LOCUS       NZ_CP023694            21032 bp    DNA     linear   CON 13-JUL-2024
DEFINITION  Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete
            genome.
ACCESSION   NZ_CP023694
VERSION     NZ_CP023694.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces coeruleorubidus
  ORGANISM  Streptomyces coeruleorubidus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9335698)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008705135.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:16:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,499
            CDSs (total)                      :: 8,405
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 226
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 96 of 229
            Pseudo Genes (incomplete)         :: 175 of 229
            Pseudo Genes (internal stop)      :: 12 of 229
            Pseudo Genes (multiple problems)  :: 53 of 229
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:54:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 8547188
            Orig. end                         :: 8568220
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023694.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21032
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="36"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21032
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21032
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11032](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11032)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(145..582)
                     /db_xref="GeneID:91422016"
                     /locus_tag="CP976_RS38950"
                     /old_locus_tag="CP976_38980"
     CDS             complement(145..582)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422016"
                     /gene_functions="regulatory (smcogs) SMCOG1284:
                     transcriptional regulator, MarR family"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134821.1"
                     /locus_tag="CP976_RS38950"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_38980"
                     /product="MarR family transcriptional regulator"
                     /protein_id="WP_150484567.1"
                     /transl_table=11
                     /translation="MLDAQVTKAPPSLLYMVKQVELVVRSHLDELVRPSGITALQYTAL
                     TVLERHDGLSAAQLARDSFVTAQSIADLVRSLEGRGLVRRERNPRNRRERLILLTDAGR
                     ELLARHAGPVRELEERMVRDLTAHQTEQFRQALAKAWHALS"
     misc_feature    complement(616..632)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.66"
                     /tool="antismash"
     misc_feature    647..656
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 15.11"
                     /tool="antismash"
     misc_feature    complement(647..660)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.35"
                     /tool="antismash"
     misc_feature    complement(647..661)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.11"
                     /tool="antismash"
     misc_feature    complement(648..661)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 18.15"
                     /tool="antismash"
     misc_feature    complement(649..662)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.89"
                     /tool="antismash"
     gene            686..2140
                     /db_xref="GeneID:91422017"
                     /locus_tag="CP976_RS38955"
                     /old_locus_tag="CP976_38985"
     CDS             686..2140
                     /EC_number="1.2.1.-"
                     /GO_function="GO:0016620 - oxidoreductase activity, acting
                     on the aldehyde or oxo group of donors, NAD or NADP as
                     acceptor [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422017"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020127665.1"
                     /locus_tag="CP976_RS38955"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_38985"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_150484568.1"
                     /sec_met_domain="Aldedh (E-value: 3.7e-175, bitscore:
                     581.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTFEREPGRLFVGGQWREAADGARTEVVDPSRGTVVTTVAEAGP
                     ADVDAAVRAAREAYDEGAWSGLSGRERGRVLHRVAQLIRENADEIAALESLDVGKPITL
                     CGAVDVTNAANDYEYFANLAQSQDGALRDTPMNALAYTKREPLGVVAAITPFNFPLILA
                     GSKIGPALAAGNTVVHKPADETPLSALYMARLFQEAGVPDGVVNVVTGSGPVAGEALLR
                     HRGVDKIAFTGSTAIGRHVASVAGEALKPVTMELGGNAAHLVFEDADLEKAVGAVIKGF
                     VFNTGQFCMGGPRLLVARSVYPTLLGILAEAVPGVPVGDPRDPATVIGPMAAEKHLKKV
                     EEYVALARKEGARIVCGGERLDLDGGYYYRPTVIADLSNDSRVIQEEIFGPVLTVQPFD
                     DEDEAVALANSTPYGLASGVQTTNLARAHRVADRLQAGIVWVNDWAMLDPAVPFGGVKD
                     SGYGREYGPEALAGYTKVKSVVVSLD"
     gene            2165..3271
                     /db_xref="GeneID:91422018"
                     /locus_tag="CP976_RS38960"
                     /old_locus_tag="CP976_38990"
     CDS             2165..3271
                     /NRPS_PKS="Domain: PKS_ER (24-362). E-value: 1.2e-15.
                     Score: 49.4. Matches aSDomain:
                     nrpspksdomains_CP976_RS38960_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:91422018"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1040: alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019068514.1"
                     /locus_tag="CP976_RS38960"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_38990"
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="WP_150484569.1"
                     /sec_met_domain="ADH_N (E-value: 1.3e-23, bitscore: 81.9,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.9e-24, bitscore:
                     82.9, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPTTTRAAVVESGGAPFTLSDVVLDEPGPHEALVRMVATGLCHTD
                     LGVASGGLPFPLPGVLGHEGAGVVEAVGSAVTGVTPGDHVLLSFTSCGDCRNCRGGHPA
                     YCATWLPLNLLGGSRADGTNTISRGGQTLGGHFFGQSSFAERALADERSLVKVDPDVPL
                     ESIAPLGCGVQTGVGAVWNVLKPDTGSTVVVLGAGAVGLSAVMAATLTPATRIVAVDRV
                     AERLSLATELGATHTVDTSGTDLASALAEITGGQGADGVVETTGNVGVLRQGVDALAAR
                     GTLVVVGAPPFGTEVALDVNGLLGGKRIVGLTLGDSETQTMIPALVRLVKDGRLPLHRL
                     IGTYPFGDIDRAVQDMRSGKTIKPVLTF"
     aSDomain        2237..3250
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP976_RS38960_PKS_ER.1"
                     /evalue="1.20E-15"
                     /label="CP976_RS38960_PKS_ER.1"
                     /locus_tag="CP976_RS38960"
                     /protein_end="362"
                     /protein_start="24"
                     /score="49.4"
                     /tool="antismash"
                     /translation="DEPGPHEALVRMVATGLCHTDLGVASGGLPFPLPGVLGHEGAGVV
                     EAVGSAVTGVTPGDHVLLSFTSCGDCRNCRGGHPAYCATWLPLNLLGGSRADGTNTISR
                     GGQTLGGHFFGQSSFAERALADERSLVKVDPDVPLESIAPLGCGVQTGVGAVWNVLKPD
                     TGSTVVVLGAGAVGLSAVMAATLTPATRIVAVDRVAERLSLATELGATHTVDTSGTDLA
                     SALAEITGGQGADGVVETTGNVGVLRQGVDALAARGTLVVVGAPPFGTEVALDVNGLLG
                     GKRIVGLTLGDSETQTMIPALVRLVKDGRLPLHRLIGTYPFGDIDRAVQDMRSGKTI"
     CDS_motif       2345..2383
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CP976_RS38960_0001"
                     /evalue="3.80E-03"
                     /label="PKSI-ER_m2"
                     /locus_tag="CP976_RS38960"
                     /protein_end="73"
                     /protein_start="60"
                     /score="10.3"
                     /tool="antismash"
                     /translation="LGHEGAGVVEAVG"
     gene            complement(3393..4343)
                     /db_xref="GeneID:91422019"
                     /locus_tag="CP976_RS38965"
                     /old_locus_tag="CP976_38995"
     CDS             complement(3393..4343)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (23-313). E-value: 4.9e-56.
                     Score: 182.1. Matches aSDomain:
                     nrpspksdomains_CP976_RS38965_PKS_ER.1"
                     /codon_start=1
                     /db_xref="GeneID:91422019"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004979474.1"
                     /locus_tag="CP976_RS38965"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_38995"
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="WP_190147033.1"
                     /sec_met_domain="ADH_N (E-value: 2.4e-09, bitscore: 36.0,
                     seeds: 66, tool: rule-based-clusters)"
                     /sec_met_domain="ADH_zinc_N (E-value: 8.4e-18, bitscore:
                     63.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQNTMRAISQDVLGGPEVLKEVEVERPAPRPNEVLVRVRAAGV
                     NPTDWKHRATGGFLGEPPFVLGWDVSGVVEAVGIGVAAFAPGDEVFGMLPYPYGHGSHA
                     EYVIAPVRALARKPAGIDHVQAGALPLVSLTAWQALVEHADLKSGQRVLIHAAAGGVGH
                     VAVQIAKARGAHVIGTASAGKHEFLREIGVDEAVDYRETDFTEAVKDVDVVLDTIGGDN
                     ALRSLRVLRPGGVVVSILPGGSDDFYKEAERLGARAVRMLVDADRTGMETIAELAETGR
                     LRATIAGTFPLAAAAEAHASGDTGRTTGKLVLVND"
     aSDomain        complement(3405..4274)
                     /ASF="ER configuration inconclusive"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP976_RS38965_PKS_ER.1"
                     /evalue="4.90E-56"
                     /label="CP976_RS38965_PKS_ER.1"
                     /locus_tag="CP976_RS38965"
                     /protein_end="313"
                     /protein_start="23"
                     /score="182.1"
                     /tool="antismash"
                     /translation="VEVERPAPRPNEVLVRVRAAGVNPTDWKHRATGGFLGEPPFVLGW
                     DVSGVVEAVGIGVAAFAPGDEVFGMLPYPYGHGSHAEYVIAPVRALARKPAGIDHVQAG
                     ALPLVSLTAWQALVEHADLKSGQRVLIHAAAGGVGHVAVQIAKARGAHVIGTASAGKHE
                     FLREIGVDEAVDYRETDFTEAVKDVDVVLDTIGGDNALRSLRVLRPGGVVVSILPGGSD
                     DFYKEAERLGARAVRMLVDADRTGMETIAELAETGRLRATIAGTFPLAAAAEAHASGDT
                     GRTTGKLVL"
     CDS_motif       complement(3837..3899)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CP976_RS38965_0001"
                     /evalue="1.70E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="CP976_RS38965"
                     /protein_end="169"
                     /protein_start="148"
                     /score="26.8"
                     /tool="antismash"
                     /translation="GQRVLIHAAAGGVGHVAVQIA"
     gene            4415..5359
                     /db_xref="GeneID:91422020"
                     /locus_tag="CP976_RS38970"
                     /old_locus_tag="CP976_39000"
     CDS             4415..5359
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422020"
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040615.1"
                     /locus_tag="CP976_RS38970"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39000"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_150484571.1"
                     /transl_table=11
                     /translation="MRRERVVVLALDGVYPFELGIPSRILGAADGRYEVLTCSVDGGPV
                     RTNADFGITVEHSPEALATADTVVIAPIAPAHLTDEVPGDVLAALALIRPGTRIVSICT
                     GAFVLAAAGLLDGRRATTHWQVADRFRRMFPHVDLDPDVLFVDDHPFLTSAGAASGVDI
                     CLHLVRKDHGSRLANTVARRCVVPPFRDGGQAQYIEQPVPEQGAASTAATRSWALERLG
                     EPLTLADLAGHARMSLRTFARRFHDEVGLSPGRWLIQQRVARARHLLESSDLTVDQIAG
                     RVGFATGASLRQHLSAAIGVTPQAYRRTFQTTR"
     misc_feature    complement(5375..5392)
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 19.59"
                     /tool="antismash"
     gene            5610..7340
                     /db_xref="GeneID:91422021"
                     /locus_tag="CP976_RS38975"
                     /old_locus_tag="CP976_39005"
     CDS             5610..7340
                     /codon_start=1
                     /db_xref="GeneID:91422021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576969.1"
                     /locus_tag="CP976_RS38975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39005"
                     /product="ATP-binding protein"
                     /protein_id="WP_150484572.1"
                     /transl_table=11
                     /translation="MELATPPPAARAPVAWYSWWLMPLGLGGGTVAATFMSSERLTTAV
                     AGVAATAAGAVCVRLLLRTRAQLHRAEGSFRTTQAEHNAQWQQHVAGLERKFSAERATL
                     ESQLTEQNAAYERHVADQSATYESQLADQSRAYEERLTEQARSYEAQLADQAEVWQEQL
                     THQLAAVARLADEQLPDAMEKLRSGEAIDDVLPTVNQCAKVSADLQAELRKLLRTALVG
                     LEAEFDRSTSAEQAVISIGNRIHVLTSKLRGRLHEMQGEHGRLPAVARGLMELDQELGP
                     ADSLAASIGVLGGSDRPGRQWQEPQRLLSVVRGGIGRIKDFHRVQVRHLPELGVDGGLV
                     DHLTLIFAHLLDNAARYSPPTEPVLISGKEVPNGVGIEIQDSGKGLSEEKKREAEHALA
                     GTAPGAGLGGITEDASIGLRVVGALARRYGIRVTFADSPWLGTSVVVVVPHKYFSPLPA
                     AATTQAAPAPEARPAAPAPVRDETVTAPAPAAESEVVETTPGGLPRRRSKRNETDGPGQ
                     AERSDRSTAVSAVPPDASFSGLAAFATAGRDAAEASRAADDRDTPAGREFTEHRTQESD
                     "
     gene            7346..7756
                     /db_xref="GeneID:91422022"
                     /locus_tag="CP976_RS38980"
                     /old_locus_tag="CP976_39010"
     CDS             7346..7756
                     /codon_start=1
                     /db_xref="GeneID:91422022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057749.1"
                     /locus_tag="CP976_RS38980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39010"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_003994857.1"
                     /transl_table=11
                     /translation="MTQQGTDVSWALRDLVESIQEIRFALVASSDGKAITSYGAEDPDD
                     VDRFAAVVAGLQALAQPVAEQFPKYAGQLRLAMIEVDGGHLFVVRAGVETYLGVLAREG
                     LDQGLLGHQMRDLARRMGELLGTTPRLEEHSG"
     gene            7753..8124
                     /db_xref="GeneID:91422023"
                     /locus_tag="CP976_RS38985"
                     /old_locus_tag="CP976_39015"
     CDS             7753..8124
                     /codon_start=1
                     /db_xref="GeneID:91422023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995719.1"
                     /locus_tag="CP976_RS38985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39015"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_010040608.1"
                     /transl_table=11
                     /translation="MSAPRRPSDPSGLERYYVLTGGRSGPGGSASSLDVATLVVARAAP
                     LPGMQHEHEEILRRCRDPLSVAELGAHLGLPFNILAVLLSDLLDAGRVEARDPIPAHDA
                     GRGPDLALLEEVLSGLERL"
     misc_feature    7888..7890
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8105..8710
                     /db_xref="GeneID:91422024"
                     /locus_tag="CP976_RS38990"
                     /old_locus_tag="CP976_39020"
     CDS             8105..8710
                     /codon_start=1
                     /db_xref="GeneID:91422024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156547.1"
                     /locus_tag="CP976_RS38990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39020"
                     /product="ATP/GTP-binding protein"
                     /protein_id="WP_150484573.1"
                     /transl_table=11
                     /translation="MDLKGFDQPGGRAAGDTRSVKVMIAGGFGTGKTTMVRSVSDIKPL
                     TTEETLTQASVDVDHLIGVADKTQTTVSLDFGKIGINESLVLYLFGTPGQERFWFLWNG
                     LFKGALGAIVLVDTRRLESSFRAIEEMERQDVPFVVALNVFPDSRNYPVEEIRDALDIP
                     EHTPVVAFDARDRASSRDVLVALIHHLKQRSAVALEPR"
     gene            8707..9957
                     /db_xref="GeneID:91422025"
                     /locus_tag="CP976_RS38995"
                     /old_locus_tag="CP976_39025"
     CDS             8707..9957
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422025"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576967.1"
                     /locus_tag="CP976_RS38995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39025"
                     /product="cytochrome P450"
                     /protein_id="WP_150484574.1"
                     /transl_table=11
                     /translation="MNDQTENGLQAVRGCPVAHHGTDLTRLYGPEAATDPGSIYERLRK
                     EHGSVAPVLLEGDVPAWLVLGYRDNRRVLDNPRQFSRDARIWRDWAQGRVEETSPLIPM
                     LGWRPDCVSQDGEPHRRLRSAVTDGLQAAATRGIRRHATHFANKQINAFADTGRADLVP
                     DYAEYLPMLVLSRILGLPEVEGRDLVESCAQVLKGGEDALAHNERIMLILGELAERKRT
                     EPGGDFTTALLGHAAGLDEEEVVSHLRLVLIAAHTTTSNLLARVLQLVLTDTARLSGLI
                     SGQLNISAVVEEVMWNSPPLAVLPGRFAAGDLELGGHQIQEGDLLVLGLAAGNVDPEIR
                     PDTGVSVQGNQAHLAFSSGPHECPGQSIGQSIIEIAVDVLLHRLPGLTLAVPPEELTST
                     ASTWESRLDSLPVEFPV"
     gene            complement(10001..11032)
                     /db_xref="GeneID:91422026"
                     /locus_tag="CP976_RS39000"
                     /old_locus_tag="CP976_39030"
     CDS             complement(10001..11032)
                     /EC_number="4.2.3.169"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422026"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040594.1"
                     /locus_tag="CP976_RS39000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39030"
                     /product="7-epi-alpha-eudesmol synthase"
                     /protein_id="WP_150484575.1"
                     /sec_met_domain="T1TS (E-value: 2.3e-72, bitscore: 243.6,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQDVRFDLPFDTPVSEHLEYARARHLRWVWEMRLVRSREGFEEY
                     KSWDLPQAAARTYPHASADDMVVLMNWFSLAFLFDDQFDASQPDRADRIAEVARELIVT
                     PLRPAGSPPRVACPITLAWAEVWNHLSHGMSLTWQTRFAASWGRFLVAHCEEVDLAARG
                     LEGTLGLDEYAEFRRRTVGIHHSIDAGERSRGFEVPAQAMGHPVMERMRDLAADTIGFM
                     NDIHSFEREKRRGDGHNLIAVLRRERGCSWQEATDEAYRMTIACLDEYLELQERVPQMC
                     DELRLDEAERDRVRMGVEAIQHWINGNYEWALTSGRYAAAKEGPVATAELAGRGSVDDL
                     LTV"
     misc_feature    complement(11090..11105)
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: weak, score: 15.8"
                     /tool="antismash"
     gene            11340..11804
                     /db_xref="GeneID:91422027"
                     /locus_tag="CP976_RS39005"
                     /old_locus_tag="CP976_39035"
     CDS             11340..11804
                     /codon_start=1
                     /db_xref="GeneID:91422027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994862.1"
                     /locus_tag="CP976_RS39005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39035"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_150484576.1"
                     /transl_table=11
                     /translation="MTSEPARSAEQRKKDTLHRLEHDVDAWVATADGTSGTPYLVPLSF
                     LWNGSYLLFATPASSPTGRNLAATGRARVGIGPTRDVVLVEGTVETVQPGELTEQDAEL
                     FAAKTGFDPRGLATPYLYFRVVPQRVQAWREANELDGRELMRAGRWLTAD"
     misc_feature    complement(11879..11889)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     gene            11884..12276
                     /db_xref="GeneID:91422028"
                     /locus_tag="CP976_RS39010"
                     /old_locus_tag="CP976_39040"
     CDS             11884..12276
                     /codon_start=1
                     /db_xref="GeneID:91422028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007386583.1"
                     /locus_tag="CP976_RS39010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39040"
                     /product="VOC family protein"
                     /protein_id="WP_150484577.1"
                     /transl_table=11
                     /translation="MALVKAGVLVLDCAEPEKLAVFYKELLEGEEADATANRVEIKGAD
                     GFRVALRRDVNATPPSWPRPENSLQAHLEFVVDDLDAVERRVISLGGRPLEAKDASGPL
                     EERGYADPAGHSFVLRRTPPTAPKQG"
     gene            complement(12412..12708)
                     /db_xref="GeneID:91422029"
                     /locus_tag="CP976_RS39015"
                     /old_locus_tag="CP976_39045"
     CDS             complement(12412..12708)
                     /codon_start=1
                     /db_xref="GeneID:91422029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040583.1"
                     /locus_tag="CP976_RS39015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39045"
                     /product="DUF4235 domain-containing protein"
                     /protein_id="WP_086565167.1"
                     /transl_table=11
                     /translation="MAKKKKLPFAYQPLGFVLGWSSGWLAGLAFRKTWMAIRNEEDAPD
                     ALDKDRGWGEILLAAAVQGAIFAVVRSAVDRAGAKAIERSTGTWPAGEKGGRD"
     gene            complement(12747..13772)
                     /db_xref="GeneID:91422030"
                     /locus_tag="CP976_RS39020"
                     /old_locus_tag="CP976_39050"
     CDS             complement(12747..13772)
                     /codon_start=1
                     /db_xref="GeneID:91422030"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GST_C"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978084.1"
                     /locus_tag="CP976_RS39020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39050"
                     /product="glutathione S-transferase C-terminal
                     domain-containing protein"
                     /protein_id="WP_150484578.1"
                     /sec_met_domain="GST_C (E-value: 1.1e-05, bitscore: 24.5,
                     seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRDDGDGGNSAYGRRSFKRSKAHFADRITADGRDGWPAEAGRYR
                     LVVSRACPWASRSLVSRRLLGLEDALSLAVADPIQDDRSWRFTLDEDGRDPVLGIRYLS
                     QAYDRRETDHPGGVSVPAMVDVPSGKLVTNDYQQITLDLATEWTALHREGAPDLYPLKL
                     RDEIDEVMADVYEDVNNGVYRAGFATEQEEYETACAGVFRRLELLADRLERQRYLVGDT
                     ITEADIRLFTTLVRFDAVYHGHFKCNRWKLTENRVLWGYARDLYQTPGFGDTVDFDHIK
                     RHYYQVHTGINPTRVVPLGPDLSGWLTPHHREELGGRPFGDGTPPGPVRAEERVPAAGT
                     P"
     gene            13807..14853
                     /db_xref="GeneID:91422031"
                     /locus_tag="CP976_RS39025"
                     /old_locus_tag="CP976_39055"
     CDS             13807..14853
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0006812 - monoatomic cation transport
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994866.1"
                     /locus_tag="CP976_RS39025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39055"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_229876413.1"
                     /transl_table=11
                     /translation="MSCVCPGERVPLFPPTARCEHRRPGQSAWVTAEGTDRRTRVTVLV
                     ALAANLVIAAAKAVGGLAAGSPALLSEAAHSVADSMNEVFLLAALRRSRRPADRRHPFG
                     YGKERFFWSLLAAVGIFVMGGCFSFFQGIEALVSGGEEKLGGYVAGLIVLGIALLAEGA
                     SLLRALYQVRRQGGTVAGLRDPALRTVVAEDGTAVLGVTLAIAGMALHMVTGQVVWEAS
                     ASLAIGALLVYVAYRLGRDARDQLIGEAADREASGRIRELLRAQPEIDSVEALFTMKTG
                     LDSALVAARVDLVPGLDSEHVEDVAVRIKRSIARTVPEADQIFLDVTDRRAQEAAESPA
                     ATGERGGA"
     misc_feature    14062..14064
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(15083..15313)
                     /db_xref="GeneID:91422921"
                     /locus_tag="CP976_RS44100"
     CDS             complement(15083..15313)
                     /codon_start=1
                     /db_xref="GeneID:91422921"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP976_RS44100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229876394.1"
                     /transl_table=11
                     /translation="MSTPSEPRQPHDGPALEPIRVLRPRRTDALAELMREYREEIGSAP
                     GGNEPRGNEFRLRVQPSGPAAGRKPALRAGR"
     gene            complement(15527..15976)
                     /db_xref="GeneID:91422032"
                     /locus_tag="CP976_RS39035"
                     /old_locus_tag="CP976_39065"
     CDS             complement(15527..15976)
                     /codon_start=1
                     /db_xref="GeneID:91422032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003978086.1"
                     /locus_tag="CP976_RS39035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39065"
                     /product="nitroreductase family deazaflavin-dependent
                     oxidoreductase"
                     /protein_id="WP_150484580.1"
                     /transl_table=11
                     /translation="MPLEGEYEPSPTQWVRKQVELYESSGGTEGTTLQGSKMPVVLLTS
                     RGVRSGKLRKTPVMRVEHEGRYAAVASLGGAPKHPVWYFNIKADPHVELQDGPVKQDMI
                     AREVTGQEKAEWWERAVAAYPAYADYQKKTDREIPVFVLEPADGG"
     gene            complement(16080..16712)
                     /db_xref="GeneID:91422033"
                     /locus_tag="CP976_RS39040"
                     /old_locus_tag="CP976_39070"
     CDS             complement(16080..16712)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040575.1"
                     /locus_tag="CP976_RS39040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39070"
                     /product="LysE family transporter"
                     /protein_id="WP_150484581.1"
                     /transl_table=11
                     /translation="MTTALLAGLLAGYGIAVPVGAVGTYLVSLTARTSLRTGVCAALGI
                     ATADGLYALAATLGGTALAGVLRPVLGPLRWVCVLVLLVLAVWGAVTAVREYRGHRLAT
                     RTAPAPPGPGRAYLGLLGITLLNPTTVIYFAALVLGSQATGPAGPLEQGVFVLAAFIAS
                     ASWQVLLAGSGALLGRALTGHRGRLGTALVASGVMTALAVRMALAPG"
     gene            17061..18257
                     /db_xref="GeneID:91422034"
                     /locus_tag="CP976_RS39045"
                     /old_locus_tag="CP976_39075"
     CDS             17061..18257
                     /codon_start=1
                     /db_xref="GeneID:91422034"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134806.1"
                     /locus_tag="CP976_RS39045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39075"
                     /product="cytochrome P450"
                     /protein_id="WP_150484582.1"
                     /sec_met_domain="p450 (E-value: 1.8e-27, bitscore: 95.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETTAPVAFPQSRTCPYQPPAAYDPLRGERPLTRITLFDGREAW
                     LVSGHATARALLADPRLSSNRSRPGFPAPTRRFAGITNRRTALLGVDDPEHRTQRRMVV
                     GDFTLKRAVELRPQIQQIVDERLDAMIAQGPPADLVTTFALPVPSMVICALLGVPYADH
                     DFFETQSRRLLRGPETADVEDARDRLEAYFGELIDHKQQDPGTGLLDDLVHRQLRDGAL
                     DRDGLTALALILLVAGHETTANMISLGTYTLLQHPERLAELRADPGLLPAAVEELMRML
                     SIADGLLRLAVEDIEVAGTTIRKGDGVVFATSVINRDETVYPDPDTLDWSRPARHHVAF
                     GFGIHQCLGQNLARAELEIALHTLFDRLPTLRLAAPAEEIPFKPGDTIQGMLELPVTW"
     gene            18270..18470
                     /db_xref="GeneID:91422035"
                     /locus_tag="CP976_RS39050"
                     /old_locus_tag="CP976_39080"
     CDS             18270..18470
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0009055 - electron transfer activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422035"
                     /gene_functions="other (smcogs) SMCOG1265: ferredoxin"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011027347.1"
                     /locus_tag="CP976_RS39050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39080"
                     /product="ferredoxin"
                     /protein_id="WP_086854839.1"
                     /transl_table=11
                     /translation="MHIDIDKDVCIGAGQCALTAPDVFTQDDDGYSALLPGREDGSGSP
                     LVREAARACPVSAITVSETVG"
     gene            complement(18478..19029)
                     /db_xref="GeneID:91422036"
                     /locus_tag="CP976_RS39055"
                     /old_locus_tag="CP976_39085"
     CDS             complement(18478..19029)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422036"
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016823401.1"
                     /locus_tag="CP976_RS39055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39085"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150484583.1"
                     /transl_table=11
                     /translation="MDSAVARERALDAAEELFYGRGVRSVGMDDVRGSSGVSLKRLYQL
                     FPAKEQLVEAYLERRDARWRGQLAEYVERYGEPRERILAVFDWLGRWFGEPDFRGCAWI
                     NAYGELGATSPRVAGQVRAHKRAFRDYLTSLVEAAGLPGPLAGQLFLLAEGAMVTAGVT
                     RSAEPAAEAREAARLLLEVA"
     misc_feature    19051..19064
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: medium, score: 20.48"
                     /tool="antismash"
     misc_feature    complement(19086..19099)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.95"
                     /tool="antismash"
     misc_feature    19096..19110
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: weak, score: 16.4"
                     /tool="antismash"
     gene            19124..19582
                     /db_xref="GeneID:91422037"
                     /locus_tag="CP976_RS39060"
                     /old_locus_tag="CP976_39090"
     CDS             19124..19582
                     /codon_start=1
                     /db_xref="GeneID:91422037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020134804.1"
                     /locus_tag="CP976_RS39060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39090"
                     /product="nuclear transport factor 2 family protein"
                     /protein_id="WP_150484584.1"
                     /transl_table=11
                     /translation="MTGRPPLPPFTRDTAAQKVQAAEDAWNTRDPHKVALAYSEDSVWR
                     NRDTFVTGRAGIAEFLTRKWEREQEYALRKDLWAFDGNRIAVRFQYECRDADGRWWRSY
                     GNELWEFDEHGLMTRREASINDVPIEERERRIFGPRPEPERGATLPVR"
     gene            19611..20147
                     /db_xref="GeneID:91422038"
                     /locus_tag="CP976_RS39065"
                     /old_locus_tag="CP976_39095"
     CDS             19611..20147
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422038"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Flavoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003994871.1"
                     /locus_tag="CP976_RS39065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_39095"
                     /product="flavoprotein"
                     /protein_id="WP_150484585.1"
                     /sec_met_domain="Flavoprotein (E-value: 5.1e-12, bitscore:
                     44.7, seeds: 143, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQPTRKPFLYVVVCAAGIAADVSKLITAAQERDWEVGVIATPV
                     AMNGFFDTAAVEAQTGRPIRSAWRTPGEPRPFPAPDAVVVAPATFNTVNKWAAGIADTL
                     ALGTLCEAAGLGVPIAVLPCVADALSSHPAYRDSLERLRGMGVRFGDPYSGEPKEDGGR
                     PEFGWERALDLVERG"
     misc_feature    complement(20807..20823)
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 16.18"
                     /tool="antismash"
ORIGIN
        1 cgccctgcaa gttaccctcc aacgggtgaa tttgagcatg ttcgattgac atatgtctct
       61 gaattgcggc cgagttggcc gaggttcgcg cggggggcgt acgcgggcgt gagtgccggc
      121 gtgttccccg gcgtgcgtcc cggcctacga cagggcgtgc caggccttgg cgagagcctg
      181 gcgaaactgc tcggtctggt gtgccgtgag gtcgcgcacc atccgctcct ccagctcccg
      241 gacgggcccg gcatgccgtg cgagcagctc ccggccggcg tcggtgagca ggatcagccg
      301 ctcgcggcgg ttgcggggat tgcgctcccg gcgcaccagc ccgcggccct ccagggagcg
      361 gacgaggtcg gcgatggact gcgcggtgac gaaggagtcg cgcgccagct gggccgccga
      421 cagtccgtcg tgtcgctcga gcacggtcag cgcggtgtac tggagagcgg ttataccgga
      481 gggtctgacc agctcgtcca gatgggagcg cacgacgagc tccacctgct tgaccatgta
      541 gagcagggaa gggggtgcct tggtcacctg tgcgtcgagc atggatgcag gctagaccat
      601 tgacaggaaa cctgtctgta atgagactgc gaaccaacag gaatcctgtt tattgaaaac
      661 ttggcgacga cgctgaggag tggcgatgac caccttcgag agggaacccg gccggctgtt
      721 cgtcggggga cagtggcgcg aggccgccga cggggcgcgc accgaggtgg tcgacccgtc
      781 ccggggcacg gtcgtcacca ccgtcgcgga ggcgggcccg gccgacgtcg acgcggccgt
      841 ccgggccgcg cgcgaggcct acgacgaggg cgcctggtcc ggtctgagcg gccgcgagcg
      901 gggccgggtg ctgcaccgcg tcgcccagct gatccgcgag aacgccgacg agatcgccgc
      961 gctggagagc ctcgacgtcg gcaagccgat cacactgtgc ggcgcggtcg acgtgacgaa
     1021 cgcggccaac gactacgagt acttcgcgaa cctcgcgcag agccaggacg gcgccctgcg
     1081 cgacaccccc atgaacgccc tcgcctacac caagcgcgag cccctcggtg tggtcgccgc
     1141 gatcaccccg ttcaacttcc cgctgatcct cgccggcagc aagatcggcc ccgcgctggc
     1201 ggccggcaac accgtcgtcc acaagcccgc cgacgagacc ccgctgagcg ccctctacat
     1261 ggcccggctc ttccaggagg cgggggtacc cgacggcgtg gtcaacgtcg tgaccggcag
     1321 cgggccggtg gccggcgagg cgctgctgcg ccaccgcggt gtcgacaaga tcgccttcac
     1381 cggctccacc gcgatcggcc ggcacgtggc gagcgtcgcc ggcgaggcgc tcaagcccgt
     1441 caccatggag ctcggcggga acgcggccca cctcgtcttc gaggacgccg acctggagaa
     1501 ggcggtcggc gcggtcatca agggcttcgt cttcaacacc ggccagttct gcatgggcgg
     1561 cccgcgcctg ctggtcgccc gctcggtgta ccccacgctg ctcggcatcc tcgccgaggc
     1621 cgtacccggt gtgccggtcg gcgacccgcg cgacccggcc acggtcatcg gcccgatggc
     1681 ggccgagaag cacctgaaga aggtcgagga gtacgtcgcc ctggcccgca aggagggcgc
     1741 ccggatcgtc tgcggcggcg aacggctcga cctggacggc ggctactact accggcccac
     1801 cgtcatcgcc gacctgtcga acgactcccg cgtgatccag gaggagatct tcgggccggt
     1861 cctcaccgtg cagcccttcg acgacgagga cgaggccgtc gccctcgcca actccacccc
     1921 ctacggcctg gcctcgggcg tccagaccac caacctcgcc cgcgcgcacc gggtcgccga
     1981 ccggctccag gccggcatcg tctgggtcaa cgactgggcg atgctcgacc ccgcggtgcc
     2041 cttcggcggc gtgaaggact ccggctacgg ccgcgagtac gggcccgaag ccctcgccgg
     2101 ttacaccaag gtcaagtccg tcgtcgtctc gctcgactga gacagtcgtc aaggagctct
     2161 tgcgatgccc accaccaccc gtgccgcggt cgtcgagtcc ggcggcgcgc ccttcaccct
     2221 ctccgacgtc gtcctcgacg aacccggccc gcacgaggcg ctggtccgca tggtcgccac
     2281 cggcctgtgc cacaccgacc tcggtgtggc gagcggcgga ctgcccttcc cgctgcccgg
     2341 ggtcctcggc cacgagggcg cgggcgtcgt cgaggccgtc ggctccgccg tcaccggcgt
     2401 cacgcccggc gaccacgtcc tgctctcctt cacctcctgc ggcgactgcc gcaactgccg
     2461 cggcgggcac cccgcgtact gcgcgacctg gctgccgctg aacctgctcg gcggcagccg
     2521 ggccgacggc acgaacacca tcagccgcgg gggtcagacc ctgggcgggc acttcttcgg
     2581 ccagtcctcc ttcgcggagc gggcgctggc cgacgagcgc agcctcgtca aggtcgaccc
     2641 ggacgtgccg ctggagtcca tcgccccgct gggctgtggg gtgcagaccg gtgtgggtgc
     2701 cgtctggaac gtcctgaagc cggacacggg cagcacggtc gtcgtcctgg gcgccggggc
     2761 ggtcggtctg tcggccgtga tggcggctac cctcaccccg gccacgcgga tcgtcgccgt
     2821 cgaccgggtc gccgagcgcc tctccctggc gacggagctg ggcgccacgc acaccgtcga
     2881 cacgagcggg acggacctcg cctcggccct cgccgagatc accggcggcc agggcgcgga
     2941 cggtgtcgtg gagaccacgg gcaacgtcgg cgtcctgcgc cagggcgtcg acgcgctcgc
     3001 cgcccgcggc acgctggtcg tggtcggcgc cccgccgttc ggcaccgagg tcgccctgga
     3061 cgtcaacggg ctgctcggcg gcaagcggat cgtgggtctc accctcggcg acagcgagac
     3121 ccagaccatg atccccgcgc tggtccgtct ggtgaaggac ggccggctgc cgctgcaccg
     3181 gctgatcggt acgtatccct tcggggacat cgaccgggcg gtccaggaca tgaggtcggg
     3241 caagacgatc aagccggtgc tgacgttctg acgcggcggg ccgtcatagc cggttcgcat
     3301 cagagctcgg gggcgcggtg gatcggcgtg tgcggctgag ccgtggcctg tcgcgcagtt
     3361 ccccgcgccc cttcggggca ctgccgtccg ggtcagtcgt tcaccaggac cagcttcccc
     3421 gtcgtccggc ccgtgtcgcc cgaggcgtgg gcctccgcgg cggcggccag cgggaaggtg
     3481 ccggcgatcg tggcgcggag cctgccggtc tcggccagtt ccgcgatcgt ctccatgccg
     3541 gtgcggtcgg cgtcgaccag catccggacc gctcgtgcac cgagccgctc ggcctccttg
     3601 tagaagtcgt ccgaaccacc cggcaggatc gacaccacga ccccgcccgg gcgcagcacg
     3661 cgcagtgaac gcagcgcgtt gtcgccgccg atcgtgtcca ggacgacgtc gacgtccttc
     3721 acggcctcgg tgaagtcggt ctcccggtag tccaccgcct cgtccacgcc gatctcccgc
     3781 aggaactcgt gcttgcccgc gctcgcggtg ccgatcacat gggcgccgcg cgccttcgcg
     3841 atctgcaccg ccacatgccc gaccccgccc gccgcggcgt ggatcagcac ccgctgcccg
     3901 gacttcaggt ccgcgtgctc gacgagcgcc tgccacgcgg tcagcgacac caacggcagc
     3961 gcgcccgcct ggacgtggtc gatcccggcc ggcttgcgtg ccagggcccg caccggggcg
     4021 atgacgtact cggcgtgcga gccgtgcccg tacggatagg gcagcatgcc gaagacctcg
     4081 tccccgggtg cgaacgccgc gacgccgatg ccgaccgcct ccaccacccc ggagacgtcc
     4141 cagccgagga cgaagggcgg ctcgcccagg aagccgcccg tggcgcggtg cttccagtcg
     4201 gtcgggttga ccccggcggc ccgcacccgg accagcacct cgttcggcct gggcgccggg
     4261 cgctcgactt ccacttcctt caggacctcg ggaccgccga ggacgtcctg gctgatggct
     4321 cgcatcgtgt tctgtgtgct catggtcatc cagcgtgccc gcccgcgccc ggcccgccaa
     4381 tggcagaatg gtcaaccttc gataggatcg tgccatgcga cgtgagcgag tggtggtcct
     4441 ggccctggac ggcgtgtacc cgttcgagct gggcatcccc agccggatcc tgggcgcggc
     4501 cgacggccgg tacgaggtgc tgacctgctc ggtcgacggc ggtccggtgc gtacgaacgc
     4561 ggacttcggc atcaccgtgg agcacagccc cgaggccctg gccaccgccg acaccgtggt
     4621 tatcgcgccc atcgcccccg cccacctgac cgacgaggtg cccggcgatg tcctggccgc
     4681 gctcgccctc atacgccccg ggacgcgcat cgtctccatc tgcaccggcg ccttcgtcct
     4741 cgccgccgcc gggctcctcg acgggcgcag ggcgaccacc cactggcagg tcgccgaccg
     4801 gttccggcgc atgttcccgc atgtcgacct cgacccggac gtgctgttcg tcgacgacca
     4861 ccccttcctc acctccgcgg gagccgcctc cggcgtggac atctgcctgc acctggtccg
     4921 caaggaccac ggcagccggc tggccaacac cgtcgcccgc cgctgcgtgg tcccgccgtt
     4981 ccgggacggc ggccaggccc agtacatcga acagcccgtc cccgaacagg gcgccgcgag
     5041 caccgcggcc acccgctcct gggccctgga acgcctcggc gaaccgctca ccctggccga
     5101 cctcgccggc cacgcccgga tgagcctgcg caccttcgcc cgccgcttcc acgacgaggt
     5161 gggcctcagt cccggccgct ggctcatcca gcagcgggtg gcccgcgccc ggcatctgct
     5221 ggagtccagc gacctcacgg tggaccagat cgcgggccgg gtcggcttcg cgaccggcgc
     5281 ctccctgcgc cagcatctga gcgcggcgat cggggtgacc ccgcaggcct accgccgcac
     5341 gttccagacc acgcgctgac caggcagggc ccggtctccg ctcaactggg cagcgagcaa
     5401 agccatttgt cgacctgttg cttcctgtcg gagcgtgacg gaaccctcac gtccgccggg
     5461 ggacgaggtt gatcctctcg ggtgtaaacc cgataaggtt cccatcggcg ctgcgagttg
     5521 gcgcgatcgc gtccagtcga ctcgcagtgc gtactcatga gtgcggtccg cacacccccc
     5581 attcgatcgt gttgcttcga aggatgcaga tggaactcgc cactccgcca ccggcggcgc
     5641 gggcccctgt cgcctggtac agctggtggt tgatgccgct gggcttggga ggcgggacgg
     5701 ttgccgccac gttcatgagc tcggagcgac taaccacggc cgtcgccggt gtcgcggcga
     5761 cggcggccgg tgccgtgtgc gtgcgcctgc tgctgcgcac ccgggcccaa ctgcaccggg
     5821 cagagggctc ctttcgcacc acgcaggccg agcacaacgc gcagtggcag cagcacgtcg
     5881 cgggcctgga acggaagttc tccgccgagc gcgccaccct ggagtcgcag ctcaccgagc
     5941 agaacgcggc ctacgaacgg cacgtcgccg accagagcgc cacgtacgag tcgcagctcg
     6001 ccgaccagtc ccgggcgtac gaggaacggc tgaccgagca ggccaggtcc tacgaggccc
     6061 agctcgccga ccaggccgag gtctggcagg agcagctcac ccaccagctc gccgcggtcg
     6121 cccggctcgc cgacgagcaa ctgcccgacg cgatggagaa gctgcgctcc ggcgaggcca
     6181 tcgacgacgt cctgccgacc gtcaaccagt gcgcgaaggt cagcgccgac ctccaggcgg
     6241 aactgcgcaa gctcctgcgc accgccctgg tcggcctgga ggcggagttc gaccgctcca
     6301 cctccgccga gcaggccgtg atcagcatcg gcaaccgcat ccacgtgctg accagcaagc
     6361 tccgcggccg gctgcacgag atgcagggcg agcacggcag gctcccggcc gtcgcccgcg
     6421 gcctgatgga gctcgaccag gaactcggcc ccgccgactc gctcgccgcg agcatcggtg
     6481 tgctcggcgg ctcggaccgt ccgggacgcc agtggcagga accgcagcgg ctgctgagcg
     6541 tggtgcgcgg cggcatcggc cggatcaagg acttccaccg cgtccaggtg cgccacctgc
     6601 ccgaactcgg cgtcgacggc ggcctggtgg accacctcac gctgatcttc gcccacctcc
     6661 tggacaacgc ggcccgctac tcgccgccca ccgagccggt gctcatctcc ggcaaggagg
     6721 tccccaacgg cgtcggcatc gagatccagg actccggcaa gggcctgagc gaggaaaaga
     6781 agcgcgaggc cgaacacgcc ctcgccggca ccgcgcccgg cgccggcctc ggcggtatca
     6841 ccgaggacgc gagcatcggt ctgcgcgtcg tcggagccct cgcccgccgc tacggcatcc
     6901 gtgtcacctt cgcggactcg ccgtggctcg gcacctccgt ggtggtcgtg gttccgcaca
     6961 agtacttcag cccgctgccc gcggccgcga ccacccaggc cgcgcccgcc ccggaggccc
     7021 gccccgccgc gcccgccccg gtccgcgacg agacggtcac cgcaccggca ccggccgcgg
     7081 agtccgaggt cgtggagacc acccccggcg ggctgccccg gcgccgcagc aagcggaacg
     7141 agacggacgg gcccgggcag gccgagcgga gcgaccggag cacggccgtc tccgccgtcc
     7201 cgccggacgc ctccttctcc ggcctcgcgg ccttcgccac cgccggccgc gacgccgcgg
     7261 aggcgtcccg ggcggccgac gaccgcgaca ctcccgccgg acgcgagttc acagagcacc
     7321 gcacccaaga gagcgactag tcctcatgac gcagcaagga acagatgtga gctgggcgct
     7381 ccgcgatctc gtcgagagca tccaggagat ccgtttcgcc ctggtggcct ccagcgacgg
     7441 caaggccatc acctcctacg gcgccgaaga ccccgacgac gtcgaccgct tcgccgccgt
     7501 ggtggccggc ctccaggcgc tggcccagcc ggtcgccgag cagttcccca agtacgccgg
     7561 gcagctgcgc ctcgcgatga tcgaggtcga cggcgggcac ctcttcgtcg tccgggccgg
     7621 tgtggagacg tacctcgggg tcctcgccag ggagggcctc gaccagggcc tgctcgggca
     7681 ccagatgaga gacctggccc gcaggatggg tgagcttctc ggcaccactc cgcgcctgga
     7741 ggagcactct ggatgagtgc tccccgcagg ccgtccgacc cgtccggtct cgagcgctac
     7801 tacgtcctca ccggaggacg cagcggaccg ggcggttcgg cgtcgagcct cgacgtggcg
     7861 accctcgtcg tcgcccgagc cgccccgtta ccgggtatgc agcacgagca cgaggagatc
     7921 ctccgccgct gccgcgatcc gctgtcggtc gccgaactcg gcgcccacct cgggctgccc
     7981 ttcaacattc tcgccgtgct gctgtcggac ctgctggacg caggtcgcgt cgaagcccgc
     8041 gaccccatcc cggcacacga cgccggccgc gggcccgacc tcgcgctcct tgaggaggta
     8101 ctcagtggac ttgaaaggct ttgaccaacc cggagggcgg gcggccgggg acacccgctc
     8161 ggtgaaggtg atgatcgccg gcgggttcgg caccgggaag accaccatgg tccggtcggt
     8221 cagcgacatc aagccgctca ccaccgagga gaccctcacc caggccagcg tcgacgtcga
     8281 ccacctcatc ggcgtcgccg acaagacgca gaccaccgtc agcctggact tcggcaagat
     8341 cggcatcaac gagagcctgg tgctctacct gttcggcacg ccgggccagg agcggttctg
     8401 gttcctgtgg aacgggctgt tcaagggcgc gctcggcgcg atcgtcctgg tggacacgcg
     8461 ccgcctggaa tccagtttcc gggcgatcga ggagatggag cggcaggacg tcccgttcgt
     8521 cgtcgcgctg aacgtcttcc ccgactcccg gaactacccg gtcgaggaga tcagggacgc
     8581 actggacatc cccgagcaca ccccggtcgt ggccttcgac gcccgcgacc gggcctccag
     8641 ccgtgacgtc ctcgtcgccc tgatccacca cctgaaacaa cgctcggccg tggccctgga
     8701 gccccgatga acgatcagac cgaaaacggc ctccaggccg tgcgaggctg ccccgtcgcc
     8761 caccacggga ccgacctgac ccggctgtac gggccggagg cggcgaccga cccggggagc
     8821 atctacgagc ggctgcgcaa ggaacacggc tccgtcgcac cggtactgct cgaaggcgat
     8881 gtgccggcct ggctcgtcct cggctaccgc gacaaccggc gggtgctcga caacccccgc
     8941 cagttcagcc gggacgcgcg catctggcgg gactgggcac aggggcgcgt ggaggagacc
     9001 tcgccgctga tcccgatgct cggctggcgg cccgactgcg tgtcccagga cggcgagccg
     9061 caccgcaggc tgcggtccgc cgtcaccgac ggactccagg cggccgcgac ccggggcatc
     9121 cggcgccacg cgacccactt cgcgaacaag cagatcaacg cgttcgcgga caccggacgc
     9181 gccgacctcg tcccggacta cgccgagtac ctgccgatgc tcgtcctctc ccgcatcctc
     9241 gggctgcccg aggtggaggg ccgggacctg gtcgagtcct gcgcccaggt cctcaagggc
     9301 ggtgaggacg ccctcgcgca caacgagcgc atcatgctga tcctcgggga actggccgag
     9361 cgcaagcgga ccgaacccgg tggcgacttc accaccgccc tgctggggca cgcggccggc
     9421 ctcgacgagg aggaggtggt cagccatctg cgtctggtgc tgatcgccgc ccacaccacg
     9481 accagcaacc tgctggcccg ggtcctccag ctcgtcctca ccgacaccgc ccggctctcc
     9541 ggactgatca gcgggcagct gaacatctcg gccgtggtgg aggaggtcat gtggaacagc
     9601 cccccgctgg ccgtgctgcc gggccggttc gccgccggcg acctggaact cggcggccac
     9661 cagatccagg agggcgacct gctggtcctc ggcctcgcgg cgggcaacgt cgaccccgag
     9721 atccggccgg acaccggcgt ctcggtccag ggcaaccagg cccatctggc gttcagttcc
     9781 ggtccgcacg agtgccccgg gcagagcatc ggccagtcca tcatcgagat cgccgtggac
     9841 gtgctgctgc accgcctgcc gggcctgacc ctggccgtgc ccccggagga gctcacctcg
     9901 accgcctcca cgtgggagtc acggctggac agcctgccgg tcgagttccc ggtctgacga
     9961 ggatgcccgg ccggacaccg gccgggcacc accccgttcc tcacacggtc agcaggtcgt
    10021 ccaccgagcc ccgcccggcc agttccgccg tcgccacggg gccctccttc gccgccgcgt
    10081 agcggccgct ggtcagcgcc cactcgtagt tgccgttgat ccagtgctgg atggcctcga
    10141 cccccatccg cacccggtcc cgctccgcct cgtcgagccg caactcgtcg cacatctgcg
    10201 ggacgcgctc ctggagttcg aggtactcgt cgagacaggc gatcgtcatc cggtacgcct
    10261 cgtccgtggc ctcctgccag gagcagcccc gctcccggcg cagcacggcg atgaggttgt
    10321 ggccgtcgcc gcgccgcttc tcgcgctcga aggagtggat gtcgttcatg aacccgatgg
    10381 tgtccgcggc cagatcacgc atccgctcca tcaccggatg tcccatcgct tgtgccggca
    10441 cctcgaagcc gcggctgcgc tcgcccgcgt cgatgctgtg gtggatgccg accgtacggc
    10501 gccggaactc ggcgtactcg tcgagcccca gcgtgccctc caggccccgg gccgccaggt
    10561 cgacctcctc gcagtgcgcg accaggaacc gcccccacga ggcggcgaaa cgcgtctgcc
    10621 atgtcaggga catgccatgc gagaggtggt tccacacctc cgcccaggcg agagtgatcg
    10681 gacaggccac acggggaggg ctgccggccg gccgcagggg agtgacgatc agttcccgtg
    10741 cgacctccgc tatgcggtcg gcgcggtccg gctgactggc gtcgaactgg tcgtcgaaga
    10801 ggaaggccag tgagaaccag ttcatcagga cgaccatgtc gtccgccgac gcgtgcggat
    10861 aggtgcgggc ggccgcctgg ggcaggtccc aggacttgta ctcctcgaac ccctcccggc
    10921 tgcggaccag gcgcatctcc cacacccagc gcagatgacg tgcccgggcg tactccagat
    10981 gctcgctgac cggggtgtcg aaggggaggt cgaaccggac gtcctgaggc atgggcttcc
    11041 tttcgggaga cggaccgcag agccccccgc ccctgcgagc ggacggtgcc gtgaccgtcc
    11101 gcacactcga actcggcttc acagtccgaa agttgaaccg agaagcggta cgagactgcc
    11161 caaggcgcga atcagccatt ccgtgaccct gccgtgatct ccgttactgc ccgaaccgca
    11221 tgagctgcgt atactccctc gtccctcacc cggcatcggc ttgtccaccg tgcctccgca
    11281 gcctcggaac gtcacactgg tagacgtcag ttgacgacgc ttcaggagga ttgccgacga
    11341 tgacgtccga acccgcacgc agcgctgagc agcgcaagaa ggacaccctg caccgcctgg
    11401 agcacgacgt ggacgcctgg gtcgccacgg ccgacggcac gtccgggacg ccgtacctcg
    11461 tcccgctgtc cttcctctgg aacggctcgt acctgctgtt cgccaccccc gcgtcgagcc
    11521 ccaccggacg gaatctggcc gcgaccggcc gggcccgcgt cggaatcggg ccgacccgtg
    11581 acgtcgtgct cgtcgagggc accgtggaga ccgtccagcc cggcgagctg accgagcagg
    11641 acgccgaact cttcgccgcc aagaccgggt tcgacccccg cgggctggcc acgccgtacc
    11701 tctacttccg cgtcgtgccg cagcgggtgc aggcctggcg ggaggccaac gaactggacg
    11761 gccgcgaact catgcgcgcc ggacggtggt tgacggccga ctgaatcggc cggaccggga
    11821 tatccgcaag gtacagggcc gcggggcacg accgccccgc ggccggaatc ctgcggagga
    11881 gacatggcac tggtgaaagc gggtgtcctg gtgctcgact gtgccgagcc cgagaaactc
    11941 gccgtgttct acaaggagct gctggaaggg gaagaggcgg acgcgaccgc caaccgggtg
    12001 gagatcaagg gcgcggacgg cttccgcgtc gccctgcgcc gggacgtcaa cgcgacaccg
    12061 cccagctggc cccgcccgga gaactccctc caggcgcacc tggaattcgt ggtggacgac
    12121 ctcgacgcgg tggaacgccg ggtcatctcc ctcggcggcc gccccctgga ggccaaggac
    12181 gcctcgggcc ccctggagga gcggggctac gccgacccgg caggccactc cttcgtcctg
    12241 cgccgcaccc caccgaccgc gcccaaacag ggctgaccgg aggcggcggg ccggttgccg
    12301 gcggccctcc cgcgatctcc gtacgggcaa cgatcgacat ctgaggggcg cggcggcccc
    12361 gcacaggccg gccccgcccc gccgcaccgg cggggcgggg ccgcgtcgtt ctcagtcgcg
    12421 gccgcccttc tccccggccg gccacgtgcc ggtggaacgc tcgatcgcct tggcgcccgc
    12481 gcggtccacc gcgctgcgca ccacggcgaa gatggcgccc tggaccgcgg cggccagcag
    12541 gatctcgccc cagccgcggt ccttgtccag cgcgtcggga gcgtcctcct cgttccggat
    12601 cgccatccac gtcttgcgga aggccagccc ggccagccag ccgctcgacc agcccagcac
    12661 gaacccgagg ggctggtagg cgaagggaag cttcttcttc ttggccacgc gaatctcctt
    12721 gatcggtgag ggtgggtgga aagtggtcag ggtgtgcccg cggccgggac ccgctcctcg
    12781 gcgcggaccg gcccgggcgg cgtgccgtca ccgaacggcc ggccgcccag ctcctcgcgg
    12841 tggtgcgggg tcagccagcc ggacaggtcc gggcccagcg gcacgacgcg ggtcgggttg
    12901 atgcccgtgt gcacctggta gtagtggcgc ttgatgtggt cgaagtcgac ggtgtcgccg
    12961 aacccgggcg tctgatagag gtcacgggca tagccccaca gcaccctgtt ctccgtcagc
    13021 ttccagcggt tgcacttgaa gtggccgtgg tagaccgcgt cgaaacggac cagcgtggtg
    13081 aacagccgga tgtccgcctc ggtgatggtg tcgccgacga ggtaccgctg ccgctccagc
    13141 cggtccgcga gcagctccag ccgccggaag acgcccgcgc aggcggtctc gtactcctcc
    13201 tgttcggtgg cgaaacccgc ccggtacacg ccgttgttga cgtcctcgta gacgtccgcc
    13261 atcacctcgt cgatctcgtc gcgcagcttc agcggataca ggtcgggcgc gccctcccgg
    13321 tgcagcgccg tccactcggt cgcgaggtcg agcgtgatct gctggtagtc gttggtgacc
    13381 agcttcccgc tgggcacgtc caccatcgcc ggcacgctga caccgcccgg gtggtccgtc
    13441 tcccgccggt cgtaggcctg gctgaggtag cggatgccga ggaccgggtc gcggccgtcc
    13501 tcgtccagtg tgaagcgcca gctgcggtcg tcctggatcg ggtcggcgac ggccagggac
    13561 agcgcgtcct ccaggccgag cagccgccgg gagaccagcg accggctcgc ccacgggcag
    13621 gcgcggctga cgaccagacg gtagcggccg gcctccgccg gccagccgtc ccggccgtcg
    13681 gcggtgatcc ggtccgcgaa atgcgccttg gaccgtttga acgacctcct cccgtaggcg
    13741 ctgttgccgc cgtcgccgtc gtcgcggctc atggggatga cctccttcgg catacgtgtg
    13801 gcctgcttgt cgtgcgtgtg ccctggtgaa cgcgttcccc tttttccgcc gacggcacgg
    13861 tgtgagcacc gccgaccggg gcaatcggcg tgggtgactg cagaaggaac tgatcggagg
    13921 acacgcgtca ccgtgctggt ggcgctcgcc gccaatctgg tgatcgcggc ggcgaaggcg
    13981 gtcggcggcc tggccgcggg atcgccggcg ctgctgtcgg aggcggccca ctcggtggcc
    14041 gacagcatga acgaggtgtt cttactggcg gcactgcgcc gcagccgccg ccccgccgac
    14101 cggcgtcacc ccttcggcta cggcaaggag cggttcttct ggtcgctcct cgcggccgtc
    14161 gggatcttcg tcatgggcgg gtgcttctcc ttcttccagg gcatcgaggc cctggtgagc
    14221 ggcggggagg agaaactcgg cggctatgtc gccggtctga tcgtgctcgg catcgccctc
    14281 ctcgcggagg gcgcctctct gctgcgggcg ctgtaccagg tgcgccggca gggcggcacg
    14341 gtcgccgggc tgcgcgaccc cgccctgcgc acggtcgtcg ccgaggacgg caccgcggtg
    14401 ctcggcgtca cgctggccat cgccggcatg gcgctgcaca tggtcacggg ccaggtggtg
    14461 tgggaggcgt ccgcctccct ggcgatcggc gcgctgctgg tctacgtcgc ctaccggctg
    14521 ggccgtgacg cccgcgacca gctgatcggc gaggcggccg accgggaggc gagcgggcgg
    14581 atccgggagc tgctgcgggc acagccggag atcgacagcg tggaggcgct gttcaccatg
    14641 aagacgggcc tcgactcggc cctcgtggcc gcccgcgtcg acctcgtgcc cggcctggac
    14701 agcgagcacg tcgaggacgt cgccgtccgc atcaagcgct ccatagcccg gacggtgccc
    14761 gaggccgacc agatcttcct cgacgtcacc gaccgtcgcg cgcaggaggc agcggaaagc
    14821 cccgccgcga cgggggaacg cggcggggcc tgaccctcgc gtgccccgtc gcggacggtt
    14881 catgcagcgc cccggagaag ttttttcgcc gaccacccga cagggtggtc ggcttgggct
    14941 gtccggcccg ctccggtcgt cgctccgggc gggtcccgag ggaccgacca cggagcgcgc
    15001 ccgacgtcca gggcgccggc cggacgggcg gtggccgctt cgccctctgc ggccggagac
    15061 atggcgcctg gacggcgaac cgctaccggc ctgcccgaag ggctggcttc cgcccggcgg
    15121 ctggcccgga gggctggact cgtagccgaa actcgttgcc gcggggctcg ttgccgcccg
    15181 gggccgagcc gatctcctcg cggtactccc gcatcagttc cgcgagtgcg tcggtgcggc
    15241 gaggccgcag gacgcggatg ggttcgaggg ccggtccgtc gtgcggctgc cggggctcgg
    15301 acggtgtcga cacgctgctc tccttccgtc cgggctcggg ggcgcccgtc ttcggggtcg
    15361 cgttgccccg gccgccggcc ggctccgatc cgcccggcgg cttgcccgga gggctgacct
    15421 ccgcccggcg gctggcccga agtgcgccct ccgcccggcg gcctggccga agggcggcct
    15481 ccgcccggcc ggaatcaccc cgggcccgcc cgaagccccc ggggactcac cccccgtcag
    15541 ccggctccag cacgaacacc ggtatctccc ggtccgtctt cttctggtag tcggcgtagg
    15601 ccggatacgc cgcgacggcg cgctcccacc actcggcctt ctcctggccc gtgacctcgc
    15661 gggcgatcat gtcctgcttg accggaccgt cctggagctc cacgtgcgga tcggccttga
    15721 tgttgaagta ccagaccggg tgcttgggcg cgccaccgag cgaggcgacc gcggcgtaac
    15781 gcccctcgtg ctccacccgc atcaccggtg tcttgcgcag cttgccgctc ctgacgcccc
    15841 gtgaggtcag gaggaccacc ggcatcttcg agccctggag cgtcgtcccc tccgtaccgc
    15901 cggagctctc gtacagttcc acctgcttgc gcacccactg cgtcgggctg ggttcgtact
    15961 cgccctcgag aggcatggca tccgtcccat cgtcgcgtca cggctgactg gcacccggat
    16021 tcaacaccgg tacgcccccg aatcatccgc accgcggcac atcgagccgg ccgggcacct
    16081 caccccggcg ccagcgccat ccgcacggcc agagccgtca tgaccccgct cgccaccagc
    16141 gccgtcccca gccggccccg gtgaccggtc agcgcccgcc ccagcagggc cccgctcccg
    16201 gcgagcagca cctgccagct cgcggaggcg atgaaggcgg cgagcacgaa gacgccctgc
    16261 tccagcgggc cggccgggcc agtcgcctgg gagccgagca cgagcgccgc gaagtagatc
    16321 acggtggtgg ggttcagcag ggtgatgccg agcagcccca ggtaggcccg gccgggtccc
    16381 gggggagcgg gggccgtccg cgtggccagc cggtggccgc ggtactcccg cacggcggtg
    16441 accgcgcccc acaccgccag cacgagcagc accaggacac agacccaccg cagcggcccg
    16501 agcaccggcc gcaacacgcc ggccagggcc gttcccccga gcgtggccgc gagggcgtac
    16561 agcccgtcgg cggtcgcgat gccgagcgcg gcacagacac cggtgcgcag ggacgtgcgg
    16621 gcggtgaggg agaccaggta cgtcccgacc gcgccgacgg ggacggcgat gccgtatccg
    16681 gcgagcagcc ccgcgaggag cgcggtcgtc atgaccgcgg cgcggtcggc cctccacggt
    16741 gtccggacgg ctgctgtcgg cgcgtggcag gagcggcggc ggacagcggc agatggacgg
    16801 cgaacgtagg catggctgga tcctggggcc tgtcccgtcc cgccgacaac cggttttcga
    16861 accggcaccg ccgcgccccg gcgtccggcg agggccaagc ctcgcacccg gctcccgacg
    16921 cccggcgttc gaactggaag acggcattcc tcggccatgt tgcaccgtgc gccgatctgg
    16981 ccgaacttcg cgtcgcccca tagatgcccg aggcatctaa tgaagatcgg cacgacgcat
    17041 acttcgtctg cgaggtcttc atgacggaaa cgaccgcacc cgtcgccttc ccccagagcc
    17101 ggacctgccc ctatcagccg cccgccgcct acgatccgct gcgcggcgag cgccccctga
    17161 cccgtatcac cctcttcgac ggccgtgagg cgtggctggt cagcgggcac gcgaccgccc
    17221 gcgcgctgct cgccgacccg cgcctgtcct ccaaccgcag ccgccccggc ttccccgccc
    17281 cgacccggcg gttcgccggg atcacgaacc gcagaacggc cctgctgggc gtcgacgacc
    17341 ccgagcaccg cacccagcgg cggatggtcg tcggcgactt caccctcaaa cgggccgtcg
    17401 aactccggcc gcaaatccag cagatcgtcg acgagcggct cgacgcgatg atcgcccagg
    17461 gcccgcccgc ggacctggtg accaccttcg cgctgcccgt gccgtccatg gtgatctgcg
    17521 ccctgctcgg cgtcccgtac gccgaccacg acttcttcga gacgcagtcg cgacggctgc
    17581 tgcgcggccc ggagaccgcc gacgtggagg acgcccgcga ccggctggag gcgtacttcg
    17641 gcgagctgat cgaccacaag cagcaggacc ccggcaccgg cctgctggac gacctcgtcc
    17701 accggcagct tcgcgacggc gcgctcgacc gcgacggcct gaccgccctg gcgctcatcc
    17761 tgctggtcgc gggccacgag acgaccgcca acatgatctc gctcggcacc tacaccctgc
    17821 tccagcaccc cgagcggctc gccgagttgc gcgccgaccc ggggctgctt ccggccgcgg
    17881 tcgaggagct gatgcggatg ctgtcgatcg ccgacggtct gctgcgcctg gccgtcgagg
    17941 acatcgaggt ggccgggacg accatccgca agggggacgg cgtggtcttc gcgacctccg
    18001 tcatcaaccg cgacgagacg gtctaccccg atccggacac gctcgactgg agccgcccgg
    18061 cccggcacca cgtcgccttc ggcttcggca tccaccagtg cctcggccag aacctcgccc
    18121 gcgccgaact ggagatcgcc ctgcacaccc tcttcgaccg gctgcccacg ctgcgcctgg
    18181 ccgctcccgc agaggaaatc cccttcaaac ccggcgacac gatccagggg atgctggaac
    18241 ttcccgtgac ctggtaagag gcttccgcca tgcatatcga catcgacaag gacgtctgca
    18301 tcggtgcggg ccagtgtgcc ctgaccgccc cggacgtgtt cacccaggac gacgacggct
    18361 acagcgccct gctgccgggc cgggaggacg gcagcggcag cccgctggtg cgggaggcgg
    18421 cccgggcctg ccctgtgagc gccatcaccg tctccgagac cgtgggctga cacagcatca
    18481 ggcgacctcc aggagcaacc gggcggcctc ccgcgcctcg gccgcgggct cggcgctcct
    18541 ggtgacaccc gccgtgacca tggcgccctc ggcgagcagg aagagctgcc cggccagtgg
    18601 gccgggcagc cccgccgctt cgaccagtga ggtgaggtag tcccggaaag cccgcttgtg
    18661 ggcacgcacc tggccggcca cgcgcgggga cgtcgcgccg agctccccgt acgcgttgat
    18721 ccacgcgcag ccccggaagt ccggctcgcc gaaccaccgg cccagccagt cgaacacggc
    18781 aaggatccgc tcccgcggct ccccgtaccg ctcgacgtac tcggccagtt gcccgcgcca
    18841 gcgcgcgtca cgccgctcca gatacgcctc caccagctgc tccttcgccg ggaacagctg
    18901 atagagccgc ttgagcgaga ccccggagct gccgcggacg tcgtccatgc cgacggaccg
    18961 cacgccccgc ccgtagaaca gctcctcggc ggcgtccagc gcccgctccc gggccactgc
    19021 gctgtccatg tacgaccact ccttgacgcg agaacgagcg ttctcctacc gtagcaccgc
    19081 tggggagaac gcccgttctc cactgtcgat caggggagga cccatgaccg gccgcccgcc
    19141 gctgccgccc ttcacgcggg acaccgccgc gcagaaggtc caggccgccg aggacgcctg
    19201 gaacacccgc gatccgcaca aggtcgccct cgcctactcg gaggactccg tctggcgcaa
    19261 ccgcgacacc ttcgtcaccg gccgcgccgg gatcgccgag ttcctgaccc ggaagtggga
    19321 gcgcgagcag gagtacgcgc tgcgcaagga cctgtgggcc ttcgacggca accgcatcgc
    19381 cgtccgcttc cagtacgagt gccgggacgc cgacggccgc tggtggcgct cctacggcaa
    19441 cgaactgtgg gagttcgacg agcacggcct gatgacccgc cgcgaggcga gcatcaacga
    19501 cgtaccgatc gaggagcggg agcgccgcat cttcggccca cggccggagc cggagcgcgg
    19561 agccacgctc cccgtccggt gaggcaggcg gagtgactag ggtttccggg atgaccgaac
    19621 agcccacccg gaagcccttc ctctacgtcg tcgtctgcgc cgccggtatc gccgcggacg
    19681 tcagcaaact gatcaccgcg gcgcaggagc gagactggga ggtcggtgtc atcgccacgc
    19741 ccgtcgccat gaacggcttc ttcgacaccg cggccgtcga ggcacagacg ggccgcccga
    19801 tccggtccgc ctggcgcacg ccgggtgagc cgcgcccgtt cccggcgccc gacgccgtgg
    19861 tcgtcgcgcc cgccaccttc aacaccgtca acaagtgggc ggccggcatc gccgacaccc
    19921 tcgccctggg caccctgtgc gaggccgcgg gactcggtgt gccgatcgcc gtcctgccgt
    19981 gcgtggccga cgcgctgtcc tcccaccccg cctaccggga cagtctggaa cggctgcggg
    20041 ggatgggcgt gcggttcggg gacccgtact ccggagagcc gaaagaggac ggcgggcggc
    20101 cggagttcgg gtgggagcgg gcgctggacc tggtcgaacg cggctgacgg tcagccgctg
    20161 accccgcaca ggctcactgc ggcccgggca cgtcttcgag tgcacgcgaa cacgtacgct
    20221 ccgtctggaa cacctcccga aggcaggagc agcaacgatg cagtacgtga agctcggttc
    20281 gacgggcctg gacgtgtcgc ggatctgtct ggggtgcatg acctacggcc tgccggaccg
    20341 gggccggcac gagtggaccc tcgacgagga ggcctcgcgc ccgctgatcc ggcaggcggt
    20401 cgaggcgggg atcaacttct tcgacacggc gaacgtctac tccgacggca ccagcgagga
    20461 gatcgtcggc cgggccctgc gcgacttcgc ccgccgtgac gagatcgtgc tcgcgacgaa
    20521 ggtgcacggc cggatgcgcc ccgggcccaa cggcggcgga ctgtcccgca aggccatcct
    20581 cagcgagctc gaccagagcc tcacccggct cggcaccgac tacgtcgacc tctaccagat
    20641 ccaccgcttc gacccgcata ccccggtcga ggagacgatg gaggccctgc acgacgtcgt
    20701 caaggccggc aaggtccgtt acatcggggc gagttcgatg tacgcctggc agttctccaa
    20761 ggcccagtac accgcccggc tgaacggttg gacccgcttc gtctccatgc agaaccacta
    20821 caacctcctc taccgcgagg aggagcgcga gatgctgccc ctgtgcgcgg accagggcgt
    20881 cggcgtgctg ccctggagcc ccctcgcccg gggccgcctc acccgcgact ggggcaccac
    20941 gaccgagcgc agcgccaccg acaccttcgg cggcaacctc taccaggagg gcgaccggac
    21001 catcgtcgag gcggtcaccc gcatcgccga gg
//
