LOCUS       NZ_VYTZ01000002        22877 bp    DNA     linear   CON 20-NOV-2024
DEFINITION  Microbispora cellulosiformans strain Gxj-6 Scaffold2, whole genome
            shotgun sequence.
ACCESSION   NZ_VYTZ01000002
VERSION     NZ_VYTZ01000002.1
KEYWORDS    WGS; RefSeq.
SOURCE      Microbispora cellulosiformans
  ORGANISM  Microbispora cellulosiformans
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Streptosporangiales; Streptosporangiaceae; Microbispora.
REFERENCE   1  (bases 1 to 858968)
  AUTHORS   Gong,X.
  TITLE     Screening of Novel Bioactive Compounds from Soil-Associated
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 858968)
  AUTHORS   Gong,X.
  TITLE     Direct Submission
  JOURNAL   Submitted (20-SEP-2019) College of Land and Environment, Shenyang
            Agricultural University, No. 120, Dongling Road, Shenhe District,
            Shenyang, Liao Ning 110866, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: SOAPdenovo v. 2.04 OR JUL-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 400x
            Sequencing Technology             :: Illumina HiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008728085.1-RS_2024_11_18
            Annotation Date                   :: 11/18/2024 02:05:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,471
            CDSs (total)                      :: 7,401
            Genes (coding)                    :: 7,312
            CDSs (with protein)               :: 7,312
            Genes (RNA)                       :: 70
            rRNAs                             :: 5, 2, 1 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 1 (5S, 16S)
            partial rRNAs                     :: 3, 1, 1 (5S, 16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 89
            CDSs (without protein)            :: 89
            Pseudo Genes (ambiguous residues) :: 0 of 89
            Pseudo Genes (frameshifted)       :: 7 of 89
            Pseudo Genes (incomplete)         :: 80 of 89
            Pseudo Genes (internal stop)      :: 8 of 89
            Pseudo Genes (multiple problems)  :: 6 of 89
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 09:06:26
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 515289
            Orig. end                         :: 538166
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VYTZ01000002.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22877
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-ii"
                     /region_number="1"
                     /rules="cds(LANC_like and DUF4135)"
                     /tool="antismash"
     cand_cluster    1..22877
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="cds(LANC_like and DUF4135)"
                     /kind="single"
                     /product="lanthipeptide-class-ii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22877
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12877](+)"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12877
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="cds(LANC_like and DUF4135)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-ii"
                     /protocluster_number="1"
     misc_feature    complement(31..46)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 20.25"
                     /tool="antismash"
     misc_feature    1647..1660
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.32"
                     /tool="antismash"
     gene            1929..2939
                     /locus_tag="F5972_RS06295"
                     /old_locus_tag="F5972_06295"
     CDS             1929..2939
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013132551.1"
                     /locus_tag="F5972_RS06295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06295"
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="WP_150931979.1"
                     /transl_table=11
                     /translation="MKILVIGGSVFLGRAIVEEALRRGHEVTTFNRGRSGTDLPGVEAV
                     RGDREVTGDLRRLADGRQWDAVVDVCGFVPRVVLESVRALSGHAPHYTFISSISAYPDW
                     PDKTGLDETFPIHECPPDADAEFGDYGVLKAGCERAVEEHFDGAALVVQPGLILGPHEN
                     VGRLPWWLHRISKGGRVLAPGDPALPIQLIDARDIAAFTLDQAAAGTTGRYMTGGVPGE
                     ATFGSWLGDCVQVTGSGAELVWADDDFLTAQGVEPWTELPLWYPGADGLGVWTHSSAKA
                     VAAGLTCRPLRETVRDTWEWLKDIPEERRSFRGVRVGSGIDPDKERRVLAAWDAR"
     gene            3060..3620
                     /locus_tag="F5972_RS06300"
                     /old_locus_tag="F5972_06300"
     CDS             3060..3620
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014505.5"
                     /locus_tag="F5972_RS06300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06300"
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="WP_150931981.1"
                     /transl_table=11
                     /translation="MLWVALLIVAVLIVLAALVASGRVRQASRGPARGTSRRRPAPRPS
                     GGTARPSGGARPGARPSSRTARGGTRTGAAAGEGTGPRPGEIWWADVPYEDGPGHKVRP
                     CVVLRTYRGGAEVLKITSQDRSDRSDHVEIPTRTWDPGADHNSFLDLTGPVRVPSASFD
                     DRAGTLDPRVWRQVCRLHEISPN"
     gene            3725..4009
                     /locus_tag="F5972_RS06305"
                     /old_locus_tag="F5972_06305"
     CDS             3725..4009
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012887056.1"
                     /locus_tag="F5972_RS06305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06305"
                     /product="YiaA/YiaB family inner membrane protein"
                     /protein_id="WP_150931982.1"
                     /transl_table=11
                     /translation="MTKPVKSTTTTAFYLQAVISFVISLAGLAAGILYLPVTTWVRSFL
                     ALGLMYVVTSTFTLAKCVRDRQEEATVVSRVDQARLDKLLAEHDPFRAD"
     CDS             complement(4161..4343)
                     /gene="allorf_519450_519632"
                     /locus_tag="allorf_519450_519632"
                     /protein_id="allorf_519450_519632"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MATGRRRGRASRRDAGAGPRAWSGPGTRRDETGARCFRRHRVTLS
                     IELGDSGRGKSISWG"
     CDS_motif       complement(4242..4343)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence:
                     MATGRRRGRASRRDAGAGPRAWSGPGTRRDETGA"
                     /locus_tag="allorf_519450_519632_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(4161..4241)
                     /prepeptide="core"
                     /locus_tag="allorf_519450_519632_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-4.50"
                     /molecular_weight="2884.3"
                     /monoisotopic_mass="2882.6"
                     /core_sequence="RCFRRHRVTLSIELGDSGRGKSISWG"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MATGRRRGRASRRDAGAGPRAWSGPGTRRDETGA"
                     /leader_location="[4241:4343](-)"
                     /alternative_weights="2902.3"
                     /alternative_weights="2920.3"
                     /alternative_weights="2938.3"
                     /alternative_weights="2956.3"
     gene            4404..5384
                     /locus_tag="F5972_RS06310"
                     /old_locus_tag="F5972_06310"
     CDS             4404..5384
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF019352.5"
                     /locus_tag="F5972_RS06310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06310"
                     /product="multicopper oxidase domain-containing protein"
                     /protein_id="WP_150931985.1"
                     /transl_table=11
                     /translation="MTRSVFSRRAFTTAATAAAIAPLVVSAQADAAPVGRTAPPPADPG
                     KPRRITLYVENLPNGEMGYGLAPGKATIPGPLIEMVEGETLEVELVNNADVTASLHVHG
                     VDYETSSDGTRMNDSVVAPGARRVYVWRTHAPGRRPGGTIEPGSAGYWHYHDHVVGTDH
                     GTGGIKKGLYGPLVVRRKGDTLPDKTFTVVFNDVKINNLAAGPHFLAKIGERVEFIVIT
                     HGSVFHTFHIHGHRWADNRTGLLESPQDPSRIIDTKTTGPAESFGFQVIAGERVGPGMW
                     MYHCHVQSHSDMGMAGVFMVSDQNGNVPGGHDMGGGSGGGMDMSH"
     gene            5558..6307
                     /locus_tag="F5972_RS06315"
                     /old_locus_tag="F5972_06315"
     CDS             5558..6307
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS06315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_06315"
                     /product="hypothetical protein"
                     /protein_id="WP_150931987.1"
                     /transl_table=11
                     /translation="MTGDHLRAGQAATASTGAQPALDYYVITPEAGAGAVRAEGLVVEE
                     FVFTGDHRTIGLNTATWSTDDRAWQSSAVFGRAMREDPRLRARVVAVGRTDAETTYRRL
                     GGGALRGEAALRECFRDTLALPDSAPLRLGPEEGSDGFPDPRIYRVLFAGDLRPPGLAR
                     LAPEVVTLAEDAGDSRTRIAGRGGLRTARDVFTWELRRIGPGVACCVDLTARLGTTSDD
                     ALRPLLRRLTTAIRHTGPIPVTIERFS"
     misc_feature    complement(6346..6362)
                     /note="TFBS match to GnfM, Regulator of nitrogen-fixation
                     genes, confidence: weak, score: 20.47"
                     /tool="antismash"
     misc_feature    6346..6362
                     /note="TFBS match to NtrC, Nitrogen regulatory protein C,
                     confidence: medium, score: 23.25"
                     /tool="antismash"
     misc_feature    complement(6380..6391)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 16.07"
                     /tool="antismash"
     gene            6572..6853
                     /locus_tag="F5972_RS06320"
                     /old_locus_tag="F5972_06320"
     CDS             6572..6853
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS06320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_06320"
                     /product="hypothetical protein"
                     /protein_id="WP_150931989.1"
                     /transl_table=11
                     /translation="MGAVVAILGLGGVVEFKGEVAGAKAETTSVGLAVLVVGALLAGIV
                     AVKLPAQVTVLGDGGRSGFTEWFSEFGVRLCAVLVAAGVVLLIISLFA"
     gene            6883..7707
                     /locus_tag="F5972_RS06325"
                     /old_locus_tag="F5972_06325"
     CDS             6883..7707
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S8"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012311.5"
                     /locus_tag="F5972_RS06325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06325"
                     /product="S8 family serine peptidase"
                     /protein_id="WP_191909965.1"
                     /sec_met_domain="Peptidase_S8 (E-value: 1.5e-07, bitscore:
                     26.4, seeds: 43, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDERIVEIAGDEGSSPGRYMRYVFDDDTGTYLRPADTEQMLAFRE
                     RGVKTAYMQAQAGAGFDADAFEAAWPGIWRELTRKRQEPTPEYFAIVDTGLLSRHPLLR
                     GLIVDGTNLTTEPDGEDTNGHGTMVALILADGLTRRPRLLNVKVADGNGHATPRDLVKG
                     IEWVRDFARKTSSPVCVNISLGCYSRRWGLVACDGTCDLCEAAVTAAGDVRMMTVAAGN
                     EPNKTTCPAMAGLRGRAGNIFAVAQLGWDRSGVGTVAMPVGMQWVPCEETDE"
     misc_feature    7585..7587
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(7861..8478)
                     /locus_tag="F5972_RS06330"
                     /old_locus_tag="F5972_06330"
     CDS             complement(7861..8478)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF039462.4"
                     /locus_tag="F5972_RS06330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06330"
                     /product="DUF6461 domain-containing protein"
                     /protein_id="WP_191909966.1"
                     /transl_table=11
                     /translation="MPPVTADDYSWQNDWEDIYTVTFVRGHDERETLRRFGIAQADMRP
                     YDWEGIWERVEETDGESDLVVVTHVNGWTLAFEACGWEGNRPETLRELSRGGEAVSVMR
                     HDYAASHHFAHAVEGELRTAFRPDWPRERWGARPDALNADLRELGLTPSGPQEESRYRR
                     ETVAPALALASRLSGVLFHRDMVESDALLGGVITSPVPDDPR"
     misc_feature    8534..8549
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 18.08"
                     /tool="antismash"
     misc_feature    complement(9076..9089)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.08"
                     /tool="antismash"
     misc_feature    complement(9082..9091)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.08"
                     /tool="antismash"
     CDS             9358..9492
                     /gene="allorf_524647_524781"
                     /locus_tag="allorf_524647_524781"
                     /protein_id="allorf_524647_524781"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MEGGRSRSRVPDIPSASRQAPSQSTAAFAISAECRQVYVSLAMY"
     CDS_motif       9358..9444
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MEGGRSRSRVPDIPSASRQAPSQSTAAFA"
                     /locus_tag="allorf_524647_524781_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9445..9492
                     /prepeptide="core"
                     /locus_tag="allorf_524647_524781_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.30"
                     /molecular_weight="1697.0"
                     /monoisotopic_mass="1695.8"
                     /core_sequence="ISAECRQVYVSLAMY"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MEGGRSRSRVPDIPSASRQAPSQSTAAFA"
                     /leader_location="[9357:9444](+)"
                     /alternative_weights="1715.0"
     misc_feature    9490..9499
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.26"
                     /tool="antismash"
     gene            9550..9741
                     /locus_tag="F5972_RS06335"
                     /old_locus_tag="F5972_06335"
     CDS             9550..9741
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.4"
                     /locus_tag="F5972_RS06335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06335"
                     /product="DUF6229 family protein"
                     /protein_id="WP_208758842.1"
                     /transl_table=11
                     /translation="MPVTLDRSEEIVSAWRSGADVEGWDSPAGPLFIGEYAESEITLTA
                     LDTRRPSSCTGANTIPCC"
     CDS_motif       9550..9636
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPVTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /locus_tag="F5972_RS06335_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9637..9741
                     /prepeptide="core"
                     /locus_tag="F5972_RS06335_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="3486.9"
                     /monoisotopic_mass="3484.7"
                     /core_sequence="PLFIGEYAESEITLTALDTRRPSSCTGANTIPCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPVTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /leader_location="[9549:9636](+)"
                     /alternative_weights="3504.9"
                     /alternative_weights="3523.0"
                     /alternative_weights="3541.0"
                     /alternative_weights="3559.0"
                     /alternative_weights="3577.0"
     gene            9796..9981
                     /locus_tag="F5972_RS06340"
                     /old_locus_tag="F5972_06340"
     CDS             9796..9981
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF040361.4"
                     /locus_tag="F5972_RS06340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06340"
                     /product="DUF6229 family protein"
                     /protein_id="WP_111701617.1"
                     /transl_table=11
                     /translation="MPLTLDRSEEIVSAWRSGADVEGWDSPAGPLFIGEYAESEITLTA
                     LDTRLASSCTCSRFCC"
     CDS_motif       9796..9882
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPLTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /locus_tag="F5972_RS06340_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       9883..9981
                     /prepeptide="core"
                     /locus_tag="F5972_RS06340_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-5.00"
                     /molecular_weight="3357.8"
                     /monoisotopic_mass="3355.6"
                     /core_sequence="PLFIGEYAESEITLTALDTRLASSCTCSRFCC"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPLTLDRSEEIVSAWRSGADVEGWDSPAG"
                     /leader_location="[9795:9882](+)"
                     /alternative_weights="3375.8"
                     /alternative_weights="3393.9"
                     /alternative_weights="3411.9"
                     /alternative_weights="3429.9"
     gene            10001..12877
                     /locus_tag="F5972_RS06345"
                     /old_locus_tag="F5972_06345"
     CDS             10001..12877
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: LANC_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-ii: DUF4135"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:TIGR03897.1"
                     /locus_tag="F5972_RS06345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06345"
                     /product="type 2 lanthipeptide synthetase LanM family
                     protein"
                     /protein_id="WP_150931995.1"
                     /sec_met_domain="DUF4135 (E-value: 2.7e-79, bitscore:
                     262.5, seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.9e-40, bitscore:
                     132.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAGDFDPSLDFLTAPALAGLSATLGSIPGLTEAEARLICRRTAEA
                     LEETVRLKVNRVLLLELNAARISGRLTAETPQLRWQEWKATAATPEFWLSLTGHYPTML
                     SRLGTLIDNRCAAAVELARRFAADRAALTTLPGGLRGELVGVDFGAGDSHRGGHSVAVL
                     HGSQGKVVYKPRSLAVDEALARLIDRLAPQLPAGSRIRVPDVLIRQGYGWAEHIQHRYC
                     ADETELRSFYRGVGHWLALMRLIGGSDLHMENLIAAGPAPVVVDCETLFTPHVPAKPSG
                     YGNAVDQATDLLSGSVLRTGLLPGRGVSLAWRGVDMSAVGGLPGQQPYTQVPVVVDAGT
                     DVARLGMERVELGAVSNHPSPDPILVHYWDLVLSGFTELVEHLDMLDRRGELAGLLTDF
                     ADRQIRVVLRATEAYAELARMLWHPASLHDEPTARGKAAGLLAQHAENLPGAPSNPEVI
                     DAEVAELLVGDIPFFATTPARGRLDGPGGTSYGDEQDLIADALRRWRDRDAALDREVIR
                     SALVSAYLNEGWMPANKRMTVPLIRHQDLERRRRRITAGIARSMLDTAVRGDDGTVTWT
                     APVLTSDGWFVQSLSPDVYGGAYGVAITLAAYVSETGQGRADEVPGLDGLLADLLHTIR
                     LAEERDAEARRTGPRRRPATPGGYVGIGSQIWSWLLLRRLGTVGSEEAVARAGALAGQL
                     PEAVAADGVYDLLTGMAGAIVPLLRLSEQTGDQQWSTQADRIGERLLSLAHIDDRGARW
                     PSTAFPQGLGGVSHGATGIAWALARLADSATAGAADFRALADRAFLYEESLYDPAEKGW
                     RDLRETDDHRVTSSAWCHGAAGIGLVAADRLAREGDPRWADVLRRAAASSWSRGIGWNH
                     TLCHGDLGTWEIVRRAIDVGVGPEELTPEYLAAYMIGSMDEHGPVSGLSRDAFSPGLMP
                     GVGGMLYQLLRLHPDTSLPSILLPDPEN"
     misc_feature    12284..12286
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(13013..13630)
                     /locus_tag="F5972_RS06350"
                     /old_locus_tag="F5972_06350"
     CDS             complement(13013..13630)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS06350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_06350"
                     /product="hypothetical protein"
                     /protein_id="WP_150931998.1"
                     /transl_table=11
                     /translation="MSVSEPTLETVRAYLLAQANSALRRPGMHGGEVAVRLYLDAVAVA
                     CGTEQAWAADMDNLRERGGSNGVGVTGALATVLGDGTEDAMASVYADLAYSRNWLHLDH
                     RLPPDDYNAMRDGIAATCRTGASWSHLRERFGEPSILFGGTSPHYPKTLGYASDRPQDP
                     LICFHLWNDLGIHPEPVLVAVRRAHPSAAFRDAFTFASVRRP"
     misc_feature    complement(13644..13659)
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.5"
                     /tool="antismash"
     gene            13752..14408
                     /locus_tag="F5972_RS06355"
                     /old_locus_tag="F5972_06355"
     CDS             13752..14408
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018654536.1"
                     /locus_tag="F5972_RS06355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06355"
                     /product="maleylpyruvate isomerase N-terminal
                     domain-containing protein"
                     /protein_id="WP_150932626.1"
                     /transl_table=11
                     /translation="MDLFTRSWTALRRAVAELPDEAFAQRSGCVGWLVRDLVCHLVLDA
                     QDVLITLATPTETEPTRDEVTYWEVSTTPPAGDDPLDALVVRLAAAYEEPWLLKFHLDD
                     VGSAAGRAAELADPDLRVGTRGEVLTVAAYLSVYVMEWTLHHLDLVAYLADVPEPPVEG
                     LARSREMLERIAGSAFPPSFSDKDALLVGTGRRAVTDAERNELGELATRIPLVLG"
     gene            14772..15254
                     /locus_tag="F5972_RS06360"
                     /old_locus_tag="F5972_06360"
     CDS             14772..15254
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS06360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_06360"
                     /product="hypothetical protein"
                     /protein_id="WP_150932000.1"
                     /transl_table=11
                     /translation="MSRLIDSLTDVITVEYRQVMIMDLDGANGVPEGAEDLWELSDRAN
                     VTNWFIATANVGIITSEADDWHRVEVTLELWDGEPPADHALWARSETVELYSSSGKLRM
                     VGPFGNSSGKLIDLRQKARNWLVRANVRPSPGARYPEEQPPEGLETYRLQFWPALP"
     gene            complement(15423..16001)
                     /locus_tag="F5972_RS06365"
                     /old_locus_tag="F5972_06365"
     CDS             complement(15423..16001)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS06365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_06365"
                     /product="hypothetical protein"
                     /protein_id="WP_150932002.1"
                     /transl_table=11
                     /translation="MSAKFGKSLRSASWVFFSLAVAMTGAAIAPPGSRLLVAVAIAAVI
                     SISSRATSANRQTELKWRRARRGSPLKSLTPGWTILPILAALVVLLAIFMIGRGDYVGA
                     PPTTSPDPRATVTVTVTAPPVASPAAHAADRSSPSEVSLSVLLGVAAAVFAAIGAMMQG
                     VGALMQAVSARRTVNNGKEDTSQPFGRYL"
     gene            16236..16553
                     /locus_tag="F5972_RS06370"
                     /old_locus_tag="F5972_06370"
     CDS             16236..16553
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF042633.3"
                     /locus_tag="F5972_RS06370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06370"
                     /product="replication initiator"
                     /protein_id="WP_318527520.1"
                     /transl_table=11
                     /translation="MRLRGWTHMLGFLGHFSTKSGSYSTTLGKLRDARRSFRARQAREH
                     GHDALTGTPADDSTLVVGSWRYAGQGYTHPADLYVAQFIREEREERRRSHWPARASGAA
                     A"
     gene            16550..16750
                     /locus_tag="F5972_RS06375"
                     /old_locus_tag="F5972_06375"
     CDS             16550..16750
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017581651.1"
                     /locus_tag="F5972_RS06375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06375"
                     /product="AlpA family transcriptional regulator"
                     /protein_id="WP_150932006.1"
                     /transl_table=11
                     /translation="MTRREATLAADDTRMWSIEEVSRFLGIPVGTLYQWRHRRVGPRGR
                     RIGKYLRYLPEDVYAWVREQE"
     gene            16747..17253
                     /locus_tag="F5972_RS06380"
                     /old_locus_tag="F5972_06380"
     CDS             16747..17253
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF026010.5"
                     /locus_tag="F5972_RS06380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06380"
                     /product="N-terminal phage integrase SAM-like
                     domain-containing protein"
                     /protein_id="WP_191909967.1"
                     /transl_table=11
                     /translation="MTVTDRWHKSHPKKGELVCPEHKRVPTREHGRGDRWLVRYRDEKG
                     LQLKRSFDRKADADRFDAARKADTARGDWIDPKLGQTKFGDYAPEWLAARLHKPTTEET
                     YRNHLRKHIYPAFDRAPLASIRPTTVQQVGQGPAVQGARASHDRDRLHDLCEHHARGRP
                     RRSDQ"
     gene            17219..17920
                     /locus_tag="F5972_RS06385"
                     /old_locus_tag="F5972_06385"
     CDS             17219..17920
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1077: phage integrase
                     family protein"
                     /gene_kind="other"
                     /inference="COORDINATES: protein motif:HMM:NF012798.5"
                     /locus_tag="F5972_RS06385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06385"
                     /product="site-specific integrase"
                     /protein_id="WP_150932010.1"
                     /transl_table=11
                     /translation="MRGAVRDGLISKTPCRDIRLPHADKTVIRLLAPEQVMRLSRAMPP
                     KYGPLVLLGAAAGLRQGEAFGLSVDRVRFADQMISVDRQVVIVDRRPTLATPKSPASVR
                     EVPMPVFLAETLEKHIADHSPADLLFSTSRDNLMRRDYFNARIWKPAIKAATLLPDTTF
                     HDLRHTFASTALAEGVPISEVSRWLGHESITTTVDLYGHLVPEASERARTALDSAFRSA
                     LDVPPMCPEGE"
     ncRNA           complement(17954..18345)
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="F5972_RS06390"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="F5972_06390"
                     /product="RNase P RNA component class A"
     gene            complement(17954..18345)
                     /gene="rnpB"
                     /locus_tag="F5972_RS06390"
                     /old_locus_tag="F5972_06390"
     CDS             complement(18183..18392)
                     /gene="allorf_533472_533681"
                     /locus_tag="allorf_533472_533681"
                     /protein_id="allorf_533472_533681"
                     /tool="antismash"
                     /transl_table=1
                     /translation="MPGNGAGADRLTFTVDEPAGRPRQGLAPCRGRSGLHRAGWSVTPT
                     RGDPRDSATENRPPLLGGKGETVV"
     CDS_motif       complement(18333..18392)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MPGNGAGADRLTFTVDEPAG"
                     /locus_tag="allorf_533472_533681_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(18183..18332)
                     /prepeptide="core"
                     /locus_tag="allorf_533472_533681_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class II"
                     /score="-6.10"
                     /molecular_weight="5094.7"
                     /monoisotopic_mass="5091.7"
                     /core_sequence="RPRQGLAPCRGRSGLHRAGWSVTPTRGDPRDSATENRPPLLGG
                     KGETVV"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MPGNGAGADRLTFTVDEPAG"
                     /leader_location="[18332:18392](-)"
                     /alternative_weights="5112.7"
                     /alternative_weights="5130.7"
                     /alternative_weights="5148.7"
                     /alternative_weights="5166.7"
                     /alternative_weights="5184.8"
                     /alternative_weights="5202.8"
     misc_feature    18232..18244
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            18538..19524
                     /locus_tag="F5972_RS06395"
                     /old_locus_tag="F5972_06395"
     CDS             18538..19524
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017585703.1"
                     /locus_tag="F5972_RS06395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06395"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_150932011.1"
                     /transl_table=11
                     /translation="MIEIRGLTKRYGDVTAVDGLSFDVRPGVVTGFLGPNGAGKTSTMR
                     MVLGLDRPTSGSATIGGRRYADMPTPLREVGALLDAHAVHPYRSAVNHLLTLARSNGIG
                     RGRVEEVLGLVGLADVAGRRPAGFSLGMKQRLGIAAALLGDPGVVLLDEPVNGLDPEGI
                     RWIRGLTRDLASEGRTILLSSHLMSEMALTADHLVVVGRGRLLADTGLDAFVRSAARET
                     VVVRTPGARRLATLLEEAGATVRHGAGDELLVTGMSSAAVGDVAGAHGIVLHELTPRRA
                     SLEEAYLELTGDSADFASAAARPAARSETEAGAATTTASMTTSGAAR"
     gene            19521..20294
                     /locus_tag="F5972_RS06400"
                     /old_locus_tag="F5972_06400"
     CDS             19521..20294
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F5972_RS06400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="F5972_06400"
                     /product="hypothetical protein"
                     /protein_id="WP_150932013.1"
                     /transl_table=11
                     /translation="MTAYDILRSEWGKFRSIRATLGCLAGALATTAAYGYLFGLSSARQ
                     YLAGSAADRAAFDPTETGFRALVLAGVLVSAVGVLAVTSEYASGTMRVSVAAVPRRSLL
                     LGGKAAVVAVVALVAGPPMALVSFTLSQISLAARNVPSAGLGDPGVLAAVAGAGLFTGL
                     VGLYGVALGFLLRRSAGAVSLGTFLLILPGMAALFPDAIAEWIVVWWPSAAGARVFAVH
                     PGPDGLAPLAGIGVLAATVLALLCAAAAVFRTRDV"
     gene            20355..21065
                     /locus_tag="F5972_RS06405"
                     /old_locus_tag="F5972_06405"
     CDS             20355..21065
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012850957.1"
                     /locus_tag="F5972_RS06405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06405"
                     /product="response regulator transcription factor"
                     /protein_id="WP_150932015.1"
                     /transl_table=11
                     /translation="MDGRRLLVVDDEPVVRELLAATLRFAGYTVTSAATGSQALEAAGA
                     EPPDLVLLDVMLPDMDGFEVIRRLRDRPRPLSGDRPGQVPVLFLTARDTTQDKINGLRL
                     GGDDYVTKPFDLEELLARIEAVLRRAGAAPEDRTLRVADLELDPDGHQVTRAGVPVRLS
                     PTEFRLLHYLIVNAGRVVSKAQILEHVWRYDFAGDTSIVDTYVSYVRRKIDKAGPKLIH
                     TMHGVGYVLRGPRS"
     gene            21062..22711
                     /locus_tag="F5972_RS06410"
                     /old_locus_tag="F5972_06410"
     CDS             21062..22711
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF014567.5"
                     /locus_tag="F5972_RS06410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="F5972_06410"
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="WP_225311211.1"
                     /transl_table=11
                     /translation="MIRRTARGRSLSLRGRLLLITLALLAAGLTVSGAVAVATLRAHLI
                     ERVDLQLGPMATLLSRVPALMVTAPLAGQNRVPLSALPGMDLIDQVYLAYLRADGTVGQ
                     EGGPWLRGRGPELPRLDAAAVRRLGGRPFDARDDHGAAWRVVAVPLAAPGTTPPRPVAS
                     GQAPDEPAAGHAAGSAAQGATTEGDAAEGGTVVVAASLGGVRSTVGRLTLVCAATAAAL
                     LTSLAVIGWFAVRRGLRPLRAIERTAAAIAAGDLSRRVPVPAAPHTEVGRLAAALNTML
                     AQLEAAFAGRERSQARMRRFVADASHELRTPLFGIKGFAELHRMGGLPDVDHTLGRIES
                     EAVRLVRLVEDLLLLARLDEGEDALPMDLAPMDLRTLAADALHDLRALDPGRTVTLTGP
                     DGGPAGAAPVRGDEARLRQVVSNLVGNAVAHTPPGTPVRIGVGTVRSSAGGPEGVLVIA
                     DEGPGLPPEEAERVFDRFYRVDGSRSRGGAGGAGLGLAIVRSIVAAHGGRVELRTAPGA
                     GAAFRVALPIHPASPPASNGPASPPVGPRPAS"
ORIGIN
        1 gctccgcgct ggggaacgtt ctcgaactgc ccgcccagat cgtcaacaac cacacgcacg
       61 ccgtgctgat cggggtgctg acgatcgcgg tcctgctggt gtggggccgg atcccccggc
      121 tgcgtgccgt gcccgcccca ctggcggcgc tggtgatcgc gacgctgacg gcgggggtcg
      181 cgggctggga cctgacgaag gtcgacctcg gcggcgggtt ctcctccgtc cagacgccgc
      241 tcgcgccgca gggcgactgg cacgcgatcg ccggggccgt cctgctcgtc gccctcctgt
      301 cgggggtgga gtcgctgctg accgccgtgt cgtccaaccg cctgcacgac ggcccccgcg
      361 ccgacctcga ccgcgagctc accgcgcagg gcgtgggaaa cgtggtgtcc ggcgtgctcg
      421 gcggcctgcc ggtggcgggg gtcgtcgtcc gtacgaccac gaacgcgcgg gcgggcgccc
      481 gcagccgctg gtccacggtc ctgcacggcg ggtgggtgct gctgttcacc acggccttcg
      541 cctggatgat cgcgctgatc cccctggagg cgctcgcggc gctgctgctg ttcatcggcg
      601 tgcagatggt caacctcggg cacgtgcgga acctgcgcaa ccaccgcgag gtgccggtgt
      661 acgtcgtgac gatggccggg gtcgtgctga tcgggctcgc cgagggcgtg gcgatcggcc
      721 tcgcgctggc cgccctgctc gccctgcgcc ggctcgcgtg ggtctcggtc gacgtgcgcc
      781 aggacggcga gcgccgctgg cgggtcgtcg tcaccggatc gctgacgttc ctcggcgtgc
      841 cccggctgac cgaggcgctg cgcgccatcc cggcggggtc ggcggtggag ctcgacctgc
      901 acctcgactt catggacaac gccgccttcg tggcgctgca cgactggcgg ctggagcacg
      961 aacgcgccgg cggcgaggtc gacgtggacg agacgcacgg cgagtggtac tccgccgcga
     1021 tcaacggagc ccggctcttc cccgcgagga tcccgccccg gcacgaccgc tggtggctgc
     1081 cctgggccta ccggcgcccc gatggcgcgc actcgtacgg gtccttcgag gtgatcgagg
     1141 cggacggcgg gagcgccgcg ggcgacggcg acgccgtgat ctgcgagccg cagggcgtgc
     1201 ccgacctcct gaagggaacg cgggagttcc agcgcaggac ggcgccgatg gcccgtcccc
     1261 tgttcacccg gatggcccgc aagcagtcgc cgtcgcacct gttcatcacc tgcgccgact
     1321 cgcggatcgt gcccaacatc atcaccgcga gcggccccgg cgacctgttc acggtgcgca
     1381 acatcggcaa cctcgtgccg agggcgggcg cggtcccgcc ggacgactcg atggcggcgg
     1441 cgatcgagta cgccgtgaac gtgctggagg tccgcacgat caccgtctgc gggcactccg
     1501 ggtgcggcgc gatggccgcc ctgctcggcg agctgcccga cctgccggcg ctgcgcgcct
     1561 ggctgcggca cggacggcag agcctggccc ggttcgtcgc cgccgggccc gggcaggacg
     1621 ccgacgacgc cgggccactc gaccggctgt gccggatcaa cgtcatccag cagctcgaca
     1681 acctgcggac ccaccccctc gtggacgcgc gcgtacgggc gggcaggctg gagctcacgg
     1741 gcctgtactt cgacatcggc gcggcccggg tgcacgccct ggagcaggag cgcttcaccc
     1801 cggtcccgga gctgcgcacc accggctgag acgcaccggc cgtcaatccg cttgcgctct
     1861 cagcggacga tgtccgccga tcgtgaaacc gggcggacgc cgcgcgccgc agcgccaagg
     1921 atgaccgtat gaagattctg gtcatcggtg gttcggtgtt cctgggccgg gccatcgtgg
     1981 aggaggcgct ccggcgcggt cacgaggtca cgacgttcaa ccggggcagg agcgggacgg
     2041 acctgccggg tgtggaggcg gtgcgcggcg accgcgaggt caccggcgac ctgcggcggc
     2101 tcgccgacgg caggcagtgg gacgcggtcg tcgacgtctg cgggttcgtc ccccgcgtcg
     2161 tcctggagtc ggtgcgggcg ctgtccgggc acgccccgca ctacacgttc atctccagca
     2221 tctcggcgta tccggactgg cccgacaaga cgggtctcga cgagaccttc cccatccacg
     2281 agtgtccccc ggacgcggac gccgagttcg gcgactacgg cgtgctcaag gccggctgcg
     2341 aacgcgcggt cgaggagcac ttcgacggcg ccgccctggt cgtccagccc ggcctcatcc
     2401 tcggcccgca cgagaacgtc ggccggctgc cctggtggct ccaccgcatc tccaagggcg
     2461 gccgggtgct cgcgcccggc gacccggcgc tgccgatcca gctcatcgac gcccgcgaca
     2521 tcgcggcgtt cacgctcgac caggcggccg cgggcacgac gggccgctac atgacgggcg
     2581 gggtgcccgg cgaggccacg ttcggaagct ggctcggcga ctgcgtgcag gtcaccggct
     2641 ccggcgcgga gctcgtctgg gccgacgacg acttcctgac cgctcagggc gtggagccgt
     2701 ggaccgagct tccgctgtgg tacccgggcg cggacggtct cggcgtgtgg acccactcct
     2761 ccgccaaggc cgtcgccgcc ggtctcacct gccgcccgtt gcgcgagacg gtgcgcgaca
     2821 cctgggagtg gctgaaggac atcccggagg agcggcgcag cttccgcggc gtacgggtgg
     2881 gcagcggcat cgaccccgac aaggagcgcc gcgtgctcgc cgcctgggac gcccgctgac
     2941 gcgctccccg gccgtcgggt ggtccgctca ctgaaggggc atcacggacg accacggcca
     3001 catcgggcgc aggggtcaag gggtctcccg ggacgcggct gggccttagg ctgtcgggca
     3061 tgctctgggt ggctcttctg atcgtggccg tactgatcgt gctcgccgcg ctggtcgcgt
     3121 ccggacgtgt ccgccaggcg tcccgcgggc ccgcccgcgg gacgtcgcgc cgccggcccg
     3181 caccgcgccc ctcgggcgga acggcgcggc cgtcaggggg cgcccggccc ggtgcccggc
     3241 cctcctcccg tacggcccgt ggcggaaccc ggacgggcgc cgccgccggc gagggcaccg
     3301 gcccgcggcc gggtgagatc tggtgggccg acgtgccgta cgaggacggg cccgggcaca
     3361 aggtgcgtcc ctgcgtggtg ctcaggacgt accgcggcgg cgcggaggtc ctgaagatca
     3421 ccagccagga ccggagcgac cgctccgacc acgtcgagat ccccacccgc acgtgggacc
     3481 cgggcgcgga ccacaacagc ttcctcgacc tcaccgggcc ggtccgggtg ccctccgcct
     3541 cgttcgacga cagggcgggc accctcgacc cgcgcgtctg gcgtcaggtc tgccggctcc
     3601 acgagatctc cccgaactga gctccgcctc cggcggccgg ccgcccggct gagagatcgt
     3661 actcaccggt aactgagtat cggcgctcat gcccgggcgg cgcgggacac gcagcatggg
     3721 cggcatgacg aaacccgtga agagcacgac gaccacggcc ttctacctgc aggccgtcat
     3781 ctcgttcgtg atctccctcg ccggcctggc cgccgggatc ctctacctgc ccgtcacgac
     3841 ctgggtgcgg tcgttcctcg ccctcgggct gatgtacgtg gtgacctcga ccttcacgct
     3901 ggccaagtgc gtgcgggacc gccaggagga ggcgacggtc gtcagccgcg tggaccaggc
     3961 caggctcgac aaactgctcg ccgagcacga ccccttccgc gccgactgag cggcctccgc
     4021 gcgtgcagcc gccacgcgct cccgcacggc ttccggatca gcctggacca gccacgtaga
     4081 cgacagaatg cgacagtgcg acgacagaac ggagccatct cacaccactt caagcgagaa
     4141 tgtgacgaag tgtcatcact ttatccccaa cttattgact ttcctcgccc actatcgcct
     4201 aattcgatcg aaagtgtcac ccggtgccgt cgaaagcatc gggcgcccgt ctcgtcccgc
     4261 ctggttccag ggccggacca tgcccgtggt ccggccccgg cgtcacgccg cgaggcccgg
     4321 ccccgccgcc ggcccgtggc cacgcgcctc gcggacgggg ccgcataacg gattggggaa
     4381 ccatgaccga ggtaggcaga ggaatgacgc ggagcgtgtt ctcccggcgc gccttcacca
     4441 cggcggcgac ggccgccgcg atagcaccgc tggtcgtgtc ggctcaggcc gacgcggcgc
     4501 ccgtcggcag gaccgcgcca ccgcccgccg accccggcaa gccgcgccgc atcaccctct
     4561 acgtggagaa cctgccgaac ggcgagatgg gctacggact cgcgccgggc aaggccacga
     4621 tccccggacc gctcatcgag atggtcgagg gcgagaccct cgaagtcgag ctggtgaaca
     4681 acgcggacgt caccgccagc ctccacgtgc acggcgtgga ctacgagacc agcagcgacg
     4741 gcacgcggat gaacgacagc gtggtcgcgc cgggcgcccg gcgcgtctac gtctggcgca
     4801 cccacgcgcc gggccgccgc cccggcggga ccatcgagcc cggcagcgcg ggctactggc
     4861 actaccacga ccacgtggtc ggcaccgacc acggcacggg aggaatcaag aagggcctct
     4921 acggcccgct ggtggtccgc cgcaagggcg acacgctgcc ggacaagacc ttcaccgtcg
     4981 tcttcaacga cgtgaagatc aacaacctcg cggccgggcc gcacttcctc gcgaagatcg
     5041 gcgagcgggt cgagttcatc gtgatcaccc acgggagcgt cttccacacg ttccacatcc
     5101 acggccaccg gtgggccgac aaccgcaccg gcctgctgga gagcccccag gacccgagcc
     5161 ggatcatcga cacgaagacc accggcccgg ccgagtcgtt cggcttccag gtgatcgcgg
     5221 gagagcgtgt cggtccgggc atgtggatgt accactgcca cgtccagagc cactcggaca
     5281 tgggcatggc cggggtcttc atggtgtccg accagaacgg gaacgtgccg ggcggccacg
     5341 acatgggtgg cggttccggc ggcggcatgg acatgtccca ctgaggcaca ccggttcccg
     5401 cccgaccacg cacccggcct gacgcgagca ggtccgtcgc gaccgtcagg cggtacgcga
     5461 cgcgacggcg cccccggccc tctcgccgga gggacggggg tgcctcgccg atggagcacg
     5521 ccgccgcgga cgtgaggcgg atcagtacgg tatggccgtg actggtgacc accttcgcgc
     5581 cgggcaggcg gcgaccgcct ccaccggcgc ccagccggcc ctggactact acgtgatcac
     5641 gcccgaggcg ggggccggcg ccgtacgggc ggagggtctc gtcgtcgagg agttcgtctt
     5701 caccggcgac catcggacca tcggcctgaa caccgccacg tggagcacgg acgaccgcgc
     5761 ctggcagagc tcggcggtct tcgggcgggc catgcgcgag gatccgcgac tgcgcgcccg
     5821 cgtggtcgcc gtcggccgta cggacgccga gaccacgtat cgccgcctcg ggggaggcgc
     5881 acttcgcggc gaggcggcgc tgcgggagtg cttccgcgac accctggccc tcccggactc
     5941 cgctcccctg cggctcggcc cggaagaggg ctccgacggg ttcccggatc cccggatcta
     6001 ccgcgtcctg ttcgcgggcg accttcggcc ccccggtctc gcccgcctcg ccccggaggt
     6061 cgtcacgctc gccgaggacg ccggcgactc gcgtacccgg atcgccggca ggggcgggct
     6121 gcggacggcg cgggacgtct tcacctggga actgcgccgc atcgggcccg gcgtcgcctg
     6181 ctgcgtcgat ctcacggcgc gcctgggcac cacatccgac gacgccctcc ggccactgct
     6241 ccggagactg acgacggcga tacgtcacac gggcccgatc cccgtgacca tcgaacgctt
     6301 ctcatgattc tcacaagcgg aaatatcacc caatctcgcc attagtgccc atttccggag
     6361 caatgacaga agggccgctg aaaaccttct ccgcggaaac cgtggatacc cccgaagaag
     6421 atgtgatata gatcctttca cattggttct ggatggatct gggctctgga gcggcagcgt
     6481 gggcaaaggg cgtaagggcg agaaaaccaa cagaaccagg atttcgatca cgtacaccgc
     6541 gcttatcatc accggccttc tcctcgccgt cgtgggggcc gtggtggcga tactgggcct
     6601 gggcggggtc gtcgagttca agggcgaggt cgccggagcc aaggcggaga ccacgagcgt
     6661 cggactcgcg gtgctggtgg tgggcgcact gctggcggga atcgtggccg tcaaactgcc
     6721 ggcacaggtg accgttctgg gagacggcgg ccggagcggc ttcaccgagt ggttctccga
     6781 gttcggcgtc aggctctgcg cggttctggt ggcggccggc gtggtccttc tgatcatttc
     6841 cctcttcgcc taggccggca catgtcgtgg gtcacggctc atatggatga gcgcattgtc
     6901 gagatcgccg gagacgaggg cagctcaccc ggcagatata tgcggtacgt tttcgacgac
     6961 gacaccggca cgtacctccg tccggcggac acggagcaga tgctcgcctt ccgcgagcgg
     7021 ggcgtgaaga cggcgtacat gcaggcgcag gcgggagccg gattcgacgc ggacgcgttc
     7081 gaggccgcct ggccgggaat ctggcgtgaa ctgacgagga agcgccagga acccacgccc
     7141 gagtatttcg ccatcgtcga cacgggcctg ctctcccgtc acccccttct gcgcgggctg
     7201 atcgtggacg ggacgaacct gaccacggag cccgacggcg aggacacgaa cggccacgga
     7261 acgatggtgg cgctcatcct ggcggacggc ctgacccgcc ggccgcgtct gctcaacgtg
     7321 aaggtcgccg acggaaacgg ccacgcgacc ccccgcgacc tcgtcaaggg cattgaatgg
     7381 gtccgcgact tcgcgcggaa gacctcgtcg ccggtgtgcg tcaacatcag cctcggctgt
     7441 tactcacgcc gctggggatt ggtcgcctgc gacggcacct gcgatctctg cgaggccgcc
     7501 gtgacggcgg ccggagacgt acggatgatg acggtcgccg ccggcaacga gccgaacaag
     7561 acgacatgcc ccgccatggc cggcttacga gggcgggccg gcaacatctt cgccgtggcc
     7621 cagctcggat gggaccgcag cggagtcgga acggtcgcca tgcccgtcgg catgcaatgg
     7681 gtcccctgcg aggagaccga cgaataggcc cagcacccca cccctcgcac cgtctctcga
     7741 aatgcgcagt tcccggcagc ggtgcgcgac ccgacgaaag ggtgtgccgt ccgggtgccg
     7801 gcgtattcct ggtgtgaggg tcacggagat ggtcagacag aggcgggatc ggcggagggc
     7861 ttaccgaggg tcgtcgggta cgggagaggt gatgaccccg ccgagcagag cgtcactctc
     7921 aaccatgtcc cggtggaaca ggaccccgga gagccggctg gccagcgcga gcgcgggagc
     7981 cactgtctcg cgccggtacc gggactcctc ctgtgggccc gaaggcgtga gtccgagctc
     8041 gcgcaggtcg gcgttcaggg cgtcaggccg cgctccccag cgttcccggg gccagtccgg
     8101 ccggaaagcc gtgcgcagtt cgccctcgac cgcatgcgcg aagtggtggg atgcggcgta
     8161 gtcatgccgc atgacggaaa ccgcctcacc tccccgggac agctcccgca acgtctctgg
     8221 ccggttgcct tcccaaccgc aggcctcgaa ggcgagcgtc catccgttca cgtgggtcac
     8281 gacgaccagg tcggactctc cgtcggtctc ctcgacacgc tcccagatcc cctcccagtc
     8341 gtacggccgc atgtccgcct gggcgattcc gaacctgcgc aacgtctccc gctcatcgtg
     8401 tccgcggacg aacgtgaccg tgtatatgtc ctcccaatcg ttctgccagg aatagtcgtc
     8461 agcggtgacg ggtggcatca gcttcatccc ttcggttctt ccctgacctc tcgatcaggc
     8521 tgaccgagca acgaatgata gtcatatccg agctcgtcaa gacgggtgcg gacccaccga
     8581 gcactcgggc cgtccgctcc ttgtagaagg tgtcggcgga tcctgaaaac tggttctggc
     8641 accaaatctg tgatcttccc gcgctcagct gccggtattg gcaaggggct gcgcgtggac
     8701 cgtttccctg tctgaatcgc gcgccactgc caactggccc ccaacctgtg gtcttgaccc
     8761 gcaaggagag gcgcctgcgc gaggagaccg gctgatcctc gagcgcaacg gcgacgtgct
     8821 gttccggctc aacttgcgca ggagccggca gatcgtctgt catccaagag ctgccggtat
     8881 cccgccccag tcgtgcggag gagaccttag gcggcgaccg cggccagggc tgctgcccag
     8941 atcaccggag gcacggcgac cacacgacca aggccccgga ccgtgagcga acggccgcgt
     9001 agcgcccaag tggtggatca tgtgctgcgc ctggagggag gggcgcccgg gccggggcgg
     9061 cgcgctaccg gagggctgta ttcacaaatc gcgataattg ccgcccggaa tatgtggaga
     9121 atctccggta cattggtggg aaatatcgca ggacgcccgc ggccggggct gttcgccgcc
     9181 gtctgccgcg ctcccgaaca gcggaaacat tctcacggcc tccccttccg tatcaaagcg
     9241 gttcgctggg tcgtcccgca cataagcgcc gtcgccgagg tggtggtcat ggcccgttac
     9301 gggacgaaac ccccctgacg tgcgctgtcg tccccttggt gggcgtgagc gggtggtgtg
     9361 gagggtggcc ggtctcgctc gcgcgttccg gacatcccgt cggcgtctag gcaagctccg
     9421 tcacagtcaa ccgcagcttt cgccatttct gctgaatgcc gacaagtcta cgtttcgctc
     9481 gctatgtatt gattttttcg atcggctgac taacgctgat cgggacgcct ggtcatggag
     9541 ggagtaagaa tgcctgtcac cctggatcgc tctgaggaga tcgtctccgc gtggcgcagc
     9601 ggagccgacg tcgagggctg ggacagcccg gccggtccgc tgttcatcgg cgagtacgcc
     9661 gagtcggaga tcacgctgac ggccctggac acgcggaggc cgagctcgtg cacgggcgcc
     9721 aacaccattc cctgctgctg atcgcaccta cccggtcaat gcggaccaga acgcacagtc
     9781 acgaagggag tagcaatgcc tctcacactg gatcgctctg aggagatcgt ctccgcgtgg
     9841 cgcagcggag ccgacgtcga gggctgggac agcccggccg gtccgctgtt catcggcgag
     9901 tacgccgagt cggagatcac gctgacggcc ctggacaccc ggctggcgag ctcgtgcacc
     9961 tgcagccgct tctgctgctg atcaaggaag gatgatccga atggccgggg acttcgaccc
    10021 gtcgctggac tttttgaccg caccggcgct ggccgggctg tccgccacgc tgggatcgat
    10081 ccccggcctc acggaggcgg aggcccggct gatatgccgg agaaccgccg aagcgctgga
    10141 ggagaccgtc cgcctcaagg tcaacagggt cctgctgctg gaactcaacg ccgccaggat
    10201 cagcggaagg ctgaccgccg agacaccgca gctgcggtgg caggagtgga aggcgacggc
    10261 cgcgacgccc gagttctggc tgtccctgac cgggcactac cccacgatgc tgtccaggct
    10321 cggcacgctc atcgacaaca ggtgcgccgc ggccgtggaa ctggcccgca ggttcgccgc
    10381 cgatcgcgcg gcgctcacca cactgcccgg cggtctccga ggcgagctgg tcggcgtcga
    10441 cttcggggcg ggagacagcc atcgcggagg gcacagcgtc gccgtcctgc acggctcgca
    10501 gggcaaggtg gtctacaagc cccggtccct cgccgtggac gaggcgctgg cgcggctgat
    10561 cgaccgcctg gcaccccagc tgcccgccgg cagccgcatc cgggtacccg acgtgctgat
    10621 tcgccagggg tacggctggg cggagcacat ccagcaccgc tactgcgccg acgagacgga
    10681 gctgcggtcc ttctaccgcg gtgtagggca ctggctggcg ctgatgcggc tgatcggcgg
    10741 cagcgacctg cacatggaga acctcatcgc ggccggtccc gcgcccgtcg tcgtcgactg
    10801 cgagacgctc ttcaccccgc acgtcccggc caaaccgtcc ggatacggca acgccgtcga
    10861 ccaggcgacc gacctgctca gcggatcggt gctgcgcacc ggactccttc ccggacgcgg
    10921 cgtctcgctc gcctggcgcg gcgtcgacat gtccgccgtc gggggcctgc ccggccagca
    10981 gccgtacacg caggtgccgg tcgtggtcga cgccggcacg gacgtggcga gattgggaat
    11041 ggaacgggtc gagctgggag cggtgagcaa ccacccgagc cccgatccga tcctcgtcca
    11101 ctactgggac ctggtgctgt ccggattcac cgagctggtc gagcacctcg acatgctgga
    11161 tcggcggggt gagctcgccg ggctgctcac ggacttcgcc gaccgtcaga tccgggtcgt
    11221 gctccgcgcc accgaggcgt acgccgagct ggcccgcatg ttgtggcacc cggcctcact
    11281 gcacgacgag ccgaccgcga ggggcaaggc ggcggggttg ctggcccagc atgccgagaa
    11341 cctgcccggc gcgccgtcaa accccgaggt gatcgacgcc gaggtggccg agttgctggt
    11401 cggcgacatc cccttcttcg ccaccacccc tgctcgcggc cgtctggatg gtcctggcgg
    11461 aacctcgtac ggagacgagc aggacctcat cgcggacgcg ctgcggcgct ggcgcgaccg
    11521 cgacgcggcc ctggaccgcg aggtgatccg gtccgctctg gtcagcgcct acctcaatga
    11581 agggtggatg cctgccaaca agcgtatgac cgtgcctctc atccggcacc aggacctcga
    11641 gcggcgccgg cgccggatca cggccgggat cgcccgcagc atgcttgaca cggcggtccg
    11701 gggcgacgac ggcaccgtca cctggaccgc gccggtgctc acctcagacg gctggttcgt
    11761 acagtcgctg tctcccgacg tgtacggcgg ggcgtacggg gtcgccatca ctctggccgc
    11821 ctacgtgagt gagaccgggc agggcagggc cgacgaggtg ccggggctgg acgggctgct
    11881 cgccgatctc ctccatacga tcaggctggc cgaggagcgc gacgcggagg cacgccgcac
    11941 cggcccgcgg cgccgccccg ccaccccagg cggctatgtc ggcatcggct cgcaaatctg
    12001 gagctggctg ctgctgcgca ggctgggcac cgtcggctcg gaggaggcgg tcgcccgggc
    12061 cggcgccctg gcggggcaac ttcccgaggc ggtggccgcc gacggggtgt acgacctgct
    12121 caccggcatg gcaggcgcca tcgtgccgtt gctccgcctg tcggaacaga ccggtgacca
    12181 gcagtggtcc acgcaggccg accgcatcgg ggagcgcctg ctctcactgg cccacatcga
    12241 tgaccgggga gcacgctggc ccagcaccgc cttcccacaa gggttaggcg gggtctcaca
    12301 cggcgccacc gggatcgcct gggcgctggc ccggctcgcc gacagtgcca cggccggcgc
    12361 tgcggacttc cgcgcacttg cagacagggc ctttctgtac gaggagtcac tgtacgaccc
    12421 ggcggagaag ggctggcgtg acctgcgtga aacggacgac caccgcgtga cctccagcgc
    12481 atggtgccac ggagccgccg gcatcggcct cgtcgcggcc gaccggctgg cccgcgaagg
    12541 tgacccgcgc tgggcggacg tgctgcgccg ggccgccgcg tcgtcctggt cgaggggcat
    12601 cggctggaac cacacgctct gccacggaga cctcggcacc tgggaaatcg tgcgccgcgc
    12661 gatcgatgtg ggtgtcgggc ccgaagagct gactccggag tacctcgccg cgtacatgat
    12721 cggcagcatg gacgagcacg gcccggtgag tggcctttca cgtgacgcct tcagcccagg
    12781 tctgatgccg ggagtgggcg gcatgctcta ccaactacta cgcctgcacc ccgacacctc
    12841 cctcccctcc atcctgctcc ctgacccgga gaactgaccg ccccgtctcc tctcctgccc
    12901 gccccggttc ttcttgccgc ggtgcgctct acgaaagtcg gagtggttca atcagagtga
    12961 tccttacagc tcctgacaga aagcgcctga aacgaggccg cgacagccag gctcaggggc
    13021 gtctgacgga tgcgaaggtg aaggcgtccc ggaatgcggc gctcgggtgg gcccggcgca
    13081 cggccaccag caccggctca gggtggatgc cgagatcgtt ccacaggtga aagcagataa
    13141 gcgggtcctg cggccggtca ctggcgtagc ccagcgtctt gggatagtgg gggctggtgc
    13201 cgccgaacag gatggacggc tcgccgaagc gctcgcgcag gtggctccaa gaggcgccgg
    13261 tgcgacaggt ggcggcgatg ccgtcgcgca tcgcgttgta gtcatcagga ggcaggcgat
    13321 ggtccaggtg cagccagttg cggctgtagg ccaggtccgc atagacggag gccatggcgt
    13381 cctcggtgcc gtcgccgagg accgtggcca gagcaccggt cacgccgacg ccgttcgatc
    13441 cgccgcgttc acgcaggttg tccatgtctg cggcccaagc ttgctcggta ccgcaggcga
    13501 cggcgaccgc gtccaggtag aggcggacgg cgacctctcc gccgtgcatg cccggtcgcc
    13561 gcagagcgga gttcgcctgg gcgagcagat aggcgcgtac ggtctccagg gtgggctcgc
    13621 tcacgctcac ggcactcagc ataggctcgc tactggcgtg gcaagctgag gtggcgccag
    13681 cagatcaggg cgcagccgat gctgaggaag gcgaggtgga tgtcctcgtg gcgccgaaat
    13741 accgtaccga cgtggatctc ttcacgcgtt cgtggacggc gttgcgcagg gcggtcgccg
    13801 aacttccgga tgaggccttc gcccagcggt cgggctgcgt cggctggctc gtgcgggatc
    13861 tggtgtgcca tctggtcctc gacgcacagg atgtcctgat cacactggcg acccctacgg
    13921 aaacggaacc gacccgcgac gaagtgacgt actgggaggt ctccacgacg ccgccggccg
    13981 gtgatgatcc gctcgacgcg ctggtcgtcc ggctggccgc cgcgtacgag gagccatggc
    14041 tgctcaagtt ccatcttgac gatgtcggct ccgccgcagg ccgcgccgct gaactcgccg
    14101 acccggacct ccgggtcggg acccgcggcg aggtcctcac cgtggccgcg tacctgtccg
    14161 tgtacgtcat ggagtggacg ctgcaccacc tcgacctggt cgcgtacctg gcggacgtgc
    14221 cggaaccgcc cgtggagggg cttgcccggt ctcgcgagat gctggagagg atcgcgggga
    14281 gcgcgtttcc cccgtcgttc tcagacaagg acgcgctgct ggtcggcacc ggacggcggg
    14341 ccgtgacaga cgcggagagg aatgaactgg gcgagctggc cacgaggatc ccgctcgtcc
    14401 tcggatagcc atacgaacgc gatcggcgcg gtccggcagc ggcatcgcgc atgccggtcc
    14461 tcaaggggcg gctggtggac gagtcggcct gtaggccggg ttctaattcc gcatgctcgc
    14521 tacctgcacg gattcgctct gcaccataag caacctgcaa aaacgcttcc gttcgttgtc
    14581 atcgcttgcc aacgttctcc gtagccatgt gcccccgaag tgccccggct ccttcatgcc
    14641 cacaagcctg gcttcagact ctcgacaaga tccagtcaca tgcaagcttg ctcctgtgtt
    14701 gactcctaca cgcgatcgac gaggggtagc atcgtcgcgc ctaacctgcc ccctcgtgtt
    14761 aaggacaggc gatgtcccgc ctgattgaca gcctcacgga cgtgatcacc gtcgagtatc
    14821 gacaggttat gatcatggac ctcgatggag cgaacggagt accggaaggg gccgaggacc
    14881 tctgggaact ctcagaccgc gcgaacgtga ccaactggtt catcgccacg gcgaacgtcg
    14941 gcattatcac cagtgaggcg gatgactggc acagggtcga ggtcacgctg gagctctggg
    15001 atggagaacc gccggccgat cacgccctgt gggccagaag tgagacggta gagctgtact
    15061 cgagttccgg caagctgcgt atggtcggac cctttggtaa ctcctccggc aaactcattg
    15121 acctccgcca aaaagctcgg aactggctcg tgcgtgcaaa tgtccgccct agtcccggtg
    15181 cgcgctaccc ggaggagcag cctcccgaag gacttgagac gtaccgcctg caattctggc
    15241 ccgcactgcc gtgacacgct tgcttatcag gtaacggtgg caggtgtccg aactcgtcag
    15301 atgcgtcctc tagctgcggt gactgtccac cgctgtccac cagcgtccaa ggccgttcgt
    15361 cgacgttgtc acacacttgg tcacgcagtg agccttgctg gtcggctggc gtgacctcat
    15421 gatcacaaat agcgtccgaa gggttggctt gtatcctcct tgccattgtt gacggtccga
    15481 cgcgctgaga ctgcctgcat cagggccccc accccctgca tcatggcgcc aattgcagca
    15541 aaaacggctg cggcaactcc cagcaaaacg ctcagggata cttcggaagg agaggagcga
    15601 tctgctgcat gcgcggccgg cgaggcgact ggaggtgcgg tcacggtgac cgtcacagtg
    15661 gcccgagggt cgggacttgt cgttggcggg gcgccgacat aatcgccacg gccgatcatg
    15721 aaaatggcaa ggagcacgac cagagcagcg aggatcggca ggatcgtcca acccggcgta
    15781 agcgacttga gaggtgagcc cctcctcgcg cgacgccatt tcagttcggt ctgacggtta
    15841 gcagaggtag ccctggagct gatcgagatt acagccgcaa tggctacagc gacgagcaat
    15901 cgcgaaccag gtggtgcgat cgctgcgccg gtcatggcca ctgcaaggga aaaaaatacc
    15961 cagctagcgc tccgcagact cttgccgaac tttgcgctca cacctctagt tgtagcagct
    16021 acgactctcc cgcaaatcat gcacttagaa tttgtgacgc agtcgctaga ctaatcggcg
    16081 cggcgcacct gcctgatctc tcgtctgccg tcgacccatc gcgaagcgac agcgggccgt
    16141 ggacggaggg gcaagcccat gcctcgcgtg tacctgctcc cggtgacctt cctcgcccgc
    16201 tggttgccct gcctgcacgg ctgggcttga agccgttgcg gctgcgtggg tggacgcaca
    16261 tgctcggctt cctaggtcac ttctcgacca agtccggctc ctactccacc accctgggca
    16321 agctgcgcga tgcgaggcgt tcctttcgcg cccgccaagc ccgcgaacac ggacacgacg
    16381 ccctgaccgg cacgcccgcc gatgactcca ccctcgtcgt cggctcctgg cgctacgccg
    16441 gacagggcta cacccatccc gccgacctgt acgtcgccca gttcatccga gaggaacgcg
    16501 aggaacgccg ccgctctcac tggcccgctc gcgcttccgg ggccgccgca tgacgagaag
    16561 ggaggcgact ctggctgccg acgacactcg gatgtggagc atcgaggagg tttcgaggtt
    16621 cctcggaatc ccggtcggca cgctgtacca gtggcggcat cgccgcgtcg gtccgcgggg
    16681 ccggcggatc ggcaagtatc tgcgctacct gcccgaggac gtctacgcct gggtgcggga
    16741 gcaggagtga cggttaccga ccggtggcac aagtcccacc cgaagaaggg tgaacttgtc
    16801 tgtcccgagc acaagcgcgt ccctacacgg gagcacggtc gtggcgaccg gtggctcgtt
    16861 cggtatcggg acgagaaggg tctccagctc aagcgcagct tcgatcgcaa agctgacgct
    16921 gaccgcttcg acgctgcccg caaggcggac acggcccgtg gggactggat cgaccccaag
    16981 ctcgggcaga cgaagttcgg cgactacgcg cccgaatggt tggccgcgcg gctgcacaag
    17041 ccgaccaccg aggagaccta ccggaaccac ctgcgcaagc acatctaccc ggcctttgac
    17101 cgcgcgcccc tcgcgtcgat ccggcccacc accgtacagc aagtgggtca agggcctgcg
    17161 gtccaagggg ctcgcgcctc gcacgatcga gaccgtctac acgatctttg cgagcatcat
    17221 gcgcggggcc gtccgcgacg gtctgatcag taagacacct tgccgggaca tccgcctgcc
    17281 gcacgccgac aagaccgtga tccggctcct ggcgcccgag caggtaatga ggctgagccg
    17341 tgccatgccg ccgaagtacg ggccgttggt gcttttgggt gcggctgccg gtctgcggca
    17401 aggcgaggcg ttcgggctct cggtggatcg cgtcaggttc gctgatcaga tgatcagtgt
    17461 ggatcgtcag gtggtgatcg tggatcgtcg gccgacactg gcgactccga agagtcccgc
    17521 gtctgtgcgc gaggttccta tgccggtgtt cctcgccgaa acgctggaga agcacatcgc
    17581 cgaccactcc cccgctgatc tcctcttttc gacctcgcgc gacaacctga tgcggcggga
    17641 ctacttcaac gctcgtatct ggaagccagc gatcaaggcg gccactctgc tgccggacac
    17701 gacctttcac gacctgcggc acaccttcgc gagcacggcc ctggccgagg gcgttccgat
    17761 ctccgaggtg tcccgatggc tcggtcatga gtcgatcacc acgacggttg atctctacgg
    17821 gcatctcgtg ccggaagcct ccgagcgcgc tcgtacggcg ctcgattcgg cattccgttc
    17881 cgcgctcgat gtgcccccga tgtgccccga gggggagtaa tccgggagtc ggcccagctc
    17941 agagggcggc tggtggacga gtcggcctgt aggccgggtt ctgtggtcag ccacgggggc
    18001 tgaccggcgg ccatccatct aggaccgccg ttgccggcgg cctcaagcgg tctacccgcg
    18061 cggctcgggc gggcagccct cgaacgtcgc gcgcgggacg ttccgggaga acgtcccttc
    18121 ttgaccttgc tccgggtggg gtttaccgag ccgcccacgt caccgtgggc gctggtggtc
    18181 tcttacacca ccgtttcacc cttacccccg agaaggggcg gtctgttttc tgtggcactg
    18241 tcccgcgggt cgccccgggt cggcgttacc gaccaccctg ccctgtggag cccggacctt
    18301 cctcggcagg gcgcgaggcc ctgacgcggc cgcccggccg gctcgtccac cgtgaaagta
    18361 agcctatcgg ctcccgctcc attccccggc acggccggag gtcctgtgat gattctgcga
    18421 gttctccggc ccgagcgggc gggcggcggc ggcggcgcag gccacggacg cgccgctcac
    18481 agagatctca cagactctct cccggaacgc gaagacgggt gggtcagcct gctgcacatg
    18541 attgagattc gcggactgac caagcgctac ggcgacgtca cggccgtcga cggcctgagc
    18601 ttcgacgtac ggccgggggt agtcaccggc ttcctcggcc cgaacggcgc gggcaagacg
    18661 agcacgatgc ggatggtcct cggcctcgac aggccgacga gcggaagcgc cacgatcggc
    18721 ggacggcgct acgccgacat gcccacgccg ctgcgcgagg tgggcgcgct gctcgacgcg
    18781 cacgccgtgc atccgtaccg gagcgccgtg aaccacctgc tgaccctggc ccgcagcaac
    18841 ggcatcggcc ggggcagggt cgaggaggtg ctcggactgg ttggactggc cgacgtcgcg
    18901 gggcgccgcc cggccgggtt ctccctcggc atgaagcagc gcctcggcat cgcggcggcg
    18961 ctgctcggcg atcccggcgt cgtgctgctc gacgagcccg tcaacggcct cgacccggaa
    19021 ggaatccgct ggatccgcgg gctgacgcgc gatctggcat ccgagggccg gaccatcctg
    19081 ctctccagtc acctgatgag cgagatggcg ctcaccgccg atcacctggt cgtcgtcggc
    19141 cgcgggcggc tgctcgcgga caccggcctc gacgcgttcg tacggtccgc ggcccgggag
    19201 acggtcgtcg tgcgcacgcc gggcgcgcga cgactcgcca cactgctcga agaagccggc
    19261 gcgaccgtac ggcatggcgc cggggacgag ttgctggtga cggggatgtc cagcgccgcg
    19321 gtcggcgacg tcgccggcgc gcacggcatc gtcctgcacg aactgacgcc acggcgggcc
    19381 tcccttgagg aggcgtacct cgaactcacc ggagacagcg ccgatttcgc ctcggccgcc
    19441 gcccggcccg cggcccgctc cgaaacggag gccggagccg cgaccaccac cgcgtccatg
    19501 accaccagcg gagccgcccg atgaccgcgt acgacatcct gcgttcggag tgggggaagt
    19561 tccgcagcat ccgggcgacg ctcgggtgcc tggccggggc cctggcgacg accgcggcgt
    19621 acggctatct cttcgggctg tcctccgccc gccagtatct ggccgggtcg gcggcggacc
    19681 gggcggcctt cgaccccacc gagacgggct ttcgcgctct cgtgctcgcg ggggtgctcg
    19741 tcagcgcggt cggcgtgctc gccgtgacgt cggagtacgc ctcggggacg atgcgggtca
    19801 gtgtcgccgc cgtgcccagg cggagcctgc tgctcggcgg caaggccgcc gtcgtcgcgg
    19861 tggtcgcgct tgtcgccggg ccgccgatgg cgctggtgtc gttcacgctg agccagatct
    19921 cgctggccgc gcggaacgtg ccgagtgcgg gcctcggcga tccgggcgtg ctcgcggccg
    19981 tcgcgggcgc gggcctgttc acgggactgg tcggactgta cggcgtggcg ctcgggttcc
    20041 tgctgcgcag gtcggcgggc gccgtctcgc tagggacgtt cctgctgatc ctgcccggca
    20101 tggcggccct gttcccggac gcgatcgccg aatggatcgt cgtctggtgg ccgagcgcgg
    20161 cgggcgcgcg ggtgttcgcg gtccatccgg ggccggacgg gctggccccg ctcgcgggga
    20221 tcggggtgct ggccgccacc gtgctcgcgc tgctgtgcgc ggccgccgcc gtcttccgga
    20281 cgcgggacgt ctgacagccg tgattctggg gtgaggggcc tattctgccg ctgaccgacg
    20341 aagggaggcc gggagtggac gggcggcgcc tgctcgtggt cgacgacgag cccgtggtgc
    20401 gggaactgct ggcggccaca ctgcgcttcg cgggatacac ggtgacctcc gccgcgacgg
    20461 ggtcacaggc tctcgaggcc gcgggggccg agcctcccga tctcgtcctc ctcgacgtca
    20521 tgctgcccga catggacggg ttcgaggtca tccggcggct ccgggaccgc ccccgcccgt
    20581 tgtccgggga ccgcccggga caggtgcccg tcctgttcct caccgcgcgc gacacgaccc
    20641 aggacaaaat caacgggctg cgcctgggcg gcgacgacta cgtgaccaag cccttcgacc
    20701 tggaggagtt gctcgcccgg atcgaggccg tgctcaggcg ggccggggcg gcgccggagg
    20761 accgtacgct gcgggtggcc gacctcgaac tcgatcccga cggccaccag gtgacgcggg
    20821 cgggcgttcc cgtacgcctg tcgccgaccg agttccgcct gctgcactac ctgatcgtca
    20881 acgcgggaag ggtcgtctcc aaggcgcaga tcctggagca cgtctggcgg tacgacttcg
    20941 cgggcgacac cagcatcgtg gacacgtacg tcagctacgt gcggcggaag atcgacaagg
    21001 ccgggccgaa gctgatccac accatgcacg gcgtgggcta cgtcctgcgc gggccgcggt
    21061 cgtgatccgc cggacagcac gcggcaggag cctgtcgctg cggggacggc tcctgctgat
    21121 caccctggcc ctgctcgcgg cgggcctgac ggtcagcggc gcggtcgccg tcgccacgct
    21181 cagggcccat ctcatcgaaa gggtggacct tcagctgggg ccgatggcga cgctgttgtc
    21241 acgggtcccc gccctgatgg tgaccgcccc gctcgccggg cagaaccggg tgccgctgag
    21301 cgccctgccc ggcatggacc tgatcgacca ggtgtatctg gcgtacctgc gggcggacgg
    21361 gaccgtcggg caggagggcg gcccctggct gcgggggcgc ggtccggagc tcccccggct
    21421 cgacgccgcg gcggtccgcc ggctgggcgg gcggcccttc gacgccaggg acgaccacgg
    21481 cgccgcgtgg cgggtcgtcg ccgtcccgct ggccgcgccc ggaacgacgc cacctcggcc
    21541 cgtggcatcc ggtcaggcgc ctgacgaacc ggcggcgggg cacgccgcgg gaagcgcggc
    21601 tcagggggcc acgactgaag gggacgcggc cgaagggggc acggtcgtcg tggccgcgtc
    21661 gctcggcggg gtcaggtcga ccgtcggccg cctgacgctc gtctgcgccg cgaccgccgc
    21721 cgccctcctg acgtcgctcg ccgtcatcgg ctggttcgcc gtacgccggg ggctccggcc
    21781 gttgcgcgcg atagagcgga cggcggcggc gatcgccgcg ggcgacctgt cccggcgggt
    21841 gcccgtcccg gccgccccgc acaccgaggt cgggcggctg gccgccgcgc tcaacacgat
    21901 gctcgcccag ttggaggcgg cgttcgccgg gcgggagcgg tcgcaggccc ggatgcgccg
    21961 gttcgtcgcg gacgcgagcc acgagttgcg cacgccgctc ttcgggatca agggattcgc
    22021 ggaactgcac cggatgggcg gcctgcccga cgtcgaccac accctcggcc ggatcgagag
    22081 cgaggcggtg cgcctggtcc ggctcgtgga ggacctgctc ctgctggccc gcctcgacga
    22141 gggcgaggac gccctgccga tggacctcgc gccgatggac ctgcggacgc tcgccgccga
    22201 cgcgctccac gacctccgag cgctcgaccc cggccgtacg gtcaccctga ccggccccga
    22261 cgggggcccg gccggggccg cgccggtacg cggcgacgag gcgcgactgc ggcaggtggt
    22321 ctccaacctg gtgggcaacg ccgtcgccca cacgccgccg ggcaccccgg tccggatcgg
    22381 tgtcggcacg gtccgctcca gcgcgggcgg ccccgaaggc gtcctggtga tcgccgacga
    22441 ggggccgggg ctgcctccgg aggaggcgga gcgggtcttc gaccgcttct accgcgtgga
    22501 cgggtcacgc agccgcggcg gcgcgggagg ggccggcctt gggctggcca tcgtccggtc
    22561 gatcgtcgcc gcccacggcg ggcgggtgga actgcggacc gcgcccggcg ccggggcggc
    22621 cttccgcgtc gccctgccca tccacccggc gagccctccg gcgagcaatg ggcccgcttc
    22681 gccgcctgtc gggcctcgcc ccgcctcctg atgagccgaa gacaagcgcc gcgtcggccc
    22741 tgccggtgag cgggcatcgg gccggccccg cacccggcgg gtcacccggt gagacgctcc
    22801 gggagcgccg tgaccactgc gccgggcggt gacctcagcc gagatgcgac gtgtcgttga
    22861 acgtgcgtac gactgag
//
