LOCUS       NZ_CP023694            27638 bp    DNA     linear   CON 13-JUL-2024
DEFINITION  Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete
            genome.
ACCESSION   NZ_CP023694
VERSION     NZ_CP023694.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces coeruleorubidus
  ORGANISM  Streptomyces coeruleorubidus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9335698)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008705135.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:16:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,499
            CDSs (total)                      :: 8,405
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 226
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 96 of 229
            Pseudo Genes (incomplete)         :: 175 of 229
            Pseudo Genes (internal stop)      :: 12 of 229
            Pseudo Genes (multiple problems)  :: 53 of 229
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:54:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8597883
            Orig. end                         :: 8625521
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023694.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..27638
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /region_number="37"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..27638
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="neighbouring"
                     /product="RiPP-like"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..10216
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10216
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5216](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5216)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(1759..1773)
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 15.56"
                     /tool="antismash"
     misc_feature    1825..1840
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.11"
                     /tool="antismash"
     gene            complement(1856..4081)
                     /db_xref="GeneID:91422064"
                     /locus_tag="CP976_RS39195"
                     /old_locus_tag="CP976_39225"
     CDS             complement(1856..4081)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422064"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040519.1"
                     /locus_tag="CP976_RS39195"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39225"
                     /product="NHLP family bacteriocin export ABC transporter
                     peptidase/permease/ATPase subunit"
                     /protein_id="WP_190147031.1"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.8e-38, bitscore:
                     130.3, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATAPDTRGRRRAAPPKRKVPKAGAKTVRTPTVLQMEAVECGAA
                     SLAMVLGHYGKHVPLEELRIACGVSRDGSRASNLLKAARSYGLTAKGMQMDLAALAEVK
                     SPAILFWEFNHYVVYDGMGRRFGRRGVYINDPGKGRRFVPMEDFDGSFTGVVLVMEPGE
                     DFTRGGRKPGVLGAMPARLRGTAGTMPAAVLASLLLVGVGAAVPALSRTYIDEFLIGNQ
                     TSLLPTLFTAMAACVLLTVVLTWLQQANLLHGRIISSTLSSARFLRHLLRLPVTFFSQR
                     SPADLVQRLQSNDAVAETLSRDLAAAGVDAVVVVLYAVLLYTYDPQLTFVGIGVALLNV
                     VAMRVVIRLRATRTAKLRADTARLTNTAYTGLQLIETMKATGGEDGYFRKWAGQHATTL
                     EEQQRLGVPSAWLGVVAPTLATLNSALILWIGGMRAVEGHISVGLLVAFQALVTRFTAP
                     LTRLNGVAGRIQDFAADVARLKDVENFKADPLYGRPESGESTRRLQGHVELENITFGYS
                     PLDKPLLTGFDLTVGPGQQVALVGGSGSGKSTVSRLISGLYAPWEGVIRIDGQRIEDIP
                     RGALAASVSFVDQDVFLFEGTVRDNVALWDPSIPDEAVEDALRDAALLDVITRRPGGIR
                     SKVEQDGRNFSGGQRQRLEIARALVRRPSILVLDEVTSALDAETELVVMDNLRRRGCAC
                     VVIAHRLSTVRDSDEIVVLQHGTIVERGRHEDLVARGGAYAALVRER"
     gene            complement(4078..4884)
                     /db_xref="GeneID:91422065"
                     /locus_tag="CP976_RS39200"
                     /old_locus_tag="CP976_39230"
     CDS             complement(4078..4884)
                     /codon_start=1
                     /db_xref="GeneID:91422065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386622.1"
                     /locus_tag="CP976_RS39200"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39230"
                     /product="HlyD family efflux transporter periplasmic
                     adaptor subunit"
                     /protein_id="WP_086851423.1"
                     /transl_table=11
                     /translation="MQFRQQALAKLQSPEELDLPVRFARPQGWLVLSVTVVAMAAASAW
                     AVTGSVTSTVSAPAILTHGQGSYLLQSPVAGQVTAVLAKQGERLPADSPVLKVRTPKGE
                     TVVRTLDAGRVSALAATVGQIIQTGANVAAVEKVARTTDALYATVYVPAENAASVPDDA
                     AVDLTVQSVPTQEYGVLRGHVKSVDRSAQSPQQIAAFLGDSQLGEQFTKKGRPVAVTVR
                     LDKSSATKSGYKWSSADGPPFKLNSMTLASGSIRLADQRPVDWLLP"
     gene            complement(5001..5216)
                     /db_xref="GeneID:91422066"
                     /locus_tag="CP976_RS39205"
                     /old_locus_tag="CP976_39235"
     CDS             complement(5001..5216)
                     /codon_start=1
                     /db_xref="GeneID:91422066"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128984.1"
                     /locus_tag="CP976_RS39205"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39235"
                     /product="type A2 lantipeptide"
                     /protein_id="WP_086851420.1"
                     /sec_met_domain="strepbact (E-value: 1.9e-35, bitscore:
                     120.2, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNSTPQVETVEIADAELDAVSGGLSVNAVNTVTDTVDGIAPVSGL
                     VNTAVGTVEGATGLNTAPVTNLVAGL"
     cand_cluster    5035..27638
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    5035..27638
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[15034:17638](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      complement(15035..17638)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="2"
     misc_feature    5762..5774
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     misc_feature    5857..5868
                     /note="TFBS match to AfsR, Pleiotropic regulatory for
                     antibiotic production, confidence: medium, score: 19.28"
                     /tool="antismash"
     gene            5962..7380
                     /db_xref="GeneID:91422067"
                     /locus_tag="CP976_RS39210"
                     /old_locus_tag="CP976_39240"
     CDS             5962..7380
                     /codon_start=1
                     /db_xref="GeneID:91422067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994899.1"
                     /locus_tag="CP976_RS39210"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39240"
                     /product="S1 family peptidase"
                     /protein_id="WP_150484607.1"
                     /transl_table=11
                     /translation="MSHKRIPKRKAAIAAGSVVALGAAAILLPNANASQDGSSDDAAAA
                     PKTLKAGDASDLASQLSGLLGEAFGGSYYDSDSQQLVVNVVPGDNNNVIVQAKAAGAKV
                     REVDNSWSELQGGAQTLKSDATIAGTSWAIDPRTNKLLVTADSTVTGAKWDRLESTVQS
                     LGSGMATLKKSAGTFKPFVSGGDAIFAGGSRCSLGFNVTAGDGSPAFLTAGHCTLGGNE
                     WSDTQGGQPIATVDQSTFPGDGDFALVKYDDPATEAPSEVNTGDQTVQITEAAEATVGQ
                     EVFRMGSTTGLADGQVLGLDATVNYPEGTVTGLIQTNVCAEPGDSGGSLFTQDGLAIGL
                     TSGGSGDCTVGGETFFQPVTTALEAVGATLGAGGAAGGAGEEAGAGEEAGAGEDAGAGA
                     GEEAGAGEEAGAGGEAGAGAGEEAGAGEEAGAGAGAGAGAGEQAGGEDAGAGAGAGQDT
                     GQEVGDDSGLTESR"
     gene            complement(7816..9963)
                     /db_xref="GeneID:91422068"
                     /locus_tag="CP976_RS39215"
                     /old_locus_tag="CP976_39245"
     CDS             complement(7816..9963)
                     /GO_function="GO:0016791 - phosphatase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422068"
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994900.1"
                     /locus_tag="CP976_RS39215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39245"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_150484608.1"
                     /transl_table=11
                     /translation="MSDGQSSAQAPAAARTPVGRPLLSLALASMMDEVHAHSGAVYLLA
                     QDQPVLEMAVMAGLPRAFAAPWERVGLSSPIPVADAARERRLVWVGGEEEMARHYPRIA
                     VVLPYPFALAAVPVATESTVYGAVFVTWPGGHPQELSDRERDGLTAACGRLAVRLERAA
                     EHSIPPHPETDLVASPLVGGMAGTLGTVEAARMVSRLPYGLVSLDLHGRIGFVNAAAAE
                     LLNVPVSRLLGTQLWASVPWLNDPVYEDRYRAALMSQHTASFVALRPPGEWLSFRLYPS
                     TTGLSVRITRSRAVAEMNRAAPPPDGTPTRLVTMSQVLDLASALTEAVGVQDVVQLVAD
                     EIAPAVGSQALVVLGSRANRLRVLGHRGYRDAAVVERFDGMPLTEPTPGTQVLRTGVPA
                     FFESQDQLERLYPARVATPDGFAAWAYLPLIAQGRPVGTCVLSYAEPHHFPTEERAVMT
                     SLAGLIAQALERALLYDAKHRLAHGLQEALLPHSLPSLPGIEAAARYVPATQGMDIGGD
                     FYDLVRTQGMAAAVIGDVQGHNVTAAGLMGQVRTAVRAYTAVGQAPEEVMRSTNRLLLD
                     LGADLFASCLYLRLDPAHGRAVMSRAGHPPPLLRRPDGRVRVLDLAGGPLLGIDASAVY
                     PTTEVALAPGSLLVLYTDGLVESPGTDFEEALAGLGRRLADAGDQPLDELADSLVRQEP
                     HRTDGEERLDDIALLLLRAVG"
     gene            10128..>10814
                     /db_xref="GeneID:91422069"
                     /locus_tag="CP976_RS39220"
                     /old_locus_tag="CP976_39250"
                     /pseudo=""
     CDS             10128..>10814
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422069"
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012422.4"
                     /locus_tag="CP976_RS39220"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39250"
                     /product="response regulator transcription factor"
                     /pseudo=""
                     /transl_table=11
                     /translation="MPPKSKRGGVYGRRTCAPTHPDGRFSAPTQGHGREQWGTRSTRRG
                     GVRRAEGVAVIRVLLVHDECLVRSVLAEWLRGESDLVVHDTSWRGAPGLLPSARPDVCA
                     ADLECADSYGIPPLGELCRPGPDRTRPRLLVLATANRPGLLKRAAEAGALGYVDKEGSP
                     QNLLRGIRRVAQGERFVNDSLGFGFLKAAEMPLTRRELSVLSLAAEGASIAEIAGSLHL
                     SHGTVRN"
     misc_feature    10737..10739
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(10737..12998)
                     /db_xref="GeneID:91422999"
                     /locus_tag="CP976_RS44545"
                     /old_locus_tag="CP976_39255"
     CDS             complement(10737..12998)
                     /codon_start=1
                     /db_xref="GeneID:91422999"
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128987.1"
                     /locus_tag="CP976_RS44545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39255"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_308430091.1"
                     /transl_table=11
                     /translation="MTDSPVRGGLPSRGLRFLLARWRVLLRLTAWSVLETGQTFLIGYG
                     PARALDDGFLRGRPDVGLAWLAVAGVGVLAGAYGTARVYAAVAALVEPFRDRLVERVVA
                     RGVRTGDAGSLSGLTQQVEIARDTFAGLVMVSRSFVFTAAGALAGLFTLAPPLLLVVGP
                     PLAAGVALFAVTLRPLARRQQAFLVADEALAGHLGTICPGLRDITATGAEAHLAAATGE
                     RVEAEFRAARSLAHWGVLRVASLALGGQLPIVLLLATAPWLLAHGVTTGALVGALAYVT
                     QSLLPALRNLIHGLGTSGSRLTVVLRRLAPAGSAETDGTGGDGTRSRTDGRPADTTNGS
                     AGQRRADTTNGSAGQRPADTTNPRAEQRPADTTNPRAEQRPPDTAQQHPDPRPAPGTRA
                     DRPRGGLPGAVRAPDGTLHTPTAPASDGTPRTPTASDGTSRTPTADGRTTPAGDSPPAP
                     SPPALSLSSVTFAYGPAGTPVVEDLDLTLPAGSHLAVVGPSGAGKSTLTALVAGLLTPD
                     RGTIAVGGHPVPGPEAAAARVLIPQEAYVFGGTLAENLAYLRPEPVPEEELLAAAGAVG
                     LAPLAGRLGGLGARVDPAALSAGERQLVALTRAYLSYAPLALLDEATCHLDAEAEERAE
                     RAFAARPGGTLVVVAHRVSSARRAGRVLVMDGRSAACGGHEELMRSSALYRDLVGSWAP
                     APSRRRSEPALSLRDADRVDAVAGPGLAGDGRHVVAHGPVGQVQAPGDLRDGGSLGREG
                     "
     gene            complement(13004..14755)
                     /db_xref="GeneID:91422070"
                     /locus_tag="CP976_RS39230"
                     /old_locus_tag="CP976_39260"
     CDS             complement(13004..14755)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422070"
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040505.1"
                     /locus_tag="CP976_RS39230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39260"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_150484610.1"
                     /transl_table=11
                     /translation="MSTRGDDDPATGHARTLLRTATRYSGARCAALCLVSTAATGAGLL
                     LPAALGRALDLLLAHAPATRWVLYCAGLVLILALLDAAQTVLTGTVDARSTAWLRRRLT
                     GHVLGIGPRAADRFGSGDLVARLVGNAAEAGTTPAARAALLAALAGPLGGVVALGLIDW
                     RLAAVFLAGAPVLTFLLRAVARDTAQSATRYQRAQGRIAAALAEAVEGFRTVRAAGTEG
                     RETARVLRPLAGLSEAGHRMWRVQGRAAAQAVAVAPLLQLGVVAVAGVLLTRDLLSVGE
                     VLAASRYAVLATGVGVLVGRLAGLARARAAARRLGEIRAEPATAFGERRLPDGPGRLEL
                     RDVTARRGGRTVLDGVDLVVPGGTTLAVVGRSGAGKSLLAALAGRLADPDAGEVLLDGV
                     PLRELPHDDLRHAIGYAFARPALLGGTVEQAIGLGLASPSPDHVRAAARTALADDFVRR
                     LPDGYDTAVADAPRSGGESQRLGLARAFAHGGRLLILDDALSSLDTVTERHITDALLGD
                     GPGTTRLLVAHRSATAACADAVAWLDEGRVRAVGRHEELWRLAEYRAVFGEGMDSAYAG
                     AGSEAEA"
     gene            complement(14834..14950)
                     /db_xref="GeneID:91422071"
                     /locus_tag="CP976_RS39235"
                     /old_locus_tag="CP976_39265"
     CDS             complement(14834..14950)
                     /codon_start=1
                     /db_xref="GeneID:91422071"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019983510.1"
                     /locus_tag="CP976_RS39235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39265"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_010040504.1"
                     /transl_table=11
                     /translation="MALLDLQTIESEERTDGGGASTVSLLSCISAASVLLCL"
     CDS_motif       complement(14888..14950)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQTIESEERTDGGGAS"
                     /locus_tag="CP976_RS39235_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(14834..14887)
                     /prepeptide="core"
                     /locus_tag="CP976_RS39235_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="17.10"
                     /molecular_weight="1603.0"
                     /monoisotopic_mass="1601.9"
                     /core_sequence="TVSLLSCISAASVLLCL"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQTIESEERTDGGGAS"
                     /leader_location="[14887:14950](-)"
                     /alternative_weights="1621.0"
                     /alternative_weights="1639.0"
                     /alternative_weights="1657.0"
     misc_feature    complement(14923..14943)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 19.61"
                     /tool="antismash"
     gene            complement(15035..17638)
                     /db_xref="GeneID:91422072"
                     /gene="lanKC"
                     /locus_tag="CP976_RS39240"
                     /old_locus_tag="CP976_39270"
     CDS             complement(15035..17638)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422072"
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020128990.1"
                     /locus_tag="CP976_RS39240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39270"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_150484611.1"
                     /sec_met_domain="micKC (E-value: 1.9e-232, bitscore: 772.8,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 1.4e-09, bitscore: 36.6,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 4.5e-07, bitscore:
                     27.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKRYEVYALADRHFYETPDRLRGGQEAAQGAAAHLYETARRPVP
                     EGWEAARIGDWLTMTPLGPDGEPLPGPAQGWKIHASAIRSNAERIAGIVWDYCVERRIP
                     FKFVPGPHLLHLRNTKYAPRDGSGKFVTVYPAGEEQLHEVLRELGALLEGFEGPYILTD
                     LRWGEGPLYVRYGAFARSFVVDDRGSLVPAVRDGEGRLVPDRRAPSFQVPEWVTLPEFL
                     RPHLEARNNTTTGDLPYRIEKALHFSNGGGVYTGTDTRDGRKVVLKEGRPHAGLASDGA
                     DAIARLEREKRALEQVAGTGVVPEVRDWFELGGHRFLVMDFLEGRPLNSFFAERHPLLA
                     QDPEPEAVAAYTAWALRIHRRVEEAVAAVHARGIVFNDLHVFNIMVAPDEETVFLLDFE
                     AAAPLGENGRQVVAHPGFFAPPDRRGADVDRYALACLRLALFLPVTTLFVVDRGKAAHL
                     AEVIAHQFPDVPREFLDEAVAEITREVSGRTVAAPSSPVDPGDWPYSRDSMVKAILASA
                     TPERDDRLFPGDVAQFSDGGGLGIAHGAAGVLYALDAIGAERYEEGERWLLARTAPAPV
                     GTPLGLYDGLAGVALVLDRLGHRQRALDLVEGILAERWQNLSSDLHGGLAGLGLVLGHL
                     ARTTGEAVLRERADEAARILVRRLAEPLPATPRRRAGLLRGATGPALLLLRQYEWTGRA
                     EWLQAAAVALRRDLESCVTREGGALEVDEGWRTLPYLGDGSAGIGMVLDDLVAHAPETA
                     GEFGPACSGVLTAATSRFYAQPGLFQGRAGMILHLGRTTEPGATADRLAGQIAALGWFA
                     MAYEGQLAFPGHQMMRLSMDLATGTAGCLLALGAALDPATDAHLPFLPPPNRRPT"
     misc_feature    17641..17654
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.02"
                     /tool="antismash"
     gene            17825..20275
                     /db_xref="GeneID:91422073"
                     /locus_tag="CP976_RS39245"
                     /old_locus_tag="CP976_39275"
     CDS             17825..20275
                     /codon_start=1
                     /db_xref="GeneID:91422073"
                     /gene_functions="other (smcogs) SMCOG1054: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006132918.1"
                     /locus_tag="CP976_RS39245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39275"
                     /product="SpoIIE family protein phosphatase"
                     /protein_id="WP_150484612.1"
                     /transl_table=11
                     /translation="MANVVSEGAQERGTRTLRAEGALKAIAVDQGSPEQVHRALEQALV
                     FAGAAFVAVYTPGQDGELLCLVESAGVPRTLYGLRDSYPRAGRSPVAEAHRAGRPVSMG
                     PAELAEHAQARRVPSRDFHLVALPVHGNDGGCLLAVSERPAGFDTDDRKCLELISEAVA
                     VTAPAALAEGGELPPGAFSLAMDTGRVRVGDELLDLFGLDPVEFDGRVETLLGMTVPED
                     LPSLMSVVEADHMSIGDRELEFRVLQPTGPPKWLRLSGRLLPGGEGHPARLVGTVADAS
                     TLRSDVTDVARVQRLATALATAVTVRDVGNAVVAALRRPLRADRIALAELESDRLVVTV
                     LDPPEPEVWPELWRTEWRGEWPDAPVRAMPTLAAALREGRAGIWPAGSPLERSLAEVGP
                     GGLAVLPLPAGNRMAGACLIGWDTPHDFGTDERALLTACAGLAGQALVRARAFDAEHEL
                     VGMLQRQLLPRRLPRLPGAVAVARYLPSTAGLELGGDWYDVIPLPDNHVALIIGDVQGH
                     SAGAATLMGQMRTALRAYAVEGHPPDVVVAHANRLLMDMESDLFATCAYVDVDLEEGSA
                     WCVRAGHLPPVLRYPDGGTEIAEAEGGPPLGVITRADFPMSPLRLPPGTVIALVTDGLV
                     ETPGTDIDEGMDRLAGRLAEAAPADLGLVADALLGNAPRSDDVALLLLRYDGMDLRPLR
                     ESWTVWRVPQAVGHARRFARRTLRSWGVTEDIDAVLLVVSELVTNALVHTDGRVRMDLT
                     LINNRLRVAIADASPRSPVRPASIGWEATGGRGILLVEAVSATWGTLPVSGGKQVWAEL
                     VLGR"
     gene            20368..20787
                     /db_xref="GeneID:91422074"
                     /locus_tag="CP976_RS39250"
                     /old_locus_tag="CP976_39280"
     CDS             20368..20787
                     /codon_start=1
                     /db_xref="GeneID:91422074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040498.1"
                     /locus_tag="CP976_RS39250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39280"
                     /product="CBS domain-containing protein"
                     /protein_id="WP_150484613.1"
                     /transl_table=11
                     /translation="MAQHVRDIMTSDPATVEPQTSVAEVARIMRDEDLGVVLVTDGDDL
                     RGVVTDRDLVVRSISQGGDPEQTTVAGACSDDLVTVSPDDGLDQAVQLMREHSVRRIPV
                     VDHGHPVGIVSLGDMAMERDPDSALGDISAARPNT"
     misc_feature    20389..20403
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 17.04"
                     /tool="antismash"
     gene            20968..21150
                     /db_xref="GeneID:91422075"
                     /locus_tag="CP976_RS39255"
                     /old_locus_tag="CP976_39285"
     CDS             20968..21150
                     /codon_start=1
                     /db_xref="GeneID:91422075"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP976_RS39255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CP976_39285"
                     /product="hypothetical protein"
                     /protein_id="WP_150484614.1"
                     /transl_table=11
                     /translation="MTSMETSDKPVVRRPETGWSKARRLRGKAAMRTCLPAVEDRATTR
                     TARSEPDWNIVRGED"
     misc_feature    21013..21028
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.91"
                     /tool="antismash"
     misc_feature    complement(21209..21223)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.33"
                     /tool="antismash"
     gene            21255..22322
                     /db_xref="GeneID:91422076"
                     /locus_tag="CP976_RS39260"
                     /old_locus_tag="CP976_39290"
     CDS             21255..22322
                     /EC_number="2.7.7.24"
                     /GO_function="GO:0008879 - glucose-1-phosphate
                     thymidylyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0000271 - polysaccharide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422076"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007381998.1"
                     /locus_tag="CP976_RS39260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39290"
                     /product="glucose-1-phosphate thymidylyltransferase"
                     /protein_id="WP_150484615.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 1.7e-07, bitscore:
                     30.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKALVLSGGAGTRLRPITHTSAKQLVPVANKAVLFYGLESIAEAG
                     ITDVGMIVGDTAAEIEEAVGDGSQFGLKVTYIPQERPLGLAHAVLIARDYLGDDDFVMY
                     LGDNFIVGGISGLVDEFRGNRPDAQILLTRVADPRAFGVAELDPSGQVIGLEEKPDRPK
                     SDLALVGVYLFTPLIHEAVRAIEPSWRGELEITHAIQHLIDSRADVRSTVITGYWKDTG
                     NVGDMLEVNRMVLEGMDRRIDGDVDTASETIGRVVVEEGARIVNSRIVGPAVIGSGTVI
                     SNSYVGPFTSIAENCRITDSELEFSIVLRDSSIQGVGRIEASLIGRHVEVTPAPSVPSA
                     HRFVLGDHSKVQITS"
     gene            22319..23299
                     /db_xref="GeneID:91422077"
                     /gene="rfbB"
                     /locus_tag="CP976_RS39265"
                     /old_locus_tag="CP976_39295"
     CDS             22319..23299
                     /EC_number="4.2.1.46"
                     /GO_function="GO:0008460 - dTDP-glucose 4,6-dehydratase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (4-179). E-value: 1.2e-21.
                     Score: 68.9. Matches aSDomain:
                     nrpspksdomains_CP976_RS39265_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GeneID:91422077"
                     /gene="rfbB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994908.1"
                     /locus_tag="CP976_RS39265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39295"
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="WP_150484616.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1e-16, bitscore:
                     59.9, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.6e-18,
                     bitscore: 65.8, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 1.7e-19, bitscore:
                     68.9, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLLVTGAAGFIGSRYVRALLDSDAPDAPRITVLDKLTYAGTLDN
                     LELAHPRLEFVQGDICDAELVDKLMADADQVVHLAAESHVDRSITGAADFVRTNVLGTQ
                     TLLDAALRHAVGPFVHVSTDEVYGSIETGSWPESHPLQPNSPYSASKASSDLLALAYHR
                     THGLDVRVTRCSNNYGPHQFPEKVIPLFVTNLLDGHKVPLYGEGRNVRDWLHVDDHCQG
                     IDLVRTKGRPGEVYNIGGGTELTNKELTGLLLEACGADWDRVEYVEDRKGHDLRYSVDW
                     SKARDELGYSPRHDFTTGLAETVAWYRDNRAWWEPLKQRVAQERA"
     aSDomain        22331..22855
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP976_RS39265_NAD_binding_4.1"
                     /evalue="1.20E-21"
                     /label="CP976_RS39265_NAD_binding_4.1"
                     /locus_tag="CP976_RS39265"
                     /protein_end="179"
                     /protein_start="4"
                     /score="68.9"
                     /tool="antismash"
                     /translation="VTGAAGFIGSRYVRALLDSDAPDAPRITVLDKLTYAGTLDNLELA
                     HPRLEFVQGDICDAELVDKLMADADQVVHLAAESHVDRSITGAADFVRTNVLGTQTLLD
                     AALRHAVGPFVHVSTDEVYGSIETGSWPESHPLQPNSPYSASKASSDLLALAYHRTHGL
                     DVRVTRCSNNYG"
     gene            23296..24174
                     /db_xref="GeneID:91422078"
                     /gene="rfbD"
                     /locus_tag="CP976_RS39270"
                     /old_locus_tag="CP976_39300"
     CDS             23296..24174
                     /EC_number="1.1.1.133"
                     /GO_function="GO:0008831 - dTDP-4-dehydrorhamnose reductase
                     activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (51-155). E-value:
                     3.6e-11. Score: 34.6. Matches aSDomain:
                     nrpspksdomains_CP976_RS39270_NAD_binding_4.1"
                     /codon_start=1
                     /db_xref="GeneID:91422078"
                     /gene="rfbD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995662.1"
                     /locus_tag="CP976_RS39270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39300"
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="WP_150484617.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 1.5e-109,
                     bitscore: 364.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.2e-05,
                     bitscore: 22.1, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRWLVTGAGGMLGHDVVEELTRRGEEVVGLDRAALDITAPAAVDT
                     AVRDHRPDVVVNCAAYTAVDDAESDEARALEINGDGPRLLARACAAHGARLIHVSTDYV
                     FSGEARTTPYPEDHPTGPRTAYGRTKLAGERAVLEELPGASAIVRTAWLYGVHGTNFVR
                     TMIGLEARRDTLDVVDDQRGQPTWSADVAERIADLGVRLGPDAHGVFHATDSGEATWYE
                     LAREVFSLIGADPDRVRPTSSAAFPRPAPRPAYSALAHRRWQEIGLPLPRDWRSALHEA
                     LPRIRKEGPPS"
     CDS_motif       23305..23367
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CP976_RS39270_0001"
                     /evalue="4.10E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="CP976_RS39270"
                     /protein_end="24"
                     /protein_start="3"
                     /score="6.6"
                     /tool="antismash"
                     /translation="LVTGAGGMLGHDVVEELTRRG"
     aSDomain        23449..23760
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP976_RS39270_NAD_binding_4.1"
                     /evalue="3.60E-11"
                     /label="CP976_RS39270_NAD_binding_4.1"
                     /locus_tag="CP976_RS39270"
                     /protein_end="155"
                     /protein_start="51"
                     /score="34.6"
                     /tool="antismash"
                     /translation="PDVVVNCAAYTAVDDAESDEARALEINGDGPRLLARACAAHGARL
                     IHVSTDYVFSGEARTTPYPEDHPTGPRTAYGRTKLAGERAVLEELPGASAIVRTAWLYG
                     "
     gene            24171..24974
                     /db_xref="GeneID:91422079"
                     /locus_tag="CP976_RS39275"
                     /old_locus_tag="CP976_39305"
     CDS             24171..24974
                     /codon_start=1
                     /db_xref="GeneID:91422079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057839.1"
                     /locus_tag="CP976_RS39275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39305"
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_150484618.1"
                     /transl_table=11
                     /translation="MKRHEFLRELHKVSANRNYLEIGVNDGRSLTLSRVPSIAIDPAFK
                     VVSELRCDVHLVKATSDDFFARDNPLQHLKGGRHPLRNLRRGRSPIGYWRKTTLDLSFI
                     DGMHLFEFALRDFMNVEKYSDWSSVIVLDDMLPRSIDEAARDRHTNAWTGDVFKITEVL
                     ARYRPDLVTVQVDTAPTGQLVVFGADPNNRVLHDKYDEIMAEYKIPDPQKVPEAILERA
                     GAVRPEALVEAGFWRPLVQARNRGLPRPIGWEPLRKALQQVGVSR"
     gene            complement(25080..25688)
                     /db_xref="GeneID:91422080"
                     /gene="rfbC"
                     /locus_tag="CP976_RS39280"
                     /old_locus_tag="CP976_39310"
     CDS             complement(25080..25688)
                     /EC_number="5.1.3.13"
                     /GO_function="GO:0008830 - dTDP-4-dehydrorhamnose
                     3,5-epimerase activity [Evidence IEA]"
                     /GO_process="GO:0009243 - O antigen biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0019305 - dTDP-rhamnose biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422080"
                     /gene="rfbC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040485.1"
                     /locus_tag="CP976_RS39280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39310"
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="WP_150484619.1"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 1.5e-66,
                     bitscore: 222.2, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRPLGIEGAWVLEPKVFPDDRGSFHEWYRSSEFREATGYDLSLAQ
                     ANCSVSRRGVLRGVHFADVPPSQAKYVTCVRGAVLDVVIDIRVGSPTYGQWEAVRLDDD
                     TRHAVFLAEGLGHAFMALTDDATVVYLCSAGYAPEREHGIHPLDPALGIEWPDGIEPLL
                     SPKDEQAPTLAEAEREGLLPSYEACLAFYEELRGRQQDG"
     gene            complement(25693..27633)
                     /db_xref="GeneID:91422081"
                     /locus_tag="CP976_RS39285"
                     /old_locus_tag="CP976_39315"
     CDS             complement(25693..27633)
                     /EC_number="2.4.-.-"
                     /codon_start=1
                     /db_xref="GeneID:91422081"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1123: polyprenol-monophosphomannose synthase ppm1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040483.1"
                     /locus_tag="CP976_RS39285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39315"
                     /product="glycosyltransferase family A protein"
                     /protein_id="WP_150484620.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-30,
                     bitscore: 105.6, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVKVSVIVPVYNPGIYIEDCIASLQRQSLPPEEYEVIFVDDGST
                     DETPARLDALAAEDPRMKVIHQENSGWSGKPRNVGIEASRGAFVMFVDNDDYLGDEALE
                     RMYDYGVANGADVVVGKMAGKGRGVPVELFRRNHPHATVENAPLIDSLTPHKMFRRAFL
                     DRIGLRFPEGRRRLEDHVFIAEAYLRAENVSVLSDYVCYYHLRREDGSNAGFERFDPVG
                     YFKNLREALDVVERYTEPGPVRDKLFRRWLRVEMVERLRARRFLKLPDDYRRELFAEIH
                     EVVVERFGPGVAAGLQPTQQVVAALTAADRYDDVVSFAQWEAGVAPKAAPGHVEWRDGS
                     LSVGFTAEYTSGGEPVTFPADAEATPLDDAPKDVSEAVEWVAAQTAARFGQATADLLLR
                     ERSSAAQYFMPVRFTRETVPVGDGGEVRLVLRATATVDPADLPKDGVWDALVRVKLGGW
                     TKECRLGPAPRESRPTPDVGVVGGRPVLPYWTDPHGNLSLELGVRGKRLGLGRVQQSGV
                     TVSGDHVRALLPVYVPGETEVRLRFVSAQQILEAPGTLSPATDGTGAVLAAALPVENFA
                     RGVWRVALCLAPDAARPLYTGLPFALRSAGGRVQVAPVPQPGLALRVARRARRAVGTVR
                     RKVSRIRIGGQ"
ORIGIN
        1 cagcaccgac gtgaggttct tgatgcggcc gaccttctgc tggagctcac gactgcgcgc
       61 gaactgggac gcccacgcgg cgtacgcgta gttctcggcg gcggccaccc gcagcttggg
      121 cagaccgcgc aacgtctgga aggcctggtt gttcagcttg ttggacagca caaccagccg
      181 ccgctgccac cgcacctgcc acagcccgag ccccaggaac acggccgcga tgacgacgag
      241 catgccgacc gcggccatcg ccatcggcac gctgaaccac agcagcagcc ccaggttcat
      301 cgccccgacc gtcaccgact gggcgaccgt cggaccgact cccgccagca gtctgcggat
      361 cgagctgatg cccatggccg cgctggccag ttcgccggtg gagcgctcgg tgaagaacct
      421 cgtcggcagc ctgagcagcc ggtcccacac ggccggctgg agcgtggcct cgacccggcc
      481 ctccagccgc aggatggtca ggttctgcaa cagcatgaag gccgccgcca ccacgctgct
      541 gagcatcacc gccaggcaca cctgcacgat caggtccgtc tgcgccttcg gcacgaactc
      601 gccgagcacc ttgccggtcg cgatgggcac cagcgcgccg atcgccaccg tcaccagtcc
      661 gctgagcagc agccccgtca ggtcgcggcg cgtgccctgc atgcagaacc gcagcagcct
      721 gagcgggctg agccgccgct cgggcagcgg gcggtagaac atcaccgcgc gcggctcgaa
      781 ctcgtcggcg ttcgccttct cgatcggtgt ctcacgcccg gtcgacggat ggacggcgac
      841 atatccgccg cgccgccaca gcagcgccac cggcgcgccg gacagggccc ggtggccgac
      901 cagcggcccg acgtcgtccc gccaccagcg gccgtccagg cgcacggacc gggtgcggac
      961 gcgggaagcc agggcgacct gctcgaccgg gtcgaggcgg tcgccgccgg tgcccttctg
     1021 ggtgggctcg gtgaggctga tcccggccgc ctgcgcggcg agcttgcacg ccgcgtacgt
     1081 ggcgtcggcg tcggccgcgg tggtccgctt cgacgaccgc ttgccgatcg acgcgagcag
     1141 cgtctggtcg gcctgggcgc gcaccgcctc accggccttg atgccctcgg ccgtgcgcga
     1201 ctcgtgggtg cgctccagct gttcgatcca gcggtccagc gtggtgagca gccggtactg
     1261 ctggtcgacc atggactgcc acagcgccgg gtccatcagc aggtcggccg cggcctccgc
     1321 gccgtacagc gagccgtact ggacgctgcc gggcggcacc tgcatccaga acacgtcgtc
     1381 gtccgtgggc gcggcggccc gctcggtcgc catcggcgcc tggaagagga tggacaggct
     1441 gcggcccacc cccagggcga gggcgtactc cagcgggctc gtcgtcggcg gcacgtactg
     1501 cgggttgccg tactcgtcgt acgaccaggt cgcggtgttg gcgggctggt acagctcgcg
     1561 caggccgatg cggtgcacca cgcagtcccg cagcgggcgg gccaccaggg tgtgctgggg
     1621 ccccgccacg ggcccgagca ccagcgagcc cgcctccagg cggcccaggt ggtgccagtg
     1681 gccctgctgg ccggcgtcca ccgcgaacag gtcgacggca cccgacgcga ccagccacag
     1741 cacctgcggg ccctccagat cgaggcggtt gaacccggcg cagtcgatgc gcgagcccat
     1801 ctgcccgaac gcgttgagga cgaggtcacc ctcgtgtccc tgaacggccg tcatctcacc
     1861 gctccctgac cagtgccgcg tacgctccgc cgcgcgccac caggtcctcg tgccgtcccc
     1921 gctccacgat cgtgccgtgc tggaggacga cgatctcgtc gctgtcgcgg accgtgctga
     1981 gccggtgcgc gatcaccaca caggcacagc cgcgcctgcg caggttgtcc atcacgacca
     2041 gctcggtctc cgcgtccagc gcgctcgtca cctcgtcgag gaccaggatg ctcggccggc
     2101 gcaccagcgc ccgcgcgatc tccaggcgct ggcgctgccc gccggagaag ttgcgcccgt
     2161 cctgctcgac cttgctgcgg atgccgcccg gacgccgtgt gatcacgtcg agcagggcgg
     2221 cgtcccgcag cgcgtcctcc accgcctcgt ccgggatcga cgggtcccac agcgccacgt
     2281 tgtcgcggac cgtgccctcg aagaggaaca cgtcctggtc gacgaaggag acggaggcgg
     2341 ccagcgcccc gcgcgggatg tcctcgatgc gctgtccgtc gatgcggatc acgccctccc
     2401 acggcgcgta caggccggag atcagcctgg acaccgtgga cttgccgctg cctgacccgc
     2461 cgaccagcgc gacctgctgc ccgggaccga ccgtcaggtc gaagccggtg agcaggggct
     2521 tgtcgagcgg gctgtagccg aaggtgatgt tctccagctc gacgtggccc tggaggcggc
     2581 gcgtcgactc gccggactcg gggcggccgt agagcggatc ggccttgaag ttctccacgt
     2641 ccttcagccg cgccacgtcg gccgcgaagt cctggatgcg gcccgcgacg ccgttgagcc
     2701 gggtcagcgg ggcggtgaac cgggtgacca gggcctggaa ggcgaccagc agaccgaccg
     2761 agatgtgacc ctcgaccgcc cgcatgccgc cgatccagag gatcagcgcg ctgttgaggg
     2821 tggccagcgt cggcgcgacc acgcccagcc aggcgctcgg cacgccgagc cgctgctgct
     2881 cctccagcgt ggtggcgtgc tggccggccc acttgcggaa gtagccgtcc tcgccgccgg
     2941 tcgccttcat cgtctcgatc agctgaagac cggtgtaggc ggtgttggtc agccgcgccg
     3001 tgtcggcgcg cagcttcgcc gtgcgcgtgg cccgcaggcg gatgacgacc cgcatggcca
     3061 cgacgttcag cagcgccacg ccgatgccga cgaacgtgag ctgcgggtcg taggtgtaca
     3121 gcagcaccgc gtacaggacg acgacgaccg cgtccacgcc cgccgccgcg aggtcgcgcg
     3181 acagcgtctc ggcgaccgcg tcgttggact ggagccgctg caccaggtcg gccgggctgc
     3241 gctgggagaa gaacgtgacc ggcagccgca gcagatggcg caggaagcga gcgctggaga
     3301 gggtcgagga gatgatccgg ccgtgcagca ggttggcctg ctggagccag gtgagaacga
     3361 cggtgagcag gacgcacgcc gccatcgccg tgaacagcgt cggcagcagc gaggtctggt
     3421 tcccgatcag gaactcgtcg atgtaggtgc ggctgagcgc gggcacggcc gcgccgaccc
     3481 ccaccagcag cagactcgcc aggacggcgg cgggcatcgt gcccgcggta ccgcgcagcc
     3541 gggcgggcat cgcgcccagg acgccgggct tgcggccgcc ccgggtgaag tcctcgccgg
     3601 gctccatgac cagcaccaca ccggtgaagc tgccgtcgaa gtcctccatg gggacaaacc
     3661 ggcggccctt gcccgggtcg ttgatgtaga ccccacggcg gccgaagcgg cggcccatgc
     3721 cgtcatagac gacgtagtgg ttgaactccc agaacaggat ggccggcgac ttcacctcgg
     3781 cgagggcggc caggtccatc tgcatgccct tggccgtcag gccgtaactg cgggcggcct
     3841 tgaggaggtt gctggcgcgc gagccgtcgc gggagacgcc gcaggcgatg cgcagctcct
     3901 ccagcgggac gtgcttgccg tagtggccga gcaccatcgc gagggaggcg gcgccgcact
     3961 ccacggcctc catctggagc acggtgggcg tgcggacggt cttcgccccg gccttgggca
     4021 ccttgcgctt gggcggggcg gcgcggcgcc ggccccgggt gtccggtgcg gtcgcggtca
     4081 cggcagcagc cagtcgacgg gacgctggtc ggccagccgg atcgaccccg aggccagtgt
     4141 catggagttc agcttgaacg gcggcccgtc cgcggaggac cacttgtaac cgctcttcgt
     4201 ggcggacgac ttgtccagcc ggaccgtcac ggccaccggc ctgcccttct tcgtgaactg
     4261 ctcgccgagc tggctgtccc cgaggaacgc ggcgatctgc tgcggggact gggccgagcg
     4321 gtccaccgac ttcacatggc cgcgcagcac gccgtactcc tgggtcggca ccgactgcac
     4381 ggtcaggtcg acggcggcgt cgtcggggac cgaggcggcg ttctcggcgg ggacgtagac
     4441 cgtcgcgtac aacgcgtccg tggtgcgggc gaccttctcg acggcggcga cgttcgcgcc
     4501 ggtctggatg atctgcccga cggtcgcggc gagcgcggag acacggcccg cgtcgagggt
     4561 gcggacgacg gtttcgccct tgggtgtacg gactttgagc acgggggagt cggcgggcaa
     4621 ccgctcaccc tgcttcgcga gcaccgcggt gacctggccc gccaccgggc tctggaggag
     4681 gtaactgccc tgcccgtgcg tgaggatggc gggtgcgctg acggtggagg tcaccgagcc
     4741 ggtcaccgcc catgccgagg cggccgccat cgcgaccacc gtcaccgaga gcacaagcca
     4801 gccctgcggg cgggcgaaac gcaccggaag gtcgagttct tctggtgact ggagcttggc
     4861 gagggcctgt tggcggaact gcaaggaact tccctcaccc gtagaagagg tacttacagc
     4921 cgtagcggac gtggttacgg cacccgaaga tcccggaacc gccggctgcg gctccgggag
     4981 tcaacggcac tggggctcga tcagagaccg gcgaccaggt tggtgaccgg ggccgtgttc
     5041 aggccggtgg cgccctcgac ggtgccgacg gccgtgttga ccaggccgga aaccggggcg
     5101 atgccgtcga ccgtgtcggt gacggtgttc acggcgttca cggacaggcc gccggagacg
     5161 gcgtcgagct cggcgtcggc gatctcgacg gtctcaacct ggggggtgga gttcatgatg
     5221 gaacttcctt ccgtatggat atctcacaag gggggagcgg ccccctctgg ggacagatga
     5281 cggccgcgac cgcgagtgcc ggactcccgt ttccgagtgt cctgagcggc ccccgcggtg
     5341 cgatggatca aagcacgctg cgggcgcggg cttccaatca accacccgtc ccaccaggca
     5401 acttgcgccc cagcggcacc gaagcgtgca ggtgtgggca cgccttcgtg gcgacttctt
     5461 cacatgcggc accgcatcgg cccatccagc cccttacatc gcggaacggc gaatccggca
     5521 ctcccgcccc aaaggcatga ccgacgcggt cggcgcgcgg gtaaccctcg actcggtgac
     5581 cgggttgagc attcgatgtg cagattcgct gaaggtggga ttccgctctg tgatgtcaac
     5641 agatcgtttc tggtcggaca cggatcgtgt tcgttcggta tgccgtcacg agggccgcgt
     5701 ctgaaacgcc gtcatccggc catggggcag ccgcgcgccg acgcgtttcg tcctccccgg
     5761 cgtgccgctg tgaccagggc ggtcgcagac cgcgcggtcg gtgcccgggt ggcgggagtt
     5821 ggctgattcc gcgatgcgaa tggatcactt gcaaacggaa ttgaacgccc cggacggccc
     5881 gtgcgtacca acagccatcc aggcgccccc caagagctgc cggacggcgg cacctactcc
     5941 gttccccagg aggagagaag tttgagtcac aagcgaattc cgaagcgcaa ggccgcgata
     6001 gcggcgggca gcgtggtggc gctcggcgcg gccgcgatcc tgctccccaa cgccaacgcg
     6061 tcgcaggacg gttcgtccga cgacgcggcg gccgcgccga agaccctgaa ggcgggcgac
     6121 gcctcggatc tcgcctcgca gctctccggg ctcctcggtg aggcgttcgg cggctcctac
     6181 tacgacagcg acagccagca gctcgtcgtc aacgtcgtac cgggcgacaa caacaacgtg
     6241 atcgtgcagg cgaaggcggc gggcgcgaag gtccgcgagg tcgacaacag ctggtcggag
     6301 ctccagggcg gggcgcagac cctgaagtcg gacgcgacca tcgcgggcac ctcgtgggcg
     6361 atcgacccgc gcaccaacaa gctcctggtg acggccgaca gcaccgtcac cggcgccaag
     6421 tgggacagac tggagtccac cgtgcagagc ctcggctccg gcatggcgac cctcaagaag
     6481 tccgcgggca ccttcaagcc gttcgtctcg ggcggtgacg ccatcttcgc gggcggctcg
     6541 cgctgctccc tcggcttcaa cgtcaccgcc ggcgacggct cgccggcctt cctgacggcc
     6601 ggtcactgca ccctcggcgg caacgagtgg tcggacacgc agggcggcca gccgatcgcc
     6661 accgtcgacc agtcgacctt ccccggcgac ggcgacttcg cactcgtgaa gtacgacgac
     6721 ccggcgaccg aggcgcccag cgaggtcaac accggcgacc agaccgtcca gatcaccgag
     6781 gccgcggagg cgaccgtcgg ccaggaggtc ttccggatgg gcagcaccac cgggctcgcc
     6841 gacggccagg tcctcggact cgacgccacg gtgaactacc ccgagggcac cgtcaccggc
     6901 ctcatccaga ccaacgtctg tgccgagccc ggcgacagcg gcggctcgct gttcacccag
     6961 gacggtctcg cgatcggcct gacctcgggc ggcagcggcg actgcacggt cggcggcgag
     7021 acgttcttcc agccggtgac caccgccctg gaggcggtcg gcgcgaccct cggcgcgggc
     7081 ggcgcggccg gcggcgcggg tgaagaggcc ggtgccggcg aggaagccgg tgcgggcgag
     7141 gacgccggcg caggtgccgg tgaggaagcg ggcgccggtg aggaggccgg agccggcggc
     7201 gaggccggtg ctggtgcggg cgaggaagcc ggtgccggtg aagaggccgg tgccggtgcc
     7261 ggtgctggtg ccggtgccgg tgagcaggcc ggaggcgagg acgcgggcgc cggagccggc
     7321 gccggtcagg acacgggcca ggaggtcggg gacgactccg gtctgaccga gtcccgctga
     7381 cccgagaacg tcggcagcct gtccgacgcc gccggtccgg ttccgccccc ttcctggcgg
     7441 gaccgggccg gcccacgggc gtttcggccg ccgactgggc tgagccgcgg ttccgggctg
     7501 atggcgccca cgggcgtttc ggccgccgac tgggctgagc cgcagttccg ggctgatggc
     7561 gcccaccggt gttcccggcc gccgaccggg ccgagccgcg gttccgggcc gttggcgtcc
     7621 atcgcgttcc cggccgccga gcggcttgag gcgcgttcgg gcgggtcctg gtcggcggcg
     7681 cccaccggcg ttagaagccg ccccggcccg agccgcgctc atgcggttcc ggccggcggt
     7741 ggaccgggcc ggccctccgg cgggagggcc ggcccttccg cgcgccggag gggtccgcag
     7801 gagaacgtcc gggccctatc cgacggccct gagcagcaac agggcgatgt cgtcgagccg
     7861 ttcctccccg tccgtgcggt ggggttcctg gcggacgagg ctgtcggcca gttcgtccag
     7921 cggctggtcc ccggcgtcgg ccaggcggcg gcccaggccc gcgagggcct cctcgaagtc
     7981 ggttccgggg gactcgacca gcccgtcggt gtagaggacg agcagggagc cgggggcgag
     8041 ggccacctcc gtcgtcgggt acaccgcgga ggcgtcgatg cccagcagcg ggccccctgc
     8101 caggtcgagg acgcgcaccc gcccgtccgg acgtctcagc agcggtggcg gatgacccgc
     8161 ccgggacatc acggcccggc cgtgcgccgg gtccaggcgc aggtacaggc aactggcgaa
     8221 caggtcggcc cccaggtcga gcagcagccg gttggtgctg cgcatgacct cctcgggagc
     8281 ctggcctacg gccgtgtacg cgcgcaccgc ggtgcggacc tgccccatca gcccggccgc
     8341 cgtgacgttg tggccctgca cgtccccgat caccgccgcc gccatcccct gggtgcgcac
     8401 caggtcgtag aagtcgccgc cgatgtccat gccctgcgtg gccggcacat agcgggcggc
     8461 cgcctcgatg ccgggcagcg acggcaggga gtgcggcagc agcgcctcct ggaggccgtg
     8521 cgcgagccgg tgcttggcgt cgtagagcag cgcccgctcc agtgcctggg cgatcagccc
     8581 ggccaggctg gtcatcaccg cccgctcctc cgtcgggaag tggtgcggct cggcgtagga
     8641 gagcacgcac gtccccaccg gccggccctg ggcgatcagc ggcagatacg cccaggccgc
     8701 gaacccgtcg ggcgtggcga cccgcgccgg gtagaggcgc tcaagctggt cctgcgactc
     8761 gaagaaggcc ggcacgcccg tgcgcagcac ctgtgtaccg ggagtgggct cggtcagcgg
     8821 catcccgtcg aaccgttcca ccacggccgc gtcccggtac ccgcggtgcc cgagcacccg
     8881 cagccggttc gcccgcgagc ccagcacgac cagggcctgg ctgcccacgg ccggggcgat
     8941 ctcgtccgcg acgagctgca ccacgtcctg cacccccacc gcctcggtga gcgcgctggc
     9001 caggtccagc acctgtgaca tggtgaccag ccgggtcggc gtcccgtcgg gcggcggagc
     9061 ggcccggttc atctccgcca cggcccggga cctggtgatc cggacgctga ggcccgtggt
     9121 gctcggatac agccggaacg acagccactc gccgggcggg cgcagcgcca cgaacgaggc
     9181 ggtgtgctgg ctcatcagcg ctgcccggta gcggtcctcg tacaccgggt cgttgagcca
     9241 cggcaccgac gcccacagct gcgtgccgag cagccggctg accgggacgt tcagcagctc
     9301 ggccgccgcc gcgttgacga agccgatccg cccatgcaga tccagcgaga ccagcccgta
     9361 gggcagccgg ctcaccatcc gggccgcctc gaccgtgccg agcgtgccgg ccataccgcc
     9421 caccaggggc gaggcgacca gatcggtctc gggatgcggc gggatgctgt gctcggcggc
     9481 ccgctccagc cggaccgcca gccggccgca ggccgcggtc aggccatcgc gctcccggtc
     9541 ggacagctcc tgcggatgcc cgcccggcca ggtcacgaac accgcgccgt acacggtgga
     9601 ctcggtggcc accggcaccg ccgccagggc gaacggatag ggcagcacca cggcgatccg
     9661 cggatagtgg cgggccatct cctcctcgcc gccgacccac accagcctgc gctcgcgcgc
     9721 cgcgtcggcg accgggatcg gcgagctcag ccccacccgc tcccagggcg ccgcgaacgc
     9781 ccggggcagc cccgccatca ccgccatctc cagcaccggc tggtcctgcg ccagcaggta
     9841 gaccgcgccg gagtgggcgt gcacctcgtc catcatcgag gccagcgcca aggacagcag
     9901 aggccggccg accggcgtcc tggcggccgc cggcgcctgc gcggacgact gtccgtcgga
     9961 cacgccgacc acctcctcgc acggccgcgc gaccgggccc acgaacaaat ctcctccctg
    10021 gcggcccgtc gcgcacgacg agcggcacgg ggacgaacct ggttaccgtc ggtcacagac
    10081 ccacgggcac cgttgggggc gcccgcgtac cccgaccgcc gcgacccatg ccgccgaagt
    10141 cgaagcgcgg tggggtgtat gggcgccgca cgtgcgcccc cacgcaccct gatggccggt
    10201 tctccgcgcc cacgcagggt cacggtcgcg aacaatgggg cacgcgctca acacgacgag
    10261 gtggcgtacg acgagccgag ggggtggcag tgatccgggt gcttctggtg cacgacgagt
    10321 gtctggtgcg atcggtgctg gcggagtggc tgcgggggga gtccgatctc gtggtgcacg
    10381 acacgtcgtg gcgaggcgct cccggactgc tgccgtccgc gcggccggac gtctgcgcgg
    10441 cggacctgga gtgcgcggac tcctacggca tcccgccact gggcgagctg tgccggccgg
    10501 gcccggaccg gacgcgcccg cgcctgctcg tgctcgccac cgcgaacagg cccggactgc
    10561 tgaaacgggc ggccgaggcg ggggcgctcg gctacgtcga caaggagggt tcgccgcaga
    10621 acctgctgcg cggaatccgc cgggtcgccc agggggaacg tttcgtcaac gactcgctgg
    10681 ggttcggttt cctcaaggcg gccgagatgc cgctgacccg cagagagctg agcgtgttat
    10741 ccctcgcggc cgagggagcc tccatcgcgg agatcgccgg gagcctgcac ctgtcccacg
    10801 ggaccgtgcg caactacatg gcggccatca cccgcaagac cggggcccgc aaccgcatcg
    10861 acgcgatccg catctcgcag ggacagggct ggctctgacc gccgccggga cggtgcgggc
    10921 gcccagctcc cgacgaggtc ccggtacagc gccgaggacc gcatcagctc ctcgtggccg
    10981 ccgcaggccg cgctccggcc gtccatgacc agcacacggc cggcgcggcg ggccgagctg
    11041 acgcggtggg cgacgaccac cagggtcccg cccggccgcg cggcgaaggc ccgctcggcg
    11101 cgctcctccg cctcggcgtc cagatggcag gtcgcctcgt cgagcagggc gagcggggca
    11161 tacgacagat aggcccgggt cagcgcgacc agttgccgtt cgccggccga cagggcggcc
    11221 ggatcgaccc gggcgccgag gccgccgagc cggccggcca gcggggcgag gccgaccgcc
    11281 ccggccgcgg ccagcagttc ctcctcgggc accggctccg ggcgcaggta cgcgaggttc
    11341 tcggccagcg tgccgccgaa gacgtacgcc tcctgcggga tgagcacccg ggcagcggcc
    11401 gcctccggcc cgggcacggg gtgtccgccc acggcgatgg tgccccggtc cggtgtgaga
    11461 agccccgcca cgagggcggt gagcgtggac ttgccggcac cgctgggacc gacgacggcc
    11521 aggtgtgagc cggccgggag cgtcaggtcg aggtcctcga cgacgggggt gccggcgggg
    11581 ccgtaggcga aggtgacgga ggagagggac agggctgggg gagagggggc gggcggcgaa
    11641 tcgccggcgg gggtggtccg gccgtcggcg gtaggggtgc gggaggtgcc gtcggatgcg
    11701 gtgggggtgc ggggtgtgcc gtcggatgcc ggtgcggtgg gcgtgtggag tgtgccgtcg
    11761 ggggcccgta cggctcccgg gagtccgccg cggggcctgt cggcgcgggt gccgggagcg
    11821 gggcggggat ccgggtgctg ctgtgccgtg tccggggggc gttgctccgc gcgtgggttc
    11881 gtcgtgtctg cggggcgttg ctccgcgcgt gggttcgtcg tgtctgcggg gcgttgtccc
    11941 gcactcccgt tcgtcgtgtc cgcgcggcgt tgccccgcac tcccgttcgt cgtgtccgcg
    12001 ggccgcccgt ccgtccgcga ccgcgttccg tcgccgcccg tgccgtcggt ctcggcggaa
    12061 cccgccgggg cgagcctgcg cagcaccacc gtcaggcggg agccgctggt gcccaggccg
    12121 tggatcaggt tgcgcagggc gggcagcagg gactgggtga cgtaggcgag ggcgccgacc
    12181 agggcgccgg tggtgacacc gtgggccagg agccacgggg cggtggcgag cagcagcacg
    12241 atcgggagct ggccgccgag cgccagggac gccacgcgca gtacgcccca gtgggccagg
    12301 gagcgtgccg cccggaactc cgcctcgacc cgttcgccgg tggcggcggc gaggtgtgcc
    12361 tcggcgccgg tcgccgtgat gtcccgcagg cccgggcaga tggtgcccag gtgtcccgcg
    12421 agggcctcgt cggcgacgag gaacgcctgc tgccgccggg cgagcggccg cagtgtcacc
    12481 gcgaacagcg ccacccccgc ggccaggggc ggcccgacga ccagcaggag cggcggggcg
    12541 agcgtgaaca gcccggccag ggcaccggcg gcggtgaaca cgaaggagcg ggagaccatg
    12601 accagcccgg cgaaggtgtc ccgcgcgatc tccacctgct gggtgagccc ggacagggaa
    12661 cccgcgtcac cggtccgcac tccgcgcgcg accacccgct ccacgagccg gtcccggaac
    12721 ggttcgacca gcgcggcgac ggccgcgtac acccgtgcgg tcccgtacgc cccggccagg
    12781 acaccgacac cggccaccgc cagccaggcc agcccgacat ccggccgccc tcgcaggaac
    12841 ccgtcgtcca gggcgcgggc gggcccgtac ccgatgagga aggtctgccc ggtctccagc
    12901 accgaccagg cggtgagccg cagcaggacc cgccaccggg ccagcaggaa ccgcaggcca
    12961 cgcgaaggca gtccgccccg cacggggctg tccgtcatgc ccgtcatgcc tccgcctcgc
    13021 tcccggcccc ggcgtacgcg gagtccatcc cctccccgaa caccgcccgg tactccgcga
    13081 gccgccacag ctcctcgtgc cgccccaccg cccgcacccg cccctcgtcc agccaggcca
    13141 ccgcgtcggc gcacgcggcc gtggcgctgc ggtgggcgac cagtagccgt gtggtgcccg
    13201 ggccgtcgcc gaggagggcg tcggtgatgt ggcgttccgt caccgtgtcc aggctggaga
    13261 gcgcgtcgtc gaggatcagc agccggccgc cgtgtgcgaa cgcccgggcc agccccagcc
    13321 gttgggactc gccgccggag cggggggcgt cggcgacggc cgtgtcgtat ccgtcgggga
    13381 ggcggcggac gaagtcgtcc gcgagggccg tgcgggccgc cgcccggacg tggtcggggg
    13441 agggcgatgc gagtccgagg ccgatcgcct gctcgaccgt gccgccgagg agggccggac
    13501 gggcgaaggc gtaaccgatt gcgtgccgca gatcgtcgtg cggcagctcg cgcaacggca
    13561 ccccgtcgag gagcacttcg cccgcgtccg ggtcggccag ccgcccggcg agcgcggcca
    13621 gcaaagactt gcccgcgccc gaccggccca ccacggcgag ggtcgtgccg cccggtacga
    13681 cgaggtccac cccgtcgagc acggtgcgtc cgccccgccg ggccgtcacg tcgcgtagct
    13741 ccagccgccc gggcccgtcg ggcagtcgcc gttcgccgaa cgcggtggcg ggctcggccc
    13801 ggatctcgcc gaggcgccgg gccgccgccc gggcccgggc caggcccgcg agccggccga
    13861 ccaggacgcc gacgcccgtc gcgagcaccg cgtaccgcga ggcggcgagc acctcgccca
    13921 ccgacaacag gtcccgtgtg agcagcacac cggccacggc gacgaccccg agctggagca
    13981 gcggtgccac ggcgaccgcc tgtgctgcgg cgcgtccctg cacccgccac atacggtgcc
    14041 cggcctcgga caggccggcc agtggccgca gcacccgggc cgtctcccgg ccctccgtac
    14101 ccgccgcccg gacggtgcgg aaaccctcga cggcctcggc cagcgcggcg gcgatccggc
    14161 cctgggcccg ctggtaacgc gtggcgctct gagcggtgtc acgggccacg gcacgcagca
    14221 ggaatgtcag aacgggcgcc ccggcgagga agacggccgc gagccgccag tcgatcaggc
    14281 cgagcgcgac cacacccccg aggggaccgg cgagggcggc gagcagcgcc gcacgggccg
    14341 ccggagtggt ccccgcctcg gcggcgttgc cgaccaggcg cgcgacgagg tcacccgagc
    14401 cgaagcggtc ggcggcccgc gggccgatgc ccaggacatg tccggtcagc cggcggcgca
    14461 gccacgcggt gctgcgggcg tcgacggtcc cggtcagcac ggtctgcgcc gcgtccagca
    14521 gggcgagaat cagcacgagg ccggcgcagt acagcaccca gcgggtcgcc ggggcatgcg
    14581 ccagcagaag gtcgagggcc cggcccagcg cggccggcag cagcagcccg gcaccggtgg
    14641 cggcggtgct caccaggcac agggccgcgc agcgggcccc gctgtaccgg gtggccgtgc
    14701 gcagcagcgt gcgggcgtgt ccggtcgccg ggtcgtcgtc accacgcgtg ctcatacggg
    14761 cctttcacag gattggacgg accccgggcg gcccctcccc gaaggggaag accgcccggg
    14821 gccatgacgc cggtcagagg cagagcagga cgctcgccgc gctgatgcag gagagcaggc
    14881 tcaccgtgct ggcgccgccg ccgtccgtcc gctcctcgga ctcgatcgtc tggaggtcga
    14941 gaagtgccat ggtgtgtcct tccgttgggt gtccgtccgt ggtcatccgt ggggacgggg
    15001 tggtgtcacg actccgcggg tcgcggagcc gcgttcaggt gggccgccgg ttcggcggcg
    15061 ggaggaacgg caggtgggcg tcggtcgccg ggtcgagggc cgcgccgagc gccagcaggc
    15121 accctgccgt tccggtggcg aggtccatgg acagccgcat catctggtgg ccggggaacg
    15181 cgagttggcc ctcgtaggcc atcgcgaacc agccgagtgc ggcgatctgc ccggccagcc
    15241 ggtccgcggt cgcgcccggc tcggtcgtgc ggccgaggtg caggatcatt ccggcgcggc
    15301 cctggaacag cccgggctgc gcgtagaagc gtgaggtggc ggcggtgagc acgccggagc
    15361 aggccgggcc gaactccccg gccgtttccg gggcgtgggc cacgaggtcg tcgaggacca
    15421 tgccgattcc cgcgctgccg tcgccgaggt agggcagggt ccgccagccc tcgtcgacct
    15481 ccagcgcacc gccctcgcgg gtcacgcagg actccaggtc ccggcgcagg gccacggccg
    15541 ccgcctgaag ccattcggcc cggccggtcc actcgtactg ccgcagcagc aggagcgccg
    15601 gaccggtcgc gccccgcagc agtccggcgc gccgccgggg cgtggccggg agcggctcgg
    15661 cgagccgtcg cacgaggatc cgggcggcct cgtcggcccg ctcgcgcagc accgcttccc
    15721 cggtggtgcg cgccagatgg cccaggacga ggcccagccc ggccagtccg ccgtgcaggt
    15781 cggaggagag gttctgccac ctctccgcga ggatgccctc gaccaggtcc agcgcccgct
    15841 gccggtgccc gagccggtcc aggaccaggg ccacgcccgc gagcccgtcg tacaggccga
    15901 gcggcgtgcc gaccggggcc ggcgcggtcc gggccagcag ccagcgctcg ccctcctcgt
    15961 accgctcggc gccgatcgcg tccagtgcgt agagcacccc ggccgcgccg tgggcgatcc
    16021 cgagcccgcc gccgtcggag aactgggcga cgtcgcccgg gaagagccgg tcgtcgcgct
    16081 ccggggtggc cgaggcgagg atggccttga ccatcgagtc gcggctgtac ggccagtcgc
    16141 cggggtccac cggggaggag ggagcggcca ccgtacggcc ggacacctcc cgcgtgatct
    16201 ccgcgacagc ctcgtcgagg aactcccgtg gcacgtcagg gaactgatgg gcgatcacct
    16261 cggccagatg cgccgccttg ccgcggtcga ccacgaacag cgtcgtcacg ggcaggaaca
    16321 gggccagccg cagacaggcc agggcgtacc ggtcgacgtc ggcgcccctg cggtccggcg
    16381 gcgcgaagaa gcccgggtgg gcgacgacct ggcggccgtt ctccccgagc ggggccgcgg
    16441 cctcgaagtc gaggaggaag accgtctcct cgtccggcgc gaccatgatg ttgaagacgt
    16501 gcaggtcgtt gaagacgatg ccgcgtgcgt gcaccgccgc cacggcctcc tccaccctgc
    16561 ggtggatgcg cagcgcccac gccgtgtacg cggcgacggc ctccggctcg gggtcctgcg
    16621 cgagcagcgg atgccgctcg gcgaagaacg agttgagcgg acggccctca aggaagtcca
    16681 tcaccaggaa acggtggccg ccgagctcga accagtcgcg cacctccggg accacacccg
    16741 tgcccgcgac ctgctccagc gcccgcttct cccgctccag ccgggcgatc gcgtcggcgc
    16801 cgtccgaggc gagccccgcg tgcggccggc cctccttcag cacgaccttg cgcccgtcgc
    16861 gcgtgtccgt gccggtgtac acaccgccgc cgttggagaa gtgcagcgcc ttctcgatgc
    16921 ggtacggcag gtcgcccgtc gtcgtgttgt tgcgcgcctc cagatgaggc ctgaggaact
    16981 ccggcagcgt cacccactcc ggcacctgga aggacggcgc ccgccggtcc ggcaccagcc
    17041 gcccctcgcc gtcccgcacc gccggcacca gcgagccccg gtcgtccacg acgaacgagc
    17101 gcgcgaaggc gccgtaccgg acgtacagcg gaccctcgcc ccaccgcagg tcggtcagga
    17161 tgtacggccc ctcgaacccc tccagcagcg cgcccagctc gcgcagcacc tcgtgcagct
    17221 gctcctcacc ggccggatag acggtgacga acttgccgct gccgtcgcgc ggcgcgtact
    17281 tggtgttgcg caggtgcagc aggtgcgggc ccggcacgaa cttgaagggg atccgccgct
    17341 cgacgcagta gtcccacacg atcccggcga tccgttccgc gttcgaccgg atcgccgagg
    17401 cgtggatctt ccagccctgc gccggacccg ggagcggctc gccgtccggg ccgagcggcg
    17461 tcatcgtcag ccagtcgccg atccgcgccg cctcccagcc ctcgggcacc ggccggcggg
    17521 ccgtctcgta gaggtgcgcg gccgccccct gcgcggcctc ctgcccgccc cgcagccggt
    17581 ccggcgtctc gtagaaatgc cggtcggcga gcgcgtacac ctcgtaccgc ttgtccatgc
    17641 gtccccctcc gtgacgggca ccgagccttc cagccacgcg acgggcccgg acagtcacgc
    17701 ctgtcacgag aacaccgtgc ggaacgcatg ggtaaagaca tgttcggtgg ctttcgagcg
    17761 cccgcaccgg cccgcctcca cggaacggtc acaggggctg cgcaggtgtc tcataagcgc
    17821 tctaatggcc aacgtggtca gtgagggcgc ccaagagcgc ggaacgcgaa cgctgcgtgc
    17881 cgaaggtgcc ctcaaagcga tcgcggtcga tcaggggtcg cccgaacagg tgcaccgcgc
    17941 tctcgagcag gcgctcgtct tcgccggtgc cgcgttcgtc gccgtgtaca cgcccggtca
    18001 ggacggcgaa ctgctctgcc tcgtcgagtc ggccggggtg cccaggacgc tgtacgggct
    18061 gcgcgacagc tacccgcgcg ccgggcggtc cccggtcgcc gaggcccacc gcgccgggcg
    18121 gccggtctcg atgggcccgg ccgaactcgc cgagcacgcc caggcgcggc gcgtgccgtc
    18181 ccgggacttc cacctggtcg ccctgccggt gcatgggaac gacggcggct gcctgctcgc
    18241 cgtgagcgag cgccccgccg ggttcgacac cgacgaccgc aagtgcctgg aactcatctc
    18301 cgaggcggtc gccgtcaccg ccccggccgc gctcgccgag ggcggtgaac tgccgccggg
    18361 cgccttcagc ctcgccatgg acaccggccg cgtacgggtc ggcgacgagc tgctggactt
    18421 gttcggcctg gaccccgtgg agttcgacgg ccgggtcgag accctgctcg gcatgaccgt
    18481 gccggaggac ctgccctcgc tgatgtccgt cgtggaggcg gatcacatgt ccatcggcga
    18541 ccgggagctg gagttccgcg tgctccagcc caccgggccg ccgaagtggc tccggctgag
    18601 cgggcgtctc ctgcccggcg gcgagggcca ccccgcacgg ctcgtgggca ccgtcgccga
    18661 cgcctccacg ctgcgctccg acgtcaccga cgtggcccgg gtccagcgcc tggccaccgc
    18721 gctggccacc gccgtcaccg tccgcgacgt cggcaacgcc gtggtcgccg ccctgcgccg
    18781 gccgctgagg gccgaccgga tcgccctcgc cgagctggag agcgaccggc tcgtcgtcac
    18841 cgtcctcgac ccgcccgaac ccgaggtctg gcccgagctg tggcgcacgg agtggcgggg
    18901 cgagtggccc gacgcgcccg tgcgtgccat gcccaccctc gccgccgcgc tgcgcgaggg
    18961 ccgggccggg atctggcccg ccggcagccc cctggaacgc tccctggccg aggtcggccc
    19021 cggcggcctc gccgtcctgc cgctgcccgc cgggaaccgc atggccggag cctgcctgat
    19081 cggctgggac accccgcacg acttcggcac cgacgagcgc gccctgctca ccgcctgcgc
    19141 cggcctcgcc ggacaggccc tggtgcgggc ccgggccttc gacgccgaac acgaactcgt
    19201 cggcatgctc cagcgccagc tcctgccgcg ccgcctgccc cggctgccgg gcgcggtggc
    19261 cgtcgcccgc tacctgccca gcacggccgg actcgaactc ggcggcgact ggtacgacgt
    19321 catcccgctg cccgacaacc acgtcgctct gatcatcggc gacgtccagg ggcacagcgc
    19381 cggcgccgcc accctcatgg gccagatgcg caccgccctg cgcgcctacg ccgtcgaagg
    19441 ccacccgccg gatgtcgtgg tcgcgcacgc caaccggctg ctcatggaca tggagagcga
    19501 cctcttcgcc acctgcgcct acgtcgacgt cgacctggag gagggctccg cctggtgcgt
    19561 gcgcgccggg cacctgccgc cggtgctgcg ctaccccgac ggcgggaccg agatcgcgga
    19621 ggccgagggc ggcccgcccc tcggggtgat cacccgggca gacttcccca tgagcccgct
    19681 ccggctgccg cccggcaccg tgatcgccct ggtcacggac ggcctcgtcg agacgcccgg
    19741 caccgacatc gacgagggca tggaccgcct cgccggccgg ctggccgaag ccgcccccgc
    19801 cgacctgggg ctcgtcgccg acgccctcct cggcaacgcc ccgcgcagcg acgacgtcgc
    19861 cctgctcctc ctgcgctacg acggcatgga cctgcgcccg ctgcgggaga gctggacggt
    19921 gtggcgcgtc ccgcaggcgg tcgggcacgc ccgccgcttc gcccggcgca ccctgcgctc
    19981 ctggggtgtc accgaggaca tcgacgccgt cctcctcgtc gtctccgaac tcgtcaccaa
    20041 cgccctcgtc cacaccgacg gccgggtccg catggacctc acgctcatca acaaccgcct
    20101 gcgcgtcgcc atcgccgacg cctccccgcg cagcccggtc cggccggcca gcatcggctg
    20161 ggaggccacg ggcggccggg gcatcctcct cgtcgaggcc gtgtcggcga cgtgggggac
    20221 tctgccggtc agcggcggca aacaggtgtg ggcggagctg gtcctcgggc ggtgaacctc
    20281 gcccacgatc atctggtgac cgggccggtt cgccgggtac ccgggcggcg caagacggag
    20341 aacccgagcc gaaggaagtg gaacgtcatg gctcagcatg tccgcgacat catgaccagc
    20401 gatccggcca cggtcgagcc gcagacctcc gtcgccgagg tggcccgcat catgcgcgac
    20461 gaggacctcg gcgtcgtcct ggtgacggac ggcgacgacc tgcgcggtgt ggtcaccgac
    20521 cgtgacctgg tggtccggtc gatcagtcag ggcggcgacc cggagcagac caccgtggcc
    20581 ggcgcgtgca gtgacgacct ggtcaccgtc agccccgacg acggcctgga ccaggcggtg
    20641 cagctgatgc gcgagcactc cgtgcgccgc atcccggtcg tcgaccacgg ccaccccgtg
    20701 ggcatcgtct ccctgggtga catggccatg gagcgcgatc cggactcggc gctgggcgac
    20761 atcagtgccg cgcgtcccaa cacctgacga cagcacccgg ccggacggtc ccgcgcacgc
    20821 actgtgcgcg gggccgtcgt gtgtgggggc aacagccttg tggcgtacgg gacttcagag
    20881 cgcggccggg acgtcacgac tcgtgtttgt tcggtttgtt cgtggggact cgaacagcag
    20941 cggaacgcag aaggaagatg atgagtcgtg acgtccatgg agaccagtga caagcccgtc
    21001 gtccgtcggc ccgagaccgg ctggtcgaag gcacgccgcc tgcgcggcaa ggcggcgatg
    21061 cggacctgcc tccccgccgt ggaggaccgg gccaccaccc ggaccgcgcg ctccgagccg
    21121 gactggaaca tcgtcagggg cgaggactga ccgctcccca gggggccgcg cggtgacgac
    21181 gctcgtaact ccgcgcatcg acaactaaaa gaagtgatgt tcacatccgc cggatcacga
    21241 ctatggtgaa ccgaatgaag gctctcgtgc tgtccggcgg cgcaggaaca agactgaggc
    21301 cgatcacaca cacgtcggcc aagcaactgg tgccagtggc caacaaggcc gtacttttct
    21361 atgggttgga gtcgatcgcc gaggccggca tcaccgacgt gggcatgatc gtcggggaca
    21421 cggccgcgga gatcgaggaa gcggtgggcg acgggtcgca gttcggcctg aaggtcacct
    21481 acatccctca ggagcggccc ctggggctgg cccacgcggt actgatcgcc cgggactacc
    21541 tcggcgacga cgacttcgtg atgtacctcg gcgacaactt catcgtcggc ggcatcagcg
    21601 gactcgtcga cgagttccgc ggcaaccggc ccgacgccca gatcctgctc acgcgcgtgg
    21661 cggacccacg cgccttcggc gtcgccgaac tcgatccctc cggccaggtc atcggcctgg
    21721 aggagaaacc cgaccggccc aagagcgatc tggcgctggt cggcgtctac ctgttcaccc
    21781 ccctgattca cgaagcggta cgcgccatcg aaccgtcctg gcgcggcgaa ctggagatca
    21841 cccacgccat ccagcacctg atcgactccc gcgccgacgt gcgctccacg gtcatcacgg
    21901 gctactggaa ggacaccggc aacgtcggcg acatgctcga ggtgaaccgc atggttctcg
    21961 agggcatgga ccgccggatc gacggcgacg tggacaccgc gtcggagacc atcggccgcg
    22021 tggtggtgga ggagggcgcg cggatcgtca actcccgcat cgtcggcccc gccgtcatcg
    22081 gttccggaac cgtcatcagc aactcctacg tgggtccctt cacctccatc gcggagaact
    22141 gccggatcac cgacagtgaa ctggagttct ccatcgtgct gcgggactcc tcgatccagg
    22201 gcgtcggccg gatcgaggcc tcgctgatcg gccggcacgt cgaggtgaca ccggccccca
    22261 gtgtccccag cgcccaccgc ttcgtcctcg gagaccacag caaggtacag atcacttcat
    22321 gaacctcctt gtcaccggcg cagccgggtt catcggctcc cgttacgtcc gcgcactgct
    22381 cgactcggac gcgcccgacg cgccgcgcat caccgtgctg gacaagctca cctacgccgg
    22441 caccctcgac aatctcgaac tcgcccatcc ccggctggag ttcgtgcagg gcgacatctg
    22501 cgacgccgaa ctggtcgaca agctcatggc cgacgcggac caggtcgtgc acctcgccgc
    22561 cgagtcgcat gtcgaccgct cgatcaccgg cgcggccgac ttcgtgcgca ccaacgtgct
    22621 gggcacccag accctgctgg acgccgccct gcgccacgcc gtgggcccct tcgtgcacgt
    22681 ctccaccgac gaggtctacg gctccatcga gaccggctcg tggccggaga gccaccccct
    22741 gcaacccaac tccccgtact cggcctccaa ggcctcctcc gacctgctcg ccctggccta
    22801 ccaccgcacc cacggcctgg acgtgcgcgt cacccgctgc tccaacaact acggcccgca
    22861 tcagttcccc gagaaggtca tcccgctgtt cgtcaccaac ctcctcgacg gacacaaggt
    22921 gccgctgtac ggcgagggcc gcaacgtccg ggactggctg cacgtggacg accactgcca
    22981 ggggatcgac ctcgtccgca ccaagggccg gcccggcgag gtctacaaca tcggcggcgg
    23041 caccgagctc accaacaagg aactcaccgg cctgctcctc gaggcctgcg gcgcggactg
    23101 ggaccgggtg gagtacgtcg aggaccgcaa gggccacgac ctgcgctact ccgtcgactg
    23161 gtccaaggcc cgcgacgaac tcggctacag cccccgccac gacttcacca ccggcctcgc
    23221 cgaaaccgtc gcctggtacc gcgacaaccg cgcctggtgg gagcccctga agcagcgcgt
    23281 cgcccaggag cgcgcatgag gtggctggtc accggggcgg gcggaatgct cggccacgac
    23341 gtggtcgagg agctcacccg gcgcggcgag gaggtggtgg ggctggaccg tgcggccctg
    23401 gacatcaccg cgcccgcggc cgtcgacacg gctgtgcgcg accaccggcc cgacgtggtc
    23461 gtgaactgcg ccgcatacac ggccgtggac gacgccgaga gcgacgaggc ccgcgccctg
    23521 gagatcaacg gggacggacc gcgcctgctc gcccgggcct gcgccgcgca cggcgcccgc
    23581 ctgatccacg tctccacgga ctacgtcttc tccggcgagg cccgcacgac cccctacccg
    23641 gaggaccacc cgacgggccc gcgcaccgcc tacggccgca ccaaactggc cggggagcgg
    23701 gccgtgctgg aggaactgcc cggagcgagc gcgatcgtgc gcacggcttg gctctacggg
    23761 gtccacggca ctaacttcgt gcggaccatg atcggactcg aagcccgccg cgacaccctc
    23821 gacgtcgtcg acgaccagcg cgggcagccc acctggagcg cggacgtcgc cgaacggatc
    23881 gccgacctcg gcgtacggct cggccccgac gcgcacggcg tcttccacgc caccgactcc
    23941 ggcgaggcca cctggtacga gctggcacgc gaggtgttct ccctcatcgg cgccgacccg
    24001 gaccgggtcc gccccaccag cagcgcggcc ttcccccggc ccgcgccccg cccggcgtac
    24061 agcgccctcg cacaccgccg gtggcaggag atcggcctgc cgctgccgcg cgactggcgc
    24121 tccgccctgc acgaagcact gccccgtatc cgcaaggaag gtcccccttc gtgaaacgcc
    24181 atgagttcct ccgggaactg cacaaggtca gcgccaatcg caactacctg gagatcggcg
    24241 tcaacgacgg ccgcagcctg acgttgtccc gcgtccccag catcgcgatc gaccccgcct
    24301 tcaaggtggt gtcggagctg aggtgcgacg tccacctggt gaaggccacc agcgacgact
    24361 tcttcgcccg tgacaacccc ctccagcacc tcaagggcgg ccgtcacccg ctgcgcaacc
    24421 tgcgccgcgg ccgcagcccg atcggttact ggcgcaaaac gacgctggac ctgtcgttca
    24481 tcgacggcat gcacctgttc gagttcgcac tgcgcgactt catgaacgtc gagaagtact
    24541 cggactggtc cagcgtgatc gtcctcgacg acatgctgcc gcgcagcatc gacgaggcgg
    24601 cccgggaccg gcacaccaac gcctggaccg gcgacgtctt caagatcacc gaggtgctgg
    24661 cgcgttaccg ccccgacctg gtcacggtgc aggtggacac cgccccgacc ggccagctcg
    24721 tcgtcttcgg cgccgacccg aacaaccggg tcctgcacga caagtacgac gagatcatgg
    24781 ccgagtacaa gatccccgac ccgcagaagg tccccgaggc gatcctggaa cgggccggtg
    24841 cggtgcgccc cgaggccctc gtggaagccg gcttctggcg ccccctcgtc caggcccgca
    24901 accgcggcct gccccgcccc atcggctggg agcccctgcg caaggccctg caacaggtgg
    24961 gcgtcagccg ctgaggcctc cggcgccttg cggatccgag cccgggcgct gcgcgcgccc
    25021 gggccttcgg cgtgccgggg tgaggtgact cggcctttcc gccgggagcg ccgcggatgt
    25081 cagccgtcct gctgccgccc ccgcagctcc tcgtaaaacg ccaggcaagc ctcatacgac
    25141 ggcagcaagc cctcgcgttc ggcttcggcc agggtcgggg cctgttcgtc cttgggggag
    25201 aggagcggtt cgattccgtc gggccactcg atgcccaggg ccgggtcgag cgggtggatg
    25261 ccgtgttcgc gttccggggc gtagcccgcc gagcacaggt acaccaccgt cgcgtcgtcc
    25321 gtcagggcca tgaacgcgtg gcccagtccc tccgcgagga acaccgcgtg ccgggtgtcg
    25381 tcgtcgagcc gtaccgcttc ccactgcccg taggtggggg agcccacgcg gatgtcgatc
    25441 accacgtcga ggacggcacc gcgcacacag gtgacgtact tggcctggct gggcggcaca
    25501 tccgcgaagt gcacaccccg cagcacgccc cgccgggaga ccgagcagtt ggcctgggcc
    25561 agggacaggt cgtagcccgt ggcctcacgg aactccgagc tgcggtacca ctcgtggaag
    25621 ctgccccggt cgtccgggaa gaccttgggc tccagcaccc aggcaccctc tatccccagt
    25681 ggtcgcatgc cgtcactgcc ctccgatcct gatgcgggaa accttccgac gcacggtacc
    25741 gaccgcgcgt cgcgcacgcc gcgccacccg cagcgccagg ccgggctgcg gcaccggcgc
    25801 cacctgcaca cgcccgcccg ccgagcgcag cgcgaacggc agcccggtgt acagcggccg
    25861 ggcggcgtcc ggggccaggc acagggccac ccgccagacg ccgcgcgcga aattctccac
    25921 gggcagggcc gccgccagca cggcccccgt cccgtccgtg gcgggggaga gcgtgccggg
    25981 cgcctcgagg atctgctggg cggagacgaa ccgcagccgc acttcggtct cgccggggac
    26041 gtacaccgga agcagcgcac ggacgtggtc gccggagacg gtgacgccgg actgctgcac
    26101 gcggcccagc ccgagccgct tgccacgcac tccgagctcc agggagaggt tgccgtgcgg
    26161 atccgtccag tacggcagca ccggccgacc cccgacgacc cccacgtccg gcgtgggccg
    26221 gctctcccgt ggcgccgggc ccagccggca ctccttggtc cagccgccca gtttgacccg
    26281 gacgagcgcg tcccagacgc cgtccttcgg caggtcggcc gggtcgacgg tggcggtcgc
    26341 ccgcagcacc agccggacct ccccgccgtc cccgacgggc acggtctcgc gggtgaaccg
    26401 cacgggcatg aagtactgcg cggcgctgga ccgctcccgc agcagcaggt ccgcggtggc
    26461 ctggccgaag cgcgcggcgg tctgcgcggc cacccactcc accgcctcgg acacatcctt
    26521 gggcgcgtcg tccagcggcg tcgcctcggc gtcggccggg aaggtcaccg gctccccgcc
    26581 ggaggtgtac tcggccgtga agccgacgct gagggagccg tccctccact ccacgtgccc
    26641 gggggccgcc ttgggcgcga caccggcctc ccactgggcg aaggagacga cgtcgtcgta
    26701 ccggtcggcc gcggtcagtg cggcgacgac ctgctgcgtc ggctggagcc cggccgcgac
    26761 gccgggaccg aaccgctcga cgacgacctc gtggatctcg gcgaacagct ccctgcggta
    26821 gtcgtccggc agcttgagga agcgccgggc tcgcagccgc tcgaccatct ccacgcgcag
    26881 ccagcgccgg aagagcttgt cacgcaccgg tccgggctcg gtgtaccgct cgacgacgtc
    26941 gagggcctca cggaggttct tgaagtagcc gaccggatcg aagcgttcga aaccggcgtt
    27001 ggagccgtcc tcccgccgga ggtggtagta gcagacgtag tcgctgagca cggagacgtt
    27061 ctccgcgcgc agatacgcct cggcgatgaa gacgtggtcc tccaggcgcc ttctgccctc
    27121 ggggaagcgc aggccgatgc ggtccaggaa ggcgcggcgg aacatcttgt gcggggtgag
    27181 gctgtcgatg agcggggcgt tctcgacggt ggcgtgcggg tggttgcggc ggaacagttc
    27241 caccggcacg ccgcggccct tgccggccat cttgccgacg acgacatcgg caccgttggc
    27301 cacgccgtag tcgtacattc gctccagggc ctcgtcgccc aggtagtcgt cgttgtcgac
    27361 gaacatgacg aacgcgccgc gggaggcctc gatgccgaca ttgcggggct tgcccgacca
    27421 gccggagttc tcctggtgga tgaccttcat ccgggggtcc tcggcggcga gcgcgtcgag
    27481 ccgggccggc gtctcgtcgg tcgagccgtc gtcgacgaag atcacctcgt actcttcggg
    27541 aggcaacgac tgcctctgga gcgaggcgat gcagtcctcg atgtagatcc ccgggttgta
    27601 gacggggacg atgacgctga ccttgaccgg catcgggt
//
