LOCUS       NZ_VYTZ01000008        21122 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold8, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000008
VERSION     NZ_VYTZ01000008.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 421897)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 421897)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 224419
            Orig. end                         :: 245541
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000008.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21122
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RRE-containing"
                     /region_number="3"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     cand_cluster    1..21122
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21122
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:11122](-)"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11122)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     gene            923..1504
                     /locus_tag="F5972_RS23630"
                     /old_locus_tag="F5972_23630"
     CDS             923..1504
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020543422.1"
                     /locus_tag="F5972_RS23630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23630"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150935933.1"
                     /transl_table=11
                     /translation="MGNREDLLAGARRCLMEKGYSGTTARDIATAAGTSLASIGYHFRS
                     TKALLNAALVEAMEEWGQEIERTLAAGPALGGTPAQRFEATWTRIIESFARLRPLWAIQ
                     FELIAQMDRLPELREAFAAANRQAKLGLAALFENLDPDADARKAMAVGAFYQALLGGMA
                     AQWLVDPDEAPSAADLAEALRTITPGLATQ"
     gene            complement(1538..2182)
                     /locus_tag="F5972_RS23635"
                     /old_locus_tag="F5972_23635"
     CDS             complement(1538..2182)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF044515.2"
                     /locus_tag="F5972_RS23635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23635"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150935935.1"
                     /transl_table=11
                     /translation="MASDTGRSAGDGRTRRADASRNAALLLAAARELIAESDSEVVLDG
                     VALDEVARRAGVGNATLYRHFPTRGDLLVALYADEVAALCRRGAELSETARPIDALFAW
                     LEEFVVHVATKRALAFAATEGPTGRRTEQFDRWHTSIRSSAAELLAGARQAGAVRPDLT
                     VTDLLALASGVALTATDVAHARRLAALLRRGVENDADGPERRHATPHDGSS"
     gene            2279..2680
                     /locus_tag="F5972_RS23640"
                     /old_locus_tag="F5972_23640"
     CDS             2279..2680
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024966.5"
                     /locus_tag="F5972_RS23640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23640"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_150935937.1"
                     /transl_table=11
                     /translation="MTLSAEDRVAVTDLINRHGHLTDHGELDRWSELFTPDVVFDLTGM
                     GGGVLTGLAALRDVTSAMAGEHPVAHHVTNIVLDETADDHVRALSKGIGVMADGTTGSV
                     TYDDTIVRGGEGWRISRRAIRARRAPLTP"
     gene            complement(2710..3357)
                     /locus_tag="F5972_RS23645"
                     /old_locus_tag="F5972_23645"
     CDS             complement(2710..3357)
                     /GO_function="GO:0070273 - phosphatidylinositol-4-phosphate
                     binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019634331.1"
                     /locus_tag="F5972_RS23645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23645"
                     /product="GPP34 family phosphoprotein"
                     /protein_id="WP_225311771.1"
                     /transl_table=11
                     /translation="MDVPGSLPARLYLLGYDARKERVVTNYRSPYLLRAAALTELLLDG
                     RIADERGKVRVVSEEPLGDPVLDDLLRQIAGSRPRSWRHWIDKDGRATVRAVRDELETR
                     RWVRVELRRPFLLVFNRTRVRVRDTRVVKRLAAQVSAALNGPVSRVGEREAALVVLAAA
                     GELRTVLPRARRKAYKQRIAELGERGGPAAPALRKVIQQLHAASAAAMGGAG"
     gene            3573..>3797
                     /locus_tag="F5972_RS38330"
                     /old_locus_tag="F5972_23650"
                     /pseudo=""
     CDS             3573..>3797
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF033573.1"
                     /locus_tag="F5972_RS38330"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23650"
                     /product="transposase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MWCPKYARSVLSGRAGDRREELIYATAGEHGCQIAALDVMPDQGR
                     LFVTPNPNNSPSYVASKVTSFTAHHPRGGF"
     gene            3827..4714
                     /locus_tag="F5972_RS23655"
                     /old_locus_tag="F5972_23655"
     CDS             3827..4714
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1192: transposase"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF040570.1"
                     /locus_tag="F5972_RS23655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23655"
                     /product="RNA-guided endonuclease TnpB family protein"
                     /protein_id="WP_191910285.1"
                     /transl_table=11
                     /translation="MVKVLLRGQGRGDAVEWPKNGDGCRWDSQPEHPSAMFVRLQGVGH
                     VRVHQHRPVRGRVKTIGVKREGDRWYVVLACDDVPAEPRPATGAVVGLDMGVACLVTTS
                     GGVHVANPRHLAATADRLAEAQRDLARGRRGSTRRRKKAERVAALHGKVRRQRIDYAHK
                     AALTLVRAYDVIVHEDLRIANMTRSASGTIEAPGRNAAQKSGLNRSILDAGWGVFLTVL
                     AYKAESAGRELIAVNPAGTSRTCARCGHCAKDNRLTQAEFVCTACGHAAHADVNATTNI
                     LRAGLALRRAAEAA"
     gene            complement(4765..5037)
                     /locus_tag="F5972_RS23660"
                     /old_locus_tag="F5972_23660"
     CDS             complement(4765..5037)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017558131.1"
                     /locus_tag="F5972_RS23660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23660"
                     /product="hypothetical protein"
                     /protein_id="WP_204285839.1"
                     /transl_table=11
                     /translation="MATDRKSILLRLDPAVHDALARWAGDELRSTNAQIEFLLRRALAD
                     AGRLPRDAARIPRRGRPPRTSAPPDGSAASPESEEPGGGAPPGDD"
     gene            complement(5040..5966)
                     /locus_tag="F5972_RS23665"
                     /old_locus_tag="F5972_23665"
     CDS             complement(5040..5966)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657876.1"
                     /locus_tag="F5972_RS23665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23665"
                     /product="SPFH domain-containing protein"
                     /protein_id="WP_150935941.1"
                     /transl_table=11
                     /translation="MTDLQIAVDMPAPQTNERAARETAGWPLLILALVGLLSPFVLVPA
                     GISIAAGGSTGPGVVLAVAGVLLLLAAVVALTGLTAVAPGEARVIQLLGRYVGTVRTPG
                     LRFVVPFTQKRRVSTRIRNHETDVSKVNDADGNPIEMAAVVVWQVEDTAKAVFEVDDFV
                     EFVAFQTETAVRHIAGSYPYDGHDDVLSLRQNADEITGRLSAEIQARVASAGVSVIESR
                     ITRLAYAPEIAQAMLRRQQAGAVVAARQRIVEGAVGMVEAALARLDEHDVIELDEERKA
                     TMVSNLLVVLCGDRDVQPVVNTGSLYR"
     gene            complement(6059..7048)
                     /locus_tag="F5972_RS23670"
                     /old_locus_tag="F5972_23670"
     CDS             complement(6059..7048)
                     /NRPS_PKS="Domain: PKS_ER (17-323). E-value: 4.1e-43.
                     Score: 139.6. Matches aSDomain:
                     nrpspksdomains_F5972_RS23670_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890842.1"
                     /locus_tag="F5972_RS23670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23670"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_150935943.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 2.1e-18, bitscore:
                     61.2, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKAIVQDAYGPADVLEPRDVDRPSIGDEEVLVEVRAAAVDPGVWV
                     LMTGRPYLMRLAGFGVRRPKVPVRGRDVAGVVAAVGARVTRFRPGQEVYGTCESGSYAE
                     FAGARQSRLAPKPTGLTFEQAAAVPVSGMTALQAVRDVARVRPGQRVLVIGAAGGVGSF
                     AVQIAKAYGAGVTGVCSAAKAGLVRSLGADDVVDYAREEIDRDGPRYDVVVDTAGNRPL
                     SLLRRALTPRGTLVIVGGGHTAYRFTGGMGRTFRAPLLSMFVGQRLRPVMSRERSEHLE
                     ELTRLVESGAVTPAIDRVYPLADAPDAIRHLMGGHPGGKVVVTASGTA"
     aSDomain        complement(6080..6997)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS23670_PKS_ER.1"
                     /evalue="4.10E-43"
                     /label="F5972_RS23670_PKS_ER.1"
                     /locus_tag="F5972_RS23670"
                     /protein_end="323"
                     /protein_start="17"
                     /score="139.6"
                     /tool="antismash"
                     /translation="RDVDRPSIGDEEVLVEVRAAAVDPGVWVLMTGRPYLMRLAGFGVR
                     RPKVPVRGRDVAGVVAAVGARVTRFRPGQEVYGTCESGSYAEFAGARQSRLAPKPTGLT
                     FEQAAAVPVSGMTALQAVRDVARVRPGQRVLVIGAAGGVGSFAVQIAKAYGAGVTGVCS
                     AAKAGLVRSLGADDVVDYAREEIDRDGPRYDVVVDTAGNRPLSLLRRALTPRGTLVIVG
                     GGHTAYRFTGGMGRTFRAPLLSMFVGQRLRPVMSRERSEHLEELTRLVESGAVTPAIDR
                     VYPLADAPDAIRHLMGGHPGGKVVV"
     CDS_motif       complement(6545..6607)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS23670_0001"
                     /evalue="1.10E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="F5972_RS23670"
                     /protein_end="168"
                     /protein_start="147"
                     /score="17.9"
                     /tool="antismash"
                     /translation="GQRVLVIGAAGGVGSFAVQIA"
     gene            complement(7045..7278)
                     /locus_tag="F5972_RS23675"
                     /old_locus_tag="F5972_23675"
     CDS             complement(7045..7278)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890616.1"
                     /locus_tag="F5972_RS23675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23675"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_150935945.1"
                     /transl_table=11
                     /translation="MVKPTRVTNRIRTLRFTHDEMTQAELAERIGVTRQTLIAIEQGRY
                     SPSLEMAFRIARVFGVPLDDVFQYPESPEETP"
     gene            complement(7272..7700)
                     /locus_tag="F5972_RS23680"
                     /old_locus_tag="F5972_23680"
     CDS             complement(7272..7700)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012890617.1"
                     /locus_tag="F5972_RS23680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23680"
                     /product="hypothetical protein"
                     /protein_id="WP_150935947.1"
                     /transl_table=11
                     /translation="MTHLEKRAWIRLVVSVLAYAAYVVVVLRRADGGPLPDVPYTAALL
                     WTIGGAIAATIAAEIGMAIVNPRASRVQDARDREIGRFGDHVGQAFVVIGAVAAMLMAM
                     AGWDRFWIANVVYLCFVLSAVLAGIAKVVAYRRSLPEW"
     misc_feature    complement(7596..7598)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    7769..7778
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    7771..7784
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.27"
                     /tool="antismash"
     misc_feature    7771..7785
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.59"
                     /tool="antismash"
     gene            complement(7794..9008)
                     /locus_tag="F5972_RS23685"
                     /old_locus_tag="F5972_23685"
     CDS             complement(7794..9008)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS23685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_23685"
                     /product="hypothetical protein"
                     /protein_id="WP_150935949.1"
                     /transl_table=11
                     /translation="MSQDAGRAADGTRVRLRDLAFRRDGSQWIVGRPDGQEFAAVPYEG
                     MRAIRLLMEGATVEETERRLRGETGADLDVRDFVRALGELGFLEEPGGPATPPEPPTFP
                     RLRARHVRWTLHPLVHTAVAGLVAAGAVTAVIRRETLPGWHDLLWSEHGTLVLLSEIAV
                     GWTLIFLHEMAHLSTARAAGVPGRIRLGTRLQFLAVQTEVSGIWLAGRRVRLTVYLAGM
                     AVDAAACSAAVILAAVLGRHTVLSLVTLTSASMLTTQFLVFMRTDVYFLLQDLTGCRNM
                     YGDATAYARHLALRLLGRPSPDPLAGLPRRERRSLRAYAVLMVVGTAVCLGAAFAVTLP
                     ATLVLLCRAVRALVTPAGLLSVLDAATVLLAALAFQVAWARAWWRRHGARLRGTLSRLL
                     TRPRP"
     gene            complement(9036..9677)
                     /locus_tag="F5972_RS23690"
                     /old_locus_tag="F5972_23690"
     CDS             complement(9036..9677)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045158.2"
                     /locus_tag="F5972_RS23690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23690"
                     /product="DUF6879 family protein"
                     /protein_id="WP_150935951.1"
                     /transl_table=11
                     /translation="MESTRTVFDDVRQAEARVLPADAYQAEFAEEFDQAPGVVWKLERA
                     QEFHEPDVPSWRAMMAGDWERSLALIAEMREPLTGYYRTHPETRRLRVVETPLTPYLQW
                     ELHVLAVRAAAGERPRVLPAGAVREFERTAPLPEIVVVGPSLLYEVLYDEIGEHVGARR
                     ITDPGLAGPCRAVIGTLYERGEDVRSYVEREVLPLPPPAVSSRPRGTFRP"
     gene            complement(9779..9904)
                     /locus_tag="F5972_RS38930"
     CDS             complement(9779..9904)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS38930"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_263641856.1"
                     /transl_table=11
                     /translation="MNPNESELETADEAAAPVKTKITIRLLDKIETTNASNSVGN"
     misc_feature    9975..9989
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 16.28"
                     /tool="antismash"
     gene            complement(10001..11122)
                     /locus_tag="F5972_RS23695"
                     /old_locus_tag="F5972_23695"
     CDS             complement(10001..11122)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Pantocin_Microcin_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ThiF"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013094.5"
                     /locus_tag="F5972_RS23695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23695"
                     /product="ThiF family adenylyltransferase"
                     /protein_id="WP_225311773.1"
                     /sec_met_domain="Pantocin_Microcin_RRE (E-value: 1.6e-18,
                     bitscore: 61.3, seeds: 9, tool: rule-based-clusters)"
                     /sec_met_domain="ThiF (E-value: 6.2e-48, bitscore: 157.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRLPRVKFEHRPHRYEDGTIRIGGEIHGIAAEIEDPRGWVWTALC
                     LMDGTRSREDIADRLRSAHPELPDAESVVEQLVETRYVEDAAAVPPAALSERELDRYSR
                     NQAFFRVVGPGPHSWEVQLRLKSARVVVLGLGGTGSHAAWALAAAGVGEIHCVDPDLVE
                     LSNLNRQVLYGEADVGRPKSEAAVARLRGVNSDITVTGDRRRIGSRRELDTLIAGYDAL
                     ALCADRPDGHGIRVWANRACAAARIPWVGGGYSGPLVTVGCFTPGAGTCYECLCDGEEA
                     RRRPGTPVDLGGPGVIATSAGLSGQFVAHALIGLLTGVSAPPVGVIRGVNLIAGDHHVW
                     VSHPPRPGCPVCGTRARARFDSTERISPARPKQ"
     aSDomain        complement(10841..11122)
                     /aSDomain="Pantocin_Microcin_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing E1-like protein in a
                     pantocin/microcin cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F5972_RS23695_Pantocin_Microcin_RRE.1
                     "
                     /evalue="1.10E-19"
                     /identifier="RREFam017.1"
                     /label="F5972_RS23695"
                     /locus_tag="F5972_RS23695"
                     /protein_end="94"
                     /protein_start="0"
                     /score="61.3"
                     /tool="antismash"
                     /translation="MRLPRVKFEHRPHRYEDGTIRIGGEIHGIAAEIEDPRGWVWTALC
                     LMDGTRSREDIADRLRSAHPELPDAESVVEQLVETRYVEDAAAVPPAAL"
     gene            11318..12334
                     /locus_tag="F5972_RS23700"
                     /old_locus_tag="F5972_23700"
     CDS             11318..12334
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013618.5"
                     /locus_tag="F5972_RS23700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23700"
                     /product="lytic transglycosylase domain-containing protein"
                     /protein_id="WP_150935955.1"
                     /transl_table=11
                     /translation="MNDQRARTSRVPFLPASRRPRVLAGLLAAGLAGLVSLSGCAGARG
                     EGSPAVSGGAEAPAASATPPERPSGDPSAPVKPDQSPSAEPPAPDAKIPKDPAALAAAL
                     TRTTALLRDAVDDWRREGDPAKGQAPEPVVLLSLYEQRLFRHLARNPGVASRTYGRLPK
                     DQAARARDNVTAIRDLLSLAHPVSGPVKFRIEPPEPADVLLEGFRRAGRRFGIDWQVLA
                     AVMLVETKFGRVRSPSYVGAKGPMQFMPGTWKAYGMGGDIEDTTDALLAAANYLHASGA
                     PGDYRRALYAYNHSQAYVDAVLLHARQMKRDIRNYYAYYTWQVYVITTKGERRLSGP"
     gene            12457..14967
                     /locus_tag="F5972_RS23705"
                     /old_locus_tag="F5972_23705"
     CDS             12457..14967
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040347.4"
                     /locus_tag="F5972_RS23705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23705"
                     /product="DUF6185 family protein"
                     /protein_id="WP_150935957.1"
                     /transl_table=11
                     /translation="MGTTRVAVALGAAALTSVLLAATALGPRPALAAAAPCASGAPASA
                     WIETSVTVEERGHDTAVLRSTTWVGVPRDWAGAAALLGATTTDGCLLPEGGSSSATMSP
                     DGAEVVVRHTEETPVQLYGAEWIGEPAGLWSSRTSGRTCYVALLPAPADLPPGLAKARW
                     RAVAVRAPDSGVRGVQPLPSEVRPDHTYVWRDAAAPPRVEVALRMSARSEFQRWAGSRG
                     ADVLTVVTYLGFALPYLLPAVLLVLLRRRSADPGERALAGIMLGALALITAVETITAVL
                     VLSGTAFAAHLLGLTDVGAIVILAAPLCAAAWRSARRRIRRPGPVSTGPVSPDAGPTGS
                     GLDTLSAPAFGGVVLAGVALVAVSGFGPLAVRHADEQPDLILPASAVATALLLTGAAWV
                     IAVRAARVPDRRTPRAVRTLLQWSVPGLALLTLGFVAHAAATGLLGFWGNLPRVVGSPF
                     FLLENLAYLMWPLVVLLLLLLLRLYGRRTDTVGPLTAWLVVFLFVVGTIRWPSTYAGMP
                     VPLAALTGLTVLPLLLRLTRRAEPPDPGVSRRRLAVIVEEHRTLEAREKGLRRRWAAGD
                     MDDAAYHRENEPVVDRIGRLRGEIGLDPRREDGLTPLDLALSRGPGGSWWANARLASRY
                     ASYVGAPAAVFLIWATWSADSTGHDGWLDRLREPNGFYGLAGDLIGGLLIWPVAGFVLG
                     ALWRRLPGRRGYLKGVVPVLAYGAATGAHAMLNNLIGQAPVRGSLVRVLLLFLVLTVVA
                     VLMDARTLQTRPGGLASRLTPVAVVYRLGTAGSGIALIVAQAAAILGLWTQLRHGIDIT
                     SQVDTSTQAPPSTDAQLFQSRPGG"
     misc_feature    14242..14244
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15004..16842)
                     /locus_tag="F5972_RS23710"
                     /old_locus_tag="F5972_23710"
     CDS             complement(15004..16842)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0030245 - cellulose catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF013504.5"
                     /locus_tag="F5972_RS23710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23710"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_191910286.1"
                     /transl_table=11
                     /translation="MAFGDNRFLRGLLTAVTATALGGAGLVLGTTSADAAVGCEVTYAT
                     TQWGTNSGGFTAGVTVTSTGESLNGWRLTFSFPGSQRLTQGWSARWTQLAEHVVAENEA
                     WNGTLPSGGSVHLGFNGAWTGSNPPPTDFAVNGVPCQVTLVPSPSPSASASPSAGPSRS
                     PSPSPSPSPSPSPSPSPSVSPSPDVPVDNPFTGATGYVDPDWAADVESSAAKVDDATAA
                     KMRGLKTTSTAVWLDRIADVTGGPGVTRTLKDHLDEAVRQNAGYVTLVLHDLPDRDCRS
                     LVSSAELHEAQGGLNRYRTEYVDAIAAVLARPEYRNLRVATVVEPKALIDLIVGVSAGI
                     FPCQQAQQSGVYLTGIQYALNRLSPLPNVYTYLDAANASLAGWDTNFTQLTTLITETVR
                     GTAAGMHSLDGIATNVADYVPLTEPFLPDPTHTVAGQQLIMSRFYDWNPHFDERDYALA
                     IRAALVAKGLPSSLGVVIDTSRDGWGGPGRPTAVSTSLDLNTYVDQSRVDRRPSRLATC
                     NQNGAGLGARPVAAPVPGVDAYLWIKRPGESDGAGGPILPEGSDRLVDRVCDPKGNLTP
                     WSDTIRPTNALPNAPLYGDWHHEQFVMLVNNAYPAL"
     misc_feature    16966..16979
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 19.31"
                     /tool="antismash"
     gene            complement(17093..17929)
                     /locus_tag="F5972_RS23715"
                     /old_locus_tag="F5972_23715"
     CDS             complement(17093..17929)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019610908.1"
                     /locus_tag="F5972_RS23715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23715"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_150936281.1"
                     /transl_table=11
                     /translation="MISIGTADRRTTVTDGPGSPAIDSSASHSARVWNYLLGGKDHYAV
                     DREDGDMILRMFPDIARIARQQRGFLVRAVRYLTAEAGVRQFLDIGTGLPTADNTHQVA
                     QRVAPDSRIVYVDNDPLVLVHARVLLTSTPEGRTAYIEADVRDTDTILATARNTLDFDR
                     PVALMMLGILGQLRDEENPGAVAARLLDALPSGSYLAVSDGTDTSEALVRAIEVYNANS
                     ASSYHLRTPEAIAGFFDGLELVDPGVVTTSRWRPDVADVESGPRAVASFCGVGRKP"
     gene            18027..19001
                     /locus_tag="F5972_RS23720"
                     /old_locus_tag="F5972_23720"
     CDS             18027..19001
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019144.5"
                     /locus_tag="F5972_RS23720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23720"
                     /product="Sua5/YciO/YrdC/YwlC family protein"
                     /protein_id="WP_150935962.1"
                     /transl_table=11
                     /translation="MGILTSPGGRAAGASARAGSVPVNLDVHGLRKEHRICPDCVRELF
                     DPRGRRHLYPLVRCRECGPPAGEPRVRPRALCEDCRRECDRPGSRRGPGDAAGCAACGP
                     ALRWDGLLGQDALAKAVEVIGAGGVVALRDGFADQIVCDAGAEPALARMDGAPGPVRVL
                     VRHVSAARELANLSFLDIRALAGRSHPATLVRLREPRLPRAVRRATPDVDLFLPRTPLQ
                     HLLTSRFEGPLAVWDRCDEQALPYDGTLTVGLDLDLDHGFGHGFDRGLDHALDVPARSV
                     SPAPRTSSPAWPVWTSPRQDGRPDPSSAPASAPVSTPVSPLAQ"
     gene            19195..19605
                     /locus_tag="F5972_RS23725"
                     /old_locus_tag="F5972_23725"
     CDS             19195..19605
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS23725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_23725"
                     /product="hypothetical protein"
                     /protein_id="WP_150935964.1"
                     /transl_table=11
                     /translation="MPALAAGRLTLAALAAALASAAVSVAASVATAGEASASTPPLRRG
                     VAAYAAGHGNGHGGGGGQVAAGGVATARQFGSGNGKFNQNLNGVYSPTFMMGQQQTGIT
                     VGGRINTQGAFCGPGPRHCKIWQNMPVNAIGW"
     gene            complement(19886..20230)
                     /locus_tag="F5972_RS23730"
                     /old_locus_tag="F5972_23730"
     CDS             complement(19886..20230)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS23730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_23730"
                     /product="hypothetical protein"
                     /protein_id="WP_150935965.1"
                     /transl_table=11
                     /translation="MRDIPRDIPRGILRAIPRVRVRAARRARALGREIAFGAGRPAGGS
                     SPEGTASTWAMSHARLPRHNAFWMPIPSFATLTETCWVPRLLMGLDAESAGCASSLPAD
                     APRSGCGPGE"
     gene            complement(20342..20695)
                     /locus_tag="F5972_RS23735"
                     /old_locus_tag="F5972_23735"
     CDS             complement(20342..20695)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012894280.1"
                     /locus_tag="F5972_RS23735"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_23735"
                     /product="hypothetical protein"
                     /protein_id="WP_150935967.1"
                     /transl_table=11
                     /translation="MRFVHAVTTGALVLAGLTGTSAAALAGTGPTDPSDSAFAGYQIVT
                     LPNANVPNFTRRTVYCPAGKRAVGGGGEAQGNDAVLVGSFPTADGTGWIALGRQTRYDS
                     VGISVYAICAYTS"
     misc_feature    complement(20738..20752)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.89"
                     /tool="antismash"
     misc_feature    complement(20739..20754)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 17.0"
                     /tool="antismash"
     misc_feature    complement(20823..20839)
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.21"
                     /tool="antismash"
     misc_feature    20964..20979
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.85"
                     /tool="antismash"
ORIGIN
        1 cccgtcgacc agtggtccat gcgcacctgg ctgatcgagt cgaagtagaa gtcgggcgcg
       61 tcccacatgg cgccgaggag acgcgggacg tcccagccct ggcccgcgaa gacctcggcg
      121 agcagcttct tctgccgggt gacgtcccgc ccgtcgccgg cccccggcgg tgacgagaac
      181 aggaacatcg ccctggcgtc ggcgtcccgc cgggttccgt acatcccggc gctccggccc
      241 ggcgcggggt gcatcatctc ggtgcggtcc aggccgaggt ggttgggcac cgtgaagatc
      301 gagatgtggt ggccgaggtc gcggacgaac cgggactcct cgccgaaagc cagcccgcgg
      361 acgttggagt gcaggccgtc ggcacccgct accaggtcga acgtcctcgg agggccgctc
      421 tcgaaggtga cgcgcacccc ctcgggcgtc tggtcgaggg cggcgatgga gtcgccgaag
      481 acgtactcga cgccgtcttc ggccgcggcg cgcaggatcc ggacgaggtc gccgcgcatg
      541 atctcgacgt cgtcgccctc gcggccgccg aacgcctcgg cgctcatcgt cgcgacctgc
      601 ctcccccggg cgtcgacgaa gcgcgcgacg cgcatgtccg tgctgtgccg gcgcacctcg
      661 tccagcagcc ccatgcggcc gacgacgtcg agtgcggcgc cccgaatgtc gatcttgtag
      721 ccgccctccc gcacctcggg agcgcgctcg acgacggtgg gggtgaagcc gtactgccgc
      781 agccagtggg cgagcgtcag accggcgacg cttccgccgg agatcaggat gttcgtcaca
      841 cctcggactg tacaaacgtc tcaaatgttt gtctagtaca gatgtctcag acatcggtat
      901 gtggatcggt taagatctgc gtatgggaaa ccgggaagac ctgctcgccg gtgcgaggcg
      961 gtgcctgatg gagaaggggt actccggcac cacagcgcgg gacatcgcga ccgcggccgg
     1021 caccagcctc gcctccatcg gctaccactt caggtcgacg aaggcgctgc tcaacgcggc
     1081 cctcgtcgag gcgatggagg agtggggcca ggagatcgag cggaccctgg ccgccgggcc
     1141 ggcgctcggc gggacgcccg cgcagcggtt cgaggccacc tggacccgga tcatcgagtc
     1201 cttcgccagg ctcaggcccc tgtgggccat ccagttcgag ctcatcgcgc agatggatcg
     1261 cctgcccgag ctgcgggagg ccttcgcggc ggccaaccgc caggcgaagc tgggactcgc
     1321 ggcgctcttc gagaacctcg accccgacgc ggacgcgcgg aaggcgatgg ccgtcggcgc
     1381 gttctaccag gcgctgctcg gcggcatggc ggcgcagtgg ctcgtcgatc ccgacgaggc
     1441 gccgtcggcc gccgacctcg ccgaggcgct gcgcacgatc acccccggcc tcgccaccca
     1501 gtgacgccgc cggcaggcgc cggatccgga gtgcgcgtca ggaggagccg tcgtgcgggg
     1561 tcgcgtggcg tcgttccggt ccgtccgcgt cgttctcgac accgcggcgg aggagagccg
     1621 ccagccggcg ggcgtgagcg acgtccgtcg ctgtgagggc gacgccgctg gcgagcgcca
     1681 gcagatcggt caccgtgaga tccggccgta cggccccggc ctgccgcgct cctgcgagga
     1741 gctcggccgc ggaggagcgg atcgacgtgt gccaccggtc gaactgctcg gtacggcggc
     1801 cggtcgggcc ttcggtggcc gcgaaggcga gcgcccgttt cgtcgcgaca tggacgacga
     1861 actcctccag ccaggcgaac agcgcgtcga tcggccgcgc ggtctcggac agctcggccc
     1921 ctcgccggca cagcgccgcc acctcgtcgg cgtagagggc gacgagcaga tcgccccttg
     1981 tggggaagtg ccgatacagg gtcgcgttcc cgacgccggc acgccgtgcc acctcgtcca
     2041 gagccactcc gtccaacacg acctcggagt cggactcggc gatgagctcg cgcgcggcgg
     2101 cgagcaggag tgccgcgttg cgcgaagcgt ccgccctgcg tgtacggccg tcgccggcgg
     2161 atcgcccggt gtccgatgcc attcgccgcc tcagcttctt gctacccggg gaaatccacg
     2221 cttagggtaa cagtgctaaa cggggaactc cccgtttgaa tccgcagggg aggacacagt
     2281 gactctgtcc gccgaggacc gcgtcgccgt aacagacctg atcaatcggc atgggcacct
     2341 gacagaccac ggtgagctcg acagatggag cgagttgttc actcccgacg tcgtcttcga
     2401 cctgaccggc atgggcggcg gggtgctgac cgggctggcc gcgctgcggg acgtcacgtc
     2461 cgcgatggcc ggggagcatc cggtcgctca ccacgtgacc aacatcgttc tcgacgagac
     2521 ggccgacgac cacgtgcggg cgctctcgaa gggcatcggc gtcatggccg acggcaccac
     2581 gggcagtgtg acgtacgacg acacgatcgt gcgcgggggc gagggctggc ggatcagccg
     2641 ccgcgccatc cgggcgagaa gggcgcccct gacgccctga cgccctgacg gcaccgggat
     2701 ccgggcgggt cagccggccc cgcccatggc ggcggcggac gccgcgtgca gttgctggat
     2761 gaccttacgc agggcgggcg ccgccggtcc gccgcgttcg cccagttcgg cgatgcgctg
     2821 cttgtacgcc ttccgcctgg ctcgcggaag caccgtccgg agctctcccg cggcggccag
     2881 cacgaccagg gcggcctccc gttcgccgac ccgggacacg ggaccgttga gcgcggcgga
     2941 gacctgcgcc gcgagccgct tcacgacacg ggtgtcgcgc acgcgcaccc gggtcctgtt
     3001 gaagaccagg aggaacggcc ggcgcagctc cacgcggacc cagcgccgcg tctccagctc
     3061 gtcccggacc gcccggaccg tcgcgcggcc gtccttgtcg atccagtgcc gccacgacct
     3121 ggggcgggac ccggcgatct ggcgcagcag gtcgtccagg accggatcgc cgagcggctc
     3181 ctcgctcacc acccgcacct tgccgcgctc gtcggcgatc cggccgtcga ggagcagctc
     3241 ggtgagcgcg gcggcgcgga gcaggtacgg ggagcggtag ttcgtcacca cccgctcctt
     3301 gcgggcgtcg tagccgagca ggtagagccg ggccggcagg gagccgggaa cgtccatcag
     3361 attctcctga gggggtcgtc gccttcaggc gatgggggaa tcgggagcgg gagggccggc
     3421 aaggcccggg ggtgcggtga cctgcctggt ctgcgtatca gagatcgttc cccgttcgtc
     3481 gggtgttgga tttgcggcgc tgtcatgctg atcgtgtgac tcggcaaggg cacgcgtccc
     3541 ccggtgcggc gtatgacctc gggtaccacg tcgtgtggtg cccgaagtac gcacgctcgg
     3601 tcctcagcgg gcgagccggg gaccgccgtg aggaactgat ctacgccaca gccggcgagc
     3661 acggctgcca gatcgcggcg cttgacgtga tgccggacca ggggcgtctg ttcgtcacgc
     3721 ccaacccgaa caactcgccg tcgtacgtgg ccagcaaggt cacaagcttc actgcccacc
     3781 acccgcgcgg cgggttcccg cgcccgcgtt ccccgtcgcc cataccgtgg tcaaggtcct
     3841 gcttcgtggc cagggtcgtg gcgatgcggt ggagtggccc aaaaacggcg acggctgccg
     3901 ctgggactcc cagcccgagc acccctcggc tatgttcgtg cggcttcagg gcgtcggaca
     3961 tgtccgggtg caccagcacc gtccggtccg gggccgggtc aagacgatcg gcgtcaagcg
     4021 ggagggcgac cgctggtatg tggtcctggc gtgtgacgac gtgcccgccg agccgcgtcc
     4081 cgccacgggc gcggtggtcg gcctcgacat gggcgttgcc tgtctggtca ccacgagcgg
     4141 cggtgtgcac gtcgccaacc cgcgccacct cgccgcgacc gccgatcgtc tcgcggaagc
     4201 tcagcgagac ctcgcccgcg gcagacgcgg gtccacacgc cgccgcaaga aggcggaacg
     4261 agtcgccgcc ctgcacggca aggtccgccg tcagcggatc gactacgcgc acaaggccgc
     4321 cctgacgctg gtccgggcgt atgacgtgat cgtgcacgag gacctgcgga tagcgaacat
     4381 gacccgctcg gcgtccggca cgatcgaggc cccgggccgg aacgccgcgc agaagtccgg
     4441 cttgaatcgc agcattctgg acgcgggctg gggggtgttc ctgacggtcc tcgcgtacaa
     4501 ggctgaaagc gccggtcgag agctgatcgc ggtgaacccc gccggcacct cccgcacctg
     4561 cgcccgttgc gggcactgcg cgaaggacaa ccgcctcacc caggccgagt tcgtctgtac
     4621 ggcctgcgga catgcggcgc acgccgacgt gaacgcgacg accaacatct tgagggcagg
     4681 gcttgccctt cgccgggctg cggaagcggc ttagcgagaa gccgctccct tcacggagcg
     4741 gaggagtcac gcggtcgcct tctctcagtc gtctccgggc ggagctccgc ctccgggctc
     4801 ctcggactca ggggaagccg cggagccgtc gggcggagca gaggttctgg ggggccggcc
     4861 gcgccggggg atgcgggcgg cgtcgcgggg gagccgcccc gcgtccgcga gcgcccggcg
     4921 gagcaggaac tcgatctgtg cgttggtgct gcgtagctcg tcaccggccc accgggccag
     4981 cgcgtcgtgc acggcggggt ccagccgcag caggatgctc ttccggtcgg tcgccacggt
     5041 cagcggtaga gggagccggt gttgaccacg ggttgcacgt cccggtcgcc gcacaggacg
     5101 acgagcaggt tgctgaccat ggtggccttg cgctcctcgt ccagctcgat cacgtcgtgc
     5161 tcgtcgaggc gggccagggc ggcctcgacc atgccgaccg cgccctccac gatccgctga
     5221 cgcgccgcga cgaccgctcc ggcctgctgg cggcgcagca tggcctgcgc gatctccggg
     5281 gcgtacgcca ggcgggtgat gcgcgactcg atcacgctga cccccgccga cgccacccgg
     5341 gcctggatct cggccgacag gcggccggtg atctcgtcgg cgttctggcg cagggagagc
     5401 acgtcgtcgt gcccgtcgta cgggtagctg cccgcgatgt ggcggaccgc ggtctcggtc
     5461 tggaaggcga cgaactccac gaagtcgtcc acctcgaaca cggccttcgc ggtgtcctcg
     5521 acctgccaga ccaccaccgc ggccatctcg atcgggttgc cgtcggcgtc gttcaccttg
     5581 ctgacgtcgg tctcgtggtt gcggatccgg gtcgacaccc ggcgcttctg cgtgaagggg
     5641 accacgaagc ggagcccggg cgtacggacc gtgcccacgt agcggccgag aagctggatc
     5701 actcgcgcct cgccgggggc gaccgcggtg agcccggtga gggcgacgac ggccgccagg
     5761 aggagcagca cgccggcgac ggccagcacg actcccggcc cggtgctgcc gccggccgcg
     5821 atgctgattc cggccgggac caggacgaag gggctcagca ggcccaccag ggccaggatc
     5881 agcagcggcc aacccgcggt ctcccgggcc gcccgctcgt tcgtctgggg ggccggcatg
     5941 tcgacggcga tctgcaggtc tgtcatgtgc acgctcctcg atgtctagca cgacactagc
     6001 aaagtgatat cacttttgcc caggggcgcc catcgccgct ttcgcgtacc tcttcagctc
     6061 acgccgttcc gctcgcggtg acgacgacct tgccgccggg gtgtccaccc atgaggtggc
     6121 ggatcgcgtc gggcgcgtcg gcgaggggat agacacggtc gatcgccggg gtgaccgcgc
     6181 cggactcgac gagccgggtc agttcctcca ggtgctcgga ccgctcccgg ctcatcaccg
     6241 gacgcagccg ctgaccgacg aacatcgaca gcagcggcgc ccggaacgtg cgccccatgc
     6301 caccggtgaa gcggtacgcc gtgtgcccgc cgccgacgat caccagcgtg ccgcgcgggg
     6361 tcagggcgcg gcgcagcagg gacagcggcc ggttgcccgc ggtgtcgacg acgacgtcgt
     6421 aacgcggccc gtcccggtcg atctcctctc gggcgtagtc gacgacgtcg tccgcgccga
     6481 gcgaccgcac gagtccggcc ttcgccgccg agcacacgcc ggtgacgccg gcgccgtacg
     6541 ccttggcgat ctgcacggcg aacgacccca cgccccccgc cgcgccgatg accagcaccc
     6601 gctgccccgg ccggacgcgg gcgacgtcgc ggacggcctg cagcgccgtc atgccggaga
     6661 ccggcaccgc ggcggcctgc tcgaacgtga ggccggtcgg cttcggcgcg agcctgctct
     6721 gccgcgcccc cgcgaactcg gcgtacgagc cgctctcgca ggtgccgtac acctcctggc
     6781 ccggccggaa ccgggtcacg cgggcgccga cggccgccac caccccggcc acgtcacggc
     6841 cccggaccgg gaccttcggc cggcgcaccc cgaagcccgc gaggcgcatg aggtacggcc
     6901 ggccggtcat gaggacccac acgccggggt ccaccgcggc ggcgcggacc tcgacgagca
     6961 cctcctcgtc cccgatggac ggccggtcga cgtcacgcgg ttcgagcacg tcggccgggc
     7021 cgtacgcgtc ctggacgatg gctttcatgg cgtctcctcc ggggattcgg ggtactggaa
     7081 cacgtcgtcg agcggaacgc cgaacacgcg ggcgatccgg aaggccatct ccagggacgg
     7141 cgagtatcgg ccctgttcga tggcgatgag ggtctgccgg gtcacgccga tgcgctcggc
     7201 gagctcggcc tgggtcatct cgtcgtgggt gaaccgcagc gtgcggatgc ggttggtcac
     7261 gcgggtcggc ttcaccattc cggaaggctc ctgcgatagg cgacgacctt ggcgatcccg
     7321 gcgaggaccg ccgacagcac gaagcagagg tagaccacgt tggcgatcca gaaccggtcc
     7381 cacccggcca tcgccatgag catcgcggcc accgcgccga tgacgacgaa cgcctggccg
     7441 acgtggtcgc cgaaccgccc gatctcccgg tcgcgcgcgt cctgcacgcg ggaggcgcgg
     7501 gggttcacga tcgccattcc gatctcggcc gcgatcgtgg cggcgatggc cccgccgatt
     7561 gtccacagca aggccgcggt gtacggcacg tccggtaacg ggcctccgtc cgcccgtctg
     7621 aggacgacga cgacgtatgc cgcgtaggcg agcacggaga cgaccagcct gatccaggcg
     7681 cgcttctcca ggtgggtcat gagcggctcc tctcgatgta caacatcttt gacatttcca
     7741 aggtagccaa tctttgacct catgtacaga attttttaca cgacttcgga tggctacggc
     7801 cgcgggcggg tgaggaggcg ggaaagcgtg ccgcgcaggc gggcgccgtg cctgcgccac
     7861 cacgcccgtg cccaggccac ctggaacgcg agcgcggcca gcagcaccgt cgcggcgtcg
     7921 aggacggaga ggagcccggc gggggtgacg agcgcgcgca cggcccggca gagcaggacg
     7981 agcgtcgcgg gcagtgtgac cgcgaacgcc gccccgaggc agaccgcggt gcccacgacc
     8041 atcagcacgg cgtacgcccg gaggctgcgg cgctcccgcc ggggcaggcc ggcgagcggg
     8101 tcgggcgagg gacggcccag tagtcggagc gccagatgcc gcgcgtacgc ggtggcgtcg
     8161 ccgtacatgt tccggcagcc ggtcaggtcc tgcagcagga agtagacgtc ggtgcgcatg
     8221 aacaccagga actgggtggt cagcatcgac gccgaggtca gcgtgacgag ggacagcacg
     8281 gtgtgccggc ccaggacggc ggccaggatg accgcggccg agcaggccgc ggcgtccacg
     8341 gccatcccgg cgaggtagac cgtcaggcgg acgcgccggc cggccagcca gatcccggac
     8401 acctctgtct ggacggccag gaactgcaac cgggtgccca ggcggatccg gcccggcacc
     8461 ccggccgccc tggcggtcga cagatgcgcc atctcgtgca ggaagatcag cgtccagccg
     8521 acggcgatct ccgagagcag gacgagcgtg ccgtgctcgg accacagcag gtcgtgccag
     8581 cccggcagcg tctcgcgcct gatcaccgct gtcacggctc cggcggcgac caggccggcg
     8641 accgccgtgt ggaccagcgg gtgcagcgtc caccgcacgt gccgggcgcg cagccggggg
     8701 aacgtcggcg gctcgggcgg ggtggccggc ccgcccggct cctccaggaa accgagttcg
     8761 ccgagggcgc ggacgaagtc gcggacgtcg aggtcggcgc ccgtctcgcc gcgcagccgc
     8821 cgttcggtct cctcgacggt cgcgccctcc atcagcagcc tgatggcccg catcccctcg
     8881 tacggcacgg cggcgaactc ctgcccgtcc gggcggccga cgatccactg ggacccgtcc
     8941 cgccggaacg cgaggtcacg cagccggacc cgggtcccgt ccgccgcccg cccggcgtcc
     9001 tggctcatcg cggcctccag gcgtgcgacc gggggtcagg ggcggaaggt gccgcgcggc
     9061 cgggaggaga cggcgggagg cggcagcggg aggacctccc gctcgacgta cgaccgcacg
     9121 tcctcccccc gctcgtagag cgttccgatc acggcgcgac aggggccggc gaggcccggg
     9181 tcggtgatcc gccgggcgcc gacgtgctcg ccgatctcgt cgtacagcac ctcgtagagc
     9241 agcgacgggc cgaccacgac gatctcgggg agcggcgcgg tgcgctcgaa ctcccgtacg
     9301 gcgccggcgg ggagcacccg cggacgctcc ccggccgccg cccggacggc caggacgtgc
     9361 agttcccact ggagataggg ggtgagcggg gtctccacga cgcggagcct gcgggtctcc
     9421 gggtgggtcc ggtagtagcc ggtgagaggc tcccgcatct ccgcgatcag ggcgagggaa
     9481 cgttcccagt cgccggccat catcgcccgc cagctgggga cgtcgggctc gtggaactcc
     9541 tgggcgcgtt cgagcttcca caccacaccg ggggcctggt cgaactcctc ggcgaactcg
     9601 gcctggtagg cgtcggcggg cagcacccgc gcctcggcct gccgtacgtc gtcaaagacg
     9661 gtgcgggtgg actccaccct tccctccttc gggccgtccg tcggggtgcg ggagcgaccg
     9721 cccgcggcgt gtgggcgctc ccgctgcgcg cccgcacgcc acggtgccgg gacctgcgtc
     9781 agttgccgac gctgttgctg gcgttcgtcg tctcgatctt gtcgagcagc cggattgtga
     9841 tcttcgtctt gaccggtgcg gccgcctcgt ccgcggtctc gagctccgac tcgttggggt
     9901 tcatccggtt cctctcttgg gtgaggggtc tcgcgagaac gcgttcagca ttcgccgccg
     9961 ccgccacgca gtcaaggatt ctgtcaattc cttctggtaa tcactgtttc ggtcgggccg
    10021 gggaaatgcg ctccgtcgaa tcgaaacggg cgcgtgcccg agtcccgcag accgggcagc
    10081 cgggacgggg cggatggctg acccacacgt ggtggtcccc ggcgatcagg ttgactcccc
    10141 ggatgacgcc gaccggcggc gcggacaccc cggtcagcag cccgatcagc gcgtgggcga
    10201 cgaactggcc ggacagaccc gccgatgtgg cgatcacccc cggcccgccg aggtcgaccg
    10261 gcgtacccgg gcggcgccgc gcctcctcgc cgtcgcacag gcactcgtag caggtgccgg
    10321 cccccggcgt gaagcagccc acggtgacca gcgggccgct gtatccgcca cccacccacg
    10381 ggatccgggc cgcggcgcag gcgcggttgg cccacaccct gatgccgtgc ccgtccggcc
    10441 ggtccgcgca gagggcgagc gcgtcgtagc ccgcgatcag cgtgtcgagt tcgcggcggc
    10501 tgccgatgcg ccgccggtcg ccggtgacag tgatgtcgga gttgacgcca cgcagccgcg
    10561 cgacggccgc ctccgacttc ggccgtccca cgtcggcctc gccgtacagc acctggcggt
    10621 tgaggttcga cagctcgacc aggtcggggt ccacgcagtg gatctcaccg acgcccgcgg
    10681 cggcgagggc ccacgccgcg tggctgcccg tgccgcccag ccccagcacc accacccgcg
    10741 cgctcttgag ccggagctgg acctcccagc tgtgcgggcc cggcccgacc acccggaaga
    10801 acgcctggtt cctgctgtac cggtcgagct cccgctcgct cagcgcggcg ggcggcacgg
    10861 cggcggcgtc ctccacgtat cgggtctcga cgagctgctc gacgaccgac tcggcgtccg
    10921 gcagctccgg atgggccgag cggagccggt cggcgatgtc ctcgcgggag cgggtgccgt
    10981 ccatcaggca cagggcggtc cagacccaac cgcgggggtc ctcgatttcg gcggcgatcc
    11041 cgtgaatctc gccgccgatg cgaatggtgc cgtcctcgta ccggtggggc cggtgctcga
    11101 atttcacccg gggcaggcgc acgagtcgag cattactgcc cggtcactta tccggtcaac
    11161 acccgaatcg gcgcaatcgg gatatggggt gcggccggaa agggttacgg ccagctcttt
    11221 ctctcccgtc gccgccgcct gccgggggac ggcggcgcgc ggcgtccggc gtcgaagagg
    11281 acaggaaagg gcgccgccgg gcatacgttg gaagacgatg aacgatcagc gtgcccgtac
    11341 cagtcgtgtc ccgttcctcc ccgcgtcgcg gcgtccgcgc gtgctcgccg gcctgctcgc
    11401 cgccgggctc gccggactgg tctcgctgtc cggctgcgcc ggcgcgcggg gtgagggatc
    11461 gccggcggtc tccggcgggg ccgaggctcc ggccgcctcc gcgacgccgc cggagcggcc
    11521 ttccggagac ccgtccgcac cggtgaagcc ggaccagtcg ccgtcggcgg agccgcccgc
    11581 gcccgatgcg aagatcccca aggaccccgc cgcgctggcc gcggcgctga cccggacgac
    11641 cgcgctgctg cgggacgccg tcgacgactg gaggcgcgag ggagaccccg ccaagggaca
    11701 ggcccccgag cccgtggtcc tgctctccct gtacgagcag cgcctcttcc gtcatctggc
    11761 ccgcaacccc ggcgtcgcgt cccgcaccta cggcaggctg ccgaaggacc aggccgcgcg
    11821 ggcgcgcgac aacgtgacgg ccatccgcga cctgctgtcc ctcgcccacc ccgtgagcgg
    11881 gccggtgaag ttccgcatcg agccgccgga accggcggac gtcctgctcg agggcttccg
    11941 ccgggccggg cgccggttcg ggatcgactg gcaggtgctg gccgcggtca tgctggtgga
    12001 gacgaagttc ggccgggtcc ggtcgccgag ctacgtgggc gccaaggggc cgatgcagtt
    12061 catgcccggc acctggaagg cgtacgggat gggcggcgac atcgaggaca ccacggacgc
    12121 cctgctcgcc gcggcgaact acctgcacgc gtccggggcg ccgggcgact accggcgggc
    12181 gctgtacgcc tacaaccact cccaggcgta cgtcgacgcc gtcctgctgc acgcccgcca
    12241 gatgaagcgg gacatcagga actactacgc ctactacacc tggcaggtgt acgtgatcac
    12301 gacgaagggc gagcggcgcc tgagcggccc ctgaccgcgg ggccgggatc cacctttggc
    12361 cttgactcga tgtaaccaat gccgccttcc gagcgactga tcctttgggg cccgatcgcg
    12421 gcagggaggc cggctgtgcg gtggatgacg gctgtcatgg ggacgacgcg cgtcgcggtg
    12481 gcgctcggag ccgccgccct gacctcggtg ctcctcgcgg cgacggccct cggcccgcgc
    12541 ccggcgctcg ccgccgccgc accgtgcgcg tcgggcgctc cggcgtccgc ctggatcgag
    12601 acgtccgtga ccgtcgagga acgcggccac gacaccgccg tgctgaggag caccacgtgg
    12661 gtcggcgtgc cccgtgactg ggcgggggcc gccgccctgc tcggcgcgac caccacggac
    12721 ggctgcctgc ttccggaagg cggctcgtcg agcgccacga tgtcgccgga cggcgccgag
    12781 gtcgtggtcc ggcacacgga ggagactcct gtgcagttgt acggtgcgga gtggatcggg
    12841 gagcccgccg ggctgtggtc gagtcgcacg tccggccgga cctgctacgt cgcgctgctg
    12901 cccgcaccgg ccgatctgcc gcccgggctg gccaaggcca ggtggcgggc cgtggccgtg
    12961 cgggcgccgg actccggggt gcgcggagtg cagcccctgc cgtcggaggt gcggcccgac
    13021 cacacgtacg tgtggcggga cgccgccgcc ccgccgcgcg tcgaggtggc cctccggatg
    13081 tccgcgcggt ccgagttcca gcgctgggcc ggctcgcggg gggcggacgt gctcacggtc
    13141 gtgacctacc tgggtttcgc gctgccgtac ctgctgccgg ccgtcctgct cgtgctgctt
    13201 cgccggcgct cggccgaccc gggcgagcgc gcgctcgccg ggatcatgct cggcgcgctg
    13261 gcgttgatca ccgcggtgga gacgatcacg gccgtcctcg tcctcagcgg gactgcgttc
    13321 gcggcccacc tcctcggcct gacggacgtg ggggcgatcg tcatcctggc ggcgccgctc
    13381 tgcgcggccg cgtggcggtc ggcacgtcgg cgaatccggc gccccggccc tgtgtccacc
    13441 ggccctgtgt cgcctgatgc ggggcccacc ggctcagggc tcgacacgct gagcgctccg
    13501 gcgttcggcg gcgtggtgct cgcgggagtg gcgctcgtcg ccgtcagcgg cttcggaccc
    13561 ctggccgtgc ggcacgccga cgaacagccg gatctgatcc tgccggcgtc ggcggtcgcg
    13621 acggcgttgc tactcaccgg tgcggcgtgg gtgatcgcgg tgcgggcggc ccgtgtgccg
    13681 gacaggagga cgccccgggc cgtccgcacg ctgctgcaat ggagcgtccc ggggctcgcg
    13741 ctgctcacct tggggttcgt ggcccacgcg gccgccaccg gcctgctggg gttctgggga
    13801 aatctgccgc gcgtcgtcgg gtcgccattc ttcctgctgg aaaacctcgc gtacctgatg
    13861 tggccgctgg tggtgctcct gcttctgctg ctgctgcgcc tgtacgggcg gcgcacggac
    13921 accgtcgggc cgctcaccgc gtggctcgtc gtcttcctgt tcgtcgtggg cacgatcagg
    13981 tggcccagca cgtacgcggg gatgcccgtc ccgctcgccg cgctcaccgg cctgacggtg
    14041 ctgcccctgc tgctgcggct gacgcgacgg gccgagcccc cggacccggg cgtgtcgcgg
    14101 cggcggctcg ccgtgatcgt cgaggagcac cgaaccctgg aggcccggga gaagggcctg
    14161 cgccggcgct gggccgcggg cgacatggac gacgccgcct accacaggga gaacgagccg
    14221 gtcgtggacc gcatcgggcg gttacgcggg gagatcggcc tcgatccccg cagggaggac
    14281 ggcctgaccc cgctcgacct cgcgctgtcg cgcggcccgg ggggctcgtg gtgggccaac
    14341 gcgcggctcg cctcgcggta cgcgtcctac gtgggcgcgc ccgccgccgt cttcctcatc
    14401 tgggccacct ggagcgcaga cagcacgggc cacgacggct ggctcgaccg gctccgcgag
    14461 cccaacgggt tctacgggct ggccggcgac ctgatcggag gtctgctgat ctggccggtc
    14521 gccgggttcg tgctgggcgc gctgtggcgt cggctgcccg gcaggcgcgg atacctcaag
    14581 ggggtcgtgc cggtgctcgc gtacggcgcg gccacggggg cgcacgcgat gctgaacaac
    14641 ctcatcggcc aggctcccgt gcgcggctct ctggtccggg tcctgctgct cttcctggtc
    14701 ctgaccgtgg tcgccgtcct catggacgcg cgcacgctgc agacccgtcc gggcggcctc
    14761 gcgtcgcggc tcacccccgt ggccgtcgtc taccggctcg gtacggcggg cagcgggatc
    14821 gcgctcatcg tcgcccaggc ggcggcgatc ctcggcctgt ggacccagct caggcacggc
    14881 atcgacatca cctcccaggt cgacacctcg acgcaggcgc cgccgagcac cgacgcccag
    14941 ctgttccaga gccggccggg cggataaccg cccggccttc gcggcggggg cgccggagcg
    15001 tgctcagagc gcggggtagg cgttgttcac cagcatcacg aactgctcgt ggtgccagtc
    15061 gccgtagagc ggcgcgttgg gaagggcgtt ggtcggccgt atcgtgtccg accagggcgt
    15121 gaggttgccc ttggggtcgc acacgcggtc gaccagccgg tccgagccct cgggcagaat
    15181 cggcccgccc gctccgtccg actcgccggg ccgcttgatc cacaggtagg cgtcgacccc
    15241 gggaaccggc gccgcgaccg gccgcgcgcc cagccccgcg ccgttctggt tgcaggtggc
    15301 gagccgcgac gggcgccggt cgacgcggct ctggtccacg tacgtgttga ggtcgagcga
    15361 ggtgctcacg gccgtgggcc tgcccggccc gccccagccg tcgcgggagg tgtcgatcac
    15421 cacgccgagc gagctcggca ggcccttggc gacgagggcg gcgcgtatcg cgagggcgta
    15481 gtcccgctcg tcgaagtgcg ggttccagtc gtagaacctg ctcatgatga gctgctggcc
    15541 ggccacggtg tgggtggggt cgggcaggaa cggttccgtg agggggacgt agtcggcgac
    15601 gttcgtggcg atgccgtcga ggctgtgcat ccccgccgcc gtgccgcgca cggtctcggt
    15661 gatgagggtc gtcagctgcg tgaagttggt gtcccagccc gcgagcgacg cgttggcggc
    15721 gtccaggtac gtgtagacgt tgggcagggg cgagagcctg ttgagggcgt actggatgcc
    15781 cgtcaggtac acgcccgact gctgcgcctg ctggcacggg aagatccccg cgctcacgcc
    15841 cacgatgagg tcgatcagcg ctttcggttc gacgacggtc gcgacgcgga ggttccggta
    15901 ctcgggcctg gccaggacgg cggcgatggc gtcgacgtac tcggtcctgt agcggttcag
    15961 gccgccctgc gcctcgtgca gttcggcgct ggagaccagc gaccggcagt cgcggtcggg
    16021 caggtcgtgc agcacgagcg tgacgtagcc ggcgttctgc cgtacggcct cgtcgaggtg
    16081 gtccttgagg gttctcgtca cgccggggcc cccggtgacg tcggcgatgc ggtcgagcca
    16141 caccgcggtg gacgtcgtct tcaggccgcg catcttggcc gcggtcgcgt cgtccacctt
    16201 cgcggccgag gactccacgt cggccgccca gtccgggtcg acgtacccgg tggcgccggt
    16261 gaacgggttg tccaccggca cgtccgggct cgggctgacg ctcgggctcg gcgaggggct
    16321 gggcgagggg ctcggtgacg ggctgggcga ggggctccgg ctggggccgg cggacgggct
    16381 ggcggatgcg ctcggcgacg ggctcggaac aagggtcacc tggcacggca ccccgttcac
    16441 ggcgaagtca gtgggcggcg ggttgcttcc ggtccaggcc ccgttgaagc cgaggtggac
    16501 ggatccgccg gagggcagcg tgccgttcca ggcctcgttc tccgcgacga cgtgctcggc
    16561 gagttgcgtc cacctggccg accagccctg cgtgagccgc tgggagccgg ggaacgagaa
    16621 cgtcagcctc cagccgttca gcgactcgcc ggtgctcgtg acggtgacgc cggccgtgaa
    16681 gccgcccgag ttcgtgcccc attgggtggt cgcgtaggtc acttcgcagc cgaccgcggc
    16741 gtcggcggag gtcgtgccga ggacgagccc cgccccgccc agggccgtgg cggtgacggc
    16801 cgtcaggagg ccgcgaagaa accggttgtc gccgaatgcc atgggccgtc cttctccggg
    16861 tgaggtgacc gggcctgtcc ggcggccgct ccgcatcccg gaggggcgcc gacgatctcc
    16921 agagtccgtg atggcccggg tcgtgtacac cggtccgcgt gaggggaaac gtccctttcc
    16981 gcaatgggcg gacgagaacg tgaggagacc tcggagaatc cgtacgaggc cgctgcctgc
    17041 ccctgccgga cgcggtgaaa tattcagcgg ccggcgcccg tgggcccggc cgtcagggct
    17101 tgcggccgac gccgcagaac gaggccaccg cgcggggacc gctttccacg tcagcgacgt
    17161 cgggccgcca gcgggaggtg gtgaccacgc cggggtcgac gagctccagg ccgtcgaaga
    17221 agccggcgat cgcctcgggg gtgcgcaggt ggtaggaact cgcggagttg gcgttgtaga
    17281 cctcgatggc ccgcacgagc gcctcgctgg tgtcggtgcc gtcgctcacc gccagatagc
    17341 tgccggacgg cagggcgtcg agcaggcggg ccgcgaccgc tcccgggttc tcctcgtcgc
    17401 gaagctggcc caggatcccg agcatcatca gcgcgacggg ccggtcgaag tcgagcgtgt
    17461 tccgggcggt ggccaggatc gtgtccgtgt cgcgcacgtc ggcctcgatg taggcggtcc
    17521 tgccctccgg cgtgctggtg agcagcaccc gcgcgtgcac caggacgagc gggtcgttgt
    17581 cgacgtagac gatccggcta tccggggcga cgcgctgggc gacctggtgg gtgttgtcgg
    17641 cggtcggcag accggtgccg atgtcgagga actggcgtac gccggcctcg gcggtcaggt
    17701 agcgcaccgc gcggacgagg aaaccgcgct gctgccgggc gatccgggcg atgtcgggga
    17761 acatccggag gatcatgtcg ccgtcctcgc ggtccacggc gtagtggtcc ttgccaccca
    17821 ggaggtagtt ccagacgcgg gccgagtgtg aggcggagga gtcgatcgcg ggggatcctg
    17881 gtccgtcggt caccgtggtt ctccggtctg ccgtgccgat cgagatcatc agtctcgcgc
    17941 cggtggtcga gatgcgcaat atgtgacgtc tgtgacgatt gatacttctg ggattaggcg
    18001 cgatcacccg gggcagtgcg gacgccatgg gcatcctgac ctctcccggc gggcgggccg
    18061 ccggtgcttc cgcgcgggcc ggaagcgtgc cggtgaacct cgacgtgcac ggcctccgga
    18121 aggagcaccg catctgcccc gactgcgtac gcgagctgtt cgacccgcgc gggcgcaggc
    18181 atctctaccc gctggtccgc tgtcgtgagt gcgggccgcc ggccggagag ccacgcgtac
    18241 ggccgcgcgc tctgtgcgag gactgccggc gcgagtgcga ccggcccggc tcgcggcgcg
    18301 gtccgggcga cgcggcggga tgcgcggcct gcggccccgc cctgcgctgg gacggcctgc
    18361 tgggccagga cgcgctggcg aaggcggtcg aggtgatcgg ggccggggga gtcgtggcgc
    18421 tcagggacgg cttcgccgac cagatcgtct gcgacgccgg ggcagagccc gcgctcgccc
    18481 ggatggacgg cgcgccgggt ccggtccgcg tgctcgtgcg gcacgtctcg gcggcccggg
    18541 agctggccaa cctgtccttc ctcgacatcc gcgcgctcgc cgggcgctcc cacccggcca
    18601 cgctggtccg gctgcgtgag ccgcggctgc ccagggcggt gcgccgggcg acgcccgacg
    18661 tcgacctctt cctgccgcgc actccgctgc agcacctgct cacctcacgg ttcgagggcc
    18721 cgctggccgt ctgggaccgt tgcgacgagc aggcgctgcc gtacgacggg acgctgaccg
    18781 tcggcctcga tctggacctc gaccacggat tcggccacgg attcgaccgt ggactcgatc
    18841 acgcgctgga tgttccggcg cggtcggtct ccccggcgcc gcggacgtcg tcgccggcgt
    18901 ggcccgtctg gacgtctccg cggcaggacg gcaggccgga cccgtcgtcc gctcctgcgt
    18961 ccgcccctgt gtcgaccccc gtgtcaccgc tcgcccagtg acgtgccggt gccgtggctc
    19021 gcggcaaaag ctgagtcatg atccatgacg cgctcggcat ggccggaacc gaggtcgccg
    19081 gacggggtat gagggcatcg ttgcccatgt ccacgacgag gcccatcacc ggatggcctt
    19141 ggtgagtagg tgcgtttcca gatgtcccgc gactgtgcgc cccaggtgcg aacggtgccg
    19201 gcgctcgcgg ccggccgcct gacactggcc gccctcgcgg ccgcgctcgc ctcggccgcc
    19261 gtctcggtcg ccgcttcggt cgccaccgcg ggggaggcga gcgcgagcac gccgccgctg
    19321 cgccgcggag tcgcggcgta cgccgccggg cacggaaacg gacacggggg cggcggaggt
    19381 caggtggcgg ccggaggagt ggccacggcc aggcagttcg gctcggggaa cggcaaattc
    19441 aaccagaacc tcaacggcgt ctacagcccg accttcatga tgggccagca gcagaccggc
    19501 atcacggtcg gcggccgtat caacacccag ggcgccttct gcggccccgg cccgaggcac
    19561 tgcaagatct ggcagaacat gccggtcaac gccatcggct ggtgacgtgt cccgccgtgt
    19621 gatcagatcg ggtgccacgg aaatggcaat gatggcgtaa gacgccgcgc gtgccgggcg
    19681 ccgggaaaag gtggatcact agcctgagga tcggcccgca cgaggaaggg ccgcaggagc
    19741 ggtccggctg acgggagcgg cgcgcgatga ggtgtcggtg gtacggcagg ccggttctgc
    19801 cgagcggttc gggacttgtc gcctgtgtgt cgatcgcgct gactctcgcc accgcggcgc
    19861 ccgccgccgc aggcggtcta tcgcgtcatt cgccggggcc acagccggat cggggagcat
    19921 cggcggggag ggaggaggcg cagcccgcgc tctccgcgtc gagccccatc agcaaccggg
    19981 gcacccagca ggtctccgtc aatgtcgcga acgaggggat cggcatccag aacgcgttgt
    20041 gccgggggag ccgggcgtgc gacatcgccc aggtgctcgc cgtgccttcc ggggaggacc
    20101 cgcccgccgg gcgccccgcc ccgaaagcga tctcccgccc caaggccctc gcccgccgcg
    20161 ccgcacgcac cctgacgcgc gggatggcgc gcagaatgcc acgcgggatg tcacgcggga
    20221 tgtcacgcac ccccgcccag gccggaagaa acccgtcccg cgcctcggga taggccctgg
    20281 tcgtaccgcg cccgcggcgc gctgtggggc gcgccgcggg cagggtgcag ggcggggtgc
    20341 gtcagctggt gtacgcgcag atggcgtaga cgctgatgcc cacgctgtcg tagcgggtct
    20401 gccggccgag ggcgatccag ccggtgccgt cggccgtggg gaagctgccc acgaggaccg
    20461 cgtcgttgcc ctgtgcctcg ccgccgccgc cgacggcccg cttgccggcc gggcagtaca
    20521 cggtgcgccg ggtgaagttc ggcacgttcg cgttgggcag cgtgacgatc tggtagccgg
    20581 cgaacgccga gtccgagggg tccgtcggcc cggtgccggc cagcgcggcc gcgctcgtgc
    20641 ccgtcagccc ggcgagaacc agggcgcctg ttgtgactgc gtgaacaaat cgcacgtaaa
    20701 agctccgttg tgttgagaat gaccggattt ggaccgagga aaatgggttt gaatggcgga
    20761 aggccgtccc cttcggttcc gggaccacac gtacccgcga tcttcatcga ccacactcgg
    20821 caatgtgctg tttacacaac gtggcgactt cgccgatctc acgatgacgc gaggtcacgg
    20881 ccgtcctatg tggtcccgtg tggtccgtgg aggcacctgg ggcgggtggt cgcccgtggg
    20941 tacgttcctc ctcgggggga tcgcatgaga aagatcgtcg ctgtctccgt gctcgccgcc
    21001 atgacgacgc tcggcacggc cgccgcggtc gcggcggtcg ccgccgggac cggcgtacgc
    21061 cccgggaccg gcccgcggag cgcgtaccgg caggctccca cgctgcccga gggagggatc
    21121 ga
//
