LOCUS       NZ_CP023702            25858 bp    DNA     linear   CON 23-APR-2024
DEFINITION  Streptomyces nitrosporeus strain ATCC 12769 chromosome, complete
            genome.
ACCESSION   NZ_CP023702
VERSION     NZ_CP023702.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nitrosporeus
  ORGANISM  Streptomyces nitrosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7581562)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008704555.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:20:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,704
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,461
            CDSs (with protein)               :: 6,461
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 66 of 146
            Pseudo Genes (incomplete)         :: 106 of 146
            Pseudo Genes (internal stop)      :: 16 of 146
            Pseudo Genes (multiple problems)  :: 38 of 146
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 7245256
            Orig. end                         :: 7271114
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023702.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..25858
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /candidate_cluster_numbers="3"
                     /contig_edge="False"
                     /product="terpene"
                     /product="melanin"
                     /region_number="27"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /rules="melC"
                     /tool="antismash"
     cand_cluster    1..25858
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /detection_rules="melC"
                     /kind="neighbouring"
                     /product="terpene"
                     /product="melanin"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     cand_cluster    1..22227
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22227
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:12227](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12227)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(38..53)
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: medium,
                     score: 17.68"
                     /tool="antismash"
     misc_feature    complement(97..111)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 27.53"
                     /tool="antismash"
     misc_feature    98..112
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: medium, score: 25.19"
                     /tool="antismash"
     misc_feature    complement(121..135)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: weak, score: 22.6"
                     /tool="antismash"
     gene            165..1367
                     /locus_tag="CP967_RS32270"
                     /old_locus_tag="CP967_32355"
     CDS             165..1367
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017240857.1"
                     /locus_tag="CP967_RS32270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32355"
                     /product="glycoside hydrolase family 6 protein"
                     /protein_id="WP_150491355.1"
                     /transl_table=11
                     /translation="MRLRATLLGALPLACAAALLTAPATAAPGAAQAGDAQAGAAAGTH
                     RTRLYVPDANPGAYRQAVDLLRQKKLRDAAGILAMARTPHAVWFGDQSPAEVEREAARV
                     VREAARQRAVPLFALYNVPGRDCANYSGGGASTTAEYQAWIDAVARGIGGHDAMVVLEP
                     DSLALLPSDCGQDDGEGTKTKARYAEVNYAVDTLEPLARTKVYLDTGHQGWHSVNDIVP
                     RLLEGGVERATGVFTNASNYHTEDANSWYGTLISSCLAYVDTGGDSADCPNQWWPRNDA
                     QAWLDTHVDTDPALMKHFVTDSSRNGRGTWTAPAGKYTDAQEWCNPPDRGLGARPTTAT
                     GDPLHDARLWIKIPGESDGLCLRGTDGPEDPERGTVDPAAGAWFPQQALELVRFAQPPL
                     F"
     misc_feature    1541..1554
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.67"
                     /tool="antismash"
     gene            1748..3517
                     /locus_tag="CP967_RS32275"
                     /old_locus_tag="CP967_32360"
     CDS             1748..3517
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765698.1"
                     /locus_tag="CP967_RS32275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32360"
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="WP_150491356.1"
                     /transl_table=11
                     /translation="MSSQRDRAQLSLHDVSRTYGTRTVLDRVSLTVRPGEKAGVIGENG
                     SGKSTLLRLMAGAETPDDGDVTVRFPGGTGYLAQTLDLDPGATVQDAVDAAMGELREME
                     RRIRAAETLMSDTTPTGAQLAAYGDLLTAYEERDGYRADARADAAMHGLGLGRVGRDRA
                     LGTLSGGEQSRLALACVLAAGPELLLLDEPTNHLDAAAVGWLEDHLRAHRGTLVAVTHD
                     RAFLERITTVILEVDRDLRGVTRYGDGWDGYRTAKAAARRRRAQEHQEWLDELARTGEL
                     AEAAGRRLAGTGKDPRQGFGKHRRSHEAKLSGQVRAARTRLEALRRTPVPAPPVPLRFT
                     ADLTLAPAPVFGPAAPPGDGTGPGPAGTASSAGMLAALESVVVGGRPEAPRLDVPLLRV
                     GPGQRLLVTGPNGAGKTTLLRVLAGDLAPDSGTVRRAARTGYLPQELPVRPTRRSLLAV
                     FAAGLPGPADEHTGTLLDLGLFRPEDLDVPVAELSAGQRRRLALARLVTRPADLLILDE
                     PTNHLAPDLVEELEAALDRYPGAVVVVSHDRSFRSRFAGDRLELRGGRIAGGTGFPADP
                     YGPEGAPAPRTEV"
     misc_feature    complement(3770..3784)
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     misc_feature    3771..3785
                     /note="TFBS match to CelR, Cellobiose uptake repressor,
                     confidence: strong, score: 30.11"
                     /tool="antismash"
     gene            3811..4959
                     /locus_tag="CP967_RS32280"
                     /old_locus_tag="CP967_32365"
     CDS             3811..4959
                     /GO_function="GO:0004553 - hydrolase activity, hydrolyzing
                     O-glycosyl compounds [Evidence IEA]"
                     /GO_function="GO:0030246 - carbohydrate binding [Evidence
                     IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015656886.1"
                     /locus_tag="CP967_RS32280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32365"
                     /product="cellulose binding domain-containing protein"
                     /protein_id="WP_150491357.1"
                     /transl_table=11
                     /translation="MKSLIASLRGARTAVTALLVALATTAALGTLAAPAHAAAPICEQY
                     GTTVVQGTYVVQNNRWGTSAEQCVEATGSGFTLTRAEGSVPTDGAPKSYPSVFNGCHYT
                     NCSPGTALPARVDTISSAPSSIAYSYVANAVYNASYDIWLDPQPRTDGVNRTEIMIWFN
                     RVGPIQPIGSPVGTATVGGRVWEVWTGNNGGNDVISFLAPSAIPSWQFDVMDFVDATVA
                     RGMAQNSWYLTSVQAGFEPWQGGAGLAVGSFSSVIDTGGGTGGPENPEEPGNPPAGACR
                     VTYTANSWQTGFTADVKITNTGNAAVEDWELGFTLPSGQTVTQAWNATLTPATGAVTAR
                     GAAFNGLISAGASQSFGFQGTHPGTFTEPQEFTLNGESCAVS"
     misc_feature    3862..3864
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(5020..5430)
                     /locus_tag="CP967_RS32285"
                     /old_locus_tag="CP967_32370"
     CDS             complement(5020..5430)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044271.1"
                     /locus_tag="CP967_RS32285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32370"
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="WP_150491358.1"
                     /transl_table=11
                     /translation="MSEERQVGIVLVSHSGPVALAVAELARGLAAGGVTAPVAAAGGTS
                     AGGLGTSAELIAEAAREVDRGAGVALLADLGSAVLTVKSMLAEEGGLPEGAMLVDAPFV
                     EGAVAALVTASMGGDLATVAAAATDAYGYRKV"
     gene            complement(5427..6044)
                     /gene="dhaL"
                     /locus_tag="CP967_RS32290"
                     /old_locus_tag="CP967_32375"
     CDS             complement(5427..6044)
                     /EC_number="2.7.1.121"
                     /GO_function="GO:0047324 - phosphoenolpyruvate-glycerone
                     phosphotransferase activity [Evidence IEA]"
                     /GO_process="GO:0006071 - glycerol metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="dhaL"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765695.1"
                     /locus_tag="CP967_RS32290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32375"
                     /product="dihydroxyacetone kinase subunit DhaL"
                     /protein_id="WP_150491359.1"
                     /transl_table=11
                     /translation="MLDTDFFRRWMAATAAAVEREAERLTGLDSAIGDADHGSNMRRGF
                     GTVTAVLESESPATPGAVLVLAGRQLISTVGGASGPLYGTLLRRTGKALGESGEVSQGQ
                     LAEAFGAGVAAVARLGGAKAGDKTMLDALLPASRALADSAGAARDAARAGALGTVPLRA
                     RKGRASCLGEGSVGHQDPGAASAALLMEALAEAAGENGGDRA"
     gene            complement(6371..7054)
                     /locus_tag="CP967_RS32295"
                     /old_locus_tag="CP967_32380"
     CDS             complement(6371..7054)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044470.1"
                     /locus_tag="CP967_RS32295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32380"
                     /product="DUF3618 domain-containing protein"
                     /protein_id="WP_150491360.1"
                     /transl_table=11
                     /translation="MGSQPDELKAEVEDTRAHLARDVDRLADRVAPGKVARRKAGAARH
                     RLTGARERVMGAAGSARDATAENAQSLSESASGAAEQARETARHAAGQVGGTVRSAPGQ
                     VTEQTQGSPLAAGVIAFGAGMLAAALLPTTAAEERAGAQLRDHSDELLGPVRQAAQEAG
                     QEVKEEMRGPATEAVDSLRSTAEEAVQTTRQQAQESGQDAATGLREVGRDAAREAREEG
                     GRPSR"
     gene            complement(7030..7482)
                     /locus_tag="CP967_RS32300"
                     /old_locus_tag="CP967_32385"
     CDS             complement(7030..7482)
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019992874.1"
                     /locus_tag="CP967_RS32300"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32385"
                     /product="phage holin family protein"
                     /protein_id="WP_150491361.1"
                     /transl_table=11
                     /translation="MAISYAKNETARPAAPAAGSTQAPSSDPSLGELVGEISDDLTRLV
                     RTEIELAKAEVKQEAAQAGKAGGMLAGSGYAVHLVLLLGSLAGIFGLAHVVDIAWAALI
                     VTALWAVVGAVLFVTGRSRLKAVRVKPERTAQTLKEDAKWARNPTS"
     gene            complement(7486..8157)
                     /locus_tag="CP967_RS32305"
                     /old_locus_tag="CP967_32390"
     CDS             complement(7486..8157)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044468.1"
                     /locus_tag="CP967_RS32305"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32390"
                     /product="hypothetical protein"
                     /protein_id="WP_150491362.1"
                     /transl_table=11
                     /translation="MSDFDGANHSDSRASQAVPPAVRDRVGEGAGLVGDKANDVAGTAR
                     EQAADVAGEASARARDVAGELRGQLQEQARTQTQRLADNVRRLAGELQDMSERDGNDSS
                     AARAVRQIADGGHRAASRIEHRGPDGLVSDLQDFARRRPGAFLAGAALLGFATARIGKG
                     VKSADGGTGGPGPRPRGSAEKSGSGSAPLPQDATPSYGGAISAPMPAADPYPDPQRPSG
                     G"
     misc_feature    complement(8188..8198)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 20.07"
                     /tool="antismash"
     gene            complement(8378..9127)
                     /locus_tag="CP967_RS32310"
                     /old_locus_tag="CP967_32395"
     CDS             complement(8378..9127)
                     /NRPS_PKS="Domain: PKS_KR (10-176). E-value: 1.7e-14.
                     Score: 46.1. Matches aSDomain:
                     nrpspksdomains_CP967_RS32310_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003974282.1"
                     /locus_tag="CP967_RS32310"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32395"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_150491363.1"
                     /sec_met_domain="adh_short (E-value: 4.3e-31, bitscore:
                     106.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGSTDSAGRVAIVTGGSRGIGRAVSERLARDGAAVVVNYAGGTA
                     AARETVAAITAAGGRALPVQADVADEDAVAAMFDRAEGEFGGVDVVVHSAGRMALSTIA
                     DLDLGELDALHRTNIRGSFVVARQAARRLRRGGAFVGMSTSVVGTQFPAYGAYAASKGA
                     VEAMLLVLARELRGRDVTVNAVAPGPTATDLFLDGKTPEQIEELSRIPPLERLGTPEDI
                     ANVVSFLAGPQGHWVNGQTLRANGGLV"
     aSDomain        complement(8600..9097)
                     /ASF="KR domain putatively catalyzing L-configuration
                     product formation"
                     /ASF="catalytic triad S,Y,N inconclusive"
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP967_RS32310_PKS_KR.1"
                     /evalue="1.70E-14"
                     /label="CP967_RS32310_PKS_KR.1"
                     /locus_tag="CP967_RS32310"
                     /protein_end="176"
                     /protein_start="10"
                     /score="46.1"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VAIVTGGSRGIGRAVSERLARDGAAVVVNYAGGTAAARETVAAIT
                     AAGGRALPVQADVADEDAVAAMFDRAEGEFGGVDVVVHSAGRMALSTIADLDLGELDAL
                     HRTNIRGSFVVARQAARRLRRGGAFVGMSTSVVGTQFPAYGAYAASKGAVEAMLLVLAR
                     ELR"
     CDS_motif       complement(9014..9091)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CP967_RS32310_0001"
                     /evalue="2.00E-06"
                     /label="PKSI-KR_m1"
                     /locus_tag="CP967_RS32310"
                     /protein_end="38"
                     /protein_start="12"
                     /score="20.5"
                     /tool="antismash"
                     /translation="IVTGGSRGIGRAVSERLARDGAAVVV"
     misc_feature    9143..9159
                     /note="TFBS match to ZuR_variant_2, Zinc-responsive
                     repressor, confidence: weak, score: 16.07"
                     /tool="antismash"
     gene            9225..9956
                     /locus_tag="CP967_RS32315"
                     /old_locus_tag="CP967_32400"
     CDS             9225..9956
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF024701.4"
                     /locus_tag="CP967_RS32315"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32400"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150491364.1"
                     /transl_table=11
                     /translation="MAQTNEGLREALLAAAEEQLTASPDHDVATRAVCEAVGVTQPVLY
                     RLFGDKRGLLDALAEVGLHRYAKRKAALERTDDPVADLRAGWDDHLAFAAENPAVYRLM
                     FSPRPWADTAAREGVSRLLTAALTRCAAAGALRGDVEDAAALILSANTGLALNRIAQPG
                     VYGRDTVSDTLRDAVLAAVVTAPAPARTDDPVTEAAHRLDAQLRIGPPTALASEETALL
                     RVWLDRLARTGARPGDAPGAE"
     gene            complement(10001..11233)
                     /locus_tag="CP967_RS32320"
                     /old_locus_tag="CP967_32405"
     CDS             complement(10001..11233)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF040195.3"
                     /locus_tag="CP967_RS32320"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32405"
                     /product="hypothetical protein"
                     /protein_id="WP_167535482.1"
                     /sec_met_domain="T1TS (E-value: 2.4e-75, bitscore: 253.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTGTAWPSPHSTAPPSPPTRPRPCAGSPPARSSGRREPPSRRSCA
                     RGGPALFLEVALSTTDALALPFYCPIEPAIHPAADEAAHRAVGWIDAMGFARTGDEHAR
                     ALGTNSADFYARFAPHADLDRLWLAACWVYWGFAFDDARCDEGPLAADPAGFARMAAHT
                     QRALEIPGPLHTGDRYAAAVHDLGERFRACATPVQNRRFHHAHRAWLSGVQWQVGNRAT
                     GRMPVLDEYLTMRLHSAGGEPTYAMLEIVNGEEVPAREMDSPAVQALTEMAICVDALDN
                     DRHSFARESGRHQTDQNILTVLMAQDGSTPEQALYDAVALRDSVLCRFLELAERVRAHA
                     SRPLARYLDDLAHGIRGNIEWALSVPRYLGAGSGGLRTAPAPPVWAGSPLAGTLDPRRL
                     PTVSWWWQDLA"
     gene            complement(11124..12227)
                     /locus_tag="CP967_RS32325"
                     /old_locus_tag="CP967_32410"
     CDS             complement(11124..12227)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014058774.1"
                     /locus_tag="CP967_RS32325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32410"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_150491366.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 1.8e-50, bitscore:
                     170.3, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSPQALTTGALDLAGIRERVDAALADFLRRPSSRVPPQNRRGHRH
                     DLDRALTDYVLAPGKRIRPLLCVIGWQAAGGDGGEGEGEGEETVMRLAASLELFHAFAL
                     IHDDILDDSDTRRGLPSAHRAFAARHRGRPDADAFGRNLAVLLGDLALVRCDGILHTAG
                     FTERQRHAVLPLIDTMRNEVVLGQYLDLHTAGSPTDDIDRALTVIRLKTARYTVERPLQ
                     LGAALAGGDAQTLHACSAYALPLGEAFQLRDDLLGTFGDPSVTGKPVTEDLRSGKATVL
                     MALAVRLAAPRQAELLDRLVGNPRMDEEGAMAVRRVLEATGARATVEKMISDRYGMAVA
                     ALDRSPFSPHATEALRRIAAGAVVRTA"
     gene            complement(12267..13781)
                     /locus_tag="CP967_RS32330"
                     /old_locus_tag="CP967_32415"
     CDS             complement(12267..13781)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019062105.1"
                     /locus_tag="CP967_RS32330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32415"
                     /product="AarF/UbiB family protein"
                     /protein_id="WP_229888441.1"
                     /sec_met_domain="APH (E-value: 6.6e-06, bitscore: 24.8,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEHRARLLARVLAQLAGTEAAHTLLPRGRFAPSAENAGARRARH
                     AREALESLGPFYIKAGQMLATRPDFVPPEMIAEFEKLHDSVSPAPFAAFEPVLREELGP
                     LWHQRFSDIDTDHPLGTASLAQVYRAELPGGRHVAVKIQRPGVRESVHADMKLIRTLAR
                     FAARRATRFNDVIDVEAMLGVVFDAMRPELDFRKEARNMTEAAEAATGFDHIAVPDVVH
                     ATGRVLVQGLAPGTSVRDADRDAFTVEERRAIGQDLLAFMYRGYFVDRIFHGDPHPGNV
                     FVHPGQPATLIDWGMVGRIDRPMSTSILLLLLNLAMNDGAGTARAWIDMGSTTSWTRAA
                     AFAGDMAALVPQIATASLEELNFGVTLTAVLQHSTRRGIRTSPMVAILGKSFANIEGSI
                     RHLCPELSLIDIFSEELIGIVTDLVREALSPQQAVRTALELITAGAAAPQQLRGVTRDL
                     SNRDLGMRMTLNGPKNQSRPGLRIGAPEIGLSMAAALFWQHHAKSR"
     gene            complement(13857..14402)
                     /locus_tag="CP967_RS32335"
                     /old_locus_tag="CP967_32420"
     CDS             complement(13857..14402)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP967_RS32335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CP967_32420"
                     /product="hypothetical protein"
                     /protein_id="WP_150491367.1"
                     /transl_table=11
                     /translation="MVHVTEDLVDDALDRAGDFERGMRHSLSDALDDDRRRRDRDHDDH
                     DHRDHDDRHRDRGRDRDRDRDRDCGRDRDRDDGCDRDRHRDRDGNWDGDRDGPDRRPRA
                     TTVRRAGPPSREEEGLSALTERISLLADRLEQHRDDGRGMRTPGVVPPPRDAQDVDALR
                     ADLAALSARLDRLSDVAR"
     gene            complement(14531..14983)
                     /locus_tag="CP967_RS32340"
                     /old_locus_tag="CP967_32425"
     CDS             complement(14531..14983)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018540726.1"
                     /locus_tag="CP967_RS32340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32425"
                     /product="hypothetical protein"
                     /protein_id="WP_150491368.1"
                     /transl_table=11
                     /translation="MAAISQIIAHIVTADVEHASTGSWIYLGLGGREFSLDTHDVDFSR
                     GADACFLLGEESNVKYSDYNDPRTPPLSTEDLAHSPVYLRVETAGDGPAWCLEWVSVTV
                     NPDTSYRRRFIHPSLAGSAREHRIWLDTGYGKAVYLRPVDDAEPRH"
     cand_cluster    15373..25858
                     /candidate_cluster_number="3"
                     /contig_edge="False"
                     /detection_rules="melC"
                     /kind="single"
                     /product="melanin"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    15373..25858
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[20372:20858](+)"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      20373..20858
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="melC"
                     /neighbourhood="5000"
                     /product="melanin"
                     /protocluster_number="2"
     gene            complement(15898..16482)
                     /locus_tag="CP967_RS32345"
                     /old_locus_tag="CP967_32430"
     CDS             complement(15898..16482)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044262.1"
                     /locus_tag="CP967_RS32345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32430"
                     /product="TerD family protein"
                     /protein_id="WP_150491369.1"
                     /transl_table=11
                     /translation="MITLKKEDGPADLDGVTHLSIGVSWDPTSGSSGGVMGVLRRKTGT
                     DLDLIAIAMQGADPVRLAGLDSLDPLGNGSLLHSGDNQTGRGDGDDETVTVDFAKVPEN
                     ITSFVFVAAAYKKGSSFQKARNISFKVYDATGGSSQQVADIWPSLLSADNACAVAKAFR
                     VGSAWKLEVINVTGKIKQGNEQALMRFAVSK"
     gene            complement(16907..18391)
                     /locus_tag="CP967_RS32350"
                     /old_locus_tag="CP967_32435"
     CDS             complement(16907..18391)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044254.1"
                     /locus_tag="CP967_RS32350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32435"
                     /product="hypothetical protein"
                     /protein_id="WP_150491370.1"
                     /transl_table=11
                     /translation="MSHSPGSRRTARRQAAGALLAAFLLGFATPASAVSPAPAGSAASF
                     GPTPPHNPYAGPDGTATMHGDTGSSDTTPLAGPGAGTLKSSRTALASACPTVLAGFDGY
                     PVALCTPIFGQVPTVHLLDPGDGSSLASLQLTKGSLLGGVYAYIDHLDRLVVADGSRSL
                     LRVGHHRDAAGDWRLTVDRRLSLASVIPEGDAVTGLAPDWSGRVWFATGGGIVGTADDA
                     TGTVRALSLPAGERVANSISTAPEGTAVTTTHATYLLTADGTGAPRTVWRKEYDRGSAR
                     KPGLLSWGSGSTPTFFGPGTGTEYVTIVDNADTAANLKVYRTGDGSDVCSVPVLRAADG
                     PASENSPVGAGRSVFVAGTYGYPYPAVPEGAGPAVPASAGFTGGLSRVDVRPGGTGCDL
                     VWDNTVRSAAVPKLSTADGLLHTVVRDPLIPGTEGTSLLDPYRYAQIDPDSGQVVRSVR
                     TGVGSLYDSLQMAGTITRDGAYLQGTVTGVLRITAQ"
     misc_feature    19070..19085
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.4"
                     /tool="antismash"
     gene            complement(<19627..20168)
                     /locus_tag="CP967_RS34965"
                     /pseudo=""
     CDS             complement(<19627..20168)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044247.1"
                     /locus_tag="CP967_RS34965"
                     /note="frameshifted; incomplete; partial in the middle of a
                     contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /product="cytochrome P450"
                     /pseudo=""
                     /transl_table=11
                     /translation="MNTPSRVTGDEVRGAGSAGRGDGTGPAGRDGPDGHADLAGPSFRR
                     LPRAKRLAAFARLRQLVAPVRSMPRTGSQPPFHALVRHGT"
     gene            20373..20858
                     /locus_tag="CP967_RS32360"
                     /old_locus_tag="CP967_32445"
     CDS             20373..20858
                     /GO_function="GO:0005507 - copper ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0042438 - melanin biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     melanin: melC"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157950.1"
                     /locus_tag="CP967_RS32360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32445"
                     /product="tyrosinase family oxidase copper chaperone"
                     /protein_id="WP_150491372.1"
                     /sec_met_domain="melC (E-value: 3.4e-47, bitscore: 158.8,
                     seeds: 38, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDPTTPTTTAGPAGTPPSARRPGRRAALRTVFTAAAVAGTAGALA
                     PVLFKGTGTPPGGDRRQQAPERFSERYRGREIKGTLTAVVPAGGPARPDTAAAALAMDA
                     ADVTIDGRPLHLMRRADGSYLSAVNHYESFPTPLEAARAAVDELGEARLSATSPHTI"
     gene            20890..21750
                     /locus_tag="CP967_RS32365"
                     /old_locus_tag="CP967_32450"
     CDS             20890..21750
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157951.1"
                     /locus_tag="CP967_RS32365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32450"
                     /product="tyrosinase family protein"
                     /protein_id="WP_150491373.1"
                     /transl_table=11
                     /translation="MYSRKNQRDLTRTEKKRLVTAILELKRTGRYDEFVTMHREFYVTD
                     ADRRPRAAHMTPSFFPWHRRYLLEFEKALQEVDSGVSVPYWDWTRDNTPAASLWAEDFL
                     GGNGRRGDRQVMTGAFAYREGNWSIRAAITDDPFLRRDFGRPSAPVTLPSAADVDRALA
                     DPVYDTDPWNSVTPTGFRNRIEGWGIRGVRGVTNHNRVHRWVGGSMAGAASPDDPVFWL
                     HHAYVDLLWDRWQRAHPGSGYLPARPPAAGDPQRGRVFALDDPMPPWDVKPSQLLDHSG
                     LYRYV"
     gene            complement(21844..22128)
                     /locus_tag="CP967_RS32370"
                     /old_locus_tag="CP967_32455"
     CDS             complement(21844..22128)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044244.1"
                     /locus_tag="CP967_RS32370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32455"
                     /product="chaplin"
                     /protein_id="WP_150491374.1"
                     /transl_table=11
                     /translation="MSRISKAAAVVAGTGALIVGGAGFASADAGAEALAAHSPGVLSGN
                     AVQVPVHVPINVCGNTVDVIALLNPAFGNACANVSGSDSHHEGDYGYGY"
     gene            22764..24410
                     /gene="pgm"
                     /locus_tag="CP967_RS32375"
                     /old_locus_tag="CP967_32460"
     CDS             22764..24410
                     /EC_number="5.4.2.2"
                     /GO_function="GO:0004614 - phosphoglucomutase activity
                     [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="pgm"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012382164.1"
                     /locus_tag="CP967_RS32375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32460"
                     /product="phosphoglucomutase
                     (alpha-D-glucose-1,6-bisphosphate-dependent)"
                     /protein_id="WP_150491375.1"
                     /transl_table=11
                     /translation="MVHERAGQPAQPGDLVDVARLVTAYYSVRPDPADPAQRVAFGTSG
                     HRGSALAAAFNEDHIAATTQAICDYRSRQGTDGPLFLGADTHALSEPARVTALEVLAAN
                     GATVLIDSGDGYTPTPAVSHAILTHNRDREQHLADGIVVTPSHNPPADGGFKYNPPHGG
                     PAGSDATSWIQDRANALIEGGLKEVRRIPFARALAADTTGRYDFLTAYVDDLPAVLDLD
                     AVRDAGIRIGADPLGGASVAYWGRIAERHRLDLTVVNPLADPTWRFMTLDWDGKIRMDC
                     SSPYAMASLIEQRDAYTLATGNDADADRHGIVTPDGGLMNPNHYLAVAIRYLCSHRADW
                     PAGAGIGKTLVSSSMIDRVAADLGRPLVEVPVGFKWFVDGLFGGTLGFGGEESAGASFL
                     RRDGRVWTTEKDGILLALLASEITAVTGSTPSQHYRELTDRFGDPAYARVDAPATREEK
                     AVLAALSPEQVTAGTLAGEPVTAVLTAAPGNGAAIGGLKVCTDSAWFAARPSGTEDVYK
                     VYAESFQGPGHLSEVQDEARALVSDALGRSS"
     misc_feature    complement(24708..24728)
                     /note="TFBS match to NrtR, NAD synthesis repressor,
                     confidence: weak, score: 18.51"
                     /tool="antismash"
     gene            24768..25262
                     /locus_tag="CP967_RS32380"
                     /old_locus_tag="CP967_32465"
     CDS             24768..25262
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014157967.1"
                     /locus_tag="CP967_RS32380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_32465"
                     /product="SHOCT domain-containing protein"
                     /protein_id="WP_190175127.1"
                     /transl_table=11
                     /translation="MPVGPVEYLVVTFPGSRFADAIAPVLADAVSSEAVRILDLTFART
                     AQDGALEHVGLSELDPEGAVAFEKPADSGVRAPDLTRTGALAGLPAGSCAALILWEDLW
                     SVPLTHAVRAAGGRLVAHERVPVDGEDDVITLLERLAALREKGELTDAEFAAQKTRILA
                     D"
ORIGIN
        1 cccggatcgc ttccgggtgc tcacggccgc tcccggggtg accacgaagt aacacccgca
       61 acagtcttga cgcatacatg gcgctcagga acgctcatgg gagcgctccc gcacccttcg
      121 gtgggggcgc tcccgcatgt tcaccgcgac cgagggacgg acccatgcgc ctcagagcga
      181 ccctgctagg agccctgccg ctcgcctgcg cggcggccct gctcaccgcc ccggccaccg
      241 cggcccccgg tgccgcgcag gccggtgacg cacaggccgg cgcggccgcc gggacgcacc
      301 gcacccggct gtacgtgccc gacgccaacc ccggcgcgta ccgccaggcc gtggacctgc
      361 tgcggcagaa gaaactccgg gacgccgccg gcatcctggc catggcgcgc accccgcacg
      421 ccgtgtggtt cggggaccag agcccggccg aggtcgagcg ggaggccgca cgcgtcgtca
      481 gggaggcggc caggcagcgg gccgtgcccc tcttcgccct gtacaacgtc cccggccgcg
      541 actgcgccaa ctactccggc ggcggcgcct ccacgaccgc cgagtaccag gcgtggatcg
      601 acgccgtggc ccggggcatc ggcggccacg acgccatggt cgtcctggaa ccggactcgc
      661 tcgccctgct gccctcggac tgcgggcagg acgacggcga gggcacgaag acgaaagccc
      721 gctacgccga ggtgaactac gcggtcgaca cccttgagcc gctggcccgc accaaggtct
      781 acctcgacac cggccaccag ggctggcact ccgtcaacga catcgtcccc cgcctgctgg
      841 agggcggtgt ggagcgcgcc accggagtct tcaccaacgc ctccaactac cacaccgagg
      901 acgccaactc ctggtacgga acgctgatct cctcctgcct ggcctacgtg gacaccggcg
      961 gggacagcgc cgactgcccg aaccagtggt ggccccgcaa cgacgcccag gcatggctgg
     1021 acacccacgt ggacaccgac cccgccctga tgaagcactt cgtcaccgac tccagccgca
     1081 acggccgggg cacctggacc gcgcccgccg gcaagtacac ggacgcccag gaatggtgca
     1141 acccgccgga ccggggcctg ggcgcccggc ccaccaccgc cacgggcgac ccgctgcacg
     1201 acgcccggct gtggatcaag attcccgggg aatcggacgg actctgcctg cggggtacgg
     1261 acggccccga ggaccccgag cgcgggacgg tcgacccggc agccggagcg tggttccccc
     1321 agcaggctct ggagctggtg cgtttcgcac agcccccgct gttctgacag ggggacggca
     1381 cgcccgtggg gctgcctgcc gcgccgacgg cgggcagccc cgcgaagtgg ccgtcacccc
     1441 gggagcggcg ggaccggacc ggccccgccg ctcccgggcg ggcccgcgcg ggtccgccgt
     1501 gaatcggggt acctcctttc cgcccgtggt tacactgaac cgcatgggca ggcactactt
     1561 ctttctctga gcaccggcca ggacgccgcc gtgtgacgca cgacgtcacc gggtgacccc
     1621 gggggtcact tcgcgccgca gtccttcccg ctgtccgacg accccgcccc gccgggtgtc
     1681 ccgcgcgccc ttcccggcgc cccgtgacgc gcggccgagg gcctgtcacc tcagggaaac
     1741 cccacccatg tcctcccagc gcgaccgcgc ccagctgtcc ctgcacgacg tctccaggac
     1801 gtacgggacc cggaccgtcc tcgaccgtgt ctccctcacc gtccgccccg gcgagaaggc
     1861 cggggtcatc ggtgagaacg gctccgggaa atccaccctc ctccgcctca tggcgggcgc
     1921 cgagaccccg gacgacggtg acgtcaccgt ccgcttcccc ggtggcaccg gctatctcgc
     1981 ccagaccctc gacctcgatc cgggcgccac cgtccaggac gccgtcgacg cggcgatggg
     2041 cgaactccgc gagatggaac ggcggatcag ggccgccgag acactgatgt ccgacaccac
     2101 ccccaccgga gcccagcttg ccgcctacgg tgacctgctg accgcctacg aggaacgcga
     2161 cggctaccgg gcggacgcga gggccgacgc cgccatgcac ggcctcggac tcggccgcgt
     2221 cggccgcgac cgggccctgg gcacactctc gggaggcgag cagtcacggc tggccctcgc
     2281 ctgtgtgctg gccgcaggcc ccgaactgct gctgctcgac gaacccacca accacctcga
     2341 cgccgcggcg gtcggctggc tggaggacca cctgcgcgcc caccgcggca cgctggtcgc
     2401 cgtcacgcac gaccgggcgt tcctggaacg gatcacgacc gtgatcctgg aggtggaccg
     2461 ggacctgcgc ggtgtcaccc ggtacggaga cggctgggac ggctaccgca ccgccaaggc
     2521 cgccgcccgc cgccgccggg cgcaggagca ccaggaatgg ctggacgaac tggcccgcac
     2581 cggggaactg gccgaggccg cgggccgccg gctcgcgggc accggcaagg acccccgcca
     2641 gggcttcggc aagcaccgca ggtcccatga ggccaaactg tccgggcagg tcagggcggc
     2701 caggacccgg ctggaagccc tgcgccgcac gcccgtaccc gccccgcccg tgccgctgcg
     2761 cttcaccgcg gatctcaccc tcgccccggc ccccgtcttt ggccccgccg cgcccccggg
     2821 cgacggcacc ggacccgggc ccgccggcac cgcgagctcc gccgggatgc tcgccgcact
     2881 cgaatcggtc gtcgtcggcg gccggccgga ggcgccccgg ctggacgtgc ccctgctgcg
     2941 cgtcgggccc ggacagcggc tcctggtcac cgggcccaac ggcgcgggga agaccaccct
     3001 gctacgggtc ctcgccggcg acctcgcccc cgactccggc acggtccgcc gtgcggcccg
     3061 gaccggctac ctcccgcagg agctgccggt ccggcccacc cgccgttccc tgctcgccgt
     3121 cttcgccgcc gggctgcccg gccccgccga cgaacacacc ggcaccctgc tggacctcgg
     3181 cctgttccgc ccggaggacc tggacgtccc ggtcgccgag ctgtcggccg gacagcggcg
     3241 ccggctcgcc ctggcacggc tggtgaccag gcccgcggac ctgctgatcc tcgacgagcc
     3301 gaccaaccac ctcgcgccgg acctggtcga ggaactggag gcggcactcg accggtaccc
     3361 gggtgccgtg gtggtcgtct cccacgaccg cagcttccga agccgcttcg ccggggaccg
     3421 cctcgaactg cgcggcggcc ggatcgcggg aggaaccggc ttcccggcag acccctacgg
     3481 cccggagggc gcccccgccc cgcgtacgga ggtgtagagc cgctccacga agacgcgccg
     3541 gcccgccacc agccgctcgg cggtctcttc cggtgtgctc cgggcgaacc gcgcgcagaa
     3601 gctctccccg caaggatcca cgaggcccgc cccgcctccc cgtcccctcc ctcctcgtcc
     3661 cccggtccgg tgtcacggcg gaccggggcc ctccgcttcg gcggttgtta cggaccggcc
     3721 ccttgtgggg agccccggcc gccccatagg ttccacgccg gggcggcata tgggagcgct
     3781 cccatcatcg ggtcctaccg gaaggacagc atgaagagcc tcatcgcttc cctgcgggga
     3841 gcgcgcacag ccgtgaccgc gttactcgtg gcactggcca cgaccgcggc cctcggcacc
     3901 ctcgccgcac ccgcccacgc ggccgcgccg atctgcgagc agtacggcac gacggtcgtc
     3961 cagggcacct acgtggtcca gaacaaccgc tggggaacct cggccgaaca gtgcgtcgag
     4021 gccaccggga gcggcttcac cctcacccgg gccgagggat ccgtgccgac cgacggtgca
     4081 cccaagtcgt acccctcggt gttcaacggc tgccactaca cgaactgctc acccggcacc
     4141 gccctgccgg cccgggtgga caccatcagc agcgcgccga gcagcatcgc gtacagctat
     4201 gtcgccaacg cggtctacaa cgcgtcgtac gacatctggc tcgacccgca gccgaggacc
     4261 gacggcgtca accgcaccga gatcatgatc tggttcaacc gggtcggtcc catccagccg
     4321 atcggctcac ccgtcggcac ggccaccgtc ggcggccgcg tctgggaggt ctggaccggc
     4381 aacaacggcg gcaacgacgt gatctcgttc ctggcaccgt ccgcgatccc cagctggcag
     4441 ttcgacgtca tggacttcgt cgacgcgacc gtggcgcggg ggatggcgca gaactcgtgg
     4501 tacctgacca gcgtccaggc cggtttcgaa ccgtggcagg gcggcgccgg gctggcggtc
     4561 ggttccttct cctcggtcat cgacaccggc ggtgggacgg gcgggccgga gaacccggaa
     4621 gagccgggga acccgcccgc cggcgcctgc cgggtcacct acacggcgaa ctcctggcag
     4681 accggtttca ccgccgacgt caagatcacc aacaccggga acgcggcggt cgaggactgg
     4741 gagctcggct tcaccctgcc gtccggacag accgtcaccc aggcgtggaa cgccaccctc
     4801 accccggcca cgggtgcggt gaccgcgaga ggtgcggcct tcaacggact gatctccgcg
     4861 ggagccagtc agtcgttcgg cttccagggc acgcaccccg gtaccttcac cgagccgcag
     4921 gagttcacgc tcaacggtga gagctgtgcc gtgagctgac gcttcaccgc ccgtggcggc
     4981 gccgttcgcc ccgtaccgcg cacggggcga acggcgcggt cacaccttgc ggtagccgta
     5041 cgcgtccgtg gccgcggccg ccaccgtcgc caggtctccg cccatcgacg cggtcaccag
     5101 ggccgctacc gcgccctcga cgaacggcgc gtccaccagc atggcgccct ccggcagccc
     5161 gccctcctcc gccagcatgg acttcacggt cagtaccgca ctgccgaggt ccgccagcag
     5221 cgccacccct gcgccccggt cgacttccct ggcggcttcc gcgatcagtt ccgcgctcgt
     5281 ccccagaccg ccggccgagg tccccccggc cgccgcgacc ggcgcggtca cgcccccggc
     5341 ggccagcccc ctggccagtt cggccaccgc cagggccacc ggcccgctgt gcgagaccag
     5401 gacgatcccg acctgcctct cctcgctcat gcccggtcac cgccgttctc cccggcggct
     5461 tcggcgagcg cctccatcag cagggcggcc gaggccgccc ccggatcctg atggccgacg
     5521 ctgccctcgc ccagacaact cgccctgccc ttgcgcgccc gcagggggac ggttcccagc
     5581 gcgccggccc gtgccgcgtc gcgggccgcg ccggccgagt ccgccagcgc ccgggaagcc
     5641 ggcagcagcg cgtcgagcat cgtcttgtcc ccggccttcg ccccgcccag ccgagccacc
     5701 gccgccacac cggcgccgaa cgcctcggcc agctgcccct gactcacctc tcccgactca
     5761 ccgagcgcct ttccggtacg ccgcagcaag gtgccgtaca gcggccccga agccccgccc
     5821 accgtggaga tcagctgccg tcccgcgaga accaggaccg cccccggcgt cgcgggcgac
     5881 tccgactcca gtacggcggt caccgtgccg aagccccgcc gcatgttgct gccgtgatcg
     5941 gcgtccccga tcgccgagtc gagtccggtc agccgttccg cctcccgctc gacggcggcc
     6001 gccgtggccg ccatccaacg gcggaagaag tcggtgtcga gcacatgacc tcctgttcgt
     6061 cagacgcgtc cgctgctcac acgttcgctg gtcacgtgcc cgctggccac gtgtccgcgt
     6121 tcacccgtgc tcgccgcccg cacgtgctcg ccgcccaccg tatccaccgg ccaccgcccg
     6181 ggccccgccc cgcgggtccg cgccgcccgt acccgtgtgc ggcacggatc ctcaccggcg
     6241 ccggaggacg gcgcgcacgg gcgcccgtcc gggaggacag cccagggctt gcggggaagc
     6301 atcacctcgt ttccccgcaa gccctgggcc gggacgggct cgcccggctc ccgcggatcg
     6361 ccggaaggcg tcagcgggag ggccgcccgc cttcttcccg cgcttcccgg gcggcgtccc
     6421 ggcccacttc gcgcagaccg gtggcagcgt cctggccgga ttcctgagcc tgctgcctgg
     6481 tcgtctgcac cgcttcctcg gccgtactcc gcagcgaatc gacggcctcc gtggccggac
     6541 cgcgcatctc ttccttcacc tcctggcccg cctcctgggc ggcctgcctg acagggccga
     6601 gcagttcgtc ggagtggtcg cggagctgcg cgccggccct ttcctcggcc gccgtcgtgg
     6661 gcagcagtgc ggcggcgagc atgccggcac cgaaggcgat gacacccgcg gcgagcgggc
     6721 tgccctgtgt ctgctcggtc acctggcccg gggccgagcg tacggtcccg ccgacctggc
     6781 cggccgcgtg ccgggctgtc tcgcgtgcct gttccgctgc ccctgaagcg ctctccgaga
     6841 gactctgcgc gttctccgcg gtggcgtccc gggcactgcc cgccgcgccc atcacccgtt
     6901 cacgtgctcc cgtcagccgg tgccgggcgg caccggcctt gcggcgtgcg accttcccgg
     6961 gagcgaccct gtcggcgagc cggtccacat cacgggccag atgcgcgcgg gtgtcctcca
     7021 cctcggcctt caactcgtcg ggttgcgagc ccatttcgcg tcctccttca gtgtctgcgc
     7081 ggtccgctcg ggcttgacgc gcaccgcctt gaggcggctg cggccggtca cgaacagcac
     7141 cgcgcccacg acggcccaga gcgcggtcac gatgagcgcg gcccacgcga tgtcgaccac
     7201 gtgcgcgagg ccgaagatgc cggccaggct gcccagcagg agtaccaggt gtacggcgta
     7261 gccggagccg gcgagcatgc cgcccgcctt ccccgcctgg gccgcttcct gtttcacctc
     7321 ggctttcgcc agttcgatct cggtgcgcac caggcgtgtg aggtcgtcgc tgatctcgcc
     7381 gaccagctca ccgagggacg gatccgatga gggcgcctgg gtggagccgg cggccggggc
     7441 ggccggccgg gcggtctcgt tcttcgcgta tgagatggcc acggctcaac cccctgacgg
     7501 cctctgcggg tccggatacg gatcggccgc gggcatcggg gccgagatcg cgcccccgta
     7561 ggagggggtg gcgtcctggg ggagcggggc ggagccgcta ccgctcttct cggcggagcc
     7621 gcgaggacgt ggccccggcc cgccggtgcc gccgtccgcg gacttgacgc cctttccgat
     7681 gcgggcggtg gcgaagccca ggagcgcggc acccgccagg aaggcgccgg ggcgccggcg
     7741 ggcgaagtcc tggaggtcgc tgacgaggcc gtcggggccg cggtgttcga tgcgggacgc
     7801 cgcgcggtgc ccgccgtccg cgatctggcg cactgcccgt gcggccgacg agtcgttccc
     7861 gtcgcgctcg ctcatgtcct ggagctcgcc ggccagccgc cggacgttgt cggccaggcg
     7921 ctgcgtctgc gtccgggcct gttcctgaag ctggccccgc agttcgcccg cgacgtcccg
     7981 ggccctggcc gaagcctcgc ccgcgacatc ggccgcctgt tccctggcgg ttccggccac
     8041 gtcgttcgcc ttgtcgccga ccagccccgc cccctcaccg actctgtcgc gaacagccgg
     8101 tggtacggct tgagatgctc tgctgtccga gtggttcgca ccgtcgaaat cgctcaatgt
     8161 tcctcctcgg tcggtcctgc gcgaggtgtc acatggcaat gacgcccgag aacgccactc
     8221 cttccatcat ggcaaccagt gagatatgcg caaaaggcgg aaatgtgcgc ttctccaggc
     8281 cctgtcgaga agggagacgc gaggccggag gggctggcgg ccggaccgtg cgcggggccg
     8341 ccccggtgct ccgtacgaag ccggacgggg cggcctttca gaccaggccg ccgttggccc
     8401 ggagcgtctg tccgttgacc cagtgcccct gcggtccggc gaggaaggac acgacgttcg
     8461 cgatgtcctc gggcgtaccc agccgctcca gcggcgggat cctgctcagt tcctcgatct
     8521 gttccggggt cttcccgtca aggaagagat ccgtggccgt cgggccgggg gcgacggcgt
     8581 tgacggtgac gtcccggccc cgcagctcgc gggcgagaac cagcagcatg gcctccaccg
     8641 cccccttgct cgccgcatag gcgccgtacg ccgggaactg cgtaccgacc acggatgtcg
     8701 acatcccgac gaacgcgccc ccgcgccgca ggcgccgggc ggcctgccgg gccacgacga
     8761 aagaaccgcg gatgttcgta cggtggaggg cgtccagctc ccccaggtcc aggtccgcga
     8821 tggtggacag ggccatccgc cccgcggagt gcacgacgac gtcgacgccg ccgaactccc
     8881 cctccgcgcg gtcgaacatg gccgccaccg cgtcttcgtc cgccacgtcc gcctggacgg
     8941 ggagcgcccg cccgcctgcc gcggtgatcg ccgccaccgt ctcccgggcg gcggcggtgc
     9001 cgcccgcgta gttcaccacg acggccgccc cgtcgcgtgc cagccgctcg gagacggctc
     9061 tcccgatacc gcgtgagcca ccggtgacga tcgcgacgcg tccggcgctg tccgtgcttc
     9121 ccgtcatgac ctgccctttt cgtcgatatg agataagcat ttctttgata cgaccaacat
     9181 agcacggata gtttcgttga tattccatgc gttacgctgt gtccatggca cagacgaacg
     9241 aggggcttcg tgaggcactg ctcgccgcgg cggaggaaca gctcaccgcc tccccggacc
     9301 acgacgtcgc cacacgcgcc gtgtgcgagg cggtgggtgt gacccagccc gtgctctacc
     9361 gcctcttcgg ggacaaacgc ggcctcctcg acgccctggc cgaagtgggg ctgcaccggt
     9421 atgcgaagcg gaaggccgca ctggagcgga ccgacgaccc ggtggcggac ctgcgtgccg
     9481 ggtgggacga ccacctggcg ttcgcggccg agaaccccgc ggtctaccgg ctgatgttct
     9541 ccccccgccc ctgggcggac acggctgccc gcgaaggcgt cagccggctc ctgaccgccg
     9601 ccctgacccg gtgcgccgcc gccggggcgc tgcgcggcga cgtcgaggac gcggcggccc
     9661 tgatcctctc cgccaacacc ggcctcgcgc tgaaccgcat cgcccagccc ggggtctacg
     9721 gccgggacac cgtgtccgac accctccggg acgccgtgct cgcggccgtg gtgaccgcgc
     9781 cggcccccgc caggacggat gaccccgtga ccgaggccgc gcaccggctc gacgcgcagc
     9841 tgcggatcgg cccgcccacg gcgctggcct ccgaggagac cgcgctcctg cgggtctggc
     9901 tcgaccgcct cgcccggacg ggcgcccggc ccggggacgc acccggggcg gagtgatccc
     9961 cgggccgcca cggccccggt ccccctcccg cccgggcctc tcaggcgagg tcctgccacc
    10021 accacgaaac cgtgggcagc cgccggggat ccagcgtccc ggccagcggg gagccggccc
    10081 agaccggagg ggcgggagcg gtacggagac cgccggaccc ggcgccgagg taccgcggca
    10141 cgctcagggc ccattcgatg ttgccgcgga tgccgtgggc gagatcgtcg aggtaccgcg
    10201 cgagcggacg gctcgcgtgc gcccgtaccc gctcggcgag ttcgaggaag cggcacagga
    10261 cgctgtcgcg cagggcgacg gcgtcgtaca gggcctgttc gggcgtgctg ccgtcctggg
    10321 ccatcagcac ggtgaggatg ttctggtcgg tctggtggcg tcccgactca cgggcgaagg
    10381 agtgccggtc gttgtcgagg gcgtcgacac agatggccat ttcggtgagt gcctggacgg
    10441 cgggcgagtc catctcccgg gcaggcacct cttcgccgtt gacgatctcc agcatggcgt
    10501 acgtgggctc cccgccggcg gagtgcagcc gcatggtgag gtactcgtcg agcacgggca
    10561 tccggccggt ggcccggttg cccacctgcc actgcacccc cgagagccag gcccggtggg
    10621 cgtggtggaa gcgccggttc tggacgggcg tggcgcaggc gcggaagcgc tccccgagat
    10681 cgtgcacggc ggcggcgtag cggtcgccgg tgtgcagggg gccggggatc tccagggcgc
    10741 gctgggtgtg cgcggccatc cgggcgaaac cggcggggtc cgcggcgagg ggcccctcgt
    10801 cgcagcgcgc gtcgtcgaag gcgaaccccc agtagaccca gcacgcggcg agccagaggc
    10861 ggtcgaggtc ggcgtgagga gcgaagcgcg cgtagaaatc ggcgctgttg gtgcccaggg
    10921 cgcgggcgtg ctcgtccccg gtccgggcga agcccatcgc gtcgatccag ccgacggcac
    10981 ggtgcgcggc ctcgtcggcc gccgggtgga tggccggttc gatggggcag tagaacggca
    11041 gggccagggc gtcggtggtg ctcagggcta cctccaggaa gagcgcggga ccaccccgtg
    11101 cgcacgagcg gcgcgagggg ggttcacgcc gtccggacga ccgcgccggc ggcgatccgg
    11161 cgcagggcct cggtcgcgtg gggggagaag ggggagcggt cgagtgcggc gacggccatg
    11221 ccgtaccggt cactgatcat cttctcgacg gtcgcacgcg ccccggtggc ctccaggacg
    11281 cggcgcaccg ccatggcccc ctcctcgtcc atccgggggt tgccgaccag ccggtccagc
    11341 agttccgcct gccgcggagc cgcaagccgg acggccaacg ccatcaggac ggtggccttg
    11401 cccgaccgca ggtcctcggt gaccggcttg ccggtgaccg agggatcgcc gaaggtgccg
    11461 aggaggtcgt cccggagctg gaaggcctca cccagcggaa gggcgtaggc ggagcaggcg
    11521 tggagcgtct gcgcgtcgcc cccggcgaga gcggcaccga gctgcaaggg gcgctcgacg
    11581 gtgtaccggg ccgtcttgag gcggatcacg gtgagggcgc ggtcgatgtc gtccgtgggg
    11641 gacccggcgg tgtgcaggtc caggtactgc ccgagcacga cctcgttgcg catcgtgtcg
    11701 atcaggggga ggaccgcgtg acgctgccgc tcggtgaagc cggccgtgtg cagtatcccg
    11761 tcgcaccgta cgagcgcgag atcgcccagg aggacggcga ggttccggcc gaacgcgtcc
    11821 gcgtcgggcc ggccgcggtg gcgggcggcg aaagcccggt gggcgctggg cagtccgcgg
    11881 cgggtgtcgc tgtcgtccag gatgtcgtcg tggatgagcg cgaaggcgtg gaacagctcc
    11941 agtgacgccg cgagccgcat gaccgtctcc tcgccctcgc cctcgccttc gcccccgtca
    12001 ccgcccgccg cctgccagcc gatgacgcag agcaggggcc tgatgcgctt tcccggggcg
    12061 aggacgtagt cggtgagtgc ccggtcgagg tcgtgccggt ggccccggcg gttctgcggc
    12121 gggacacggg aggaggggcg gcgaaggaag tcggcgagag cggcgtcgac gcgctcccgg
    12181 atgccggcga ggtcgagtgc tccggtcgtc agggcctgcg ggctcatggg cgggctccat
    12241 ggggtggggg tgcgggcgta gaggtgtcac cggcttttcg cgtggtgctg ccagaacagg
    12301 gcggccgcca tggacagccc gatctccggt gccccgatac ggagtcccgg ccgggactgg
    12361 ttcttcgggc cgttgagggt catccgcatg ccgaggtcgc ggttggacag gtcccgggtg
    12421 acgccgcgca gctgctgggg ggcggcggcg cccgcggtga tcagttccag cgctgtgcgt
    12481 acggcctgct ggggggagag ggcctccctg accaggtcgg tgacgatccc gatcagttcc
    12541 tcggagaaga tgtcgatcag ggagagctcg gggcacagat ggcggatcga cccctcgatg
    12601 ttggcgaacg acttgccgag gatggcgacc atggggctgg tgcggatccc ccggcgggtc
    12661 gagtgctgga gcacggcggt cagggtgaca ccgaagttga gctcctccag cgacgccgtg
    12721 gcgatctgcg gtacgagagc ggccatgtcg ccggcgaagg cggccgcgcg tgtccacgac
    12781 gtggtgctgc ccatgtcgat ccacgcacgg gcggtgcccg cgccgtcgtt catcgccagg
    12841 ttcaggagga gcagcaggat gctggtgctc atggggcggt cgatacgccc gaccatgccc
    12901 cagtcgatga gggtggcggg ctgcccgggg tggacgaaca cgttgcccgg gtgcggatct
    12961 ccgtggaaga tccggtcgac gaagtagccc cggtacatga aggcgagcag gtcctggccg
    13021 atcgccctgc gttcctccac cgtgaaggcg tcccggtcgg cgtcgcggac ggacgtaccc
    13081 ggcgccagcc cctggacgag cacccggccg gtcgcgtgga cgacgtcggg cacggcgatg
    13141 tggtcgaacc cggtggccgc ctcggcggcc tccgtcatgt tgcgggcctc cttgcggaag
    13201 tcgagctcgg ggcgcatggc gtcgaagacg acgcccagca tggcctcgac gtcgatgacg
    13261 tcgttgaacc gggtcgcgcg ccgtgccgcg aagcgcgcca gggtccggat gagtttcatg
    13321 tccgcgtgca ccgactcgcg cacaccgggc cgctggatct tcacggcgac gtggcggccg
    13381 cccggcagtt cggcccggta cacctgggcc agcgacgcgg tgcccagcgg gtggtcggtg
    13441 tcgatgtccg agaaccgctg gtgccacaac ggcccgagct cctccctcag caccggctcg
    13501 aacgcggcga acggagcggg ggagacgctg tcgtggagct tctcgaactc ggcgatcatc
    13561 tccgggggga cgaagtccgg gcgtgtggcg agcatctgtc cggccttgat gtagaacggc
    13621 cccaggctct ccagcgcctc acgggcgtgc cgcgcccggc gtgcgcccgc gttctcggcc
    13681 gacggcgcga aacggccccg gggcagcagg gtgtgggcag cctcggtccc ggcgagctgt
    13741 gccaggaccc tggccagcag acgcgcacgg tgctcggtca tcgccgtccc ctcgaagtcg
    13801 tgtcacccac ggcggcggtg gggccaccgc cacgggcccg ccgcgcgccc gcgcggctag
    13861 cgggcaacgt cggagagccg gtcgaggcgg gccgacagcg ccgccagatc cgcccggagc
    13921 gcgtcgacgt cctgggcgtc acgcggcggg ggaacgaccc cgggtgtccg catgcctctg
    13981 ccgtcgtccc ggtgctgttc caggcggtcc gccagcaggg agatccgctc cgtgagagcg
    14041 gacagtccct cctcctcacg tgagggggga ccggcgcggc ggacggtggt cgcccgggga
    14101 cggcggtcgg gaccgtcacg gtcgccgtcc cagttgccgt cccggtcccg gtgacggtcg
    14161 cgatcgcagc cgtcgtcccg gtccctgtcc cggccgcagt cgcggtcgcg atcccggtcg
    14221 cggtcccggc cccggtcgcg gtgccggtcg tcatgatcgc ggtggtcgtg gtcgtcgtgg
    14281 tccctgtcac ggcgacgcct gtcgtcgtcg agggcgtcgc tcagggaatg gcgcataccg
    14341 cgctcgaaat ccccggcgcg gtcgagggcg tcgtcgacca gatcctccgt cacatggacc
    14401 atgcgacgga gagcgtggct gagagaggtg cgggaatggc ggcgggacac agggggacct
    14461 ccaggggtga aaggacgggc accttgcggc gatcggtctg ccgttcgagg tgcccggggg
    14521 cgggcggccg tcagtgacgc ggttccgcgt cgtccacggg acgcaggtac acggccttgc
    14581 cgtaaccggt gtccagccag atcctgtgtt cccgggcgga gccggccagg ctcgggtgga
    14641 tgaagcgacg acggtaggaa gtgtccggat tcaccgtcac cgagacccac tccaggcacc
    14701 acgccggtcc gtcccccgcc gtctccaccc gcagatagac gggggagtgg gccaggtcct
    14761 ccgtactcaa cggtggcgta cggggatcgt tgtagtcgga atacttcaca ttgctctcct
    14821 cgccgaggag gaagcaggcg tccgcgcccc gggagaagtc cacatcatgt gtgtccagac
    14881 tgaactcccg tcctcccagg cccagataga tccacgatcc ggtcgaggcg tgctccacgt
    14941 ccgcggtcac gatgtgcgcg atgatctgcg agatggcggc catggggact ccttcccagc
    15001 cggaccggaa ggcccgtctg catatatggg cgatctgaat gcgctgtgcc gaatgccgtc
    15061 cgggaggcgg agccgcaccc gctcgtcatg ccgcacggct ccgctgccgg ccggggcggg
    15121 ggcgcgcacg gcatggcccg cagggggtgc gtgcgtcgcg tcgagtgctg gtgtcggtac
    15181 cagcatcccc ccttgttgtg actctatgca cccacgtgag cacttacagt tgccatgagg
    15241 ggtgcgccgg cgcacaccgt cgagccgggg cgcacaacag cacctcacgg gccgcccgcg
    15301 cgcaccctgt ccctggagcg gatccgccaa ctcggcaagg agagcgcgcc cttcggacac
    15361 cggtcaccgg tcacccgaaa gcaaagggcg agaaggcgag ggggtgacac aaccgcggcg
    15421 tgtgacggac cttttggcgg taccgtcgga ctgccgggct ccggtccggt cgaggcggac
    15481 ccgtccggac cgcctcgacc gggcgccccg ggctgagcgc cgtgccaggc ccccggagca
    15541 tctcgcggac cgggcccggt ggtggtttct ccccgcgggc cgacgcgccg gggctgctca
    15601 ccactgcccg gattccttcc ggccggccgc acgggctgct ctcgcgcatg agatgccgag
    15661 cgatcctcag ggccgttccg cggcagtccc cagggccttc tgcgacaggg gaggacggga
    15721 acacacccgg ccgggacctc ccgcgaaccg cggacacggc tcaacgccca cggtcctcgc
    15781 aacccccgca gatcgcgggt gttgcgagga ccgtcagaac ccgagccggg gcagccggac
    15841 cctggaccgt tcgctaccgg gccccggtac gcaggccgcc gtgacggccc gccatgatca
    15901 cttgctgacg gcgaaacgca tcagcgcctg ctcgttgccc tgcttgatct tgcccgtcac
    15961 gttgatgacc tccagcttcc aggcgctccc cacccggaac gccttcgcca cggcgcacgc
    16021 gttgtcggcg gacagcaggc tcggccagat gtcggcgacc tgctgcgagc tgcccccggt
    16081 ggcgtcgtac accttgaagc tgatgttgcg cgccttctgg aaagagctgc ccttcttgta
    16141 ggcggcggcg acgaatacga acgacgtgat gttctcgggg accttcgcga agtcgaccgt
    16201 cacggtctcg tcgtcaccgt ctccccggcc ggtctggttg tcgccgctgt gcagcagaga
    16261 accgttgccc agcgggtcga gcgagtcgag gcccgccagg cgcaccgggt cggcaccctg
    16321 catggcgatg gcgatcaggt cgagatcggt gccggtcttg cggcggagca ctcccatcac
    16381 cccgccggaa ctgccggagg tggggtccca ggacacaccg atcgacagat gggtcactcc
    16441 gtcgaggtcc gccgggccgt cttccttctt gagcgtgatc atgcgcaggt cttccttcaa
    16501 aacgatgatg cgacacagtg agtgtgcctg gagtgggctc gtacgcgtgc acccggtatg
    16561 ccccgatgcc gttccggcac ggaccggacc cggtggccgc cgtccgcgcc gcccgtggtg
    16621 ttccgcccgg acggccttga gcggtgggcc ggttgacggg ccgcgaggcc ccggcacggg
    16681 ctcggcgccg tccgcgggaa gcgggaagca gtaccgcggg gcggcccccg catcgtgcgg
    16741 ccctcccgcg caaaggaccg ggcacggatg accgtggaga tggcggcgcg gctcaccctc
    16801 ggtcatccgc gcagtctacg cgcgccctcc cagcgggacc gaggggttcc ggagacggaa
    16861 tcccggtgtc ccgtccgccc ctccccaccc gccggcccgc catccgtcac tgtgcggtga
    16921 tgcgcaggac cccggtcacc gtgccctgga ggtaggcgcc gtcccgggtg atcgtgcccg
    16981 ccatctgcag gctgtcgtag agcgaaccca ccccggtcct caccgagcgg acgacctgtc
    17041 cgctgtccgg gtcgatctgc gcatagcggt acgggtcgag cagactcgtg ccctcggtcc
    17101 cagggatcag cgggtcacgc accacggtgt ggagcagccc gtcggccgtc gacagcttcg
    17161 gtacggcggc cgaccgcacc gtgttgtccc atacgaggtc gcagcccgta ccgcccggcc
    17221 gtacgtccac ccgggacagg ccgcccgtga agccggcgga cgcgggcacg gccggacccg
    17281 ccccctcggg cacagcgggg tacggatagc cgtacgtacc cgccacgaag acgctgcgcc
    17341 cggcgcccac cggagagttc tcactggcgg gaccgtccgc cgcccggagc accggcacgg
    17401 agcagacgtc cgaaccgtcc cccgtgcggt agaccttcag gttcgcggcc gtgtcggcgt
    17461 tgtcgacgat cgtcacgtac tccgtcccgg tgcccggccc gaagaacgtg ggggtcgatc
    17521 cgctgcccca gctcagcagg cccggcttgc gggcggagcc ccggtcgtat tccttgcgcc
    17581 agacggtcct cggggcaccg gtgccgtccg cggtcagcag ataggtggca tgggtggtgg
    17641 tgaccgcggt gccctcgggg gccgtggaga tgctgttggc gacccgctca cccgcgggca
    17701 gggacagggc ccggacggtg ccagtggcgt cgtccgccgt gccgacgatc ccgccgccgg
    17761 tggcgaacca cacccggccc gaccagtccg gcgccagccc ggtcaccgcg tcgccctcgg
    17821 gtatgacgga ggccagcgac aggcgccggt cgacggtcag ccgccagtct cccgcggcgt
    17881 cccggtgatg gccgacgcgc agcaggctgc ggctcccgtc cgcgacgacc agccggtcca
    17941 ggtgatcgat gtaggcgtac acaccgccca gcagcgaccc cttggtcagt tgcagcgagg
    18001 ccagggagga gccgtctccc ggatccagca gatggaccgt cggcacctgg ccgaagatcg
    18061 gtgtgcacag ggccaccgga taaccgtcga agccggccag cacggtgggg cacgccgaag
    18121 cgagcgcggt gcgtgaggac ttcagggtcc ccgcgccggg cccggccagt ggtgtggtgt
    18181 ccgaggaccc ggtgtccccg tgcatggtgg cggtgccgtc gggccccgcg taggggttgt
    18241 ggggcggcgt cggaccgaag gaggcggcgg aaccggccgg ggccggggag acggccgagg
    18301 caggagtggc gaagccgagg aggaacgctg ccagcagggc accggccgcc tggcggcggg
    18361 cggtcctgcg ggagccgggg gagtgggaca cggcgggacg ggtcctttcg gagaaggatg
    18421 aagaagggag gaagaaggga gaacgggagg aggagggaaa ggggagggga acggcgcggt
    18481 gcggacgtac ggaccggatg cctccgctcc cgcccggtga cggcagcgga ggcacacagc
    18541 gcggagaaca ccgacggacg cggacagcac ggagaacgcc ggacggacgc gggcagcgcg
    18601 aaggaaccgg acggacgagc gggagcgagc cgtccgcgga cggcacccgc cggcaccaga
    18661 accccgccgg gacgggatca caggtgacgg agcatcagcc ggtgcttcag ggccgggcgc
    18721 cggcgaaccg ccggacgcgg gcccgtgcgg agccggggga gagggaagga gacgccctca
    18781 ccgcccgcgg gccgtcagcg gccgcggaga cagagcgcgc cggcggtacg cgcgagatcg
    18841 acatggcgtc gtcgcgtgag acccgggcag cacttcatgc gggtgatcca agcagcaccg
    18901 gcggcacccg gtcaagagcc cgccgcttcc aaccgggaag acacccgtcg ccgccccggt
    18961 gcacctcggc cgtcccaccc ctccccgggc cggacgaggg catctcccgg cagacccggg
    19021 aggattcggg gttgccggga caccccgcac accctgcggg cagcggtccg tgaccggctg
    19081 gtggagcgga ggatgccgct ccaccagctc caccaggcgg cggacgccct cgggttcgtc
    19141 accactgcgg accagccccc actacggata cgggaccggc tccccgcgct ccgccgcgaa
    19201 gtcgaagcgg aacgcccggc cgggcaccgc gcgcctcgcg gtggcgatgc gccaccggta
    19261 cgccctccac gcccaccgga ccaggaccgc accggtgggc gtaggtgatg ccgttcatcc
    19321 cccaccccag ggcgatcacc gtgtccggga gccccggcag gaccagacgt tcggccggca
    19381 cacggaagtg ctcatccgac tccccgtcca actcccagtc cgagcccgcc cgaagcagcg
    19441 tccgcactta cccgtccgga aggcgcccct cgctccgctc cggcatcggg gtgcccggca
    19501 cggacatccg gtcccggcgg ccttgcgcca ggccgcccac gcaccgggga acccggggcg
    19561 cccctcgatg ctgtcccaca ggccgccggg cagacgcctg cgcccggccc gcagccgggt
    19621 cccgccgagc tcgaacggca aacgggtggc ggctgaacgc atgaaatccg cagggcgctc
    19681 cgcgtgcgtc tcgtccacca gccggcgggc ggtggcggcg ataccctccc cggccgccgc
    19741 gagcaggcgc ggggcgaacg cacgcgagac ggtcctgcgc agaccggcgt gctcgccgcc
    19801 gtccatgcgc accgtggaac tgccggacac gaccccggcc cagcacgcag gctccggggt
    19861 ggtgaccccc ggagcgctcc cgaagacctg cggcagacgg ctcgccgcct tcacgtcccg
    19921 tgcctcacca gggcgtggaa aggcggctgc gatcccgtgc ggggcatgga ccggaccggt
    19981 gcgaccagct gccggagacg cgcgaacgcg gcgagccgct ttgcccgcgg cagccgccgg
    20041 aacgaggggc cggccagatc ggcgtgcccg tccggaccgt cgcggcccgc gggcccggtg
    20101 ccgtcccccc ggccggcgga tccggcaccc cggacctcgt ccccggtcac ccgcgacggc
    20161 gtgttcatgc acagcctccg gacgtacgga ccgccatgct ggtcccggac ggaccgccgg
    20221 cacggccgtg ccggtccgcg gattcccacg gccgtgtgac gtacaccggg aagagaaccg
    20281 ttcgcccgcc ctctcgttgc ccacacgaga gcgatcactt gcgcgagagc gatcacccac
    20341 acgagagcgg acgagagaca gggacaccac tcatggaccc gaccaccccc acgaccaccg
    20401 ccggccccgc cggtacgccc ccctccgcac gccggccggg ccgccgtgcc gcactgcgca
    20461 ccgtcttcac cgcggccgcc gtcgccggaa cggcgggcgc gctggctccc gtcctgttca
    20521 aggggaccgg aaccccgccc ggcggggacc ggcgccagca ggcacccgaa cggttctcgg
    20581 agcgctaccg gggccgcgag atcaaaggca ccctcacggc cgtggtcccg gccggcggcc
    20641 cggcgcggcc ggacacggcg gcggcagccc tcgccatgga cgccgccgac gtgacgatcg
    20701 acggacggcc gctgcacctg atgcggcgcg ccgacgggag ctacctcagc gcggtcaacc
    20761 actacgagtc gttcccgacg ccgctcgaag cggcccgtgc cgcggtcgac gaactcggtg
    20821 aagcccggct gtccgccacc tccccgcaca ccatctgagc ccctcatctg agccgaagga
    20881 cgagcacggg tgtacagccg caagaaccaa cgcgacctca cacgcacgga gaagaagcgc
    20941 ctggtcacag ccatcctgga actcaagcgc accggacggt acgacgaatt cgtcaccatg
    21001 caccgggagt tctacgtcac cgacgccgac aggcggcccc gggccgccca tatgaccccg
    21061 tccttcttcc cctggcaccg cagatacctg ctggagttcg agaaggccct ccaggaggtc
    21121 gactccgggg tgtcggtccc gtactgggac tggacccggg acaacacccc ggccgcttcc
    21181 ctgtgggcgg aggacttcct cggcgggaac ggcagacggg gggaccggca ggtcatgacc
    21241 ggggcgttcg cgtaccgcga ggggaactgg agcatcaggg ccgcgatcac cgacgacccc
    21301 ttcctgcggc gcgacttcgg ccgcccctcc gcccccgtga ccctgccctc cgcggccgac
    21361 gtcgaccgcg ccctggccga ccccgtctac gacaccgacc cctggaacag cgtcaccccc
    21421 accggcttcc gcaaccggat cgagggctgg ggcatccggg gtgtccgggg cgtgaccaac
    21481 cacaaccggg tccaccgctg ggtgggcggc tccatggcgg gcgccgcttc gcccgacgac
    21541 ccggtcttct ggctgcacca cgcgtacgtg gacctgctct gggaccgctg gcagcgggcg
    21601 catcccggct ccggatacct gccggcccgt ccgcccgccg ccggggaccc gcagcgaggc
    21661 cgtgtcttcg cccttgacga ccccatgccc ccctgggacg tgaaaccctc ccaactcctc
    21721 gaccacagcg gcctctaccg gtacgtctga ggaccggagc caggaccgtg gccggccggg
    21781 aacgggccgg gccccccttc ccgccgcaac gggaagaggg gcccgggacc atccggtacg
    21841 gactcagtag ccgtagccgt aatcgccctc gtggtgggag tcgctgcccg acacgttcgc
    21901 gcaggcgtta ccgaaagccg ggttcagcag ggcgatgacg tcgacggtgt tgccgcagac
    21961 gttgatcggc acgtgcaccg gcacctggac ggcgttgccc gacaggacgc cgggggagtg
    22021 ggcggcaagg gcctcggccc cggcgtcggc ggacgcgaaa ccggcgccgc cgacgatgag
    22081 ggcccccgta cccgccacga cagcggctgc cttcgagatg cgcgacatca gtgttctcct
    22141 tgaaaggtcg aaagccgggc gcagaacgtg caccggcatg cactgacaac gcgggaatcg
    22201 acagacggta acggatcaga tcaaaagtcg taaccgggat ctccctcagc cccggcccct
    22261 ccctctccgt ccgcgtactc gccgcctccg cgtcaccgcc cgcgcgtacc gttccggcga
    22321 gggcgggcgc gcgggcaggg gggtgacgcg ggaccatcgg acggctcccg gccgggcacg
    22381 cccgtacctg tgacgccgtg cgtaccccgc ggtgcagcat gacggcggtg ccgtgcaccc
    22441 cgcgccgcgg ctcggcggcc gtgccgggac ggccgggcga cgccgggcga aacgcccgcg
    22501 ggcaccgggg agtcgcacgg ggccggtgcc ctgtcccgcc cggctgccgg acggcgcgcg
    22561 gcccccggcc cccgaggccc ggtccggaac cggccgactc cggggaaacc gccggactcc
    22621 gggccgcgtc acgtgtgtac tgcgggaggc ggtcccgctg cctgtgcggt cggagggccc
    22681 ccatcgggta caactcgtga tgaccgtcag ccccgtggcg gtccgcggag ccggaccggc
    22741 cgacgacgac acaaggagaa gcgatggttc acgaacgggc cggacagccg gcacagcccg
    22801 gagacctggt ggacgtggcg cgtctggtga cggcctacta ctccgtccgc cccgacccgg
    22861 ccgacccggc ccagcgggtc gccttcggca cctccgggca ccgcggctcc gccctcgccg
    22921 cggccttcaa cgaggaccac atcgccgcca ccacccaggc catctgcgat taccgcagcc
    22981 ggcagggcac cgacgggccc ctcttcctcg gcgccgacac ccacgcgctg tccgagcccg
    23041 cccgggtcac cgcgctggag gtgctcgccg ccaacggggc caccgtcctc atcgactccg
    23101 gcgacggata cacccccacc ccggccgtct cgcacgcgat cctgacccac aacagggacc
    23161 gcgaacagca cctcgccgac ggcatcgtgg tcacgccctc ccacaacccg cccgccgacg
    23221 gcggcttcaa gtacaacccc ccgcacggcg gcccggccgg ctcggacgcc acctcctgga
    23281 tccaggaccg cgccaacgcc ctgatcgagg gcggcctcaa ggaggtccgc cgcatcccct
    23341 tcgcccgggc cctggccgcg gacaccaccg ggcggtacga cttcctcacc gcctacgtcg
    23401 acgacctccc cgccgtcctc gacctggacg ccgtgcgcga cgcgggaatc aggatcggag
    23461 cggacccgct cggcggcgcg tccgtcgcct actggggccg gatcgccgaa cgccaccgcc
    23521 tcgacctgac ggtggtcaac ccgctcgccg acccgacctg gcgtttcatg acgctggact
    23581 gggacgggaa gatccggatg gactgctcct cgccgtacgc catggcctcg ctgatcgagc
    23641 agcgcgacgc ctacacgctc gccaccggca acgacgccga cgcggaccgg cacggcatcg
    23701 tcacccccga cggcgggctg atgaacccca accactacct ggccgtcgcg atccgctacc
    23761 tctgctccca ccgtgccgac tggccggccg gcgccgggat cggcaagacc ctggtctcct
    23821 cgtccatgat cgaccgggtc gccgcggacc tcggccgccc cctggtcgaa gtccccgtcg
    23881 ggttcaagtg gttcgtcgac gggctcttcg gcggcaccct gggcttcggc ggcgaggaat
    23941 ccgccggggc ctccttcctg cgccgcgacg gccgggtgtg gaccaccgaa aaggacggca
    24001 tcctcctcgc cctgctggcc tcggagatca ccgccgtcac cggctccacg ccctcccagc
    24061 actaccgtga actcaccgac cgcttcggcg accccgccta cgcccgcgtg gacgcacccg
    24121 ccacccgcga ggagaaggcg gtgctggccg cgctctcccc cgaacaggtc accgccggga
    24181 ccctggccgg cgagcccgtc accgcggtgc tcaccgcggc ccccggcaac ggcgcggcca
    24241 tcggcggcct caaggtctgc accgacagcg cctggttcgc ggcccgcccc tccggcaccg
    24301 aggacgtgta caaggtgtac gcggagagct tccagggccc cggacatctg tcggaggtcc
    24361 aggacgaggc ccgcgccctg gtctccgacg cactgggcag gagctcctga cggaagggga
    24421 gtccggcccg gtgccgcgcg tccacacctc gggcgacggg cactgggccg ggcccgtcgc
    24481 ccgaggcggc gccgcgaccg tcctccaccg gaccgccggc cggcggagga cggagggcgg
    24541 ccgcggcagc ggaagcaccg gcgccccggg aagaaggcgg atacaggtgt cgccgtgaaa
    24601 caccacgccc cccggacacg gaaaaggaac ggttcccgga caagcgcgat cagccgaacg
    24661 ggggatggag ggaaatattt gtccgcgccg ccaatttccc tggtatgtca tcccctgccc
    24721 gacgttatgc tgccgccgat ccagcaccgc caccgaaggg acgcgccgtg cccgtgggac
    24781 ccgtggaata cctcgtcgtc acctttccgg gcagccggtt cgccgacgcg atcgcacccg
    24841 tcctggcgga cgcggtcagc tccgaggccg tacggatcct ggacctgacg ttcgcccgta
    24901 cggcccagga cggcgcgctg gagcacgtcg ggctgagcga gctcgacccc gaaggggcgg
    24961 tcgccttcga gaagcccgcc gacagcgggg tgagggcgcc cgacctcacc cgcaccggcg
    25021 ccctggccgg cctgccggcc gggagctgtg ccgcgctgat cctctgggag gacctctggt
    25081 ccgtgcccct gacccacgcc gtacgggcgg cgggcgggcg gctcgtcgcc cacgaacgcg
    25141 tcccggtgga cggcgaggac gacgtcatca ccctcctcga acggctcgcc gcactccgcg
    25201 agaagggcga actcaccgac gccgagttcg cggcgcagaa gaccaggatc ctcgccgact
    25261 gaccaccggg ccgcggcggg cttccttttg tcgattccgg cgggccgtgc gacgttgttc
    25321 ctgacctgtg caggccgtcg ggaaagaggc agttcatcgt gcagaccgcc cgggccgtgc
    25381 cggcctccac cgtcgtcaat ctgcgcgatc tgggcggcat cgccctgggg cgtgaccgcc
    25441 gtctgcggca ggggatcctg ctgcgctcgg ggcagttgag cgacttcgac gcggaacacg
    25501 acatcgcggt ggccgcgctc ggcatccgta ccgtcgtcga cctgcgcacc gccgacgaac
    25561 ggcagtgggc cccggacaga ctgccgcccg gcgcacggct cttcgtcgcc gatgtgctcg
    25621 gcgaccaccc cggagtgacc cagggcagac tccgggcgct gctcagcgac ccggcggcgg
    25681 ctttcgacgc gctcggcggc ggcaaggcgg aagggctgtt cgcccaggtc taccgcaaga
    25741 tggtcctggc cccgggggcg gccgcggcct accgggcctt cctggagacg gcggccgacc
    25801 ccggggccag gcccctgctc ttccactgcg cgaccggcaa ggaccgcacg ggatgggc
//
