MIBiG Protein Description MIBiG Cluster MiBiG Product % ID % Coverage BLAST Score E-value
BAQ25486.1 two-component_system_response_regulator BGC0001288.5 PKS 72.0 96.6 313.0 1.45e-108
EDY47143.1 two-component_system_response_regulator BGC0000845.5 other:non-nrp beta-lactam 54.0 97.0 230.0 1.57e-75
QKW60381.1 response_regulator_transcription_factor BGC0002288.2 NRPS:Type I 46.0 101.3 202.0 4.08e-65
MUL41494.1 response_regulator_transcription_factor BGC0002045.3 PKS:Type II 43.0 100.8 176.0 4.42e-55
CAH60130.1 putative_two-component_response_regulator BGC0000700.5 saccharide 44.0 103.8 176.0 1.03e-54
CAF31457.2 putative_two-component_system_response_regulator BGC0000696.5 saccharide 42.0 99.2 169.0 3.42e-52
ARV75734.1 putative_two-component_system_response_regulator BGC0001603.3 saccharide 42.0 99.2 169.0 3.42e-52
WP_002554192.1 heavy_metal_response_regulator_transcription_factor BGC0002571.2 NRPS:Type I 44.0 95.8 168.0 6.44e-52
ACN38369.1 putative_two-component_system_response_regulator BGC0000714.5 saccharide 41.0 99.2 168.0 6.83e-52
CAJ34389.1 putative_response_regulator BGC0000445.5 NRPS:Type I 42.0 99.6 166.0 5.15e-51
ABI75119.1 transcriptional_regulator_OmpR_family BGC0000188.5 other:other 38.0 100.0 154.0 7.66e-46
QCT05734.1 Tri1 BGC0001983.3 other:other 41.0 96.2 152.0 8.35e-46
AAD21216.2 BacR BGC0000310.5 NRPS:Type I 36.0 103.0 152.0 2.4e-45
AGU42430.1 Cmm22 BGC0000842.5 other:non-nrp beta-lactam 40.0 97.5 150.0 9.91e-45
AEG64695.1 response_regulator BGC0000379.5 NRPS:Type I 41.0 96.6 149.0 1.87e-44
AFI57015.1 QmnRg3 BGC0000133.5 PKS 40.0 97.5 148.0 4.84e-44
AZF85922.1 DNA-binding_response_regulator BGC0001963.2 PKS:Type I 37.0 99.2 147.0 1.66e-43
AAS79471.1 putative_two-component_system_response_regulator BGC0000035.5 PKS 39.0 99.2 145.0 6.41e-43
BBA97247.1 putative_two-component_system_response_regulator BGC0002383.3 PKS 37.0 95.3 138.0 3.39e-40
WP_237282926.1 response_regulator_transcription_factor BGC0001596.3 PKS:Type II aromatic 38.0 97.5 138.0 6.47e-40
QHZ32185.1 sensory_transduction_protein_regX3 BGC0002047.2 PKS 37.0 102.5 138.0 6.65e-40
KON97026.1 PhoP_family_transcriptional_regulator BGC0002122.2 NRPS:Type I 35.0 100.0 137.0 8.89e-40
ADM69285.1 transcriptional_response_regulator BGC0001727.3 ribosomal:RiPP 36.0 101.3 137.0 1.19e-39
CAB60254.1 MrsR2_protein BGC0000527.5 ribosomal:RiPP:Lanthipeptide 34.0 100.8 137.0 1.22e-39
BAV17023.1 putative_transcriptional_regulator BGC0001384.5 PKS 38.0 97.0 137.0 2.05e-39
QDG00834.1 two-component_system_response_regulator BGC0002028.4 PKS 37.0 97.9 139.0 2.61e-39
ARO44672.1 positive_regulation_regulator BGC0001769.5 PKS 39.0 97.5 136.0 3.49e-39
MBW8699708.1 Transcriptional_regulatory_protein_YycF BGC0002140.2 PKS 39.0 97.5 136.0 3.49e-39
BAC79018.1 repressor-response_regulator BGC0000245.5 PKS 38.0 100.0 135.0 4.69e-39
AHW57766.1 PgaR1 BGC0000262.5 PKS:Type II+saccharide:hybrid/tailoring 37.0 97.9 136.0 6.17e-39
AAX57187.2 atypical_response_regulator BGC0000201.5 PKS+saccharide:hybrid/tailoring 38.0 95.8 134.0 2.04e-38
AVO00817.1 May18 BGC0001661.5 PKS 36.0 100.0 132.0 6.94e-38
POM23776.1 Transcriptional_regulatory_protein_SrrA BGC0002369.2 PKS 39.0 97.5 130.0 3.3e-37
AGO50631.1 positive_regulation_regulator BGC0000229.5 PKS:Type II+saccharide:hybrid/tailoring 37.0 97.0 130.0 3.76e-37
BAJ07866.1 putative_repressor-response_regulator BGC0000232.5 PKS 37.0 98.3 130.0 4.16e-37
OKI81334.1 transcriptional_regulator BGC0002478.3 PKS 36.0 102.5 129.0 1.52e-36
WP_078621122.1 response_regulator_transcription_factor BGC0002000.4 PKS 37.0 103.8 129.0 2.38e-36
MCC5036779.1 response_regulator_transcription_factor BGC0002638.3 NRPS:Type I 39.0 97.0 128.0 2.52e-36
CAB93669.1 RumR_protein BGC0000545.5 ribosomal:RiPP:Lanthipeptide 36.0 99.2 128.0 3.83e-36
AOT85897.1 response_regulator BGC0001788.3 ribosomal:RiPP 33.0 98.3 127.0 7.4e-36
AWR88437.1 putative_response_regulator BGC0001522.5 PKS 37.0 96.2 125.0 2.78e-35
AEE65471.1 two_component_regulater BGC0000223.5 PKS:Type II 39.0 99.2 125.0 3.7e-35
ADI71440.1 putative_transcriptional_regulator BGC0000203.3 PKS 36.0 99.6 125.0 4.82e-35
ALK27911.1 putative_two_component_transcription_regulator BGC0001233.5 NRPS:Type I 40.0 97.0 124.0 7.77e-35
CAE53348.1 response_regulator BGC0000440.5 NRPS:Type I 36.0 96.6 124.0 9.81e-35
CAG15007.1 two_component_response_regulator BGC0000441.4 NRPS:Type I 36.0 96.6 124.0 9.81e-35
CCH32754.1 Transcriptional_regulator BGC0002070.3 PKS 38.0 96.6 124.0 1.04e-34
ASY03210.1 NsoR1 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 33.0 96.2 123.0 1.67e-34
CAH10125.1 putative_repressor-response_regulator BGC0000268.5 PKS 37.0 95.8 124.0 5.41e-34
KON97034.1 DNA-binding_protein BGC0002122.2 NRPS:Type I 32.0 100.4 122.0 6.81e-34
CAG25752.1 putative_two-component_system_response_regulator BGC0000311.6 saccharide+NRPS:Type I 35.0 96.2 121.0 1.05e-33
ADB02841.1 AzicR3 BGC0000202.5 PKS 35.0 101.7 121.0 1.16e-33
TRO56970.1 response_regulator_transcription_factor BGC0002361.3 PKS+saccharide 37.0 95.8 122.0 1.34e-33
AAM80541.1 VanRst BGC0000290.5 NRPS:Type I 36.0 97.9 120.0 2.41e-33
ABO65653.1 Subtilin_biosynthesis_regulatory_protein_SpaR BGC0000515.4 ribosomal:RiPP:Lanthipeptide 32.0 98.7 120.0 4.9e-33
ABI30224.1 McdR BGC0000526.5 ribosomal:RiPP:Lanthipeptide 31.0 98.3 120.0 4.9e-33
OWA25481.1 DNA-binding_response_regulator BGC0001438.5 PKS+saccharide:hybrid/tailoring 34.0 99.6 119.0 9.69e-33
AAK06808.1 putative_regulator_SimReg1 BGC0001072.5 PKS:Type I+saccharide+other:aminocoumarin 35.0 81.8 119.0 2.15e-32
QDG00829.1 two-component_system_response_regulator BGC0002028.4 PKS 34.0 98.3 119.0 2.27e-32
WP_082320004.1 response_regulator_transcription_factor BGC0002012.4 PKS 36.0 97.9 118.0 4.47e-32
CCC21118.1 two_component_transcriptional_regulator BGC0000171.5 PKS:Type I 38.0 98.7 117.0 5.6e-32
AGS77305.1 Two_component_response_regulator BGC0001178.5 NRPS:Type I 36.0 96.6 117.0 7.14e-32
CAA60455.1 response_regulator BGC0001040.5 NRPS:Type I+PKS 37.0 96.6 116.0 7.84e-32
OKI59850.1 transcriptional_regulator BGC0002477.3 PKS 35.0 97.0 116.0 1.22e-31
ASY03216.1 NsoR2 BGC0001701.4 ribosomal:RiPP:Lanthipeptide 30.0 94.9 115.0 1.59e-31
AAL15604.1 Sim1 BGC0000270.5 PKS 36.0 81.8 116.0 1.65e-31
AZM50118.1 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 37.0 96.6 115.0 2.85e-31
ALJ99857.1 FlsR1 BGC0001904.2 PKS:Type II aromatic 39.0 95.3 113.0 1.25e-30
QNL10611.1 Response_regulator BGC0002514.3 PKS 33.0 94.9 112.0 3.09e-30
ACX68642.1 SivR BGC0000547.5 ribosomal:RiPP:Lanthipeptide 30.0 98.3 112.0 4.45e-30
AEK64499.1 EtnR BGC0000506.4 ribosomal:RiPP:Lanthipeptide 32.0 97.9 112.0 4.68e-30
AAB91594.1 SpaR BGC0000559.4 ribosomal:RiPP:Lanthipeptide 32.0 97.9 110.0 1.3e-29
AAL15573.1 putative_response_regulator BGC0000511.5 ribosomal:RiPP:Lanthipeptide 32.0 95.3 109.0 3.6e-29
ABA00873.1 NsuR BGC0000537.3 ribosomal:RiPP:Lanthipeptide 29.0 98.3 109.0 6.72e-29
AKA59107.1 two-component_system_regulator BGC0001619.5 PKS 34.0 100.0 108.0 9e-29
ADJ56358.1 NisR BGC0000535.4 ribosomal:RiPP:Lanthipeptide 30.0 102.1 107.0 2.38e-28
BAG71485.1 response_regulator BGC0000536.3 ribosomal:RiPP:Lanthipeptide 30.0 99.6 107.0 2.38e-28
AOT85874.1 response_regulator BGC0001789.3 ribosomal:RiPP 29.0 98.3 106.0 1.01e-27
CAK15802.1 putative_DNA-binding_response_regulator,_OmpR_family BGC0000344.5 NRPS:Type I 35.0 90.3 102.0 2.21e-26
QCP68977.1 response_regulator BGC0002296.2 NRPS:Type I+PKS 42.0 53.0 100.0 5.01e-24
ACV42481.1 putative_adenylate/guanylate_cyclase BGC0000043.5 PKS 41.0 53.0 97.0 1.44e-22
AEX55159.1 putative_response_regulator_SlvR BGC0000549.3 ribosomal:RiPP:Lanthipeptide 25.0 97.9 92.0 2.35e-22
CAD91233.1 hypothetical_protein BGC0000289.5 NRPS:Type I+saccharide:hybrid/tailoring 39.0 54.7 88.0 1.2e-21
AHI58828.1 WelR3 BGC0000668.5 terpene:Monoterpene+other:other 34.0 59.3 91.0 3.39e-21
QXJ26481.1 response_regulator BGC0002370.2 NRPS:Type I 36.0 53.4 84.0 3.03e-20
AFB74478.1 putative_response_regulator BGC0000550.3 ribosomal:RiPP:Lanthipeptide 35.0 54.7 84.0 4.46e-20
DMB38_33825 DNA-binding_response_regulator BGC0002702.3 NRPS:Type I 40.0 54.7 82.0 3.26e-19
AGG35708.1 two-component_system_response_regulator BGC0000883.5 other:other 37.0 53.4 78.0 1.73e-17
ABK32284.1 Jer4 BGC0000080.5 PKS 36.0 58.5 80.0 6.81e-17
ABK32252.1 Amb4 BGC0000014.5 PKS 37.0 60.2 79.0 9.25e-17
WP_091320338.1 HAMP_domain-containing_protein BGC0002007.2 terpene 38.0 64.4 78.0 3.28e-16
ABK32275.1 Amb7 BGC0000014.5 PKS 35.0 55.1 72.0 4.22e-14
ABK32300.1 Jer7 BGC0000080.5 PKS 33.0 55.1 71.0 1.03e-13
QUQ72331.1 response_regulator_transcription_factor BGC0002349.3 PKS:Type I 36.0 52.5 68.0 1.65e-13
AAY32957.1 putative_regulatory_protein BGC0001093.3 NRPS:Type I+PKS 33.0 57.2 68.0 8.46e-13
CAL80818.1 two-component_hybrid_sensor/regulator BGC0000997.4 NRPS:Type I+PKS 37.0 51.3 68.0 9.74e-13
ADB02831.1 AzicR2 BGC0000202.5 PKS 30.0 78.4 65.0 1.74e-12
ADC45530.1 two-component_system_response_regulator BGC0000093.5 PKS:Type I 37.0 54.2 64.0 4.07e-12
AEG64693.1 two_component_system_response_regulator BGC0000379.5 NRPS:Type I 36.0 53.4 64.0 7.4e-12
AAY32960.1 putative_regulatory_protein BGC0001093.3 NRPS:Type I+PKS 33.0 55.9 64.0 1.23e-11
EHK80177.1 two-component_system_response_regulator BGC0001447.3 PKS 33.0 54.7 61.0 4.1e-11
QBK47604.1 CebA BGC0002316.2 ribosomal:RiPP 35.0 52.5 60.0 1.79e-10
AXI91558.1 FunR5 BGC0001944.2 PKS 32.0 78.8 59.0 1.87e-10
ACN39724.1 SibA BGC0000428.5 NRPS:Type I 36.0 43.2 59.0 5.6e-10
AAZ23059.1 probable_putative_response_regulator BGC0000291.5 NRPS:Type I 33.0 53.8 58.0 6.07e-10
ABB05090.1 LipReg1 BGC0001003.5 NRPS:Type I+PKS:Type I+saccharide:hybrid/tailoring 33.0 66.9 57.0 1.1e-09
AKA59096.1 LuxR-family_response_regulator BGC0001619.5 PKS 31.0 61.4 57.0 1.38e-09
CAN02021.1 putative_two-component_system,_response_regulator BGC0000528.5 ribosomal:RiPP:Lanthipeptide 32.0 59.7 56.0 2.8e-09
AXA91286.1 hybrid_sensor_histidine_kinase/response_regulator BGC0002044.2 NRPS:Type I 32.0 50.4 57.0 4.22e-09
AQP25560.1 luxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 33.0 53.8 55.0 9.2e-09
AQP25576.1 LuxR_family_response_regulator BGC0001590.5 PKS:Type II aromatic 30.0 52.5 54.0 1.27e-08
ACI88885.1 AlnR6_two_component_response_regulator BGC0000195.5 PKS:Type II 35.0 52.1 54.0 2.31e-08
WP_032643380.1 PAS_domain-containing_protein BGC0002571.2 NRPS:Type I 34.0 54.2 54.0 4.46e-08
AHX24716.1 LuxR_family_transcriptional_regulator BGC0000200.5 PKS:Type II+saccharide:hybrid/tailoring 30.0 58.9 53.0 4.64e-08
AXO35193.1 DNA-binding_response_regulator_LuxR_family BGC0001848.4 other:other 29.0 53.4 52.0 1.1e-07
EWM63043.1 two-component_system_response_regulator BGC0000679.5 terpene 29.0 53.4 51.0 1.49e-07
AQW35080.1 two-component_response_regulator BGC0001675.5 PKS 29.0 53.4 51.0 1.57e-07
QWF78530.1 Transcriptional_regulatory_protein_LiaR BGC0002142.2 PKS 29.0 64.0 50.0 5.14e-07
QWT72285.1 response_regulator_transcription_factor BGC0002430.3 NRPS:Type I+saccharide 32.0 59.7 49.0 6.81e-07
QBC75031.1 DNA-binding_response_regulator BGC0001968.3 NRPS:Type I 28.0 76.7 48.0 1.6e-06
AAU34214.1 two_component_response_regulator_MppU BGC0000388.5 NRPS:Type I 30.0 53.0 48.0 2.35e-06
WP_122215947.1 response_regulator_transcription_factor BGC0002015.4 ribosomal:RiPP 25.0 98.3 47.0 3.25e-06
BBA21064.1 putative_two-component_response_regulator BGC0001740.5 NRPS:Type I+PKS 42.0 27.5 45.0 6.91e-06
ABL09961.1 regulator BGC0000197.5 PKS:Type II+saccharide:hybrid/tailoring 39.0 29.2 46.0 9.14e-06