LOCUS       NZ_VYTZ01000003        24148 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold3, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000003
VERSION     NZ_VYTZ01000003.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 692686)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 692686)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 63777
            Orig. end                         :: 87925
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000003.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..24148
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..24148
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..24148
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:14148](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14148
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     misc_feature    806..820
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.25"
                     /tool="antismash"
     misc_feature    883..898
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 24.37"
                     /tool="antismash"
     misc_feature    complement(1571..1584)
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: medium, score: 21.16"
                     /tool="antismash"
     misc_feature    complement(2023..2038)
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: weak, score: 20.61"
                     /tool="antismash"
     misc_feature    2024..2037
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.03"
                     /tool="antismash"
     misc_feature    2024..2038
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 19.77"
                     /tool="antismash"
     gene            complement(2099..2452)
                     /locus_tag="F5972_RS08205"
                     /old_locus_tag="F5972_08205"
     CDS             complement(2099..2452)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08205"
                     /product="hypothetical protein"
                     /protein_id="WP_150932814.1"
                     /transl_table=11
                     /translation="MTTTDGPLGHSRAAHAAHGWCSHCRDRSVAEELLAWRVRENSHTG
                     CGEHDPDGPPEHDGNVPLVGEMRHGWCPTCQAASLAMATISAATTEGVTIIGGYAVCEG
                     CGWSPYADTGGLP"
     misc_feature    complement(2600..2614)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     gene            complement(2729..4468)
                     /locus_tag="F5972_RS08210"
                     /old_locus_tag="F5972_08210"
     CDS             complement(2729..4468)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08210"
                     /product="hypothetical protein"
                     /protein_id="WP_150932816.1"
                     /transl_table=11
                     /translation="MTARAPELTAAASRFVARRLRVRQVDQGWQDQAWSYFDSTPEVRF
                     AATWVGNAMSGAKLFAGRRNSEGSIDRAPDDHRAAQLVASIAGGPDGQAQLLGGFGPHL
                     VVAGEGWIMIRPDRNPAGDDTGAGADWRVLSVSEVTQQGNNLVADVDGEPVVIPPYDAD
                     QPDPDAPVAIRVWEPHPRKHMEADSPVRSSLGLLEELRLLNAAVAAIARSRLTGRGILL
                     VPKGTTFPRTKAEGDAEDDLIELLMTVAETAYKDPESAAATVPIILEVPADKIGEMRWL
                     TFESDFDELAIRLREEAIRRFATGLEMPAEILLGLGDTNHWSVWQLSQEAIRLAIEPKL
                     GTVAHALTTQWLRPLLEDEGVADAGEWLVWYDSSPLRVRQNRSEIALQVYDRNAISDEA
                     LRRETGFEEDDAPRPGAPNTQGDRADDGQERGRPADPDLPVDETMKEPDTLPASTSASA
                     GVAGEGLLAAADGLIWAALSAAGEKLIRTPACPRSERGRAKAMQPAALHTLLSVDGAHV
                     EQWRLLDGAWSRVPEIAARYGVDGDCLAASLDSYCRELIAAGVDHTWEQTAGVLRAPCL
                     VAA"
     gene            complement(4471..4851)
                     /locus_tag="F5972_RS08215"
                     /old_locus_tag="F5972_08215"
     CDS             complement(4471..4851)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF018765.5"
                     /locus_tag="F5972_RS08215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08215"
                     /product="DUF1360 domain-containing protein"
                     /protein_id="WP_225311281.1"
                     /transl_table=11
                     /translation="MIGAIAGGSRGWGQLLIGLVELGVLAFAGYRATQLVINDTILDPA
                     RDVVFRWRDRRPTSQARDWAVTLISCPYCMGWWLSGAILAVYLLVAGRWGDTSPLIHGI
                     EWFAVAGAAVLLNRADTAMGQG"
     gene            4983..5567
                     /locus_tag="F5972_RS08220"
                     /old_locus_tag="F5972_08220"
     CDS             4983..5567
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08220"
                     /product="hypothetical protein"
                     /protein_id="WP_150932818.1"
                     /transl_table=11
                     /translation="MSQEPPIPLEFFATAAQVIPVLLILLVVEERARWVAPSRAGMSLF
                     GRVTTIAATFVGEAVAMGALGVGSNPGMYPYLPLAAAAIGVMMVTMALPLLAGFLGVQW
                     ARAPLTAKVGAASLIALVSGFLPAVTAHLFLPRWPRGQGPPPTTLLDHPVVVVAEAAAL
                     AAGAFYLWTVRPSPLGEPAAGDAWRDGMNFL"
     misc_feature    5343..5345
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            5686..5973
                     /locus_tag="F5972_RS08225"
                     /old_locus_tag="F5972_08225"
     CDS             5686..5973
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) triceptide_precursor"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08225"
                     /product="hypothetical protein"
                     /protein_id="WP_150932819.1"
                     /sec_met_domain="triceptide_precursor (E-value: 1.0,
                     bitscore: 10.0, seeds: 0, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MADLKFDDDLVELQRAYVRAAEVARDLCDAFPPPTKIAAGEVVVD
                     PALEEQLEVARAERGRLVHALYGHTFWDNVADKFAAHTELQKVAAAQAGE"
     misc_feature    complement(5728..5741)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.86"
                     /tool="antismash"
     gene            complement(5991..7028)
                     /locus_tag="F5972_RS08230"
                     /old_locus_tag="F5972_08230"
     CDS             complement(5991..7028)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08230"
                     /product="hypothetical protein"
                     /protein_id="WP_150932820.1"
                     /transl_table=11
                     /translation="MVTPRTTCTTPAPLRRDPTRDALYRVGPVRVAVQTDHPPALAHLG
                     DFYCHADTGLPWWLVRGTLAEPPPGMRRDPGGAGYRADERERVLHIAARRPAVLQRALR
                     QAVREVMLAHCETRRHVMIHAAAVRRRDLLLVFAGTAGAGKTTLAVDAVVRHGFDYVAD
                     DHLILYRDDQENGGGLVATGLPTTIPVGIGTYLGMEDVLPPPWDARGVNLDSYRGWPAE
                     THRALRGRVHYTFASFGQPHPLVVTFGRGRVRVVVVQPERAARLGPLVEGGTAADLQRL
                     LATGWVASPLVHPVRLPYVRRTPLEVQADGQDVLGSLCARARMLRWAHTGRVGRLLTAL
                     GEPLA"
     misc_feature    complement(7282..7295)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.81"
                     /tool="antismash"
     gene            7319..7558
                     /locus_tag="F5972_RS08235"
                     /old_locus_tag="F5972_08235"
     CDS             7319..7558
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08235"
                     /product="hypothetical protein"
                     /protein_id="WP_150932821.1"
                     /transl_table=11
                     /translation="MALRFYGKGGSQTDSCPSVHADDTDGSLVIVGTLIEDPDVLTEIQ
                     RHSHIDPHERAVRVPRELRKALREALGEHDPDLG"
     gene            7551..8054
                     /locus_tag="F5972_RS08240"
                     /old_locus_tag="F5972_08240"
     CDS             7551..8054
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018657651.1"
                     /locus_tag="F5972_RS08240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08240"
                     /product="DUF6879 family protein"
                     /protein_id="WP_150932822.1"
                     /transl_table=11
                     /translation="MAELFARTQRSVTHLEMRDAYGAGGPDYALWREGVPIDQIAQHGN
                     VAPWVTLVGEHTARGVTFRRARIVSEPVSDYIRFEHAATGYSNQAAGERVRWLPRPRAA
                     DLALPGCDFWQFDGALVCWVFQSGDGDPAGYQLTEDPDAAKLCASAFEAVWDRGIDHEE
                     YQPA"
     gene            8069..8923
                     /locus_tag="F5972_RS08245"
                     /old_locus_tag="F5972_08245"
     CDS             8069..8923
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF040183.4"
                     /locus_tag="F5972_RS08245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08245"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_150932823.1"
                     /transl_table=11
                     /translation="MATSPSSSTQQARQAIADRLREMLRDSGLTARELARQAGWNETKC
                     SRLIHGRTPPSDNDIRAWCTICGVPEEIPNLIAASRSAETSYLEWRRVQRSMKRMQDLG
                     LSLFEDNHLYRFYSSNLVPWPLQTPSYMRAIMRRFADFHQADVPDIEAGVEARVARRRF
                     LDDGTRRCAMLIEESVLRNRIFGDDVQGEQLHHLLTGMRQPNLSLGVIPLAGRRVQKLT
                     ETFHIYGDATVSIELVSAIITITQPRDIALYVKCFNDLASSAVYGDKAKALITAAIGAL
                     EQA"
     gene            9178..9579
                     /locus_tag="F5972_RS39155"
                     /old_locus_tag="F5972_08250"
     CDS             9178..9579
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016070.5"
                     /locus_tag="F5972_RS39155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08250"
                     /product="DUF397 domain-containing protein"
                     /protein_id="WP_150932824.1"
                     /transl_table=11
                     /translation="MLATDLPGAVWRKSSRSANNCACVEVTLLGDGTIGVRDSKDPAGP
                     ALGFTPAEWDAFIGGVRDGEFDRDRLADNTRAGWPTTPGPPPPRVPRKRRPGRWQPDTG
                     KCPPARATMPGPADPAATPRERCSCPARG"
     misc_feature    complement(9591..9603)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.46"
                     /tool="antismash"
     gene            9786..9938
                     /locus_tag="F5972_RS37015"
     CDS             9786..9938
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS37015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_191910012.1"
                     /transl_table=11
                     /translation="MNNSAVLDATTADLFDLDATDVGGSLLVVDAITDNGCGTQPACRY
                     PDPQN"
     gene            10001..12835
                     /locus_tag="F5972_RS08255"
                     /old_locus_tag="F5972_08255"
     CDS             10001..12835
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016615.5"
                     /locus_tag="F5972_RS08255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08255"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_150932825.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 4.4e-123,
                     bitscore: 406.9, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 5.8e-08,
                     bitscore: 28.7, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.6e-22, bitscore:
                     75.7, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MARPIFTARTDALARIPLRPEHGHDTDDDPLLAEAITTAGGFTQH
                     APHGSASAATRRAYATRSRTRTTPQGVFAGVAPATLSAGPSIPADLRLGADHRAFTSPD
                     PLWLNLLARSIIDGSDGLSTTRVTTSNLALLRGGRWEIEQPSPGGRGRTVTIGIRDTEV
                     TAFVLRYCRNGMPAERLLAAVASRWPQAAPQAGPRLVRQLIGHGFLLHDLLPDDPRRDP
                     LTHLLDRLPSSSLLRHRLEQLRDHLAGADEHRPGDAKRLHLLTAADAITRDVLPADRVL
                     RVDTAADATVVLPADLARRAAEAAGVLWRISSGCDPLADYHRRFVTRYGTRRAVPLLEL
                     LDPVIGLGPLDDDATDIGAGPADPHGEGVLAHLLADALTDGRTEILLDEAIVDRLTNRD
                     EAPPPRTAEIYVHVLPAAEQGADHRFHLAVSGGSQDALSTTGRFLRLLRQLPHIPPDAG
                     DGHGVLIAELVARPRSDAVASVAAETGLAAHRLPVGVPARPGDLDLGDLVVFSAGGCLI
                     VWSVTRDRPVRPVLYSRITPRLLPPAARFLAAAGHSGERPWHCWSWRGLTTAPFTPAVR
                     YRGTWLAPARWALPRHLTALAGQRDRWQEALNCWRETTRPRPPDVVATDDADRRLPLDL
                     RRADDRELLRRYVRRGLTAVTAPWGAQASSSAVLPGPGGCHLLELVVSLDRAAPSPALP
                     QAAPPVRPPGQGLHLPGGPWLSLAVQAPSGCHERILQSLAPRAGDLIGRGDRWFWLRYR
                     DLRHGEHLRIRFHTDPAATGTLLASVTGWASNLHRQGLISGFCVEPYEQETERYGGREA
                     ITAAERFFAADSAFALDVLCTIREDDARLSVAAACAAAIARRIGIDGIAPARLDRPTHR
                     LAHALRSRTRAAASPWPTAWESALADYAAALPPGIGARVASDVIHMHCNRIAPDSEDIV
                     RALAADLIRTIKET"
     aSDomain        10379..10645
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_F5972_RS08255_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.50E-09"
                     /identifier="RREFam001.1"
                     /label="F5972_RS08255"
                     /locus_tag="F5972_RS08255"
                     /protein_end="215"
                     /protein_start="126"
                     /score="28.7"
                     /tool="antismash"
                     /translation="VTTSNLALLRGGRWEIEQPSPGGRGRTVTIGIRDTEVTAFVLRYC
                     RNGMPAERLLAAVASRWPQAAPQAGPRLVRQLIGHGFLLHDLLP"
     gene            12835..14148
                     /locus_tag="F5972_RS08260"
                     /old_locus_tag="F5972_08260"
     CDS             12835..14148
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.5"
                     /locus_tag="F5972_RS08260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08260"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_150932826.1"
                     /sec_met_domain="LANC_like (E-value: 8.9e-40, bitscore:
                     131.8, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTPTGTLPDARAADFAILLAERLLDPDPIITAAGPAVTSLSRGL
                     AGTALLHARLATLDPRFAAAADQHWTRAAQLLGTTPGRAGGIFNGAGALAASLILGTPY
                     LPDPGRHERSVQRGVDWLAERARLVAAWQQDRRDAGQAGTPWQTYDLINGLSGIGAVLL
                     AAARAGHTNAEPGLAAARASLTGMIHTPGEGRPGWWRPTPRHPAALADPHNRDAANTGL
                     AHGIAGPLALLSACQLAGHGNTRQAEAISVAARWLLDWQAGESWPPQITAEDLAGTSTE
                     PSTRGRRDAWCYGAPGISAALIAAGRALTDPGLAATGRRAIDALGSRTTGWDTEGPTLC
                     HGIAGVLMCAQAAGSTITADRAADALAAHYDPALPFGFRHSDHGVATDEPGLLVGAAGI
                     VLTLADRAGVPSPRVTDPWTAALLMPLAVSPDHDTDDR"
     gene            14158..15435
                     /gene="fxlM"
                     /locus_tag="F5972_RS08265"
                     /old_locus_tag="F5972_08265"
     CDS             14158..15435
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR04364.1"
                     /locus_tag="F5972_RS08265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08265"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_150932827.1"
                     /sec_met_domain="PCMT (E-value: 2.4e-42, bitscore: 140.4,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAADTLKTADRFHAELVDLLVARGTVRTGPVEAALRAVPRHAFVP
                     GAALESAYALDDAVVTKRGQDGAALSSASAPGVVAAMLEQLDVHPGDRILEIGAGTGYN
                     AALLAELTGPAGHVVTVDIDADVVDGARTALTATGYGQVEVLCADGADGHAPAGPYDRI
                     IVTAGAWDLPPAWWQQLTPDGRLVVPLRIIGGTTRSVAFDRDGGDHLVSQSMMTCGFLA
                     MRGIGAQPEPSLTLGDGVQLLLGDGRTAPPGPLAHALTQPALRTWTGITIRSGAPFQDL
                     DLWLATTGSGFCRIIAQPDAVASDLAEPAFRWGGAAVTNESDSFAYLTIRPAEPADDTG
                     TRYELGVRAHGPHRDDLAAALTEQIHRWDSDHRATTPRIDAYLKPIHRGPGQVESRRIE
                     SHQIGSDTAAAIDKPHVLLTVTWRAR"
     gene            15432..16505
                     /locus_tag="F5972_RS08270"
                     /old_locus_tag="F5972_08270"
     CDS             15432..16505
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08270"
                     /product="hypothetical protein"
                     /protein_id="WP_150932828.1"
                     /transl_table=11
                     /translation="MNGRSDVARRFPFVARARPACHRLDIRVRQVADLADAATGDPAQT
                     MTRAAEAHNLAALIASDCGLPALAADLCWTQFAIFHTARPYTAAVAKLALQPLINLGRL
                     HARTGHGTAAHHLITTVFDAVKDQTTAEVDGRTVDLTRLAQTPEDHRELVQWLWAVVLS
                     DGTRALTQACRWAEALQHVQAHHGLGQRLLDGRQIAIITHHATGDCHGAARLLAASSTP
                     TPWEQAVAAALAVLTGSPDAATMVDRYLGLDQDPPGQVVFRVRLGLAVLDLAAARTPRV
                     SNLRAAIIDGASSDAYAARDVLGHHVMRSQMTPRQEHDLTAVVTASGLGAGTLPPADMR
                     ALTTAVDKAEVALRGQL"
     gene            16723..17934
                     /locus_tag="F5972_RS08275"
                     /old_locus_tag="F5972_08275"
     CDS             16723..17934
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019630987.1"
                     /locus_tag="F5972_RS08275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08275"
                     /product="hypothetical protein"
                     /protein_id="WP_225311282.1"
                     /transl_table=11
                     /translation="MYYDAASIAHWLTGTVPNAAAIPAIVEAFTRLLGRAVTAPELGWP
                     DPGPVAVNPWDGDPVAWVTRLGRDDMLNRRTVLTAGLYTLAALNLPPTPAAAARAGQPR
                     RAGGGDVERIRAMTAQFADADSLFGGGHARTAVASYLVAEVTPLLHGTTGAARPALFTA
                     ASQLAYLAGFMANDACMAGLAQRYYIQAVRLADEAGDPVAKATALRGLALQAVEIGHPD
                     RAVHLAEAAAAALDDSCPPRVRAWMNGMRANAYAAGGDTRAAIAALTQAEGQVERAESP
                     PESQWTGAYRRASLEHDTGTTLAALSDLATGERHMVDSIRVRRGGERRSRVLITSRLAG
                     MQLRQRRVDEAAATVLGMRADLPLVSSARVAKELSALRAGWTGARSPGSRVEEADRLIA
                     SVTR"
     misc_feature    18025..18040
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: strong,
                     score: 19.52"
                     /tool="antismash"
     misc_feature    18123..18138
                     /note="TFBS match to LexA_variant_1, Repressor of DNA
                     damage response, confidence: medium, score: 24.66"
                     /tool="antismash"
     misc_feature    complement(18125..18136)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.69"
                     /tool="antismash"
     misc_feature    18150..18163
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.93"
                     /tool="antismash"
     gene            18252..18710
                     /locus_tag="F5972_RS08280"
                     /old_locus_tag="F5972_08280"
     CDS             18252..18710
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF024671.5"
                     /locus_tag="F5972_RS08280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08280"
                     /product="Panacea domain-containing protein"
                     /protein_id="WP_150932829.1"
                     /transl_table=11
                     /translation="MARIKDVAAYILAKCGPMTAMKLQKLCYYAYGYHLAWEGRPLFRA
                     PFEAWANGPVAPALYGLHRGRFQLDAGDIPGDPGVLDDGERESVDVVLDNLGKLSAHDL
                     SEMTHREAPWVNARKRANVGPLERSSEPLDDDEIYEFFDALVSADGQQ"
     gene            18697..19146
                     /locus_tag="F5972_RS08285"
                     /old_locus_tag="F5972_08285"
     CDS             18697..19146
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08285"
                     /product="hypothetical protein"
                     /protein_id="WP_150932830.1"
                     /transl_table=11
                     /translation="MGSSKKKVSAPAKTGKGNKPFVASRSLLPRAETSDSRIAWRFCHV
                     DHAGPWGFGDLTFAQIMDKLRAFESMTCREIFDQGEEPGKHYDVAALPNKVAIDRLEAL
                     NLGDMTKISRLRLGGAIRLYGFLEGNVFHVVWWDPEHQVWPSTRR"
     gene            complement(19170..19502)
                     /locus_tag="F5972_RS08290"
                     /old_locus_tag="F5972_08290"
     CDS             complement(19170..19502)
                     /GO_function="GO:0043856 - anti-sigma factor antagonist
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:TIGR00377.1"
                     /locus_tag="F5972_RS08290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_08290"
                     /product="STAS domain-containing protein"
                     /protein_id="WP_150932831.1"
                     /transl_table=11
                     /translation="MNHLRITTRPDGPRVVLVADGELDAASSDLLRAAFEEVVQAGQHT
                     VVDVSALTFCDSSSLRLLLSLRDRCAAGGGRLVLAGARGVLARLLHITGLNRAFVLAES
                     VEAAAC"
     gene            19730..20419
                     /locus_tag="F5972_RS08295"
                     /old_locus_tag="F5972_08295"
     CDS             19730..20419
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08295"
                     /product="hypothetical protein"
                     /protein_id="WP_150932832.1"
                     /transl_table=11
                     /translation="MGGFTGVWTLVGACIGAVTTLLAVWLKHKFERQRFKLFWRVMEVV
                     PIVTDETRDHLTLFHNSVPVKDPHTVKFRLDAEGPNDLDADAFKQPIKAEIGAKILDVV
                     KEEAIPSSPPALPRHWNGNTLLIDPGHIGRQQQVTYTLLVEQKPPRPTKDKVTGSLVNV
                     DLLPYPTGPSRKRTLFQSVCVLVGVALSVGASFSEFFTGANSITVGVTIIGFVLFILAF
                     PWRIVKG"
     misc_feature    20297..20299
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(20620..21075)
                     /locus_tag="F5972_RS08300"
                     /old_locus_tag="F5972_08300"
     CDS             complement(20620..21075)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08300"
                     /product="hypothetical protein"
                     /protein_id="WP_150932833.1"
                     /transl_table=11
                     /translation="MTMGPIDARPFLWVEDLPGVPSALLYVSPLIGDPAVEVLPAALSV
                     LGLPYTRVEGPSFVLQDAGRGWRCTLTRARWLSVTRRGTTLVEVERMDAPPGWVEAALA
                     EGQLLVMAGPPIPAVAGERTSAEQVLGWAASRPSCSGLVPVVEGVRG"
     gene            complement(21072..21572)
                     /locus_tag="F5972_RS08305"
                     /old_locus_tag="F5972_08305"
     CDS             complement(21072..21572)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08305"
                     /product="hypothetical protein"
                     /protein_id="WP_150932834.1"
                     /transl_table=11
                     /translation="MITLDEAKQVLPVGRRVRHLYLDWAGEVAPRPEGRPGAGRVHDSD
                     VSGNCCSVNIAWDHGEHLWTSPRELVWERDGDPPPDPLLAFAQAVSAIGRSMEVTHRTM
                     QASGAMGLAFRGDLDRLRDRLRELPPEQVRGIHDAARVLCEVTAEAPGDAAGPGGQRGV
                     AGP"
     gene            complement(21848..22000)
                     /locus_tag="F5972_RS37020"
     CDS             complement(21848..22000)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS37020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_191910013.1"
                     /transl_table=11
                     /translation="MERGLHMAQAEVVREVYALYADGVFDTEELAEHLNREGVPTPREL
                     MRRPD"
     gene            complement(22081..22215)
                     /locus_tag="F5972_RS38765"
     CDS             complement(22081..22215)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS38765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_263641805.1"
                     /transl_table=11
                     /translation="MSGAGAGRSFTYARTFQLRSGVVCDLAYTPPAWARRLLALLRRR"
     gene            complement(22212..22823)
                     /locus_tag="F5972_RS08310"
                     /old_locus_tag="F5972_08310"
     CDS             complement(22212..22823)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08310"
                     /product="hypothetical protein"
                     /protein_id="WP_150932835.1"
                     /transl_table=11
                     /translation="MTDHPMDDDLVAGPPEGSAPLWFHDGELSLLRRQMQAAQADLAQA
                     EGDAPPGFGVPPALREARLRAATLEERFARCLIGLVAAPRGAEGDLVARVLAAVADQEQ
                     RLELETLARLAGDDSGAAAAALLRTAAVRLGAVDVARTPDVAEVVHDLAEGLTALVPVV
                     RDLFGRVDADDADLGETVDALESAAGGVRVLDLHAQREGL"
     gene            complement(22838..23194)
                     /locus_tag="F5972_RS08315"
                     /old_locus_tag="F5972_08315"
     CDS             complement(22838..23194)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08315"
                     /product="hypothetical protein"
                     /protein_id="WP_150932836.1"
                     /transl_table=11
                     /translation="MGEDPPADGRYVRRSMTVPNDLSSLCGGCHAAMNEPHRPGCAKAR
                     CPYCGGQRYDCHEPPGCEVFGGVIDDKPSMWWGRWPQDIAAERYGVDKREIFDLIEVGL
                     FVWDPDTQLFKPAD"
     gene            complement(23187..23594)
                     /locus_tag="F5972_RS08320"
                     /old_locus_tag="F5972_08320"
     CDS             complement(23187..23594)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS08320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_08320"
                     /product="hypothetical protein"
                     /protein_id="WP_150932837.1"
                     /transl_table=11
                     /translation="MTTDDEWSPYDVWRGLRDAHQFEVRPEHIRLLRRANTAWEGHRDV
                     GAPSLDRRHPFGDSDDVYADMAEIVDGRTDGGYDDEDVDRYDRLRGELGLVLEIVLQAG
                     SFEPGHYERTPGGMWRHAVAIDTPGGEQAGG"
ORIGIN
        1 acgccggggt cctgggccag cgcccgcagc gcggcgaccg gcaccgtgcc gtccggggtg
       61 gtcgtccact gcaccgcccg cctggtgcgg accggccccg cggcggcggc gacctcacca
      121 tgggacgtca ccgacaccag ccacgacccg tccgggaggg gcagggcgga cgcgtgggcg
      181 gcggacgcca gcagcaccac ctccccgccg tccccttcgc tggtggtgcg gtcgatgaac
      241 tcaatgtcga cgtcgtccag gtccacgctg acgccgaggg gcgcgccctc gtcgagcagc
      301 ctttccgccg ccaggcccgc cggctgcgac cggtacaggt caccggcgcc ggggatgcgg
      361 tccccggccc ggtccaggtc ctggatgtcg ccggcgagct ccgccccctc gtgcccgccg
      421 agcatttcgt cggcgaactg cagcggccac ggcccgccct cccagtacag ggcgttcggc
      481 gcgaagatcc ggccgtcgcc ggtctcgacg ttctcgaacg cgagcgcggt gtcgccgggg
      541 gtggaccagc ggcggcgctg cgaccggtcg gcggctgcgg tctgatcggg catggtgtct
      601 ccgtcctgtc ctcgaccgag cgggatgtcg gtcacctcgc cgccgaacgc cacccgcagc
      661 cggtcgaacg tgatgggccc ggtgcggtcg gccagctggg cgacctgcgc caggtctccg
      721 gtgtaggtga gggtgacgtg cggcacccac ggggtgtgct gctccggcag gtcgaacagg
      781 cccgacacga tgtagctggc ggagcggtgc atgtcggcca ggccgggccc gccgacgccg
      841 agcacgatgc acgggtcccg ttcgtcgtcg gccgggttga acacgctgat ggcgaacgcg
      901 ttggcttcca gcggctgcag cccgtccggc tggtccatct gtccgggcat ctcggaggcc
      961 agcgcgtcgg tgatcgccgc ccgggtgggg gcgtcgatgg cgtcggcgtc gccgaggaac
     1021 agcagcgtca ggtgcaggtc ctccggcagt tcgccgccgg gcacggccag gcgctcaatg
     1081 tccgcctggg aggggaccag cgccaccatc cccccggtgt acgggccgcc tgaggcggcg
     1141 gacaggtcgg gttgcgggtg ggcgtcacgc acgattccct gctcctggta gtagtcgacg
     1201 acctggcgga tctgctcgtc ggtgaggtac tggcggccgt cgtccggtgg cggggtcggc
     1261 tcgtacccga acaccgccgt gcaccggcac tggatggtgt tggcggggga gccggtgggg
     1321 tcgccggggt actgcagcgg ctcgccctcc accaggaacg gcgcgacgac cggcacggtc
     1381 tgcccgtcgg cggcgaagtg cccggggcgt gtgcggcggt ccatcgtcgc gagccacgtc
     1441 ttgaagccgg gccgcacctc cgaaggcatc gcgtgcaccg cgtccaggct ggcgcggttc
     1501 caggcggcgg cggtttcggt gcgggcgatg cgctccgccc gggtgtcgcc cagcaccgcc
     1561 ccgtcttccg caaaggtgcg tttgagccgg tcgcggagct ggttgacgcc ttccccggcg
     1621 gccatgccgt cggcgagggc ctgccgggcg gcctgccaca ggttgtcgcc cacggcggcg
     1681 aggcggttct ccgcctcccg catgtacgcc tgcgccgcct ccggcacgct gaacgggtcg
     1741 tccagccagc gcggcaccag gtcgtcgctg ccgggcggcg gcggcacgtc gaaccggcgt
     1801 agcaccgcgt ggaacgccgc ctcccacacc gcgagcagca ccgcgaggat ccgccgcagc
     1861 agcccccgcc acagcgtgcc tgggcggcgc aggtcggcgt cgtcgatcgg gtcgccgtcc
     1921 gccgccacca gccgatgcag cacggcgagg ggcaggccgg acgcctccag cgaccggccg
     1981 aactcctcgg ccacctcgtc cagcacgtcg gccaccgcgc gttcgaccat gcgttccagg
     2041 ccggtcaacg tccggtcggc ggcgtcgcgg gcggcctgcc tcgggtcctt gccgccggtc
     2101 atggcaggcc cccggtgtcg gcgtacgggg accagccgca gccctcgcac accgcgtacc
     2161 ccccgatgat cgtcacgcct tcggtggtgg cggcgctgat cgtcgccatc gccaggctcg
     2221 ccgcctggca ggtggggcac cacccgtgcc gcatctcacc gaccagcggc acgttcccgt
     2281 cgtgctcggg cggcccgtcc gggtcgtgtt cgccgcaacc ggtgtggctg ttctcccgca
     2341 cccgccacgc caacagctcc tccgccaccg accggtcccg gcagtgcgag caccagccgt
     2401 gcgcggcgtg cgcggccctg ctgtgcccca gcggcccgtc cgtcgtcgtc atgcggccac
     2461 caggcaggag gcgcgcaaca cacccgtggt ctgctcccgt gtgtggtcgg cacccgctgg
     2521 tgccgccttc gcgacatggg gacgctcacg cctgccagcc atcacgcctg ccctccgcac
     2581 gagcatcccc cgacgcagca gcgaggggac tgatcttcga ggtcctcgat gtcgtgcagc
     2641 acgccgccat gggggcacgg ggggacgttc gggcaggccc accatcgcaa ccatctacgc
     2701 accccttctt gagccggcgc cgtcgtcgtc atgcggccac caggcagggg gcgcgcaaca
     2761 cgcccgcggt ctgctcccac gtgtggtcga ccccggccgc gatcagctcc cggcagtagg
     2821 agtccagcga cgcggccagg cagtcgccgt cgacgccgta ccgggcggcg atctccggca
     2881 cccgcgacca cgccccgtcc agcaaccgcc actgctccac gtgcgcgccg tccaccgaca
     2941 gcagggtgtg cagcgcggcc ggctgcatcg ccttcgcccg gccgcgttcg ctcctcgggc
     3001 aggcgggggt gcggatcagt ttctccccgg ccgccgacag cgccgcccag atcagcccgt
     3061 ccgctgcggc cagcaacccc tcacccgcca cccccgccga ggcggaggtg gaggcgggca
     3121 gcgtgtccgg ctccttcatg gtttcgtcca ccggcaggtc cgggtcggcc ggacgcccgc
     3181 gttcctggcc gtcgtcggcg cggtcgccct gcgtgttcgg ggcgccgggc cgcggcgcgt
     3241 cgtcctcctc gaaccccgtc tcccggcgca gcgcctcgtc ggagatggcg ttgcggtcgt
     3301 acacctgcag cgcgatctcc gaccggttct gccgcacccg cagcggtgag gagtcgtacc
     3361 agaccagcca ctccccggcg tcggccacgc cttcgtcttc cagcaggggc cgcagccact
     3421 gcgtggtcag ggcgtgggcg acggtgccca gcttcggctc gatcgccagg cggatcgcct
     3481 cctggctcaa ctgccagact gaccagtgat tggtgtcgcc gaggccgagc aggatttccg
     3541 ctggcatttc caggccggtg gcgaatcggc ggatggcctc ctcccgcagg cggatcgcca
     3601 gctcgtcgaa gtccgactcg aacgtcagcc accgcatctc gccgatcttg tcggcgggga
     3661 cctccaggat gatcggcacc gtggcggccg ccgactcggg gtccttgtac gccgtttcgg
     3721 ccaccgtcat cagcagctcg atcaggtcgt cttcggcgtc gccctccgcc ttcgtgcggg
     3781 ggaacgtggt gcccttcggc accagcagaa tcccgcgccc cgtcaggcgg gacctcgcga
     3841 tggcggcgac ggcggcgttc agcagccgca actcctccaa cagcccgagc gacgaccgca
     3901 cgggggagtc ggcctccatg tgcttacgcg ggtgcggctc ccacacccgg atcgcgaccg
     3961 gcgcgtccgg gtccggctgg tcggcgtcgt acggcgggat caccacgggt tcgccgtcga
     4021 cgtcggcgac caggttgttg ccctgctggg tgacctccga caccgacagg acccgccagt
     4081 ccgcgcccgc cccggtgtcg tcgccggccg ggttgcggtc ggggcggatc atgatccacc
     4141 cttccccggc gacgaccagg tgggggccga agccgccgag cagctgcgcc tgcccgtccg
     4201 ggccgcccgc gatggaggcg accagctgcg cggcgcggtg gtcgtcgggg gcgcggtcga
     4261 tgctgccctc actgttgcgg cggcccgcga acagcttcgc ccccgacatg gcgttgccga
     4321 cccaggtggc ggcgaaccgc acctccggtg tgctgtcgaa gtacgaccat gcctggtcct
     4381 gccagccctg gtcgacctgg cggacccgca ggcggcgggc gacgaaccgg gaggcggcgg
     4441 cggtgagctc cggggcgcgg gccgtcacgg tcacccctgg cccatggccg tgtcggcgcg
     4501 gttcagcagc acggccgccc ccgccacggc gaaccactcg atgccgtgga tcagcggcga
     4561 ggtgtcgccc cagcggcccg cgaccagcag gtacacggcg aggatcgcgc cggacagcca
     4621 ccagcccatg cagtacgggc aggagatgag ggtgaccgcc cagtcccggg cctgggaggt
     4681 ggggcggcgg tcgcgccacc ggaacaccac atcccgcgct gggtccaaaa tcgtgtcatt
     4741 gatcaccaat tgggttgctc tgtaacccgc gaaggccagc acgccaagct caaccagccc
     4801 gatcaacagc tgcccccaac cgcgcgatcc cccggctatc gcgccgatca taggaccgct
     4861 atccgtaaat cttccggtgc ggaagccata cagcaggaag atttacggac tttgggggtt
     4921 gggggtgagc gcgtcgcggc cggacggcgt aaccagccgg gcatggcagc cgatcatcgg
     4981 gtatgagtca ggagcccccc atccctctgg agttcttcgc caccgccgcc caggtgatac
     5041 cggttctgct catcctgctg gtcgttgagg agcgcgcccg gtgggtcgcc cccagccgcg
     5101 ccgggatgtc cctcttcggc cgggtcacga cgatcgcagc cacatttgtg ggggaggcag
     5161 tggcgatggg cgcccttggc gtcggctcca accccggcat gtacccgtac ctcccgctgg
     5221 cggcagcggc catcggcgtg atgatggtca cgatggcgct gcccttgctg gctgggttcc
     5281 taggcgtgca gtgggcccga gccccgctga cagccaaagt cggtgccgcg tccctgatcg
     5341 cgttagtctc cggcttcctc ccagccgtaa ccgctcattt gttcctgccg cggtggcccc
     5401 gtgggcaggg cccgcccccc acgacgttgc tggatcaccc tgttgtcgta gttgcagagg
     5461 ccgccgccct cgctgccggg gccttctact tgtggactgt cagaccgtct cccctggggg
     5521 agcctgcggc cggggacgcc tggcgggacg gcatgaactt cctgtaactg ccgggccggt
     5581 gacggctggg acggagaggc cgcccccggc ggccggggcg gctcccaggc cgtcaccgcg
     5641 cccgcgtacg atgcccgccc gaggggcgcg gacctggagg cggaagtggc agatctcaaa
     5701 ttcgacgatg acctggtgga gctgcagcga gcgtatgtcc gcgcggcgga ggtggcgcgg
     5761 gacctctgcg acgcattccc gcccccgacg aagatcgcgg ccggtgaggt ggtcgttgac
     5821 cccgcgcttg aggagcagct ggaggtggcc cgcgccgagc ggggccgcct tgtgcacgcc
     5881 ctgtacgggc acacgttctg ggacaacgtg gccgacaagt tcgccgccca caccgagctg
     5941 cagaaggtcg ccgccgccca ggccggggag taggaccccg gccgggccgg tcaggccagc
     6001 ggctcgccga gcgcggtcag cagccggccg acccggccgg tgtgcgccca ccgcagcatc
     6061 cgcgcccgcg cgcacaggct gcccagcacg tcctgcccgt ccgcctgcac ctccaacggt
     6121 gtgcgccgca cgtacggcaa acgcaccggg tggaccagcg gcgaggccac ccacccagtg
     6181 gccagcagcc gctgcaggtc ggcggcggtg ccgccctcca cgagcggccc cagccttgcc
     6241 gcacgctcgg gctgcacgac caccacccgc acacgccccc gcccgaacgt cacgaccagc
     6301 gggtgcggct gcccgaacga cgcgaacgtg tagtgcacgc ggccgcgcag cgccctgtgc
     6361 gtctccgccg gccacccccg gtacgagtcg aggttgacgc cgcgcgcgtc ccacggcggc
     6421 ggcagcacgt cctccatccc caggtaggtg ccgataccca cggggatcgt cgtcggcagg
     6481 cccgtcgcga ccagcccgcc cccgttctcc tggtcgtcgc ggtacaggat gaggtggtcg
     6541 tcggcgacgt agtcgaaccc gtgccgcacg accgcgtcca cggccagcgt cgtcttgccc
     6601 gccccggccg tgccggcgaa caccaacagc aggtcccggc gccgcaccgc cgccgcgtgg
     6661 atcatgacgt ggcggcgggt ttcgcagtgc gccagcatca cctcccgcac cgcctgccgc
     6721 agggcccgct gcagcacggc gggacggcgg gcggcgatgt gcagcacccg ctcccgctcg
     6781 tccgcccgat acccggcgcc gcccgggtca cggcgcatcc ccggcggcgg ctcggccagg
     6841 gtgccgcgca ccagccacca cggcagccct gtgtcggcgt ggcagtagaa gtcgcccaga
     6901 tgtgccagcg ccggcgggtg gtcggtctgc acggccaccc gcaccggccc cacccggtac
     6961 agggcgtcac gggtcgggtc gcggcgcagc ggcgcggggg tggtgcaggt ggtccggggg
     7021 gtcaccatgt cctccagtca cccccgaacg ggggcgtcga gtcgggtcac tgacgccgga
     7081 cagtcaatgc cgcggacgcg cgttccggac tccgatgcgt tttggatggt gttgcatgcg
     7141 ggtcaaatct tcggctcgac gatcgtgacc gggccccggg ataccgccgc tgagcagggc
     7201 ggaaaggggc ggcgacgcgc caccgccccg ctcaccggca ctcttgactg ctttcaccgc
     7261 cgcgcttcaa gctcgcatct gtgcaagtcc gtacaagctc tcaggcagga gttcccccat
     7321 ggcgctacgg ttctatggca agggcggcag ccagaccgac agctgcccct cggtccacgc
     7381 ggacgacacg gacggaagcc tcgtgatcgt gggcacgctc atcgaagatc cggatgtact
     7441 gaccgagatc cagcggcaca gccacatcga ccctcacgag cgggccgtcc gggtgccgcg
     7501 tgaactgcgg aaagctctga gggaggcgtt gggtgagcat gatccagatc ttggctgagt
     7561 tgttcgcgcg aacccagcgg tcggtgacac acctggagat gcgggacgct tacggcgccg
     7621 gaggccccga ctacgcgctg tggcgtgagg gcgtccccat cgaccagatc gcgcagcacg
     7681 gcaatgtcgc tccgtgggtg accctggtcg gggagcacac ggcccggggg gtcaccttcc
     7741 gccgagccag gatcgtgtcc gaaccggtca gcgactacat ccgcttcgag cacgccgcca
     7801 ccggctactc caaccaggcc gccggtgagc gggtgcgctg gctgcctcgc ccgcgtgccg
     7861 cggacctggc gcttccaggg tgcgacttct ggcagttcga cggcgccctg gtgtgctggg
     7921 tcttccaaag cggcgacggc gaccccgccg gctaccagct gaccgaagac ccggacgcgg
     7981 ccaaactgtg cgcctcggca ttcgaggccg tgtgggaccg cgggatcgac cacgaggagt
     8041 accagcccgc ctgaccgcaa gcacactcat ggccacctcc ccctcatcca gcacccagca
     8101 ggcgcgccag gcgatcgccg accggctgcg cgaaatgctg cgcgactccg gcctgaccgc
     8161 ccgggagctg gcacggcagg cggggtggaa cgaaaccaaa tgctcccgcc tcatccacgg
     8221 ccgcaccccg cccagcgaca acgacatccg cgcctggtgc accatctgcg gtgtccccga
     8281 ggagatcccc aacctgatcg ccgcctcccg cagcgccgaa acctcctacc tggaatggcg
     8341 cagggttcag cgcagcatga aacggatgca ggatctgggg ttgtcgctgt tcgaggacaa
     8401 ccacctgtac cggttctact cctccaacct cgtcccctgg ccgttgcaga cgcccagcta
     8461 catgcgggcc atcatgcgcc gcttcgccga cttccaccag gccgacgtgc ccgacatcga
     8521 ggcaggggtc gaggcgcgcg tcgcccgccg ccggttcctg gacgacggca cccgccgttg
     8581 cgcgatgctg atcgaggagt cggtgctcag aaaccggatc ttcggcgatg acgtgcaggg
     8641 cgagcagctg caccacctcc tgaccggcat gcgccagccg aacctgtcct tgggcgtcat
     8701 cccgctggcc ggtcggcgcg tgcagaaact caccgagacc ttccacatct acggcgacgc
     8761 cacggtgtcc atcgagctgg tgtcggccat catcaccatc acccagccgc gggacatcgc
     8821 cctgtacgtc aagtgcttca acgacctggc atccagcgcc gtctacgggg acaaggccaa
     8881 ggcgttgatc actgcggcga tcggcgcgct ggaacaggcg tagaagttcg tacaagtttc
     8941 tggagccgcc tcgccccggc tgtttaccgt cacgtccatg gcgatcggtc acgccagccc
     9001 cggcgccggc ccgctgcccc cctcatgctc agggcaagga ggcgtcaccc gatgccgcgc
     9061 cacgcacgcc cccggccgag cccccgcagg cccgcccatc cggccggtct gcccgcacct
     9121 cgaaagaccc ctcccgggtg tccccgggag gccgtgcgag ggacaaggag acaaaccatg
     9181 ctcgcgaccg atctgcccgg cgccgtgtgg cggaagagca gccgcagcgc caacaactgc
     9241 gcctgtgtcg aggtgacgct gctgggcgat ggcaccatcg gcgtgcggga cagcaaggac
     9301 cccgccggcc ccgccctggg tttcacccct gccgagtggg acgccttcat cggcggcgtc
     9361 cgcgacggag agttcgaccg ggaccggctg gccgacaaca cccgggccgg ctggccgaca
     9421 acacccgggc cgcctcctcc tagggtgccg cgtaagcggc ggccaggcag gtggcagccc
     9481 gacaccggga agtgcccgcc cgcacgggcg acgatgcccg gaccggctga ccctgcagcc
     9541 acccctcgtg aacgatgctc ctgcccagct cgggggtagg cagcggcgag gggacaacgg
     9601 cacatccggt tgggccacgg gcaccagcac cggttagcga aggagagcaa cagcagccgc
     9661 gctgcgggaa tcgccgcaga acggcaaccc gctgctctac accctccata ggccccctgc
     9721 ctctggtcag cggcgcgcac cagaggcagg gacagcatgc ctgcgcgcca cggaaaggca
     9781 caccaatgaa caacagcgcg gtcctggacg ccaccacggc agatctgttc gacctcgacg
     9841 ccacggacgt gggcggcagc ctcctggtcg tcgacgccat caccgacaac ggctgcggca
     9901 cgcagcccgc ctgccgctac cccgacccgc agaactgacc ccacccccgg cacggggccg
     9961 cggcattcaa ccggccgcgg ccccatggag gagacgtcct gtggctcgtc cgatcttcac
    10021 cgcccgaacc gacgcgctgg cccgcatccc cctgcgcccg gagcacggcc acgacaccga
    10081 cgacgacccg ctgctcgccg aggcgatcac aacggccggt ggcttcacgc agcacgcacc
    10141 ccacggctcg gcgtccgcgg cgaccaggcg ggcctacgcg acacgatccc ggacccgcac
    10201 caccccgcag ggcgtgttcg ccggtgtcgc gcccgcgacg ctgtccgccg gcccttccat
    10261 tccggctgac ctgcggctag gggccgacca ccgggccttc accagccccg acccgctgtg
    10321 gctgaatctg ctggcacgct cgatcatcga cggctctgac ggtttgtcca cgacgcgggt
    10381 gacgaccagc aacctcgcct tgctgcgcgg cggtcggtgg gagatcgagc agccttcccc
    10441 cggcggccgg ggacgcactg tgacaatcgg catccgcgat accgaggtga ccgcgttcgt
    10501 cctgcggtac tgcaggaacg ggatgcccgc tgagcggctg ctcgccgcgg tggcatcgcg
    10561 atggccgcaa gcagccccgc aggcggggcc acgactcgtg cgacagctga tcggccacgg
    10621 ctttctcctg catgacctgc ttcccgacga cccgcgccgt gacccgctga cgcacctgct
    10681 ggaccggctc cccagctcct cgctgctgcg ccaccggctg gaacagctcc gtgatcacct
    10741 ggccggggcc gacgagcacc ggccgggcga cgccaagcgg ctgcacctgc tcaccgccgc
    10801 cgacgcgatc acacgcgacg tcctgcccgc cgaccgtgtc ctgcgcgtgg acaccgcggc
    10861 cgacgccacc gtggtcctgc ccgccgatct ggcccgccga gccgcggaag ccgccggcgt
    10921 cctgtggcgg atcagctcgg gctgcgaccc gctcgccgac taccaccgca ggttcgtcac
    10981 ccgctacggc acccgccggg ccgtgccgct cctggaactc ctcgatcccg tcatcggcct
    11041 cggccccctc gacgacgacg ccaccgacat cggcgccggg ccagccgacc cgcacggtga
    11101 gggagtgctg gcccacctgc tggccgacgc gctgacggac ggcaggaccg agatcctttt
    11161 ggacgaggcg atcgtggacc ggctgaccaa ccgcgatgag gccccccctc cccgcacggc
    11221 cgagatctac gtgcacgtcc tgcccgcagc tgagcagggc gcggatcacc ggttccatct
    11281 ggcagtgtcc ggcggatcac aggacgcgtt gtcgacgacc ggccggttcc tccgcctgct
    11341 ccgccagctt ccgcacatcc cccccgacgc cggcgacggg cacggcgtct tgatcgccga
    11401 gctggtggcg cgtccccgct cggacgcggt cgcctccgtc gcggccgaga ccgggcttgc
    11461 cgcgcaccgg ctccccgtag gcgtcccggc ccggccgggc gatctcgacc tcggcgacct
    11521 ggtggtgttc tctgccggcg gctgcctgat cgtgtggtcg gtcacccgcg accggcccgt
    11581 gcggccggtc ctgtactcgc ggatcacgcc gcggctgctg ccgccggccg cccgcttcct
    11641 ggccgcagcg ggacattccg gggaacgtcc ctggcactgc tggtcgtggc ggggcctcac
    11701 caccgccccc ttcacccccg ctgttcgcta ccgcggcacc tggctcgcgc ccgcccgatg
    11761 ggccctgccg cggcatctga ccgccctcgc cggccaacgc gaccggtggc aggaagctct
    11821 caactgttgg cgggagacga cccggccacg ccctcccgac gtcgtggcca ccgacgacgc
    11881 agaccgtcgg cttccgctgg acctgcggcg ggccgacgac cgtgaacttc tgcgccgcta
    11941 tgtccggcgc ggcctcaccg ccgtcaccgc cccgtggggc gcccaggcat caagctcggc
    12001 cgtgctgccc ggtcccggcg gctgtcacct cctggaactg gtcgtcagcc tggaccgcgc
    12061 cgcaccttcg cccgccctcc cacaggcggc accgccggta cggccgcccg gtcagggcct
    12121 ccaccttccg ggagggcctt ggctgtcgct ggccgtccag gccccgtccg gctgccacga
    12181 gcggatcctg cagtcgctgg ccccgcgagc cggcgacctg atcgggcgcg gggaccggtg
    12241 gttctggctc cgctaccgcg acctccgcca cggcgaacac ctcaggatcc gcttccacac
    12301 cgaccccgcc gccaccggca cgctgctggc gtcggtgacc gggtgggcgt ccaacctgca
    12361 ccggcagggc ttgatctccg ggttctgcgt cgaaccctac gagcaggaga ccgagcggta
    12421 cggcgggcgc gaggccatca ccgccgccga acggttcttc gccgccgaca gcgccttcgc
    12481 actcgatgtg ctgtgcacca tccgggagga cgacgcacgc ctcagcgtcg cagcggcgtg
    12541 cgcggcggcg atcgcccgac ggatcggcat cgacgggatc gcacccgcgc ggctcgaccg
    12601 cccaacccac cgcctcgccc acgccctgcg gtcccgtaca cgtgccgccg catccccgtg
    12661 gcccaccgcg tgggaatcgg cactggccga ctacgcggcc gccctcccgc ccggcatcgg
    12721 ggcgcgggtc gcctccgacg tgatccacat gcactgcaac cggatcgcac ccgacagcga
    12781 agacatcgtc cgcgccctgg ccgccgacct gatccgcacc atcaaggaga cctgatgccg
    12841 accccgaccg gcacccttcc cgacgcccgc gccgccgact tcgcgatcct gctcgccgag
    12901 cggctcctgg atcccgaccc gatcatcacc gcggccgggc ccgccgtgac gtccctgtcg
    12961 cggggcctgg ccgggaccgc gctcctgcac gcccgcctgg ccaccctcga cccccgcttc
    13021 gcggccgcag ccgaccagca ctggacacgc gccgcacagc tgctcggcac cacccccggg
    13081 cgggccggcg gcatcttcaa cggtgccggc gccctggccg cctcactgat cctcggcacc
    13141 ccctacctgc ccgaccccgg ccgccacgaa cgctccgttc aacgcggcgt cgactggctg
    13201 gccgaacgag cccgcctcgt cgccgcctgg cagcaggacc ggcgggacgc cgggcaggcc
    13261 ggaaccccct ggcagaccta cgacctcatc aacggcctgt ccgggatcgg agcggtcctg
    13321 ctcgccgccg cccgcgccgg gcacaccaac gccgaacccg gtctcgccgc cgcccgcgcc
    13381 tccctcaccg gcatgatcca cacgcctggg gaagggcgac caggctggtg gcggccaacc
    13441 ccacggcatc ctgcggcgct tgccgaccca cacaaccgcg acgccgccaa caccggcctc
    13501 gcccacggga tcgccgggcc cctggcgctg ctttcggcct gccagcttgc cgggcacgga
    13561 aacacccgac aggccgaagc gatcagcgtc gcagcccgct ggctgctgga ctggcaggcc
    13621 ggcgaaagct ggccacccca gatcaccgcc gaagacctgg ccgggaccag caccgagccg
    13681 agtacccgtg gccgccgcga cgcctggtgc tacggagcgc cgggcatcag cgccgccctc
    13741 atcgccgcag gccgagcgct gaccgatccc ggcctggcgg cgacgggccg ccgcgcgatt
    13801 gacgccctgg ggtcccgcac caccggctgg gacaccgaag gccccaccct ctgccacggc
    13861 atcgccggtg tcctgatgtg cgcgcaggct gcgggcagca ccatcaccgc tgaccgtgcc
    13921 gccgacgccc tcgccgccca ctacgatccg gcgctgccgt tcggtttccg gcacagcgac
    13981 cacggcgtgg cgaccgacga gccggggctc ctggtcggcg cggccgggat cgtgttgacc
    14041 ctggccgacc gcgccggcgt gccctccccg cgggtgaccg atccgtggac ggccgcgctg
    14101 ctgatgcccc ttgccgtttc ccccgaccac gacaccgacg acaggtaggt tcctccgatg
    14161 gccgctgaca ccctcaagac cgccgaccgt ttccacgccg agctcgtcga cctgctggtc
    14221 gcccgcggaa ccgtccggac cgggccggtc gaggccgcgc tgcgggcggt accccggcac
    14281 gccttcgtgc ccggcgccgc cctggaatcc gcctacgcgc tcgacgacgc cgtggtcacc
    14341 aaacgcggcc aggacggtgc ggcgctcagc tcggcgtccg cgcccggcgt cgtcgccgcg
    14401 atgctggagc aactcgacgt ccaccccggc gaccgcattc tggagatcgg cgccggaacc
    14461 ggctacaacg cggccctcct cgccgaactc accggcccgg ccgggcacgt cgtcacagtc
    14521 gacatcgacg ccgacgtggt cgacggggcc cggaccgctc tgaccgccac cggctacggg
    14581 caggtcgagg tgctgtgcgc cgacggcgcc gacggccacg cccccgccgg gccctacgac
    14641 cggatcatcg tcaccgcggg agcgtgggac ctgccgcccg catggtggca gcagctcacc
    14701 ccggacgggc ggctcgtcgt cccgttgcgg atcatcggcg ggacgacacg ctccgtcgcc
    14761 ttcgaccgcg acggcggcga ccatctggtg agccagtcga tgatgacgtg cgggttcctt
    14821 gccatgcgcg gcatcggcgc ccagccagag ccctccctca ccctcgggga cggcgtccag
    14881 ctcctgctgg gcgacgggcg caccgcaccc cccgggcccc tcgctcacgc cctcacccag
    14941 cccgcgctcc gcacctggac cggcatcacc atccggtcag gggccccctt ccaggacctg
    15001 gacctgtggc tggccaccac cggtagcggt ttctgccgga tcatcgccca acccgacgcc
    15061 gtcgcctccg acctggcgga acccgcattc cgctggggcg gcgccgccgt caccaacgaa
    15121 agcgattcct tcgcctacct caccatccgc ccggccgaac cggccgacga caccggaacc
    15181 cgctatgagc ttggggttcg cgcccacggc ccgcaccgcg acgacctcgc tgcggccctc
    15241 accgagcaga tccaccggtg ggacagcgac caccgcgcca ccaccccgcg catcgacgcc
    15301 tacctcaagc ccatccaccg cgggcccggc caggtcgaat cacgccgcat cgaatcacac
    15361 cagatcggat cggacaccgc tgcggccatc gacaagccgc acgtgctgct gaccgtcacc
    15421 tggcgggcac gatgaacggc cgaagcgacg tcgcccgccg gttccccttc gttgcgcgcg
    15481 cacgacccgc ctgccaccgg ctcgacatcc gcgtccgcca ggtcgccgac ctggcggacg
    15541 ccgccaccgg cgacccggcg caaacgatga cgcgcgcggc cgaagcccac aacctggccg
    15601 cgctcatcgc cagcgactgc ggcctgccgg ccctggcagc cgacctgtgc tggacccagt
    15661 tcgccatctt ccacaccgcg cggccctaca cggcggccgt cgcgaaactc gcgcttcagc
    15721 ccctcatcaa cctcggccgc ctccacgccc gcaccggcca cggcaccgcc gcccaccacc
    15781 tgatcaccac cgttttcgac gccgtcaagg accagacgac cgccgaggtc gacggccgta
    15841 ccgtcgacct cacccgcctg gcccaaacgc ccgaagacca ccgcgagctc gtccaatggc
    15901 tgtgggccgt ggtcctgtcc gacggcaccc gcgccctcac ccaagcctgc cgctgggccg
    15961 aagcgctcca gcatgtccag gcccaccacg ggctcgggca acgactcctc gacggccgcc
    16021 agatcgcgat catcactcat cacgcgacgg gcgactgtca cggcgctgcc cgcctcctgg
    16081 ccgcatcctc cacgcccacc ccgtgggaac aagcggtcgc cgctgccctc gccgtactga
    16141 ccggcagccc cgatgccgcc acaatggtcg accgttacct cgggctcgat caggatccac
    16201 ccgggcaggt cgttttccgg gtccgtctgg gcctggccgt gctcgacctg gccgccgccc
    16261 ggacaccgcg cgtgtcgaac ctacgggccg ccatcatcga cggggcgtcc agcgacgcct
    16321 acgccgcccg agacgtcctg ggccaccacg tgatgcgctc ccagatgacc cctcggcagg
    16381 aacacgacct caccgccgta gtcaccgcat cagggctcgg tgccgggaca ctcccacccg
    16441 ccgacatgcg cgctctcacc acagccgtgg acaaggccga agtggcattg cgcgggcagt
    16501 tgtgacccgt tcaccggtta cccggccccc ggcccttggc ttgggacagc cttgggcgtt
    16561 gcaaggtccc gtatcccgcg catgagaggt ggaggcatgc ccgcggcacg acgccacccc
    16621 gtggccaatc ccgcacttca agcggcgatc caggccgccc aactccccta cgccagggtc
    16681 gcccaggcaa tccgcgcggt tggggcggaa aacgggcggg ctatgtacta tgacgcggcg
    16741 tctatcgcac actggctgac ggggaccgtc cccaacgccg ccgcgatccc cgccatcgtc
    16801 gaagcgttca cccggctact cgggcgggcg gtgaccgccc ccgagctggg ctggcccgac
    16861 cccgggccgg tcgcggtcaa cccgtgggac ggcgacccgg tcgcctgggt gacccgtctc
    16921 gggagggacg acatgctgaa caggcgcacc gtgctgaccg ccggcctgta cacgctggcc
    16981 gcgctgaacc tgccgcccac cccggcggcc gccgcgcggg cggggcagcc gcgccgcgcg
    17041 ggcggcggcg acgtcgaacg catccgcgcg atgaccgccc agttcgccga cgccgactcc
    17101 ctgttcggcg gcggccacgc gcgcaccgcc gtcgcgtcct acctggtggc ggaggtgacg
    17161 ccgctgctgc acggcacgac gggcgcggcc cgccccgccc tgttcaccgc cgcgtcccag
    17221 ctggcctacc tggccgggtt catggccaac gacgcgtgca tggccgggct ggcgcagcgg
    17281 tactacattc aggcggtccg gctggcagac gaggccgggg acccggtggc gaaggcgacg
    17341 gcactgcgcg gcctggcgtt gcaggccgtc gagatcggcc accccgaccg ggcggtgcac
    17401 ctggcggagg ccgccgcggc ggccctggac gacagctgcc cgccgcgggt gcgggcgtgg
    17461 atgaacggca tgcgggccaa cgcgtacgcg gcgggcggcg acacccgggc ggcgatcgcc
    17521 gccctcaccc aggcggaggg gcaggtggag cgggccgagt cgccgccgga gtcgcagtgg
    17581 accggggcgt accgccgcgc cagcctggag cacgacaccg gcaccaccct ggccgcactg
    17641 tccgacctgg ccaccgggga gcggcacatg gtggactcga tccgggtgcg gcgtggcggt
    17701 gagcgccgct cccgggtgct gatcacctcc cgtctggcgg ggatgcagct gcggcagcgg
    17761 cgcgtcgatg aggcggccgc caccgtgctg ggcatgcgcg ccgatctgcc gctggtgtcg
    17821 tcggcgcggg tcgccaagga gctgtccgcg ttgcgcgccg gctggaccgg tgcccggtcg
    17881 cccggctccc gggtggagga ggcggaccgg ctgatcgcct ccgtcacccg gtgacgggca
    17941 ggccggtccc cggggcggcc tagtcgcggc ggtggagctg gtagtcgccg cagcccgtgg
    18001 ggcggtggtg gcgggggagc ggaggtcacc ggcaggtcac ggcccggcga cacgacaccc
    18061 gtacggctgc gcgccgcagc ccggcggtga cagagtggcg cgagagcaac caggacataa
    18121 cctcgaaaac ctgttcgacc gtgtcctggc tgtgacataa aaagggcaca ctggtatagg
    18181 gatcgccgat gacccccaag gcgtctaaac gggtagaagg aactgggaga ccagcgggag
    18241 gaggcagcgg catggcacgc atcaaagacg tcgccgccta catcctcgcc aagtgcggcc
    18301 ccatgaccgc catgaagctg cagaagctct gctactacgc ctacggctac cacctggcgt
    18361 gggaaggccg ccccctgttc cgggcaccct tcgaggcgtg ggccaacggc cccgtcgccc
    18421 ccgccctgta cggcctgcac cgcggccggt tccaactgga cgccggcgac atccccggcg
    18481 accccggcgt cctcgacgac ggcgaacggg agtccgtcga cgttgtgctc gacaacctcg
    18541 gcaagctgtc cgcccacgac ctgtccgaga tgacgcaccg cgaagccccc tgggtcaacg
    18601 cccgcaagcg cgcgaacgtc ggcccgctgg agcgcagcag cgaaccactc gacgacgacg
    18661 agatctacga gttcttcgac gccctcgtgt ccgcggatgg gcagcagtaa gaagaaggtc
    18721 tccgcacccg ccaagaccgg taagggcaac aagcccttcg tcgcgtcgcg gtcgctgctg
    18781 ccgcgtgcgg agacctccga cagtcgcatc gcgtggcggt tctgccacgt cgaccacgcc
    18841 ggcccgtggg ggttcggcga cctcaccttc gcccagatta tggacaagct gcgggcgttc
    18901 gagtccatga cctgccgcga gatcttcgac cagggcgagg aacccggcaa gcactacgac
    18961 gtcgccgccc tgcccaacaa ggtcgcgatc gaccggctag aagccctcaa ccttggcgac
    19021 atgacgaaga tctcccgcct gcggctcggc ggcgccatcc gcctgtacgg cttcctggag
    19081 ggcaacgtgt tccacgtcgt gtggtgggac cccgaacacc aggtgtggcc ctccacccgg
    19141 cgctgacccc cagcccccac agcggggggt cagcaggccg cagcctccac cgactccgcc
    19201 agcacaaacg cgcggttcag cccggtgatg tgcagcagcc gggccagcac cccccgcgcc
    19261 ccggccagca ccaggcgtcc gccgcccgcc gcgcaccggt cccgcagcga cagcagcagc
    19321 cgcagactgg aggagtcgca gaacgtcaac gccgacacat ccaccaccgt gtgctgcccc
    19381 gcctgcacca cctcctcgaa cgccgccctc agcaggtccg aactggccgc gtccagctcc
    19441 ccgtccgcga cgagcacaac gcgcggcccg tccgggcggg tggtgatgcg gagatgattc
    19501 aacgcgctac ccgatcactg ggcgagacgt gaagcctcgg gggagaaatc gggggacacc
    19561 ccaggtgtac cacgcacggt gatctctccg ttaccccctt cggtgcaggg ccgaccgcca
    19621 gagatcgacg tgcgggcgat cggttgcgag gaaaacggcg ttgagggtgt tgactcaatt
    19681 ttgcaccacc ccttaaatca gaccgcaaga atctggccat acctcccgta tgggcggctt
    19741 tacgggagtc tggacgttgg tgggggcctg catcggcgcg gtcacaacgc tcctagcggt
    19801 ctggcttaag cacaagttcg agaggcaacg cttcaagctg ttttggcgcg tgatggaagt
    19861 cgtcccgatc gtgaccgacg agacgcgcga tcacctcacc ctgttccaca actcggtgcc
    19921 agtgaaggac ccgcacacgg tgaaattccg cctggacgct gaaggaccca acgacctaga
    19981 cgccgacgcg ttcaaacagc ccatcaaggc cgagatcggc gccaagatcc tggacgtcgt
    20041 gaaagaggag gccatcccaa gctcgcctcc tgcactgcct cgccattgga acggcaacac
    20101 gctgctgatt gaccccgggc acatcggtcg ccagcagcaa gtcacctaca cgctgctggt
    20161 cgaacagaag ccgccgcgac caaccaaaga caaagtcaca ggcagtctcg tcaacgtcga
    20221 tctactgcca tacccgaccg gcccctcccg aaagcgcaca ctgtttcaga gcgtttgcgt
    20281 gctcgtgggg gttgcgttat ccgtgggggc gtcatttagc gaattcttca cgggggcaaa
    20341 cagcatcact gtcggagtga cgatcatcgg ttttgttctc tttatcctcg cgttcccctg
    20401 gcgcatcgtc aaggggtagc ggcgccctca acaacgtgcc cagtgacgcc acgctcgccg
    20461 ccaccaccgc ccccgccagc gtcggtgtcg gagcaggaat ggccggtcgg gcacccgcgc
    20521 ccagccccgg cccgggatgt gcacccaggc ccggccggac cggtcgacca gccccgcctc
    20581 ccaccacccg ggcggcgggc tcaccgctcc gcctgcccgt cagccacgga cgccctccac
    20641 caccggcacc agccccgagc acgacgggcg ggacgccgcc cagcccaaca cctgctcggc
    20701 cgaggtccgc tcgccggcca cggccgggat cggcggcccc gccatcacca gcagctgtcc
    20761 ctcggccagc gcggcctcca cccagccggg cggcgcgtcc atccgctcga cctcgaccag
    20821 ggtggtgccg cgtcgggtga ccgacagcca cctcgcgcgg gtcagggtgc accgccaccc
    20881 gcggcccgcg tcctgcagca cgaacgaagg cccctcgacc cgggtgtacg gcagccccag
    20941 caccgacagc gcagcgggca gcacctccac cgccgggtcg ccgatcagcg gcgacacata
    21001 cagcagcgcc gacggaaccc ccggcaggtc ctcgacccac aggaacgggc gggcgtcgat
    21061 cggccccatc gtcacggccc cgccaccccc cgctgcccgc ccggccccgc cgcatccccg
    21121 ggcgcctcgg cggtgacctc gcacagcacc cgggcggcgt cgtggatgcc ccgcacctgc
    21181 tccggcggca gctcgcggag ccggtcccgc agccggtcca ggtcaccccg gaaggccagg
    21241 cccatcgcgc ccgacgcctg catggtgcgg tgcgtcacct ccatgctccg cccgatcgcg
    21301 ctgaccgcct gggcgaacgc cagcagcggg tccggcggcg ggtcgccgtc gcgttcccac
    21361 accagttcgc gggggctggt ccacaggtgc tccccgtggt cccaggcgat gttaaccgag
    21421 cagcagttcc ccgacacgtc ggagtcgtgc acgcggcccg cccccggcct accctccggc
    21481 cggggggcga cctcacccgc ccagtccagg tacaggtggc ggacgcgtcg gccgacgggc
    21541 agaacctgct tggcctcatc cagcgtgatc acaacgcggc ttcccttcgc ggggcgacgg
    21601 tgcagcgcat tacaccaccc gccgcggccc gcccgcctgc gtcttcgccg aagacacgga
    21661 cgcgagtgtg acggggcggc tacgctcggc cacgcaacca gccccctcgg cgatctcgac
    21721 gctccaacgc cgcgggggcc ggctacccgt atgacgcggc cccccggacg gtcacccacc
    21781 ggggacgcgc cgcgccgcac gcggggctcg ggcctcctgg ggttggcccg aggcctcccg
    21841 cgccccgtca gtccgggcgg cgcatcagct cgcggggagt gggcacgcct tcccggttca
    21901 ggtgctcggc cagctcctcg gtgtcgaaca ccccgtcggc gtacagcgcg tacacctcgc
    21961 gcaccacctc ggcctgggcc atatgcagtc cgcgctccat gccagcacgg taggccgccc
    22021 cccgcccggt gtgacacaag ttggcacttg ttggcagaag ttgacacccc gccggtgggc
    22081 tcacctgcgc cgcagcagcg cgagcagcct ccgcgcccac gcgggcggcg tgtacgcaag
    22141 gtcgcacacc acgccggacc gcagctggaa cgtcctggcg tacgtgaacg accggcccgc
    22201 cccggcgccg ctcacaggcc ctcccgctgc gcgtgcaggt ccagcacccg caccccaccg
    22261 gcggccgact ccagcgcgtc aaccgtctcc ccaaggtcgg cgtcatcggc gtcgacccgc
    22321 ccgaacaggt cccgcaccac ggggaccagc gcggtcagcc cctcggccag gtcgtgcacc
    22381 acctcggcga cgtccggggt gcgggccacg tcgaccgcgc ccagccgcac cgccgcggtg
    22441 cgcagcaacg ccgccgcggc ggcgccgctg tcgtcgccgg ccagccgggc cagcgtctcg
    22501 agctccaggc gctgctcctg gtcggcgacc gccgccagga cgcgggcgac caggtcgccc
    22561 tccgcgccgc gcggcgcggc gaccagcccg atcaggcacc gggcgaaccg ctcctccaag
    22621 gtcgcggcgc gcagccgcgc ctcgcgcagc gcgggtggca ccccgaaccc gggcggggcg
    22681 tcgccctccg cttgggccag gtcggcctgc gcggcctgca tctggcggcg cagcagcgac
    22741 agctccccgt cgtggaacca caagggtgcc gacccctcgg gcggccccgc caccaggtca
    22801 tcgtccatcg ggtgatcggt catggtcagt ccttccgtca gtcggcgggt ttgaacagct
    22861 gcgtgtcggg gtcccacacg aacagcccga cctcgatcag gtcgaagatt tcacgcttgt
    22921 cgacgccgta ccgttcggcg gcgatgtcct ggggccagcg gccccaccac atcgacggct
    22981 tgtcgtcgat gacgccgccg aacacctcgc acccgggcgg ctcgtggcag tcgtaccgct
    23041 gcccgccgca gtacgggcac cgcgccttgg cgcacccggg ccggtgcggc tcgttcatcg
    23101 cggcgtggca gccgccgcac aggctcgaca ggtcattggg cacggtcatc gaccggcgga
    23161 cgtaccgccc gtcggcgggc gggtcctcac ccaccggcct gctccccgcc gggggtgtcg
    23221 atcgcgaccg catgccgcca catcccgccc ggggtccgct cgtagtggcc gggctcgaag
    23281 ctgcccgcct gcagcacgat ctccagcacc aggcccagct caccccgcag ccggtcgtag
    23341 cggtccacgt cctcgtcgtc gtagccgccg tcggtgcggc cgtcgacgat ctccgccatg
    23401 tcggcgtaca cgtcgtcgct gtccccgaac gggtgcctgc ggtccaggct gggggccccg
    23461 acgtcgcggt gcccctccca cgcggtgttg gcgcggcgca gcagccggat gtgctcgggc
    23521 cgcacctcga actggtgggc gtcccgcagg ccccgccaca cgtcgtacgg gctccactcg
    23581 tcgtcggtgg tcatgcggtg ttgatccttc ccggccggga tcggcctacc agttaggggg
    23641 tcagcgggcg attgactgct ggcccgaatc cgggccgcgc ccgctcacct cagcccgcag
    23701 gggttggagg cgggacagcg cgagccgggg gtcggtgaac agcgacgggt tctcctgcag
    23761 gacctgcacc tgctcgggtg tgagctcccg caccaccggc accccgtcga ccttcacgat
    23821 caggatgttg ctgatcatga tgagtgcgtc cggggtggac tgcagtttgt ccagcaggtt
    23881 ggcgacggcc tcgccctgtg ccttggtgat ctgggactgc ggctcgccgt accagcgcgc
    23941 cttagccccg gctgtgaacg cgtcgccggc ctgatccagc cggtccggtt ccacctgccg
    24001 tttgaacgcg gccgttatta cctgccatac ggacccgcga atgggagggc tgctgcggac
    24061 tggggccagg ccgaacgcct ccatggcgtc gtcgagtgcc tcgcgcacgt cgttgtatgc
    24121 gtcgtcgttg gagacgtaca gcacaatg
//
