LOCUS       NZ_VYTZ01000015        20933 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold15, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000015
VERSION     NZ_VYTZ01000015.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 195396)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 195396)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 90303
            Orig. end                         :: 111236
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000015.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..20933
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20933
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20933
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10933](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10933)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(22..>309)
                     /locus_tag="F5972_RS39515"
                     /pseudo=""
     CDS             complement(22..>309)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012762.5"
                     /locus_tag="F5972_RS39515"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="cellulose binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="YAVTSQWPGGFGATVTVTNTGTIATSGWTVAWTFPNGQTITQLWN
                     ASHTVNGSNVKATNLSWNGALGAGASASFGFNGSWNGANSNPSQVTCTAV"
     gene            242..607
                     /locus_tag="F5972_RS39520"
     CDS             242..607
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF046825.1"
                     /locus_tag="F5972_RS39520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_404803090.1"
                     /transl_table=11
                     /translation="MVPVFVTVTVAPKPPGHWLVTAYVAVHALPVLAEGEGDEEGLAEG
                     EGEGEGDGEGLGEGEGDGLCEGDGDGLGLGESEGEAEGDGLTEVPAFSAVQALTQASTA
                     FQLIATSLTDQALMSSR"
     misc_feature    252..272
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.34"
                     /tool="antismash"
     gene            complement(<547..2337)
                     /locus_tag="F5972_RS30675"
                     /old_locus_tag="F5972_30680"
                     /pseudo=""
     CDS             complement(<547..2337)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012961.5"
                     /locus_tag="F5972_RS30675"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30680"
                     /product="glycoside hydrolase family 9 protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MKKPGWTRRPRAALSLALAVGAASFAVVTATSPVHAVTRPPLGQN
                     IKVNQVAYAPGAAKQATVVNSSSSPLTWSLLNGSDQVVATGTTTVFGQDAPSGDTVHKI
                     DFSSYTGTGTNFVLTVGNESSRPFDIGADAWKKLPYDALAFFYHQRSGIAINGQYVGSQ
                     YARPAGHLNVSPNQGDNNVPCRTSCGYTLDVRGGWYDAGDHGKYVVNGGMSAWQLVNVY
                     ERAKYVSGADPAAFGDGTMAIPERGNGVPDILDEARWEIDFMLKMQVPDGRPLAGMAHA
                     KIHDQAWTGLPLRPDQDPQPRLLSAPTTAATLNLAASAAQCARVWASIDSAFSSRCLTA
                     AEKAYAAARANPSIIAPSSDDQGGGSYVDTKVTDEFYWAAAELYVTTGKQTYRDGLTGS
                     SLYYGKSFSNEGAQWSEVGSLGDITLALVPNGLTSTIGTQLRNRFVSNGDTLLTAMRNQ
                     GYPVPFAPSGGGYIWGSNNLILNNAALLALAYDFSGQERFRNGVFETMAYEFGRNPLGQ
                     SYVTGYGDQPSRNVHHRFWAHQLDSSLPIAPPGALAGGPNSGLQDPVAQERLGGCKPQR
                     CYLDDINAWSVNEVAINWNAV"
     misc_feature    2438..2458
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 20.58"
                     /tool="antismash"
     misc_feature    2449..2467
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.61"
                     /tool="antismash"
     misc_feature    complement(2452..2467)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.04"
                     /tool="antismash"
     misc_feature    2455..2470
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.15"
                     /tool="antismash"
     misc_feature    2456..2470
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 19.5"
                     /tool="antismash"
     gene            2508..3548
                     /locus_tag="F5972_RS30680"
                     /old_locus_tag="F5972_30685"
     CDS             2508..3548
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013153373.1"
                     /locus_tag="F5972_RS30680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30685"
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_204288001.1"
                     /transl_table=11
                     /translation="MTGTSLPTELGPRRRQEITVAQIARLAGVSPPTVSKVINGRPGVS
                     VATRRRIEELIREHGWQRRPERTESAAIVEVLFQALDSLWALELIRGVNEVAQSYGLTV
                     AVTDMHGHNSPHREWIEEVLARRPTGVIAVSAELSDHEYAQLASRSIPLVALDPHGEPS
                     HRVPSVGATNWNGGLSATRHLLELGHRRIAMINGPAALMCCRARLDGYRAAMETAGVPV
                     DPRFLRTGPLYVETGRTEARALFALPDRPTAVFAGNDLQALGVYQAALRAGLRVPDDLS
                     VVGFDDLPLAHWTDPPMTTVHQPLAKMGAAAAELVMAVSAGDTSEHHRIELATHLVVRG
                     STAPPA"
     gene            3675..4652
                     /locus_tag="F5972_RS30685"
                     /old_locus_tag="F5972_30690"
     CDS             3675..4652
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890496.1"
                     /locus_tag="F5972_RS30685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30690"
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_150938544.1"
                     /transl_table=11
                     /translation="MERWETAEKRAAEADGTPPAPRGARRRGWWLNAVGVALLGVMVAA
                     QIATGLRPDDLRLTTVVVVLIAASALAFASAATTPARAAGAFGAAVAAGYAAEWIGTRT
                     GLPFGDYHYTDVLWPRPGGVPLIVALAWGGMGLAAHAVATRAVPGRAVPAHAVATRAVP
                     GRAVPAHAVATRAAAGRAAAGRAAAARAVPYGVAGRVCLGAVALTAWDLFLDPQMLRLG
                     LWVWAEPGPYRGVPLGNFAGWLLVSLLVMTLIERIAHHPAPAAPGTAARAGATGLVALY
                     TVMAVMETVGFAVVFRPPDLLVAAAGGAAMGMCALLAWRGTWRK"
     gene            4640..6136
                     /locus_tag="F5972_RS30690"
                     /old_locus_tag="F5972_30695"
     CDS             4640..6136
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890495.1"
                     /locus_tag="F5972_RS30690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30695"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_225312040.1"
                     /sec_met_domain="DAO (E-value: 3.9e-11, bitscore: 36.5,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEVIVVGGGVGGMVAALLLARDGHDVRIHERLPRLGGKLAEHRR
                     DGFTFSIGPSLLTLPGLFLDLGIPLDLLELDELCRYRFADGSVLSTYRDPGRTAGEVDR
                     LAPGEGRHWRAYHRWAERCLDAAMRTFFVGPLTGPVVEPPAPWRGGQVPRARLGDLFAV
                     APGRTLDALAGGFFRDARLRQYVDRYATYAGSNPYRAPAALGCVPAIEHGDGGWYVRGG
                     LPRIADALAAALDKAGVEVRTETEVTEVIAGADRVHGVRTAGGEVTLADVVVVNADAAA
                     LYGRLLPDRTRLRRIAGLGLSSSAFLMLAAVEGRTEGMPHHSIVFSGDYRREFGDIFDR
                     RRPPEDPTVYIGCPSGHDATMAPDGAESWSMLVNVPAGDPARWPMPPEAYAELVLERLA
                     SRGHDLSGRLRFLDLLTPADLRDRYGAWGGAIYGGAYGGPFASFRRPGNRGPRRGLYLV
                     GGTAHPGGGLPLVAMGGRIVAELVARDLSRSGPRRGRARP"
     gene            6133..7470
                     /locus_tag="F5972_RS30695"
                     /old_locus_tag="F5972_30700"
     CDS             6133..7470
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546039.1"
                     /locus_tag="F5972_RS30695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30700"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_225312041.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.6e-25,
                     bitscore: 82.2, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGKGETVTTGRWVLGAAQAAAALVVLARLARGRRRLPPLSPPAA
                     RTETAGPDGREVAASESAARGGTQGGGTLSSEALSGEPQGGGTPGSGAPDRGARSGGTP
                     GGGGRGISVVIPARNEEHRLAPCLRAVLADPAVIEVIVVDDESSDGTARLAAAHGARVV
                     PGRPLPDGWVGKQWALHQGLREARGEIVMTLDADTRPRPGLCAALAAALDDHDLVSAGP
                     RFVCDGLAEQALHASFLATLVYRFGPIGPPAPPPPHRVMANGQCLAFRRAAMLRADGFA
                     RVRRHMTDDVALARALAADGWRVGFLDARDLLEVDMHESAAEVWREWGRSLPLGDVTRP
                     AWQAADLAVVWLAAALPVLRLAAGRPTRLDLGLLAVRLLLTTALRPAYARPGAGVALSL
                     LLDPATAVRLTQATLRPVRTWRDRSYPTMPVRDGGRPAPPARSGDR"
     gene            complement(7421..8083)
                     /locus_tag="F5972_RS30700"
                     /old_locus_tag="F5972_30705"
     CDS             complement(7421..8083)
                     /EC_number="2.3.1.275"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0043772 - acyl-phosphate
                     glycerol-3-phosphate acyltransferase activity [Evidence
                     IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546038.1"
                     /locus_tag="F5972_RS30700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30705"
                     /product="glycerol-3-phosphate acyltransferase"
                     /protein_id="WP_225312042.1"
                     /transl_table=11
                     /translation="MTTLPLLVPPAGSPPGPSFVSSFVPLLVAVIGGYLLGSIPVAVLV
                     AGRRGVDPREEGDRNPGFWNVRERLGARAAAPVFAGDMAKGVAAGLLGLVAGGAHTTAL
                     GVVAGPSVPLAYLAVGAAMLGHAWPVFAGFRGGRSVLTFAGGMAVICPPAFVPALAVLA
                     VTRLATRSFALGARAGVFALPVLQLAFAPIGHVAATGALMCLIGLRFGQAALAARRP"
     gene            8127..8969
                     /locus_tag="F5972_RS38495"
     CDS             8127..8969
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546037.1"
                     /locus_tag="F5972_RS38495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="spheroidene monooxygenase"
                     /protein_id="WP_225312043.1"
                     /transl_table=11
                     /translation="MAFDRPVLRRTPGLLFWRLLGTGRGPSTTLGADLRRWALLAVWRD
                     ERALEDFLERSPIPARWRREAVETWHVRLAPISSRGRWNGVEPFTPAPPLASAPLTPAP
                     FGPRIAEGLIQGTTPPGTEHQGTNLPALERLAPGKASSPVVSPVVSSGERAGGGPVAVL
                     TRASIRPSRLLAFYRSVPSVDRLLRAQEGCLASVGLGEWPLARQATFSVWRDAAAVRAF
                     AYAGRAHREVIERVRAHDWYSEELFARFVPYASAGTWDGTDPLAGLGPGSPGFALSHR"
     gene            complement(8971..9999)
                     /gene="plsX"
                     /locus_tag="F5972_RS30710"
                     /old_locus_tag="F5972_30715"
     CDS             complement(8971..9999)
                     /EC_number="2.3.1.274"
                     /GO_function="GO:0043811 - phosphate:acyl-[acyl carrier
                     protein] acyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0008610 - lipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="plsX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017556151.1"
                     /locus_tag="F5972_RS30710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30715"
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="WP_150938548.1"
                     /transl_table=11
                     /translation="MRDVPTASPPVVVDAMGGDHGPAEIVRGAVQARREHGVPVVLAGR
                     AGVVRAELARLGAVGEIDVAHADDVVPMTERGAGAIRMARSSLAVGLGLVRDGAGAAFV
                     SAGSTGAVAACAVDRLGTAPDILRPALAVALPTTAGGATVLIDAGATVDPTPEMLAQFA
                     LLGASYARLVLGVADPRVGLLSIGAEPGKGNRLTRRAEALLRDLPLRFHGPVEGGDVLT
                     GVADVIVTDGFTGNVVLKNVEGTVRATLALLATEVGSSGVGDGAGTRDAAGAEALRRVA
                     GRYDPETHGGAALLGLTGTVVVAHGSSRARTIARACVVAHDLARGEVVARLGDRPAVRP
                     AR"
     gene            complement(10001..10933)
                     /locus_tag="F5972_RS30715"
                     /old_locus_tag="F5972_30720"
     CDS             complement(10001..10933)
                     /EC_number="2.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011293493.1"
                     /locus_tag="F5972_RS30715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30720"
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_150938550.1"
                     /sec_met_domain="phytoene_synt (E-value: 3.1e-96, bitscore:
                     315.1, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.7e-66,
                     bitscore: 217.9, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTSPPPSSAPSSATLTAAYERCRRLHARYGRSYYLATLLLPAWK
                     RPHVHALYGFARYADEIVDSFSMGGDRSRALERLASRLTAALGGEPVRDPVLPAFAHTV
                     RAFGIDHADVAAFLASMRADLTVRRYATYDDLLGYMEGSAAAIGTMMLPVLEPLPGEDE
                     RAREPARQLGLGFQLTNFVRDVREDLARGRIYLPLADLDKFGVTPADLAAPRATPAVRD
                     LVALNCERARDHYRRAWEGIALLAPSSRPCIRAAYELYGGILDEITAAGHDVLARRATV
                     PRGRRLAIFTRNLLAARAAAQAERRVGVA"
     gene            complement(10930..12570)
                     /gene="crtI"
                     /locus_tag="F5972_RS30720"
                     /old_locus_tag="F5972_30725"
     CDS             complement(10930..12570)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020546035.1"
                     /locus_tag="F5972_RS30720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30725"
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_225312044.1"
                     /sec_met_domain="DAO (E-value: 4.3e-11, bitscore: 36.3,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQPPEREGAKTLLTAPPITETAADRRTGRDHRNDRRSSAHDDDDP
                     QDRLMAAGGPVVVVGAGLGGLAAAMRLAGTGREVIVVEAADVPGGCCGTAVLGEHRVDT
                     GPSVLTMPGVLADTFAAAGQDMERWLPLRRLDPYYRLTFHDGSRLDVVAGADAMEDQVR
                     ALCGPAEAARYRRFRGLLGEMFAAEWDAFIDSDMTRLRALARPYALARLTALGGFRRLD
                     RLVRRHLTDERLIRAHTFQSLYVGRSPQRALGVYAVIAHMDTVGGVYFPREGGMHAVPR
                     AMAAAAEKAGAVFRYGVRATRIETDGAGVRAVRLDTGERIAARHAVVACDLVGAHGAGG
                     DGLLPEEAADWRLRRPRFSPSCLVAHFALDRRPDGQAHHTLHFGREWRATFAALEAGAP
                     QPDPSLLVTCPEYHGPDDHGPGGAGPAVLSVLEPTANLTGGAGWAALTPRLVNRMLDRL
                     SGLGYGDLSATPRLVFDPPAWRRRGHSAGTPFALDARFTQTAWFRPSGAARRVPGLHFA
                     GMYTAPGVGVPPVLISGRLAAERILESTP"
     gene            12803..13960
                     /locus_tag="F5972_RS30725"
                     /old_locus_tag="F5972_30730"
     CDS             12803..13960
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888349.1"
                     /locus_tag="F5972_RS30725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30730"
                     /product="MerR family transcriptional regulator"
                     /protein_id="WP_404803088.1"
                     /transl_table=11
                     /translation="MRRDGQPGTDGDAVSEEEPGYGIGAVARRLGVPASTLRTWNLRYG
                     IGPSRRSPGGHRRYDEADLRRLQEMNRLVRSGMPPADAANLALRQRPAAAGERSTGEPA
                     AGEPRTGRARTAEQGAAEQAAFPAGGVAAAPGRPAPRPARGLTGGPAGSAAPPESGLTS
                     PSTSAREVTPRVAPELPAAEPGLLSAAMLARVVAAMDAPAVSVALDAALAAHGVLWTWE
                     RLVLPVFAAISRRQQETGAGIDIEHLFSNRLQAALVRFAAHAPAPVHPRPVLLAAAEEE
                     QHTLAIQALAAALGGLAVETRVLGARTPYSALADAMRRVGPAAVFVWSQTPETGDPAPL
                     GGLPGLRPACRIIAGGPGWGDGVPTEVVRVTTFRDAISAVMTTLR"
     misc_feature    complement(14045..14056)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.34"
                     /tool="antismash"
     gene            14073..14591
                     /locus_tag="F5972_RS30730"
                     /old_locus_tag="F5972_30735"
     CDS             14073..14591
                     /GO_function="GO:0016987 - sigma factor activity [Evidence
                     IEA]"
                     /GO_process="GO:0006352 - DNA-templated transcription
                     initiation [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888348.1"
                     /locus_tag="F5972_RS30730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30735"
                     /product="RNA polymerase sigma factor"
                     /protein_id="WP_150938554.1"
                     /transl_table=11
                     /translation="METTLEFRLAAGDTGALGECYREHSPAVRSYLRKLVPPQDVEDVL
                     QVVFTEVWRFRHRFDPGRSLAAWLFGIAHNRAVDHLRARTPTTVPLEAVPDPAGHDGRR
                     DGDELADRDRVLRALAALPQVQRQAIELAYYGDLTQREIAEHLRVPLGTVKARTARGLH
                     RLSALLEAA"
     misc_feature    14597..14615
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 20.65"
                     /tool="antismash"
     gene            14597..15604
                     /locus_tag="F5972_RS30735"
                     /old_locus_tag="F5972_30740"
     CDS             14597..15604
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017613081.1"
                     /locus_tag="F5972_RS30735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30740"
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="WP_225312052.1"
                     /transl_table=11
                     /translation="MENATESTTESTMESMTAEVRPRVAVSSCLLGAPVRFNGGHSRDR
                     FLAGELDEHVDWVPICPEMEIGLGAPRETLRLEGGPDGPRLLTRRTRRDLTAEMADLAA
                     DRAAEIGAVDGYVFKSKSPSCGLHGVPVYGGSAPGAPGRRGPGLFASAVTDAHPSLVVE
                     DEGRLHDAVLREAFVERIFAAARLRALLSGDWRPRDLVDFHARHKMQILAHSPGAYRVI
                     GRLVAAAGDLPREALAREYGWAFRTALLVRATIGRHVNVLHHFLGRISADLDPVRRADL
                     TEVIEAYRAHRVALAVPLALLRHHAKGAGAGQVQEQTYLSPYPDALRLRNHVPA"
     gene            15658..16143
                     /locus_tag="F5972_RS30740"
                     /old_locus_tag="F5972_30745"
     CDS             15658..16143
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015060.5"
                     /locus_tag="F5972_RS30740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30745"
                     /product="TspO/MBR family protein"
                     /protein_id="WP_150938556.1"
                     /transl_table=11
                     /translation="MGRTSKKTLTCTALAVTAAAVAGGLGTDPRSSWYHRLRKPSWQPP
                     RQAYGLVWTPLYATIAYASARALSLGDERSRPALRRALAANLALNAAWPPLFFKARSPR
                     IALAELVALNASNVLLTRRFLRQDRAAGLLLLPYTGWTLFATALNASIARRNPPEKA"
     gene            complement(16190..16699)
                     /locus_tag="F5972_RS30745"
                     /old_locus_tag="F5972_30750"
     CDS             complement(16190..16699)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017534457.1"
                     /locus_tag="F5972_RS30745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30750"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_150938559.1"
                     /transl_table=11
                     /translation="MSGTRWLDDEEQRTWRAYIRTSQLLQDALERQLQRDSGIPHAYYM
                     IIVVLSESPGRTMTMSELSSILRYSVSRLSHAVSRLEEKGWVRRVKRPEDRRTTVAELT
                     DEGFAALVEAAPGHVEEVRRVLFDPLTTTQVRRFREVLTTILTALESQEPPDEAERSPQ
                     LDPAAQ"
     misc_feature    complement(16601..16603)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            16785..19088
                     /locus_tag="F5972_RS30750"
                     /old_locus_tag="F5972_30755"
     CDS             16785..19088
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622636.1"
                     /locus_tag="F5972_RS30750"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30755"
                     /product="phosphoketolase"
                     /protein_id="WP_404803089.1"
                     /transl_table=11
                     /translation="MDEMERIDAYWRAANYLSVGQIYLMDNPLLTEPLSAEHVKPRLLG
                     HWGTTPGLNFCFAHLNRVIRERDQEMIYIAGPGHGGPAAVAHAWLEGTYTERYPHITRD
                     ATGMRRLFRQFSFPGGIPSHVAPETPGSIHEGGELGYALSHAYGAAFDNPRLVVACVVG
                     DGEAETGPLATAWHSNKFLNRGGDGVVLPILHLNGYKIANPTVLARIPEPELLKLFEGY
                     GYRPHIVSGHEPAEMHELMAGTLDTVFDQMADGGPLPMIILRTPKGWTGPREVDGLPVE
                     GTWRAHQVPLTDVRDRPDRLETLREWMLSYRPEELFDADGRPVEAVTATVPDGPLRMSA
                     SPHANGGELLRPLVLPDFRDYAVEVKSPATASTEPTRVLGGFLRDVIAANPENFRLLGP
                     DETASNRLSAVFEATGKEWEAALLPTDENLGPAGRVMEVLSEHQCQGWLEGYLLTGRHG
                     LFNCYEAFIHIVDAMFNQHAKWLESSRKIPWRRPVASLNYLLSSHVWRQDHNGFSHQDP
                     GFLDVVVNKKAEVVRVYLPPDANTLLSTADHCLRSRDYVNVVVAGKQPVLDLMSMDEAA
                     VHCARGLGILEWASTDEGAHPDVVLACAGDVPTLETLAAAAMLREHLPELKVRVVNVVD
                     LMRLQPASEHPHGLPDVEFDALFTTDRPIIFNFHGYPWLIHRLTYRRTGHENLHVRGYK
                     EEGTTTTPFDMAMLNDIDRYHLVMDVIDRVPGLGSTAAHLRQRMADARLRARAYTREYG
                     EDPAEIRDWTWPAS"
     gene            19287..19766
                     /locus_tag="F5972_RS30755"
                     /old_locus_tag="F5972_30760"
     CDS             19287..19766
                     /EC_number="3.6.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012514.5"
                     /locus_tag="F5972_RS30755"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_30760"
                     /product="NUDIX hydrolase"
                     /protein_id="WP_150938563.1"
                     /transl_table=11
                     /translation="MTPEGYGRSPARHPSASALLITDEASRALLVRPTYKDGWEFPGGA
                     VDPGETPWEAAVREAGEELGITCRMPPVLLCADWMRPRGHDLGGFRLVFDGGVMTAGEL
                     AEIRLPVEELSDWTLADPADAAAYLPPERVRRLRAAVQARAAGRMAYLEDGHPVT"
     gene            complement(20102..20359)
                     /locus_tag="F5972_RS30760"
                     /old_locus_tag="F5972_30765"
     CDS             complement(20102..20359)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS30760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_30765"
                     /product="hypothetical protein"
                     /protein_id="WP_150938565.1"
                     /transl_table=11
                     /translation="MNLGSSGCTTANIPASGAHEIAYYVEGGFLCAQADFQIIDAGNGV
                     VVYHRHVGSGTVSGTVGGLYGSYYLRIYWSCGGASGKLHN"
     misc_feature    complement(20344..20358)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.1"
                     /tool="antismash"
     misc_feature    20456..20470
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.67"
                     /tool="antismash"
     misc_feature    complement(20489..20505)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.08"
                     /tool="antismash"
     misc_feature    complement(20497..20510)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 13.08"
                     /tool="antismash"
ORIGIN
        1 gccgcgcggg gcccgtgctc gtcagacggc cgtgcaggtc acctgggacg gattcgagtt
       61 ggcgccgttc caggagccgt tgaagccgaa cgaggcggag gcgccggcgc cgagcgcgcc
      121 gttccaggac aggttcgtag ccttcacgtt cgatccgttc accgtgtgcg aggcgttcca
      181 gagctgggtg atcgtctggc cgttggggaa ggtccaggcg accgtccatc cgctggtggc
      241 gatggtgccg gtgttcgtca cggtgacggt cgccccgaag ccgccgggcc actggctggt
      301 gacggcgtac gtcgcggtgc acgccttgcc ggtgctcgcc gagggtgaag gggacgagga
      361 ggggctcgcc gaaggcgaag gcgaaggcga aggcgacggg gagggactcg gcgaaggaga
      421 gggggacggg ctctgtgagg gggacggtga cgggctgggg ctgggcgaat ccgaggggga
      481 agccgagggc gacgggctca cggaggtgcc ggccttctcc gcggtccagg cactcaccca
      541 ggccagcacc gcgttccagt tgatcgcgac ctcgttgacc gaccaggcgt tgatgtcgtc
      601 caggtagcac ctctgcggct tgcacccgcc gagcctctcc tgggcgaccg ggtcctgcag
      661 cccgctgttg gggccgccgg ccagcgcgcc gggtggcgcg atcggcagcg acgagtcgag
      721 ctggtgggcc cagaaccggt ggtggacatt gcgcgagggc tggtcgccgt acccggtcac
      781 gtacgactgg cccagcgggt tgcggccgaa ctcgtaggcc atcgtctcga acaccccgtt
      841 gcggaagcgt tcctgcccgc tgaagtcgta ggcgagcgcg agcagcgcgg cgttgttgag
      901 gatgaggttg ttcgagcccc agatgtagcc tccgccggac ggtgcgaacg ggacggggta
      961 gccctggttg cgcatcgcgg tgagcaacgt gtcaccgttg ctcacgaaac ggttgcgcag
     1021 ttgcgtcccg atcgtggagg tcaggccgtt cgggacgagc gcgagcgtga tgtcgccgag
     1081 cgagccgacc tccgaccact gggcgccctc gttggagaag ctcttgccgt agtagaggga
     1141 cgagccggtg aggccgtcgc ggtaggtctg cttgcccgtg gtgacgtaca gctcggcggc
     1201 cgcccagtag aactcgtcgg tcaccttggt gtcgacgtac gagccgccgc cctggtcgtc
     1261 gctgctcggg gcgatgatgg acgggttggc cctggccgcc gcgtacgcct tctcggcggc
     1321 ggtgaggcag cggctggaga aggccgagtc gatggaggcc cacacgcggg cgcactgcgc
     1381 ggccgacgcg gcgaggttca gcgtggcggc ggtggtgggc gccgacaaca gccggggctg
     1441 ggggtcctgg tcgggccgca gcggcaggcc ggtccacgcc tggtcgtgga tcttggcgtg
     1501 tgccatgccc gccagcggcc tcccgtccgg gacctgcatc ttcagcatga agtcgatctc
     1561 ccagcgggcc tcgtcgagga tgtcgggcac gccgttgccc cgctccggga tggccatggt
     1621 gccgtcgccg aaggccgcgg gatcggcgcc ggagacatac ttggcccgct cgtagacgtt
     1681 gacgagctgc cacgccgaca tgccgccgtt caccacgtac ttgccgtggt cgccggcgtc
     1741 gtaccagccg ccgcggacgt ccagggtgta cccgcagctc gtgcggcagg gcacgttgtt
     1801 gtcgccctgg ttgggcgaga cgttcaggtg cccggcgggc cgggcgtact ggcttcccac
     1861 gtactgaccg ttgatcgcga tgccgctgcg ctggtggtag aagaacgcga gcgcgtcgta
     1921 cggcagcttc ttccaggcgt ccgcgccgat gtcgaagggc cggctggact cgttgcccac
     1981 ggtgagcacg aagttcgtgc ccgtcccggt gtacgaagag aagtcaattt tgtgaacggt
     2041 gtcgcccgac ggcgcgtcct gcccgaaaac ggtcgtggtc ccggtcgcca ccacctggtc
     2101 ggagccattg agcaggctcc acgtcagcgg cgaggaggag gagttgacga cggtcgcctg
     2161 ctttgccgcg cccggcgcgt aggcgacctg gttgaccttg atgttctgcc cgagcggcgg
     2221 tcgcgtgacg gcgtgcaccg ggctcgtcgc ggtcacgacg gcgaacgacg ccgcgccgac
     2281 ggcaagcgcc agggacagcg ccgcgcgtgg gcgacgtgtc catcctggct tcttcatgat
     2341 taacacctcc ggcgtttatg tttcgtgacc gcatcatgag ggggagacgt ggccgtgaga
     2401 cattcctcag tcatcacgcg tttcgcaccc gcaggtcatc gcatcgggct gacgaatgat
     2461 tctgaatatt tcacgaacgc tttcgcggac tctctaaact ttcgcgtgtg accggcacaa
     2521 gccttcccac cgagctagga ccgcggcgcc gccaggagat cacggtcgcg cagatcgcca
     2581 ggctggccgg ggtgtccccg ccgaccgtgt ccaaggtgat caacggacgc cccggcgtgt
     2641 cggtcgccac ccggcgccgg atcgaggaac tgatccgcga gcacggctgg cagcgcaggc
     2701 cggagaggac cgagtccgcg gccatcgtcg aggtcctctt ccaggctctc gacagcctgt
     2761 gggcgctgga gctcatccgt ggtgtcaacg aggtcgccca gtcctacggc ctgaccgtgg
     2821 ccgtcaccga catgcacggg cacaactccc cgcaccgcga gtggatcgag gaggtcctgg
     2881 cccggcgccc caccggtgtg atcgccgtct ccgccgagct gagcgaccac gagtacgcgc
     2941 agctcgccag caggtccatc ccgctcgtcg cgctcgaccc gcatggcgag ccaagccatc
     3001 gcgtcccctc ggtcggcgcg acgaactgga acggcggcct gtcggccacc cgccacctgc
     3061 tggagctcgg gcaccgcagg atcgcgatga tcaacggccc ggcggcgctg atgtgctgcc
     3121 gcgcccggct cgacggctac cgcgcggcca tggagaccgc gggcgtgccc gtcgaccccc
     3181 ggttcctgcg gaccggcccg ctctacgtgg agaccggccg taccgaggcg cgggcgctgt
     3241 tcgccctccc cgaccggccc accgccgtct tcgccggcaa cgatctgcag gcactcgggg
     3301 tctaccaggc ggccctgcgg gccgggctgc gcgtgcccga cgacctcagc gtcgtcggct
     3361 tcgacgacct gccgctcgcc cactggacgg acccgccgat gaccaccgtc catcagccgc
     3421 tggccaagat gggcgccgcc gccgcggagc tcgtcatggc cgtcagcgcg ggcgacacgt
     3481 ccgaacacca ccgcatcgag ctcgccaccc acctggtcgt acgcgggagc accgccccac
     3541 cggcctgacc ggcggcgggc ccgaagcgcc gcccaggcgt cggaatcctt cgggtcgtcg
     3601 gcgatcgagg cggtgatatg aggatgtgcc cgcccggggc atccggtcgc cggcgtccga
     3661 tcgaatgacc gtacgtggag agatgggaga ccgctgagaa acgggcggcc gaggcggacg
     3721 gcacgccccc cgcgccgcgc ggcgcccgca gacgcgggtg gtggctgaac gccgtcggcg
     3781 tcgcgctgct gggcgtcatg gtggccgcgc agatcgcgac cgggctgcgg cctgacgacc
     3841 tgcgcctgac caccgtggtc gtggtgctga tcgcggcgag cgcgctcgcc ttcgcgtccg
     3901 cggccacgac cccagctagg gcggcgggcg cgttcggggc ggcggtggcg gcgggttacg
     3961 ccgccgagtg gatcggcacg aggacgggcc tgcccttcgg cgactaccac tacaccgatg
     4021 tgctgtggcc gcggcccggt ggcgtcccgc tgatcgtcgc cctcgcgtgg ggcggcatgg
     4081 gcctggccgc ccacgccgtc gccacccgtg ccgtccccgg acgcgccgtc cccgcccacg
     4141 ccgtcgccac ccgtgccgtc cccggacgcg ccgtccccgc ccacgccgtc gccacccgtg
     4201 ctgccgcggg tcgtgccgcg gccggtcgtg ctgccgccgc ccgggccgtg ccgtacggcg
     4261 tggcgggccg ggtttgcctc ggggccgtcg cgctcaccgc gtgggacctc ttcctcgacc
     4321 cccagatgct caggctcggg ctgtgggtct gggccgagcc cgggccgtac cgcggtgtgc
     4381 cgctcggtaa cttcgccggg tggctgctgg tctcgctcct ggtcatgacg ttgatcgaac
     4441 gcatcgcgca ccaccccgcc ccggcggcgc cggggacggc ggcccgggcg ggggccaccg
     4501 ggctggtcgc cctctacacg gtgatggcgg tgatggagac cgtcggcttc gccgtggtct
     4561 tccggccgcc cgacctgctg gtggccgccg ccggaggggc cgcgatgggt atgtgcgcgc
     4621 tgctcgcctg gaggggcaca tggcggaagt gatcgtggtc ggtggcggcg tcggcggcat
     4681 ggtggccgcc ctgctgctcg cgcgggacgg gcacgacgtg cggatccacg agcggctgcc
     4741 caggctcggc ggcaagctgg ccgagcacag gcgcgacggc ttcacgttct cgatcggacc
     4801 ctcgctgctc acgctgcccg gcctcttcct ggacctcggc atcccgctcg acctgctcga
     4861 actcgacgag ctgtgccggt accgcttcgc ggacggctcg gtgctgtcca cctaccgcga
     4921 cccgggccgt acggccgggg aggtggaccg gctcgcgccg ggcgagggcc gccactggcg
     4981 ggcctaccac cgctgggccg agcgctgcct ggacgccgcg atgcgcacct tcttcgtggg
     5041 gccgctcacc gggcccgtcg tcgagccacc ggccccctgg cggggcgggc aggttccgcg
     5101 ggcacggctg ggtgacctgt tcgcggtcgc gcccggccgc accctggacg cgctggcggg
     5161 cggtttcttc cgggacgccc gcctgcgcca gtacgtggac cgctacgcga cctacgcggg
     5221 atcgaacccc taccgcgcgc ccgccgccct cggctgcgtc cccgcgatcg agcacggcga
     5281 cggcgggtgg tacgtccggg gcggcctgcc ccgcatcgcc gacgcgctgg ccgcggcact
     5341 cgacaaggcg ggcgtggagg tccgtacgga gaccgaggtc accgaggtga tcgcgggcgc
     5401 ggaccgggtt cacggcgtcc gtacggccgg aggcgaggtg actctcgccg acgtcgtggt
     5461 cgtcaacgcc gacgcggccg cgctctacgg gcggctgctg cccgaccgca cccggctgcg
     5521 ccggatcgcc gggctgggcc tgtcctcgtc cgccttcctg atgctcgccg ccgtcgaggg
     5581 ccgcacggag ggcatgcccc accactcgat cgtgttctcc ggcgactacc ggcgggagtt
     5641 cggcgacatc ttcgaccggc gacggccgcc ggaggacccc acggtctaca tcggctgccc
     5701 gtccgggcac gacgccacga tggcgcccga cggcgcggaa agctggagca tgctggtgaa
     5761 cgtcccggcc ggcgacccgg cccgatggcc gatgccgccc gaggcgtacg cggaactcgt
     5821 cctggagcgc ctggcgagcc gggggcacga cctgtccggg cggctgcgct tcctcgacct
     5881 gctgaccccg gccgacctgc gggaccggta cggcgcctgg ggcggggcga tctacggcgg
     5941 ggcgtacgga ggcccgttcg cctccttccg ccgtcccggc aaccgggggc cccggcgggg
     6001 cctctacctc gtcggcggga ccgcgcaccc cgggggcggc ctgccgctgg tggcgatggg
     6061 cgggcgcatc gtggccgaac tcgtggcccg cgacctctcc cgttccggcc cgcggcgggg
     6121 aagggcgaga ccgtgacggg gaagggcgag accgtgacga ccggccggtg ggtgctcggg
     6181 gccgcccagg cggcggccgc cctcgtggtg ctggcgcggc tcgcccgcgg acgccggcgc
     6241 ctgcccccgc tcagcccgcc cgccgcgcgc acggaaacgg cgggccccga cggccgggaa
     6301 gtcgccgcat cagaatcggc cgcccgcggc gggacacagg gcggcgggac gctgagcagc
     6361 gaggcactga gcggcgagcc acaaggcggc gggacacccg gcagtggggc gccggatcgc
     6421 ggggcacgga gcggcgggac gccgggcggt gggggcaggg gaatatcggt ggtgatcccg
     6481 gcgaggaacg aggagcaccg cctcgcgccc tgcctgcgcg cggtgctggc cgaccccgcc
     6541 gtcatcgagg tgatcgtggt ggacgacgag tcctccgacg gcacggcccg gctcgccgcc
     6601 gcgcacggcg cgcgcgtggt gccgggacgg ccgcttccgg acggctgggt gggcaagcag
     6661 tgggcgctgc accaggggct gcgggaggcg cgcggcgaga tcgtcatgac cctcgacgcc
     6721 gacacgcggc cccggcccgg cctgtgcgcg gcgctggccg ccgcgctgga cgaccacgac
     6781 ctggtcagcg ccggtccgcg cttcgtctgc gacggactcg ccgagcaggc gctgcacgcc
     6841 tcgttcctcg ccacgctggt gtaccggttc ggcccgatcg gtcctccggc cccgccgccc
     6901 ccgcatcggg tcatggccaa cggccagtgc ctggccttcc gccgtgcggc gatgctccgg
     6961 gccgacggct tcgcccgggt gcggcggcac atgaccgacg acgtcgccct ggccagggcg
     7021 ctcgcggcgg acggctggag agtcggcttc ctcgacgccc gggatctgct ggaggtcgac
     7081 atgcacgagt cggccgccga ggtgtggcgg gaatggggac ggtcgctgcc gctgggcgac
     7141 gtcacccgcc ccgcctggca ggccgccgac ctcgccgtcg tctggctcgc cgccgcgctg
     7201 ccggtgctcc gcctggccgc cggacggccg acccggctcg atctcgggct gctcgccgtg
     7261 cgactgctgc tcacaacggc cctgcgaccg gcctacgccc ggccgggggc gggcgtggcg
     7321 ctgtcgttgc tgctcgaccc ggcgaccgcc gtacggctga cgcaggcgac gctgcggccc
     7381 gtgcgcacct ggcgcgaccg ctcctacccc accatgccgg tcagggacgg cgggcggcca
     7441 gcgccgcctg cccgaagcgg agaccgatga ggcacatcag cgcgccggtc gcggcgacgt
     7501 gcccgatcgg cgcgaaggcc agttgcagca ccgggagcgc gaacaccccg gccctggctc
     7561 ccagcgcgaa cgacctggtg gccagccgcg tcaccgccag gacggcgagc gccggcacga
     7621 acgcgggcgg gcagatcacg gccatccccc cggcgaaggt cagcaccgac cgcccgccgc
     7681 ggaacccggc gaagaccggc cacgcgtggc cgagcatcgc cgctcccacc gcgaggtacg
     7741 ccaggggaac gctcggcccg gcgaccactc ccagtgccgt cgtgtgggcg cccccggcca
     7801 ccaggccgag cagcccggcg gccacgccct tcgccatgtc cccggcgaag acgggcgccg
     7861 ccgcccgcgc cccgagccgt tcgcgcacgt tccagaagcc ggggttgcgg tcgccctcct
     7921 cacggggatc gacgccgcgc cgcccggcca ccagcaccgc caccgggatc gagccgagaa
     7981 ggtagccacc gatgaccgcg acgagcagcg gaacgaacga ggaaacgaac gaggggcccg
     8041 gcggggaacc ggctgggggg acgagcagcg ggagcgtcgt cacgttccac ctccacaggt
     8101 acgcggatcg gggggcgatg cgccacatgg ccttcgaccg tccggtgctg cgccggaccc
     8161 cgggactgct gttctggcgg ctgctcggca cgggccgggg gccgtccacg acgctcggcg
     8221 ccgacctgcg ccgctgggcg ctgctggccg tgtggcggga cgagcgggcg ctggaggatt
     8281 tcctggagcg ctcgccgatc ccggcgcgct ggcggcgcga ggccgtcgag acctggcacg
     8341 tacggctcgc gccgatctcc tcgcgcggcc gctggaacgg cgtcgaaccc ttcacccccg
     8401 cgccgccgct cgcctccgcg ccgctcactc ccgcgccctt cggccctcgg atcgcggagg
     8461 gcctgatcca gggcacgacg ccgccgggca cggaacatca ggggacgaac ctcccagccc
     8521 tggagcgcct cgcgccggga aaggcgtcct cgccggtggt gtctccagtg gtgtcttcgg
     8581 gggagcgggc gggcggcggg ccggtggcgg tgctgacccg ggcgtcgatc aggccgtcgc
     8641 ggctcctggc gttctaccgg tccgtcccct ccgtcgaccg gctcctgcgc gcgcaggagg
     8701 gctgcctcgc ctcggtcggc ctgggggagt ggccgctggc gcggcaggcc accttctccg
     8761 tgtggcgtga cgccgccgcc gtccgcgcgt tcgcctacgc gggacgcgcg caccgcgagg
     8821 tgatcgagcg cgtccgcgcg cacgactggt actccgagga actgttcgcc cggttcgtgc
     8881 cgtacgcgag cgcgggcacc tgggacggga ccgatcccct cgccggtctt ggccccggtt
     8941 cgcccgggtt cgccctgtcc caccgctgac tcaacgggcg gggcggacgg cgggacgatc
     9001 gcccaggcgg gccacgacct cgccccgggc caggtcgtgg gccacgacgc aggcccgcgc
     9061 gatggtccgg gcccgcgagg agccgtgggc caccacgacg gtgccggtca ggcccagcag
     9121 cgccgcgccg ccgtgcgtct cagggtcgta gcggccggcc acccgccgca gcgcctcggc
     9181 gccggccgcg tcccgcgtgc ccgccccgtc acccacccca ctgctgccca cttccgtggc
     9241 cagcagggcg agcgtcgccc gtacggtgcc ctcgacgttc ttcagcacga cgttgccggt
     9301 gaagccgtcg gtcacgatca catcggccac cccggtgagc acgtcgccgc cctcgaccgg
     9361 cccgtggaag cgcagcggca ggtcgcgcag cagggcctcg gcccggcggg tcaggcggtt
     9421 tcccttgccg ggctcggcgc cgatcgacag caacccgacg cggggatcgg ccacgcccag
     9481 cacgagccgc gcgtacgacg ccccgagcag ggcgaactgc gcgagcatct cgggagtggg
     9541 gtccacggtg gcgccggcgt cgatcagcac ggtggccccg cccgccgtcg tcggcagcgc
     9601 aacggccagc gcggggcgca gaatgtcggg cgcggtgccc agccggtcga ccgcgcaggc
     9661 ggcgacggct cccgtggacc cggccgacac gaaggccgca ccggctccgt cccggacgag
     9721 gccgagcccg accgccaggc tggagcgggc catgcggatc gcccccgcgc cgcgctcggt
     9781 catcgggacg acgtcgtcgg cgtgcgccac gtcgatctcg cccaccgccc cgagccgggc
     9841 cagctccgcg cgcaccactc ccgcccggcc ggcgaggacg accggcacgc cgtgctcccg
     9901 ccgggcctgg accgcccccc gcacgatctc ggcgggcccg tggtctccac ccatggcgtc
     9961 caccacgacc ggcggggagg cggtcggcac gtcccgcatg tcaggccacc cccacccggc
    10021 gctcggcctg cgcggcggcg cgggcggcga gcaggttacg ggtgaagatc gcgagcctgc
    10081 gcccgcgcgg caccgtggcc cgccgcgcca gcacgtcgtg gccggccgcc gtgatctcgt
    10141 ccaggatgcc gccgtacagc tcgtacgccg cccggatgca gggccgcgac gacggcgcga
    10201 gcagcgcgat cccctcccag gcccggcggt agtggtcacg ggcgcgttcg cagttcaggg
    10261 ccaccagatc gcgtacggcc ggggtggcgc gcggcgcggc gaggtcggcc ggggtcacgc
    10321 cgaacttgtc gaggtcggcc agcggcaggt agatccggcc ccgcgccagg tcctcgcgta
    10381 cgtcgcgaac gaagttggtg agctggaacc ccaggccgag ctgccgtgcg ggctcgcggg
    10441 cccgctcgtc ctcccctggc aggggttcca gcacgggcag catcatcgtc ccgatggccg
    10501 ccgccgagcc ctccatgtac cccagcaggt cgtcgtacgt cgcatacctg cgcacggtca
    10561 ggtcggcccg catggacgcc aggaacgccg ccacgtcggc gtggtcgatc ccgaaggccc
    10621 tgaccgtgtg cgcgaaggcg ggcagcaccg ggtcgcggac cggctccccg cccagcgcgg
    10681 cggtcagccg ggaggcgagc cgttccagcg cccgggaccg gtcgccgccc atcgagaacg
    10741 agtcgacgat ctcgtcggcg tagcgggcga agccgtacaa cgcgtggacg tgcggccgtt
    10801 tccaggcggg cagcagcagg gtggcgaggt agtaggagcg gccgtagcgg gcgtgcagcc
    10861 tgcggcaccg ctcgtacgcc gccgtcagcg tggcggacga cggtgcggac gacggtgggg
    10921 gcgacgttct catggagtgc tctccaggat gcgttcggcg gccaggcggc cggagatcag
    10981 cacgggcggc accccgacgc cgggggcggt gtacatgccc gcgaagtgga ggccggggac
    11041 ccgccgcgcc gcgccggacg gccggaacca ggccgtctgg gtgaaacggg cgtcgagggc
    11101 gaacggcgtg cccgcggagt ggccgcgccg ccgccaggcg gggggatcga acacgagccg
    11161 cggcgtcgcg gacaggtcgc cgtacccgag gccggagagc cggtcgagca tgcggttcac
    11221 cagacggggg gtgagggcgg cccagccggc gccgcccgtc aggttcgcgg tgggctccag
    11281 cacgctcagc acggcgggcc ccgcgccgcc gggcccgtgg tcgtctggcc cgtggtattc
    11341 aggacaggtc accagcaggc tcgggtccgg ctgcggggcg cccgcctcca gcgccgcgaa
    11401 cgtcgcccgc cactcccggc cgaagtgcag ggtgtggtgg gcctggccgt ccggccgccg
    11461 gtcgagggcg aagtgcgcga ccaggcacga aggggagaac cggggacggc ggagccgcca
    11521 gtcggccgcc tcctccggca gcaggccgtc gccgccggcg ccgtgggcgc cgacgaggtc
    11581 gcaggccacc accgcgtgcc gggccgcgat ccgctcgccc gtgtcgagcc gtacggccct
    11641 caccccggcg ccgtcggtct cgatgcgggt ggcccgcacc ccgtaccgga agaccgcccc
    11701 ggccttctcc gcggcggcgg ccatggcccg ggggacggcg tgcatgccgc cctcgcgggg
    11761 gaagtacacc ccgccgacgg tgtccatgtg ggcgatcacc gcgtacacgc cgagcgcgcg
    11821 ctgcggcgac cggccgacgt acaacgactg gaacgtgtgc gccctgatca gccgctcgtc
    11881 ggtgaggtgg cgccgcacga ggcggtccag ccggcggaag ccgccgagcg cggtcagccg
    11941 ggccagcgcg tacggccggg ccagcgcgcg cagccgggtc atgtcgctgt cgatgaacgc
    12001 gtcccactcg gccgcgaaca tctcgccgag cagcccccgg aaccggcggt agcgcgcggc
    12061 ctccgcgggc ccgcacagcg cccgcacctg gtcctccatg gcgtccgcgc ccgcgaccac
    12121 gtcgagccgc gacccgtcgt ggaaggtcag ccggtagtac gggtcgagcc ggcgcagcgg
    12181 cagccagcgc tccatgtcct gcccggccgc ggcgaaggtg tcggcgagca cccccggcat
    12241 ggtcagcacc gacgggccgg tgtcgacgcg gtgctcgccg aggacggccg tgccgcagca
    12301 gccgcccggc acgtcggcgg cctccacgac gatcacctca cggccggtcc cggccaggcg
    12361 catcgcggcg gccaggccgc cgaggcccgc gccgacgacc acgaccggcc cgcccgcggc
    12421 catcagacgg tcctgcgggt cgtcgtcgtc atgcgcgctg ctccttcggt cgttccggtg
    12481 atcgcggccg gtccggcgat cggcggccgt ttcggtgatc ggcggtgccg tcagtagagt
    12541 tttcgcgccc tcccgctccg gcggttgcat ccatgcgatc gcatccgtgc gtgcatccgc
    12601 accgggcctc cgggccgaaa caaggcgagg gacgaccggc acggcatggt ggccggaggg
    12661 tgggagcggt ggggcggcag gggcctgagc gacggcgggc ctcgggaaac ggcggccggc
    12721 acaggccgca cgcagtggcc ggaagcacgg atcggaagca gcggacggac acggcggaca
    12781 cggcggacac gggggtgagc gggtgaggcg ggacgggcag ccggggacgg acggcgacgc
    12841 cgtctccgag gaggagccgg gctacggcat cggagccgtc gcccgccggc tcggcgtgcc
    12901 cgcgtccacg ctgcgcacct ggaacctcag gtacggcatc ggcccgagcc ggcgcagccc
    12961 gggcgggcac cgccgttacg acgaggcgga cctgcgccgg ctccaggaga tgaaccggct
    13021 ggtccggtcg gggatgccgc cggccgacgc cgccaatttg gcgctccggc agcgcccagc
    13081 ggcggcgggg gagcggagca ccggcgagcc ggcggccggt gagccgagga ctggtagggc
    13141 gaggaccgcc gagcagggag ccgccgagca ggcggcgttc ccggccggag gggtggccgc
    13201 ggcgccgggc cgtccggcgc cgcgtccggc gcgcggcctg accggcggtc cggcgggttc
    13261 cgccgcgccg cccgaatccg ggctcacgtc cccgtccaca tcggcgcgcg aggtcacgcc
    13321 cagagtcgca cccgaactcc cggccgctga acccggcctg ctgtccgcgg ccatgctggc
    13381 ccgcgtcgtg gcggcgatgg acgccccggc cgtgagcgtg gcgctggacg cggcactggc
    13441 cgcgcacggc gtcctgtgga cgtgggagcg gctcgtgctg cccgtgttcg cggcgatcag
    13501 ccgcaggcag caggagaccg gggccgggat cgacatcgag cacctgttct ccaaccggct
    13561 ccaggccgcc ctggtgcggt tcgccgcgca cgcgcccgcg cccgtccacc cccggccggt
    13621 cctgctggcc gccgccgagg aggagcagca cacgctggcg atccaggcgc tggccgccgc
    13681 gctcggcggg ctcgccgtgg agacccgggt gctcggggcc cgcacgccgt actccgcgct
    13741 cgcggacgcc atgcgccgcg tcggcccggc ggcggtgttc gtctggtcgc agacccccga
    13801 gaccggcgat ccggccccgc tcggcggcct gccggggctc cgccccgcct gccggatcat
    13861 cgccggcggc cccggatggg gcgacggcgt gcctacggaa gtcgttcggg tgactacgtt
    13921 tcgtgacgcc atctcggcgg taatgaccac tctgcggtaa ttcgccctct ttggcgcact
    13981 cttgacctga ggtccggccg gtttggttgt catgacgacg cgcggggggc tatgaatagg
    14041 ttttgaatag gttttcgggg catgggggga ccatggagac gacgctggag ttccgcctcg
    14101 ccgcgggaga cacgggcgcc ctgggggagt gctaccgcga gcactccccg gccgtgcgct
    14161 cctacctacg caagctcgtg ccgccacaag acgtggaaga cgtcctccag gtcgtcttca
    14221 ccgaggtctg gcggttcagg caccgcttcg atccgggccg cagcctcgcg gcctggctgt
    14281 tcggcatcgc gcacaaccgc gccgtcgacc acctgagggc gcgtacgccg acgacggtgc
    14341 cgctggaggc ggtcccggac ccggcgggac acgacggacg gcgggacggc gacgagctcg
    14401 ccgaccgcga ccgggtgctc cgcgcgctgg ccgcgctgcc ccaggtgcag cgccaggcga
    14461 tcgagctggc gtactacggc gatctgactc agcgtgagat cgccgagcac ctgcgggtcc
    14521 cgctcggcac cgtcaaggcc cggacggccc ggggcctgca ccggctgtcc gcactgctgg
    14581 aggcggcgtg agcacgatgg agaacgccac ggagagcacc acggagagca ccatggagag
    14641 catgacggcg gaggtcaggc ccagggtggc ggtgtcgagc tgcctgctcg gcgctcccgt
    14701 gcggttcaac ggcggccaca gccgcgaccg gttcctcgcc ggcgagctgg acgagcacgt
    14761 cgactgggtg ccgatctgcc ccgagatgga gatcggcctc ggcgcgcccc gcgagacgct
    14821 ccgcctggag ggcggcccgg acgggccccg gctgctgacc cggcggacgc gccgcgacct
    14881 gaccgccgag atggccgatc tcgccgccga tcgggcggcg gagatcggtg ccgtcgacgg
    14941 ctacgtgttc aagtcgaaga gcccgagctg cgggctccac ggcgtccccg tgtacggcgg
    15001 gtccgctccg ggcgcccccg ggcgccgagg ccccggcctc ttcgcctccg cggtcaccga
    15061 cgcccacccg tcgctggtcg tcgaggacga gggccggctg cacgacgcgg tgctgcggga
    15121 ggcgttcgtc gagcggatct tcgccgcggc ccggctgcgg gcgctgctgt ccggcgactg
    15181 gcgcccccgc gacctggtcg acttccacgc gcggcacaag atgcagatcc tcgcccactc
    15241 gcccggggcg taccgggtga tcgggcggct cgtcgccgcc gctggcgacc tgcccaggga
    15301 ggcgctggcc cgcgagtacg gctgggcctt ccgcaccgcc ctcctggtgc gggccaccat
    15361 cgggcgtcac gtcaacgtgc tgcaccactt cctcggcagg atcagcgcgg acctcgaccc
    15421 ggtccgccgg gccgacctca ccgaggtcat cgaggcgtac cgggcgcacc gggtcgccct
    15481 cgccgtgccg ctggccctgc tgcgccacca cgcgaagggc gccggagcgg gtcaggtcca
    15541 ggagcagacc tacctgtcgc cctacccgga cgcgctgcgc ctgcgcaacc acgtccccgc
    15601 ctgacgggcc cgccgcatcc gtgagtacac cgggctgaaa gggaagaaag gccccttatg
    15661 ggacgcacat cgaagaagac gctgacctgc accgccctcg ccgtgaccgc cgccgccgtg
    15721 gcaggcggcc tcggcaccga cccccgttcc tcctggtacc accggctgcg caagccgtcc
    15781 tggcagccgc cccggcaggc gtacggcctg gtctggacac cgctgtacgc gacgatcgcc
    15841 tacgcctccg cccgcgcgct gtccctgggg gacgagcgct cccggccggc cctgcgccgg
    15901 gcgctcgcgg cgaacctcgc gctcaacgcg gcctggccgc cgctgttctt caaggcccgc
    15961 agcccgcgca tcgcgctcgc cgaactggtc gcgctcaacg cgtcgaacgt cctgctgacc
    16021 cgccgcttcc tccgtcagga ccgcgcggcg ggccttctgc tgctaccgta cacggggtgg
    16081 acgctcttcg ccaccgcgct caacgcctcc atcgcccgcc ggaacccgcc ggaaaaggcg
    16141 taacgggggg ccgcggcgcg cggactccgc gacgggtcgg ggacgggggc tactgggcgg
    16201 cggggtcgag ctggggggag cgctcggcct cgtccggcgg ctcctgggac tccagggccg
    16261 tgaggatcgt ggtgaggacc tcccggaacc tccgcacctg ggtcgtggtg agggggtcga
    16321 acagcacgcg gcggacctcc tccacgtggc ccggcgcggc ctccacgagt gccgcgaagc
    16381 cttcgtcggt gagttccgcg acggtcgtgc gccggtcttc gggccgcttg acccgccgca
    16441 cccagccctt ctcctccagg cgggagacgg cgtgggagag gcggctgacg gagtagcgga
    16501 gaatggagga caactcgctc atcgtcatgg tccggcccgg cgactcggag agcaccacga
    16561 tgatcatgta gtaggcgtgc gggatgcccg agtcacgctg taactgccgc tctagggcgt
    16621 cctggaggag ctggctcgtc ctgatgtagg cgcgccaggt gcgctgctcc tcatcgtcga
    16681 gccatcgcgt gccggacatg cgccaagact accggtcggt cggcacaatc tttgtgggcc
    16741 aaagaccctg gttcgatcgt tccgtgcagg aaagtctcag gggcatggac gaaatggagc
    16801 gcatcgacgc ctactggcgg gccgcgaact acctgtccgt cgggcagatc tacctgatgg
    16861 acaacccgct gctgaccgaa ccgctgagtg ccgagcacgt caagccgcgg ctgctgggcc
    16921 actggggcac cacccccggg ctcaacttct gcttcgccca cctgaaccgc gtcatccggg
    16981 aacgcgacca ggaaatgatc tatatcgccg gtcccgggca cggcggcccg gccgcggtgg
    17041 cgcacgcctg gctggagggc acctacaccg agcgctaccc ccacatcacc cgggacgcga
    17101 ccggcatgcg ccggctgttc cgccagttct ccttccccgg cggcatcccc agccacgtgg
    17161 cccccgagac ccccggctcc atccacgagg gcggcgagct cggctacgcc ctgtcccacg
    17221 cgtacggcgc ggccttcgac aacccccgcc tggtggtggc gtgcgtcgtc ggggacggcg
    17281 aggccgagac cggcccgctg gccaccgcct ggcactccaa caagttcctg aaccggggcg
    17341 gtgacggggt ggtgctgccg atcctgcacc tcaacggcta caagatcgcc aaccccaccg
    17401 tgctggcccg catccccgaa cccgagctgc tcaagctgtt cgaggggtac ggctaccgcc
    17461 cgcacatcgt ctccggccac gaaccggccg agatgcacga gctgatggcc ggcaccctcg
    17521 acacggtctt cgaccagatg gccgacggcg gcccgctgcc gatgatcatc ctgcgtacgc
    17581 cgaagggctg gaccgggccg cgcgaggtcg acgggctccc ggtcgagggc acctggcgcg
    17641 cccaccaggt gccgctgacc gacgtgcgcg accgccccga ccgcctggag acgctgcggg
    17701 agtggatgct ctcctaccgg cccgaggagc tgttcgacgc ggacggccgg ccggtcgagg
    17761 ccgtcacggc cacggtgccg gacgggccgc tgcggatgag cgccagcccg cacgccaacg
    17821 gcggggagct gctgcgcccg ctcgtgctgc ccgacttccg cgactacgcc gtcgaggtca
    17881 agagcccggc caccgcctcc accgagccga cccgcgtgct gggcggcttc ctgcgggacg
    17941 tgatcgccgc caacccggag aacttccggc tcctcggccc ggacgagacc gcgtccaacc
    18001 ggctgtcggc ggtgttcgag gcgaccggca aggagtggga ggccgccctg ctgccgacgg
    18061 acgagaacct cggcccggcc ggccgcgtga tggaggtgct cagcgagcac cagtgccagg
    18121 gctggctgga gggctacctg ctgaccggcc gccacgggct gttcaactgc tacgaggcgt
    18181 tcatccacat cgtcgacgcg atgttcaacc agcacgccaa gtggctggag tcgtcccgca
    18241 agatcccctg gcgcaggccg gtggcctcgc tcaactacct gctgtcctcg cacgtgtggc
    18301 ggcaggacca caacgggttc agccaccagg accccgggtt cctcgacgtg gtggtcaaca
    18361 agaaggccga ggtggtgcgg gtctacctgc cgccggacgc caacacgctg ctgtcgacgg
    18421 ccgaccactg cctgcgctcc cgcgactacg tcaacgtcgt cgtcgccggc aagcagcccg
    18481 tgctcgacct gatgagcatg gacgaggcgg ccgtccactg cgcacgcggg ctgggcatcc
    18541 tggagtgggc ctccaccgac gagggcgccc accccgacgt cgtgctggcc tgcgccgggg
    18601 acgtgccgac cctggagacc ctcgccgccg ccgcgatgct gcgcgagcac ctgcccgaac
    18661 tgaaggtgcg ggtggtcaac gtggtcgacc tcatgcggct gcagccggcc tccgagcacc
    18721 cgcacgggct gcccgacgtg gagttcgacg cgctgttcac caccgaccgg ccgatcatct
    18781 tcaacttcca cggctacccg tggctgatcc accgcctgac ctaccggcgt acggggcacg
    18841 agaacctgca cgtgcgcgga tacaaggagg agggcaccac caccacgccg ttcgacatgg
    18901 cgatgctcaa cgacatcgac cgctaccacc tggtgatgga cgtgatcgac cgggtgcccg
    18961 gcctgggcag cacggccgcc cacctgcgcc agcgcatggc cgacgcccgg ctgcgcgccc
    19021 gcgcctacac ccgcgagtac ggcgaggacc ccgccgagat ccgcgactgg acctggcccg
    19081 cctcctgacc cggcgcggcc gggagccggc acgacaaaac gagacgccga caccgtcgac
    19141 gggttccccg gcctcagggc cggggttcag ccctcctggc gcaggtcaaa ggagatggcg
    19201 gctctgctcc tgtccggacg ggcatcggca tgcacgcgtg ctccgtacac ctgccacacc
    19261 cggtcacgtt ggggaggaac gagggcatga cacctgaggg gtatggtcgt tcgccggccc
    19321 ggcacccgtc ggcgtccgcg ctgctgatca ccgacgaagc gagccgggct ctgctggtgc
    19381 ggcccacgta caaagacggc tgggagtttc ccggcggggc cgtcgacccc ggtgaaaccc
    19441 cctgggaggc cgccgtccgg gaggccggcg aggaactcgg catcacctgc cgcatgcccc
    19501 ctgtgctgct gtgcgcggac tggatgcgcc ctcgtggcca cgacctcggg gggttccgcc
    19561 tcgtgttcga cggcggcgtg atgaccgcgg gcgaactggc ggagatccgg ctgccggtcg
    19621 aggagctgag cgactggacg ctggccgacc ctgctgacgc ggccgcgtac ctgcctccgg
    19681 agcgggtgcg ccgcctgcga gcagccgtcc aggcgcgggc ggccggccgg atggcctacc
    19741 tggaagacgg ccacccggtc acctgacccg ttgcggtcag gcgccgaggt cgcgcagcac
    19801 ctctcggccg gcgccccggc cgtgcgcggc aggagccggg tgatgtcgtc agctcgtgcg
    19861 gccggcgacg acaccagcga ggtggggtaa ccggcgggca tcttggtcga gtgcctgccc
    19921 gccggctcgt acccgccggt gaagtccccc gaaggggcct gatgcggtga ctctccccgt
    19981 cgaagctgcg gctgcacccc gacgtgcaat ccgcgtcacg aactccgcat gatcacgtgg
    20041 tggctgttct catgccacct caacgcgaag ttccctggag tactggtcgg cgactgggtg
    20101 atcagttgtg aagcttccca ctggcgccgc cgcagctcca gtagatgcgg aggtagtaag
    20161 acccatagag gccccctacg gtgccgctca cggtccccga gccgacgtgg cggtggtaga
    20221 cgaccacccc gttgccggcg tcgatgatct ggaagtcggc ctgagcgcag aggaagccgc
    20281 cttccacgta gtaggcgatc tcgtgggcgc cgctcgcggg aatgttggcg gtggtgcacc
    20341 cggaggaacc gaggttcacg acacagttca cctccgtgta cgcctgcgcg gtacccgtcc
    20401 ccagcgcgct ggcggttgcg aatcctgccg ctgcgagcac tgccccggct acgcgtcttt
    20461 tcagtcgatt catggctagc ctcccgtgat gatctcttct agtaaagatc acctgacaag
    20521 tggtaaaccg tcaatgtctg gagggcgctt ttttggacgg acggacgccg ggattcggcg
    20581 ttggtggccg gcctttgctt tcgatgtcac gtgccggggc gtaccaggcc gctctcgtag
    20641 gcgaggatga ccagctggac ccggtcgcgc acgtccagct tggcgatggc cctggtgatg
    20701 tgggtcttgg cggtgagagg gctgatgacg aggcgctcgg cgatctcgtg gttggagagt
    20761 ccgagcgcca cgagcttgac cgtctccagc tcccgggagg tgaggacggt cagccgctgt
    20821 cccgcgccgg gcgtgaggtc ctgccggtgg gcgaactgct cgatgacacg gcgcgtcacc
    20881 cccggagaca ggagcgcgtc tccgtcggcg acggcggcga ccgcccggcg tag
//
