LOCUS       NZ_CP023694            21086 bp    DNA     linear   CON 13-JUL-2024
DEFINITION  Streptomyces coeruleorubidus strain ATCC 13740 chromosome, complete
            genome.
ACCESSION   NZ_CP023694
VERSION     NZ_CP023694.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces coeruleorubidus
  ORGANISM  Streptomyces coeruleorubidus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 9335698)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008705135.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:16:00
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 8,499
            CDSs (total)                      :: 8,405
            Genes (coding)                    :: 8,179
            CDSs (with protein)               :: 8,179
            Genes (RNA)                       :: 94
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 73
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 229
            CDSs (without protein)            :: 226
            Pseudo Genes (ambiguous residues) :: 0 of 229
            Pseudo Genes (frameshifted)       :: 96 of 229
            Pseudo Genes (incomplete)         :: 175 of 229
            Pseudo Genes (internal stop)      :: 12 of 229
            Pseudo Genes (multiple problems)  :: 53 of 229
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 14:54:21
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6176739
            Orig. end                         :: 6197825
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023694.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21086
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="19"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21086
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21086
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11086](+)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11086
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(120..1436)
                     /db_xref="GeneID:91420030"
                     /gene="aroA"
                     /locus_tag="CP976_RS28655"
                     /old_locus_tag="CP976_28685"
     CDS             complement(120..1436)
                     /EC_number="2.5.1.19"
                     /GO_function="GO:0003866 - 3-phosphoshikimate
                     1-carboxyvinyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0009423 - chorismate biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420030"
                     /gene="aroA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522882.1"
                     /locus_tag="CP976_RS28655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28685"
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="WP_150482930.1"
                     /transl_table=11
                     /translation="MAPNTADTALWPAPHASGAVDATVHVPGSKSVTNRALVLASLASE
                     PGWLRRPLRSRDTLLMAGALRAMGIEIEEGVGPDGTGEAWRVLPTGLRGPATVDVGNAG
                     TVMRFLPPVAALADGPVRFDGDPRSYERPLNGVIDALRQLGARIDDDGRGALPLTVHGS
                     GALDGGTVAIDASSSSQFVSALLLSGPRFNQGVEVRHTGATLPSMPHIRMTVDMLRAVG
                     AQVDTPESGGEPNVWRVTPGALLGRDLTIEPDLSNAQPFLAAALVTGGRVVVPDWPSRT
                     TQPGDRLREIFTEMGGSCELTEFGLVFTGSGSIHGIDVDLSEVGELTPGIAAVAALADS
                     PSTLRGVAHLRLHETDRLAALTKEINELGGDVTETADGLHVRPRRLHGGIFHTYDDHRM
                     ATAGAIIGLAVEGVQIENVATTAKTLPDFPDLWTGMLGA"
     gene            complement(1546..2268)
                     /db_xref="GeneID:91420031"
                     /locus_tag="CP976_RS28660"
                     /old_locus_tag="CP976_28690"
     CDS             complement(1546..2268)
                     /codon_start=1
                     /db_xref="GeneID:91420031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992842.1"
                     /locus_tag="CP976_RS28660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28690"
                     /product="M50 family metallopeptidase"
                     /protein_id="WP_059416546.1"
                     /transl_table=11
                     /translation="MDSTATASLASLWDEVSGTQPDPDLWVVIATLVAALAVVIPHGLW
                     RVSRNAITIAHEGGHGLVALLTGRTLTGIRLHSDTSGLTVSRGKPYGIGMILTAASGYT
                     APPLLGLGGAALLGSGRITLLLWLATALLLAMLVMIRNAYGALTMIVTGGLFVLVSWLA
                     GPQVQAAFAYVVVWFLLIGGVRPAFELQAKRSRGGAGDSDADQLSRLTHVPAGLWLFLF
                     HAVSLCSLIGGGRWLLEM"
     gene            2372..3187
                     /db_xref="GeneID:91420032"
                     /locus_tag="CP976_RS28665"
                     /old_locus_tag="CP976_28695"
     CDS             2372..3187
                     /GO_function="GO:0003697 - single-stranded DNA binding
                     [Evidence IEA]"
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009432 - SOS response [Evidence IEA]"
                     /GO_process="GO:0018142 - obsolete protein-DNA covalent
                     cross-linking [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019980380.1"
                     /locus_tag="CP976_RS28665"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28695"
                     /product="SOS response-associated peptidase"
                     /protein_id="WP_150482931.1"
                     /transl_table=11
                     /translation="MCGRYAASRRPEDLAGTFEIEKWEPEETLEPDYNVAPTKEVYAVL
                     DRPLKDADDPRPVRQLRTLKWGLVPSWSKTPEGGARMINARAETVHEKPSYRRAFTSRR
                     CILPADGYYEWVTGTQERELEVEGKKKRPRKQPYFVTPADGSVFAMAGLYEFWRDKTLP
                     DDHPQAWWVTCSVITTEAEASPLAVSPADGPRALAEIHPRMPLMLTPDRWDAWLDPSRT
                     DADELRELLAPPPAGLMRAYPVTTAVSNVRNNGPELLKELEGPEEGTLF"
     gene            3207..3854
                     /db_xref="GeneID:91420033"
                     /locus_tag="CP976_RS28670"
                     /old_locus_tag="CP976_28700"
     CDS             3207..3854
                     /codon_start=1
                     /db_xref="GeneID:91420033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019522885.1"
                     /locus_tag="CP976_RS28670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28700"
                     /product="alpha/beta family hydrolase"
                     /protein_id="WP_229875575.1"
                     /transl_table=11
                     /translation="MTNAANVTTETVETDAGPARITWHTAGKPRLVLAVSHGAGGGIEA
                     RDLKALAAALPAHGVTVARVEQPWRVAGKKLAPAPKTLDLGWRGIWPALAEPGLPVVSG
                     GRSAGARVACRTATELGARAVLALSFPLHPPGRPEKSRAAELLGSGVPTLVVQGGNDPF
                     GNPGEFPEGPYELVEVPHGDHGFAVPKRAEITQEEAVAVITDAVVEWTGSLG"
     misc_feature    complement(4041..4055)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.77"
                     /tool="antismash"
     gene            4111..4797
                     /db_xref="GeneID:91420034"
                     /gene="sigR"
                     /locus_tag="CP976_RS28675"
                     /old_locus_tag="CP976_28705"
     CDS             4111..4797
                     /codon_start=1
                     /db_xref="GeneID:91420034"
                     /gene="sigR"
                     /gene_functions="regulatory (smcogs) SMCOG1032: RNA
                     polymerase, sigma-24 subunit, ECF subfamily"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003973756.1"
                     /locus_tag="CP976_RS28675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28705"
                     /product="RNA polymerase sigma factor SigR"
                     /protein_id="WP_086846661.1"
                     /transl_table=11
                     /translation="MGPVTGTDAGTEHGQAEQPEGQGGTGAETAAERNARFERDALEFL
                     DQMYSAALRMTRNPADAEDLVQETYAKAYASFHQFREGTNLKAWLYRILTNTFINSYRK
                     KQREPQRSAAEEIEDWQLARAESHMSTGLRSAESQALDHLPDSDVKQALQAIPEEFRIA
                     VYLADVEGFAYKEIADIMGTPIGTVMSRLHRGRRQLRGMLEDYARDRGMVPAGAGESNE
                     AKGSGS"
     misc_feature    4133..4148
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 22.19"
                     /tool="antismash"
     gene            4794..5105
                     /db_xref="GeneID:91420035"
                     /gene="rsrA"
                     /locus_tag="CP976_RS28680"
                     /old_locus_tag="CP976_28710"
     CDS             4794..5105
                     /GO_function="GO:0016989 - sigma factor antagonist activity
                     [Evidence IEA]"
                     /GO_process="GO:0045454 - cell redox homeostasis [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420035"
                     /gene="rsrA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326971.1"
                     /locus_tag="CP976_RS28680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28710"
                     /product="mycothiol system anti-sigma-R factor"
                     /protein_id="WP_033314427.1"
                     /transl_table=11
                     /translation="MSCGEPHETDCSEILDHLYEFLDREMPDSDCVKFEHHFEECSPCL
                     EKYGLEQAVKKLVKRCCGHDDVPGDLRDKVMGRIELIRSGQAVPEQDVTASPATPQES"
     gene            5259..6590
                     /db_xref="GeneID:91420036"
                     /locus_tag="CP976_RS28685"
                     /old_locus_tag="CP976_28715"
     CDS             5259..6590
                     /EC_number="3.1.4.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047597.1"
                     /locus_tag="CP976_RS28685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28715"
                     /product="HD-GYP domain-containing protein"
                     /protein_id="WP_150482933.1"
                     /transl_table=11
                     /translation="MEAVPVRARVYVACVLAAALLCLLPLPGVRTPWWAVALLAALYAG
                     CERVARSRFVGISHPAGTFYPVLLAGAFLLPAPAAALVAVPGALLSHVEQRPVALRRVW
                     RAAQLVLGVWAAARVHRALGGRDAVAAGDVPYALGPAGAAVLAFCLVLAVLDGGILAVA
                     ERVPVRRAWRGLVSRSLAPIAVHGLAGLMMAVLWRSPYGPVAALLVLLPMCVSWWAFAQ
                     YHRERAAHQATIRALVQAVDIKDGYTRGHSERVGQASMMIARELGMDDERVEVLRFAGI
                     LHDVGKLGVPTRLLRKDGPLTPEERRVIELHPEYGHEMVRGIGFLGEARAAVLHHHERL
                     DGTGYPYGLMGSQIPESARVVAVADAFDAMTSTRSYSRARPVAVALAELKRCSGSQFDP
                     VMVAALVEAVGRAGWRPAVTADVVDPPRIPPPGAPVSSPPGAHR"
     gene            6587..7834
                     /db_xref="GeneID:91420037"
                     /locus_tag="CP976_RS28690"
                     /old_locus_tag="CP976_28720"
     CDS             6587..7834
                     /codon_start=1
                     /db_xref="GeneID:91420037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047595.1"
                     /locus_tag="CP976_RS28690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28720"
                     /product="HD domain-containing protein"
                     /protein_id="WP_190146894.1"
                     /transl_table=11
                     /translation="MSAHRPPPLFTLVHGCAALLAAGSLAVTLYNGLEERRVALAFGVL
                     VTVGELARRNGAQVREPAPLGAAAALSYALLGEAGGRATHHGLAQVVAVVLAASLLGSV
                     PHVARGQGPTLDHLARRVLTAGFVAVCFQPPYNRGMFDDWGGPAYALLLLALLSLTALC
                     DAVLAAALAHSRTGWPFGPVLRDELRAVFGIGSAVIATGAVMALAVAVVGLWALPVFSV
                     PLLLAQMSFRRYAAVRATYRQTIASLARATEVAGYTPCGHARRVAALSQAVGRDLGLTE
                     PELAVLEYAALMHDIGQLSLVDPVPSGATADLPAAEQRRIALLGGAVVRQTGVDEAVAV
                     VVERQADPYAEQPLAARIVRAVNAYEEKSREGGLGGPLTALEELRLATAGEYAPEVVES
                     LARVLARSSLTLPVTG"
     gene            7952..8932
                     /db_xref="GeneID:91420038"
                     /locus_tag="CP976_RS28695"
                     /old_locus_tag="CP976_28725"
     CDS             7952..8932
                     /codon_start=1
                     /db_xref="GeneID:91420038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019889310.1"
                     /locus_tag="CP976_RS28695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28725"
                     /product="hypothetical protein"
                     /protein_id="WP_150485542.1"
                     /transl_table=11
                     /translation="MRIFGKGRHRPSASWRQATDRAFTLIGDGRYEDAGALLTRAADLE
                     PWLSESWFNLALLHKFRHDWEQARAAGLRAVALLDRDTGAPDWWNVGIAATALQDWPLA
                     RRAWQAYGLRVPGPPNDSGEPVGMDLGSAAVRLSPEGEAEVVWGRRLDPARIEVLSIPL
                     PSSGRRWGEVVLHDGVPHGERTTAAGHTYPVFDEIELWAPSPVPTWVVLLEAATESDRD
                     ALEQLAADAGFAAEDWSSSVRLLCRMCSESRMPSDEGDGEHLDPHDHSEPGHPGPLGHR
                     TDGQLWVPERECGLAAPASLVRGLLDGWVADSPDSRDWRDLEEVC"
     gene            9060..9710
                     /db_xref="GeneID:91420039"
                     /gene="def"
                     /locus_tag="CP976_RS28700"
                     /old_locus_tag="CP976_28730"
     CDS             9060..9710
                     /EC_number="3.5.1.88"
                     /GO_function="GO:0042586 - peptide deformylase activity
                     [Evidence IEA]"
                     /GO_process="GO:0036211 - protein modification process
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420039"
                     /gene="def"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1275: peptide deformylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004983603.1"
                     /locus_tag="CP976_RS28700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28730"
                     /product="peptide deformylase"
                     /protein_id="WP_086849715.1"
                     /transl_table=11
                     /translation="MAQQDTDQQRAGVLPVDDEGYVIDTEDCEEREAAWRERGTSRPIT
                     VVGNPVLHKECKDVTDFGDELQQLVADMFASQRTAEGVGLAANQIGVDLKVFVYDCPDD
                     EGARHTGVVCNPKLVELPAEKRRLDDSNEGCLSVPTAYAPLARPDYAEVTGQDEQGNPI
                     RVRGTGYFARCLQHETDHLYGYLYIDRLSKRERKDALRQMAENEPRYPVVAND"
     gene            10001..11086
                     /db_xref="GeneID:91420040"
                     /gene="cyc1"
                     /locus_tag="CP976_RS28705"
                     /old_locus_tag="CP976_28735"
     CDS             10001..11086
                     /EC_number="4.2.3.37"
                     /GO_function="GO:0052680 - epi-isozizaene synthase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420040"
                     /gene="cyc1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003992851.1"
                     /locus_tag="CP976_RS28705"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28735"
                     /product="epi-isozizaene synthase"
                     /protein_id="WP_150482935.1"
                     /sec_met_domain="T1TS (E-value: 1.1e-62, bitscore: 211.8,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHALSHGTTSTPTTIAVPPSLSLPVIEAAFPRQLHPYWPKCQEKT
                     RVWLLEKRLMPADKVEEYADGLCYTDLMAGYYIGASDEVMQAIADYSAWFFVWDDRHDR
                     DIVHGRPLAWRRLRDRLHSALDTPREHLHHEDPLVAGFADSVLRLYAFLPATWNLRFAR
                     HFHEVIDAYDREFHNRTHGIVPTVEEYLRLRRLTFAHWIWTDLLEPTAGCELPDAVRKH
                     PAYRRAALLSQEFAAWYNDLCSLPKEIAGDEVHNLGISLITHERLTLEQAVAEVRSRVE
                     NCIMEFLDVEQTALRFADGLADGTVRGKELSAAVRACLSNMRNWFSSVYWFHHESGRYM
                     VDSWDDRSTPPYVNNEAAGEK"
     misc_feature    10883..10885
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            11083..12453
                     /db_xref="GeneID:91420041"
                     /locus_tag="CP976_RS28710"
                     /old_locus_tag="CP976_28740"
     CDS             11083..12453
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420041"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1034: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326965.1"
                     /locus_tag="CP976_RS28710"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28740"
                     /product="cytochrome P450"
                     /protein_id="WP_150482936.1"
                     /sec_met_domain="p450 (E-value: 4.7e-69, bitscore: 232.2,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVESVKPEAPLVPELREPPRASGGVPVLGHGWKLVRDPLAFMSR
                     LRDHGDVVRLKLGPKTVYAVTTPALTGALALSNDFIIAGPLWESLEGLLGKEGVATANG
                     PRHRRQRRTIQPAFRLDAIPAYGPIMEEEAHALTERWKPGQTIDCTSESFRVAVRIAAR
                     CLLRGDYMDERAERLCVALATVFRGMYRRMVVPLGPLYKLPLPANREFNRALADLHLLV
                     DEIVAERRASGQKPDDLLTALLEATDENGDPIGEQEIHDQVVAILTPGSETVASTIMWL
                     LHMLAEHPEHADRVRDEVEAVTGGKPVAFADVRGLRHTNNVVVESMRLSPAVWILTRRA
                     VRDTELGGYRIPAGADIVYSPYAIQRDPKSYARNLDFDPDRWLPDRVKDVPKHAMSPFS
                     VGNRKCPSDHFSMAQLTLITAALATRYRFEQVAGSNDSTRVGITLRPHDLRVRPVVR"
     gene            complement(12466..13428)
                     /db_xref="GeneID:91420042"
                     /locus_tag="CP976_RS28715"
                     /old_locus_tag="CP976_28745"
     CDS             complement(12466..13428)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420042"
                     /gene_functions="regulatory (smcogs) SMCOG1287: AraC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020700022.1"
                     /locus_tag="CP976_RS28715"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28745"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_150482937.1"
                     /transl_table=11
                     /translation="MLQNVAVALLDGVNPFELGVVCEVFGTDRSDEGLPVYDFAVASAE
                     GPVLRMNSGFSLQAEHGLERLETADLIAVPAGHSYAYRDFPPELLAALRRGVDRGARVL
                     SVCSGVFVLAAAGLLDGRRCATHWKHAKDLARQYPRVIVEPDVLYVDEDPVITSAGTAA
                     GIDACLHLVRKEQGSEVANKIARRMVVPPHRDGGQAQYIERPLPHPEGDTIVDVLAWME
                     RHLDEEVTVEQLAAHAHMSPRTFARRFQQETGTTPYRWILRQRVLLAQRLLEATDETMD
                     AIAGRTGFGNAATLRHHFVRAIGTTPNAYRRTFRGPEAA"
     gene            13522..13764
                     /db_xref="GeneID:91420043"
                     /locus_tag="CP976_RS28720"
                     /old_locus_tag="CP976_28750"
     CDS             13522..13764
                     /codon_start=1
                     /db_xref="GeneID:91420043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010047586.1"
                     /locus_tag="CP976_RS28720"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28750"
                     /product="hypothetical protein"
                     /protein_id="WP_086849729.1"
                     /transl_table=11
                     /translation="MDTNQTQTLIAMIFVLGTLVLLVLPSVIGIVRDRRVDRQIREAQE
                     IREGVAAQKSSSRSTVPSTATWYAEGRRSKKLVNS"
     misc_feature    complement(13567..13586)
                     /note="TFBS match to DosR, Hypoxia stress response
                     regulator, confidence: weak, score: 23.61"
                     /tool="antismash"
     gene            complement(13677..14699)
                     /db_xref="GeneID:91420044"
                     /locus_tag="CP976_RS28725"
                     /old_locus_tag="CP976_28755"
     CDS             complement(13677..14699)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0009263 - deoxyribonucleotide biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326963.1"
                     /locus_tag="CP976_RS28725"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28755"
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="WP_150482938.1"
                     /transl_table=11
                     /translation="MTQNLLDPGFELTLRPMRYPDFYERYRDAIKNTWTVEEVDLHSDV
                     ADLAKLSPDEQHLIGRLVAFFATGDSIVANNLVLTLYKHINSPEARLYLSRQLFEEAVH
                     VQFYLTLLDTYLPDHDDRAAAFAAVENIPSIREKAEFCFKWMAAFDGTEEVDQLDRLET
                     QADRRRFLLNLICFAACIEGLFFYGAFAYVYWFRSRGLLHGLATGTNWVFRDETMHMSF
                     AFDVVDTVRKEEPELFDDQLQQQVTDMLREAVEAELQFARDLCGDGLPGMNTESMRQYL
                     ECVADQRLTRLGFAPVYGSENPFSFMELQGVQELTNFFERRPSAYQVAVEGTVDLDEDF
                     "
     gene            complement(14756..17113)
                     /db_xref="GeneID:91420045"
                     /locus_tag="CP976_RS28730"
                     /old_locus_tag="CP976_28760"
     CDS             complement(14756..17113)
                     /EC_number="1.17.4.1"
                     /GO_component="GO:0005971 - ribonucleoside-diphosphate
                     reductase complex [Evidence IEA]"
                     /GO_function="GO:0004748 - ribonucleoside-diphosphate
                     reductase activity, thioredoxin disulfide as acceptor
                     [Evidence IEA]"
                     /GO_process="GO:0009265 - 2'-deoxyribonucleotide
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674902.1"
                     /locus_tag="CP976_RS28730"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28760"
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="WP_150482939.1"
                     /transl_table=11
                     /translation="MTIAPADPVSAAEEEHDGPGAALLRTLTELTADLPDADPGRIAAA
                     ALRGRSARADEPELRELATEAAAGLISEDPAYSRLAARLLTIGIRAEAASQGVTCFTES
                     VAVGHREGLIADRTAEFVRVHAARLDALIDTAADDRFGYFGLRTLHSRYLLRHPITRKV
                     IETPQHFMLRVAAGLAEDDTRRSVDEVAALYGLMSRLDYLPSSPTLFNSGTRHPQMSSC
                     YLLDSPKDELDSIYDRYHQVARLSKHAGGIGIAYSRIRARGSLIRGTNGHSNGIVPFLK
                     TLDASVAAVNQGGRRKGAAAVYLETWHSDIEEFLELRDNTGEDARRTHNLNLAHWVPDE
                     FMRRVNADAQWSLFSPADVPELVDLWGEEFDAAYRAAEAKGLAKKTLPARELYGRMMRT
                     LAQTGNGWMTFKDAANRTANQTAEPGHVVHSSNLCTEILEVTSDGETAVCNLGSVNLGA
                     LVDQAGGDIDWERLDETVRTAVTFLDRVVDINFYPTEQAGRSNARWRPVGLGVMGLQDV
                     FFKLRLPFDSPEAKALSTRIAERIMLAAYEASADLAERNGPLPAWEKTRTAKGVLHPDH
                     YDVELTWPERWAALRERVAATGMRNSLLLAIAPTATIASIAGVYECIEPQVSNLFKRET
                     LSGEFLQVNSYLVQELKRLGVWDARSREALREANGSVQDFAWIPEDVRALYRTAWEIPQ
                     RGLIDMAAARTPFLDQSQSLNLFLETPTIGKLSSMYAYAWKSGLKTTYYLRSRPATRIA
                     RAAQAAVPAQATPDPEAVACSLENPESCEACQ"
     regulatory      complement(17234..17380)
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    complement(17360..17374)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 24.21"
                     /tool="antismash"
     misc_feature    complement(17391..17405)
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 23.7"
                     /tool="antismash"
     gene            17646..18239
                     /db_xref="GeneID:91422890"
                     /locus_tag="CP976_RS43870"
     CDS             17646..18239
                     /codon_start=1
                     /db_xref="GeneID:91422890"
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP976_RS43870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_229875576.1"
                     /transl_table=11
                     /translation="MRLVVQVKLLPTPEQASALEATLRACNRAATYASQVAFAENLKDR
                     NGLQKEVYADLKATFGLSAQPAVRAVKKVVDAYATLKANLQAGNLGSPTSKRHRRAVGS
                     PIAFRPEAAQPFDDRCLSWQYDARTVSVWTVAGRMKGIRFVCSPEQLKTLVQYRKGESD
                     LVQRGRKWFLIATCDIPGPGCTSLPIGSGSTGAS"
     gene            18236..18679
                     /db_xref="GeneID:91422891"
                     /locus_tag="CP976_RS43875"
     CDS             18236..18679
                     /GO_function="GO:0004803 - transposase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91422891"
                     /inference="COORDINATES: protein motif:HMM:NF013544.4"
                     /locus_tag="CP976_RS43875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="WP_229875577.1"
                     /transl_table=11
                     /translation="MNLATTSDGTNHQGRRLSRYRRWQARKRAEFQARRPRSATRRLAR
                     RAQKERRHATHVSSWPFHQLGHHLAYKARKAGVPFLEVDARHTSQRCPRCGHTERANRP
                     TRDHFRCRRCGLAGPADVVAGVNVRDRARSAWAFVTMPVPHPV"
     gene            complement(18775..19296)
                     /db_xref="GeneID:91420046"
                     /locus_tag="CP976_RS28740"
                     /old_locus_tag="CP976_28770"
     CDS             complement(18775..19296)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /db_xref="GeneID:91420046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019326961.1"
                     /locus_tag="CP976_RS28740"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28770"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_150482940.1"
                     /transl_table=11
                     /translation="MDILIRRVKPAEHDALGEITAQAYLEDGLLDFGESDWYLGELKDV
                     ARRAAAADVLVATRGEHLLGGVTFVPSGGPMADIALPGEAEIRMLAVAHEARGQGAGEA
                     LVRACVDRARATDGCVRVVLSTQRTMHAAHRIYERLGFVRAPERDWNPIPELDDITLLT
                     YELTLSPSRP"
     gene            complement(19369..20997)
                     /db_xref="GeneID:91420047"
                     /locus_tag="CP976_RS28745"
                     /old_locus_tag="CP976_28775"
     CDS             complement(19369..20997)
                     /codon_start=1
                     /db_xref="GeneID:91420047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014674905.1"
                     /locus_tag="CP976_RS28745"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP976_28775"
                     /product="monocarboxylate uptake permease MctP"
                     /protein_id="WP_150482941.1"
                     /transl_table=11
                     /translation="MKDGVNGVALAVFIFFFLLVTVMGFLAARWRKAENEHSLDEWGLG
                     GRSFGTWVTWFLLGGDLYTAYTFVAVPAAIYAAGAAGFFAVPYTILVYPLIFTFLPRLW
                     SVSHKHGYVTTSDFVRGRFGSKGLSLAVALTGILATMPYIALQLVGIQAVLDVMGVGGG
                     EDTNWFIKDLPLLIAFGVLAAYTYSSGLRAPALIAFVKDTLIYIVIAVAIIYIPIKLGG
                     FDEIFARAGEAYGQTNPATGAPRGALVPPEAGQWTYATLALGSALALFMYPHSITATLS
                     SRSREVIRRNTTILPLYSLMLGLLALLGFMAIAAGIKVQNGQLAIPQLFETMFPDWFAG
                     VAFAAIGIGALVPAAIMSIAAANLFTRNIYKDFIKPDATPAQETKVSKLVSLLVKVGAL
                     AFVLTMDKTVAINFQLLGGIWILQTFPALVGGLFTRWFHRWALLAGWAVGMVYGTVAAY
                     GVASPTQKHFGGSSKEIPGIGEIGYIGLTAFVLNVVVTVVLTFVLRALKAPDGIDETKP
                     EDYTADAGDPGVQVELPPATAGTSH"
     misc_feature    21045..21059
                     /note="TFBS match to NrdR, Represses ribonucleotide
                     reductase encoding genes, confidence: medium, score: 21.83"
                     /tool="antismash"
ORIGIN
        1 gtcctcgtgc ttgggccgga tgttcgtccg gggccgtgtg ttccggcggc cgggacgggt
       61 gcggatgtcg tcctcgtcgg tgtgcttgcc gtagcggcgc atgacctggt ccccgtgtcc
      121 tacgccccga gcatcccggt ccacaggtcg gggaagtcgg gcagggtctt tgccgtcgtc
      181 gccacgttct cgatctgcac gccctccacc gcgaggccga tgatcgcccc ggccgtggcc
      241 atgcggtggt cgtcgtacgt gtggaagatc ccgccgtgca ggcggcgcgg gcggacgtgc
      301 agaccgtcgg cggtctccgt gacgtcaccg ccgagttcgt tgatctcctt ggtcagcgcg
      361 gccaggcggt ccgtctcgtg cagccgcaga tgggccacgc cgcgcagggt cgacggggag
      421 tcggcgaggg ccgcgaccgc cgcgatgccc ggcgtcagct caccgacctc gctcaggtcg
      481 acgtcgatgc cgtggatcga gccggagccg gtgaacacga gcccgaactc ggtcagttcg
      541 caggagccgc ccatctcggt gaagatctcg cgcagccggt caccgggctg ggtggtgcgg
      601 gacggccagt ccgggacgac gacccggccg ccggtcacca gcgcggccgc caggaacggc
      661 tgggcgttgg acagatcggg ctcgatcgtc agatcgcggc cgagcagagc gccgggcgtg
      721 acccgccaga cgttgggctc gccgcccgac tcgggcgtgt ccacctgggc gccgaccgcg
      781 cgcagcatgt cgacggtcat ccggatgtgc ggcatggagg gcagcgtggc gccggtgtgg
      841 cggacctcga cgccctggtt gaagcgcggg ccggacagca gcagggcgct cacgaactgc
      901 gacgaggagg acgcgtcgat ggcgaccgtg ccgccgtcca gggcgccgct gccgtgcacg
      961 gtcaacggca gcgcgccccg gccgtcgtcg tcgatccggg caccgagctg gcgcagcgcg
     1021 tcgatgactc cgttcagggg acgctcgtag gagcgggggt caccgtcgaa gcggacggga
     1081 ccgtccgcga gcgcggcgac cggcggcagg aaccgcatca ccgtgccggc gttgccgacg
     1141 tcgaccgtgg ccgggccgcg caggcccgtg gggagcacac gccaggcctc gccggtgccg
     1201 tccgggccca cgccctcctc gatctcgatg cccatggcgc gcagcgcgcc ggccatcagc
     1261 agggtgtcgc gggagcgcag ggggcggcgc agccagcccg gttcggaggc gagggaggcg
     1321 aggacaaggg cgcggttcgt gaccgacttg gacccgggca cgtggaccgt cgcgtcgacg
     1381 gctccgctcg cgtgcggggc gggccaaagg gcggtgtctg cggtgttcgg ggccatggct
     1441 tcactttata aggaggcggt ggctcgggtg cggcgccgtg ggggccggtc gcgcccacgc
     1501 ggcggagccg cacatcggcg cagactcgcg cccccgcggg gcgcgtcaca tctccaggag
     1561 ccacctgccc ccaccgatca gcgagcacag cgacaccgcg tggaacagga acagccacaa
     1621 ccccgccggc acgtgcgtca gccgcgacag ctggtccgcg tccgagtcgc ccgccccgcc
     1681 ccgcgaccgc ttggcctgga gctcgaacgc cggacgcacc ccgccgatca gcaggaacca
     1741 caccaccacg tacgcgaacg ccgcctggac ctgcgggccg gccagccagg acaccaggac
     1801 gaacaggccg ccggtgacga tcatggtgag ggcgccgtag gcgttgcgga tcatcacgag
     1861 catggccagc agcagggccg tggccagcca cagcaggagc gtgatgcggc cggagcccag
     1921 cagggccgca ccgccgaggc ccagcagggg cggggcggtg tagccggagg ccgcggtgag
     1981 gatcatgccg atgccgtacg gcttgccgcg gctgacggtc aggccgctgg tgtccgagtg
     2041 cagccgtatg ccggtgaggg tgcggccggt gagcagggcc acgagcccgt ggccgccctc
     2101 gtgggcgatg gtgatggcgt tgcgggagac gcgccacagg ccgtgcggga tcaccacggc
     2161 gagcgcggcc accagagtcg cgatcacgac ccacaggtcg gggtcgggct gggtgccgga
     2221 gacctcgtcc cagagggagg cgagggaggc ggttgcggtg ctgtccatgt gcggcgatgg
     2281 ctccctgtgg gcggattcag agggggcggc gcgaagcgcc tcgttgaggg gtggtggtcg
     2341 ggagacgggt gggcctggca gtgtggcacg tatgtgcgga cggtatgcag cgagtcgtag
     2401 gccagaggat ctcgcaggaa cctttgagat cgagaagtgg gagcccgagg agactctgga
     2461 gcccgactac aacgtggcgc ccaccaaaga ggtctacgcc gtcctcgacc gccctctgaa
     2521 agacgcggac gacccgcgac cggttcggca gctgcgcacg ctgaagtggg ggctcgtccc
     2581 gtcctggtcg aagacccccg agggcggcgc ccggatgatc aacgcccgcg cggagaccgt
     2641 ccacgagaag ccgtcctacc gccgcgcctt cacctcccgg cgctgcatcc tgcccgccga
     2701 cggctactac gagtgggtca ccggcacgca ggagcgcgag ctggaggtcg aggggaagaa
     2761 gaagcggccc cgcaagcagc cctacttcgt gaccccggcg gacgggtcgg tcttcgcgat
     2821 ggccgggctg tacgagttct ggcgggacaa gacgctgccg gacgaccacc cgcaggcctg
     2881 gtgggtgacg tgctccgtca tcaccaccga ggccgaggcg agcccgctgg cggtctcccc
     2941 ggcggacggt ccgcgggccc tggccgagat ccacccccgg atgccgctga tgctgacgcc
     3001 ggaccgctgg gacgcctggc tggacccgtc ccgcacggac gccgacgagc tgcgcgagct
     3061 gctcgccccg ccgcccgccg ggctgatgcg cgcctatccc gtcacgacgg ccgtcagcaa
     3121 cgtccgcaac aacggcccgg agctgctgaa ggagctggaa gggccggaag agggcacact
     3181 cttctgacgt gacggatgtg aacgatgtga ccaatgcggc aaacgtgacg acggagaccg
     3241 tcgagaccga cgccggcccc gccagaatca cctggcacac ggcgggaaag ccccggctgg
     3301 tcctcgccgt cagccacggc gccggcggcg gcatcgaggc ccgcgacctg aaggccctgg
     3361 ccgccgccct gcccgcccac ggcgtcaccg tggcccgtgt ggagcagccc tggcgagtgg
     3421 ccgggaagaa gctcgcgccc gcgccgaaga ccctggacct cgggtggcgg ggcatctggc
     3481 ccgccctcgc cgagcccggc ctgccggtcg tgtccggcgg acgcagtgcc ggggcacgcg
     3541 tggcctgccg taccgccacc gagctcggcg cccgcgcggt cctcgccctc agcttccccc
     3601 tccacccgcc cggcaggccc gagaagtccc gcgccgccga actgctgggt tccggggttc
     3661 ccaccctggt cgtccagggc gggaacgacc cgttcgggaa tcccggggag tttcccgagg
     3721 ggccctacga gctcgtcgag gtgccgcacg gcgatcacgg tttcgccgtc cccaagcgcg
     3781 cggagatcac gcaggaggag gcagtggcgg tcatcacgga cgcggtcgtg gagtggaccg
     3841 ggtcactcgg gtaaagctcc gggaatgccg gggcggcgag cactgttgtg cgggacgtac
     3901 gtgctggaga ccagcaccga cgccgtagga gaggaagtcc gccgcatggg ttcgaccatc
     3961 tgcccgagcc gcagcagccg tgccgacctg gactggacgg tgctgcacgc ggccaggacc
     4021 gcccctattc gggcggcggg cggaccggat cgtcgtctat cctccgattc gggtgagacc
     4081 ggtctcggtc tcacgagaac actggaggag gtgggtccgg tcactgggac cgacgcaggg
     4141 accgaacacg gccaggcgga gcagcccgag ggccagggtg gcacgggcgc ggagacggcc
     4201 gcggagcgca acgcgcgctt cgagcgggac gcgctcgagt tcctcgacca gatgtactcg
     4261 gccgcgctgc gcatgacgcg caacccggcc gacgcggagg acctggtgca ggagacgtat
     4321 gccaaggcgt acgcgtcctt ccaccagttc cgtgagggca ccaacctcaa ggcgtggctg
     4381 taccggatcc tcaccaacac cttcatcaac tcgtaccgca agaagcagcg cgaaccgcag
     4441 cgctcggcgg ccgaggagat cgaggactgg cagctcgccc gcgccgagtc gcacatgtcg
     4501 acgggcttgc gctccgcgga gtcgcaggcg ctcgaccacc tgcccgactc ggacgtgaag
     4561 caagcgctcc aggcgatccc cgaggagttc cgcatcgccg tgtatctcgc ggacgtcgag
     4621 ggctttgcgt acaaggagat cgccgacatc atggggacac ccatcggtac ggtgatgtcc
     4681 cggctgcacc ggggacgccg tcagctgcgc ggcatgctgg aggactacgc ccgtgaccgc
     4741 gggatggtcc cggccggcgc cggagagtcg aacgaagcga aaggctcggg gtcatgagct
     4801 gcggagagcc gcacgagacg gattgcagcg agatcctcga tcatctctac gagttcctcg
     4861 accgtgagat gccggactcg gactgcgtga agttcgagca ccacttcgag gaatgctcgc
     4921 cctgtctgga gaagtacggg ctcgagcagg ccgtgaagaa gctggtcaag cgctgctgcg
     4981 ggcatgacga cgtgccgggc gacctgcgtg acaaggtcat ggggcggatc gagctgatcc
     5041 gctccggcca ggccgtcccc gagcaggacg tcacggcttc gcctgccacg ccgcaggaat
     5101 cctgacactc ctgcgctttt caactacccc gcctctgaag gggtagtcat cctcgaacgc
     5161 atcactcgaa cgtgctaatc cgcgggttat cggcccgcgg agtcccccgt ccgcgtccta
     5221 ggctccgggc ctgacggaga cggccggggg aggggcgtat ggaagcggta ccggtgcggg
     5281 cgcgtgtgta cgtcgcctgt gtcctggccg ccgccctcct ctgtctgctg ccgctgccgg
     5341 gcgtccgtac gccctggtgg gccgtggcct tgctcgccgc gctgtacgcg ggctgcgagc
     5401 gcgtcgcccg gtcccggttc gtcgggatct cccatccggc cgggaccttc taccccgtgc
     5461 tgctcgccgg tgccttcctg ctgcccgcgc ccgccgccgc cctggtggcc gtgcccggtg
     5521 cactgctctc gcatgtcgag cagcggcccg tggcgctgcg ccgggtctgg cgggccgccc
     5581 agctcgtcct cggggtgtgg gccgccgccc gggtgcaccg ggcgctcggc ggacgggacg
     5641 cggtcgccgc cggtgacgtg ccctacgcgc tcggcccggc cggggcggcc gtgctggcgt
     5701 tctgcctggt gctcgcggtg ctggacggcg ggatcctggc cgtcgccgag cgcgtgccgg
     5761 tgcggcgggc ctggcggggg ctcgtgtcgc gctccctcgc gcccatcgcc gtgcacgggc
     5821 tggccgggct gatgatggcc gtgctgtggc gcagccccta cggccccgtg gccgcgttgc
     5881 tcgtgctgct gccgatgtgc gtctcctggt gggccttcgc gcagtaccac cgggaacggg
     5941 ccgcccacca ggcgaccatc cgggcgctcg tccaggccgt cgacatcaag gacggctaca
     6001 cgcggggcca cagcgagcgg gtcgggcagg cctccatgat gatcgcgcgc gagctgggca
     6061 tggacgacga gcgcgtcgag gtgctccggt tcgccgggat cctgcacgac gtcggcaagc
     6121 tcggcgtccc cacccggctg ctcaggaagg acgggccgct gacgcccgag gagcggcggg
     6181 tgatcgagct gcaccccgag tacgggcacg agatggtgcg cggcatcggc ttcctcgggg
     6241 aggcccgcgc cgccgtgctg caccaccacg aacggctgga cggcaccggg tacccgtacg
     6301 gcctgatggg cagtcagata ccggaatcgg cccgggtcgt ggcggtcgcg gacgccttcg
     6361 acgccatgac ctccacgcgg agctacagca gggcccggcc cgtcgcggtc gccctggcgg
     6421 agctgaagcg gtgctccggc agccagttcg acccggtgat ggtcgcggct ctcgtggagg
     6481 ccgtcggccg ggccgggtgg cgccccgccg tgaccgccga cgtcgtcgac ccgccccgga
     6541 tccccccgcc cggcgcaccc gtctccagcc cgccgggagc acaccggtga gcgcgcaccg
     6601 cccgccgccg ctcttcaccc tcgtccacgg ctgtgccgcc ctcctcgcgg ccggctccct
     6661 cgccgtcacc ctctacaacg ggctggagga acgccgggtt gccctcgcct tcggcgtcct
     6721 cgtgaccgtc ggggaactcg cccggcgcaa cggggcgcag gtcagggagc cggcgccgct
     6781 cggggccgcc gcggccctgt cgtacgcgct gctcggcgag gccggcgggc gggccacgca
     6841 ccacggcctc gcccaggtcg tcgccgtcgt gctggccgcc tcgctgctcg gcagcgtgcc
     6901 gcacgtggcg cgcgggcagg gacccacgct cgaccatctg gcacgccggg tgctcaccgc
     6961 cgggttcgtc gccgtgtgct tccagccccc ctacaaccgg ggcatgttcg acgactgggg
     7021 cggccccgcc tacgcgctgc tgctgctcgc gctgctgtcc ctgaccgcgc tgtgcgacgc
     7081 ggtgctcgcc gcagcgctgg cacactcccg caccggctgg cccttcgggc cggtgctgcg
     7141 ggacgagctg cgggccgtgt tcggcatcgg ctccgccgtc atcgcgaccg gtgcggtgat
     7201 ggccctggcg gtcgccgtcg tggggctgtg ggcgctgccc gtgttctccg tgccgctgct
     7261 gctcgcccag atgtcgttcc gccgctacgc cgccgtccgg gcgacctacc ggcagaccat
     7321 cgcctccctg gcacgggcca ccgaggtcgc cgggtacacc ccctgcggac acgcccgccg
     7381 cgtcgccgcg ctcagccagg cggtggggcg tgacctgggc ctcaccgagc ccgagctggc
     7441 cgtcctggag tacgccgcgc tcatgcacga catcggccag ctgagcctcg tcgacccggt
     7501 gccgtcgggc gccaccgccg acctgcccgc cgcggaacag cggcggatcg cgctgctcgg
     7561 cggggccgtc gtacggcaga cgggtgtcga cgaggcggtc gccgtggtcg tggagcggca
     7621 ggccgacccc tacgcggagc agccgctcgc cgcgcggatc gtccgggccg tgaacgcgta
     7681 cgaggagaag tcccgggaag gtggcctggg cggaccgctg acggcgctgg aggaactccg
     7741 gctcgccacc gccggggagt acgccccgga ggtggtggaa tcgctggccc gggtactggc
     7801 aagaagcagt ctgaccttgc ccgtgactgg gtaacccatg ggtaatgagc gccccggagg
     7861 ccgtacgtgg ttggatgcga agaagaaggt gtccgggggc tcgaaacaca gctacggcca
     7921 gcccaccgca cggaactggc aggcgggaat cgtgaggatc ttcggcaagg gacggcaccg
     7981 gccctccgcc tcctggcggc aggccacaga ccgggcgttc actctcatcg gcgatggccg
     8041 gtacgaggac gccggcgcgt tgttgacacg tgccgccgac ctggagccct ggctgtccga
     8101 gtcctggttc aacctcgccc tgctgcacaa gttccggcac gactgggagc aggcgcgggc
     8161 ggcggggctc agggccgtgg cactgctcga ccgggacacc ggagcgcccg actggtggaa
     8221 cgtcggcatc gccgcgaccg ccctccagga ctggccgctg gcccggcgcg cctggcaggc
     8281 ctacgggctg cgggtgccgg ggccgcccaa cgactccggt gagcccgtcg gcatggacct
     8341 cggcagcgcg gccgtgcggc tgtccccgga gggggaggcc gaggtcgtgt gggggcggcg
     8401 gctggatccc gcgcggatcg aggtgttgtc catcccgctg ccgtcgtcgg ggcggcgctg
     8461 gggtgaggtc gtcctgcacg acggcgtgcc gcacggggag cggaccacgg ccgccgggca
     8521 cacctacccg gtgttcgacg agatcgagct gtgggcgccg tcgccggtgc cgacctgggt
     8581 ggtgctgctg gaggccgcga ccgagtcgga ccgggacgcg ctggagcagc tcgccgcgga
     8641 cgccgggttc gccgcggagg actggtcttc ttcggtgcgt ttgctgtgcc ggatgtgctc
     8701 ggagtcacgg atgccgtccg acgagggcga cggggagcat ctcgatccgc acgatcacag
     8761 cgagccgggg catcccgggc cgctggggca tcggacggac gggcagctgt gggttcccga
     8821 gcgggagtgc gggttggccg cgccggcttc gctggttcgg gggttgctgg acgggtgggt
     8881 cgccgacagt ccggattctc gggattggcg ggatttggaa gaggtctgct agatccgttg
     8941 tcgggtgcgg cgccgtcgtg gccgttcgcg cagttccccg cgcccgtgaa ggggcgcctg
     9001 ccccgtaccc tgtatcagca tcccggcttg gatttgttca ggaaggcgta cgtaacgtca
     9061 tggctcagca ggacaccgat cagcagcgcg cgggcgtgct ccccgtcgat gacgaggggt
     9121 acgtgatcga cacggaggac tgcgaggagc gcgaggcggc ctggcgggag cgggggacct
     9181 cgcggccgat cacggtggtc gggaacccgg tgctgcacaa ggagtgcaag gacgtcaccg
     9241 acttcggcga cgagctccag caactggtgg cggacatgtt cgcctcgcag cgcaccgccg
     9301 agggcgtggg cctggccgcc aaccagatcg gcgtcgacct gaaggtcttc gtctacgact
     9361 gcccggacga cgagggcgcc cggcacaccg gcgtcgtctg caaccccaag ctcgtcgaac
     9421 tgcccgccga gaagcgccgg ctggacgaca gcaacgaggg ctgcctgtcg gtgcccaccg
     9481 cgtacgcgcc gctcgcccgg cccgactacg ccgaggtgac cgggcaggac gagcagggca
     9541 acccgatccg ggtgcgcggc accgggtact tcgctcggtg tttgcagcac gagaccgacc
     9601 acctgtacgg ctacctgtac atcgaccgcc tctccaagcg ggaacgcaag gacgcgctgc
     9661 ggcagatggc cgagaacgag ccccggtacc ccgtcgtcgc gaacgactga gacctcacga
     9721 tcaccaggcg cacggcgtct gttcgggatt cccgtcctga acagacgccg ttcgtctgtg
     9781 ccgttcgcct gtccgtcgca cgttcgatcg cttctgctct cctggtgatc cggtaccagt
     9841 cacgcaacgg gaggttcccg gcccttgggg tagtgaatga agcaaatgcg ttcccagaac
     9901 ggtcagttgt agtgctgaat ggagggagcg gggcaacggc gcacgcccgg cacggaagga
     9961 ggggcgcccg cgccaactgg cggctgagag gggttagttc gtgcatgctt tgtcacacgg
    10021 caccacatcg acaccgacca ccatcgcggt tccaccgtcg ctctcccttc cggtgatcga
    10081 ggcggcgttt ccccggcaac tccacccgta ttggccgaag tgccaggaga agacccgggt
    10141 ctggctgctc gaaaagcggc tcatgcctgc ggacaaggtg gaggaatatg ccgacggcct
    10201 gtgctacacc gacctcatgg ccgggtacta catcggcgcc tccgacgagg tcatgcaggc
    10261 gatcgcggat tacagcgcct ggttcttcgt ctgggacgac cgtcacgacc gcgacatcgt
    10321 gcacggccgc cccctcgcct ggcggcggct gcgggaccgg ctgcactcgg ccctcgacac
    10381 tcccagggag cacctgcacc acgaggaccc actggtcgcc gggttcgcgg acagcgtgct
    10441 gcggctgtac gccttcctgc cggcgacgtg gaacctccgg ttcgcccggc acttccacga
    10501 ggtgatcgac gcctacgacc gggagttcca caatcgcacc cacggaatcg tgcccacggt
    10561 cgaggagtat ctccggttgc gccgactcac cttcgcccac tggatctgga cggatctgct
    10621 ggagccgacc gcgggatgcg aattgcccga cgccgtaagg aaacacccgg cctatcggcg
    10681 ggccgcgctg ctgagccagg agttcgccgc ctggtataac gacctctgct cacttccgaa
    10741 agaaatagcg ggcgacgagg tgcacaatct cggaataagt ctcatcaccc atgagcggct
    10801 gacgctggaa caggcggtcg cggaagtcag gagccgtgtc gagaactgca tcatggaatt
    10861 cctggatgtc gaacagacag cattacggtt cgccgacggc ctcgccgacg gcaccgtgcg
    10921 gggaaaagaa ctcagcgccg ccgtgcgggc ctgcctgagc aatatgcgga actggttcag
    10981 ctctgtctac tggttccatc acgagtccgg ccggtacatg gtcgacagct gggacgaccg
    11041 gtccacgccc ccgtacgtca acaacgaagc ggcaggtgag aaatgaccgt cgagtctgtg
    11101 aagcctgaag cccccctggt tccggagctg cgggaaccgc cccgggccag cggcggtgtc
    11161 cccgtcctgg ggcacggctg gaagctggtg cgcgacccgc tggcgttcat gtcccggctg
    11221 cgcgaccacg gcgacgtggt ccggctgaag ctcggaccga agacggtgta cgccgtcacc
    11281 accccggcgc tcaccggcgc gctggcgctg agcaacgact tcatcatcgc cgggccgctg
    11341 tgggagtccc tggagggcct gctcggcaag gagggcgtgg ccacggcgaa cggcccgcgg
    11401 caccggcgcc agcggcgcac catccagccc gccttccggc tcgacgccat ccccgcctac
    11461 gggccgatca tggaggagga ggcgcacgcg ctgaccgagc gctggaagcc ggggcagacc
    11521 atcgactgca cgtccgagtc cttccgggtg gccgtgcgca tcgcggcccg ctgcctgctg
    11581 cgcggcgact acatggacga gcgggcggag cggctgtgcg tcgcgctcgc cacggtcttc
    11641 cgcgggatgt accggcggat ggtggtgccg ctcggaccgc tctacaagct gccgctcccg
    11701 gccaaccggg aattcaaccg ggcattggcc gatttgcatc tcctggtgga cgagatcgtc
    11761 gccgagcgcc gcgcatccgg tcaaaagccg gacgatttgc tgacggcatt gctggaggcg
    11821 acggacgaga atggcgaccc catcggggaa caggagatcc acgaccaggt cgtcgcgatc
    11881 ctcacccccg gcagcgaaac cgtcgcctcc acgatcatgt ggctgctgca tatgctcgcg
    11941 gaacaccctg aacacgcgga ccgggtgcgc gacgaagtag aagccgtcac cggtgggaag
    12001 ccggtggcat tcgcagacgt ccgggggctc aggcacacca acaatgtcgt ggtcgagtcc
    12061 atgcgtttga gcccggccgt gtggattctg acgcggcggg cggtgcggga cacggaactc
    12121 ggcggatacc ggattccggc cggggcggac atcgtctaca gcccgtacgc gatccagcgc
    12181 gatccgaagt cgtacgcacg gaacctggac ttcgaccccg accgctggct tccggaccgg
    12241 gtcaaggacg tcccgaaaca cgccatgagc ccgttcagcg tgggcaaccg caagtgcccg
    12301 agcgaccact tctcgatggc tcagctgacg ctgatcacgg cggcgctggc caccaggtac
    12361 cgcttcgagc aggtggccgg ctcgaacgac agcacacgcg tcggcattac gctgcggccg
    12421 cacgacctgc gggtgcggcc ggtggtgagg tgagagccct tggcctcagg ccgcctccgg
    12481 gcccctgaac gtgcgccggt aggcgttcgg cgtcgtcccg atcgcccgga cgaagtggtg
    12541 gcgcagtgtg gccgcgttgc cgaaccctgt tcgaccggcg atcgcgtcca tcgtctcgtc
    12601 cgtcgcctcc agcagccgct gggccagcag cacgcgctgg cgcaggatcc agcggtaggg
    12661 agtcgtcccg gtctcctgct ggaagcggcg ggcgaaggtg cgcggggaca tgtgggcgtg
    12721 ggcggcgagc tgctcgacgg tgacctcctc gtcgagatgg cgctccatcc acgccagcac
    12781 gtcgacgatc gtgtcgccct cggggtgggg gagcgggcgc tcgatgtact gggcctggcc
    12841 gccgtcgcgg tgcggcggca ccaccatccg ccgggcgatc ttgttggcga cctcggagcc
    12901 ctgctccttg cgcaccaggt gcaggcaggc gtcgatgccg gcggccgtgc cggcggaggt
    12961 gatcaccggg tcctcgtcga cgtagaggac gtccggctcg acgatcacgc gcgggtactg
    13021 ccgggcgagg tccttcgcgt gcttccagtg cgtggcgcag cggcggccgt ccagcaggcc
    13081 ggccgcggcc agcacgaaga ccccggagca gacgctcagc acccgggcac cgcggtcgac
    13141 cccgcgccgc agggcggcca gcagctccgg ggggaagtcc cggtacgcgt agctgtgccc
    13201 ggcgggcacg gcgatcaggt cggccgtctc cagccgctcc aggccgtgct cggcctggag
    13261 cgagaagccc gagttcatgc gcagcaccgg gccctcggcc gaggccacgg cgaagtcgta
    13321 gaccggcagg ccttcatcgc tccggtcggt gccgaagacc tcgcacacca cacccagttc
    13381 gaaggggttc acgccgtcga gcagggcgac ggccacgttc tgcagcatgc ctccagtgtg
    13441 cctcgccggt ggcagtaatt cgagggtcta cggcagtact gccactgacg gtaaggagtc
    13501 atcggcgcga cagtggtgtc catggacacg aaccagacgc agacactcat cgcaatgatc
    13561 ttcgtactcg ggacgctggt cctcctggtc ctcccgtcag tgatcggcat cgtgcgcgac
    13621 cggcgcgtcg accgtcagat cagggaggcc caggagatcc gcgaaggcgt ggcggctcag
    13681 aagtcctcgt ccaggtcgac ggtgccctcc accgccacct ggtacgcgga gggccgccgc
    13741 tcgaagaagt tggtcaactc ctgaaccccc tggagctcca tgaaggagaa ggggttctcg
    13801 gagccgtaca ccggagcgaa gcccaggcgg gtgagccgct ggtcggcgac gcactccagg
    13861 tactgccgca tcgactcggt gttcatgccc gggaggccgt ccccgcacag gtcgcgcgcg
    13921 aactggagct cggcctcgac ggcctcgcgg agcatgtccg tcacctgctg ctggagctgg
    13981 tcgtcgaaca gctccggctc ctccttgcgg acggtgtcga ccacgtcgaa ggcgaacgac
    14041 atgtgcatcg tctcgtcgcg gaacacccag ttggtgccgg tggccagacc gtgcagcagg
    14101 ccccggctgc ggaaccagta cacgtacgcg aaggcaccgt agaagaacag gccctcgatg
    14161 cacgcggcga agcagatcag gttcagcagg aaacggcggc ggtcggcctg cgtctccagt
    14221 cggtcgagct ggtcgacctc ttctgttcca tcaaatgcag ccatccactt gaagcagaac
    14281 tcggccttct cgcggatgga gggaatgttc tcgacggccg cgaaggccgc cgcccggtcg
    14341 tcgtggtcgg ggaggtaggt gtccaggagc gtcagataga actggacgtg gacggcctcc
    14401 tcgaagagct gacggctcag atacagacgc gcctcggggg agttgatgtg cttgtacagc
    14461 gtcagcacca gattgttcgc gacgatcgag tcgcccgtgg cgaagaaggc gaccagccgg
    14521 ccgatcaggt gctgctcgtc gggggagagc ttggcgaggt cggcgacgtc cgagtggagg
    14581 tcgacctcct ccacggtcca ggtgttcttg atggcgtccc ggtagcgctc gtagaagtcc
    14641 gggtagcgca tggggcggag ggtcagctcg aagcccgggt cgagaaggtt ctgggtcata
    14701 acagtcggcg cgaagcgccg tcctccaggg gtggcggtcg ggtggcgggt gggaattact
    14761 ggcaggcctc gcaggactcg gggttttcca gggagcaggc gaccgcttcg gggtccgggg
    14821 tggcctgcgc ggggacagcg gcctgggcgg cgcgggcgat gcgggtcgcc gggcgcgagc
    14881 gcaggtagta cgtggtcttc agcccggact tccaggcgta ggcgtacatc gaggagagct
    14941 tgccgatggt cggcgtctcc aggaagaggt tcagggactg ggactggtcc aggaacgggg
    15001 tcctggccgc cgccatgtcg atcaggccgc gctgcgggat ctcccacgcc gtgcggtaga
    15061 gggcgcgcac gtcctcgggg atccaggcga agtcctgcac cgagccgttg gcctcgcgca
    15121 gggcctcccg gctgcgggcg tcccacacgc cgagccgctt gagctcctga accaggtagg
    15181 agttgacctg gaggaactca ccggacagcg tctcgcgctt gaacaggttg gacacctgcg
    15241 gctcgatgca ctcgtacacg cccgcgatcg aggcgatcgt ggccgtcggc gcgatggcga
    15301 ggagcaggga gttgcgcatg ccggtcgcgg cgacgcgctc gcgcagggcc gcccagcgct
    15361 ccggccaggt cagctccacg tcgtagtggt cggggtggag cacgcccttg gccgtacggg
    15421 tcttctccca ggccggcaac gggccgttgc gctcggcgag atcggcggag gcctcgtagg
    15481 cggcgagcat gatccgctcg gcgatgcggg tggacagtgc cttggcctcg ggcgagtcga
    15541 agggcaggcg cagcttgaag aagacgtcct ggaggcccat gactccgagg ccgacggggc
    15601 gccacctggc gttggaacgg cccgcctgct ccgtcgggta gaagttgatg tccacgaccc
    15661 ggtcgaggaa cgtcacggcg gtgcggacgg tctcgtccag ccgctcccag tcgatgtccc
    15721 cgccggcctg gtcgacgagc gcgccgaggt tgaccgaccc caggttgcag accgccgtct
    15781 ccccgtcgct ggtgacctcc aggatctccg tgcagaggtt ggacgagtgg acgacgtggc
    15841 ccggttcggc ggtctggttg gcggtgcgat tggcggcgtc cttgaaggtc atccagccgt
    15901 tgccggtctg cgcgagggta cgcatcatcc ggccgtacag ctcgcgtgcg ggcagcgtct
    15961 tcttcgccag gcccttcgcc tcggcggccc ggtacgcggc gtcgaactcc tcgccccaca
    16021 ggtcaaccag ctcgggcacg tccgcggggg agaacagcga ccactgcgcg tcggcgttca
    16081 cgcgccgcat gaactcgtcg ggcacccagt gcgcgaggtt caggttgtgc gtacggcggg
    16141 cgtcctcgcc ggtgttgtcg cgcagctcca ggaactcctc gatgtcggag tgccaggtct
    16201 ccaggtagac cgcggcggcg cccttgcggc ggccgccctg gttcacggcg gcgaccgagg
    16261 cgtcgagggt cttcaggaac gggacgatgc cgttggagtg gccgttggtg ccacggatca
    16321 gcgaaccccg cgcacggatg cgggagtagg cgatgccgat gccgccggcg tgcttcgaca
    16381 gccgcgccac ctggtggtac cggtcgtaga tcgagtccag ctcgtccttg ggggagtcga
    16441 gcaggtagca ggacgacatc tgggggtgtc gcgtgccgga gttgaagagg gtgggggagg
    16501 aggggaggta gtcgagccgg ctcatcagcc cgtagagagc ggcgacttcg tcgacggagc
    16561 ggcgagtgtc gtcctcggcg agaccggcgg cgacgcgcag catgaagtgc tggggcgtct
    16621 cgatcacctt gcgggtgatc gggtgccgga gcagatagcg gctgtgcagc gtacgcaggc
    16681 cgaagtagcc gaagcggtcg tcggcggccg tgtcgatcag ggcgtcgagg cgggcggcgt
    16741 ggacgcgcac gaactcggcg gtccggtcgg cgatgaggcc ctcccggtgc cccaccgcga
    16801 cggactcggt gaagcacgtg acgccctgtg aggctgcctc ggcgcggatc ccgatcgtca
    16861 gcaggcgtgc ggccagccgg gagtaggcgg gatcctcgga gatgaggccg gcggccgcct
    16921 ccgtcgccag ctcgcgcaac tccggctcgt cggcccgcgc ggaccggccg cgcagcgcgg
    16981 cggcggcgat ccggccggga tcggcgtcgg ggaggtcggc ggtcagctcg gtcagggtcc
    17041 gcagcagcgc ggcaccagga ccgtcgtgct cttcttcggc tgctgagacc ggatcggctg
    17101 gcgcgatggt cacgtggggc tctccctcgc tcggcacggg ggcctcgcag ggcagggggc
    17161 agcacgcgag cgcacgcggc gtcgcgtcca ccggcccatt ccacgaggcc cggacgtcag
    17221 gcacaccggc cggacggccg ggcgcgctgt cggcaggtcc tcggactgac tcccatacac
    17281 gcataaagag gcatgggtac accgttgcgg gacagttccg gattcgcacc ggattcccct
    17341 gcggcgacag cgagcacgag catacatctt gtgccgggtg gcgaaagcac ccctagatgt
    17401 agtgccgcga cggtttcacc tgcttctggc gaggatgcct cggcgtttac gccgggagga
    17461 atcgcctcct gtcggccgcg acgcggagcg tcgccgcgtc ggctctttgc ccggcgaggg
    17521 gcgcccgccc acggctgccc ggcggagccg gggaatgcga acagtcgtcc cgcgggtcac
    17581 ctgctgtggt gagtgcgggg cgaatagcgg ttgtgtgtgc ggatgtcgta ctacggtccg
    17641 atgtcatgag gctggtcgtg caggtgaagt tgctgccgac gcccgagcag gcgtcggcac
    17701 ttgaggcgac cctgcgcgcc tgcaaccggg ccgccaccta cgcttcgcag gttgccttcg
    17761 ccgagaacct caaggaccgc aacggtctgc agaaggaggt atacgcggac ctgaaggcca
    17821 cgttcgggct gtcggcgcag ccggcggtgc gggcagtgaa gaaggtcgtc gacgcctacg
    17881 ccaccctgaa ggccaacctt caggccggaa acctgggctc gcccacctcc aagcggcacc
    17941 gcagggcggt cggctcaccg atcgccttcc gcccggaggc ggcccagccg ttcgacgacc
    18001 gttgcctgtc gtggcagtac gacgcacgca cggtgtccgt ctggaccgtc gccgggcgga
    18061 tgaagggcat ccgctttgtc tgctcccccg agcagctcaa gaccctcgtg cagtaccgca
    18121 agggcgagag cgacctcgtc cagcgcggca ggaagtggtt cctgatcgcc acctgcgaca
    18181 tccccggccc ggggtgtacg agcctgccga ttggatcggg gtcgaccggg gcatcgtgaa
    18241 cctcgccacc accagcgacg gcaccaacca ccagggccgc cgcttgtccc gctaccggcg
    18301 ctggcaggcc cgcaaacgtg ccgaattcca ggccaggcgg ccccgctcgg ccacccgccg
    18361 cctcgcccgc cgcgcacaga aggaacgccg ccatgccacc catgtctcct catggccctt
    18421 ccaccagctc ggacaccacc tcgcctacaa agctcgtaag gccggggtgc cattcctgga
    18481 agtggacgca cgccatacct cgcagcgctg cccgcgctgc ggtcacaccg agcgggccaa
    18541 ccggcccacc cgggaccatt tccgctgtcg tcggtgcggg ctcgctggcc ccgccgacgt
    18601 cgtcgccggg gtcaacgtgc gcgaccgcgc acgctcggcg tgggcattcg tcaccatgcc
    18661 cgtcccacac ccggtctgac cggagagggg agatgcgacc cgtgaccgtc ctgtcgtagg
    18721 gggcagtcgg gagcgcgacg aggtgtgaac gaccgagcca acaagctcgg ccgttcaggg
    18781 ccgagaaggt gacagcgtca actcgtaggt gaggagagtg atgtcgtcga gctccggaat
    18841 cgggttccag tcgcgctccg gggcacggac gaagccgaga cgttcgtaga tgcggtgggc
    18901 ggcgtgcatg gtgcgctgcg tcgacaggac gacgcgaacg cagccgtccg tcgcgcgggc
    18961 gcggtcgacg caggcacgga cgagagcctc tccggcgccc tggccgcggg cctcgtgggc
    19021 gacggcgagc atccgtatct cggcctcccc gggaagggcg atgtcggcca tggggccgcc
    19081 ggaggggacg aaggtgacgc ccccgaggag gtgttcgccc cgggtggcca ccaggacgtc
    19141 cgcggcggcg gcccgcctgg ccacgtcctt gagttcgccg aggtaccagt cgctctcgcc
    19201 gaagtcgagg aggccgtcct ccaggtaggc ctgagcggtg atctcgccga gggcgtcgtg
    19261 ttcggcgggc ttcacccgcc ggatgaggat gtccatggtc cgagtgtgcg ggacgggtat
    19321 gacgacgggc cgccggttgt ccgccggcgg cccgtcgtca cctgcgactc agtgcgaggt
    19381 gcccgccgtc gccggcggaa gctccacctg gacgccgggg tcgcccgcgt ccgccgtgta
    19441 gtcctccggc ttggtctcgt cgatgccgtc gggggccttc agcgccctga ggacgaaggt
    19501 caggacgacg gtgacgacga cgttcaggac gaacgccgtg aggccgatgt agccgatctc
    19561 gccgatgccc gggatctcct tcgacgagcc gccgaagtgc ttctgggtcg gggaggcgac
    19621 gccgtacgcc gcgaccgtgc cgtagaccat gccgaccgcc cagcccgcga gcagcgccca
    19681 gcggtggaac cagcgggtga acaggccgcc gaccagggcc gggaaggtct ggaggatcca
    19741 gatgccgccg aggagctgga agttgatggc gaccgtcttg tccatggtga ggacgaaggc
    19801 cagcgcgccc accttcacca gcagggagac cagcttggag accttggtct cctgggcggg
    19861 cgtggcgtcg ggcttgatga agtccttgta gatgttgcgg gtgaagaggt tcgcggccgc
    19921 gatggacatg atggccgccg ggaccagggc cccgatgccg atcgccgcga aggccacgcc
    19981 cgcgaaccag tccgggaaca tggtctcgaa cagctgcggg atcgccagct gaccgttctg
    20041 caccttgatc ccggccgcga tcgccatgaa accgagcagc gcgagcaggc ccagcatcag
    20101 cgagtacagc ggcaggatcg tggtgttgcg gcggatcacc tcacggctcc gcgaggacag
    20161 cgtcgccgtg atcgagtgcg ggtacatgaa gagcgcgagc gcggagccca gcgccagggt
    20221 ggcgtacgtc cactgccccg cctccggcgg caccagcgca ccgcgcggcg cgcccgtcgc
    20281 cgggttcgtc tgaccgtacg cctcgccggc cctggcgaag atctcgtcga agccgcccag
    20341 cttgatcggg atgtagatga tcgccaccgc gatgacgatg tagatcaggg tgtccttcac
    20401 gaacgcgatc agcgccggcg cccgcagacc cgacgagtac gtgtaggccg ccagcacacc
    20461 gaaggcgatc agcagcggca ggtccttgat gaaccagttg gtgtcctcgc cgccgccgac
    20521 gcccatcacg tccagcacgg cctggatgcc gaccagttgg agcgcgatgt acggcatcgt
    20581 cgcgaggatg ccggtgaggg ccacggccag ggagaggccc ttggagccga agcggccgcg
    20641 cacgaagtcg gacgtcgtca cgtacccgtg cttgtgggag accgaccaca ggcgggggag
    20701 gaaggtgaag atcagcgggt acaccaggat ggtgtacggc acggcgaaga agccggccgc
    20761 gcccgccgcg tagatcgccg cggggacggc gacgaaggtg tacgccgtgt acaggtcgcc
    20821 gccgagcagg aaccaggtga cccaggtgcc gaacgagcgg ccacccaggc cccattcgtc
    20881 gaggctgtgc tcgttctcgg ccttgcgcca gcgcgcggcg aggaagccca tgaccgtgac
    20941 gagcaggaag aagaagatga agacggcgag tgcgacgccg ttcacgccgt ccttcactcc
    21001 gacgcaccgc ccttcgcggc agagcgggag cgctggtcac gctgccacag cttgtaggcg
    21061 atcatcgtca gcacggtgga gatcag
//
