LOCUS       NZ_VYTZ01000007        24883 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold7, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000007
VERSION     NZ_VYTZ01000007.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 604610)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 604610)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 128327
            Orig. end                         :: 153210
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000007.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24883
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..24883
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24883
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14883](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..14883)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    359..374
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.22"
                     /tool="antismash"
     gene            507..1304
                     /locus_tag="F5972_RS20405"
                     /old_locus_tag="F5972_20405"
     CDS             507..1304
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="F5972_RS20405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20405"
                     /product="ABC transporter permease"
                     /protein_id="WP_150935193.1"
                     /transl_table=11
                     /translation="MNDVAQAVRLARVDLTLVFRNRTAFVNAVLLPLLIAGALASNGVG
                     GGTGGIPATQYVMTGMMAFILIFATFMNLAGFYTSRREEMVLKRLLGGPATRTAILGGS
                     ALGATAVYLGQVLILCALMSAVMGTGAPADVPLLLLAALLGAAFFSLLAMAVSGLSSTG
                     EMAQIATLPVVLLLVGGSPVMLPPEMLPQALRTVIEFLPMTPIVEIMRTAYLGLDYIGA
                     GHEPLGALERWSAALPSLGLLAVWIAVAALMARAFFRWDPRRG"
     gene            1321..2523
                     /locus_tag="F5972_RS20410"
                     /old_locus_tag="F5972_20410"
     CDS             1321..2523
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1048: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF019350.5"
                     /locus_tag="F5972_RS20410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20410"
                     /product="sensor histidine kinase"
                     /protein_id="WP_150935194.1"
                     /transl_table=11
                     /translation="MNAGIKRARHITFWTLALELVFAWLGPVIQIVVEIRTEGGVGWSR
                     LVLVAVGLPVFSWLFLRVVRAAVDGRPAVREVVVSGALALTMMVLGAVLVADVPGVASA
                     MLPFSWSTLTTTWTAVAVLGVSARTAVALTAGAAGVYVALDFLLLPGVGDQRTDLFFYL
                     PMLALLPYSNRLWLWIYRMIIQVDEGRKAQAELAVTEERLRFARDLHDLVGHSLSAIAV
                     KSELAVKLARAAPDQATEEMTAVRGLAKDALKEIREAVRGYRAIDLSAELGSVRAVLEA
                     ANIRCTLDLPERTPPGEAATLLAWVVREGATNTLRHSAATRSRVTLRLTGGTAVLEMVN
                     DGVGEQSAADGGTGLIGLSERLAAAGGSLTARPTGSGEFVLRAVVPATDRAHVLTEAVA
                     R"
     gene            2532..3125
                     /locus_tag="F5972_RS20415"
                     /old_locus_tag="F5972_20415"
     CDS             2532..3125
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573094.1"
                     /locus_tag="F5972_RS20415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20415"
                     /product="response regulator transcription factor"
                     /protein_id="WP_150935195.1"
                     /transl_table=11
                     /translation="MIRILLADDEHLIRGAIATLLGLEPDLEVVAQVSRGDEVAPAVRE
                     HRPDVVVLDIEMPGMDGLTAAEGLPGQAMIILSSFGRPGYLRRALAAGVRGFIPKDASA
                     DELATAIRKVHAGGRYLDPEMAASAMMAGDNPLTDRERGALALAAEGASVRQIATALHL
                     TEGTVRNYLSSAIAKLGATNRITAIRAAQEKGWL"
     gene            complement(3085..4044)
                     /locus_tag="F5972_RS20420"
                     /old_locus_tag="F5972_20420"
     CDS             complement(3085..4044)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS20420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_20420"
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="WP_191910233.1"
                     /transl_table=11
                     /translation="MTGHEFTLTATGPFDFGATLRFVEDWPATSGLPSDGRTLRFAYCA
                     EADWLPIGVTVTAAPGGVAVRTTRAAGPDVRGEVARILSLDVDGSGFAEIGESDPVLGE
                     LQRRSPGLRPLCFWSPWEAACWAVIVQRSSMLVASRLKQRIAERYGATVDLDGRAYAAF
                     PPPVSLLNADGLGLPEQKEEWLRGLARAALDGVLTTEHLRALDPPEALAELRALPGVGP
                     FSAGLILIRGAGAPDAFPGDEPRLFAILREAYELPPDAPASAYRKVADAWRPYRSWASF
                     LFRSSAYGVREDQRAGAAAAQAGKDVRASLSPGRRGSR"
     misc_feature    complement(4147..4159)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 20.45"
                     /tool="antismash"
     gene            complement(4156..5601)
                     /locus_tag="F5972_RS20425"
                     /old_locus_tag="F5972_20425"
     CDS             complement(4156..5601)
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011293346.1"
                     /locus_tag="F5972_RS20425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20425"
                     /product="endo-1,4-beta-xylanase"
                     /protein_id="WP_150935196.1"
                     /transl_table=11
                     /translation="MKPPNTGTERHRTRARGPATALAAIAAATAVALNLAIPAQAASTL
                     KAAAEARGRYFGTALTRGDLGISAEVNLAAAQFDMVTPGNEMKWDATEPSKGSFNFGSG
                     DQIVSFAQSHGMRVRGHNLVWHAQLPAWVGGVPLNQVQGVMENHITTEATHYRGKVYAW
                     DVVNEPYNEDGTLRQDVFYKAMGSGYIAAALRAAHAADPNAKLYINDYNIEGINAKSNG
                     LYSLAQSLLAQGVPLHGIGLESHFIVGQVPSSLQANMERFAALGLDVAITELDDRIQMP
                     ADSSELQQQGTDYGRVVNACLAVPRCVGVSQWGVDDGHTWIPGTFPGYGAPMMWDSSYQ
                     PKPAYQAALSALNSGTSSPSQSPSQSPSQSPLSSPSSSPSSPVPGACSATIKTINSWGG
                     GFQSEVTVRAGSSAVNGWTVKWAWPGGQSISSLWNGVSSGSGSSVTVRNESYNGSVAAG
                     ASTTFGFTANGAAATPTATCTSP"
     misc_feature    complement(5578..5594)
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: weak, score: 21.74"
                     /tool="antismash"
     misc_feature    complement(5858..5871)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.31"
                     /tool="antismash"
     gene            complement(5958..6812)
                     /locus_tag="F5972_RS20430"
                     /old_locus_tag="F5972_20430"
     CDS             complement(5958..6812)
                     /EC_number="2.8.2.-"
                     /GO_function="GO:0008146 - sulfotransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050656 - 3'-phosphoadenosine
                     5'-phosphosulfate binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (extras)
                     Sulfotransfer_3: Sulfotransferase domain"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540199.1"
                     /locus_tag="F5972_RS20430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20430"
                     /product="sulfotransferase"
                     /protein_id="WP_150935197.1"
                     /transl_table=11
                     /translation="MPWKSKVNAAVEGMTGYVITRARPRPAQVQPPRDEPRPPADPEID
                     RLLRAPVFVLSPVRSGSTLFRVLLNSHSRIHAPHELHVRRIAVTLTTEPVRQAMEAAGH
                     STSDIEHILWDRLLHRELVRSGKEIVVDKTPSNVFAHRRITTCWPDARFVYLLRHPASI
                     VRSWHEADPQARPVEEAVRHTLQYMRYLEESRRRHEGLVVRYESLVDDTEGELRRVCAW
                     LGVEYEPEMIRYGDKDHGEFVKGIGDWRDKIRSGRVQRGRPLPPPEEVAEPLREIAAAW
                     GYL"
     gene            complement(6984..7520)
                     /locus_tag="F5972_RS20435"
                     /old_locus_tag="F5972_20435"
     CDS             complement(6984..7520)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS20435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_20435"
                     /product="hypothetical protein"
                     /protein_id="WP_150935198.1"
                     /transl_table=11
                     /translation="MRGASGAFVLAGRIGLVAVPAIVLSTACGASEPGTRSRPEATPAA
                     VSTTMSTTVPVPSATPAPAALPAAADPEACRNADCEVEVRQGDRLRLDAATGLDALTVA
                     ALDQGVVRLRFEGSSGGYRVEGMNVGVSQDCVNGRCRTRGALTLTMDRPARIGDIHLRL
                     TSVRPDEAVLAISPS"
     gene            complement(7646..8527)
                     /locus_tag="F5972_RS20440"
                     /old_locus_tag="F5972_20440"
     CDS             complement(7646..8527)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF013757.5"
                     /locus_tag="F5972_RS20440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20440"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_191910234.1"
                     /transl_table=11
                     /translation="MIVLMERSGRAETASALGSLERGIAILFCLAVGMRPMNLTQVHRS
                     TGFSKTTTHRLLGVLQGRGLVTRRGGDYTVDGRFAELLTPRGWPVQGRRVPDCRRAVLP
                     YLLQLYEATRQTVNLAVPDRGEVAYVERLYGHNRVTSPSDGLDRAPLHCTAAGKALLAH
                     DAALRKAFYAGPAPRRMTGRTVTGPAALERELAAVRVEGVSYAREEFAEGICCAAAPVF
                     GPDGRVCMAVSVAAPAGAAALPRLGPAVRRTAHQITEVLGTILAPGPERTGPVFGRVPA
                     PTGNARRTAVRQ"
     gene            complement(8652..10004)
                     /locus_tag="F5972_RS20445"
                     /old_locus_tag="F5972_20445"
     CDS             complement(8652..10004)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017541264.1"
                     /locus_tag="F5972_RS20445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20445"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_150935200.1"
                     /transl_table=11
                     /translation="MSAPLGPDGASRLALSTRAARTLATTTKTPPQMREITPRHLLRVL
                     PWIDVQGGVYRVNRRLTYTPGDGRVTFVSTGAEVRVIPAELCELPSLHGYADADVLAAL
                     ADRFVQHELEPDEPVPAGQVVLVAHGKIACVGVGEYGGETLLRVVADGDHLGDLTGPAA
                     APAKALTRCIVLVLERPVVEELTERSGSLREQLNRPAAGRPVNRYGEAEIALAAGHVGE
                     ATLPGTFVDYELGPREYELSVAQTILRVHSRVADLYNEPMNQTEQQLRLTIEALRERQE
                     HELVNNRDFGLLHNADLKQRIHTRSGPPTPDDLDELLSRRRSSHYFLAHPRAIAAFGRQ
                     CTARSLYPDVTEAGGAKVMAWRGVPILPCDKIPVTDRGLTSILVMRTGTEKQGVVGLRR
                     TGLPDEYEPGLSVRFTGIDDKAVISYLVTTYHSAAVLVPDALGVLESVEVG"
     gene            complement(10001..12223)
                     /locus_tag="F5972_RS20450"
                     /old_locus_tag="F5972_20450"
     CDS             complement(10001..12223)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017594229.1"
                     /locus_tag="F5972_RS20450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20450"
                     /product="terpene synthase family protein"
                     /protein_id="WP_225311683.1"
                     /sec_met_domain="T1TS (E-value: 1.5e-80, bitscore: 266.7,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSYRLPDFYLPYPPRLNPHVETARTHTRGWAGQMGMLDDPDIWT
                     EESLDAMDYGLMCAYTHPDCSAPELDLVTDWYVWVFFFDDHFLETFKRGRDLGGAQEYL
                     DRLDAFMSDDPPEAANPVERGLADLWPRTVPAMSAAWRRRFVRVTRDLLQESMWELFHI
                     ERDAVSNPIEYIEERRKVGGAPWSAALVEHAAGAELPARLAGSRPIRVLTQSFADSVHL
                     RNDLFSYEREVREEGELSNCVLVCERFFGCDTERAVEITNDLLTSRLHQFEHTALTELP
                     ALFADEAVSPPEQGLVLRYAKGLQDWQAGGHAWHSASSRYTKNGGQAGIFGMNVSRAHV
                     TGAGGLRNHTHRPFAEADVRLPEPYMPFEVRDNPHLDAARAADLEWCAAMGFFDGVPGI
                     PATAVWDERRLAGFDLALCASGITPDATADELVLATNWLAWGTYGDDYYPRVFGAARDL
                     VGAKLLNRRLKELMPLDLVPRLTPLTGLERGLADLWPRTAGPLPPGSREIFRTSVEEMI
                     DSWVWELANEAQHRVPDPVDYLEMRRATFGSGMTMSLARLAPGRVIPEEIILTREFLGM
                     TDAAQDYACLLNDLFSYRKEIRYEGELHNAVLVMSTFLDCPPQEGVTVVDGLMTSRMRQ
                     FEHITTVDLPALLDRIDAGEAVRESVAAYVTDLRNWMAAILRWHQRSRRYLDEELRAGP
                     VARWTQGPTGLGTATARIGSLASAYGGPAGDGVAPAPVLHLTAGAS"
     gene            complement(12223..13623)
                     /locus_tag="F5972_RS20455"
                     /old_locus_tag="F5972_20455"
     CDS             complement(12223..13623)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017619264.1"
                     /locus_tag="F5972_RS20455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20455"
                     /product="family 2B encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_225311684.1"
                     /transl_table=11
                     /translation="MTETTPQTSAPNDSRLSLSTRAARNLATTTKTPPQMQEITSRHLL
                     RVLPWIEAIGGVYRVNRRLTYQVADGRVTFVSTGAEVRVISAELCELPALRGFGDADVL
                     ASLGDLFTQREYEAGQVIAAAGAPMEEVVLLAHGKVDKIGEGAYGNETLLGVLADGEYV
                     GEQMLVHPDARWEWTVRTVTPCTVLALTRDAFERLLALSESLREHVSAYREDPDGPVNR
                     YGEAEIALAAGHVGEATLPGTFVDYELGPREYELSVAQTILRVHSRVADLYNEPMNQTE
                     QQLRLTIEALRERQEHELVNNRDFGLLHNADLKQRIHTRSGPPTPDDLDELLTTVWKNP
                     TVMFAHPKAIAAFARQCNSRGIYPQTVEFNGQKAPAWRGVPLLPCNKIPVNGQGVSSIM
                     VMRLGEKDQGVVGLRRTGLVDEYEPGLSVRFMGIDDKAIISYLVTTYYSAAVLVPDALG
                     ILESVEVL"
     gene            complement(13807..14883)
                     /locus_tag="F5972_RS20460"
                     /old_locus_tag="F5972_20460"
     CDS             complement(13807..14883)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012853353.1"
                     /locus_tag="F5972_RS20460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20460"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_150935201.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 2e-51, bitscore:
                     169.8, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAEIVDTSITGITGRVRRRVDELLSDFLDARRPPVGDHDVAEGY
                     RLLREFVVKGGKRVRPLLCYWGWRGAGGEELREAAVVATGAALELYHAGLLIHDDLMDG
                     SELRRGRPTIHRGLARPGRFGAAEQFGQSAAILLGVLAQAWAEELLADAGPADVRARAA
                     RDLFNRMRTEVVTGQYLDLLAHARGDDGVEQALTVIRYKTARYTVERPLQIGAALAGAP
                     PSLLDAYSRFGLPLGEAFQLRDDVLGVFGDPSVTGKPVLDDLREGKRTVLMAYASARAR
                     GPERDLLRTWHGDPALDEARAAELRRIIVDTGALDRVEELITQRTGQALAALRDCPITP
                     EAAEALAVLTERLTRRVR"
     gene            complement(15079..16080)
                     /locus_tag="F5972_RS20465"
                     /old_locus_tag="F5972_20465"
     CDS             complement(15079..16080)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888972.1"
                     /locus_tag="F5972_RS20465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20465"
                     /product="pirin family protein"
                     /protein_id="WP_225311685.1"
                     /transl_table=11
                     /translation="MTAGPLSRGEGEPALYGGTVLNCSTGAAEAMPESVLLPGHDVPLG
                     RYTTVRRLLPQRPRRMVGAWCFVDHFGPDDVRGRPGMRVPPHPHTGLQTVTWLAEGEIL
                     HRDSLGNTQPIVPGQLNLMTAAHGIAHSEQSPPDHPPEMHGLQLWVALPEDARHGEARF
                     EHHAALPVLRDGNVTVTVVVGEVGAARSPARAHTPLLGAEVLFGGPGRHRLPVDPAFET
                     AVLAMSGTAEVAGAALSPGSLLYLGQGRADVPLETTGPARLFVLGGTPFEEPLVMWWNF
                     VGRTHEEIAAARDDWARGARFGVVPGGQEPLPAPEMPTVRLKARDRHGHRLP"
     gene            complement(16077..16412)
                     /locus_tag="F5972_RS20470"
                     /old_locus_tag="F5972_20470"
     CDS             complement(16077..16412)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014911861.1"
                     /locus_tag="F5972_RS20470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20470"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_150935202.1"
                     /transl_table=11
                     /translation="MEQTDPKVADNPEARRFEITVDGVLAGFAAYGLDGQTISFTHTEI
                     DSAFEGRGLGSTLVRAALDAARDAGLSVLPYCPFVRRYIARHREYVDLVPADRRARFSL
                     DGDEAAG"
     gene            complement(16437..17207)
                     /locus_tag="F5972_RS20475"
                     /old_locus_tag="F5972_20475"
     CDS             complement(16437..17207)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1208: pirin
                     domain-containing protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF014708.5"
                     /locus_tag="F5972_RS20475"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20475"
                     /product="pirin-like bicupin family protein"
                     /protein_id="WP_150935203.1"
                     /transl_table=11
                     /translation="MTTTRLTPRVDVRRAAERFSTRISWLDSRHSFSFGGHHDPGNTHH
                     GLLLVNNDDTVHPGTGFETHPHRDMEIVTWVLRGSLVHQDSEGHSGVIYPGLAQRMSAG
                     TGILHSEKNDSWRLTGGGAHDEPVHFVQMWVVPDEPGITPGYEQLEIEGDLLAGGLVPV
                     ASGMDKHDGAAAIRIKNRYAALYAARLETGQSVELPEAPFLHLFVPRGAVALEGAGMLE
                     TGDAVRFTATGGQKVTATEPAEILVWEMHATIAA"
     gene            17304..17807
                     /locus_tag="F5972_RS20480"
                     /old_locus_tag="F5972_20480"
     CDS             17304..17807
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1135: MarR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012888477.1"
                     /locus_tag="F5972_RS20480"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20480"
                     /product="MarR family winged helix-turn-helix
                     transcriptional regulator"
                     /protein_id="WP_150935204.1"
                     /transl_table=11
                     /translation="MNSPRWLDPDEQRAWRAYLRMQGRLTARLNRELQAGSGLSLADYE
                     VLVHLTDRADGRLRPFELERGLQWEQSRLSHHLTRMQRRGLVRREECAEDGRGAFVVIS
                     EQGRRAIAAAAPGHVETVRRLFFDGLTREQVAALEGLSADVLARLDDDNTDGHPGDDTD
                     DSLS"
     gene            complement(17800..18405)
                     /locus_tag="F5972_RS20485"
                     /old_locus_tag="F5972_20485"
     CDS             complement(17800..18405)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012780.5"
                     /locus_tag="F5972_RS20485"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20485"
                     /product="HPP family protein"
                     /protein_id="WP_191910235.1"
                     /transl_table=11
                     /translation="MLVHEIMTAPVVTVRRTATIRQAVRLLYEQEITAAPVVERPGRMV
                     GIVSEMDLLRGEFETDPRAFLRPEALPTGRPPALVEEVMTPRVATVGDAADVMDLLDLM
                     ITTGVKSVPVVRDDDLVGIVSRRDLMGLLVQGDERIRDDVLAALRDCADTAAFGAAVRS
                     GVVELYGPGDERAARIAEMVVRTVPGVAGVVFPEGLVS"
     gene            complement(18418..19542)
                     /locus_tag="F5972_RS20490"
                     /old_locus_tag="F5972_20490"
     CDS             complement(18418..19542)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131093.1"
                     /locus_tag="F5972_RS20490"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20490"
                     /product="CapA family protein"
                     /protein_id="WP_150935206.1"
                     /transl_table=11
                     /translation="MRSAAGDPVTLFLCGDVMLGRGVDQILPHPGDPALREPHVRDAGA
                     YVDLAEAANGPIPRPAACSWPWGDALEVLDEAAPDVRVLNLETSVTRSADFAPDKAVHY
                     RMNPANLPALTVARPDVCVLANNHVLDFGVRGLAETLDVLAEAGLGRAGAGRDEDEAWR
                     PAVVPLPGGGRVLVFAVAMPSSGVPGGWAARRDRPGVAFLPAPSPGCAAETVHHVRRAR
                     RPGDVVVVSVHWGSNWGYEVGDDQAGFAHALVDGGVDLVHGHSSHHPRPAEVYRDRLIL
                     YGCGDFIDDYEGITGYEEYRDDLRLLYFATVEAASGRLRELRMAPMRAVRMRLRHAGDE
                     DREWLRGTLDRIGRRFGARTGPAPGGTLVLAPAG"
     gene            complement(19661..20473)
                     /locus_tag="F5972_RS20495"
                     /old_locus_tag="F5972_20495"
     CDS             complement(19661..20473)
                     /EC_number="2.1.1.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: oMT (39-138). E-value: 1.1e-07. Score:
                     22.2. Matches aSDomain: nrpspksdomains_F5972_RS20495_oMT.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009074933.1"
                     /locus_tag="F5972_RS20495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20495"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_150935207.1"
                     /sec_met_domain="PCMT (E-value: 7.2e-12, bitscore: 40.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHESAVYTHGHHESVLRSHRWRTAANSAAYLLGALKPHMRVLDV
                     GCGPGTITADLAAYVPEGEVVGLDNAPAVVEQAREEAARRGVGNVSFTTGDVHALGSPD
                     ASFCVVHAHQVLQHVGDPVGALREMRRVTKPGGIVAARDSDYAGMIWYPLVPALDDWLD
                     LYHRVARANGGEPDAGRRLRSWAGEAGFAEITSSSSTWCFATPEDRAWWSGLWADRTLQ
                     SSYASRVIEGGHATQDDLRRISDGWREWGASADGWFSVVHGEILCRVG"
     aSDomain        complement(20060..20356)
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS20495_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="1.10E-07"
                     /label="F5972_RS20495_oMT.1"
                     /locus_tag="F5972_RS20495"
                     /protein_end="138"
                     /protein_start="39"
                     /score="22.2"
                     /tool="antismash"
                     /translation="MRVLDVGCGPGTITADLAAYVPEGEVVGLDNAPAVVEQAREEAAR
                     RGVGNVSFTTGDVHALGSPDASFCVVHAHQVLQHVGDPVGALREMRRVTKPGGI"
     misc_feature    20496..20505
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.9"
                     /tool="antismash"
     misc_feature    complement(20514..20528)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 19.7"
                     /tool="antismash"
     misc_feature    complement(20552..20563)
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 18.76"
                     /tool="antismash"
     gene            20591..21538
                     /locus_tag="F5972_RS20500"
                     /old_locus_tag="F5972_20500"
     CDS             20591..21538
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544719.1"
                     /locus_tag="F5972_RS20500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20500"
                     /product="DNA polymerase domain-containing protein"
                     /protein_id="WP_150935208.1"
                     /transl_table=11
                     /translation="MTSDEVRDGVTLTNLDQPLFDGAGAAKRDLVDYLDAVRDRIVPVL
                     RDRPLSVVRVRQGQAPFMQKNVPSYAPDWVRTVTVWAESSQRRVSYALCDDRRTLLWLA
                     NQRAVEYHPALVHAGHWDRPTHLVLDIDPPSAEAFPRAVGAARLVARALADAGLSGAVK
                     TSGAKGLHVFVPLEGETTEDVAAATRALGVRAERLDPALATTAFIREDRGDKVFVDSTR
                     SGGATVVAAYSPRVRPGVPVSFPVAWDDLDRITPGDFTVRTAARLLRDGDPWADLMPGP
                     QRLPRDLVEEGHTIPVARVQAMHEGKRRARARRG"
     gene            21636..23261
                     /locus_tag="F5972_RS20505"
                     /old_locus_tag="F5972_20505"
     CDS             21636..23261
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1005: Drug
                     resistance transporter, EmrB/QacA"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.5"
                     /locus_tag="F5972_RS20505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20505"
                     /product="MFS transporter"
                     /protein_id="WP_150935209.1"
                     /transl_table=11
                     /translation="MTSPTSGPTRQSWVPLIVLATGVSMVVIDATIVNVAVPAIIADLG
                     LGATDVEWVNSIYSLMFAALLIPFGQAGDRYGRRRLFALGVAVFLVASVLAAMSGSGPV
                     LIGVRAVQGVGAAMAVPMTLAIINRVYVGRQRVIAFAVWGSIIGGMAAAGPLAGGWLVT
                     EYGWRAAFWVNLPIGALLLLGSLRVPESRDGHATGGDLAGLVLAVLGTTGVVFALIEGQ
                     KYGWFEPRRTADLFGLRFESVSPVPFAFGVGVLALVALIVRERRRERAGLPVLVDLTLF
                     ELPSFRYGSMTAVIVALGEFGMILVLPLFLQSALGYTAFRAGLVIAALALGTFLAGGLV
                     PPLSKTLSPRSIVRIGLALEAAGAAGIGLSLAPDMGAWRPVPWLLLYGAGIGFATAQLT
                     GVLMADVPARLSGGASALQSTVRQLGAALGVAILGGVLVSGLGSAVERGLSDRPQQVRT
                     GVARAVEESAGAAIPALRDPAIHAAAVVAAAEATRRVTFITALALLAGVGITLLLPRTP
                     VVRDESPEQVAAGGPDTGGREPDM"
     gene            23278..23919
                     /locus_tag="F5972_RS20510"
                     /old_locus_tag="F5972_20510"
     CDS             23278..23919
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.5"
                     /locus_tag="F5972_RS20510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20510"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150935210.1"
                     /transl_table=11
                     /translation="MPRISAATVADHRANQHAALLDAAREILAAEGVQALTPAAVGARI
                     GLARSSVYRYFASTADILAQLVEDAFPRWSARLRAAVAPAGGPLPDRIRAYGRAALDFV
                     GSPDYALIPALQTIGLPPECRARVEELHGELTAPLADALREAGMDHPALRADLAWGVVR
                     AGARHLAPDIAGRETAPPEDPAGDPAEDPGAESPERIVELTLDMLTRALC"
     gene            complement(23954..24784)
                     /locus_tag="F5972_RS20515"
                     /old_locus_tag="F5972_20515"
     CDS             complement(23954..24784)
                     /EC_number="2.1.1.-"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020544541.1"
                     /locus_tag="F5972_RS20515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_20515"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_150935211.1"
                     /transl_table=11
                     /translation="MDDSRRAPEGVDPTIPNIARMYDYYLGGKDNFAADREAAEKMLAI
                     GRQMGNDGREVARENRGFLRRAVRLLAESGITQFVDIGAGLPTQENVHQVARRHAPGAR
                     VVYVDNDPVVLTHARALLADNPETIVVAGDLRDPDAVFDDPGVRAHIDFTRPFAVLLVS
                     VLHFVTDDEDADRITARIRERMVVSGCHLVLSHIRTNDEVAEEAVVESKKVYAATSSGG
                     LVGRPFKRIESFFDGLEILEPGLVPVQAWRPDVPWDVPVDMDRTGIFGAVGRMP"
     misc_feature    complement(24804..24815)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.19"
                     /tool="antismash"
ORIGIN
        1 gtgctgtcgg tcatcggccg tcccgaggtg ctgttcctgg acgagcccac gaccgggatg
       61 gacccggagg cgcgccgtac gacctggggc ctgatccgcg acctggtgac ggagggcacg
      121 accatcctgc tcaccacgca ctacctggag gaggccgagc acctcgcgag ccggctcgcc
      181 gtcatgcacg agggcgagat ccgggtcgag gggacgctgg aagaggtcgt aggcggacac
      241 ggcgaccgcg tctccttccg gctgccgccg gagctccccc tggacaccct tccgctgatc
      301 ggcggccacg cccccggcgt cagcctggcg ggcggaacgc ccgtggtcac ctacatcatc
      361 gccggtggcg accaggccac gcgggcccat gcggcgctgg tgccgctgtt cgcctgggcc
      421 gcggagcgcg gcgtcacgct cgaacggctc gccgtccgga ccgcctcgct cgaggacgtc
      481 ttccactccg tggtgaagga gagccgatga acgacgtggc acaggcggtg cggctggccc
      541 gcgtcgacct caccctcgtc ttccgcaacc gtacggcctt cgtgaacgcc gtcctgctgc
      601 cgctgctgat cgcaggggca ctggcgtcca acggcgtcgg cggggggacc ggcggcatcc
      661 cggcgacgca gtacgtgatg accgggatga tggccttcat cctgatcttc gcgacgttca
      721 tgaacctcgc cggcttctac acctcccgtc gcgaggagat ggtgctgaag cgcctgctcg
      781 gcgggccggc caccaggacg gccatcctcg gtggcagcgc cctcggcgcg accgccgtgt
      841 atctcggcca ggtgctgatc ctctgcgcgc tcatgtccgc cgtgatgggc accggggccc
      901 cggcggacgt cccgctgttg ctgctcgccg cgcttctcgg cgccgccttc ttctccctgc
      961 tcgccatggc cgtctccggc ctgtcctcca cgggggagat ggcgcagatc gcgacgctgc
     1021 cggtcgtgct gctcctggtc ggcggctcgc cggtgatgct gccgccggag atgctgcccc
     1081 aggcgctgcg tacggtgatc gagttcctgc cgatgacacc catcgtggag atcatgcgga
     1141 ccgcctacct cgggctggac tacatcggcg ccggtcacga gccgctcggc gccctggagc
     1201 gctggagcgc cgcactgccc tccctgggcc ttctcgccgt gtggatcgcg gtcgccgccc
     1261 tgatggccag ggcgttcttc cgctgggatc cgcgccgggg ctgatagata aggttgggtc
     1321 atgaacgccg ggatcaagcg ggcgcgtcac atcaccttct ggaccttggc cctcgaattg
     1381 gtgttcgcgt ggctcggccc ggtgatccag atcgtggtgg agatcaggac ggagggcggg
     1441 gtcggctgga gccgtctcgt cctcgtggcc gtcggtctcc cggtcttcag ctggctgttc
     1501 ctccgcgtcg tccgcgccgc cgtcgacggc cggcccgccg tacgcgaggt cgtcgtctcc
     1561 ggcgcgctcg ccctgacgat gatggtcctc ggggcggtcc tcgtggcgga tgtgcccggg
     1621 gtcgcttccg cgatgttgcc cttctcctgg agcacgctga ccacgacgtg gaccgcggtg
     1681 gcggtgctcg gggtgagcgc gcggaccgcc gtcgcgctga cggcgggcgc cgcgggtgtc
     1741 tacgtcgcgc tcgacttcct gttgcttccc ggcgtcggcg atcagcgcac cgacctcttc
     1801 ttctatctgc cgatgctggc gctgctcccc tacagcaacc ggctctggct gtggatctac
     1861 cgcatgatca tccaggtcga cgagggcagg aaggcgcagg ccgagctcgc cgtgaccgag
     1921 gaacgcctcc ggttcgcccg ggacctgcac gatctggtcg gccacagcct ctccgccatc
     1981 gcggtcaaga gcgagctcgc ggtcaagctc gcccgcgccg cccccgacca ggcgaccgag
     2041 gagatgacgg cggtgcgcgg gctggccaag gacgccttga aggagatccg ggaggccgtg
     2101 cggggctacc gcgccatcga tctttccgcc gagctgggca gcgtgcgggc cgtgctggag
     2161 gcggcgaaca tccggtgcac tctcgacctg ccggagcgga caccgccggg cgaggcggcc
     2221 acgctgctcg cgtgggtggt cagggagggc gccaccaaca cgctgcggca cagcgccgcg
     2281 acccggtccc gcgtcacgct gaggctgacc ggcgggacgg cggtgctgga gatggtgaac
     2341 gacggggtcg gcgaacagag cgccgccgac ggcggcaccg gtctcatcgg cctgagcgag
     2401 cggctcgccg cggccggcgg cagcctgacc gcccggccga ccggttcggg cgagttcgtc
     2461 cttcgggccg tcgtaccggc gaccgaccgc gcgcacgtcc tcaccgaggc ggtggcccga
     2521 tgagcgaccc gatgatccgt atcctcctcg ccgacgacga acatctgatc cgcggcgcga
     2581 tcgccaccct gctcgggctg gagcccgacc tggaggtcgt cgcccaggtg agccggggcg
     2641 acgaggtggc cccggccgta cgggagcacc ggcccgacgt cgtggtgctg gacatcgaga
     2701 tgcccgggat ggacggtctc accgccgccg aggggctccc gggccaagcg atgatcatct
     2761 tgagcagctt cgggcggccg ggatatctgc ggcgggcgct ggccgccggg gtgcgcggct
     2821 tcatccccaa ggacgcctcg gccgacgaac tggccacggc catccgcaag gtgcacgccg
     2881 gagggcgcta cctcgacccg gagatggcgg catcggcgat gatggcgggc gacaacccgc
     2941 tgaccgaccg cgagcgcggc gcgctggcgc tggcggccga gggcgcgtcg gtgcggcaga
     3001 tcgccacggc gctgcacctg accgagggca cggtgcgcaa ctacctgtcc agcgccatcg
     3061 ccaagctcgg cgcgaccaac cggatcaccg cgatccgcgc cgcccaggag aaaggctggc
     3121 tctgacgtcc tttcccgcct gggcggccgc ggcacccgcc cgctggtctt ccctgactcc
     3181 gtacgccgac gaccggaaca ggaacgaggc ccacgagcgg tagggccgcc aggcgtcggc
     3241 gaccttccgg tacgcgctcg ccggggcgtc cggcggcagt tcgtacgcct cgcggaggat
     3301 cgcgaacagg cgcggttcgt cgcccgggaa cgcgtcgggc gcgcccgcgc ccctgatcag
     3361 gatcagaccc gcggagaacg gccccacgcc gggcagggcg cgaagctcgg ccagcgcctc
     3421 aggcgggtcg agcgcgcgca ggtgctcggt ggtcagcacg ccgtcgagcg ccgcgcgggc
     3481 caggccgcgc agccactcct ccttctgctc gggcaggccg agcccgtcgg cgttcagcag
     3541 cgacacgggc ggcgggaagg cggcgtacgc ccggccgtcc agatcgaccg tggcgccgta
     3601 ccgctccgcg atgcgctgtt tgagccggga ggcgacgagc atcgacgagc gctgcacgat
     3661 caccgcccag caggcggcct cccacgggct ccagaagcac agcggccgca ggccgggact
     3721 gcggcgctgc aactcaccga gcaccgggtc ggactcgccg atctcggcga agcccgagcc
     3781 gtccacgtcg agggacagga tgcgggccac ctcaccccgg acatccggcc ccgcggccct
     3841 ggtcgtccgt acggcgaccc cgcccggcgc ggcggtgacc gtcacgccga tcggcagcca
     3901 gtcggcctcg gcgcagtagg cgaagcgcag cgtccggccg tcggagggca gcccgctggt
     3961 ggccggccag tcctcgacga agcggagcgt cgcgccgaag tcgaacgggc cggtggcggt
     4021 gagcgtgaat tcatgcccgg tcatgcggga catcgtacgg acgcttaccg acagttccgc
     4081 acgccgtacg ccgccgtctc ggccatgtgc cgggccgggg gtgccggccc ggcacaggtc
     4141 tgtcccgtga cagggtcagg ggctggtgca ggtggcggtg ggggtggccg cggcgccgtt
     4201 ggcggtgaag ccgaacgtcg tggacgcgcc cgccgcgacc gagccgttgt aggactcgtt
     4261 gcggacggtc accgacgagc cggaaccgct ggacacgccg ttccacaggc tgctgatgga
     4321 ctggccgccg ggccaggccc acttcacggt ccagccgttg accgccgagc tgcccgcccg
     4381 caccgtcacc tcggactgga acccgccgcc ccagctgttg atcgtcttga tcgtcgctga
     4441 gcacgccccc ggaaccggag acgacggcga ggacgacggg gaggacaagg gcgactgtga
     4501 cggcgactgc gaaggcgact gcgaaggcga cgaggtgccg ctgttgagcg cgctcagggc
     4561 cgcctggtag gcgggcttgg gctgatagct ggagtcccac atcatgggag cgccgtagcc
     4621 ggggaacgtc ccgggaatcc aggtgtggcc gtcgtccacg ccccactgcg acacgcccac
     4681 gcagcgggga accgccaggc aggcgttcac gaccctgccg tagtcggtgc cctgctgctg
     4741 cagctcggaa ctgtccgccg gcatctggat gcggtcgtcg agctcggtga tggcgacgtc
     4801 caggcccagg gcggcgaacc gctccatgtt cgcctgcagg gacgacggca cctggccgac
     4861 gatgaagtgg ctctccaacc cgatgccgtg caaggggacg ccctgggcca gcagcgactg
     4921 cgcgagcgag tagagcccgt tgctcttggc gttgatgccc tcgatgttgt agtcgttgat
     4981 gtacagcttg gcgttcgggt cggcggcgtg cgcggcccgc agcgcggcgg cgatgtagcc
     5041 ggagcccatc gccttgtaga acacgtcctg gcgcagcgtg ccgtcctcgt tgtacggctc
     5101 gttgacgacg tcccaggcgt agacctttcc cctgtagtgg gtggcctcgg tggtgatgtg
     5161 gttctccatc acaccctgga cctggttgag cggcacgccg ccgacccacg cgggcagctg
     5221 ggcgtgccac accaggttgt gcccgcgcac ccgcatgccg tgcgactggg cgaaggagac
     5281 gatctggtca cccgacccga agttgaacga gcccttggac ggctcggtgg cgtcccactt
     5341 catctcgttg ccgggggtca ccatgtcgaa ctgggccgcg gcgaggttga cctcggcgct
     5401 gataccgagg tctccccgtg tcagcgcggt gccgaagtac ctccccctgg cctccgccgc
     5461 ggccttcaac gtcgaggccg cctgagcggg gatcgcgagg ttgagcgcga cggcggtggc
     5521 ggcggcgatg gcggccaggg ccgtggccgg tccccgcgcg cgggtccgat gccgttccgt
     5581 cccggtattg ggcggtttca tgtcagccct ccagagagat ccgatcccga actgcgaacg
     5641 tgcgcacgcg ccggtccagc acagagcgtg gggttgtgag cgttaacagc ctcgggtctc
     5701 tccgctcctg ggccgatggt ggtgcagcag cggagccaat acgacgcgaa gcggcgcgtc
     5761 aaggacgcgg ccgggccgct ccccggatag gtacgccgcg aacgagccgt ttcaccacct
     5821 catccggcat cgcaccccat gccgcgggcg gagcacctct tgctgaaaca ttcactcctg
     5881 ctgacgctcc cggtcagatc gggtgcgctc acgctccgga ggcgtgaggg gagccgcgcc
     5941 atgcgtcccg gtccaggtca gaggtagccc caggccgccg cgatctcccg cagcggctcg
     6001 gccacctctt cgggaggggg cagcggacgg ccgcgctgca cccgcccgct gcgaatcttg
     6061 tcgcgccagt cgccgatgcc cttcacgaac tcgccgtggt ccttgtcgcc gtagcggatc
     6121 atctcgggct cgtactcgac accgagccag gcgcagaccc ggcgcaactc gccttccgtg
     6181 tcgtcgacca ggctctcgta ccggacgacc agcccctcgt gcctgcgcct cgactcctcc
     6241 agatagcgca tgtactgcag cgtgtgccgt acggcctcct cgacgggccg cgcctgcgga
     6301 tcggcttcgt gccaggaccg gacgatcgag gcgggatggc gcagcaggta gacgaaccgg
     6361 gcgtccggcc agcacgtcgt gatgcggcgg tgggcgaaca cgttgctggg tgtcttgtcg
     6421 acgacgatct ccttgccgct tctgaccagc tcccggtgca gcagacggtc ccacaggatg
     6481 tgctcgatgt cgctcgtact gtgcccggcc gcctccatgg cctgccgtac gggctcggtg
     6541 gtgagggtca cggcgatccg ccggacgtgc agttcgtgtg gcgcgtggat tctggaatgg
     6601 ctgttcagca gcacccggaa gagcgtggag ccggacctga ccggggagag cacgaacacc
     6661 ggcgcgcgga ggagacggtc gatctccggg tcggcgggtg gtctgggctc gtcccgcggc
     6721 ggctggacct gtgcgggacg cgggcgggcc cgggtgatga cgtaaccggt catcccttcg
     6781 acggcggcgt tgaccttgct cttccatggc atggccacga ccgtaaggag gcggggtggc
     6841 ctgctggtta acggaggctg ggggtttcca aagccgcgcc gccctccctg gcacggctct
     6901 ccgggcacgg gcagggccgg gtgggggccg tcgcgtgacc gccctccgtg gctggctcgg
     6961 cggccggccc ggcggagggc ccgctaggac ggcgagatcg ccaggaccgc ctcgtcgggc
     7021 cgcacgctcg tcagccggag gtggatgtcg ccgatgcggg cgggccggtc catggtcagc
     7081 gtcagcgctc ccctggtccg gcagcggccg ttgacgcagt cctggctgac cccgacgttc
     7141 atgccctcga cccggtagcc gccggaggag ccctcgaagc gcaggcgcac cacgccctgg
     7201 tctagggcgg ccaccgtgag cgcgtccagg ccggtggcgg cgtcgagccg cagccggtct
     7261 ccctggcgga cctccacctc gcagtcggcg ttccggcacg cctccggatc ggcggcggcc
     7321 ggaagggccg ccggggcggg ggtggccgac ggcaccggga ccgtggtgga catggtggtg
     7381 gacacggcgg cgggcgtggc ctcgggccgt gaacgcgtcc ccggctccga tgctccgcac
     7441 gccgtcgaca gcacgatcgc cggcacggcg acgaggccga tcctcccggc gaggacgaac
     7501 gcccccgatg caccccgcat gacacccgct ccctgtcgcg ccccgaatgc gccggcggcc
     7561 gcgcctcacg actgtctccg caggtcacac cggcatcgaa gactctcccc cggcaccggt
     7621 aaacgcaacc ggccgcgttc gccgtctact gccgtacggc cgtcctgcgg gcgttcccgg
     7681 tgggagccgg cacacggccg aacacgggcc cggtgcgctc aggtccgggc gccaggatcg
     7741 tgcccaggac ttcggtgatc tggtgggcgg tcctgcgcac ggccgggccc agccgcggca
     7801 gcgccgcggc gcccgccggg gccgcgacgg agacggccat gcacacccgt ccgtccggcc
     7861 cgaagacggg cgcggcggcg cagcagatcc cctcggcgaa ctcctcccgc gcgtagctca
     7921 cgccctcgac ccgtacggcc gcgagttcgc gttccagcgc ggccgggccg gtcaccgtac
     7981 ggcccgtcat ccgccggggt gcgggaccgg cgtagaaggc cttccgcagt gcggcgtcat
     8041 gcgcgagcaa cgccttgccc gcggccgtgc agtggagcgg ggcgcggtcg aggccgtccg
     8101 agggtgacgt gacgcggttg tgcccgtaca gccgttcgac gtacgcgacc tcgccgcggt
     8161 cgggcacggc gagattgacc gtctggcggg tggcctcgta cagctggagc aggtatggca
     8221 ggaccgcccg gcggcagtcc ggcacccggc ggccctgcac gggccagcca cgcggcgtca
     8281 gcagttcggc gaagcggccg tcgaccgtgt agtcgccgcc cctgcgggtg acgaggccgc
     8341 gtccctgcag gacgccgagc aggcgatgcg tggtcgtctt cgagaacccg gtcgaacggt
     8401 gcacctgggt gaggttcatc ggtctcatgc cgacggccag gcagaagaga atcgcgatcc
     8461 cgcgctccag gctgcccaga gccgacgccg tctccgccct gccggaccgt tccatcagca
     8521 cgatcacaga cctccgccgt cgcattcaga agagcagttc ttgatcggcc agcggccacc
     8581 ctagccggag cgccgcgcac gtgcggcggt ttccggcgag ggcggacggc ggccgtggag
     8641 ggcggcggcg ttcagccgac ctccacgctt tccaggacgc cgagagcgtc gggcaccagc
     8701 acggccgcgg agtgataggt ggtcacgagg taggagatga ccgccttgtc gtcgatgccg
     8761 gtgaagcgca ccgacagccc gggctcgtac tcgtccggca gcccggtgcg gcgcagcccg
     8821 acgaccccct gtttctcggt tccggtgcgc atcaccagga tcgaggtgag cccgcggtcg
     8881 gtgacgggga tcttgtcgca gggcaggatc ggaacccccc gccacgccat gaccttcgca
     8941 ccgccggcct cggtgacgtc cggatacagg ctccgggcgg tgcactggcg gccgaaggcg
     9001 gcgatggcac ggggatgggc caggaagtag tgcgagctgc gccggcggga cagcagttcg
     9061 tcgaggtcgt cgggggtggg cgggcccgac cgggtgtgga tgcgctgctt gagatcggcg
     9121 ttgtgcaaca acccgaaatc gcggttgttg accagctcgt gctcctgccg ctcccgcaac
     9181 gcctcgatcg tcagccgcaa ctgctgctcg gtctggttca tcggctcgtt gtacagatcc
     9241 gccacccgcg aatgcacccg cagaatcgtc tgcgccacac tcagctcata ctcacgcggc
     9301 cccagctcgt agtccacgaa cgtccccggc agcgtcgcct cacccacatg ccccgccgcc
     9361 agcgcgatct ccgcctcccc gtaccggttc accgggcggc cggccgcggg acggttcagc
     9421 tgctcccgca ggctgccgga gcgctcggtc agctcttcga ccaccggccg ttcgagcacg
     9481 agcacgatgc accgggtgag cgccttcgcg ggggccgccg ccgggccggt gagatcgccg
     9541 aggtgatccc cgtcggcgac gacccggagc agcgtctcac cgccgtactc gccgacgccg
     9601 acacaggcga tcttgccgtg ggcgaccagg accacctgac cggcgggcac cggttcgtcc
     9661 ggttccagtt cgtgctgcac gaaccggtcc gccagggcgg ccagcacgtc cgcgtcggcg
     9721 tacccgtgca aagacggcag ttcgcacagc tcggccggga tcacccgcac ctcggccccg
     9781 gtcgagacga acgtcacccg cccgtctccc ggggtgtagg tcagccgccg gttgacccgg
     9841 tagaccccgc cctggacgtc gatccacggg agcacccgca gcaggtggcg gggggtgatc
     9901 tcgcgcatct gcggcggggt cttggtggtg gtcgccaggg tgcgcgcggc cctggtgctc
     9961 agggccagcc gcgacgcgcc atcgggcccg agcggcgcgc tcacgacgca cccgccgtga
    10021 ggtggagcac gggcgcgggc gcgacgccgt ccccggcggg cccgccgtac gcggacgcga
    10081 gggagccgat cctcgcggtg gcggtgccga ggccggtcgg gccctgggtc caccgggcca
    10141 ccggacccgc gcgcagttcc tcgtcgagat agcgccggga ccgttggtgc cagcgcagga
    10201 tggcggccat ccagttgcgc agatcggtca cgtacgccgc gaccgactcc cgtacggcct
    10261 cgcccgcgtc gatccggtcg agcagcgcgg gcaggtcgac ggtggtgatg tgctcgaact
    10321 gcctcatccg gctcgtcatg agcccgtcca ccaccgtcac gccctcctgc ggcgggcagt
    10381 ccaggaatgt ggacatcacc aggaccgcgt tgtgcagctc gccctcgtac cggatctcct
    10441 tgcggtagga gaacaggtcg ttgagcaggc acgcgtagtc ctgcgcggcg tcggtcatgc
    10501 cgaggaactc ccgggtcagg atgatctcct ccgggatgac ccggcccggc gcgagcctgg
    10561 cgagactcat cgtcatcccc gagccgaagg tcgcgcgccg catctccagg tagtcgacgg
    10621 ggtcgggcac ccggtgctgg gcctcgttgg ccagctccca cacccagctg tcgatcatct
    10681 cctccaccga cgtgcggaag atctcgcggg agccgggcgg cagtggcccg gcggtgcgcg
    10741 gccacaggtc ggcgagcccg cgttccagcc cggtcagcgg ggtcagccgc gggacgaggt
    10801 ccagcggcat gagctccttg agccgccggt tcaggagctt cgcgccgacc aggtcacgcg
    10861 ccgcgccgaa gacccgggga tagtagtcgt cgccgtacgt cccccaggcc agccagttgg
    10921 tggccaggac gagctcgtcg gcggtggcgt ccggggtgat gccggacgcg cacagggcca
    10981 ggtcgaatcc ggcgagccgc cgttcgtccc acacggcggt cgccgggatg cccggaaccc
    11041 cgtcgaagaa gcccatcgcc gcacaccact ccaggtcggc cgcgcgcgcc gcgtccaggt
    11101 gcgggttgtc gcgcacctcg aacggcatgt acggctcggg cagccgcacg tcggcctccg
    11161 cgaagggccg gtgggtgtgg ttgcgcaggc cgcccgcacc cgtgacatgg gcgcgggaga
    11221 cgttcatccc gaagatcccc gcctgtccgc cgttcttggt gtagcgactg gaggccgagt
    11281 gccaggcgtg gccgcccgcc tgccagtcct gcagcccctt ggcgtaccgg aggacgagcc
    11341 cctgctcggg cggcgagacc gcctcgtcgg cgaagagcgc cggcagttcg gtcagggcgg
    11401 tgtgctcgaa ctggtgcagc cgcgacgtga gcaggtcgtt ggtgatctcc acggcccgtt
    11461 cggtgtcgca gccgaagaag cgctcgcaga ccagcacgca gttggacagc tcaccctcct
    11521 cccgcacctc ccgctcgtag gagaacaggt cgttgcgcag gtgcacggag tcggcgaacg
    11581 actgcgtcag cacccggatc ggccgggatc cggccagccg ggccggaagc tccgcgcccg
    11641 ccgcgtgctc gaccagcgcc gccgaccacg gggcgccgcc gaccttccgg cgttcctcga
    11701 tgtactcgat ggggttggag acggcgtccc gctcgatgtg gaacaactcc cacatcgact
    11761 cctggagcag atcccgggtg acccggacga accgccgccg ccacgccgcc gacatggcgg
    11821 gcacggtccg gggccacagg tcggccagcc cccgctccac cgggttggcc gcctcgggcg
    11881 ggtcgtccga catgaacgcg tcgagccggt cgaggtactc ctgggcaccg ccgagatccc
    11941 tgccgcgctt gaaggtctcc aggaagtggt cgtcgaagaa gaagacccag acgtaccagt
    12001 cagtgaccag atccagctcg ggggcggagc agtcggggtg ggtgtaggcg cacatcaggc
    12061 cgtagtccat cgcgtcgagc gactcctcgg tccagatgtc cgggtcgtcc agcatcccca
    12121 tctgccccgc ccagccgcgg gtgtgcgtgc gggcggtctc gacgtgcggg ttcagcctcg
    12181 gcggatacgg gaggtagaag tccggcagcc ggtaggagga catcacagga cctcgacgct
    12241 ctccaggatg ccgagggcgt cggggaccag cacggccgcc gagtagtagg tggtgacgag
    12301 gtaggagatg atcgccttgt cgtcgatgcc catgaagcgc accgacagcc cgggctcgta
    12361 ctcgtccacg aggcccgtgc ggcgcagccc gacgacgccc tggtccttct cccccaggcg
    12421 catgaccatg atcgagctga cgccctggcc gttgacgggg atcttgttgc acggcagcag
    12481 cgggaccccg cgccaggcgg gcgccttctg gccgttgaac tccacggtct gcggatagat
    12541 gccccggctg ttgcactgcc gggcgaaggc cgcgatcgcc ttgggatggg cgaacatgac
    12601 ggtcgggttc ttccagaccg tggtcagcag ttcgtcgagg tcgtcggggg tgggcgggcc
    12661 cgaccgggtg tggatgcgct gcttgagatc ggcgttgtgc aacaacccga aatcgcggtt
    12721 gttgaccagc tcgtgctcct gccgctcccg caacgcctcg atcgtcagcc gcaactgctg
    12781 ctcggtctgg ttcatcggct cgttgtacag atccgccacc cgcgaatgca cccgcagaat
    12841 cgtctgcgcc acactcagct catactcacg cggccccagc tcgtagtcca cgaacgtccc
    12901 cggcagcgtc gcctcaccca catgccccgc cgccagcgcg atctccgcct ccccgtaccg
    12961 gttcaccggg ccgtccgggt cctcccggta cgccgacacg tgctcgcgca ggctctccga
    13021 caacgccagc aggcgctcga aggcgtccct ggtgagggcg agcaccgtgc agggcgtcac
    13081 cgtccgcacc gtccactccc accgcgcgtc gggatgcacc agcatctgct cgccgacgta
    13141 ctccccgtcg gccagcactc ccagcagagt ctcgttgccg tacgccccct caccgatctt
    13201 gtcgaccttg ccgtgcgcca gcagcacgac ctcctccatc ggagcccccg ccgccgcgat
    13261 gacctgcccc gcctcgtact cccgctgcgt gaacaggtcg cccagcgacg ccagcacgtc
    13321 ggcgtcgccg aacccccgca gtgccggcag ctcgcacagc tcggcggaga tgacccgcac
    13381 ctccgcgccg gtcgagacga acgtcacgcg cccgtcggcc acctggtagg tcagccggcg
    13441 gttgacccgg tagacgccgc ctatggcctc gatccagggc agcacgcgca gcaggtgccg
    13501 ggaggtgatc tcctgcatct gcggcggggt cttggtcgtc gtggccaggt tgcgtgcggc
    13561 cctggtgctc aggctgagcc tgctgtcgtt cggcgcgctg gtctgcgggg tcgtttcggt
    13621 cacagcacat cacccatctt ctgatcggcc ggcggccggt tgtccgctaa caggtcgtgc
    13681 tcgtcgccga gcggtggagg ggaaggcgtc ggaagggcgc ccccggtggg ccgcgagccg
    13741 ccggaccggc cccggtgcgg gatgtgcggg aagccgctga cgacgcgggt gtgccgttcg
    13801 cgcgcctcac cggacgcgac gcgtgagccg ctcggtgagc accgcgagcg cctcggccgc
    13861 ctccggcgtg atcgggcagt cgcgcagcgc cgccagcgcc tggccggtcc gctgggtgat
    13921 cagctcctcg acccggtcga gcgcgccggt gtccacgatg atccgccgca gctccgccgc
    13981 gcgcgcctcg tccagggcgg gatcgccgtg ccaggtgcgc agcaggtccc gttccggccc
    14041 gcgggcccgc gcggaggcgt acgccatgag cacggtccgt tttccctcgc gcaggtcgtc
    14101 gaggacgggc ttgccggtga ccgaggggtc gccgaagacg ccgaggacgt cgtcgcgcag
    14161 ctggaacgcc tcccccagcg gcaggccgaa ccgggagtag gcgtccagca ggctcggcgg
    14221 ggccccggcg agcgccgcgc cgatctgcag cggccgctcc acggtgtaac gcgccgtctt
    14281 gtaccggatc accgtgagcg cctgctcgac cccgtcgtcg ccccgcgcgt gcgccagcag
    14341 gtcgaggtac tgaccggtga cgacctcggt gcgcatgcgg ttgaagaggt cgcgggccgc
    14401 gcgggcccgc acgtcggcgg gaccggcgtc cgcgagcagt tcctcggccc aggcctgggc
    14461 gagcacgccc aggaggatcg ccgcggactg gccgaactgc tcggccgccc cgaaccgccc
    14521 cggccgcgcg agcccccggt ggatggtcgg acgcccccgg cgcagctcgc tgccgtccat
    14581 gaggtcgtcg tggatgagga gaccggcgtg gtagagctcc agcgccgcgc cggtggcaac
    14641 aaccgccgcc tcgcgaagct cttcaccgcc ggcgccccgc cagccccagt aacacagcag
    14701 aggccggacc cgtttgccgc ccttgaccac gaactcacgc agcaggcggt atccctcggc
    14761 cacgtcatgg tcgccgaccg gagggcgccg cgcgtcgagg aagtcggaca gcagttcgtc
    14821 gacacgtctc cggacccggc cggtgatgcc ggtgatggac gtgtccacga tctccgccgt
    14881 catggtcggc ctcctcgtcg gcgcgccggt ctcccctgcg gaaagttact taatgagcac
    14941 gcaaagtaga accatgcgtt ccgatagtcg gaacttctca ccggcccgcg ccgtgatccg
    15001 tcacatcacg cgaaaaaccg gctccgcgaa gcggcgccgg tcctcgcggc cgatccaccg
    15061 gccgggttgc gggaggggtc agggcaggcg gtggccgtgg cggtcgcggg ccttcagccg
    15121 tacggtgggc atctcgggcg cgggcagcgg ctcctggccg cccgggacga cgccgaagcg
    15181 ggcgccgcgc gcccagtcgt cacgggccgc cgcgatctcc tcgtgcgtac ggccgacgaa
    15241 gttccaccac atgaccaggg gttcctcgaa cggcgtcccg ccgaggacga acagccgcgc
    15301 gggcccggtg gtctccagcg gcacgtccgc acggccctgc ccgaggtaga gcagcgatcc
    15361 gggcgacagc gccgccccgg ccacctccgc cgtgccggac atggccagca ccgccgtctc
    15421 gaaggccggg tcgaccggca ggcggtgccg gccggggccg ccgaacagca cctcggcccc
    15481 gagcagcggg gtgtgcgccc gcgcgggcga ccgggccgct cccacctctc ccaccacgac
    15541 ggtgaccgtg acgttcccgt cgcgcagcac gggcagcgcg gcatggtgct cgaaccgcgc
    15601 ctcgccgtgc cgggcgtcct ccggcagcgc gacccacagt tgcagcccgt gcatctccgg
    15661 cgggtggtcc ggcggcgact gttcggagtg ggcgatcccg tgggccgcgg tcatcaggtt
    15721 gagctgcccc ggcacgatcg gctgggtgtt gccgaggctg tcgcggtgca ggatctcgcc
    15781 ctcggcgagc caggtgaccg tctgcagtcc ggtgtgcgga tgcggcggca cccgcatgcc
    15841 cggccggccg cgcacgtcgt ccgggccgaa gtggtccacg aagcaccacg ccccgaccat
    15901 ccggcgcggg cgctgcggga gcagccggcg caccgtcgtg taccggccga gcggcacgtc
    15961 gtggccgggc aggagcacgc tctccggcat cgcctcggcg gcgcccgtgc tgcaattgag
    16021 aaccgtaccg ccgtagagcg cgggctcccc ctccccccgg ctcagcgggc cggcggtcac
    16081 ccggccgcct cgtcgccgtc cagcgagaac cgggcccgcc ggtcggccgg caccagatcg
    16141 acgtactccc ggtgccgcgc gatgtaccgc cgtacgaacg ggcagtacgg caggaccgac
    16201 agcccggcgt cgcgcgcggc gtcgagcgcg gcgcggacca gcgtcgagcc gaggccgcgg
    16261 ccctcgaacg cggagtcgat ctcggtgtgg gtgaaggaga tcgtctgccc gtcgagcccg
    16321 taggcggcga agccggcgag gacgccgtca acggtgatct cgaagcggcg cgcctcgggg
    16381 ttgtcggcga ccttcgggtc tgtctgctcc atcaggtgtc tgtccttccc agatagtcac
    16441 gcggcgatgg tcgcgtgcat ctcccacacg aggatctcgg cgggctcggt cgcggtgacc
    16501 ttctgcccgc cggtggcggt gaaccgtacg gcgtcgccgg tctccagcat gcccgcaccc
    16561 tccagggcga cggcgccccg gggcacgaac aggtgcagga acggcgcctc gggcagctcc
    16621 accgactggc cggtctccag gcgggcggcg tacagcgcgg cgtaccggtt cttgatccgg
    16681 atggccgcgg cgccgtcgtg cttgtccatg ccggaggcca ccggcaccag gccgccggcc
    16741 agcaggtcgc cctcgatctc cagctgctcg tacccggggg tgatgccagg ctcgtcgggg
    16801 accacccaca tctggacgaa gtggacgggc tcgtcatggg cgccgccgcc ggtcagccgc
    16861 caggagtcgt tcttctccga gtgcaggatg ccggtgcccg cgctcatgcg ctgggcgagc
    16921 cccgggtaga tgaccccgga gtggccctcg gagtcctggt ggaccaggga gccccggagc
    16981 acccaggtga cgatctccat gtcccggtgc gggtgcgtct cgaacccggt gcccgggtgg
    17041 acggtgtcgt cgttgttcac cagcagcagg ccgtggtggg tgttgccggg gtcgtggtgg
    17101 ccgccgaacg agaacgagtg cctggaatcc agccaggaga tgcgggtgga gaagcgctcg
    17161 gccgccctgc ggacgtccac acggggggtc agcctggtcg tggtcatcgg aaccctttcc
    17221 tcgtcgcctt gtagatgatg catcatctac tggtgcccca caacatagat gacgagtcat
    17281 tgattccggc tagcctggac ggcatgaaca gcccacgctg gctcgacccg gacgaacagc
    17341 gcgcctggcg ggcctacctg cgcatgcagg gtcgtctcac ggcccggctc aaccgggagc
    17401 tgcaggccgg ttccggcctt tccctggccg actacgaggt cctcgtgcac ctcaccgacc
    17461 gcgccgacgg gcggttgcgg ccgttcgagc tggagcgcgg cctccagtgg gagcagagcc
    17521 gcctgtccca ccacctgacc cgcatgcagc gccggggcct cgtccgccgc gaggagtgcg
    17581 cggaggacgg ccggggcgcg ttcgtcgtga tcagcgagca gggccgccgc gccatcgccg
    17641 ccgccgcccc ggggcacgtg gagaccgtac gccgcctgtt cttcgacggg ctcacccgcg
    17701 aacaggtcgc cgcgctcgaa gggctgtccg ccgacgtgct cgcccgcctc gacgacgaca
    17761 acaccgacgg ccacccgggc gacgacactg acgacagcct cagctgacca gtccctcggg
    17821 gaagacgacg ccggcgacgc cggggacggt cctgacgacc atctcggcga tgcgggccgc
    17881 ccgctcgtcg cccgggccgt acaactcgac gacgccgctc cgcacggccg cgccgaaggc
    17941 cgccgtgtct gcgcagtcgc gcagcgccgc gagcacgtcg tcgcggatcc gctcgtcccc
    18001 ctggaccagc agccccatca ggtcgcgccg gctgacgatg ccgacgaggt cgtcgtcgcg
    18061 caccaccggg acgctcttca ccccggtggt gatcatcagg tcgaggaggt ccatgacgtc
    18121 ggccgcgtcg cccacggtgg cgacgcgcgg cgtcatgacc tcctcgacga gcgcgggcgg
    18181 cctgccggtg ggcagggcct cggggcgcag gaaggcccgg ggatcggtct cgaactcgcc
    18241 gcgcagcaga tccatctcgc tgacgatgcc gaccatccgt cccggccgtt cgaccaccgg
    18301 cgcggccgtg atttcctgtt cgtacagcag gcggacggcc tgcctgatcg tcgccgtgcg
    18361 gcgcaccgtc accaccggcg ccgtcatgat ctcgtggacc agcatcgtga tcacctccta
    18421 cccggccggc gcgaggacga gtgtcccgcc cggcgccggt ccggtccgcg cgccgaacct
    18481 ccggccgatc cggtcgaggg tcccgcgcag ccactcgcgg tcctcgtcgc cggcgtgccg
    18541 cagccgcatg cgtacggccc gcatcggcgc catccgcagt tcgcgcagcc gccccgacgc
    18601 ggcctccacc gtcgcgaaat acagcagccg caggtcgtcg cggtactcct catagccggt
    18661 gatgccctcg tagtcgtcga tgaagtcgcc gcagccgtag aggatcagcc ggtcgcggta
    18721 cacctccgcc gggcgggggt ggtgcgagga gtggccgtgg acgaggtcga cgccgccgtc
    18781 gacgagcgcg tgcgcgaacc cggcctggtc gtcgccgacc tcgtagcccc agttcgaccc
    18841 ccagtggacg gagacgacca cgacgtcccc cgggcgcctg gcccgccgta cgtggtggac
    18901 ggtctcggcc gcgcagccgg gggacggcgc cgggaggaag gccaccccgg gccggtcccg
    18961 gcgggccgcc cacccgcccg ggacgccgct ggacggcatc gcgaccgcga acaccagcac
    19021 gcggccgccg ccggggagcg gcacgaccgc gggccgccac gcctcgtcct cgtcgcggcc
    19081 cgccccggcc cggccgagcc ccgcctccgc caggacgtcg agcgtctcgg cgagcccgcg
    19141 tacgccgaag tcgagcacgt ggttgttggc cagcacgcac acgtccggcc gggccacggt
    19201 cagcgcggga aggttggctg ggttcatccg gtagtgcacg gccttgtccg gcgcgaagtc
    19261 ggcggacctg gtgacgctcg tctccaggtt gagcacgcgg acgtcgggag cggcctcgtc
    19321 cagcacctcc agcgcgtcgc cccagggcca ggagcaggcg gccgggcgcg ggatcgggcc
    19381 gttcgccgcc tccgccagat cgacgtacgc cccggcgtcc cggacgtgcg gctcccgcag
    19441 ggcgggatcg cccgggtgcg ggaggatctg gtcgacgccg cgcccgagca tgacgtcccc
    19501 gcacaggaac agggtgaccg gatcccccgc cgccgaccgc atgccaaccc cccgatggcc
    19561 ccctcacgac cccctgatga ccgggcgggc cccgtcctcc gcgggtcaca ccccgatcct
    19621 tccccgtgac cggccacgcc accacagcgg ggaggggtgg tcagcccacc cggcagagga
    19681 tctcgccgtg cacgacgctg aaccagccgt ccgcgctcgc gccccactcc cgccagccgt
    19741 cggagatccg ccgcaggtcg tcctgggtgg cgtggccgcc ctcgatcacc cggctcgcgt
    19801 aggaggactg gagggtgcgg tcggcccaca ggccgctcca ccacgcccgg tcctccggag
    19861 tggcgaaaca ccaggtggac gacgacgagg tgatctcggc gaagccggcc tccccggccc
    19921 aggagcgcag gcgccgcccg gcgtcgggct cgccgccgtt ggcccgggcg acccggtgat
    19981 agaggtccag ccagtcgtcc agcgcgggga ccagcggata ccagatcatg ccggcgtagt
    20041 cggagtcgcg tgccgcgacg atgccgcccg gcttcgtcac gcgccgcatc tcgcgcagcg
    20101 cgcccaccgg atcgccgacg tgctggagca cctggtgggc gtgcacgacg cagaaggagg
    20161 cgtcgggaga gccgagcgcg tgcacgtcgc cggtcgtgaa gctcacgttg ccgacgccgc
    20221 gccgcgccgc ctcctcccgg gcctgctcca ccacggcggg cgcgttgtcg aggccgacca
    20281 cctcgccctc cggcacgtac gcggccaggt cggcggtgat cgtgccgggg ccgcagccga
    20341 cgtccaggac gcgcatgtgg ggcttcagcg cgccgagcag gtacgccgcg gagttggcgg
    20401 cggtgcgcca gcggtgggag cgcaggacgg actcgtgatg accgtgtgtg tagacggccg
    20461 attcgtgtgc catgccgcca ctattccact cgtctcgtta tttgagcaat tatgtctcac
    20521 attgagagac gatgccgaga ggtgcccggc cgcgttgatt tccgccgccg gtcgcgggca
    20581 tggtgatcgg atgaccagcg atgaggttcg cgacggagtc acgctgacca acctcgacca
    20641 gccgttgttc gacggcgcgg gcgcggccaa gcgcgacctg gtcgactacc tggacgccgt
    20701 acgcgaccgg atcgtcccgg tgctgcgcga ccggccgctg tccgtcgtgc gggtccggca
    20761 gggccaggcg ccgttcatgc agaagaacgt gccgtcgtac gccccggact gggtgcggac
    20821 ggtgacggtg tgggccgagt cctcccagcg gcgggtgtcg tacgcgttgt gcgacgaccg
    20881 gcggaccctg ctgtggctcg ccaaccagcg ggcggtggag tatcaccccg ccctcgtcca
    20941 cgcgggccat tgggaccggc ccacccacct cgtgctcgac atcgacccgc cgtccgccga
    21001 ggcgttcccc cgggccgtcg gcgccgcccg cctggtcgcc cgggcgctcg ccgacgccgg
    21061 gctgtcgggc gcggtgaaga ccagcggcgc gaagggcctg cacgtgttcg tgccgctgga
    21121 gggcgagacc acggaggacg tggccgccgc cacccgcgcg ctcggcgtcc gggccgaacg
    21181 cctcgatccc gccctcgcca cgacggcgtt catccgggag gaccggggag acaaggtgtt
    21241 cgtcgactcg acccggtccg gcggggcgac cgtcgtcgcg gcctacagcc cgcgcgtacg
    21301 gcccggcgtc ccggtctcct tcccggtcgc ctgggacgac ctggaccgga tcacgcccgg
    21361 cgacttcacc gtgcgcacgg cggcgcgcct gctgcgcgac ggcgatccct gggccgacct
    21421 gatgccgggg ccccagcgcc ttccccgcga cctggtcgag gagggccaca cgatcccggt
    21481 cgcccgcgtg caggccatgc acgagggcaa acgccgcgcc cgcgcccgcc gcggatagcc
    21541 gtcccggagg ttcaccgccg gtccgccacc ggtccccgcc cggcttccgg gcggggttga
    21601 caggttgccg acagggcgtt gctatagttc gcgacatgac gtcgccaaca tcgggcccga
    21661 cacgccaaag ctgggtccct ctcatcgtgc tcgccacggg cgtgtcgatg gtcgtcatcg
    21721 acgccacgat cgtgaacgtg gcggtgcccg cgatcatcgc cgacctgggc ctcggcgcca
    21781 cggacgtgga gtgggtcaac tcgatctact cgctgatgtt cgcggcactg ctcatcccgt
    21841 tcggccaggc cggcgaccgg tacggcaggc gccgcctgtt cgccctcggc gtcgcggtct
    21901 tcctggtggc gagcgtgctg gcggcgatgt cgggaagcgg gcctgtgctc atcggcgtgc
    21961 gggccgtgca gggcgtgggg gcggcgatgg ccgtcccgat gaccctcgcg atcatcaacc
    22021 gcgtgtacgt gggccgtcag cgggtgatcg ccttcgccgt gtggggctcc atcatcggcg
    22081 gcatggccgc cgccggcccg ctggcggggg gctggctggt caccgagtac ggctggcgcg
    22141 ccgcgttctg ggtcaacctg cccatcggcg cgctgctcct gctcggctcg ctgcgggtgc
    22201 ccgagtcccg ggacggccac gcgacgggcg gcgacctggc cgggctcgtc ctcgccgtgc
    22261 tcggcacgac cggcgtcgtc ttcgcgctga tcgagggcca gaaatacggc tggttcgagc
    22321 cgcggcggac cgcggacctg ttcggcctgc ggttcgagag cgtctccccc gtgccgttcg
    22381 ccttcggcgt cggcgtcctc gcgctggtcg ccctgatcgt gcgcgaacgg cggcgcgagc
    22441 gcgccggcct gcccgtgctc gtcgacctga cgctgttcga gctgccgagt ttccgctacg
    22501 gctcgatgac ggcggtgatc gtggcgctcg gcgagttcgg catgatcctc gtgctgccgc
    22561 tcttcctgca gtccgcgctc ggctacaccg ccttccgggc cggtctcgtc atcgccgcgc
    22621 tggccctcgg caccttcctc gcgggcgggc tggtcccccc gctgtcgaag accttgtccc
    22681 cgcggtccat cgtgcggatc ggcctggccc tggaggcggc cggcgcggcc ggcatcggcc
    22741 tgtccctcgc gccggacatg ggcgcctggc ggccggtgcc gtggctgctc ctctacggcg
    22801 cgggcatcgg cttcgccacg gcgcagctca ccggcgtcct catggccgac gtgccggcgc
    22861 gtctgtccgg cggcgcgtcc gcgctccaga gcacggtccg ccaactcggc gcggcgctgg
    22921 gagtcgccat cctcggcggg gtgctggtgt ccggactcgg ctcggccgtc gagcgcgggc
    22981 tctccgaccg gccccagcag gtgcgcacgg gcgtggcgcg cgcggtcgag gagagtgccg
    23041 gcgccgccat ccccgcactc cgggacccgg cgatccacgc ggcggcggtc gtggccgccg
    23101 ccgaggcgac ccgcagggtc accttcatca cggcactggc gctgctcgcc ggggtcggca
    23161 tcaccctcct gctcccccgt acgccggtcg tgcgggacga gtctccggag caggtcgctg
    23221 ccggagggcc ggatactgga ggtcgcgagc cggacatgtg acagccctgg aggggagatg
    23281 ccgagaatca gcgcggcgac cgtcgcggac caccgggcca accagcacgc cgccctgctc
    23341 gacgcggcgc gggagatcct ggccgccgag ggcgtgcagg cgctcactcc ggcggctgtc
    23401 ggcgcccgga tcggcctggc ccgctccagc gtctaccgct acttcgcctc caccgccgac
    23461 atcctcgccc agctcgtgga ggacgccttt ccccgctggt ccgcgcgcct gcgcgccgcc
    23521 gtcgcgcccg cgggcggccc gctgccggac cggatccgcg cgtacggcag ggcggcgctc
    23581 gacttcgtcg gcagccccga ctacgcgctg atcccggcgc tgcagacgat cgggctgccg
    23641 cccgagtgcc gggccagggt ggaggaactg cacggcgagc tgaccgcgcc gctcgcggac
    23701 gcgctgcgcg aggccgggat ggaccacccc gcgctgcggg ccgacctggc ctggggcgtg
    23761 gtccgcgcgg gggcccgcca tctggcgccg gacatcgccg ggcgcgagac ggcgcccccc
    23821 gaagatcccg cgggagatcc cgccgaagac cctggcgcgg agtctccgga aaggatcgtc
    23881 gaactcaccc tcgacatgct cacccgggcg ctgtgctgac ccgcggccgc tgaaccccgc
    23941 ggccgctgcc cggtcagggc atgcggccga ccgccccgaa gatgccggtc ctgtccatgt
    24001 cgaccggcac gtcccagggg acgtcaggcc gccacgcctg cacgggcacg aggccgggct
    24061 ccaggatctc caggccgtcg aagaacgact cgatccgctt gaacggcctg cccacgagcc
    24121 cgccggagga ggtggcggcg tacaccttct tgctctccac gacggcctcc tcggccacct
    24181 cgtcgttcgt ccggatgtgc gacagcacca ggtggcaccc cgacaccacc atccgctcgc
    24241 ggatccgggc cgtgatccgg tcggcgtcct cgtcgtcggt cacgaagtgc agcaccgaga
    24301 ccagcagcac cgcgaacggc cgggtgaagt cgatgtgggc gcgcaccccg gggtcgtcga
    24361 agacggcgtc cgggtcccgc aggtccccgg ccaccacgat cgtctcgggg ttgtcggcca
    24421 gcagcgctcg cgcgtgcgtg aggaccaccg ggtcgttgtc gacgtagacc acccgcgctc
    24481 cgggggcgtg ccgccgcgcg acctggtgga cgttctcctg cgtcggcagg cccgcgccga
    24541 tgtcgacgaa ctgtgtgatc cccgactcgg ccaggagccg caccgcacgc cgcaggaagc
    24601 cgcggttctc cctggcgacc tcccggccgt cgttgcccat ctgccgcccg atggcgagca
    24661 tcttctcggc ggcctcccgg tcggcggcga agttgtcctt gccgcccagg tagtagtcgt
    24721 acatccgggc gatgttcggg atggtgggat cgacgccctc cggcgcccgc ctcgagtcgt
    24781 ccaagcgtct gcccctcgcc tatggaaccg ctttcatcgc attgtaggcg aggaggcggt
    24841 cgaagatcat caccctgggg tcatcactcc gcgattggag aac
//
