcggtggc ggcgtgcagg aggtcggcgg ccggccagtg gccgcgctcc cccgtgacca
    20281 gccgctcgtc cagctcgacc gcccgggcct cctcgaacag gtcgatgacg gcctggctgt
    20341 cgctgcccag cgtgacgggc gagccggcgt ccaggagccg gcgggcgggg ccgacgccgt
    20401 cggcgaggtc ccgctcggtg gtggggcaca tgcacacgtg gctggtcgac ccgcccagca
    20461 gcgccacgtc cacgtcggac aggtgcgtgg cgtgcaccgc ggtggagcgc ggcccgagcg
    20521 cgccgtggtc gtgcagcacc tgcaccggcg tcgcggcgta cgcctccacg cacgcctcgt
    20581 tctcggcccg ctgctcggac acgtgggcgt gcagcgggcc ggtgtgccgg tgggcgaagt
    20641 cgacgacgac gtgcatctgc tcggggggca ccgcgcgcac ggagtggatg gccgcgccga
    20701 tctccacatc ccgcgcgccc tcgtgggccc gcgccagcgc gtcggccctg gccgcccagc
    20761 gctcggcgtc cccgtcgccg aaccgcacct gggggccggc gagggcgtcg ccgatgccgc
    20821 cggtcaggta acaggtgtcc agcagggcga tgcgcagccc ggcccgcctg gccgcctcga
    20881 ccagcgcctc gcccatcgcg ttcgggtccg cgtacggcgt gcccccgggg ccgtgatgca
    20941 ggtagtggaa ctcggccact gcggtgatcc cggcgagcgc catctccgcg tacgtcgcgg
    21001 tggccagcgc gaggtagcgg tccgggtcga gcgcctcggc gaccgcgtac atccgctccc
    21061 gccagctcca gaagtcgccc cggcccgtct gggtgtggcc gcgcagcgcg cggtggaagg
    21121 cgtgcgagtg gcagttggcc aggccgggca gggtcagccc ggccagccgc tcggctcccg
    21181 gcggaggcgg cacgcccggc cggacgtccc cgatgcggga gccctcgatc gccaccgcca
    21241 cgctctccac gacctcgccg ggcggcagcc acgccatctc gcaccagtaa gtcacgtgca
    21301 ccggtcctcc aggtgggcgg catgacgggt ggcgtggcgg gcgccacggc cggtccggcg
    21361 ggccgtcagc gggtgggccc cgccgccggc cgcacggtga tctcggtgac gtgcgcgtcc
    21421 ggggtcgccg tcactgcggc cagtacggcg cgcgccaccg actccgcctc cagatacctt
    21481 cccggctcgt acggctcacc ctcctgctcg cgcacgtccc tttgcatgtc cgtgcccacc
    21541 cgcccgggga agatcgaggt gacccgtacg ccgttcggct gctcctcctc gcgcagcacg
    21601 tcgccgtagg cgcggagggc gaacttgctg gcggcgtagg agccccagtt ggggttggcc
    21661 cgctgccccg cgccggagtt gatcagcacg acgtgccccc gggccgcccg gagggcgggc
    21721 agcagcaacc gggtcagctc ggcgaccgcg acgacgttga cctccagcgt ccggcgccac
    21781 acctcggccg gggtgtcggc gaggtggccg agcctggcga tccccgcgct gtgcaccagc
    21841 aggtcgagcc gttcgatccc ctccacctcg gcgggggtca ggtcggtgag ctccaccgcc
    21901 cagggccggg acccgggcag ctcgtggcac aacgcgtcga gcgccgtgcc gtcccggccg
    21961 ccgagcagca ggtcgtgcgt gggggcgagg gcgcgggcga tcgccgcgcc gataccgcgc
    22021 gaagcgccgg tgatcaaagc cgtgggtcgc atgaagcact accttaggtc gccacgtcag
    22081 tcgccgccgt cccgccccgc gcgggggccg gcgtctgtgc ggacggcgct ggaacgcggc
    22141 ggggcgcccc ggcccactga ccggagcgcc ccgcctccgg cccggccacc gggcgcgccc
    22201 gcacgcgcgt agcccccggc gtccgggtcg gtggtgaagg agaggtaacg cacctcctgc
    22261 cttcccggct cccggtcgaa agaagctgtg gtcaggtgta agggctgctc acggttcccc
    22321 atcacccgcc cgcatgcctg cccgactcga ccgcccgcct cgcctgccct cgcgggcccg
    22381 ccggtcgtcc ggtcaggtcg cgacgaggaa ctgcgtggcg gcgagctccc ggtagagcgc
    22441 gtcggccgcg acgagctcgt cgtgggtgcc ccaggcccgc acgcgcccgg cctccatcac
    22501 cacgatccgg tcggccccgg tcacggtgga caggcggtgc gcgatcacca ggaccgtcgt
    22561 ctcccgcgca acctccgcca cgacctcccg caggcgcagc tcgttgacgg cgtcgagctg
    22621 ggacgtcgcc tcgtcgagca gcagcagcct cggccggcgc agcagcgccc tggcgatggc
    22681 cacccgctgc cgctcccctc ccgacagcag gaccccgcgg tgcccgaccg gcgtctccag
    22741 cccctcaggc agccgctcga ccaggtcgtc gaggcgggtg cggg
//
