LOCUS       NZ_VYTZ01000003        21068 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold3, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000003
VERSION     NZ_VYTZ01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 692686)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 692686)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 286939
            Orig. end                         :: 308007
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21068
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /region_number="2"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /tool="antismash"
     cand_cluster    1..21068
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /kind="single"
                     /product="terpene-precursor"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21068
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11068](-)"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11068)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            248..1609
                     /gene="allB"
                     /locus_tag="F5972_RS09355"
                     /old_locus_tag="F5972_09355"
     CDS             248..1609
                     /EC_number="3.5.2.5"
                     /GO_function="GO:0004038 - allantoinase activity [Evidence
                     IEA]"
                     /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]"
                     /GO_function="GO:0050897 - cobalt ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="allB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132825.1"
                     /locus_tag="F5972_RS09355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09355"
                     /product="allantoinase AllB"
                     /protein_id="WP_404803045.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 2.3e-26, bitscore:
                     88.2, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGSLHDHAGEEEVSPGGGRRCDLVVRSRRVVTPKGERALAVAVRG
                     GLIEALLPYDDPSGAAEDVDLGDLPLLPGLVDSHVHVNEPGRTHWEGFATATAAAAAGG
                     VTTIVDMPLNSLPPTLDVASLEVKRKAAEGRCHVDVGFWGGAVPGNLPDLRPLHEAGVM
                     GVKCFLSPSGVEEFPELDHDGLRAALAEVAGFGGLLIAHAEDPALLTEPGGPAYDDFLR
                     SRPQEAERRAVERVIALAAETGARAHIVHVSAAACLGPLREARAAGVRVSAETCPHYLT
                     LAAEQVTGPAYKCCPPIREAANRDALWEALAEGVLMGIVSDHSPSTPDLKVPDFAEAWG
                     GISSLQVGLPAVWTAARARGYGLTDVVRWMAEGPARLAGLPYKGAIRPGNDADLVAFDP
                     DAEFTVDVAALHHRNPVSPYHGRRLSGVVRTTWLRGAPVDLAAPAGRLLTRGAR"
     gene            1606..2679
                     /gene="alc"
                     /locus_tag="F5972_RS09360"
                     /old_locus_tag="F5972_09360"
     CDS             1606..2679
                     /EC_number="3.5.3.4"
                     /GO_function="GO:0004037 - allantoicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0000256 - allantoin catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="alc"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541667.1"
                     /locus_tag="F5972_RS09360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09360"
                     /product="allantoicase"
                     /protein_id="WP_150933019.1"
                     /transl_table=11
                     /translation="MNAFTRLPDLALRTYGGSVVAANDESFAEREALIRPGPAEFRPHT
                     FGAKGQVYDGWETRRRREAGHDWAIVRLGMPGVIRGVVVDTAWFRGNYPPYASVEACAA
                     EGHPAPEELDGWVEIVPKSPLGGDAAHEFAVTDPRRFTHVRLNIFPDGGVARLRVHGRV
                     VPDPAFLRGLTVDLAALENGGLVTACSDEFYSSPNNVLAPGLARNQAEGWETARRRDGG
                     NDWLVVALAGPGRIAVAEIDTTNLKFNAPGWASLMGIDTGHAARTPPGLDTSQAPLDTS
                     QAPLDDGRALPPEDDAGRAPLPDDAAWFPLLPKTRLQPDTRHRFRLDDDRRVTHVRLDI
                     FPDGGLARLRLPGTLIP"
     gene            complement(3153..5165)
                     /gene="pknB"
                     /locus_tag="F5972_RS09365"
                     /old_locus_tag="F5972_09365"
     CDS             complement(3153..5165)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="pknB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889483.1"
                     /locus_tag="F5972_RS09365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09365"
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="WP_150933020.1"
                     /sec_met_domain="Pkinase (E-value: 3.4e-54, bitscore:
                     179.2, seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 5e-08, bitscore: 28.5,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDTTLTDPLVGQLLDGRYRVESRIARGGMASVYLALDVRLDRTVA
                     VKVMHRSLAEDPQFVQRFIGEAKSVASLSHPNIVQVFDQGTDGANVYLSMEYVPGRTLR
                     DILRQRGRLPAREALEMVIPVLAALGAAHQAGLIHRDVKPENVLLADDGRVKVVDFGLA
                     RAIEATNQTKTGMMIGTIGYMSPEQVTTGLADARSDVYAAGIMLFELLTGQPPYAGETP
                     MSIAYRHVHETVPAPSSVVPGIPPQIDALVTAATDKDPARRPADATAMLVAAVEIHRTL
                     PRTGHTGGHTRPGSAGDSMAGSPTGAHSGAGTGAHRAAVAPAGATPASGTAGHAQLGQT
                     MIQPRTDLLTGVMPGPAGAGGRRGTRRARPRPVWFLAVLALVMLAGVAFTGWWFSEGRY
                     TKVPDLVNKPLTVARQEAQSRGFEVQVLKPVFDDKVPKDVVLNTEPGPGAEAVKGAVLK
                     LIPSAGPETIPVPKVEGLSLADARAKIAEAGLTPGRVSRSASETIPRDQVIRTNPLVGK
                     RVRKGGAVNFVVSAGLLMPDVTQMMRDQAEKFLRDKGFNVQIDETADDAPPGTVIAQDP
                     SGGAETVAGATVHLTVSRGPDQGFHWPWETDPSQAAPDFVNVPDVRFKAVRDAVSELKA
                     AGFKVKVRELVGTQRVVGENPLGQQPQGATITIWH"
     gene            complement(5311..6099)
                     /locus_tag="F5972_RS09370"
                     /old_locus_tag="F5972_09370"
     CDS             complement(5311..6099)
                     /EC_number="2.8.1.10"
                     /GO_function="GO:1990107 - thiazole synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011291489.1"
                     /locus_tag="F5972_RS09370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09370"
                     /product="thiazole synthase"
                     /protein_id="WP_404803046.1"
                     /transl_table=11
                     /translation="MTGMTEQDASGDVFVLGGEKFASRLIMGTGGAPSLEVLDQALEAS
                     GTELTTVAMRRLDPAARGSVLDLLRSRDIKVLPNTAGCFTAGEAVLTARLAREALETNW
                     VKLEVIADERTLLPDPIETFDAAERLVADGFVVLPYIGDDPALARRLEDAGCAAVMPLG
                     APIGSGLGIRNPHSIELIAEAATVPVILDAGIGTASDAALAMELGCDAVLLASAVTRAH
                     RPGLMAAAMRQAVTAGRLARLAGRIPRRRYAKASSPVRSS"
     gene            complement(6107..6307)
                     /gene="thiS"
                     /locus_tag="F5972_RS09375"
                     /old_locus_tag="F5972_09375"
     CDS             complement(6107..6307)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889485.1"
                     /locus_tag="F5972_RS09375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09375"
                     /product="sulfur carrier protein ThiS"
                     /protein_id="WP_150933022.1"
                     /transl_table=11
                     /translation="MKVTINGGPAELPEGATVGDAVRTLTALTSGVAVAVNGEVVSRGA
                     WDSTRVEDGDGVEVLTAVQGG"
     gene            complement(6304..7440)
                     /gene="thiO"
                     /locus_tag="F5972_RS09380"
                     /old_locus_tag="F5972_09380"
     CDS             complement(6304..7440)
                     /EC_number="1.4.3.19"
                     /GO_function="GO:0016647 - oxidoreductase activity, acting
                     on the CH-NH group of donors, oxygen as acceptor [Evidence
                     IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene="thiO"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017573834.1"
                     /locus_tag="F5972_RS09380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09380"
                     /product="glycine oxidase ThiO"
                     /protein_id="WP_150933023.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 8.4e-08, bitscore:
                     27.1, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 3e-73, bitscore: 242.7,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTRPSGSEPGHDVVIVGGGVAGLAAAWRTARRGLSVAVVDPAP
                     GSGATHAAAGMLAPVSEVTYTEEPLLRLGLASLATWPAFRAELEDESGAELDYRTEGTL
                     EVARGTDDMAVLDDLAAFERTLGLRVERLTGRECRSFEPMLSPSVRGGLLARDDAWVDP
                     RRLVRALLTAFEKAGGTLVAERAAGIVLPGRGSPSVRLTSGGTVPAGRIVVAAGSWSAA
                     LLPGLPVRPVKGQILRLRGPRGFLTRCVRGLVHGSPAYLVPRGDGEIVLGATSEELGYD
                     ARVTAGGVYELLRDARELVPGLTELELAETAVGFRPGTPDNLPLIGPTGPPGVLAATGH
                     GRNGVLLAPVTAEAVAALLTGGAVPEAALSCDPGRFHS"
     regulatory      complement(7429..7540)
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(7604..7619)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: strong, score: 18.39"
                     /tool="antismash"
     gene            7712..8890
                     /locus_tag="F5972_RS09385"
                     /old_locus_tag="F5972_09385"
     CDS             7712..8890
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889487.1"
                     /locus_tag="F5972_RS09385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09385"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_191910036.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 4.7e-52, bitscore:
                     172.3, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHVVVVGAGLAGVRSIEALRSRGFTGRITLIGEEHHRPYDRPPL
                     SKAVLLGDADSTVVDSDLDAMDVRLCLGTAAKGLRDGVLETTEGELEYDGLVIATGATP
                     VRLRGEGHQHVLRTIDDALALRERLVPGARVAVVGAGWIGAEVATAAAKAGCAVTVVEA
                     GESPLAAAIGPAVGCHTIGWYARAGVELRLGAMVGTVDADGLTLMSGARVPADVVVSGV
                     GVRPSVHWLKGSAVRLDNGVLVDEHLRTSLPNVVAVGDCANWWSRRFGTRLRVEHWDTA
                     LQAPDTAAATLLGEEAVYDPVPYFWSEQFDHMLQFAGHPTPDDRMLLRGDPRADGKWAV
                     CWLTPEDRLAAVFTVDRPRDVVQGRRLVEGGRRLDPRRVADAAVPLRDCIMA"
     gene            8934..9311
                     /locus_tag="F5972_RS09390"
                     /old_locus_tag="F5972_09390"
     CDS             8934..9311
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020541673.1"
                     /locus_tag="F5972_RS09390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09390"
                     /product="Rv2175c family DNA-binding protein"
                     /protein_id="WP_150933024.1"
                     /transl_table=11
                     /translation="MTLTVAQIDRETDQLVGEWLPLPQAAEKLGLSIGRTKQLLKDKKL
                     VGARRSGGGQPQIPSVFVAHGDVLKGLPGTLTVLADAGYDEVESIRWLFTPDDSLPGSP
                     IDAIVKGRHTEVKRRAQALGF"
     gene            9340..9990
                     /gene="thiE"
                     /locus_tag="F5972_RS09395"
                     /old_locus_tag="F5972_09395"
     CDS             9340..9990
                     /EC_number="2.5.1.3"
                     /GO_function="GO:0004789 - thiamine-phosphate
                     diphosphorylase activity [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="thiE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1280: thiamine-phosphate pyrophosphorylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131594.1"
                     /locus_tag="F5972_RS09395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09395"
                     /product="thiamine phosphate synthase"
                     /protein_id="WP_150933025.1"
                     /transl_table=11
                     /translation="MNDTRRRLAQARLYLCTDGRRDRGDLEDFLDAVLAGGVDIVQLRE
                     KGLEAREELGLLEVFRAACDRHGALLAVNDRADVAYAARPDILHLGQDDLPVPVAREIL
                     GSGVLVGRSTHSAAEASAAAVEPGVDYFCCGPVWPTPTKPGRPAPGPALLEHAASLGTD
                     RPWFGIGGIGPDNLDEVMAHGVRRAVVVRAVTEAEDPGAAAAALKARLSAVPL"
     gene            complement(10001..11068)
                     /locus_tag="F5972_RS09400"
                     /old_locus_tag="F5972_09400"
     CDS             complement(10001..11068)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131595.1"
                     /locus_tag="F5972_RS09400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09400"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_150933026.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3e-50, bitscore:
                     166.2, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTSAASLDHIRTEVDRVLREFLDRQRPHFEDPHLAVLLSAAEDF
                     LAGGKRLRPAFCHWGWRAAGGGDEPGLHFAAASLELLQASALIHDDVMDASDVRRGMPS
                     AHRRFERMHADAGWHGSARQFGEGSAVLLGNLLLVWSGEMWRGSGLDPRAIAAAQPLHD
                     YMLTELMCGQYLDLLEQAQGESTFDSALRVALYKSGKYSVEQPLRLGLVLAARARHPWI
                     DRLCVQYGQRVGIAFQLRDDILGVFGDPAETGKPAGDDLREGKRTVLIARALAGATPAQ
                     QDVVRTLLGDPGLDADGVASLRTLIEETGALTDCEDMIKRYLDEAMHALEQAPIEEDAR
                     AALAALAVAATSRRT"
     misc_feature    11148..11161
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.87"
                     /tool="antismash"
     gene            11235..12161
                     /gene="metF"
                     /locus_tag="F5972_RS09405"
                     /old_locus_tag="F5972_09405"
     CDS             11235..12161
                     /EC_number="1.5.1.20"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0004489 - methylenetetrahydrofolate
                     reductase (NAD(P)H) activity [Evidence IEA]"
                     /GO_process="GO:0009086 - methionine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="metF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131596.1"
                     /locus_tag="F5972_RS09405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09405"
                     /product="methylenetetrahydrofolate reductase [NAD(P)H]"
                     /protein_id="WP_150933027.1"
                     /transl_table=11
                     /translation="MALGLPSRLPDRVPTVRELLAAGERSFSFEFFPPKTDEGERQLWR
                     AIRELEALRPTFVSVTYGAGGSTRDRTVDIVERLAHETTLTPVAHFTAVDHSIRELRHL
                     VGRFADAGVRNILAVRGDPRGGNPLDEWVRHPEGVLYAEDLVRLIRQAGDFCVGVAAFP
                     YKHPRSATIESDTNYFVQKCRAGADYAITQMFFRAEDYLRLRDRVAAQGCDTPIIPGVM
                     PVTQMSTIARSEQLSGAPFPPEVAERFAAVADDPVAVRRLGIEHAAEMCQTLLDEGAPG
                     IHFITFNRSSATREVFKALHGVPAVAG"
     gene            complement(12171..12743)
                     /locus_tag="F5972_RS09410"
                     /old_locus_tag="F5972_09410"
     CDS             complement(12171..12743)
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131597.1"
                     /locus_tag="F5972_RS09410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09410"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_150933028.1"
                     /transl_table=11
                     /translation="MIRLRRVGPDTFRAVLDTVLEIYTDAMRPPSDQLAGRMAIMRNHA
                     AYPDFACVLAEDPQGPGIAGFAYGFHGGPGQWWHDVVRGGLQDRAGPVVADEWFGDALE
                     IAEIHVRPEYQGKGVGRRMIHALCEGRPERTAVLSTHDAPTAARHLYRDVGFADLMTRF
                     VFPGGYEEYVIAGVRLPLPGPAPFPKD"
     gene            complement(12786..13262)
                     /locus_tag="F5972_RS09415"
                     /old_locus_tag="F5972_09415"
     CDS             complement(12786..13262)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131598.1"
                     /locus_tag="F5972_RS09415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09415"
                     /product="YbaK/EbsC family protein"
                     /protein_id="WP_150933029.1"
                     /transl_table=11
                     /translation="MPEKLHPNVVRVEQALRDRQVTGEVVVLDDAAPTAATAAAQLGCE
                     IGAIANSLIFDADGAPLLVLTSGAHRVNTDLIARLVGAAKVRRATPEFVREHTGQPIGG
                     VAPVGHPAPVRTLVDTWLGKHEVVWAAAGHPHSVFPTSFDELVRITGGTPAEVG"
     misc_feature    complement(13305..13319)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.86"
                     /tool="antismash"
     gene            13387..14268
                     /locus_tag="F5972_RS09420"
                     /old_locus_tag="F5972_09420"
     CDS             13387..14268
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131599.1"
                     /locus_tag="F5972_RS09420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09420"
                     /product="L,D-transpeptidase family protein"
                     /protein_id="WP_225311304.1"
                     /transl_table=11
                     /translation="MMRGRRRPAVAMLAAVGAVTFATAGVAGPARAAAVPAGAVTYATA
                     GLTGVAPAGAARTLTAPAAGTRGALPGRAGYPPFEAPGKTLKLGAKGGAVKALQVRLKE
                     LGYVPGSADGRYGGATLTALWAFQKVQGITPTSTVAARTWRALENPRAPRVLVPRGKAG
                     RVEVDLTKQVMVLYRSGVPVLISHISSGSGVPYTEYAVWNGKRQVFSGSARTPTGDYKT
                     TWRARGWHRSYLGQLYNPIFFNGGIALHGALSVPLYPASHGCVRLPMNVAEILPGMLGK
                     GVPVHVRGAFRR"
     misc_feature    complement(14340..14353)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.27"
                     /tool="antismash"
     misc_feature    14379..14394
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 25.49"
                     /tool="antismash"
     misc_feature    complement(14380..14393)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 21.0"
                     /tool="antismash"
     gene            14659..15096
                     /locus_tag="F5972_RS09425"
                     /old_locus_tag="F5972_09425"
     CDS             14659..15096
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012889496.1"
                     /locus_tag="F5972_RS09425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09425"
                     /product="SAV_6107 family HEPN domain-containing protein"
                     /protein_id="WP_150933030.1"
                     /transl_table=11
                     /translation="MTEENGDQRTGPRLPQAVLARLADARACLADATVGTTPADRYVSA
                     HLAALRAAAGILAARPRPMDGRRRRLRSAWELLPEAEPKLADWAAYFAMSATKRAAVEA
                     GMVRAVTQNDADEIIAEADRFVGEVESILGLPGRPTLPMAG"
     gene            complement(15101..16345)
                     /locus_tag="F5972_RS09430"
                     /old_locus_tag="F5972_09430"
     CDS             complement(15101..16345)
                     /EC_number="3.5.3.6"
                     /GO_function="GO:0016990 - arginine deiminase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006527 - arginine catabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017541643.1"
                     /locus_tag="F5972_RS09430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09430"
                     /product="arginine deiminase"
                     /protein_id="WP_150933031.1"
                     /transl_table=11
                     /translation="MTFFVGSEVGRLRQVLVDIPELALKRLTPGNKDGLLFDDVLWVQR
                     ALEEHREWCEVLTARGVTVHHLGDLLREVIEVPDARKHILDGSVDEHWFGPLAADAIRN
                     TLDALDGAALAPYLTGGITKREIRELGCDPGSVVFHALGLDDFVLPPLPNHLFARDTSC
                     WVYGGVSINAMRKKARRRETLNYEAVYRWHPMFAPGYGDPSGGGFDVWYDGTRMAPATI
                     EGGDVLVLGDGVVLVGMSERTQPQAVEMLATNLFRAGAATRIVALDLPKTRAFMHLDTV
                     MTNVDVGVFTKYAGLGMLPSYTVEPGDTDKELKVVDHPPEDMHRAIARALGLDDIKVLT
                     PTQDVHAAEREQWDDGCNVLALEPGVVVAYERNTTTNNHLRRHGIEVIPIRGSELGRGR
                     GGPRCMSCPLERDPA"
     misc_feature    16336..16350
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 16.39"
                     /tool="antismash"
     gene            complement(16464..16958)
                     /locus_tag="F5972_RS09435"
                     /old_locus_tag="F5972_09435"
     CDS             complement(16464..16958)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017622275.1"
                     /locus_tag="F5972_RS09435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09435"
                     /product="transcriptional regulator"
                     /protein_id="WP_117408562.1"
                     /transl_table=11
                     /translation="MPSDYAKSLGARLRAIRTQQGLSLHGVEEKSRGRWKAVVVGSYER
                     GDRAVTVQKLAELADFYGVPVSELLPGGAAPSPLAPAPKLVIDLERLSQLPKDKAGPLA
                     RYAATIQSQRGDYNGKVLSIRQEDLRSLAVIYDKSPVELTEEFINWGVLDAEARRAVES
                     F"
     gene            17374..17931
                     /gene="pyrR"
                     /locus_tag="F5972_RS09440"
                     /old_locus_tag="F5972_09440"
     CDS             17374..17931
                     /EC_number="2.4.2.9"
                     /GO_process="GO:0009116 - nucleoside metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pyrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131602.1"
                     /locus_tag="F5972_RS09440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09440"
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="WP_150933032.1"
                     /transl_table=11
                     /translation="MSDAQNQARAVLEGPDIHRALTRIAHEILERTRGAESVVLLGIPT
                     RGATLAHRIAGRIAQFEGIKVPVGAIDITMYRDDLRLRPARPLGRTELPPDGVDGRTVV
                     LVDDVLFSGRTVRAALDALNDVGRPRAVQLATLVDRGHRELPIRADYVGKNLPTSKSEK
                     VKVFLQETDGRDAVVLIKGDDR"
     gene            17928..18863
                     /locus_tag="F5972_RS09445"
                     /old_locus_tag="F5972_09445"
     CDS             17928..18863
                     /EC_number="2.1.3.2"
                     /GO_function="GO:0004070 - aspartate carbamoyltransferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0016597 - amino acid binding [Evidence
                     IEA]"
                     /GO_process="GO:0006207 - 'de novo' pyrimidine nucleobase
                     biosynthetic process [Evidence IEA]"
                     /GO_process="GO:0006520 - amino acid metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1114: ornithine carbamoyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013131603.1"
                     /locus_tag="F5972_RS09445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09445"
                     /product="aspartate carbamoyltransferase catalytic subunit"
                     /protein_id="WP_150933033.1"
                     /transl_table=11
                     /translation="MKSHLLSTGDLSRDDALLILDTAEELARVSQRSIKKLPTLRGRTV
                     VNLFFEDSTRTRISFEAAAKRLSADVINFSAKGSSVSKGESLKDTALTLEAMGADAVVI
                     RHSASGAPHRLANWVRGSVVNAGDGTHEHPTQALLDAFSIRRRLGRLDGLKISIVGDVL
                     HSRVARSNVLLLHTLGAEVTLVAPPTLLPVAVESWPCQVSYDLDAVLPKSDVVMMLRVQ
                     LERMNAAYFPSAREYSRRYGLDRDRFARLHDDAIVMHPGPMNRGMEISAEVADSPRSTI
                     VEQVGNGVTVRMAVLYLLLGGSEPAIGGAE"
     gene            18890..20191
                     /locus_tag="F5972_RS09450"
                     /old_locus_tag="F5972_09450"
     CDS             18890..20191
                     /EC_number="3.5.2.3"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630797.1"
                     /locus_tag="F5972_RS09450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_09450"
                     /product="dihydroorotase"
                     /protein_id="WP_150933034.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 8.8e-17, bitscore:
                     56.6, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTILIRGARILGGAPRDILLRDGLVAEIGDLAGAGADQTVDATG
                     LVALPGLVDLHTHLREPGREDAETVETGTQAAARGGYTAVHAMANTSPVADTAGVVEQV
                     WRLGQESGHCDVQPVGAVTSGLEGRQLAELGAMADSAARVRVFSDDGRCVSDAVLMRRA
                     LEYVKAFDGVVAQHAQEPRLTEGAQLNEGEVSARLGLTGWPAVAEEAIIARDCLLAAHV
                     GSRLHVCHVSTAGSVEIIRWAKSKGWDVTAEVTPHHLLLTDSRAETSPLGPYNPIYKVN
                     PPLRTAEDVRALREALADGTIDCVATDHAPHPVEDKETEWAAAAMGMIGLETALPVVQE
                     AMVETGLLDWAGVADRMSARPARIGRLAGHGRPIEPGAPANVTLYDPSVRRPVDPTAMA
                     SKSRNTPYEGMTLPGRVVATFLRGRPTVLEGKLV"
     misc_feature    20597..20612
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 21.29"
                     /tool="antismash"
ORIGIN
        1 gccggtcacg gcgtgccggt cgtggccgtc tgcggccgcc gcacggtggg cgacgacgaa
       61 ctgaagaagg cggggatcga ggcggcgtac gcgctgaccg acatcgagcc cgacgtcgcg
      121 aggtgcgtgg ccgaggccgg gccgctgctc gaacggctgg cccgccggat cgcggccgag
      181 cacctcacca ggaggtagac gccggcgcgg gaccatgccg gctgacgccc ggatcgcgag
      241 aggagcggtg ggttctttgc acgatcacgc gggggaagag gaggtctcac ccggcggcgg
      301 ccggcggtgc gacctggtgg tgcggtcgcg gcgggtcgtg accccgaagg gggagcgggc
      361 gctcgccgtc gccgtgcgcg ggggcctgat cgaggccctg ctgccctacg acgacccgtc
      421 cggcgccgcc gaggacgtcg acctcggcga cctgccgctg ctgcccgggc tggtcgactc
      481 gcacgtgcac gtcaacgagc ccggccgcac ccactgggag ggcttcgcga ccgccaccgc
      541 cgcggcggcg gccgggggcg tcaccaccat cgtggacatg ccgctgaact cgctgccgcc
      601 gaccctggac gtcgcctcgc tggaggtcaa gcggaaggcc gccgagggtc ggtgtcacgt
      661 ggacgtcggc ttctggggcg gcgcggtccc gggaaacctg cccgacctgc gccccctgca
      721 cgaggccggg gtcatgggcg tcaagtgctt cctgtcgccg tccggggtcg aggagttccc
      781 cgagctcgac cacgacgggc ttcgggccgc gctcgcggag gtggcgggct tcggcggcct
      841 gctgatcgcc cacgccgagg acccggcgct gctgaccgag cccggcggcc cggcgtacga
      901 cgacttcctc aggtcgcgcc cgcaggaggc cgagcggcgg gccgtggagc gggtgatcgc
      961 gctggccgcc gagacgggcg ccagggcgca catcgtgcac gtgtcggccg ccgcctgcct
     1021 cgggccgctc cgcgaggcgc gggcggccgg ggtgcgcgtc agcgccgaga cctgccccca
     1081 ctacctgacc ctggcggccg agcaggtcac cggcccggcg tacaagtgct gcccgccgat
     1141 ccgggaggcg gccaaccgcg acgcgctgtg ggaggcgctc gccgaggggg tgctgatggg
     1201 gatcgtctcc gaccactccc cgtcgacgcc cgacctcaag gtccccgact tcgccgaagc
     1261 gtggggcggg atctcctccc tccaggtcgg cctgcccgcc gtgtggaccg ccgcccgcgc
     1321 ccgcgggtac ggcctgaccg acgtcgtccg ctggatggcc gagggtcccg cccgcctcgc
     1381 gggcctgccg tacaaggggg cgatcagacc gggcaacgac gccgacctgg tggccttcga
     1441 ccccgacgcc gagttcacgg tcgacgtggc ggcgctgcac caccgcaacc ccgtgtcgcc
     1501 ctaccacggg cggcgcctct ccggcgtcgt ccgcaccacc tggctgcgcg gcgcccccgt
     1561 cgacctcgcc gctccggccg gtcgccttct gacccgggga gcgcggtgaa cgccttcacc
     1621 cgcctgcccg acctcgccct ccgcacgtac ggcgggtcgg tcgtggcggc caacgacgag
     1681 tcgttcgccg agcgggaggc cctgatcagg cccggacccg ccgagttccg gccgcacacc
     1741 ttcggcgcga agggccaggt ctacgacggc tgggagacgc gccggcggcg cgaggcgggc
     1801 cacgactggg cgatcgtccg cctcggcatg ccgggagtca tccggggcgt cgtcgtcgac
     1861 accgcgtggt tccgcggcaa ctacccgccg tacgcctcgg tggaggcgtg cgcggcggag
     1921 ggccatccgg cgccggagga gctggacggc tgggtggaga tcgtgccgaa gagcccgctc
     1981 gggggcgacg cggcccacga gttcgcggtg accgatcccc gccggttcac gcacgtccgg
     2041 ctgaacatct tccccgacgg cggcgtcgcg cggctgcggg tgcacggccg ggtcgtgccc
     2101 gacccggcgt tcctgcgcgg gctgaccgtc gacctcgccg cactggagaa cggcgggctc
     2161 gtcaccgcct gctccgacga gttctactcc tcgccgaaca acgtcctcgc gcccgggctc
     2221 gcccgcaacc aggccgaggg ctgggagacg gcccggcggc gcgacggagg caacgactgg
     2281 ctcgtcgtcg ccctcgccgg gcccggccgg atcgccgtgg ccgagatcga caccaccaac
     2341 ctgaagttca acgcccccgg ctgggcctcc ctcatgggca tcgacaccgg ccacgccgca
     2401 cggacgccgc cgggcctgga caccagccag gcgcccctgg acaccagcca agcgcccctg
     2461 gacgacggcc gagcgctccc gccggaggac gacgccggtc gggcgcccct gccggacgac
     2521 gccgcctggt tcccgctgct gccgaagacc cggctccaac ccgacacccg ccaccgcttc
     2581 cgcctcgacg acgaccgccg cgtcacccac gtccgcctcg acatcttccc cgacggcggg
     2641 ctcgcccgcc tccgcctccc cggcaccctc atcccctgag cacctgaacc ggtggaatcg
     2701 ctgcgaaccg aggaccacac gaagtagggt gacaagacga tttcggaggg tagcgaaacg
     2761 agcacggttc gttctgctgc actgggacca ttactccccg ccgtcctccg ggactggcgg
     2821 ggctttttta tgtggggatc ctgccaggat cgccgacctg atcggtcagc ggagatcacg
     2881 cacgagcgag gtgacggcgg tgcgggtcta ccggggccgt cctgacccca actatcagcc
     2941 gttaccggca gcagccaacg atgctcaggc ggcgcggtgg acacacgacc gcagtgctgg
     3001 tcggggttca agcctctccg gatcaaaggc accaatcttc cctactgcca cttcctgaac
     3061 aaggacgatt gggcagcggt cactgaggac tggactgacc gcatctgagg agaggcggcg
     3121 cgcggagatt cgcagcggcg gtgaggtggg ggtcagtgcc agatcgtgat ggtggcgccc
     3181 tggggttgct ggccgagggg gttctcgccg acgacgcgct gggtgccgac cagctcacgg
     3241 accttgacct tgaagccggc cgccttcagt tcggacaccg cgtcccgcac cgccttgaac
     3301 cgcacgtcgg gcacgttcac gaagtcgggc gccgcctgcg agggatcggt ctcccacggc
     3361 cagtggaagc cctggtcagg gccgcgtgac acggtcaggt gcacggtcgc cccagccacc
     3421 gtctccgcgc cgcccgaggg gtcctgcgcg atcacggtgc ccggcggggc gtcgtcggcc
     3481 gtctcgtcga tctggacgtt gaagcccttg tcgcgcagga acttctccgc ctggtcgcgc
     3541 atcatctgcg tgacgtccgg catgagcagc ccggcgctga ccacgaagtt gaccgcgccg
     3601 cccttcctga cgcgcttgcc cacgagcggg ttcgtacgga tgacctggtc acgcgggatc
     3661 gtctcgctcg cgctccggct gacccggccg ggggtcagcc cggcctcggc gatcttcgcc
     3721 cgggcgtccg ccaggctgag gccctcgacc ttcggcaccg ggatggtctc cgggccggcc
     3781 gacgggatca gcttgagcac cgctcccttg accgcctccg cccccggccc cggctcggtg
     3841 ttcaggacga cgtccttggg gaccttgtcg tcgaacaccg gcttgaggac ctgcacctcg
     3901 aaaccacggc tctgcgcctc ctgccgcgcg accgtgaggg gcttgttcac caggtcgggc
     3961 accttcgtgt agcggccctc ggagaaccac cagcccgtga aggcgacacc cgcgagcatc
     4021 acgagggcca gcacggcgag aaaccagacc ggtcgtggcc gtgccctgcg ggtcccgcgg
     4081 cgccctcccg cccccgcagg gccgggcatg acgccggtca gcaggtccgt acgcggctgg
     4141 atcatcgtct ggccgagctg cgcgtgcccg gccgtgccgg acgcgggggt cgcgcccgcc
     4201 ggggccacgg ccgcgcggtg cgcccccgtg ccggcgccgc tgtgcgcgcc cgtgggagag
     4261 cccgccatgg agtcgcccgc ggagcccggg cgggtgtgcc cgccggtgtg cccggtcctc
     4321 ggcagcgtgc ggtggatctc gacggcggcg accagcatgg cggtcgcgtc cgccgggcgc
     4381 cgggcggggt ccttgtcggt ggcggccgtg acgagcgcgt cgatctgcgg cgggatgccg
     4441 ggcacgaccg aggacggcgc gggcacggtc tcgtgcacgt gccggtaggc gatcgacatc
     4501 ggcgtctcac cggcgtacgg cggctgcccg gtgagcagct cgaacagcat gatcccggcg
     4561 gcgtacacgt cgctgcgcgc gtcggcgagg ccggtcgtga cctgctcggg cgacatgtag
     4621 ccgatcgtgc cgatcatcat gccggtcttg gtctggttgg tggcctcgat cgcccgggcc
     4681 aggccgaagt ccacgacctt cacccggccg tcgtcggcga gcagcacgtt ctcgggcttg
     4741 acgtcccggt ggatcagccc cgcctggtgg gccgcgccga gggcggcgag caccgggatg
     4801 accatctcca gggcctcgcg agccgggagg cggccacgct ggcgcaggat gtcgcgcagc
     4861 gtcctgccgg ggacgtactc catcgacagg tagacgttcg ccccgtcggt gccctggtcg
     4921 aagacctgca cgatgttcgg gtgcgagaga ctcgccaccg acttggcctc gccgatgaac
     4981 cgctggacga actgcgggtc ctcggccagc gaacggtgca tcaccttgac ggcgaccgtg
     5041 cggtcgagcc ggacgtccag agccaggtag acggaggcca tgccgccccg ggcgatccgg
     5101 gactcgacgc ggtagcgccc gtcgagcagc tgccccacga gcggatcggt tagcgtcgtg
     5161 tccacccgcc cgagtttacg ggtcatttgc cgtcgggcgt gttcccgaac cccaaaccga
     5221 gacctggccg gctccctttc gcgcgacccg gaaagccgtc cctcgtccga aaaccggcct
     5281 tacccggcgc cggatcgaga aaggcgccgg tcaggaggag cggacggggg aggacgcctt
     5341 ggcgtagcgg cggcggggga tgcgcccggc caggcgggcg agccgtccgg ccgtgaccgc
     5401 ctgccgcatg gcggcggcca tgaggccggg ccggtgcgcc cgcgtcacgg cgctggcgag
     5461 cagcacggcg tcgcagccca gctccatcgc gagcgccgcg tcgctggccg tgccgatccc
     5521 cgcgtccaga atgaccggca ccgtggccgc ctcggcgatc aactcgatgc tgtgcgggtt
     5581 gcggatgccg aggcccgagc cgatcggggc gccgagcggc atcaccgccg cgcacccggc
     5641 gtcctccagc cggcgcgcca gcgcggggtc gtcgccgatg tacggcagca cgacgaagcc
     5701 gtcggccacc agccgttccg ccgcgtcgaa ggtctcgatc ggatcgggca gcagggtccg
     5761 ctcgtcggcg atgacctcca gcttgaccca gttggtctcc agcgcctcgc gggccagccg
     5821 ggcggtcagc acggcctcgc cggccgtgaa gcagccggcc gtgttcggca gcaccttgat
     5881 gtccctcgac cgcagcaggt cgagcaccga gccgcgggcg gccgggtcca gcctgcgcat
     5941 cgcgacggtg gtcagctcgg tgccggaggc ctccagcgcc tggtcgagca cctccagcga
     6001 cggcgcgccg ccggtcccca tgatcagccg cgaggcgaac ttctccccgc cgagcacgaa
     6061 gacgtcgccg gaggcgtcct gttccgtcat tcccgtcatc ctcccttcaa ccaccctgca
     6121 ccgcggtgag cacctcgacg ccgtcgccgt cctccacccg tgtggagtcc caggcgccgc
     6181 ggctcaccac ctcgccgttg accgccaccg cgacgcccga cgtgagcgcc gtgagggtcc
     6241 gtacggcgtc gcccaccgtc gccccctccg gcagctcggc cgggcctccg ttgatcgtga
     6301 ccttcatgag tggaatctcc ctgggtcgca ggacagggcg gcctccggca ccgcgccgcc
     6361 ggtgaggagc gcggcgacgg cctcggcggt gaccggggcc agcagcacgc cgttccggcc
     6421 gtgcccggtc gccgcgagga cgccgggggg cccggtgggg ccgatgagcg gaaggttgtc
     6481 cggggtcccc gggcggaagc cgacggccgt ctcggccagt tcgagctcgg tgaggccggg
     6541 caccagttcg cgggcgtcgc gcagcagctc gtacaccccg ccggcggtga cccgcgcgtc
     6601 gtatcccagc tcctcggagg tggcgcccag gacgatctcg ccgtcgcccc gggggaccag
     6661 gtaggcgggg gagccgtgca ccagcccccg tacgcaccgg gtgaggaacc cccgagggcc
     6721 ccgcagccgg aggatctgcc ccttcaccgg ccgtacgggc aggccgggga gcagggcggc
     6781 cgaccacgat ccggcggcca ccacgatccg gccggccggg acggtcccgc cggacgtcag
     6841 ccgcaccgac ggggagcccc gcccggggag gacgatcccg gcggcgcgct cggccaccag
     6901 cgtgccgccc gccttctcga acgcggtcag cagcgcgcgc acgagcctgc gggggtcgac
     6961 ccaggcgtcg tcgcgggcca gcagcccgcc gcgcaccgag ggggacagca tcggctcgaa
     7021 ggagcggcac tcgcgcccgg tcagccgttc gacccgcagg ccgagcgtgc gctcgaaggc
     7081 cgcgaggtcg tcgaggacgg ccatgtcgtc cgtgccgcgg gcgacctcca gcgtgccctc
     7141 ggtgcggtag tcgagctcgg cgccggactc gtcctccagc tccgcccgga acgccggcca
     7201 ggtggccagc gacgccagcc cgagccgcag cagcggctcc tccgtgtagg tcacctcgct
     7261 gaccggcgcg agcatcccgg cggcggcgtg ggtggcgccg cttcccggcg cggggtccac
     7321 cacggcaacg gaaaggccgc gccgcgccgt acgccaggcg gcggcgaggc ccgccacgcc
     7381 gcctcccacg atcacgacgt cgtggccggg ctcgctcccg gagggccgtg tggaggacac
     7441 cgcgctccct tcgccggcat tacccggatc aggtggtggg cggtcgagag ccgaacgctc
     7501 tcctctcagc ccggtccgcc gggctcccgc gcgtcttacg ccccacagcg tagtacgtgg
     7561 cggataccgg cggatcgccc ggttcgccac tcgcgggcac gggcgtgacc tggctcacaa
     7621 tcggggctgc ccgggatgtg cgcgctcctt gcccaactcg ttatggggag cccgttggcc
     7681 aggtcccctg ttgacaatct atggtcaagg cgtggatcac gtcgtggtgg tgggtgccgg
     7741 cctggccggc gtgcgaagca tcgaggcgct gaggtcccgg gggttcaccg ggcgcatcac
     7801 gctcatcggc gaggaacacc atcgccccta tgaccgcccg ccgctgtcga aggcggtgct
     7861 gctcggcgac gccgactcca ccgtggtcga ctccgacctc gacgccatgg acgtgcggct
     7921 gtgcctcggc acggccgcca agggcctgcg ggacggcgtg ctggagacga ccgagggcga
     7981 gctggagtac gacggcctgg tcatcgccac cggcgccacc ccggtccggc tgcggggcga
     8041 gggtcaccag cacgtgctgc gcacgatcga cgacgcgctc gcgctgcgcg agcggctggt
     8101 gcccggcgcc cgcgtggccg tcgtcggcgc cggctggatc ggtgccgagg tcgcgacggc
     8161 ggcggccaag gcggggtgcg cggtgacggt ggtggaggcg ggggagagcc cgctcgccgc
     8221 cgcgatcggc ccggcggtcg gctgtcacac gatcggctgg tacgcccggg ccggcgtcga
     8281 gctgcgcctg ggcgcgatgg tcgggacggt ggacgccgac gggctcacgc tcatgtccgg
     8341 cgcgcgggtg cccgccgacg tggtggtctc cggcgtcggg gtgcgcccct ccgtccactg
     8401 gctcaagggc tcggccgtac ggctcgacaa cggcgtgctc gtcgacgagc acctgcgcac
     8461 gtcgctgccg aacgtggtcg cggtgggcga ctgcgccaac tggtggtcgc gcaggttcgg
     8521 cacccggctg cgggtcgaac actgggacac cgcgctccag gcccccgaca cggccgccgc
     8581 cacgctgctg ggcgaggagg cggtctacga tccggtgccg tacttctggt cggagcagtt
     8641 cgaccacatg ctgcagttcg ccggccaccc gaccccggac gaccggatgc tgctgcgcgg
     8701 cgacccgcgg gcggacggga agtgggcggt gtgctggctg accccggagg accggctggc
     8761 cgcggtgttc accgtggacc ggccgcgcga cgtggtgcag ggccgccgcc tggtggaggg
     8821 cggccggagg ctcgaccccc ggcgggtggc cgatgccgcc gtgccgctcc gcgactgcat
     8881 tatggcgtaa tcgaggtgtt tcccggcggc tcgcatgtgg taatggtggt tccgtgacgc
     8941 ttactgttgc gcagatcgac cgggagaccg accagctcgt aggggagtgg ctcccacttc
     9001 cgcaggccgc cgagaagctg gggctcagca tcggccgcac caagcagcta ctgaaggaca
     9061 agaagctcgt cggcgcccgg cggagtggag gcggccagcc gcagatcccg tcggtgttcg
     9121 tcgcccacgg cgacgtgctc aagggcctgc ccggcacgct caccgtcctg gccgacgccg
     9181 ggtacgacga ggtggagtcg atccgctggt tgttcacccc cgacgactcg ttgccggggt
     9241 caccgatcga cgcgatcgtc aagggccggc acaccgaggt caagcgcagg gcccaggcgc
     9301 tgggcttctg accgcccgcc gcatggcatt gttggtcggg tgaacgacac ccggcgacgg
     9361 ctcgcgcagg ccaggctcta cctctgcacc gacggcagga gggaccgcgg cgacctcgag
     9421 gacttcctcg acgcggtcct ggccggcggc gtggacatcg tccagctgcg ggagaagggc
     9481 ctggaggccc gcgaggagct gggcctgctg gaggtgttcc gcgcggcatg cgaccggcac
     9541 ggcgcgctgc tggcggtaaa cgaccgggcg gacgtcgcgt acgccgcccg gccggacatc
     9601 ctgcacctcg gtcaggacga cctcccggtc cccgtggccc gggagatcct gggctccggc
     9661 gtgctcgtcg gcaggtcgac ccactcggcg gccgaggcat cggccgccgc ggtggagccg
     9721 ggcgtggact acttctgctg cgggccggtg tggcccacgc cgaccaagcc gggccgtccg
     9781 gcgcccggcc ccgcgctgct ggagcacgcc gcgagcctgg gcaccgaccg gccgtggttc
     9841 ggcatcggcg gcatcggccc ggacaacctc gacgaggtga tggcgcacgg cgtgcgccgg
     9901 gcggtggtcg tcagggccgt caccgaggcc gaggaccccg gagccgcggc cgcggctctc
     9961 aaggcgcgcc tgtcggccgt cccgctgtga gccgggccgg tcaggtgcgg cgcgaggtgg
    10021 cggcgacggc cagggcggcc agcgcggcgc gggcgtcctc ctcgatcggc gcctgttcga
    10081 gggcgtgcat cgcctcgtcc agatagcgct tgatcatgtc ctcgcagtcc gtcagcgcgc
    10141 cggtctcctc gatcagcgtg cgcagcgacg cgaccccgtc ggcgtcgagc ccggggtcgc
    10201 ccagcagggt ccgtacgacg tcctgctggg cgggggtggc cccggcgagc gcccgcgcga
    10261 tgagcacggt ccgcttgccc tcgcgcaggt cgtccccggc gggcttgccg gtctcggccg
    10321 ggtcgccgaa cacgccgagg atgtcgtcgc ggagctggaa ggcgatgccg acccgctggc
    10381 cgtactgcac gcagaggcgg tcgatccagg ggtgccgggc ccgggcggcg agcacgagcc
    10441 cgagccgcag cggctgctcg acggaatatt taccgctctt gtaaagggcc acccgcaggg
    10501 cgctgtcgaa ggtgctctca ccctgcgcct gctccagcag atcgagatac tgcccgcaca
    10561 tcagctcggt gagcatgtag tcgtgcaggg gctgggccgc ggcgatcgcc cgggggtcga
    10621 ggccgctgcc gcgccacatc tcgccggacc acaccagcag caggttgccc agcaacacgg
    10681 ccgagccctc gccgaactgc cgcgccgacc cgtgccagcc cgcgtccgcg tgcatgcgct
    10741 cgaagcgccg gtgcgccgag ggcatgccgc ggcgtacgtc gctcgcgtcc atgacatcgt
    10801 cgtggatcag cgcactggcc tggaggagct cgagcgacgc ggcggcgaag tgcaggcccg
    10861 gctcgtctcc gcccccggcg gcgcgccagc cccagtggca gaaggcggga cgcagtcgct
    10921 tgcccccggc gaggaagtcc tccgcggcgg agagcaggac ggccaggtgc gggtcctcga
    10981 agtgtgggcg ctgccggtcg aggaactccc ggagaacgcg gtccacctcc gtacggatgt
    11041 ggtcgagcga ggcggcggaa gtggtcatgc atcagagagt aaccggggca gatcccgaca
    11101 tcacagcgca gatcccctct aaattggtca gctcgcgctg ttagggcaaa acgtccgtat
    11161 ggtccgttca gccggccggt ccacatggca agaccgcgag gccggggagc ggcccgcgcg
    11221 gtaatctttc ccgtatggct ctcggtctgc cctcgcggct ccccgatcgt gtcccgacgg
    11281 tccgcgaact gctggccgcg ggagagcgct cgttctcgtt cgagttcttc ccgccgaaga
    11341 ccgacgaggg ggagcgccag ctgtggcgcg cgatccgcga gctggaggcg ctgcggccga
    11401 cgttcgtctc cgtcacctac ggcgccggcg gctcgacccg cgaccgcacc gtggacatcg
    11461 tcgagcggct ggcccacgag acgacgctga cgcccgtggc ccacttcacc gccgtcgacc
    11521 attccatccg tgagctgcgc cacctcgtcg gccggttcgc cgacgccggg gtgcgcaaca
    11581 tcctcgccgt gcgcggcgac ccgcgtggcg gcaacccgct ggacgagtgg gtcaggcacc
    11641 ccgagggcgt cctgtacgcc gaggacctgg tgcggctgat ccgccaggcg ggcgacttct
    11701 gcgtgggggt ggcggccttc ccgtacaagc acccgaggtc ggccacgatc gagtcggaca
    11761 cgaactactt cgtgcagaag tgccgggccg gcgccgacta cgcgatcacc cagatgttct
    11821 tccgcgcgga ggactacctg cggctgcgcg accgcgtggc ggcccagggg tgcgacacgc
    11881 cgatcatccc cggcgtcatg cccgtgacgc agatgagcac gatcgcccgg tccgagcagc
    11941 tgtcgggcgc gccgttcccg ccggaggtgg ccgagcggtt cgcggccgtc gccgacgatc
    12001 cggtggcggt ccgccgcctg gggatcgagc acgccgccga gatgtgccag acgctcctgg
    12061 acgagggcgc ccccggcatc cacttcatca ccttcaaccg gtcgagcgcg acccgcgagg
    12121 tgttcaaggc gctgcacggc gtgcccgccg tcgcggggtg acccgcccgc tcagtctttc
    12181 gggaacggcg cggggccggg caacggcagc cgcaccccgg cgatgacgta ctcctcgtag
    12241 ccgccgggga agacgaaccg ggtcatcaga tcggcgaagc ccacgtcgcg atagagatgg
    12301 cgggcggccg tgggggcgtc gtgcgtggac agcacggcgg tgcgctccgg gcggccctcg
    12361 cacagcgcgt ggatcatgcg ccgcccgacg cccttgccct gatactcggg gcgcacgtgg
    12421 atctcggcga tctccagggc gtcgccgaac cactcgtcgg ccaccaccgg gcccgcccgg
    12481 tcctgcaggc ccccgcggac gacgtcgtgc caccactggc cggggccgcc gtggaagccg
    12541 tacgcgaagc cggcgatgcc cgggccctgc gggtcctcgg cgaggacgca ggcgaagtcg
    12601 ggataggcgg cgtggttgcg cattatcgcc atgcggcccg cgagctggtc cgacggcggc
    12661 cgcatggcgt ccgtgtagat ctccagcacg gtgtccagca ccgccctgaa cgtgtcgggc
    12721 cccacccggc gcagtcggat cacccgtcgc acactagcaa agcggcccga ggccggtcgc
    12781 ggacgtcacc cgacctcggc gggcgtgccc ccggtgatcc gtacgagctc gtcgaaggac
    12841 gtggggaaga ccgagtgggg atgcccggcg gcggcccaca cgacctcgtg cttgcccagc
    12901 caggtgtcca ccagcgtccg cacgggcgcg gggtgcccga ccggggccac gccgccgatg
    12961 ggctgcccgg tgtgctcgcg gacgaactcc ggcgtggccc tgcgcacctt cgcggctccg
    13021 acgagccgcg cgatcaggtc ggtgttcacg cgatgggccc cgctggtcag caccagcagc
    13081 ggcgcgccgt ccgcgtcgaa gatcaggctg ttggcgatcg cgccgatctc gcagccgagc
    13141 tgggccgccg ccgtggcggc cgtcggcgcg gcgtcgtcca gcacgacgac ctcaccggtc
    13201 acctgccggt cccgcagggc ctgctcgact cggacgacgt tgggatgcaa cttttccggc
    13261 acccggccac tctaaacgga ttgccaggac agactcggcc gattatcgcc acttgtgatc
    13321 acacggctcg caatcggacc gtaaggtgag tcctttgttc ggaatcaggc ttatgagggg
    13381 ttggtcatga tgagaggtcg acggcggccg gccgtggcca tgctcgccgc cgtgggggcg
    13441 gtgaccttcg cgacggcagg ggtcgccggc ccggcgcggg ccgccgcggt tccggcggga
    13501 gccgtgacgt acgcgacggc cggtctcacc ggtgtggcgc cggcgggtgc ggcgcgaacg
    13561 ctcacggcgc cggcggccgg gacgcgggga gcgctgcccg gacgggccgg gtacccgccg
    13621 ttcgaggcgc cggggaagac gctcaagctc ggcgccaagg gcggcgcggt gaaggcgctg
    13681 caagtgcggc tcaaggagct cggctacgtg cccgggagcg ccgacggccg ctacggcggg
    13741 gccaccctga cggcgctctg ggcgttccag aaggtgcagg gaatcacgcc gaccagcacg
    13801 gtcgccgccc gcacctggag ggcgctggag aacccccgcg cgccccgggt cctcgtgccc
    13861 cgcggaaagg ccggccgggt cgaggtggac ctgaccaaac aggtgatggt tctgtatcgt
    13921 tccggcgtcc cggtgctgat cagtcacatc tccagcggca gcggcgttcc ctacaccgag
    13981 tacgccgtgt ggaacggcaa gaggcaggtg ttctccggca gcgcccgcac gccgaccggc
    14041 gactacaaga ccacgtggcg ggccaggggc tggcaccggt cctacctggg gcagctctac
    14101 aacccgatct tcttcaacgg cggcatcgcc ctccacggcg cactgtcggt gccgctctac
    14161 ccggcgtcgc acggctgcgt ccggctgccg atgaacgtcg ccgagatcct gccgggcatg
    14221 ctcggcaagg gtgttcccgt gcacgtcaga ggcgccttcc ggcgatagcc cgctgatggg
    14281 agggccccgc gcgacgcgat cgcgcggggc ccttcgtcgt acgtgccccc gtcagtcctc
    14341 gaacccttgt tcgttgacag ccttgacagc ggccatgatc gaatctatgt tcgatggagt
    14401 gggcgcggga ctcgcggcct gcgcccacac cgtcggatcc gtgcctacgt cgtcggcgga
    14461 gacggatacg gcacggcccg cggcgtgggc cggacgggga gaggggaagc tcctcgtccg
    14521 gccgcccacg ggagcgtgag aaggcgtgtg gtcccggtgg tgcccgggat tacgcggccg
    14581 agcgaaattg tcggtgctgt ctgcgactgt gaagtcaccg gtggaattcg ccggatgcca
    14641 cgactcaagg aggcgggcat gactgaagag aacggtgatc agcggaccgg gccccggctt
    14701 ccgcaggcgg tcctggcgcg tctcgcggac gccagggcgt gcctcgcgga cgccaccgtc
    14761 gggaccacgc ccgcggaccg ctacgtgtcg gcccatctcg cggcgctgcg cgcggccgcg
    14821 gggatcctcg ccgcgcgccc ccgcccgatg gacggacgca ggcggcggct gcgcagcgcc
    14881 tgggagctgc ttcccgaggc cgagccgaag ctcgcggact gggcggccta cttcgcgatg
    14941 agcgcgacca agcgagcggc ggtcgaggcc ggaatggtcc gggccgtcac tcagaacgac
    15001 gcagacgaga tcatagcgga agcggacagg ttcgtcggcg aggtcgagtc gatcctcggc
    15061 ctgcccggcc gccccaccct cccgatggcc ggctgacgcg tcaggccgga tcgcgctcca
    15121 gagggcagct catgcagcgg ggcccgcccc gtccccggcc gagttcgctg ccgcggatcg
    15181 ggatgacctc gatgccgtgc ctgcgcaggt ggttgttggt cgtggtgttg cgctcgtagg
    15241 cgacgaccac tcccggctcc agggccagca cgttgcagcc gtcgtcccac tgctcgcgct
    15301 cggccgcgtg cacgtcctgc gtcggcgtga ggaccttgat gtcgtccagg ccgagggccc
    15361 gtgcgatcgc ccggtgcatg tcctcgggcg gatggtcgac gaccttcagc tccttgtcgg
    15421 tgtcgcccgg ctccaccgtg tacgacggca gcatgccgag cccggcgtac ttcgtgaaca
    15481 cccccacgtc gacgttggtc atcacggtgt cgaggtgcat gaaggcgcgg gtcttgggga
    15541 ggtcgagcgc cacgatgcgg gtcgccgcgc ccgcgcggaa gaggttcgtc gccagcatct
    15601 cgaccgcctg cggctgggtg cgctcgctca tcccgacgag cacgacaccg tcgccgagca
    15661 ccagcacgtc gccgccctcg atggtggccg gggccatgcg ggtgccgtcg taccagacgt
    15721 cgaacccccc gccggacggg tcgccgtagc ccggggcgaa catcgggtgc caccggtaga
    15781 ccgcctcgta gttgagggtc tcgcgcctgc gcgccttctt gcgcatggcg ttgatggaca
    15841 ccccgccgta cacccagcag gaggtgtcgc gggcgaacag gtggttcggc agcggcggga
    15901 ggacgaagtc gtccaggccg agggcgtgga agacgaccga ccccgggtcg cagcccagct
    15961 ccctgatctc gcgcttggtg atcccgccgg tcaggtacgg cgcgagcgcg gcgccgtcga
    16021 gggcgtccag cgtgttgcgg atcgcgtcgg cggccagcgg gccgaaccag tgctcgtcga
    16081 cgctgccgtc gaggatgtgc ttgcgcgcgt cggggacctc gatcacctcc cgcaggagat
    16141 cgccgaggtg gtgcaccgtg acgccgcgcg cggtgagcac ctcgcaccac tcacggtgct
    16201 cctccagcgc gcgctgcacc cagagcacgt cgtcgaagag caggccgtcc ttgttgccgg
    16261 gggtgagccg cttgagcgcc agttcgggga tgtcgaccag gacctggcgg agcctgccca
    16321 cctccgagcc cacgaagaaa gtcatgtccc gtcctatccc cgcatgacag gaatcactcg
    16381 tgaggtggct ccccggcgcg caggggaccg acgggggccg ccgcggcggc ccggcggccg
    16441 gaaggagcgg tcggaaggag tggtcagaag gactcgacgg cgcggcgggc ctcggcgtcg
    16501 agcacgcccc agttgatgaa ctcctcggtc agctcgacgg gtgacttgtc gtagatgacc
    16561 gccagcgagc gcaggtcctc ctgccggatg gacagcacct tgccgttgta gtcaccccgc
    16621 tggctctgga tcgtggccgc gtagcgggcc agcggaccgg ccttgtcctt cggcagctgc
    16681 gacagccgct ccaggtcgat gaccagcttg ggagccggcg cgagcgggct gggcgcggcc
    16741 ccgccgggca gcaactcgga gaccggcacc ccgtagaagt ccgcgagttc ggcgagcttc
    16801 tgcacggtca ccgcacggtc gccccgctca taggagccca cgacgacggc cttccaccgg
    16861 ccgcgggact tctcttcgac accgtgcagg gacaacccct gctgggtccg gatggcgcgc
    16921 aggcgcgcgc ccagcgactt ggcgtagtca gacggcatcg tgtggccccc ggctttctat
    16981 gtctcttctc acttgattgt gcgtccttgt cctaagcgtt ccgaacaccg gggctggcac
    17041 cgggactggc actgggcccg gcaccttcgg tgaccgctgc gtcgggtttt acccaggaag
    17101 gtcgcgtgtt gtggttacgg acagtgacgg taaagccgac actcccaaag gtcaagctga
    17161 ttggaaaaaa gagcgccaaa cagtgctctc accgaaatcc ccgacacccg atgtgatgcg
    17221 gcttccgatc cgtcgagggc cgggtgcggg tgccgccctc ccggcgcatc acccctggcg
    17281 ggagggggga tgacggaggg ccctgatact ctatgcagac ctgacaccct tttaagaccc
    17341 gtcccgtgag gcgggaaagg tggtgacttt ttcatgtccg atgcccaaaa tcaggcccgt
    17401 gccgtcctgg aggggcccga catccaccgg gcgctcacgc ggatcgcgca cgagatcctg
    17461 gagcggacga gaggcgccga gagcgtcgtc ctgctcggca tccccacccg cggcgccacc
    17521 ctggcccacc ggatcgccgg ccggatcgcg cagttcgagg ggatcaaggt ccccgtcggc
    17581 gcgatcgaca tcacgatgta ccgcgacgac ctgcggctgc gcccggcgcg cccgctcggc
    17641 cgcaccgagc ttcccccgga cggcgtggac ggcaggaccg tcgtcctcgt ggacgacgtc
    17701 ctcttctccg ggcgcacggt gcgcgccgcg ctcgacgcgc tgaacgacgt cggcaggccc
    17761 cgggcggtcc agctcgcgac gctggtggac cgcggccacc gggagctgcc gatccgcgcc
    17821 gactacgtcg gcaagaacct gccgacctcc aagagcgaga aggtcaaggt cttcctgcag
    17881 gagacggacg ggcgcgacgc ggtcgtgctc atcaaggggg acgaccgatg aagtcgcacc
    17941 tgctctcgac cggcgacctc agccgcgacg acgccctcct catcctcgac acggcggagg
    18001 agctggcccg ggtctcgcag cggtcgatca agaagctgcc gacgctgcgc ggccggacgg
    18061 tggtgaacct cttcttcgag gactccaccc ggacccgcat ctccttcgag gccgcggcca
    18121 agcgcctgtc ggccgatgtg atcaacttct cggccaaggg gtcgagcgtg tccaagggcg
    18181 agtcgctgaa ggacaccgcg ctcaccctgg aggccatggg cgccgacgcc gtggtgatcc
    18241 ggcacagcgc ctcgggcgcg ccgcaccgcc tggccaactg ggtgcgcggc agcgtggtga
    18301 acgccggcga cggcacccac gagcacccga cgcaggcgct gctcgacgcc ttcagcatcc
    18361 gccgcaggct cggccggctc gacggactga agatctcgat cgtcggcgac gtgctgcaca
    18421 gccgggtcgc ccggtcgaac gtgctgctgc tgcacacgct cggcgccgag gtcacgctgg
    18481 tcgcgccgcc gaccctgctg ccggtggcgg tcgagagctg gccctgccag gtctcgtacg
    18541 acctcgacgc ggtgctgccg aagtcggacg tcgtgatgat gctgcgggtc cagctcgaac
    18601 ggatgaacgc ggcctacttc ccctcggcgc gggagtacag ccgccgctac ggcctcgacc
    18661 gcgaccgctt cgcccgcctg cacgacgacg cgatcgtcat gcaccccgga ccgatgaacc
    18721 gcggcatgga gatctccgcg gaggtcgccg actcgccccg atcgacgatc gtcgagcagg
    18781 tcggcaacgg cgtgacggtc cggatggccg tcctctatct gctgctcggc ggttccgagc
    18841 ccgccatcgg aggcgccgaa tgagcgcgta cgaccttcac gagggagctg tgaccaccat
    18901 cctcatcagg ggcgcccgca tcctgggcgg cgccccgcgc gacatcctgc tgcgcgacgg
    18961 cctcgtggcc gagatcggcg acctcgcggg cgccggagcg gaccagacgg tcgacgccac
    19021 cgggctggtc gccctgcccg gcctggtcga cctgcacacc catctgcgcg agcccggccg
    19081 ggaggacgcc gagaccgtcg agaccggcac ccaggccgcg gcgcgcggcg gttacaccgc
    19141 cgtccacgcg atggccaaca cctccccggt ggccgacacc gccggggtgg tcgagcaggt
    19201 ctggcggctc ggccaggagt ccggccactg cgacgtccag cccgtcggcg cggtgacctc
    19261 cggcctggag ggccgccagc tcgccgaact cggcgcgatg gccgactccg cggcccgcgt
    19321 gcgggtcttc tccgacgacg gcaggtgtgt gtcggacgcg gtgctgatgc gccgggcgct
    19381 ggagtacgtc aaggcgttcg acggcgtggt cgcccagcac gcccaggagc ccaggctgac
    19441 cgagggcgcc cagctcaacg agggcgaggt gtctgcccgg ctcggcctca ccggctggcc
    19501 ggccgtcgcg gaggaggcga tcatcgcgcg cgactgcctg ctggccgcgc acgtcggctc
    19561 ccggctgcac gtctgccacg tctccaccgc gggctccgtc gagatcatcc gatgggccaa
    19621 gtcgaagggc tgggacgtga ccgccgaggt caccccgcac cacctgctgc tgaccgactc
    19681 ccgcgcggag acctcgccgc tcgggccgta caacccgatc tacaaggtga acccgccgct
    19741 gcgcaccgcc gaggacgtgc gggcgctgcg cgaggccctc gccgacggca cgatcgactg
    19801 cgttgccacc gaccacgccc cccacccggt cgaggacaag gagaccgagt gggccgcggc
    19861 ggcgatgggc atgatcggcc tggagaccgc cctgccggtg gtccaggagg ccatggtcga
    19921 gaccgggctg ctcgactggg ccggcgtcgc cgaccgcatg tccgcgcggc cggccaggat
    19981 cggccgcctg gccgggcacg gccggcccat cgagcccggc gcgcccgcca acgtcaccct
    20041 gtacgacccg tccgtccggc gtcccgtgga ccccaccgcg atggcgtcga agagccggaa
    20101 caccccgtac gaggggatga ccctgcccgg ccgcgtggtc gccacgttcc tgcgcggccg
    20161 ccccaccgtt ctcgaaggga agctcgtatg acagccctgc tggttctcga ggacggacgc
    20221 gtcttcgagg gaacgccgta cggcgccgtg ggtgagacgt tcggcgagat ggtcttcaac
    20281 accggcatga ccggctacca ggagaccctc accgacccct cctaccaccg ccagatcgtg
    20341 gcgatgaccg ccccccacat cggcaacacc ggcgtgaacg acgaggaccc cgagtcccgc
    20401 cgcgtctggg tcgcgggcta cgtggtgcgc gagccgtcgc ggatcccgtc caactggcgc
    20461 tcccgccgga cgctcgacga ctacctgcgc gagcagggcg tcgtcggcat cgccatgtcc
    20521 ggcacccggg ccctcacccg ccacctgcgc gagcgcggcg cgatgcgcgc cggcgtcttc
    20581 agcgagggcg gcgacgtgga cgaactggtc gagcgcgtgc ggcgctcgcc cggcatggag
    20641 ggcgccgacc tcgcccgcga ggtcagcacg cccgagccgt acgtcgtgcc ggcgcgcggg
    20701 cgcaagcgct tcaccgtcgc cgcggtcgac ctcggcatca aggcgatgac ccccgagcgg
    20761 atggccgagc ggggctgcga ggtgcatgtg ctgcccgcca ccgccggcgc cgccgacatc
    20821 ctcgccctcg gccccgacgg cgtcttcttc tccaacggcc ccggcgaccc cgccgcggcc
    20881 gggtacgcgg tcgagtcgct gcgcgaggtg ctggacgcga gcgtgccgtt cttcggcatc
    20941 tgcttcggca accagatcct cggccgggcg ctcggcctcg gcacctacaa gctgcggtac
    21001 ggccaccgcg gcgtgaacca gcccgtgcag gaccgcagga ccggcaaggt cgagatctcc
    21061 gcgcacaa
//
