LOCUS       NZ_VYTZ01000005        30168 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold5, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000005
VERSION     NZ_VYTZ01000005.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 646337)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 646337)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 600748
            Orig. end                         :: 630916
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000005.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..30168
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="azole-containing-RiPP"
                     /product="thioamitides"
                     /region_number="4"
                     /rules="((YcaO or TIGR03604) and (((thio_amide and (PF06968
                     or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N
                     or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or
                     PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or
                     thiostrepton or TIGR03602)"
                     /rules="((YcaO or TIGR03604) and TfuA)"
                     /tool="antismash"
     cand_cluster    1..30168
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((YcaO or TIGR03604) and (((thio_amide
                     and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /detection_rules="((YcaO or TIGR03604) and TfuA)"
                     /kind="chemical_hybrid"
                     /product="azole-containing-RiPP"
                     /product="thioamitides"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..30168
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:20168]"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..20168
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="((YcaO or TIGR03604) and (((thio_amide and
                     (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or
                     Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or
                     (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or
                     TIGR03603 or thiostrepton or TIGR03602)"
                     /neighbourhood="10000"
                     /product="azole-containing-RiPP"
                     /protocluster_number="1"
     gene            240..1832
                     /locus_tag="F5972_RS16990"
                     /old_locus_tag="F5972_16990"
     CDS             240..1832
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00976.1"
                     /locus_tag="F5972_RS16990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_16990"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_191910162.1"
                     /transl_table=11
                     /translation="MPKLNRPPLPVVVEHDSPMPMRDGTVLRGSVHRPADGGPFPALLV
                     RTPYGEDSFRTEPVLPALRAGFAVVLQHCRGRGTSDGEFRPWLDEGADGHDTIGWITSQ
                     PWSNGEVVMSGMSYLAGCALQAAATRPPGLKAVVAAMTPHDFHDGLKYHGGALALGSAL
                     NWGAFQAMLGLLHAAEAGEDTGAALAEVLRVLADQETAVRTLPVGDVPGIPWWHDWTSH
                     VTRDAYWEGLAETLRHDRVEVPVMHVAGWFDLFLAGTLENHRRLGGPLVVGPWSHLAPG
                     AGGTGRLFFGAAASAQAIGLEERQMAFLAGKDDGPAVRIFVMGDDVWRDEEAWPLERAV
                     DTPYYLHADGLLSPEPPSAAEPAVFVFDPRDPVPTVGGPTLLADPTNVGPQDQRDVERR
                     PDVLCYSTEVLASDVEVTGPVSVTLRAETSAASTDWTAKLVDVHPDGRAMSVIDGIVRV
                     LAPSGTFVIDLVATSQVFRAGHRIRVEISSSNFPRFDRNPGTGRPGSGEADLVVQHQKV
                     HPDSYVTLPIVPR"
     misc_feature    708..710
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(1936..2817)
                     /locus_tag="F5972_RS16995"
                     /old_locus_tag="F5972_16995"
     CDS             complement(1936..2817)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS16995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_16995"
                     /product="hypothetical protein"
                     /protein_id="WP_150934435.1"
                     /transl_table=11
                     /translation="MLTIEHEAVIRLFQERPDLAAGLLARSLDVQLPDFDYAAVESADL
                     TEVTPASRHADSVIVFRRKRPGADPEPVVAVIVEVQRGRDPGKLWSWPMYLVSLRTRLE
                     CPVMLLVICPEAAVARWCARPIELGHPGLVPTPLVAGPDEVPVITDPGQAADDIELAML
                     SVIHHAATPQGPDILNALFAALHNLDRDQGGMYADMVRAALPREIWDHLERHMKTESYE
                     YLSDWARENIAKGQTEGKTEAILTVLAARGIEVPDELNDKIRKCRDLDRLDAWIRAAAT
                     VQSADALLNNDL"
     misc_feature    complement(2800..2815)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     misc_feature    complement(2847..2862)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 19.65"
                     /tool="antismash"
     misc_feature    complement(2854..2868)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.58"
                     /tool="antismash"
     misc_feature    2860..2875
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.31"
                     /tool="antismash"
     misc_feature    complement(2862..2875)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.77"
                     /tool="antismash"
     misc_feature    complement(2865..2878)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 14.09"
                     /tool="antismash"
     misc_feature    2868..2885
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: weak, score: 16.82"
                     /tool="antismash"
     gene            complement(2913..3446)
                     /locus_tag="F5972_RS17000"
                     /old_locus_tag="F5972_17000"
     CDS             complement(2913..3446)
                     /EC_number="2.7.1.-"
                     /GO_function="GO:0003950 - NAD+-protein
                     poly-ADP-ribosyltransferase activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132967.1"
                     /locus_tag="F5972_RS17000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17000"
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="WP_150934436.1"
                     /transl_table=11
                     /translation="MDERRLVRVSKYLAKHLRHEPERIGIELDAHGWVAVDTLLTAAAA
                     HGFPISRAELEQVVADNDKRRYVIEGERIRASQGHSVAVDLDLPVAEPPPILYHGTVAR
                     NVEAIREEGLRPMERHHVHLSPDRETATRVGARRGRPVVLVVDAAAMHAAGHRFRLSAN
                     GVWLVDHVPPAYLR"
     gene            complement(3714..5810)
                     /locus_tag="F5972_RS17005"
                     /old_locus_tag="F5972_17005"
     CDS             complement(3714..5810)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020540489.1"
                     /locus_tag="F5972_RS17005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17005"
                     /product="hypothetical protein"
                     /protein_id="WP_225311561.1"
                     /transl_table=11
                     /translation="MEDLVIARRLRVPVDVEGDGTPGWGEVAARQLDAALLSVGFTCSP
                     ALLDRLARLPGEQVIDLGLRVLAAVRRLVGDHVEHNAYFVDFPRNVPDTLDFWAGLLRE
                     AMLDPVAAARLQPGTLNLLDLPRYGRYQHTYADLLAAHDELIPLARDRVTVLELGGSLR
                     DEACELYFSLAGSEVPLAAEDLTALRALAAFCAGDRPEHVPVRENRAVLNEVRLAAGQP
                     LLVDTVTDVLRVAALCSGGDVTLSIPARLRSFRRAERRILLAALDAVPAAKHGDVLRHR
                     EQWKRLGERLHPHEYPQYPRAVQVFEVARGARKAASFGGRVEAALAEGRTADAVALLEH
                     TPGALLRRLDHLLRTGGGPAVLEAAERAAAHASGRVLLSLREHLQNRLAPTDRIFTNRH
                     GTAWAAADTRSPLDEEALGRTLAVLDEEITRRLPDPGELIVDPAVLDVALPLSGKSAAP
                     GLGVLPRGSLSPVDGELLRFFVYWRQARRSTDYDLSALMLDATYDNPTHISWTSYGNDF
                     ATYSGDLTDAADGASEFIDIRLPHATQPIVIPQVHVYAGERFDEAAEAFFGFMTRDAAQ
                     EGRPFEPRTVRMKSDLRGSGRVALPLVFLRGDDGAWRVKWLHLHLSGHPAFNQVEGNRV
                     TTSRLVRSIVERDYLRVGYLAGLLRAKPSEGGHVTYIGLDAPAGLPEGARVFTPATLHE
                     LIPA"
     gene            6036..6926
                     /locus_tag="F5972_RS17010"
                     /old_locus_tag="F5972_17010"
     CDS             6036..6926
                     /GO_function="GO:0015666 - restriction
                     endodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0009307 - DNA restriction-modification
                     system [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_150934438.1"
                     /locus_tag="F5972_RS17010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17010"
                     /product="phosphorothioated DNA-binding restriction
                     endonuclease"
                     /protein_id="WP_150934438.1"
                     /transl_table=11
                     /translation="MDWVERVACIKPWKRHGERAPHKPLLLLYALGRFQRDGGRPIPFS
                     SAEAELGLLLKEFGPPRRTSPGYPFHHLTNDYGLWLVETVDGPGSPGSELGRLREAQAT
                     GRLHPDLLRALTDDSGLVARLARHLLDTNFEPSLHPDICRHVGLELNDQVTTAEQASLS
                     TARRDPAFRERVLVAYEYCCAFCAYEGWLDGTAVGLDAAHVRWWAFDGPDDVANGLCLC
                     AIHHKLFDKGVLGLTPERTIAVSRKFVSRSPAAAQMVLSLAGHPLREPQRGLDPVDGGH
                     IDWHTRQVFRAPARH"
     misc_feature    6834..6836
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(6946..7947)
                     /locus_tag="F5972_RS17015"
                     /old_locus_tag="F5972_17015"
     CDS             complement(6946..7947)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS17015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_17015"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_150934439.1"
                     /transl_table=11
                     /translation="MAGPFDAPPQPDRLTTTAEFVAALGSLRQWSGRTFRQLTAAAKAN
                     GDALPASTIAGALGRATLPREEFVAAFVRACGLGEAESVRWVAARKRLAAELPPLSSVA
                     PGDPAAQVRPPEGPARRGPQWPALVGVGAGVLLVLFAVVSVLPSLYDPQPGGGTPGPSP
                     FRAAATSLNDRMPSDGWYHMVPAHVAEDGLCIGEGRERSGRTDRPLAVQRPCAGLVPDT
                     FLRAVGDGAWQIEWHHPVEGAGCLTVDEALKAPGALIAPDYCTGVPYQQFLLKPAGSGF
                     VVRPLHSGLCVGALYGESDMRAGAEIAQKTCTGRRDQIFLFRPAPAPTWTPR"
     protocluster    7615..30168
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[17614:20168](-)"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(17615..20168)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((YcaO or TIGR03604) and TfuA)"
                     /neighbourhood="10000"
                     /product="thioamitides"
                     /protocluster_number="2"
     misc_feature    complement(7996..8005)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.45"
                     /tool="antismash"
     gene            complement(8056..9381)
                     /locus_tag="F5972_RS17020"
                     /old_locus_tag="F5972_17020"
     CDS             complement(8056..9381)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF022432.5"
                     /locus_tag="F5972_RS17020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17020"
                     /product="DUF2786 domain-containing protein"
                     /protein_id="WP_150934440.1"
                     /transl_table=11
                     /translation="MGRADRERRRAGENERGSRWQGRPGGARAFPRGRAEPPPEEMVAE
                     LLSAAVDARLHAEAPQFPRLVETLTGDPGLRPVVDRALLGMLGEHLARAWRNGWMPADV
                     VRLVGRRFGARHVCLVTDAVAAEMRAYAPATVDERWHDQLTALDATVWWGRDEEYLRED
                     GDRAAMVARALEVIILLARLQPLERLCPPPGSARRTARAAGRVDERMLTRVRALLAKAE
                     STEFEAEAETFTAAAQSLMARYSIDAALLAAGEANRTGDEPQGRRLGIDAPYEGPKAVL
                     LDVIASANHCRSIWSRHLGFATVLGFPAELAAVEVLFTSLLVQATTAMRQAGARRDGAG
                     RSRTRSFRQSFLAAYAYRIGERLHEAAGEAVRQATAETGRDLLPVLAARDEVVDAAMEK
                     MFPGLSMVRTGSVSNREGWISGRAAADQAVLDVHPKIPSGRS"
     gene            9638..9916
                     /locus_tag="F5972_RS17025"
                     /old_locus_tag="F5972_17025"
     CDS             9638..9916
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF045559.1"
                     /locus_tag="F5972_RS17025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17025"
                     /product="StsA-related sactipeptide RiPP"
                     /protein_id="WP_150934441.1"
                     /transl_table=11
                     /translation="MAFDPREALREAGVLNSPLAAEVEAAFATLTREEVDLLISLKDKL
                     PNALPGVLAHAGAGGEWSRPEVEAHTVPVEAKCLCGAWSGSGSGAAE"
     gene            10001..11476
                     /gene="stsB"
                     /locus_tag="F5972_RS17030"
                     /old_locus_tag="F5972_17030"
     CDS             10001..11476
                     /codon_start=1
                     /gene="stsB"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PTHR43273"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF045574.1"
                     /locus_tag="F5972_RS17030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17030"
                     /product="StsB family radical SAM/SPASM domain sactipeptide
                     maturase"
                     /protein_id="WP_225311562.1"
                     /sec_met_domain="PTHR43273 (E-value: 2e-42, bitscore:
                     140.7, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.1e-11, bitscore: 40.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.3e-23, bitscore: 79.4,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 1.2e-09, bitscore: 33.2,
                     seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 2.4e-14, bitscore:
                     48.7, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.7e-09, bitscore: 33.3,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMSGKLARNRSLIEVPADLTYFVHDDEYLVVNPQVGGRCVLDARE
                     FAVLEALARPGAGGEQARLDETATGESDETDRTLAKLILNYIVYYNGNRPALSFKEPSL
                     RQVYYAITDGCNLRCPYCYASSEKCLPGELTTAESLDLVSQVAAFGASTMIFTGGEPML
                     RKDLFQIVEHANESGLTSNIITNATMIRKPAQAKRFAELFGMVTVSVDGGTAETHDRTR
                     GAGSFARTYRALQLLNEAGVVPRINHIVTSDNVDELEDFARFADGIEVHSIRLMYHNDL
                     GRGESDEYDFGWDDHMRIQRLTWTSPAAGKLLPDGPRPVTPCSVKANCGMGGNEIYINS
                     LGDVYPCKLVTGRSHHAGNVRLQSLAEIFGGPLLRGMRTSTVLGGDYHADCAKCYIKAS
                     CGGGCRASHMSESKDLRRNSRHQCRILRHGVATQLWLEAGVDRSELATKDREMTTPRLV
                     VNGDVHPVFDDWKTYVRPSPSIKVGELLPITPV"
     gene            11488..11790
                     /locus_tag="F5972_RS37285"
     CDS             11488..11790
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF017239.5"
                     /locus_tag="F5972_RS37285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="PqqD family protein"
                     /protein_id="WP_191910163.1"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 8.5e-14,
                     bitscore: 46.6, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 7.6e-10, bitscore: 34.2,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLRISEAVIWQETGEGVSLYHTETGDFHSLNDTGSRIWKLVASD
                     GEREPVMFKLSREFAGSNSAMSKQIVADVRDFIGTMIEQGLIEEVPSEKAEKALT"
     aSDomain        11491..11754
                     /aSDomain="Stand_Alone_Lasso_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="Stand-alone RRE protein in a lasso peptide
                     cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F5972_RS37285_Stand_Alone_Lasso_RRE.1
                     "
                     /evalue="4.00E-15"
                     /identifier="RREFam002.1"
                     /label="F5972_RS37285"
                     /locus_tag="F5972_RS37285"
                     /protein_end="89"
                     /protein_start="1"
                     /score="46.6"
                     /tool="antismash"
                     /translation="SLRISEAVIWQETGEGVSLYHTETGDFHSLNDTGSRIWKLVASDG
                     EREPVMFKLSREFAGSNSAMSKQIVADVRDFIGTMIEQGLIEE"
     gene            11909..13516
                     /locus_tag="F5972_RS37290"
     CDS             11909..13516
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1246: monooxygenase FAD-binding"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF024240.5"
                     /locus_tag="F5972_RS37290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_191910164.1"
                     /transl_table=11
                     /translation="MSRAVVLGGGFAGVLAAAVLARHADEVVVVEGDHYPSGPRPRRGL
                     PQAHHSHVLVAGGARALEALLPGTVGALLARGAHLRGLPGDALILTADGWFRRMRTDAH
                     LISCTRGLLDEVVRRRALGGGTVAVWEDTRALGLLGDAARVGGVSVSRRGAPPETVRAD
                     LVVDATGRRSASPRWLAEIGAGDVEESAVATGLAYATRLYEAPADLAEAIPAIMLHPGP
                     DPGRPARGATLFPVEDGRWVVTLTGTRGGEPPTEEQGFAAFARTLRDPLVADLMAEATP
                     LGLIRPYRDTVNRRRFFERARLPAGFAVIGDAAVAVNPIHSHGMSVAARCALRLDEELL
                     RHGGIGPALFSGLQSALAAEAEQSWRMAVEADGERAGAGTGERTEGTGAGAGARAGTVD
                     TAGAGAADRAGAGAAGRAGAGAAGRAGAGDVERADARAGRDGAPRRAPNAFEREIRTRL
                     AQAKLSSPRIAAKLFAAQTLLSDDTAPDRSEIAQVLTGRPEPLLTSEEAIGQYPGLAAW
                     LRSRLATATATATATATR"
     gene            complement(13604..14188)
                     /locus_tag="F5972_RS17040"
                     /old_locus_tag="F5972_17040"
     CDS             complement(13604..14188)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017565922.1"
                     /locus_tag="F5972_RS17040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17040"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_225311563.1"
                     /transl_table=11
                     /translation="MPAYHHGNLRATLLAAAERSLRRDGADRLSLRDLAREAGVSHAAP
                     RRHFPDRQALLDALAESGFARLDQELRAALAEAGEEFGPRLHATAVAYLRFATEDGALL
                     ELMFNRKHREGADRLVAAAAEPFGLMHGLIEQGQAQGVLEPGDPQRAGIVLFATLQGIA
                     TLVNGGLVAPELLDGIVETAVDQFIRGSRRR"
     gene            14254..15162
                     /locus_tag="F5972_RS17045"
                     /old_locus_tag="F5972_17045"
     CDS             14254..15162
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (15-144). E-value: 1.9e-09.
                     Score: 29.6. Matches aSDomain:
                     nrpspksdomains_F5972_RS17045_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013155245.1"
                     /locus_tag="F5972_RS17045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17045"
                     /product="oxidoreductase"
                     /protein_id="WP_150934444.1"
                     /transl_table=11
                     /translation="MTTFTAERIPAMTGRTVVVTGANSGIGRAAAQALAARGARVVLAV
                     RDPAKGHAAAGTMTGDVAVRRLDLADLASVRAFADGFTEPIDVLINNAGLMIPPLGRTA
                     DGFELQFGTNHLGHFALTNLLLPRVRGRVVTVSSGAHRMGRIDFDDLNWERKPYRALPA
                     YAQSKLANLLFTAELHRRLTEAGSPVLATAAHPGLAATNLLGHLDDGRSLLRRLRTAVI
                     NGLAQSGDDGALPTLYAAVADVPGGGYAGPGGLLGRGAPKLVGRSRAARNGALARRLWT
                     VSEELTGVTFPLPATGPAARP"
     CDS_motif       14299..14382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS17045_0001"
                     /evalue="7.50E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="F5972_RS17045"
                     /protein_end="43"
                     /protein_start="15"
                     /score="21.8"
                     /tool="antismash"
                     /translation="TVVVTGANSGIGRAAAQALAARGARVVL"
     aSDomain        14299..14685
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F5972_RS17045_PKS_KR.1"
                     /evalue="1.90E-09"
                     /label="F5972_RS17045_PKS_KR.1"
                     /locus_tag="F5972_RS17045"
                     /protein_end="144"
                     /protein_start="15"
                     /score="29.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TVVVTGANSGIGRAAAQALAARGARVVLAVRDPAKGHAAAGTMTG
                     DVAVRRLDLADLASVRAFADGFTEPIDVLINNAGLMIPPLGRTADGFELQFGTNHLGHF
                     ALTNLLLPRVRGRVVTVSSGAHRMG"
     CDS_motif       15025..15084
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F5972_RS17045_0002"
                     /evalue="2.10E+01"
                     /label="PKSI-KR_m1"
                     /locus_tag="F5972_RS17045"
                     /protein_end="277"
                     /protein_start="257"
                     /score="-2.1"
                     /tool="antismash"
                     /translation="RGAPKLVGRSRAARNGALAR"
     gene            complement(15210..16244)
                     /locus_tag="F5972_RS17050"
                     /old_locus_tag="F5972_17050"
     CDS             complement(15210..16244)
                     /GO_function="GO:0008171 - O-methyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042: O-methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF013087.5"
                     /locus_tag="F5972_RS17050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17050"
                     /product="methyltransferase"
                     /protein_id="WP_150934445.1"
                     /transl_table=11
                     /translation="MSDRPRGLAGQANLSRMAFGYATSQILYAAVRLGVPDLLAEEAVP
                     VARLAERTGSDPGALHRLLRALVVLGVAEEGEPGCFTLTPQGRPLRADHPWSMRSSLLL
                     LGDPATWQAWGALTHSVRTGETAWDHAHGEPLFDHLARHPDLSAVFNRAMREGTERIAP
                     ALPRAYDFTGAQTVVDVGGGNGTLLAAVLAATPGVKGILFDTAEGVAGADEEFRRAGLS
                     DRCVIETGDFFEAVPGGDVMLVKGVLHDWDDRRCVTLLRSCRRSIAADGRLLVLEPVMP
                     SALGTPEAAGAVMSDIAMLVYTGGRERGSAEFGDLLAAAGFDLTEVTPPLGGSEIRILV
                     AHPA"
     gene            complement(16288..17547)
                     /locus_tag="F5972_RS17055"
                     /old_locus_tag="F5972_17055"
     CDS             complement(16288..17547)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012296.5"
                     /locus_tag="F5972_RS17055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17055"
                     /product="cytochrome P450"
                     /protein_id="WP_150934446.1"
                     /sec_met_domain="p450 (E-value: 1.2e-25, bitscore: 85.3,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVTEPGQPSGPAAQLFDPAAARHRPDPHPLFHRMREQAPVYRYV
                     NPGSGRVLWYLTRYADVQRALLDPDVGRQLDRLPPELAAPHRRAEMRDPLAMLRRNVFH
                     LDPPDHTRIRRLMAPAFGARTVAALERRVHRVAGELLDGMAAAGGEADLIRELALPLPV
                     LVVADLLGLPPEDRARLRGWSDEIVGSGDAGRIRRAGLEFAAYANERIDERRAHPGDDL
                     LSRLAEAERTGGISRAELVSSVFQLLLAGDETTVNLIGNGVLELLRHPRQLDRLRARPE
                     LIGSMVEEALRFNGPVGHSRPLYVLADVEIGGTVIPRGDVVVPVLLAANRDPAVFPRPD
                     DFDIARSPNRHLGFGHGAHFCLGAALARLQAVAAIGALVRRFPDIALAVDPAGLEWTPD
                     LFLHGVRRLPLRLRLEAGVA"
     gene            complement(17615..18970)
                     /locus_tag="F5972_RS17060"
                     /old_locus_tag="F5972_17060"
     CDS             complement(17615..18970)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: TfuA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF019429.5"
                     /locus_tag="F5972_RS17060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17060"
                     /product="TfuA-like protein"
                     /protein_id="WP_150934447.1"
                     /sec_met_domain="TfuA (E-value: 3e-42, bitscore: 138.4,
                     seeds: 78, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSPNVVVYAGPTISPDEVRGVVPHARVRPPVARGDLLSETWSPD
                     DTAVIIDGYYREKLAVGHKEILWLIAEGVNVVGAASMGALRAAELSPYGMTGAGTVFDM
                     YTTGEVDGDDEVAVLHGPADLGYPAGTVALVNLRYGCREGARTGRIPAEAGERIVRAAK
                     AMPFAHRTWQELGAAVDGDDRACLETLRRLIGTGEWDVKRLDALDALAALQAAGERRAG
                     GPGERPGGEPEAWAADTALTGITHYEALKWRSRREYAPGRWMTDLDVVTAGRLFGDDYP
                     RLHEETLTGLLTGFAAGRGLDLEAYVRARLGVAEAEPLPPVLAPWLTETERAALPIGEQ
                     LRLVMVRVWPVWQSEDWRPVVLERVRRSGLWQEWSEIVARADEAAERTRGRIAVPPPEI
                     CAKLFLRHWHGKGTSAEVEMARRGFTGPQELGHAVRRFFALDVQNARASGNR"
     gene            complement(19005..20168)
                     /locus_tag="F5972_RS17065"
                     /old_locus_tag="F5972_17065"
     CDS             complement(19005..20168)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     azole-containing-RiPP: YcaO"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     thioamitides: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF014661.5"
                     /locus_tag="F5972_RS17065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17065"
                     /product="YcaO-like family protein"
                     /protein_id="WP_150934448.1"
                     /sec_met_domain="YcaO (E-value: 1.8e-65, bitscore: 217.0,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRTETSSHSWLLSLSDETKVRLPGTDRARDPAATLEMAGRAARRA
                     GVTRVADITRLDTLGIPTYQAIRPAARTLAVSQGKGVTADLAKLSAMMESVELWHAEQP
                     MRPVTTASARELAGELGYDVGALPRCAPSLLHDGLPVDWVAARSLADGSPTLVPMELAQ
                     FTLVRRTGWHPPVFFSSTNGLASGNTLTEGVLHALYEVIERDAVTAFMTGGDRGTRVDP
                     RSLGSPVVDDLCVTMERARVRMEVRSLASPTGLPCFLARITCDDYPPPFLGFGCHLSSE
                     IALSRAVTEAAQARLGYIAGSRDDLHANVHDGQGAPRRPEPPQEPGAPITPLHAHESLV
                     DDLDDVVKRATVAFSHAPLVVDLTREDLGVPVVRVLAPGSRVCPEVF"
     gene            complement(20232..21044)
                     /locus_tag="F5972_RS17070"
                     /old_locus_tag="F5972_17070"
     CDS             complement(20232..21044)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type
                     transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF013245.5"
                     /locus_tag="F5972_RS17070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17070"
                     /product="ABC transporter permease"
                     /protein_id="WP_150934449.1"
                     /transl_table=11
                     /translation="MAAGLHFHAAPPAPTARATDLLAVLYREYALLARNRVYLILGLTP
                     MLVYLLLVNTSLSNLVRVVDYKGVSVGFAVFLLPMTLAMSVVSAAATSAMAVFQEEMSG
                     VATQLWSYPMRRSRFLLGKMIAGVSLVLGQTLLGLGVAALIFDLPFGPENWVGLLSALV
                     LSALALNGLYLAAAITITDYQAFMVLSNVSMPVLVFSAPSMYTTESMPTVLQWISVVNP
                     LTYAINGMRDAAVFGVGEAWVDLLVLAVMAVVGYTVGGRALINRARNI"
     gene            complement(21047..21988)
                     /locus_tag="F5972_RS17075"
                     /old_locus_tag="F5972_17075"
     CDS             complement(21047..21988)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012235.5"
                     /locus_tag="F5972_RS17075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17075"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_204288811.1"
                     /transl_table=11
                     /translation="MLRDVVTAVGLTKQYRGSERPAVDDVSFEIAQGETIGLLGPNGAG
                     KTTLIKMICGVTTPTSGEIRVFDADPVRQPVLAKSGIGAMHQSGPFDMMLPALDNLRIA
                     ARFRGLRWRDVRPWAFEVADFLGVTGSMQRLVFQMSGGQRQRLQLVRALLTIPRLLILD
                     EPSAGLDVAGRRQVERFVTWLREEHGVTVLWTSHHIDELERNSQRVLVVDRGRVVRFAK
                     PRELVEEFGSTHLLVTVEDPASGGLVAAWAESAGLRAKAEDNEVRIDDAKARDLLPELS
                     RYCQDHAVAITGVSTAVDSLEEVFLRMTGNEG"
     misc_feature    complement(21984..22004)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 20.42"
                     /tool="antismash"
     misc_feature    complement(22090..22105)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            22261..22512
                     /locus_tag="F5972_RS17080"
                     /old_locus_tag="F5972_17080"
     CDS             22261..22512
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012422.5"
                     /locus_tag="F5972_RS17080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17080"
                     /product="LuxR C-terminal-related transcriptional
                     regulator"
                     /protein_id="WP_150934450.1"
                     /transl_table=11
                     /translation="MDLVSDGLINDRDRWLIVMLARGYTTTKIAHEMHLSRYTVAERIS
                     KLLLQFACSNRSQLVAYFYAHRLLHVGIWPPSVSDALG"
     gene            22926..>23756
                     /locus_tag="F5972_RS39370"
                     /pseudo=""
     CDS             22926..>23756
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024295.5"
                     /locus_tag="F5972_RS39370"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /product="glycoside hydrolase family 44 protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNFADETLAKELRLPVRRWGGNATTRYNYLYDTSNRASDWFFENI
                     AEDNTNPSALPDGSSVDKFVEQDRRTGTDTILTMPLIGWAPKGRDASCGFSVAKYGPQQ
                     QTDQWRPDCGNGVKPDGTKITGNDPHDTSVEAGASYVKDWIAHLTGKYGTAASGGVKFY
                     SLDNEPDIWHGTHRDVHPEGASSVELRDKGYLIGAAIKTADPGAKTLGPVGWGWSSWDY
                     SGLDQEVCGRTNCWSNPPDKAARDGLPFTTWYLRQMKKYEDTNHLRVLDYFDEHF"
     gene            complement(24302..24631)
                     /locus_tag="F5972_RS39375"
     CDS             complement(24302..24631)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF046825.1"
                     /locus_tag="F5972_RS39375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_404803060.1"
                     /transl_table=11
                     /translation="MVYVTEQEPGGVGVPLGDGEGDGDRVGEALGEGLGLREGDTLGDG
                     ETLGEGDALGDGEALGEGLGDVTVPAGTTIVLIEFAGNVPVKPLAPTWTSASLLMAEVS
                     AAPYR"
     gene            24618..24926
                     /locus_tag="F5972_RS39380"
     CDS             24618..24926
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012762.5"
                     /locus_tag="F5972_RS39380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_404803061.1"
                     /transl_table=11
                     /translation="MTYTITNQWPGGFQADVRIVNRGASAVKGWQLGWTFGNGQTVNQL
                     WDGSYTQSGAKVTVTNASYNASIAANGGSVSFGFIGGWNGSNTAPKQFTLNGASCGA"
     gene            25040..25408
                     /locus_tag="F5972_RS17090"
                     /old_locus_tag="F5972_17090"
     CDS             25040..25408
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS17090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_17090"
                     /product="hypothetical protein"
                     /protein_id="WP_150934451.1"
                     /transl_table=11
                     /translation="MDDEIGFLEGPFDSDEAADAVAEIEVSDGRSARLRAQRDAGLDRV
                     VASVRLQEFLVFGTLATGPYAEQVSRGRLTAEAWIDFGHPHLLPDEDVEREVAADLHRA
                     LSAAGRYLGLASLPPLPA"
     misc_feature    25062..25077
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 21.03"
                     /tool="antismash"
     gene            complement(25419..26996)
                     /locus_tag="F5972_RS38160"
     CDS             complement(25419..26996)
                     /EC_number="2.7.11.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012298.5"
                     /locus_tag="F5972_RS38160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="serine/threonine-protein kinase"
                     /protein_id="WP_225311565.1"
                     /sec_met_domain="Pkinase (E-value: 3.3e-41, bitscore:
                     136.5, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 2e-07, bitscore: 26.3,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQPLEPGDPGRLGSYRITGRIGEGGQGVVYLGEGESGGLVAVKL
                     FHARLGGDAAAHDAFVRETEVARRVARFCTAQVLESGVDGGRPYIVSEYVQGHALSQVV
                     AAHGPMSGGALERLAIATATALVALHDAGVVHRDFKPHNVLIGPDGPRVIDFGIARALV
                     GAGTVTSQVVGTPAYMAPEQFTAGELGFALDVFAWASTMVFAATGRAPFGADAIPAIIN
                     RILNHEPDLDGVEAPLRDLLTACLAKDPGRRPAAREILDRLVRPRHDAPAAPTPAPIIP
                     VALTPAAITPATMPPGPSASGPVEAPGRSRRGRVVGTVVAAVVVVAALVAAVALLPSLR
                     RPSAGSGPSLTERAAAAGTAPAAASAGAGGGASPSGTPSRTPASRSASPASSPRPRVSR
                     PTAGPVVTRTAPTRTITARPTVRRSKTATPVPADPPASKSPKPSPASALRLVELGGGHF
                     TEYCVSLGWEWVEYRESPTPGAYCVKRKGDTMYLSQSQRDAGCRWRFHDPKAFHRFKGK
                     SNYCYTYR"
     gene            complement(27193..29559)
                     /locus_tag="F5972_RS17100"
                     /old_locus_tag="F5972_17100"
     CDS             complement(27193..29559)
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012551.5"
                     /locus_tag="F5972_RS17100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_17100"
                     /product="PHB depolymerase family esterase"
                     /protein_id="WP_150934452.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 5.1e-12, bitscore:
                     40.9, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRRRIVAVLAAMLMPVVALAALLVAQPAAAASLTRVTSFGNNPSN
                     LNMYIYVPDRVASRPALLVAVHYCTGTASALYSGYFRDYVTAADQYGYIIVFPEATRSG
                     QCFDVYSPQALRRGGGSDPVGIMSMVDYARSRYNVDPGRIYVSGVSSGAMMTNVLAAEY
                     PDVFKAGSAFMGVPAGCFATTDGSTWNSQCANGQVSKTAQQWGDLARSMYSGYTGSYPR
                     MQLWHGTTDSTLHYNNFGEEIKQWTNLNGVSQTPAATDTPSSGWTRTRYGGNGTQPPVE
                     GVSVSGQGHSLPLNGQIAYAINFLGLNSTTPSSPSPTPSPTPPNSPSPSPSVSPSAGPP
                     ASTLGEAAARSGRYFGTAISASKLGDSQYTTIANREFNMITAENEMKIDATEPNRGQFT
                     FTNADRIYNWAVQNGKRVRGHTLAWHQQQPGWMQSLSGSSLRQAMIDHINGVMSHYKGK
                     IYAWDVVNEAFDDSNGGRRDSNLQRTGNDWIEVAFRTARAADPDAKLCYNDYNTDNWTW
                     AKTQGVYNMVKDFKQRGVPIDCVGFQSHFNSGSPYNSNYRTTLSSFAALGVDVQITELD
                     IQGASAQTYANVVNDCLAVPRCNGITVWGVRDSDSWRSGDTPLLFDGNGNKKAAYTSVL
                     DALNAAVPSTSPSPTPPVSPSATPSDSPSATPSDSPSPTPSDSPSPSPSESPTVEPGGC
                     SATMRTVNSWPGGFQSEVTVSAGGSAIRGWTVSWNWSGSASITQLWNGVRSGSGSAVTV
                     RNESYNGTVAAGGTTTFGFTGSGSAETPSLTCGAS"
     misc_feature    complement(29494..29496)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    29687..29701
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 18.3"
                     /tool="antismash"
     misc_feature    complement(29694..29712)
                     /note="TFBS match to HgtR, Hydrogen-dependent regulator,
                     confidence: weak, score: 17.31"
                     /tool="antismash"
     misc_feature    complement(29801..29815)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.89"
                     /tool="antismash"
     misc_feature    complement(29824..29840)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.87"
                     /tool="antismash"
ORIGIN
        1 gcgcggtgtg gccgccgaac ggcttctcca ccgcctccgg cagggacagg cagatctccc
       61 ggacccgcgc caccgcgttc tcgtcaccca ccgcgcccgt ccctctctcc cgactcctcg
      121 ccgggccgcc ccggcaggcg cccgtaccgc cccagtatgg ccgtgccggc cgtcacgcgc
      181 gtgccgcggt tcggcgtact gtccggtgga cggaccacgc cctgacccga ggactccgca
      241 tgccgaagct caaccgcccc ccgctgccgg tcgtcgtcga gcacgacagc cccatgccga
      301 tgcgggacgg caccgtcctg cgcggctccg tccaccgccc ggcggacggc ggtccgttcc
      361 cggcgctgct cgtgcgcacg ccgtacggcg aggactcgtt ccgtacggag ccggtgctgc
      421 cggccctgcg ggccgggttc gcggtcgtgc tgcagcactg ccgggggcgc ggcaccagcg
      481 acggcgagtt ccggccgtgg ctggacgagg gcgccgacgg ccacgacacg atcggctgga
      541 tcacctcaca gccctggtcg aacggcgagg tcgtgatgag cggcatgtcc tatctcgccg
      601 gatgcgcgtt gcaggcggcg gccacccgtc cgcccgggct gaaggcggtg gtcgcggcga
      661 tgacgccgca cgacttccac gacggcctga agtatcacgg cggggcctta gcgctgggat
      721 cggccctgaa ctggggggcg ttccaggcga tgctcggcct gctgcacgcg gcggaggcgg
      781 gcgaggacac cggcgcggcc ctcgccgagg tgctgcgggt cctggccgac caggagaccg
      841 ccgtacgcac cctgcccgtc ggcgacgtcc cgggcattcc gtggtggcac gactggacct
      901 cgcacgtgac gcgcgacgcg tactgggaag gcctggccga gacgctgcgg cacgaccgcg
      961 tcgaggtgcc ggtgatgcac gtggcgggct ggttcgacct gttcctcgcg gggacgctgg
     1021 agaaccaccg ccgcctgggc ggcccgctgg tcgtcgggcc gtggtcccat ctcgcgccgg
     1081 gcgccggcgg caccgggcgg ctgttcttcg gcgcggccgc gtcggcgcag gcgatcggcc
     1141 tggaggaacg gcagatggcc ttcctcgcgg gcaaggacga cggccccgcg gtgcggatct
     1201 tcgtgatggg cgacgacgtc tggcgggacg aggaggcctg gccgctggag cgcgccgtcg
     1261 acacccccta ctacctgcac gcggacggcc tgctctcccc cgagccgccc tcggcggcgg
     1321 agccggccgt cttcgtcttc gacccgcgcg accccgtccc gaccgtcggc ggcccgaccc
     1381 tgctggccga tcccaccaac gtcggtcccc aggaccagcg ggacgtggaa cggcggccgg
     1441 acgtgctctg ttattcgacg gaggtgctcg cctccgacgt cgaggtgacc ggcccggtgt
     1501 cggtgaccct ccgcgcggag acctcggccg cctcgaccga ctggacggcc aagctcgtgg
     1561 acgtccatcc ggacggccgg gcgatgagcg tgatcgacgg catcgtccgc gttctcgcgc
     1621 cgtccgggac gttcgtcatc gatctggtcg ccaccagcca ggtcttcagg gccggccatc
     1681 gcatcagggt ggagatatcc agctccaact tcccccgctt cgaccgcaac cccggcaccg
     1741 gccgccccgg cagcggagag gcggacctgg tcgtccagca ccagaaggtc caccccgact
     1801 cgtacgtcac cctcccgatc gtcccccgct gagcggctcc gcgggccggc cctcttccag
     1861 gtgggacgcc gcacacgaac gccgaatcgc catcgctgcc agacaggcga ttcggccttc
     1921 ggtggacggt ctgggtcaga ggtcgttgtt caggagggcg tcggcggact ggaccgtggc
     1981 ggcggcgcgg atccacgcgt ccagccggtc gaggtcacga cacttcctga tcttgtcgtt
     2041 gagctcgtcg ggcacctcga tcccgcgggc ggccagcacg gtcaggatcg cctcggtctt
     2101 gccttcggtc tggcccttgg cgatgttctc gcgggcccag tcgctgaggt attcgtagct
     2161 ctctgtcttc atgtgcctct ccaagtgatc ccagatctct cgggggagcg ccgcacgcac
     2221 catgtcagcg tacatacccc cctggtcacg gtcgagattg tgcagcgcgg cgaacagcgc
     2281 gttgaggata tcggggccct gcggcgtggc ggcgtgatgg atcaccgaca gcatcgccag
     2341 ttcgatgtcg tcggccgcct ggcccgggtc ggtgatgacg gggacttcgt cgggacccgc
     2401 gaccagcggc gtcggcacca gcccggggtg cccgagctcg atcggccggg cgcaccaccg
     2461 ggcgaccgcc gcctccgggc agatcaccag cagcatgacc gggcattcca ggcgggtgcg
     2521 caggctgacg aggtacatcg gccaggacca gagcttgccg ggatcgcggc ctcgctgcac
     2581 ctccacgatc acggcgacca ccggctcggg gtcggcgccc ggacgcttgc gccggaacac
     2641 gatgaccgag tccgcgtgac gagaggcggg cgtgacctcg gtgaggtcgg ccgactccac
     2701 cgccgcgtag tcgaagtccg ggagctgtac gtcaagggag cgggccagaa gtccggcggc
     2761 cagatcgggc cgttcctgga acaggcgtat caccgcttcg tgttcaatcg taagcatgga
     2821 gtgacaatag gagcgtgccg aaggcggaca ttgatcgtca ttactgatag ttatcaaaca
     2881 gttaccgtcg atgaatggcg gccgcgcggt cgctatcgga ggtaggccgg ggggacgtgg
     2941 tcgaccagcc agacgccgtt ggcgctcagc cggaaccgat gcccggccgc gtgcatcgcc
     3001 gccgcgtcca cgacgaggac gaccggcctg cccctgcgcg caccgacgcg ggtggcggtc
     3061 tcccggtccg gcgacaggtg gacgtggtga cgttccatcg gccgcaggcc ctcctcgcgg
     3121 atcgcctcca cgttccgggc gaccgtgccg tgatagagga tcgggggtgg ctcggccacc
     3181 gggaggtcga ggtcgacggc caccgagtgc ccctgactgg cccggatgcg ctcgccctcg
     3241 atcacgtacc gccgcttgtc gttgtcggcg accacctgct ccagttcggc acgcgagatc
     3301 gggaacccgt gcgcggccgc cgccgtcagc agcgtgtcga cggcgaccca gccgtgcgcg
     3361 tccagttcga tgccgatgcg ctcgggttcg tggcgcagat gcttggccag gtacttcgag
     3421 acccgcacca gcctgcgttc gtccatcagc gtctcccggt gtcctcgatg agcccgcgga
     3481 gcgtcgcggg gaccggccgg acggccggtg aggagggctc ggaggctgga tgtgccagcg
     3541 ggcccgtcac gggcccacct ggaatcgaac caggaggaga aggaagcccc cgaatggcct
     3601 caccgggccg gagcgcgagg aaagcgggcg gactagacag gcgcccttgc gggcaaaccg
     3661 gttcccaaag aggtagaagg aagccctccc atggcctcgc gatccagacg atatcaggcg
     3721 gggatcagct cgtgcagggt cgcgggcgtg aagacgcgtg ccccctccgg caggccggcg
     3781 ggtgcgtcga gcccgatgta cgtgacgtgc ccgccctcgg acggcttggc ccgcagcagg
     3841 ccggccaggt agccgactcg caggtagtcc cgctccacga tcgagcgtac gagtcgcgac
     3901 gtggtgaccc ggttgccctc cacctggttg aacgccggat ggccggacag gtggagatgc
     3961 agccacttca cccgccacgc tccgtcgtcc ccgcgcagga acaccagtgg cagcgcgacg
     4021 cggccggacc cgcgcaggtc ggacttcatc cgcacggtgc gcggctcgaa cggcctgccc
     4081 tcctgcgcgg cgtccctggt catgaagccg aagaacgcct cggcggcctc gtcgaaccgc
     4141 tcccccgcgt agacgtggac ctgggggatg acgatcggct gggtcgcgtg cggaagtcgt
     4201 atgtcgatga actccgacgc gccgtcggcg gcgtcggtga ggtcacccga gtaggtcgcg
     4261 aagtcgttgc cgtacgacgt ccacgagatg tgcgtcgggt tgtcataggt ggcgtcgagc
     4321 atgagcgcgg acaggtcgta gtcggtgctc cgccgggcct gccgccagta gacgaagaac
     4381 cggagcagct caccgtccac gggtgacagc gagccgcggg gcagcacccc gagcccgggc
     4441 gcggcgctct tgcccgacag gggcagcgcc acgtcgagca cggcggggtc gacgatcagt
     4501 tcgcccgggt cggggaggcg gcgggtgatc tcctcgtcga ggacggcgag ggtccggccg
     4561 agcgcctcct cgtcgagcgg agaccgggtg tcggcggccg cccacgccgt accgtgccgg
     4621 ttggtgaaga tccggtccgt cggggcgagc cggttctgca ggtgctcgcg cagggagagc
     4681 agcacgcggc cggaggcgtg cgcggcggcc cgctccgccg cctccagcac ggccgggccg
     4741 ccacccgtcc gcagcaggtg gtcgaggcgg cgcagcagcg cgccgggcgt gtgctccagc
     4801 agggcgacgg cgtcggcggt acggccctcg gccagcgcgg cctcgacccg gccgccgaag
     4861 ctcgccgcct tacgcgcacc cctggccacc tcgaagacct ggaccgctcg ggggtactgc
     4921 gggtactcgt gcgggtgcag ccgctcgccg agccgcttcc actgctcccg gtggcggagc
     4981 acgtcgccgt gcttggcggc cggcacggcg tccagggcgg ccagcaggat ccggcgctcg
     5041 gcgcggcgga aggagcgcag gcgggcaggg atggacaggg tgacgtcgcc gccggagcag
     5101 agcgcggcca ccctgagcac gtccgtcaca gtgtcgacga gcagcggctg cccggcggcc
     5161 agccgcacct cgttgaggac ggcccggttc tcgcgtacgg ggacatgctc gggccggtcg
     5221 ccggcgcaga aggcggcgag cgcgcgcaga gccgtgaggt cctcggcggc gagcgggacc
     5281 tcggagccgg cgagcgagaa gtagagctcg cacgcctcgt cccggaggct cccgcccagc
     5341 tcaagcacgg tcacccggtc cctggccagg gggatcagct cgtcgtgcgc ggccagcagg
     5401 tcggcgtagg tgtgctgata gcggccgtac cgcggcagat cgagcagatt gagggtgccc
     5461 ggctggagcc gggcggcggc gaccgggtcg agcatggcct cgcgcagcag ccccgcccag
     5521 aagtccagcg tgtccgggac gttcctcgga aagtcgacga agtaggcgtt gtgctcgaca
     5581 tggtcgccga ccaggcggcg gacggcggcc aggacccgca gcccgaggtc gatcacctgc
     5641 tccccgggca gccgggccag gcggtcgagc agcgccggcg agcacgtgaa gccgacgctg
     5701 agcagcgccg cgtcgagctg ccgggcggcc acctcacccc aaccgggcgt gccgtccccc
     5761 tccacgtcga cgggaacgcg caggcgccgg gcaatgacga gatcttccac gcaggcacga
     5821 tatagggcca ctacaggcgc ctcgccactc gaattccgag ccgcgtcaac ggtgaccggc
     5881 cgttgtccct ccgccggcga ggaggtccgg cgcctccgcg agtgggaggc tctggaatgg
     5941 catctcgacg aggtgctccc cggagcgtga cgcgcgcgta tcgactcgga cacaaggcgc
     6001 ccagcagggg cgaagatcac cgtagggtgc cggtcatgga ctgggtcgag cgcgtcgcct
     6061 gcatcaagcc ctggaagcgg cacggcgagc gggcgccgca caagccgctc ctgctgctct
     6121 acgccctcgg gcggttccag cgcgacggcg gccggccgat ccccttcagc tccgccgagg
     6181 ccgagctcgg tctcctgctc aaggagttcg ggccgccacg gaggaccagt cccggttatc
     6241 ccttccatca cctgacgaac gactacggtc tctggctggt cgagaccgtg gacggtccgg
     6301 gaagccccgg ctccgagctc gggcggctgc gcgaggccca ggccaccgga cggctccatc
     6361 ccgacctgct gcgcgccctg accgacgact ccggtctcgt cgcacggctc gcgcggcacc
     6421 tgctggacac caacttcgag ccgtctctgc atccggacat ctgccgccac gtcggcctcg
     6481 aactgaacga ccaggtcacc accgccgagc aggcctctct ttccacggcc cgccgggacc
     6541 cggcgttccg ggagcgcgtg ctcgtggcgt acgagtactg ctgcgccttc tgcgcgtacg
     6601 aagggtggct ggacggcacg gcggtcggcc tggacgccgc gcacgtccgc tggtgggcct
     6661 tcgacgggcc ggacgacgtg gccaacgggc tgtgcctgtg cgcgatccac cacaagctgt
     6721 tcgacaaggg cgtcctcggg ctcactccgg agcgcacgat cgccgtctcc cggaagttcg
     6781 tgagccgcag cccggccgcc gcgcagatgg tcctctccct ggccggacac cccttacggg
     6841 aacctcagcg cgggctcgac cccgtcgacg gcggccacat cgactggcac acgcggcagg
     6901 tgttccgcgc acccgcccgg cactgacggg ccgcctgccg ccgcgtcagc gtggcgtcca
     6961 ggtcggcgcg ggcgccggac ggaagaggaa gatctggtcg cgccgtcccg tgcaggtctt
     7021 ctgggcgatc tccgcccccg cccgcatgtc ggactcgccg tacagcgcgc cgacgcacag
     7081 gccgctgtgc aggggacgca cgacgaatcc cgatccggcg ggcttcagca ggaactgctg
     7141 atacggcacc cccgtgcagt agtccggggc gatcagcgcg ccgggagcct tcagcgcctc
     7201 gtccacggtg aggcagccgg cgccctctac gggatgatgc cactcgatct gccatgcacc
     7261 gtcaccgacc gcacgcagaa aggtgtccgg gaccaggccc gcgcagggac gctgcacggc
     7321 cagcgggcga tccgtccttc cgctgcgctc gcgtccctcc ccgatgcaca ggccgtcctc
     7381 cgcgacgtgc gcgggaacca tgtgatacca cccgtcggac ggcatgcggt cgttgaggga
     7441 ggtcgcggcg gcgcggaagg gtgagggccc cggggtcccg ccaccgggct gggggtcgta
     7501 gagcgacggc aggaccgaga ccaccgcgaa aagcaccagg aggacacccg ctcccactcc
     7561 caccagggcc ggccactgcg gccctcgtcg cgccgggccc tctggcggac gaacctgagc
     7621 ggcggggtcg ccgggggcga cggacgagag cggcggcagc tcggcggcca ggcgcttcct
     7681 cgccgccacc catcgaaccg actccgcctc gccgagcccg cacgcccgta cgaacgcggc
     7741 cacgaactcc tctcgcggga gggtcgcccg ccccagggcg ccggcgatgg tgctggcggg
     7801 cagcgcgtcg ccgttcgcct tcgcggcagc cgtgagctgc cggaaggtcc ggccggacca
     7861 ctggcgcaga ctgcccaggg cggcgacgaa ctcggcggtc gtggtgagcc tgtcgggctg
     7921 cggcggcgcg tcgaacggac ctgccacgac gattccccca agccacggtc cagcgtcgat
     7981 ccgggcgaaa cactaacaaa aatcagtggt gcgaggcggc ctgtcgagtc aacggcctcc
     8041 gtccggcgag ccctctcacg agcggccgga agggatcttc ggatggacgt ccagcacggc
     8101 ctggtcggcg gcggcccggc cggagatcca gccctcgcgg ttgctgaccg agcccgtcct
     8161 gaccatgctc agcccgggaa acatcttctc catcgccgcg tcgaccacct catctctggc
     8221 cgccagcacc ggcagcaggt ctctgccggt ctcggctgtc gcctgcctga ccgcctcccc
     8281 cgccgcctcg tgcagccgtt ccccgatccg gtaggcgtag gcggcgagga acgactgccg
     8341 gaacgaccgc gtgcgggacc ggccggcgcc gtcccggcgt gcgccggcct gccgcatcgc
     8401 ggtggtggcc tgcaccagca gggaggtgaa cagcacctcc accgccgcca gttcggccgg
     8461 gaaccccagc acggtggcga agccgaggtg gcggctccag atcgaccggc agtggttggc
     8521 cgaggcgatg acgtccagca gcaccgcctt gggcccctcg tagggcgcgt cgatccccag
     8581 gcgccgcccc tgcggttcgt cgccggtacg gttcgcctct ccggcggcca gcagcgcggc
     8641 gtcgatgctg tagcgggcca tcagcgactg ggcggcggcg gtgaacgtct cggcctcggc
     8701 ctcgaactcc gtcgactcgg ccttggccag cagcgcccgc acccgcgtca gcatccgctc
     8761 gtccacccgc ccggccgccc gggccgtacg gcgtgccgaa ccgggcggcg ggcacagccg
     8821 ttccagcggc tgcagcctcg cgagcaggat gatcacctcc agcgcccggg cgaccatcgc
     8881 ggcccggtcg ccgtcctcgc gcaggtattc ctcgtctctc ccccaccaga cggtggcgtc
     8941 cagggcggtc agctggtcgt gccagcgctc gtccacggtc gccggggcgt aggcccgcat
     9001 ctcggccgcg acggcgtcgg tgaccaggca cacgtgccgc gccccgaacc gccgccccac
     9061 gagccggacc acgtcggccg gcatccaccc gttccgccag gcccgtgcca ggtgctcgcc
     9121 gagcatgccc agcaacgcgc ggtcgacgac gggccgcagg cccgggtcgc cggtcagcgt
     9181 ctcgacgagc cgcggaaact gcggcgcttc cgcgtgcagt cgcgcgtcca cggcggccga
     9241 cagcagctcg gccaccatct cctccggcgg tggctccgcc cgcccccggg ggaaggcccg
     9301 cgccccgccg ggccgcccct gccaccggct cccgcgctcg ttctccccgg ccctgcgccg
     9361 ctcccggtcc gccctgccca tgtgtcctcc tgcctcggcc ttccccccgc cgggggctca
     9421 cggagttcac gattctgaca gccacccggc cgctccgaag acgttgtcca caggcggccc
     9481 gccggtggat ctcgcgggcc ggccaggccg cgcctcccgg ccgtcacccg acgggcgacg
     9541 agcggctagc cccacgtttg tggggtttct cacccccttc tcacctgcgc atactcgatt
     9601 cacaccgcat tcccccgtca gacagagagg tgaaggcatg gccttcgatc cgagggaagc
     9661 tctgcgtgaa gcgggcgttc tcaacagccc cctggcagcc gaagtcgagg cggcgttcgc
     9721 caccttgacc agggaggaag tcgacctgct catctcgctc aaggacaagc tccccaacgc
     9781 gctgcccggt gtgctggcgc acgccggcgc gggcggcgag tggtcccggc ccgaggtgga
     9841 ggcccacacc gtgccggtcg aggccaagtg cctgtgcgga gcctggtcgg gctccggatc
     9901 cggcgcggcg gagtagtccg ggcagttcgc gggtgcggct ccggccgcgc gtcgcccaca
     9961 gacgtctggg gccgcacctg cggctgggag cgtaagggga atgatgtctg ggaagctcgc
    10021 ccggaaccgc tcgttgatcg aagtgccggc tgacctgacc tacttcgtgc acgacgatga
    10081 gtatctggtc gtcaacccgc aggtgggtgg ccggtgcgtc ctcgacgcgc gcgagttcgc
    10141 cgtcctggag gccctggccc gtcccggggc gggcggggag caggcccgcc tcgacgagac
    10201 ggcgaccggc gagtccgacg agaccgatcg gacgctcgcc aagctcatcc tgaactacat
    10261 cgtctactac aacgggaacc gcccggcact ctccttcaag gagccgtcgc tccgccaggt
    10321 gtattacgcg atcaccgacg gctgcaacct gcgctgcccg tactgctacg cctcctcgga
    10381 gaagtgcctc cccggtgagc tcaccaccgc cgagtcgctc gacctggtct cccaggtcgc
    10441 cgccttcggc gcgagtacca tgatcttcac cggcggcgag ccgatgctcc gcaaggacct
    10501 gttccagatc gtggaacacg ccaacgagag cgggctgacg tcgaacatca tcactaacgc
    10561 cacgatgatc agaaagccgg cgcaggccaa acggttcgcc gagctgttcg gcatggtcac
    10621 ggtgagcgtc gacggcggca cggccgagac ccacgaccgc acccgcgggg ccggctcctt
    10681 cgcccggacc taccgcgccc tccagctgct caacgaggcc ggcgtggtgc cccggatcaa
    10741 ccacatcgtc acctcggaca acgtcgacga gctggaggac ttcgcgaggt tcgccgacgg
    10801 gatcgaggtg cacagcatcc ggctgatgta ccacaacgac ctgggccggg gagagagcga
    10861 cgagtacgac ttcggctggg acgaccacat gcggatccag cggctcacct ggacgtctcc
    10921 cgccgccggc aagctgctgc cggacggccc gcggccggtc acaccgtgct cggtgaaggc
    10981 caactgcggg atgggcggca acgagatcta catcaactcg ctgggcgacg tgtatccgtg
    11041 caagctggtc accgggcggt cgcaccacgc gggcaacgta cggctgcagt cgctggcgga
    11101 gatcttcggc gggccgctcc tgcgcgggat gcgcaccagc accgttctcg gcggcgatta
    11161 ccacgccgac tgcgccaagt gctacatcaa ggcgtcctgc ggcggcgggt gccgggcctc
    11221 gcacatgtcc gagtcgaagg acctgcggcg caacagccgc caccagtgcc ggatcctgcg
    11281 gcacggcgtc gccacgcagc tgtggctcga agccggtgtc gaccggtcgg agctcgccac
    11341 caaggaccgc gagatgacga cgccccgcct ggtcgtcaac ggcgacgtcc accccgtctt
    11401 cgacgactgg aagacctatg tccgcccctc gccctccatc aaggtcggcg agttgcttcc
    11461 catcacgccg gtatagagga ggtcagtgtg tcgctccgga tcagcgaagc cgtgatctgg
    11521 caggagaccg gggagggcgt ctcgctctac cacaccgaga cgggcgactt ccacagcctg
    11581 aacgacacgg gctcgaggat atggaagctc gtggcgagcg acggcgaacg tgagccggtc
    11641 atgttcaagc tgtcccgcga gttcgccggc agcaactccg cgatgagcaa acagatcgtg
    11701 gcggacgtac gcgacttcat cggcacgatg atcgagcagg gcctgatcga ggaggtcccg
    11761 tccgagaagg ccgagaaggc cctcacgtga ccgccctgga cgcggccggc ccgaatgcga
    11821 ccggctcaga cgtgaccgta cgggagccgg ccggaggggc gtgcgtccga accggcgtcg
    11881 tcgtgccgcg tccgccggcc ttccgccgat gagcagggcg gtcgtcctcg gcggtggctt
    11941 cgcgggggtg ctcgccgccg ccgtgctcgc gcgccacgcg gacgaggtcg tggtggtgga
    12001 gggcgatcac tacccgtccg gtccccgccc gcgccggggg ctgccccagg cgcaccacag
    12061 ccacgtgctc gtggccggcg gcgctagggc gctggaggcg ctgctgcccg gcacggtcgg
    12121 cgccctcctc gcccgcggcg cgcatctgcg cggcctcccc ggcgacgccc tgatcctcac
    12181 cgcggacggc tggttccgcc ggatgcgcac cgacgcccac ctgatctcct gcacccgcgg
    12241 gctgctggac gaggtggtac ggcgccgggc actcggcggt ggcaccgtcg cggtgtggga
    12301 ggacacgcgg gcactcggtc tcctcgggga cgcggcccgg gtcggcgggg tctcggtcag
    12361 caggcggggc gcccctcccg agaccgtacg cgcggacctc gtcgtcgacg ccacgggacg
    12421 cagatcggcg tcgccgcggt ggctcgccga gatcggcgcc ggggacgtcg aggagtcggc
    12481 ggtcgccacc ggcctcgcct acgccacacg gctctacgag gcgcccgccg acctcgccga
    12541 ggcgatcccg gcgatcatgc tgcatcccgg gcccgacccg ggacggccgg cccggggagc
    12601 gacgttgttc cccgtcgagg acggccggtg ggtggtcacg ctgaccggca cccggggcgg
    12661 tgagccgccg accgaggagc agggcttcgc ggccttcgcc cgcacgctgc gcgaccccct
    12721 cgtcgccgac ctcatggcgg aggccactcc cctcggcctc atccggccgt accgggacac
    12781 cgtcaaccgg aggcggttct tcgagcgcgc gcgactgccc gccgggttcg ccgtgatcgg
    12841 cgacgcggcc gtcgcggtca atccgatcca ttcgcacggc atgtcggtcg ccgcgcgctg
    12901 cgcgctccgg ctcgacgagg agctgcttcg gcacggcggg atcggaccgg cgctgttctc
    12961 cgggctgcag tccgcgctcg cggcggaggc ggagcagtcc tggcgcatgg cggtcgaggc
    13021 ggacggcgaa cgggccggcg cgggcacagg agagcggact gaaggtaccg gtgccggcgc
    13081 aggtgccagg gcaggcaccg ttgacacagc cggtgcgggt gcggccgaca gggccggtgc
    13141 gggtgccgct ggcagagccg gtgcgggtgc cgctggcaga gccggtgcgg gtgacgtgga
    13201 aagggctgac gcgagggccg gccgcgacgg tgcgccgcga cgcgcgccga acgccttcga
    13261 acgcgagatc cgcacgcgcc tggcgcaggc gaagctgagc agcccgcgga tcgccgccaa
    13321 gctcttcgcc gcccagacgt tgctctccga tgacaccgcg ccggacaggt cggagatcgc
    13381 gcaggtgctg accgggcggc cggagcctct cctcaccagt gaggaggcca tcgggcagta
    13441 tcccggcctg gccgcgtggc tgcgctcgcg tctcgccacc gccaccgcca ccgccaccgc
    13501 caccgccacc cgctgaaagc tccgccacgc gccggaagcg ccgcccccga acccgcgccg
    13561 cctccagacc ccgcgccgcc ccggaacccc gcgccgcgag gcgctaacgg cggcgggatc
    13621 cccggatgaa ctggtcgacg gcggtctcca cgatgccgtc gagcagttcc ggcgccacca
    13681 ggccgccgtt gaccagcgtg gcgatgccct gcaatgtcgc gaacagcacg atccccgcgc
    13741 gctgcgggtc gccgggctcc agcactccct gtgcctgccc ctgctcgatc agaccgtgca
    13801 tcagcccgaa cggctcggcg gcggccgcga cgagccggtc ggcgccctcg cggtgtttgc
    13861 ggttgaacat cagctccagc agcgcgccgt cctcggtcgc gaaccgcagg taggccacgg
    13921 ccgtggcgtg caggcgcggc ccgaactcct cccccgcctc ggcgagcgcg gcgcgcagct
    13981 cctggtcgag ccgggcgaac ccggactcgg cgagcgcgtc cagcagcgcc tgacggtccg
    14041 ggaagtgcct gcggggcgcg gcgtggctga cgcccgcctc acgggccaga tcgcgcagcg
    14101 agagccggtc ggctccgtcc cggcgcaggc tgcgctcggc ggcggcgagc agcgtcgcgc
    14161 gaaggtttcc atggtggtac gcgggcacgg acgtcatcgt agcttgagat gttgtcgttg
    14221 acatctttgt tgccactgcc tactttgttt cccatgacaa catttaccgc cgagcggatc
    14281 cccgccatga ccggtcgcac cgtcgtcgtc accggcgcga acagcggcat cggcagggcc
    14341 gccgcccagg cgctcgccgc caggggcgcc cgcgtcgtgc tcgccgtccg cgaccccgcc
    14401 aagggccacg ccgccgccgg gaccatgacc ggcgacgtcg ccgtgcggcg gctcgacctc
    14461 gccgacctcg cctcggtccg cgcgttcgcc gacggcttca ccgagccgat cgacgtgctg
    14521 atcaacaacg cgggcctgat gatcccgccg ctcgggcgca ccgccgacgg tttcgagctg
    14581 cagttcggca ccaaccacct cgggcacttc gcgctcacga acctgctgct gccgcgcgtc
    14641 cgggggcggg tggtcaccgt ctcctccggc gcgcaccgga tgggccggat cgacttcgac
    14701 gacctcaact gggagcgcaa gccctaccgg gcactccccg cgtacgcgca gtcgaaactg
    14761 gcgaacctgc tgttcaccgc ggagctgcac cgccgcctca ccgaggccgg atcgccggtg
    14821 ctcgcgaccg ccgcgcaccc cggcctggcg gccacgaacc tcctcgggca cctcgacgac
    14881 gggcggtccc tgctacggcg gctccgtacg gccgtcatca acggcctggc gcagagcggt
    14941 gacgacgggg cgctgcccac gctctacgcg gcggtggcgg acgttccggg cggcggctac
    15001 gccggccccg gcggcctgct ggggcgcggc gcgccgaagc tcgtcggccg gtcgagggcc
    15061 gcccggaacg gcgcgctcgc ccgccgcctg tggacggtct ccgaggagct gaccggcgtc
    15121 acgttcccgc tgcccgcgac cgggccggca gcgcggccct gagccggaag ctcgaccgcg
    15181 gagctcgacc aggcaatcga ccggggacct caggcggggt gcgcgacgag gatccggatc
    15241 tccgagccgc cgagcggcgg cgtcacctcg gtcaggtcga acccggccgc ggcgagcagg
    15301 tccccgaact cggcgctgcc gcgttcccgg ccgccggtgt agacgagcat cgcgatgtcg
    15361 ctcatgacgg ccccggccgc ctccggcgtg ccgagggcgg acggcatcac cggctcaagc
    15421 acgagcaggc gcccgtccgc cgcgatcgac cggcggcagc tccgcagcag ggtgacgcag
    15481 cgccggtcgt cccagtcgtg cagcacgccc ttgaccagca tgacgtcgcc cccgggcacg
    15541 gcctcgaaga agtcgccggt ctcgatgaca caccggtccg acaggcccgc ccgccggaac
    15601 tcctcgtcgg cgccggcgac tccctcggcg gtgtcgaaca ggattccctt gacgcccggg
    15661 gttgccgcga gaaccgccgc cagcagcgtg ccgttgccgc cgccgacgtc gaccacggtc
    15721 tgcgcgccgg tgaagtcgta cgccctgggg agcgcgggcg cgatccgttc ggtgccctcg
    15781 cgcatcgccc tgttgaacac cgccgacagg tccgggtggc gggcgaggtg gtcgaacagc
    15841 ggttcgccgt gcgcgtggtc ccacgccgtc tcaccggtcc gcacgctgtg ggtcagcgcg
    15901 ccccacgcct gccatgtcgc cgggtcgccg agcagcagca ggctggagcg catcgaccac
    15961 gggtggtcgg cgcggagcgg ccgtccctgc ggcgtgaggg tgaaacatcc cggctccccc
    16021 tcctccgcca cgcccagcac caccagcgcg cggagcagcc ggtgcagcgc gccggggtcc
    16081 gacccggtgc gctccgcgag ccgcgcgacc ggtacggcct cctccgcgag caggtccggc
    16141 acgccgagcc gtacggcggc gtagaggatc tgcgaggtgg cgtagccgaa ggccatccgg
    16201 gacaggttcg cctgccccgc gaggcctcgc ggtcggtcac tcatgggccg gctccttccg
    16261 gaggctctga cagacaaggg acaggcgtca cgcgacgccc gcctccaggc gcagccgcag
    16321 cggcaggcgg cgtacgccgt gcaggaacag gtcgggcgtc cactccaggc cggcggggtc
    16381 gaccgcgagg gcgatgtcgg ggaatcggcg caccagcgcc ccgatggcgg ccacggcctg
    16441 cagccgcgcc agcgccgcgc cgaggcagaa gtgcgcgccg tggccgaagc ccagatgccg
    16501 gttggggctg cgggcgatgt cgaagtcgtc cggccggggg aagaccgccg ggtcgcggtt
    16561 ggccgccagc agcaccggca cgaccacgtc cccgcggggg atgacggtcc cgccgatctc
    16621 gacgtcggcg aggacgtaca gcgggcggga gtgcccgacc gggccgttga accgcagcgc
    16681 ctcctcgacc atggagccga tcagctccgg gcgcgcccgc agccggtcca gctggcgggg
    16741 gtgccgcagc agctccagca cgccgttccc gatcaggttg acggtcgtct cgtccccggc
    16801 gagcagcagc tggaacacgc tggagaccag ctccgcgcgg ctgatcccgc ccgtccgctc
    16861 ggcctcggcg agccggctca gcaggtcgtc ccccgggtgc gcccgccgct cgtcgatcct
    16921 ctcgttggcg tacgcggcga actccaggcc ggcccggcgg atccggcccg cgtccccgct
    16981 gcccacgatc tcgtcgctcc acccgcgcag ccgggcgcgg tcctcggggg gcaggccgag
    17041 caggtcggcg acgaccagga ccggcagcgg cagcgccagc tcccggatga ggtcggcctc
    17101 gccgcccgcc gccgccatgc cgtccaggag ctcgcccgcg acccggtgga cgcgccgctc
    17161 cagcgcggcc accgtacggg cgccgaaggc cggcgccatc agcctgcgga tgcgggtgtg
    17221 gtcgggcgga tcgaggtgga agacgttgcg ccgcagcatg gccagcggat cgcgcatctc
    17281 ggccctgcgg tgcggcgcgg cgagctcggg cggcagccgg tcgagctgac ggccgacgtc
    17341 cgggtcgagc agcgcgcgct gcacgtcggc gtaccgggtc aggtaccaca gcacccggcc
    17401 gctcccgggg ttcacgtacc ggtagacggg cgcctgctcg cgcatccggt ggaacagcgg
    17461 atgggggtcc ggccggtgcc gcgccgccgc cgggtcgaac agctgcgcgg ccgggccgga
    17521 cggctgcccg ggttcggtca cggtcacgac cctctcctca cgcggactca ccggcgttcc
    17581 gggacacggg ctgcccccgg cccccgcgcc ggcgtcagcg gtttccggag gcacgcgcgt
    17641 tctggacgtc gagggcgaag aaccgtctga cggcgtgtcc cagctcctgc gggccggtga
    17701 agccgcgccg ggccatctcc acctcggccg acgtcccctt cccgtgccag tggcgcagga
    17761 agagcttcgc gcagatctcc ggtggcggga cggcgatccg gccacgggtc cgctccgccg
    17821 cctcgtcggc gcgggcgacg atctccgacc actcctgcca gaggcccgac cgccggaccc
    17881 gttccagcac gaccggccgc cagtcctccg actgccagac cggccagacc cgcaccatga
    17941 ccagccgcag ctgttctccg atggggaggg cggcgcgctc ggtctccgtg agccacggcg
    18001 cgagcacggg cggcaagggc tcggcttcgg cgaccccgag ccgggcgcgc acgtacgcct
    18061 ccaggtcgag gccccggccg gcggcgaagc cggtcagcag gcccgtcagc gtctcctcgt
    18121 gcaggcgggg gtagtcgtcg ccgaacagcc gccccgcggt cacgacgtcg aggtcggtca
    18181 tccaccggcc cggcgcgtac tcgcgcctcg accgccactt gagcgcctcg tagtgggtga
    18241 tcccggtcag cgccgtgtcg gccgcccacg cctcgggctc cccaccgggc ctctcgccgg
    18301 gccctccggc gcggcgctcg ccggccgcct gcagcgcggc cagcgcgtcc agcgcgtcca
    18361 gccgtttgac gtcccactcc cctgtgccga tcagccgccg cagcgtctcc aggcaggcgc
    18421 ggtcgtcgcc gtccaccgcc gcgccgagtt cctgccaggt gcggtgcgcg aacggcatcg
    18481 ccttggccgc gcggacgatg cgctccccgg cctccgccgg gatccggccc gtcctcgccc
    18541 cctcccggca gccgtaccgg aggttgacca gcgcgaccgt cccggccggg tagccgaggt
    18601 cggcggggcc gtgcagcacc gcgacctcgt cgtcgccgtc gacctcgccc gtcgtgtaca
    18661 tgtcgaacac ggtcccggcg ccggtcatgc cgtacgggct cagctcggcc gcgcgcaacg
    18721 cgcccatgct ggccgcgccg acgacgttca cgccctcggc gatcagccag aggatctcct
    18781 tgtggcccac cgccagcttc tcgcggtagt agccgtcgat gatgacggcg gtgtcgtccg
    18841 ggctccaggt ctcgctgagc aggtcgcccc gggcgacggg cggccgcacc cgcgcgtgcg
    18901 gcacgacgcc gcggacctcg tcgggggaga tcgtcggacc ggcgtagacg accacgttcg
    18961 gcgagctcat cgacgacccc cgctcatcgg aacaccctcg ctcatcagaa gacctccggg
    19021 cacacgcggc tccccggtgc cagcaccctg acgaccggca cgccgaggtc ctcccgcgtc
    19081 aggtcgacga cgagaggcgc gtgcgagaag gcgaccgtgg cgcgcttcac cacgtcgtcc
    19141 aggtcgtcga ccaggctctc gtgcgcgtgc agcggcgtga tcggcgcgcc gggctcctgc
    19201 ggcggctccg gtcgccgcgg cgcgccctgg ccgtcgtgga cgttcgcgtg caggtcgtcg
    19261 cgcgatcccg cgatgtagcc cagcctcgcc tgcgcggcct cggtgacggc gcggctgagc
    19321 gcgatctccg agctgaggtg gcagccgaag ccgaggaacg gcggcggata gtcgtcgcag
    19381 gtgatccggg cgaggaagca cggcagcccg gtcggcgagg ccagcgacct gacctccatg
    19441 cggacgcggg cccgttccat cgtcacgcac aggtcgtcga cgaccggcga gccgagcgag
    19501 cgcgggtcga cccgggtccc ccggtcgccg ccggtcatga aggcggtgac ggcgtcccgc
    19561 tcgatcacct cgtacaacgc gtgcagcacg ccctccgtca gcgtgttccc gctggccagg
    19621 ccgttggtcg aggagaagaa caccggcggg tgccagcccg tcctgcggac gagggtgaac
    19681 tgcgccagtt ccatggggac gagcgtcggc gagccgtcgg cgagcgatcg ggcggcgacc
    19741 cagtccaccg gcagcccgtc gtgcagcagg ctcggcgcgc agcgcggaag ggcgcccacg
    19801 tcgtagccca gttccccggc cagctcacgg gcggacgcgg tcgtgaccgg ccgcatgggc
    19861 tgctcggcgt gccagagctc gacggactcc atcatggccg acagcttcgc caggtccgcc
    19921 gtgacgccct tgccctggga gacggcgagg gtccgcgcgg caggcctgat cgcctggtac
    19981 gtcgggatgc cgagggtgtc gagccgggtg atgtccgcga cccgggtgac cccggcccgg
    20041 cgcgcggcgc ggccggccat ctccagggtg gcggcggggt ctcgggcccg gtccgtcccc
    20101 ggcagccgga ccttcgtctc gtcggagagg gagaggagcc aagagtggga ggaggtttct
    20161 gtccgcatcg tccccttgcc cgggtcgagg tgaggcgccc tgtcaggccg gccgtgtcag
    20221 gtgtcgggtc gtcagatgtt gcgtgcgcgg ttgatcaggg cgcggccgcc cacggtgtag
    20281 ccgacgaccg ccatgaccgc cagcacgagc aggtccaccc aggcctcgcc gaccccgaag
    20341 accgcggcgt cccgcatgcc gttgatcgcg tacgtcagcg ggttgaccac ggagatccac
    20401 tgcagcaccg tcggcatgct ctcggtggtg tacatcgacg gggcgctgaa gacgaggacg
    20461 ggcatcgaca cgttcgacag caccatgaag gcctggtagt ccgtgatcgt gatcgccgcc
    20521 gccaggtaga gcccgttgag cgccagggcc gacagcacga gcgccgacag cagccccacc
    20581 cagttctccg ggccgaacgg caggtcgaag atgagcgccg ccacgccgag gcccagcagg
    20641 gtctgcccca gcaccagcga gacgccggcg atcatcttgc cgagcaggaa gcgcgacctg
    20701 cgcatggggt acgaccacag ctgggtcgcc accccgctca tctcctcctg gaacacggcc
    20761 atggcggacg tcgccgccgc gctcacgacc gacatcgcca gcgtcatggg gagcaggaag
    20821 accgcgaacc cgacgctgac gcccttgtag tcgacgaccc tgacgaggtt actcagcgag
    20881 gtgttcacca gcaggaggta gaccagcatc ggcgtcaggc cgaggatcag gtagacccgg
    20941 ttgcgggcga gcagcgcgta ctcccggtag agcaccgcga gcaggtccgt cgccctcgcc
    21001 gtgggggcgg ggggcgcggc gtggaagtgc agcccggcgg ccatcgtcag ccctcgttcc
    21061 cggtcatccg gaggaagacc tcctcaagcg agtccacggc ggtcgacacc ccggtgatcg
    21121 cgacggcgtg gtcctggcag tagcgggaca gctccggcag caggtcgcgt gccttcgcgt
    21181 cgtcgatgcg cacctcgttg tcctcggcct tggccctgag cccggccgac tccgcccagg
    21241 cggccaccag gccgcccgac gccgggtcct cgacggtcac cagcaggtgg gtgctgccga
    21301 actcctccac gagttcgcgc ggcttggcga agcgcaccac ccgcccgcgg tcgacgacca
    21361 gcacgcgctg gctgttgcgc tccagctcgt cgatgtggtg gctggtccac agcaccgtca
    21421 cgccgtgctc ctcgcgcagc caggtcacga accgctcgac ctgacgccgc cccgcgacgt
    21481 ccaggcccgc ggagggctcg tcgaggatga gcagccgcgg gatggtgagc agcgcccgca
    21541 ccagttgcag ccgctgccgc tgaccacccg acatctggaa caccaggcgc tgcatcgagc
    21601 cggtgacgcc gaggaagtcc gccacctcga acgcccacgg ccgcacgtcg cgccaccgca
    21661 gcccgcggaa ccgggcggcg atccgcaggt tgtccagcgc cggcagcatc atgtcgaacg
    21721 gaccgctctg gtgcatcgcg ccgatgccgc tcttggcgag gacgggctga cgcaccggat
    21781 cggcgtcgaa gacccggatc tcaccggagg tcggagtggt gacgccgcag atcatcttga
    21841 tcagggtggt cttgccggcg ccgttggggc ccaggagccc gatggtctcc ccctgggcga
    21901 tctcgaagga gacgtcgtcc acggccggtc tctcgctgcc ccgatattgt ttggtcagcc
    21961 ccacggccgt cacgacgtct ctcaacacag cctgcccttc acttcgccct cccgctgccc
    22021 agcgatgtga gtcgccctcc gatcgtcccc cggcctgctc ggaacgcgtc gctggtcgag
    22081 tatgagccgg ggacgagcag gtgacacaac cccacaaacg tgggctaccg gcgtcgcccg
    22141 gagggccata accacggcca tggcccggcc ataccgatcg ttaagcgcgc ctttctaggg
    22201 tcgccgcaga ggggggcctc accaggtcac acaatcgagc gatccgaacc gggactgcac
    22261 atggaccttg tttccgacgg cctgatcaat gatcgcgacc gatggctgat cgtcatgctg
    22321 gccaggggct acacgacgac gaagatcgcc cacgagatgc acctcagccg gtacaccgtg
    22381 gcggagcgga tcagcaagct gctcctccag ttcgcctgca gcaaccgcag ccagctcgtg
    22441 gcctacttct acgcgcaccg gctcctgcac gtcggcatct ggccgcccag cgtctccgac
    22501 gccctcgggt aagccggccc tacggttcac gcggggtcca cgcgcgggcg ggagcgggcg
    22561 gcccggcgtg gtcccggccg tctctgaaac tttcgtcccg cgcggcgggc cgtgccagct
    22621 caccgcccgt ttccgctgcc ccggcggcct tccgccttgt ctcccgcccg ggcctttggc
    22681 cagcgtgagg ccctggccgc gacggcgact cccggtaatc ccccgccgtc aggccgccag
    22741 gatcccaggg attcggaagg aaacccgtgc tcagaaaaac gcttcccgcc gccctcacgg
    22801 tggcgatggc cctggccgcc ggcgcggccg gagcggctcc ggccgccctc gccgccgcca
    22861 ccggcccggc ggtcaccgtg gacgtgaccg cggggcggca cgccatcagc ccgtacgtct
    22921 acggcatgaa cttcgccgac gagacgctgg ccaaggaact gcgcctgccc gtacggcgct
    22981 ggggcggcaa cgcgaccacc cgctacaact acctgtacga caccagcaac cgggcctccg
    23041 actggttctt cgagaacatc gcggaggaca acaccaaccc gtccgcgctc cccgacggct
    23101 ccagcgtcga caagttcgtg gagcaggacc ggcgcaccgg caccgacacg atcctcacca
    23161 tgccgctgat cggctgggcg ccgaagggcc gcgacgcctc ctgcggcttc tccgtcgcca
    23221 agtacggccc gcagcagcag accgaccagt ggcggcccga ctgcggcaac ggcgtgaagc
    23281 cggacggcac gaagatcacc ggcaacgacc cccacgacac gagcgtggag gccggggcgt
    23341 cgtacgtgaa ggactggatc gcccacctca ccggcaagta cggcacggcg gcgagcggcg
    23401 gggtgaagtt ctacagcctc gacaacgagc ccgacatctg gcacggcacg caccgcgacg
    23461 tccaccccga gggcgcgagc tcggtcgagc tgcgtgacaa gggatacctc atcggcgccg
    23521 cgatcaagac cgccgacccc ggcgccaaga cgctcgggcc ggtcggctgg ggctggtcct
    23581 cgtgggacta ctcgggcctc gaccaggagg tctgcggccg gaccaactgc tggtcgaacc
    23641 cgcccgacaa ggcggcccgc gacggcctgc ccttcacgac ctggtatctg cggcagatga
    23701 agaagtacga ggacacgaac cacctgcgcg tcctcgacta cttcgacgag cacttctacc
    23761 cccaggcctc gggtgtcgcg ttcgggagcg gcggcgaccc tgcgaccgac gcgctgcggc
    23821 tgcgttccac ccgggccctg tgggacccgt cgtacaccga cgagagctgg atcaacaccc
    23881 aggtccgcct catcccccgg atgaaggagc tggtcgccgc cgagtatccg ggcaccaaga
    23941 ccgcgatcac cgagtacaac tggggcgccc tcgaccacat caacggcgcg ctggcgcagg
    24001 ccgacgtgct cggcatcttc ggccgtgagg gggtcgacct ggccagcctg tggggcccgc
    24061 cgaccgcctc ccagcccggc gcgtacgcct tccggatgta cctcaactac gacggcaagg
    24121 gcggccgctt cggcgagacc gcggtcagct ccgtcagcgc cgaccaggac aagctcgcgg
    24181 tgtacgccgc cgagcgcgcc tccgacaagg ccctcaccct cgtcgtggtg aacaagaccg
    24241 gcgacgccct gaccagcgac atcgcgctca agggccgcac cggcgccgcg accgcgcagg
    24301 tctaccggta cggcgcggcc gacacctcgg ccatcaggag ggacgccgac gtccaggtgg
    24361 gcgcgagcgg cttcaccggc acgttcccgg cgaactcgat cagtacgatc gtcgtcccgg
    24421 cggggaccgt gacgtccccc agcccctcgc ccagcgcctc tccgtcgccg agcgcgtctc
    24481 cctcgccgag cgtctccccg tcgcccagcg tgtcgccctc gcgcagcccc agcccctccc
    24541 ccagcgcctc cccgacgcgg tcgccgtcgc cctcgccgtc gcccagcggg actccgacgc
    24601 cgcccggctc ctgctcggtg acgtacacca tcacgaacca gtggcccggc gggttccagg
    24661 ccgatgtgcg gatcgtcaac cgcggcgcct ccgccgtgaa gggctggcag ctcggctgga
    24721 cgttcggcaa cgggcagacc gtcaaccagc tgtgggacgg ctcgtacacc cagagcggcg
    24781 cgaaggtgac ggtgaccaac gcgagctaca acgcctcgat cgcggccaac ggaggcagcg
    24841 tgagcttcgg cttcatcggc ggctggaacg gctccaacac cgcacccaag cagttcaccc
    24901 tgaacggcgc ctcctgcggc gcctgacgtg aggacacgga gggcggcgcg gtcccgcacc
    24961 gcccgccctc cggccccagc ctggctcccg tccggcgcga tcgccgcgcg acgtgagcgg
    25021 tcatggaaag atcaccgcaa tggacgatga gatcggcttc ctcgagggtc cgttcgacag
    25081 tgacgaggcc gccgacgcgg tggcggagat cgaggttagc gacggccggt cggctcgtct
    25141 ccgcgctcaa cgagacgccg gtctggaccg agtggtggcg tccgtccggc tgcaggagtt
    25201 cctcgtcttc ggcacgctcg cgacgggccc gtacgcggaa caggtctccc ggggccgcct
    25261 caccgcggag gcgtggatcg acttcgggca cccgcacctg ctccccgacg aggacgtcga
    25321 gcgggaggtc gccgccgatc tgcaccgggc cctgtcggcc gcgggccgct acctcggcct
    25381 cgcctccctc ccgccactac ccgcctgacc tcgcccgatc aacggtacgt gtagcagtag
    25441 ttcgacttgc ccttgaaccg gtggaaggcc ttcgggtcgt ggaagcgcca tcggcagccc
    25501 gcgtcgcgct ggctctggga gaggtacatg gtgtcgccct tccgcttgac gcagtacgca
    25561 ccgggcgtgg gcgactcccg gtactcgacc cactcccagc cgaggctcac gcagtactcg
    25621 gtgaagtgtc cgccgcccag ctccacgagc cgcagggccg acgcgggcga cggcttcggc
    25681 gacttcgagg ccggaggatc cgcggggacc ggtgtggccg tcttcgagcg gcggacggtc
    25741 ggccgtgcgg tgatcgtcct cgtcggggcc gtccgggtga cgacgggccc ggccgtcggc
    25801 cggctcaccc gtggccgggg tgaggaggcg ggcgaggcgg accgcgaggc gggggtgcgc
    25861 gacggagtcc cggacggaga cgcgcctccg ccggccccgg ctgaggcggc ggccggggcg
    25921 gtgccggccg ccgccgcccg ctccgtcagg gagggcccgc ttcccgcgga cggccggcgc
    25981 agcgagggca gcagcgcgac ggcggcgacc agcgcggcca ccacgaccac ggcggcgacg
    26041 acggtcccga cgacccgccc gcgccgactg cggcccggcg cctcgaccgg cccggacgcg
    26101 gagggcccgg ggggcatggt ggctggggtg atcgcggccg gagtgagcgc gaccgggatg
    26161 atcggggccg gggtgggcgc ggccggggcg tcgtggcggg ggcgcacgag gcggtcgagg
    26221 atctcccgtg cggccgggcg ccgtccgggg tccttggcga ggcaggctgt gagcaggtcg
    26281 cgcagcggcg cctcgacgcc gtccaggtcg ggttcgtggt tgaggatccg gttgatgatg
    26341 gcggggatcg cgtcggcgcc gaacggcgcg cggccggtgg cggcgaacac catcgtggac
    26401 gcccaggcga acacgtccag ggcgaaaccg agctcgcccg ccgtgaactg ctcgggcgcc
    26461 atgtaggcgg gggtgccgac gacttggctg gtcacggtgc ccgcgccgac gagggcgcgg
    26521 gcgatcccga agtctatgac ccgcggcccg tccggtccga tcagcacgtt gtgcggcttg
    26581 aagtcccgat ggaccacccc ggcgtcgtgc agggcgacca gcgccgtggc cgtggcgatg
    26641 gcgagccgtt cgagcgcgcc gcccgacatc ggcccgtgcg cggccaccac ctggctcagc
    26701 gcgtgcccct ggacgtactc gctcacgatg tacggccggc cgccgtccac gccggactcc
    26761 agcacctggg ccgtgcagaa ccgggcgacc ctgcgggcga cctccgtctc gcgtacgaag
    26821 gcgtcgtggg ccgcagcgtc tcccccgagt cgcgcgtgga agagcttgac cgcgacgagg
    26881 ccgccggact cgccctcgcc gaggtagacg acgccctgcc ctccctcgcc gatcctgccg
    26941 gtgatgcggt aggagcccag gcgaccgggg tcgccgggct ccagcggctg cggcatgact
    27001 ctccgtcggg tcgggggcac gtacggcgct cccattatcc cgccgaagat cggcggcagg
    27061 gccgggttcg ccggaccgcg gccgcaccga cgcgccgagg gccgccgaag gcgtgcgccg
    27121 ggcacccccg cgagtggcgg ggatgcccgg cgtgctcctc ctggtcagga gcgcgtcatc
    27181 ggatttcgcc ggtcaggacg cgccgcaggt caggctgggc gtctcggcgc tgccgctgcc
    27241 ggtgaaaccg aaggtggtgg tgccgcccgc ggcgaccgtg ccgttgtagg actcgttgcg
    27301 gacggtgacg gccgagccgg agccagaccg gacgccgttc cacagctggg tgatggacgc
    27361 ggagccggac cagttccagc tcaccgtcca gcccctgatc gccgaaccgc cggcgctcac
    27421 cgtgacctcc gactggaatc cgccgggcca ggagttcacc gtccgcatcg tcgcgctgca
    27481 tccgcccggc tccaccgtgg gcgactccga cgggctgggc gaggggctgt cggagggagt
    27541 cgggctgggg ctgtccgacg gggtcgcgct cgggctgtcg gacggcgtcg cgctggggct
    27601 caccggcggc gtggggctgg gcgaggtgct ggggacggcg gcgttgaggg cgtcgaggac
    27661 cgaggtgtag gcggccttct tgttgccgtt gccgtcgaac agcagcgggg tgtcacccga
    27721 ccgccacgag tcgctgtcac gcacgcccca cacggtgatg ccgttgcacc gcggcaccgc
    27781 gaggcagtcg ttgaccacgt tggcataggt ctgcgcggac gcgccctgga tgtccagctc
    27841 ggtgatctgc acgtccaccc cgagcgcggc gaagctggac agcgtggtgc ggtagttgct
    27901 gttgtacggg ctgccgctgt tgaagtgcga ctggaagccg acgcagtcga tcggcacgcc
    27961 gcgctgcttg aagtccttga ccatgttgta gacgccctgc gtcttggccc aggtccagtt
    28021 gtcggtgttg tagtcgttgt agcagagctt ggcgtcggga tcggcggccc gcgcggtgcg
    28081 gaaggccacc tcgatccagt cgttgccggt gcgctggagg ttggagtcgc gccggccgcc
    28141 gttgctgtcg tcgaacgcct cgttgacgac gtcccaggcg tagatcttgc ccttgtagtg
    28201 ggacatgacg ccgttgatgt ggtcgatcat cgcctggcgc aggctgctgc ccgacagcga
    28261 ctgcatccag cccggctgct gctggtgcca ggccagcgtg tgaccacgaa cccgcttgcc
    28321 gttctgcacg gcccagttgt agatccggtc ggcgttggtg aaggtgaact gaccgcggtt
    28381 gggctcggtc gcgtcgatct tcatctcgtt ctcggccgtg atcatgttga actcacggtt
    28441 cgcgatggtc gtgtactgcg agtcgccgag cttgctcgcg ctgatcgcgg tgccgaagta
    28501 gcggccgctg cgggccgccg cctcgccgag tgtcgaggcg ggcggaccgg ccgacggact
    28561 gaccgacggg ctgggcgagg ggctgttcgg cggcgtgggc gacggggtgg gtgacggcga
    28621 gctcggcgtc gtgctgttga ggccgaggaa gttgatggcg taggcgatct ggccgttgag
    28681 gggcagcgag tggccctggc cggagacgct gacgccctcg acgggcggct gggtgccgtt
    28741 accgccgtac cgggtgcggg tccagcccga cgacggggtg tcggtggcgg ccggcgtctg
    28801 gctcacgccg ttgaggttgg tccactgctt gatctcttcg ccgaagttgt tgtagtgcag
    28861 cgtgctgtcg gtggtgccgt gccacagctg catgcggggg taggagccgg tgtatccgga
    28921 gtacatcgag cgggccaggt ctccccactg ctgggcggtc ttgctgacct gcccgttggc
    28981 gcactgactg ttccaggtgg agccgtcggt cgtcgcgaag cagcccgccg ggacgcccat
    29041 gaacgccgag cccgccttga acacgtccgg atactcggcg gcgagcacgt tcgtcatcat
    29101 cgcgccggag gagacgccgc tgacgtagat ccggccgggg tccacgttgt agcgcgacct
    29161 ggcgtagtcg accatcgaca tgatgcccac ggggtcgctg ccgccgcccc gcctgagcgc
    29221 ctggggcgaa tacacgtcga agcactgccc gctgcgggtg gcctcgggga acacgatgat
    29281 gtatccgtac tggtcggccg cggtgacgta gtcccggaag tacccgctgt acagcgcgga
    29341 cgcggttccc gtgcagtagt ggacggcgac cagcagcgcc ggccgggagg ccacccggtc
    29401 cggcacgtag atgtacatgt tgaggttgct cgggttgttc ccgaagctcg tcacccgggt
    29461 cagcgaggcc gcggcggccg gctgggcgac cagtaacgcg gccagcgcga ccacgggcat
    29521 cagcatggcc gccagcacgg ccacgatgcg tcgtctcacg tgagagttcc ttcctccggt
    29581 cgcaccggcc cggtgccgcg ccggcgacac ccgggatcgg gctccccgca ctgctccgag
    29641 atcgcgggac atcgggccac gcctccaccg gatcctgtgc catttaatgt ttcagaagac
    29701 tgcctaaaac tttccgacgt cacaaccggc ggccggttcg taccgaagcc aaccgaaaga
    29761 gccaaagctc acgagacggc caggccttcc aggaggatgg gaatctcgga aactttcaag
    29821 gatgtgtcga aatattccga gtacgttcgg cttttcgaca ccacctgcgg gaggagcgcc
    29881 cggacccggc tgttgaccac actgtcgcgg acccgtgaca atgtgtgcgt cccgggcccg
    29941 ctgggtgccg gcacgccgac agggccggga cggtgttcgg ccacgacgcg atcggcgccg
    30001 cgtcctcggg aaagggacca cgcgcgtgcg gctgccccgg cgcatcccgg ccgcgagggg
    30061 aaggcgggca ctcgcgggag ccctgctcgc cgtcgcggcc gtcgcgtgcg gtgggagcgc
    30121 gcctccgtcg cgcggcagcg cgtctccggc gaccgccgcc ggggcggt
//
