LOCUS       NZ_CP023702            21053 bp    DNA     linear   CON 23-APR-2024
DEFINITION  Streptomyces nitrosporeus strain ATCC 12769 chromosome, complete
            genome.
ACCESSION   NZ_CP023702
VERSION     NZ_CP023702.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nitrosporeus
  ORGANISM  Streptomyces nitrosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7581562)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008704555.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:20:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,704
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,461
            CDSs (with protein)               :: 6,461
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 66 of 146
            Pseudo Genes (incomplete)         :: 106 of 146
            Pseudo Genes (internal stop)      :: 16 of 146
            Pseudo Genes (multiple problems)  :: 38 of 146
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6545198
            Orig. end                         :: 6566251
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023702.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..21053
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="24"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21053
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21053
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11053](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11053)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(666..681)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.18"
                     /tool="antismash"
     misc_feature    complement(680..695)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.47"
                     /tool="antismash"
     misc_feature    682..698
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.74"
                     /tool="antismash"
     gene            856..2064
                     /gene="metK"
                     /locus_tag="CP967_RS29005"
                     /old_locus_tag="CP967_29080"
     CDS             856..2064
                     /EC_number="2.5.1.6"
                     /GO_function="GO:0004478 - methionine adenosyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006556 - S-adenosylmethionine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /gene="metK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009187586.1"
                     /locus_tag="CP967_RS29005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29080"
                     /product="methionine adenosyltransferase"
                     /protein_id="WP_150492102.1"
                     /transl_table=11
                     /translation="MSRRLFTSESVTEGHPDKIADQISDTVLDALLREDPSSRVAVETL
                     ITTGLVHVAGEVTTKAYADIPTLVRNKVLEIGYDSSKKGFDGASCGVSVSIGAQSPDIA
                     QGVDTAYEKRVEGDEDELDKQGAGDQGLMFGYACDETPELMPLPIHLAHRLSRRLSEVR
                     KNGTIPYLRPDGKTQVTIEYDGDKAVRLDTVVVSSQHASDIDLDSLLAPDIREFVVEHV
                     LGQLVGDGIKLDTEGYRLLVNPTGRFEIGGPMGDAGLTGRKIIIDTYGGYARHGGGAFS
                     GKDPSKVDRSAAYAMRWVAKNVVAAGLAARCEVQVAYAIGKAEPVGLFVETFGTATVDT
                     ERIEHAIGEVFDLRPAAIIRDLDLLRPIYAQTAAYGHFGRELPDFTWERTDRIDALREA
                     AGL"
     gene            2197..4341
                     /locus_tag="CP967_RS29010"
                     /old_locus_tag="CP967_29085"
     CDS             2197..4341
                     /EC_number="3.6.1.-"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003678 - DNA helicase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006260 - DNA replication [Evidence IEA]"
                     /GO_process="GO:0032508 - DNA duplex unwinding [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044799.1"
                     /locus_tag="CP967_RS29010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29085"
                     /product="primosomal protein N'"
                     /protein_id="WP_150490801.1"
                     /transl_table=11
                     /translation="MSSDDERSDEPGTGQPEQLALIRETVRRAEVPRAKPRTWRGAALA
                     GKLPVARVLVNKGVLHLDQYFDYAVPEELDADAQPGVRVRVRFGAGGRQVRGGRREGGG
                     LIDGFLVERRATSDYPGALAALAYVVSPEPVLGPELLALSRAVADRYAGSLADVLQLAV
                     PPRNGRAESRPSPAPPPPPPVPSPGPWERYAQGPGFLRALAGGEAPRAVWTALPGPHWP
                     EEIARAVAATLASGRGALVVVPDGRTAGRVDAALTALLGKGHHALLTAESGPEKRYGQW
                     LAVRRGSVRAVVGTRAAMFAPVTGLGLVAVWDDGDSSHSDDNAPFPHVREVLELRAAHS
                     RCAFLLGGVNCTVEAAQLVESGWALPLRPDREQVRIAAPLVRTVDDGELARDGAARSAR
                     LPSLAWQTVRDGLRDGPVLVQVPRRGYAPRLACERCREPARCRHCAGPLQAPDRQNLEC
                     AWCGRTETAWNCAACGGTGLRAQIVGARRTAEELGRAFPDVPVRTSGRDHVLDSVPGQP
                     ALVVSTPGAEPVAEGGYTAALLLDGWAMVGRPDLRAGEEALRRWTAAAALVRGRPEGGT
                     VVVVAEPALRPVQALVRWDPVGHARRELAERAELGFPPVSRMAAVTGPPEALAAFLATA
                     ELPAEAEILGPVPVPAAPTGRPRRPGDAPPGAPRERALVRVPPGRGAALAAALKAASAA
                     RTARGSGDPVRIRIDPPDIG"
     gene            complement(4478..5023)
                     /locus_tag="CP967_RS29015"
                     /old_locus_tag="CP967_29090"
     CDS             complement(4478..5023)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057355.1"
                     /locus_tag="CP967_RS29015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29090"
                     /product="hypothetical protein"
                     /protein_id="WP_150490802.1"
                     /transl_table=11
                     /translation="MADHATHDAQARASLHLLVRDIERVRRQVDALRTLTAQLGNVYRP
                     RRSGPSAGFVVYGRAPAPTVRLAQELRDSVETLVTAAVDFDRSLGFSWDAVGSALGVTK
                     QAVHRRYGTRRSAPQPPAAEAEGAAPRKASAAAGPGQPLPVVPSARPMPPQPPPPSPDG
                     AVSREELRPGAFPGPRNG"
     gene            5337..6269
                     /gene="fmt"
                     /locus_tag="CP967_RS29020"
                     /old_locus_tag="CP967_29095"
     CDS             5337..6269
                     /EC_number="2.1.2.9"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0004479 - methionyl-tRNA formyltransferase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006431 - methionyl-tRNA aminoacylation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fmt"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1228: methionyl-tRNA formyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490197.1"
                     /locus_tag="CP967_RS29020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29095"
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="WP_150490803.1"
                     /transl_table=11
                     /translation="MKLVFAGTPEVAVPALDALIASGRHEVAAVVTRPDAPAGRGRRLV
                     ASPVAERAEEAGIEVLKPARPRDEDFLARLREIGPDCCPVVAYGALLPGAALEIPAHGW
                     VNLHFSLLPAWRGAAPVQHAVMAGDEVTGASTFLIEKGLDSGPVYGVLTEEVRPTDTSG
                     DLLTRLAFAGAGLLAATMDGIEDGTLHAVPQPAEGVTLAPKITVEDAQVHWQAPALRVD
                     RVVRGCTPAPGAWTLFRGERLKLVQAVPVPGRTDLTPGELSAGKNNVYVGTGSHAVELL
                     WVQPQGKKPMKAADWARGVRITSGELLGA"
     gene            6394..7827
                     /locus_tag="CP967_RS29025"
                     /old_locus_tag="CP967_29100"
     CDS             6394..7827
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018551353.1"
                     /locus_tag="CP967_RS29025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29100"
                     /product="transcription antitermination factor NusB"
                     /protein_id="WP_150490804.1"
                     /transl_table=11
                     /translation="MNDQQRRRPAKQHRRPKKDPVRFLAFEALRAVDERDAYANLVLPP
                     LLKKARAKGDFDSRDAALATELVYGTLRRQGTYDAIVAACVDRPLREVDPPVLDVIEMG
                     VHQLLGTRIPTHAAVSASVELARVVLGEGRAKFVNAVLRRVTAHDLDGWTERVAPPYDE
                     DPEEHLALVHSHPRWVVSALWDALGGGRSGIEDLLEADNERPEVTLVARPGRSTPEELL
                     TALGEERGLPGRWSPYAVRMAEGGEPGALAAVREGGAGVQDEGSQLVAAALAHAPLEGD
                     DTRWLDGCAGPGGKAALLGALAAERGAALLASEKQPHRARLVERALAGNPGPYQVITAD
                     GTRPPWRPGSFDRVLMDVPCSGLGALRRRPEARWRRRPEDLEGFAPLQRGLLREALKAV
                     RVGGVVGYATCSPHLAETRVVVEDVLKGRGGQPAEAEWVDARPLFPGVPALGDGPDVQL
                     WPHLHGTDAMYLALLRRTA"
     misc_feature    8082..8095
                     /note="TFBS match to ANR, Anaerobic transcriptional
                     regulator, confidence: weak, score: 19.21"
                     /tool="antismash"
     gene            8082..8765
                     /gene="rpe"
                     /locus_tag="CP967_RS29030"
                     /old_locus_tag="CP967_29105"
     CDS             8082..8765
                     /EC_number="5.1.3.1"
                     /GO_function="GO:0004750 - D-ribulose-phosphate 3-epimerase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="rpe"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044795.1"
                     /locus_tag="CP967_RS29030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29105"
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="WP_150490805.1"
                     /transl_table=11
                     /translation="MAQINPSILSADFARLAEEAKAVDGADWLHVDVMDNHFVPNLTLG
                     VPVVEALSKATDTPLDCHLMIEDADRWAPQYVEAGAGSVTFHVEAAAAPVRLAREIRAK
                     GARASMALRPATPIEPYEDLLPELDMLLIMTVEPGFGGQAFLDIMLPKIRRTRELISKH
                     GLELWLQVDGGVSATTIERCAEAGADVFVAGSAVYGAEDPAEAVRALRARAEAATAGAP
                     WACGH"
     gene            8896..9888
                     /locus_tag="CP967_RS29035"
                     /old_locus_tag="CP967_29110"
     CDS             8896..9888
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014044794.1"
                     /locus_tag="CP967_RS29035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29110"
                     /product="sugar-binding domain-containing protein"
                     /protein_id="WP_190175388.1"
                     /transl_table=11
                     /translation="MRMGPAELVQAAAMARRFYLEGKSKIQIAEEFGVSRFKVARVLET
                     ALERDLVRIEIRVPAELDAERSDALRARYGLRHAVVVESPAEEQDDAADPENLGEVAAD
                     LLGELVNEGDVLGLAWGRSTIHMAAALDRLPPCTVVQLTGVYDAGTAERGSVEAVRRAA
                     QVSGGEAHPIYAPMLLPDPATAAALRHQTGIARAFEHFDKVTVAAVSIGSWEPGISTVH
                     DMLSDDERAHYASLGVAAEMSAHLFDADGRRVGRDLGERCITVEADRLRRIPEVVAIAG
                     GQRKAAAIGAVLRSGLVTSLVTDTAAADYLLTESAAGPRPALERADPDD"
     gene            complement(10001..11053)
                     /locus_tag="CP967_RS29040"
                     /old_locus_tag="CP967_29115"
     CDS             complement(10001..11053)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018490193.1"
                     /locus_tag="CP967_RS29040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29115"
                     /product="terpene cyclase"
                     /protein_id="WP_150490807.1"
                     /sec_met_domain="T1TS (E-value: 2.8e-86, bitscore: 289.2,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MESELPDIYCPFPQRSNPHVAHTRAHLDEWTRRTGLVHRESARAR
                     FEQADFGSFVGMVHPTASPEHLDLVADWFVWLFLVDDQLDDGHLGRNPERVRDVVARMR
                     AVVEGTAPRVPPGEEAPAALVALADLWERTVPRAAPHWRTRFTGHLMTYLTMTTTWEAG
                     NRATGAVPSEAAYISKRRHTGAIHVCMDLIEIVAGIQAPEAVHGDPRFVTALEASCNVV
                     CWANDVYSYEKEQMLGEIHNLVHLVRHHRGYGERQALEHVCAAIATETERFLTAEDELL
                     EVFPQLTRTLVPYLDGMRSWMRGNLDWSRQTPRYNPAAVSQYAAPGEYLEETVLGVATD
                     GAVAAPRTGD"
     gene            11455..12921
                     /locus_tag="CP967_RS29045"
                     /old_locus_tag="CP967_29120"
     CDS             11455..12921
                     /GO_function="GO:0003938 - IMP dehydrogenase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103924.1"
                     /locus_tag="CP967_RS29045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29120"
                     /product="GuaB1 family IMP dehydrogenase-related protein"
                     /protein_id="WP_150490808.1"
                     /transl_table=11
                     /translation="MRFLEPGTGRYTATPSVPYDLTYDDVFMVPGRSSVGSRQAVDLSS
                     PDGTGTTIPLVVANMTAIAGRRMAETVARRGGLVVIPQDIPLDVVTEVIGWVKKRHLVL
                     DTPIVLAPGQTVADALSLLHKRAHGAGVVVDAEHRPVGVVTDHDLAGVDRFTQLSEVMS
                     KDLVVLDAGIDPRDAFNRLDGANRKLAPAVDADGRLVGILTRKAALRATLYTPATDADG
                     KLRVAAAVGINGDVAGKAEQLLAAGVDTLVVDTAHGHQESMISAVAAVRKLDPGVPVVA
                     GNVVAAEGVRDLIEAGADIIKVGVGPGAMCTTRMMTGVGRPQFSAVLECAAEARKHGKH
                     VWADGGVRHPRDVAMALAAGASNVMIGSWFAGTYESPGDLQQAADGRFYKESFGMASAR
                     AVRNRTSEESAYDRARKGLFEEGISTSRMFLDPARPGVEDLIDSIIAGVRSSCTYAGAA
                     SLEEFAEKAVVGVQSAAGYAEGKPLHASWS"
     misc_feature    complement(13059..13073)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 26.66"
                     /tool="antismash"
     misc_feature    13086..13099
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.15"
                     /tool="antismash"
     misc_feature    13087..13100
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.76"
                     /tool="antismash"
     misc_feature    13088..13101
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.06"
                     /tool="antismash"
     misc_feature    complement(13089..13102)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.46"
                     /tool="antismash"
     misc_feature    complement(13090..13103)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.26"
                     /tool="antismash"
     misc_feature    13091..13104
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 18.48"
                     /tool="antismash"
     gene            13147..14607
                     /locus_tag="CP967_RS29050"
                     /old_locus_tag="CP967_29125"
     CDS             13147..14607
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017: aldehyde dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576365.1"
                     /locus_tag="CP967_RS29050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29125"
                     /product="aldehyde dehydrogenase family protein"
                     /protein_id="WP_150490809.1"
                     /sec_met_domain="Aldedh (E-value: 4.6e-157, bitscore:
                     521.8, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAFFTDLALQYIDGEWRPGKGAWDIIDFNPYDGEKLASITVATA
                     DEVDQAYRAAERAQEGWGRTNPYIRRAVMEKALRVVEEREAEIAEAIVAELGGTHVKAG
                     FELHLAKEFLRESVQLALRTTGQILPSPTEGKENRVYREPVGVVGVISPFNFPFLLSLK
                     SVAPALALGNAVVLKPHQNTPVCGGTLVAKVFEEAGLPAGLLNVVVTDIAEIGDALLEH
                     PVPRLISFTGSDKVGRHVATVCASHLKQTVLELGGNSALIVLDDADIDYAVDAAVFSRY
                     VHQGQVCMAANRILVDRAVADEFTEKFVAKVASLRIGDPADPATHIGPLINSSQAEAVS
                     KLVDRTVGEGATALLHGTADGNLVSPSVLTDIAAGSPVLQEEIFGPVALLIPFDGEDEA
                     VRIANDTPYGLSGAVHTADVERGVRVGRRIRTGMIHINDGTVHDEPIVPFGGEKNSGLG
                     RLNGDATVDAFTTRKWISVQHGRSRFPF"
     gene            14724..15179
                     /locus_tag="CP967_RS29055"
                     /old_locus_tag="CP967_29130"
     CDS             14724..15179
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1120: AsnC family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018512479.1"
                     /locus_tag="CP967_RS29055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29130"
                     /product="Lrp/AsnC family transcriptional regulator"
                     /protein_id="WP_150490810.1"
                     /transl_table=11
                     /translation="MRLNDLDERIVHALAEDARRSYADIGAVVGLSAPAVKRRVDRLRA
                     EGAITGFTVRVDPGALGWETEGFIEIYCSRNTAPEAIRQGLARFPEVASASTVTGEADA
                     VVQVFAADMRHFEQVLERIAGEPYIERTKSVLVLSPLLRRYSQGPPA"
     misc_feature    complement(14743..14757)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.1"
                     /tool="antismash"
     gene            15531..16328
                     /locus_tag="CP967_RS29060"
                     /old_locus_tag="CP967_29135"
     CDS             15531..16328
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1294: Nitrilase/cyanide hydratase and apolipoprotein"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018103926.1"
                     /locus_tag="CP967_RS29060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29135"
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="WP_150490811.1"
                     /transl_table=11
                     /translation="MPLLRTALLQSSGRPGLVGHNLALLDEAAGRAAAAGARLLVSPEL
                     FLTGYAVDDALPGLAEPADGPGAEAVSAICVRHGIAVAYGYPERSGGRLFNAVQLLGPD
                     GTALAGYRKTHLYGSFEQRWFTPGDRTVVQAALDGVRIGLLICYDVEFPENVRAHALAG
                     TDLLLVPTALMRPFGFVAESVVPVRAFENQLYVAYVNRAGPEGTFDFTGLSCLAGPDGT
                     ARARAGQGEELLLADADPARLAASREANTYLRDRRPALYGSLL"
     gene            16382..18073
                     /locus_tag="CP967_RS29065"
                     /old_locus_tag="CP967_29140"
     CDS             16382..18073
                     /EC_number="1.-.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014671499.1"
                     /locus_tag="CP967_RS29065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29140"
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_150490812.1"
                     /transl_table=11
                     /translation="MTSTVPTAVQHTDAQPPITMFGPDFPYAYDDFLAHPAGLGQIPAT
                     EHGSEVAVIGGGLSGIITAYELMKMGLRPVLYEADRIGGRLRTVGFEGCDPSLTAEMGA
                     MRFPPSSTALQHYIDLVGLETRPFPNPLSPATPSTVVDLKGESHYARTVDDLPQVYRDV
                     AAAWNACLEEGARFSDMNRALRERDVPRIRAIWSELVEKLDNQTFYGFLCASPAFSSFR
                     HREIFGQVGFGTGGWDTDFPNSILEILRVVYTEADDHHRGIVGGSQQLPLRLWEHEPAK
                     AVHWPPGTSLASLHDDRPRPAVTRLGRTAGNRITVTDADGDIRTYRAAVFTGQSWLLLS
                     RIACDDALFPIDHWTAVERTHYMESSKLFVPVDRPFWLDEDPATGRDTMSMTLTDRMTR
                     GTYLLDDGPGRPAVICLSYTWCDDSLKWLPLSPNERMEVMLKSLGEIYPGVDIRGHVIG
                     NPVTVSWENEPWFMGAFKANLPGHYRYQRRLFTHFMQDGLPADRRGLFLAGDDISWTAG
                     WAEGAVQTALNAVWGVMHQFGGATDPSNPGPGDVFDAIAPVELPED"
     gene            complement(18119..18820)
                     /locus_tag="CP967_RS29070"
                     /old_locus_tag="CP967_29145"
     CDS             complement(18119..18820)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006123149.1"
                     /locus_tag="CP967_RS29070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29145"
                     /product="DUF5995 family protein"
                     /protein_id="WP_190175389.1"
                     /transl_table=11
                     /translation="MDRFEQVAVPAGPVAGVGGVTERMRALGSGWPPGDGVAVFNQVYL
                     SVTEAVGGRLADGSFPDPEALSALDVRFAERYLSAVDAESGGGRPPDCWRPLFAYRRHP
                     GVRPLQFALAGINAHIGHDLALAVVDTCRTLDCGPRDLEDEFERVGDLLVLLEEQIRED
                     LMPGPDLLELADPLTHLAGTWSLERAREAAWSAARVLWRLRAVPSLAEEFRARMDAGVG
                     LVGRFLLTPCR"
     gene            complement(18984..20390)
                     /locus_tag="CP967_RS29075"
                     /old_locus_tag="CP967_29150"
     CDS             complement(18984..20390)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010057370.1"
                     /locus_tag="CP967_RS29075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_29150"
                     /product="solute carrier family 23 protein"
                     /protein_id="WP_150490813.1"
                     /transl_table=11
                     /translation="MGGLGVRWTLHGDGKTPAPGAVVRPDERLSWPRTFGLGAQHVVAM
                     FGASFVAPVLMGLDPNLAIMMSGVATAVFLLATRGRVPSYLGCSLSFVGVAATIRASGG
                     TSATVTGAVLVVGAVLFLVGLTVRRFGARIIHAAMPPVVTGAVVMLIGFNLAPVTASTY
                     WPQDQWTALLVMLFTGLAVVCLRGFFSRIAIFLGLVFGYVLSWVLDLVFGKIHSPAGGA
                     EAVDHWRLDLSGVADADWIGLPSFHAPAFEWSAILVALPVVIALIAENAGHVKAVGEMT
                     GDSLDDKLGTAIAADGAASVLSTAVGGPPNTTYSENIGVMAATRVYSTAAYWAAACFAL
                     LFGLCPKFGAVVAAIPGGVLGGITVILYGMIGLLGAQIWLNAGVDLRNPLNLVPAAAGI
                     IIGVGGVSLKISDNFELGGIALGTLVVITGYHVLRAFAPAHLKTQEPLLDEGTSRYDAE
                     GGPGRGPGAG"
     misc_feature    complement(20465..20478)
                     /note="TFBS match to RpoN, Regulator of nitrogen
                     assimilation and virulence, confidence: strong, score:
                     17.65"
                     /tool="antismash"
ORIGIN
        1 cctggcccgc accgcggtgg cccgcggcgc ccggacgacc ctgatcgggg cgaacaccgc
       61 actgcccgac ccggccgggg ccgacgtcct gcgggtgggg acggccctgg agctgcgcga
      121 ggcggtgcgg aaggcggcgg ccgacgcgga cgtggtggtg atggcggcgg cggtcgccga
      181 tttccggccc gccgagtacg ccacgggcaa gatcaagaag aaggacggcc aggagccggc
      241 ccccctcgtg ctggtccgca accccgacat cctcgcggag gtctccgccg ggcgcgcccg
      301 ggccgggcag ctcgtcgtcg gattcgccgc cgagaccgac gacgtcctcg ccaacggccg
      361 ccacaagctc cgccgcaagg gctgtgacct gctggtcgtc aacgaggtcg gggaggacaa
      421 gaccttcggt tccgaggaga acgaagccgt ggtgctcgga gcggacggct ccgagacggc
      481 tgttccgtac ggccccaagg aagtgctcgc cgacgtggtg tgggacctgg tggcggcccg
      541 gctcggctga tccggcccct tcgccggccg cgtccgcggg cggcgcgaga ggggagaacc
      601 cgccggaatc cgggccgggg cgcacggatt ccggcccggc gggggatact cggacgagca
      661 cgtgcctgac ccgtgggtaa agagtgattt tcgtaccgtg gtcaacggtg tggcaggtca
      721 cagatctccc aaggggcgag acacgtgacc caatcaccgg aagcgaccga taaactggcc
      781 gccggacgtg ccgggcgcag ctcccggtgg tccaccaatg atcagccagc agccgctgca
      841 accacaggga gcgatgtgtc ccgccgtctc ttcacctcgg agtctgtcac cgagggtcat
      901 cccgacaaga tcgccgatca gatcagcgac accgttctcg atgcgcttct gcgtgaggat
      961 ccttcttcgc gtgtggcggt cgagaccctg atcactacgg gtctcgtgca tgttgcggga
     1021 gaggtcacga ccaaggctta tgccgatatt cccactcttg tgcgtaacaa ggtgctggag
     1081 atcggttacg actcctcgaa gaagggtttc gacggggctt cgtgtggtgt ttcggtgtcc
     1141 atcggggcgc agtcgccgga catcgcgcag ggtgtggaca ccgcgtacga gaagcgggtc
     1201 gagggggatg aggacgagct cgacaagcag ggtgccggtg atcaggggct gatgttcggg
     1261 tatgcctgtg atgagacgcc ggagttgatg ccgttgccga ttcatctggc gcaccggttg
     1321 tcgcggcggt tgtcggaggt gcgtaagaac gggacgattc cgtatctgcg gccggacggc
     1381 aagacgcagg tgacgatcga gtacgacggt gacaaggcgg tgcgtctgga cacggtggtg
     1441 gtgtcttcgc agcatgcttc ggacatcgat ctggattcgt tgctggcgcc tgacatccgt
     1501 gagttcgtgg tggagcatgt gctgggtcag ctggtggggg acggtatcaa gctggatacc
     1561 gagggttacc ggttgttggt gaatccgacg gggcgtttcg agatcggtgg gccgatgggg
     1621 gatgcgggtc tgaccgggcg gaagatcatc attgacacct acgggggtta tgcccgtcat
     1681 ggtggtggtg ctttctcggg gaaggatccg tcgaaggtgg accgttcggc ggcgtacgcg
     1741 atgcggtggg tcgccaagaa cgtggtggcc gcggggctgg cggcgcggtg tgaggtccag
     1801 gtcgcgtatg cgatcgggaa ggcggagccg gtgggtctgt tcgtggagac cttcggtacg
     1861 gcgacggtgg acacggagcg gatcgagcac gcgatcggtg aggtcttcga tctgcgtccg
     1921 gcggcgatca tccgtgatct cgatctgctg cgtccgatct acgcgcagac cgcggcgtac
     1981 ggtcacttcg ggcgtgagct gcccgacttc acgtgggaac gcaccgaccg catcgacgca
     2041 ctgcgtgagg ccgccggcct gtaggacggc ccgccgtttc cgtacaccgg ggcccggaca
     2101 ccgcgcaggc ggtgcccggg ccccggcgcg tgccccgggg gcgcggggtc cgggagcggg
     2161 gcggcgctgt cggtggcctc tggtaggaag gatgccgtga gcagcgacga cgagcggtcc
     2221 gacgagcccg gcacaggaca gccggagcag ctcgcgctca tccgggagac cgtccgccgg
     2281 gccgaggtgc cgcgcgcgaa gccccggacc tggcggggcg ccgcgctcgc cgggaaactg
     2341 cccgtcgccc gcgtcctggt gaacaagggc gtgctccacc tcgaccagta cttcgactac
     2401 gcggtgcccg aggagctcga cgccgacgcg cagcccggcg tccgggtccg cgtgcggttc
     2461 ggcgcgggcg gccggcaggt gcgcggcgga cgccgcgagg gcggcgggct catcgacggg
     2521 ttcctcgtcg agcgccgggc cacctccgac tacccgggcg ctctggccgc cctcgcctac
     2581 gtcgtctcgc ccgagccggt gctggggccc gaactgctcg cactctcccg ggccgtcgcc
     2641 gaccgctacg cgggcagtct cgccgatgtg ctccagctcg ccgtgccccc gaggaacggc
     2701 agagccgagt ccaggccctc gcccgccccg ccgcccccgc cgcccgtacc ctcgcccgga
     2761 ccgtgggagc ggtacgccca gggcccgggc ttcctgcggg cgctggccgg gggggaggcg
     2821 ccccgggcgg tgtggaccgc gctgccggga ccgcactggc ccgaggagat cgcccgcgcc
     2881 gtcgcggcga cgctcgcctc gggccggggc gccctcgtcg tcgtaccgga cgggcgcacg
     2941 gcgggccggg tggacgccgc gctgaccgct ctcctgggca agggccacca cgccctgctc
     3001 accgccgagt ccggcccgga gaagcgctac gggcagtggc tcgcggtccg gcgcggatcg
     3061 gtgcgcgcgg tcgtcgggac cagggccgcg atgttcgccc ccgtcaccgg tctaggcctg
     3121 gtcgccgtct gggacgacgg ggactccagc cacagcgacg acaacgcccc cttcccgcac
     3181 gtgagggagg tcctggagct gcgcgcggcg cacagccggt gcgccttcct gctgggcggc
     3241 gtcaactgca cggtggaggc ggcccagctg gtcgagagcg gctgggcgct gccgctgcgc
     3301 ccggaccggg agcaggtccg gatcgcggcc cctctcgtcc gtaccgtcga cgacggcgag
     3361 ctggcacggg acggcgcggc gcgctcggcg cggctgccca gcctggcctg gcagaccgta
     3421 cgcgacggcc tgcgcgacgg ccccgtcctg gtccaggtac cgcgccgggg atacgccccc
     3481 cgcctggcct gcgagcgctg ccgggagccc gcccggtgcc ggcactgcgc gggcccgctc
     3541 caggcgccgg accggcagaa cctggaatgc gcctggtgcg ggcggaccga gacggcctgg
     3601 aactgcgcgg cctgcggggg caccggactg cgggcgcaga tcgtcggggc ccgcaggacc
     3661 gccgaggagc tgggccgggc cttcccggac gtccccgtac ggacctcggg gcgcgaccac
     3721 gtcctggact ccgtacccgg acagcccgcg ctggtcgtca gcacacccgg ggccgaaccg
     3781 gtggccgagg gcggctacac ggccgcgctg ctgctggacg gctgggcgat ggtcggccgc
     3841 cccgacctgc gggccgggga ggaggccctg cggcgctgga cggccgccgc cgccctggtc
     3901 cgcggccgtc cggagggcgg gacggtcgtc gtcgtcgccg aaccggccct gcggcccgtc
     3961 caggcactgg tgcgctggga cccggtcggc cacgcccgcc gcgagctcgc cgaacgcgcc
     4021 gaactcggct tcccgccggt gtccaggatg gccgcggtca ccggcccgcc cgaagccctc
     4081 gccgccttcc tggccacggc ggaactgcct gccgaggcgg agatcctcgg acccgtcccg
     4141 gtgcccgcgg cgcccacggg ccggccccgc aggccgggcg acgccccacc gggcgctccc
     4201 cgggaacgag ctctggtcag ggtcccgccg gggcgcggcg cggcgctcgc cgccgccctg
     4261 aaggcggcgt cggcggcccg gaccgcccgg gggagcggcg atccggtacg catccggatc
     4321 gacccgccgg acatcggctg aggccgggga gcagccggag cggcggtgcc gcggcccgtt
     4381 ccccggcctc gggccacctg gcttcggggc cgcccggctt cgggccgccc gccccccagg
     4441 gcccgtgcgg cgccccggag ggcgcctttt gccgccgtca gccgttgcgc ggcccgggga
     4501 aggccccggg ccgcaactcc tcacgcgaca ccgccccgtc gggcgacggc gggggcggct
     4561 gcggaggcat cgggcgggcc gacggcacga cgggcagcgg ctgccccggg cccgccgccg
     4621 cggacgcctt acggggcgcg gcgccctccg cctcggcggc cggaggctgc ggggcgctgc
     4681 gccgggtgcc gtaacgacgg tgcaccgcct gcttggtgac accgagagcc gaaccgaccg
     4741 cgtcccacga gaaaccgagc gagcggtcga agtccaccgc cgccgtcacc aacgtctcga
     4801 cgctgtcccg cagttcctgg gccagccgga ccgtgggggc gggggcccgg ccgtagacga
     4861 cgaagcccgc ggaggggccg gagcggcgcg gacggtagac gttgccgagc tgcgcagtga
     4921 gggtgcgcag cgcgtccacc tgccgccgga cccgctcgat gtcacgcacc aacaggtgca
     4981 gactggcacg cgcttgggcg tcatgggttg cgtggtcggc catgaacaag cctctcgaac
     5041 cggcgttgag ggatcggacc gcgtcgcggc ggcccacttc ggtcaatctc ccttgaccaa
     5101 cgcgccaccc gccgccgggt cacgcatcag gggcgtatgc gcatatgcgc ggggcgcgcg
     5161 gacccgtgta cgcccccgcc gggcagcgct tcggcgcgga ggccgggacg gggcgcggac
     5221 cacccgccgc cgccccgtgc ccttccccgc aggccaccgg ggtccgcccg cggatcaggc
     5281 cctagactgg tgcgctgctc gtcgtccgtt ctccgccgag aggcagcgcg ccacccatga
     5341 agctggtctt cgcaggcacc cccgaggtcg ccgttcccgc cctggacgcc ctgatcgcct
     5401 ccggacgcca cgaggtggcc gcggtcgtca cccgccccga cgcgcccgcc gggcgcggac
     5461 gccggctggt cgccagcccc gtcgccgaac gcgccgagga ggccggcatc gaggtgctca
     5521 agccggcccg gccgcgcgac gaggacttcc tcgcccggct ccgggagatc gggccggact
     5581 gctgccccgt cgtcgcctac ggcgcgctgc tgcccggggc cgcactcgag atccccgccc
     5641 acggctgggt caacctgcac ttctccctgc tccccgcctg gcgcggagcc gcacccgtcc
     5701 agcacgcggt gatggccggt gacgaggtga ccggcgcgtc gaccttcctg atcgagaagg
     5761 gcctggactc cggaccggtc tacggggtgc tgaccgagga ggtacggccc acggacacca
     5821 gcggtgacct gctcacccgg ctcgccttcg ccggagcggg acttctcgcc gcgaccatgg
     5881 acggcatcga ggacggcacc ctgcacgccg taccgcagcc cgccgaaggc gtcaccctcg
     5941 cacccaagat caccgtcgag gacgcccagg tgcactggca ggcccccgcg ctgcgggtcg
     6001 accgggtggt gcgcggctgc accccagcgc cgggcgcctg gaccctcttc cgcggcgaac
     6061 gcctcaagct ggtccaggcc gtcccggtcc ccggccgcac cgatctcacc cccggcgaac
     6121 tctccgcggg caagaacaac gtgtacgtgg gcacgggctc ccacgcggtg gaactcctct
     6181 gggtccagcc ccagggcaag aagccgatga aggccgccga ctgggccagg ggcgtacgca
     6241 tcacctccgg cgaactcctg ggggcctgag ggcggggttt cccgcggcgg gtcccgggag
     6301 cccgggagcg gccccggggg gcgggccgtc cgccccgggg ccgtcgtagg ctggacggga
     6361 tcgccccctc accctccgcg gagcaccttt cacgtgaacg accagcagcg tcgccgtccc
     6421 gccaagcagc accgacgccc caagaaggac cccgtccggt tcctcgcctt cgaagcactc
     6481 agggccgtcg acgagcgtga cgcctacgcc aacctcgtgc tgccccccct gctcaagaag
     6541 gcccgcgcca agggggattt cgacagccgg gacgcggcgc tcgccaccga gctggtctac
     6601 ggcacgctgc gccgccaggg cacctacgac gcgatcgtcg ccgcgtgcgt cgaccggccg
     6661 ctgcgcgagg tcgacccgcc ggtcctcgac gtgatcgaga tgggtgtgca ccaactgctc
     6721 ggcaccagga tccccaccca cgcggccgtg tccgccagcg tcgagctggc cagggtcgtc
     6781 ctgggggagg ggcgcgccaa gttcgtcaac gcggtgctgc gccgggtcac ggcccatgac
     6841 ctcgacggct ggaccgagcg ggtcgcgccc ccctacgacg aggaccccga ggagcacctc
     6901 gccctcgtcc actcccaccc ccgctgggtg gtctccgccc tctgggacgc cctgggcggc
     6961 ggccggagcg ggatcgagga cctcctggag gccgacaacg agcggcccga ggtgaccctg
     7021 gtggcccgcc ccgggcgctc cacccccgag gagctcctca ccgccctcgg cgaggagcgc
     7081 ggcctgcccg gccgctggtc cccctacgcc gtacgcatgg ccgagggcgg cgagcccggc
     7141 gccctggccg ccgtacggga gggcggagcg ggggtgcagg acgagggcag ccagctcgtc
     7201 gcggcggcgc tcgcccacgc gcccctcgaa ggtgacgaca cccgctggct cgacggctgc
     7261 gccggcccgg gcggcaaggc cgccctgctc ggtgcgctcg cggcggagcg cggcgcggca
     7321 ctgctcgcgt ccgagaagca gccgcaccgg gcccgactcg tcgaacgggc gctggccggc
     7381 aaccccggcc cctaccaggt gatcacggcg gacggcaccc gcccgccgtg gcggcccggc
     7441 tccttcgacc gggtcctgat ggacgtaccc tgctccggcc tcggcgcgct gcgccgccgc
     7501 ccggaagcgc gctggcgccg ccgccccgag gacctggagg gcttcgcccc cctccagcgc
     7561 ggtctgctgc gcgaggcgct gaaggccgtc cgggtcggcg gcgtggtcgg ctacgccacc
     7621 tgctccccgc acctggcgga gacccgggtg gtggtcgagg acgtgctcaa ggggcggggc
     7681 gggcagccgg ccgaagcgga atgggtggac gcccggccgc tgttccccgg cgtaccggcg
     7741 ctgggcgacg ggcccgacgt ccagctctgg ccgcatctgc acggcaccga cgcgatgtac
     7801 ctggcgctgc tgcggcgcac ggcctgagcg ggcgcaccgg acgcaccggc gccccggcgg
     7861 gggagacctc tccggggccg gccggagcgc ggggcgcccg gccctggcct ggtttcggtc
     7921 ctggttccgg cccggccctg atcccggccc tggcctcgcc caggcggtac ggccccggct
     7981 ccggaggtga aaagccggaa atgcgcgaac tgtaatgatc ccgtgaggct ttgggacgca
     8041 ccggggcggg gaagtggccc ggagcatggc aggcttggcc catggcgcag atcaatccca
     8101 gcatcctgtc cgccgacttc gcgcgtctcg ccgaggaggc gaaggccgtc gacggagccg
     8161 actggctcca cgtcgatgtc atggacaacc acttcgtccc caacctgacc ctcggcgtgc
     8221 cggtggtcga ggcgctgagc aaggccacgg acaccccgct ggactgccat ctgatgatcg
     8281 aggacgcgga ccgctgggcg ccgcagtacg tcgaagccgg cgcgggctcc gtcaccttcc
     8341 acgtggaggc cgcggcggcc ccggtgcggc tggcgcggga gatcagggcg aagggggcgc
     8401 gcgcctcgat ggcgctcagg cccgcgacgc cgatcgagcc gtacgaggac ctcctccccg
     8461 agctcgacat gctgctgatc atgacggtgg agccgggctt cggcggccag gcgttcctcg
     8521 acatcatgct gccgaagatc cgccgcaccc gtgagctgat ctccaagcac ggtctcgaac
     8581 tgtggctcca ggtcgacggc ggggtctccg ccaccacgat cgagcgatgc gcggaggccg
     8641 gcgcggacgt cttcgtggcc ggctcggccg tctacggggc ggaggacccg gccgaagcgg
     8701 tacgcgcgct gcgcgcccgg gcggaggcgg ccacggccgg cgccccctgg gcatgcggac
     8761 actgaacaaa gggcagatga acgcggcccc acgggcctga tcaaggatcg ccggatctga
     8821 caggatggcg gcgtatcgag cgcaagagag ttgagggaga tcgcggtgtc tggcatctcg
     8881 gcgggtcggt cagccatgcg gatgggaccc gcggagctgg tccaggcggc ggccatggcc
     8941 cgccggttct atctcgaggg gaaatcgaag atccagatcg ccgaggagtt cggcgtgagc
     9001 cgcttcaagg tggcccgggt cctggagacg gccctcgaac gtgatctcgt acggatcgag
     9061 atcagggttc cggcggagct cgacgcggag cgctccgacg cgctccgcgc acggtacggc
     9121 ctgcggcacg cggtcgtggt ggagtccccg gcggaggagc aggacgacgc cgccgacccg
     9181 gagaacctgg gcgaggtggc cgccgacctg ctcggcgagc tggtgaacga gggcgatgtg
     9241 ctgggcctgg cctggggccg gtccaccatc cacatggcgg cggccctcga ccggctgccg
     9301 ccctgcaccg tcgtacagct gaccggggtc tacgacgccg ggacggccga gcgcggctcc
     9361 gtcgaggcgg tccgccgggc cgcccaggtc tccggcggcg aggcgcatcc gatctacgcg
     9421 ccgatgctgc tccccgaccc ggccaccgcg gcggccctgc gccaccagac ggggatcgcc
     9481 cgcgccttcg agcacttcga caaggtgacc gtcgcggccg tctccatcgg ttcgtgggaa
     9541 ccgggcatct ccaccgtcca cgacatgctc tcggacgacg agcgggcgca ctacgcctcg
     9601 ctcggggtgg cggcggagat gtccgcgcac ctcttcgacg ccgacgggcg cagggtcggc
     9661 cgggacctcg gcgagcggtg catcaccgtg gaggcggacc ggctgcgccg gatccccgag
     9721 gtcgtcgcca tcgccggcgg ccagcgcaag gcggcggcca tcggcgcggt gctgcggtcc
     9781 gggctcgtca ccagcctcgt cacggacacg gcggccgccg actacctgct gacggagtcg
     9841 gccgccggtc ccaggccggc cctggagcgc gccgacccgg acgactgagc cgcgtccggc
     9901 ccggacgggg gccgcgcccg gccgggccgg agcccggccg gacagggggc gccggacacc
     9961 ccgtgcgggt ggagcccccc ggcgcccttc ccccgcccgc tcagtcgccc gtacgcggag
    10021 ccgccacggc gccgtccgtg gccacaccga ggaccgtctc ctccaggtac tccccgggcg
    10081 ccgcgtactg gctgacggcc gccgggttgt agcggggcgt ctgccgcgac cagtccaggt
    10141 tgccgcgcat ccagctccgc atcccgtcca gatagggcac gagcgtccgg gtcagctgcg
    10201 ggaacacctc cagcagctcg tcctcggcgg tgaggaaccg ctcggtctcc gtggctatcg
    10261 ccgcgcagac gtgttcgagg gcctgccgct cgccgtaacc ccggtggtgg cgcaccaggt
    10321 ggacgaggtt gtggatttcg ccgagcatct gctccttctc gtaggagtag acgtcgttgg
    10381 cccagcacac cacgttgcac gaggcctcca gcgcggtgac gaaccgggga tcgccatgga
    10441 ccgcctccgg ggcctgtatg cccgcgacga tctcgatgag gtccatgcac acatggatcg
    10501 ccccggtgtg gcggcgcttg gagatgtacg cggcctcgct cggtaccgca ccggtcgcgc
    10561 ggttcccggc ctcccaggtg gtggtcatcg tcagataggt catgaggtgc cccgtgaagc
    10621 gggtgcgcca gtggggcgcc gcgcgcggga ccgtgcgttc ccacaggtcg gcgagggcga
    10681 cgagggccgc gggcgcctcc tccccgggcg ggacgcgggg tgcggtgcct tcgaccaccg
    10741 cccgcatccg cgcgaccacg tcccgcacgc gctcggggtt ccggcccagg tgcccgtcgt
    10801 ccagctggtc gtcgacgagg aacagccaca cgaaccagtc ggcgaccaga tccaggtgct
    10861 cggggctcgc ggtggggtgg accatgccga cgaaggaccc gaagtcggcc tgttcgaaac
    10921 gggcccgtgc ggactcccgg tgcaccaggc cggtgcgccg ggtccactcg tcgagatgcg
    10981 cgcgggtgtg cgcgacgtgc ggattgctcc gctgcgggaa cgggcagtag atgtccggca
    11041 gttcgctctc cacaggtgtg tccgggtcct ctccggtcga aggcgtgcgg gggcaccccg
    11101 ggcaccggtg ggcggacgcc ggacgccccg gggacctgcg cttttgaagc tacctgaccc
    11161 tctgtcaccc ggtccagaga agacgatcac accgatcggc cgggagttcg agcaaggtcc
    11221 cccggcaagc cccccccgga cggttaccgg gtaccggggc tgccccgggc gggtaccggg
    11281 cagggcgacg gccggtctcc gggagggcgg gcttttgccc cgcgccggcc ccgggtcggc
    11341 gcaacgaccg gcaccgggac ggaccgcccc ttgtgggaag ctacgaacac ggggtgcgtc
    11401 tgctgtgcct tcggaggcgt gacctgcgcc gattcccgtg taacgatggg catcatgcgt
    11461 tttctcgagc ccggaaccgg ccgctacacg gctacccctt cggtccctta cgacctcacg
    11521 tacgacgatg tcttcatggt ccccggccgt tcctcggtcg gttcccggca ggcggtggac
    11581 ctgtcctcgc cggacggcac cggcaccacc atcccgctcg tggtcgcgaa catgaccgcc
    11641 atcgccggcc gccggatggc cgagaccgtg gcccgccggg gcgggctggt cgtcattccg
    11701 caggacatcc cgctcgatgt ggtcaccgag gtcatcggct gggtcaagaa gcgccacctc
    11761 gtgctggaca ccccgatcgt gctggcgccc ggccagaccg tcgcggacgc cctgtccctg
    11821 ctgcacaagc gggcccacgg agcgggtgtc gtcgtcgacg cggaacaccg gccggtcggt
    11881 gtggtcaccg accacgacct ggccggggtg gaccgcttca cgcagctgtc cgaggtcatg
    11941 tccaaggacc tggtggtact cgacgccggg atcgacccgc gtgacgcctt caaccggctg
    12001 gacggcgcca accgcaagct ggcccccgcg gtggacgcgg acggcaggct ggtcggcatc
    12061 ctcacccgca aggccgcgct gcgggccacg ctctacaccc ccgccacgga cgccgacggc
    12121 aagctgcgtg tcgccgccgc cgtcggcatc aacggcgacg tggcgggcaa ggcggagcag
    12181 ctgctcgccg cgggcgtgga caccctggtc gtggacaccg cccacggcca ccaggaatcc
    12241 atgatcagcg cggtcgccgc ggtgcggaag ctggacccgg gggtgccggt cgtcgcgggc
    12301 aacgtcgtcg ccgccgaggg ggtgcgcgat ctgatcgagg ccggtgccga catcatcaag
    12361 gtcggcgtgg gccccggtgc catgtgcacc acccgcatga tgaccggtgt gggacgcccg
    12421 cagttctccg ccgtactgga gtgcgccgcg gaggcccgca agcacggcaa gcacgtctgg
    12481 gccgacggcg gggtccgcca cccgcgtgac gtcgccatgg cactggccgc cggcgcctcc
    12541 aacgtgatga tcggttcctg gttcgccggt acctacgagt ccccgggcga cctccagcag
    12601 gcggccgacg gccgcttcta caaggagtcc ttcggcatgg cctcggcgcg ggcggtcagg
    12661 aaccgcacgt cggaggagtc cgcctacgac cgggcccgca aggggctgtt cgaggagggc
    12721 atctccacct cgcggatgtt cctcgacccc gcccgccccg gggtggagga cctgatcgac
    12781 tcgatcatcg ccggggtccg ctcctcctgc acctacgcgg gcgccgcgtc gctggaggag
    12841 ttcgccgaga aggccgtcgt gggcgtccag agcgccgcgg gctacgccga gggcaagccg
    12901 ctgcacgcca gctggagctg accatccgcc cgccgtgcac aggtgccctt cccggaatag
    12961 tccgggaggg gcacccgcgc gtgtgcgggg ccccgctccg gggcgcccgc cggggagggg
    13021 gtccccgcgg atccgtaccg gggccagggc ctttccacag ggccggtcgg caccttcaac
    13081 tctgctgttt tataagtaat atgaatgccg atcagctgcc cgtccccctc tgcggtaagg
    13141 gaatccatgt ctgccttctt caccgatctg gcccttcagt acatcgacgg tgagtggagg
    13201 ccgggaaagg gcgcctggga catcatcgac ttcaacccgt acgacgggga gaagctggcg
    13261 tcgatcaccg tcgccacggc cgacgaggtc gaccaggcgt accgggcagc cgagcgtgcc
    13321 caggaggggt ggggccggac caacccctac atccgccggg ccgtgatgga gaaggcgctg
    13381 cgggtcgtcg aggagcgcga ggccgagatc gccgaggcga tcgtcgcgga gctcggcggc
    13441 acccatgtca aggccgggtt cgagctgcac ctcgccaagg agttcctgcg cgaatcggtc
    13501 cagctcgccc tgcgcaccac cgggcagatc ctcccgtcgc cgaccgaggg caaggagaac
    13561 cgggtctacc gcgagccggt cggggtcgtc ggcgtcatca gccccttcaa cttccccttc
    13621 ctgctgtcgc tgaagtcggt ggcgcccgcc ctcgccctcg gtaacgccgt cgtcctcaag
    13681 ccgcaccaga acacccccgt ctgcggcggg accctggtcg ccaaggtgtt cgaggaagcc
    13741 ggtctcccgg cgggactgct gaacgtcgtg gtcaccgaca tcgccgagat aggcgacgcc
    13801 ctgctggagc accccgtccc gcggctgatc tccttcaccg gatccgacaa ggtcgggcgg
    13861 cacgtggcga ccgtctgcgc gtcccacctc aagcagaccg tgctcgaact cggcggcaac
    13921 agcgcgctga tcgtcctcga cgacgccgac atcgactacg ccgtcgatgc cgcggtcttc
    13981 agccggtacg tgcaccaggg ccaggtctgc atggcggcca accgcatcct cgtggaccgg
    14041 gccgtcgcgg acgagttcac cgagaagttc gtcgccaagg tcgcctccct gcggatcggc
    14101 gaccccgccg acccggcgac ccacatcggc ccgctgatca actcctcgca ggccgaggcg
    14161 gtctccaagc tggtcgaccg gacggtcggg gaaggcgcca cggcgctgct gcacggcacc
    14221 gccgacggca acctggtgag cccttccgtg ctcacggaca tagccgccgg ctcgcccgtg
    14281 ctgcaggagg agatcttcgg ccccgtcgcc ctgctcatcc ccttcgacgg cgaggacgag
    14341 gccgtccgga tcgccaacga caccccctac ggactgagcg gcgccgtaca caccgccgac
    14401 gtcgagcgcg gggtgcgggt ggggcggcgc atccgcaccg gcatgatcca catcaacgac
    14461 ggaacggtcc acgacgagcc catcgtgccg ttcggcgggg agaagaactc gggcctggga
    14521 cggctcaacg gggacgcgac cgtcgatgcc ttcaccaccc ggaagtggat ctcggtgcag
    14581 cacggccgtt cacggttccc cttctgagcc ggcggctccg gcgcccgggt cccgcgcggg
    14641 agcgcgggtg agcccatggt gtacttcggg gggcggcccg ggccgccccc cgattccgcc
    14701 cgcagagaag tgaaccgccc gacgtgcgcc tgaacgacct cgacgaacgc atcgtccacg
    14761 ccctcgccga agacgcccgg cgctcctacg ccgacatcgg cgcggtcgtc ggcctgtccg
    14821 ccccggcggt gaaacgccgg gtggaccggc tgcgcgccga aggcgccatc accggcttca
    14881 ccgtccgggt ggacccggga gcgctcggct gggagaccga ggggttcatc gagatctact
    14941 gcagccgcaa caccgcgccc gaggcgatca ggcagggcct ggcccgcttc cccgaggtcg
    15001 cctccgcctc caccgtgacc ggggaggccg acgcggtcgt ccaggtgttc gccgccgaca
    15061 tgcgccactt cgagcaggta ctggaacgga tcgcgggcga gccctacatc gaacgcacca
    15121 agtccgtcct ggtgctctcg cccctgctgc gccggtactc ccagggtccg cccgcctgaa
    15181 ggcgccgcgc gggccgagcc ccgccccgcg cgggaggcca tggtgcccgc ccggccccgg
    15241 cacgcagccc cgtccggccg gccgggtcgt ggccgggagc ggcggagggc gaccccccgt
    15301 acgcgatcgc agccccgggc ccggggcggg gcccgccccg ggcggtccgg atcgcctttc
    15361 ggcccactcc tgacctgcgg tgacgtccgg cgcaacgaat cgccgccgct gcggccctcc
    15421 acgcaacgga tcgacggtgg acgcgcaaca tccgcgtctt gtcggccccg atcgcggccc
    15481 cgtaccttcg atacgtctcc ccgccccgcc cgcaccgtcc gaggtcagcc atgccgctgt
    15541 tgcgtaccgc cctgctccag agctccggac gccccggcct cgtgggccac aacctcgcgc
    15601 tgctcgacga ggcggccgga cgggccgccg ccgcgggagc ccgtctgctg gtcagccccg
    15661 aactcttcct caccggctac gccgtggacg acgccctgcc cggcctcgcc gaacccgccg
    15721 acgggcccgg ggccgaggcc gtctccgcca tctgcgtacg ccacggcatc gccgtcgcct
    15781 acggctaccc ggagcggtcc ggcggacggc tcttcaacgc cgtccagctc ctcggcccgg
    15841 acggcacggc gctcgccggc taccgcaaga cccacctcta cgggtccttc gagcagcgct
    15901 ggttcacccc cggcgaccgg accgtggtgc aggccgcgct ggacggcgtc cggatcgggc
    15961 tgctgatctg ctacgacgtc gagttcccgg agaacgtccg ggcccacgca ctggccggca
    16021 ccgacctgct gctggtgccg accgcgctga tgcggccctt cgggttcgtc gccgaatccg
    16081 tcgtaccggt ccgcgccttc gagaaccagc tgtacgtggc ctacgtcaac agggccggcc
    16141 cggaagggac gttcgacttc accgggctga gctgcctggc cggccccgac ggcaccgcac
    16201 gggcacgcgc cgggcagggc gaggagctcc tcctcgccga cgccgatccc gcccgcctgg
    16261 cggcctcgcg cgaggccaac acctacctcc gggaccggcg gcccgccctg tacggctccc
    16321 tgctctgaga cccccgcccc gcccgctcgc ccccgcacgt ccgccaagga gtccgtaccc
    16381 catgacgtcc acggtgccca ccgccgtcca gcacaccgac gcccagccgc cgatcaccat
    16441 gttcggaccg gacttcccct acgcctacga cgacttcctg gcgcaccccg cgggcctcgg
    16501 ccagatcccg gccaccgagc acgggagcga ggtcgccgtc atcggcggcg ggctctccgg
    16561 gatcatcacc gcctacgagc tgatgaagat gggcctcagg ccggtcctct acgaggccga
    16621 ccggatcggc ggccggctgc ggacggtcgg tttcgagggc tgcgacccgt cgctgaccgc
    16681 ggagatgggc gccatgcgct tcccgccctc ctcgaccgcg ctccagcact acatcgacct
    16741 ggtggggctg gagacccggc ccttccccaa cccgctctcc ccggccaccc cgtccaccgt
    16801 cgtggacctc aagggcgagt cccactacgc acggaccgtc gacgacctcc cccaggtgta
    16861 ccgggacgtg gccgcggcgt ggaacgcctg cctggaggag ggcgcccgct tctcggacat
    16921 gaaccgggcc ctgcgggaac gcgacgtgcc ccggatccgc gcgatctggt cggagctggt
    16981 cgagaagctg gacaaccaga ccttctacgg cttcctctgc gcctcaccgg ccttcagctc
    17041 cttccggcac cgggagatct tcggccaggt cggcttcggc accggcggct gggacaccga
    17101 cttccccaac tccatcctgg agatcctgcg ggtcgtctac accgaggcgg acgaccacca
    17161 ccgcggcatc gtgggcggca gccagcaact gcccctgcgg ctctgggaac acgaaccggc
    17221 caaggccgtg cactggcccc cggggacctc cctggcctcc ctgcacgacg accgccccag
    17281 gcccgccgtg acccggctcg gccgcaccgc cgggaaccgg atcaccgtga ccgacgcgga
    17341 cggcgacatc cgcacctacc gggccgccgt cttcaccggg cagtcctggc tgctgctgtc
    17401 caggatcgcc tgcgacgacg cgctgttccc catcgaccac tggacggcgg tggagcgcac
    17461 ccactacatg gagtcgtcca agctgttcgt gccggtcgac cgccccttct ggctggacga
    17521 ggacccggcg accgggcggg acacgatgtc catgaccctc accgaccgga tgacccgggg
    17581 cacctacctc ctggacgacg gccccggccg gccggccgtc atctgcctct cgtacacctg
    17641 gtgcgacgac agcctgaagt ggctgccgct ctccccgaac gagcgcatgg aggtcatgct
    17701 caagtcactg ggcgagatct acccgggcgt cgacatccgc ggacacgtca tcggcaaccc
    17761 ggtcacggtc tcctgggaga acgagccctg gttcatgggc gccttcaagg ccaacctgcc
    17821 cggccactac cgctaccagc gccggctgtt cacccacttc atgcaggacg ggctgcccgc
    17881 cgaccgcaga gggctcttcc tggccggtga cgacatctcg tggaccgccg gctgggcgga
    17941 aggcgccgtc cagaccgcgc tcaacgccgt ctggggcgtg atgcaccagt tcggcggcgc
    18001 cacggacccc tcgaacccgg gccccggcga cgtcttcgac gcgatagcgc cggtggaact
    18061 gcccgaggac tgacaggagc cgcgggaacc ggggcgggcg gaggacggcg gaaacgtatc
    18121 agcggcacgg ggtgagcagg aagcgcccca ccaggccgac ccccgcgtcc atccgcgccc
    18181 ggaactcctc cgccagcgac gggaccgcgc gcagccgcca cagcacccgc gccgccgacc
    18241 acgcggcctc ccgggcccgc tccaggctcc acgtacccgc cagatgggtc agcggatccg
    18301 ccagctccag caggtccggc cccggcatca gatcctcgcg gatctgctcc tccagcagca
    18361 ccaggagatc acccacccgc tcgaactcgt cctccaggtc ccgcggaccg cagtcgagcg
    18421 tgcggcaggt gtccaccacc gccagggcca gatcgtgccc gatgtgcgcg ttgatcccgg
    18481 cgagcgcgaa ctggagcggc cgtacgccgg gatggcgccg gtaggcgaac agcgggcgcc
    18541 agcagtccgg cggccggccg ccccccgact ccgcgtccac cgccgacaga tagcgctcgg
    18601 cgaagcgcac gtccagcgcg gacagggcct ccggatccgg gaacgagccg tccgcgagcc
    18661 tgccgccgac ggcctcggtg accgagaggt acacctggtt gaacaccgcg accccgtcac
    18721 cggggggcca ccccgaaccg agcgcgcgca tccgctcggt caccccgccg acaccggcca
    18781 ccgggccggc cggaactgcc acctgctcga accggtccat gcgggcaggc ttccagccgc
    18841 gggcccgccg cggtgccgac gggccgggac attcatcgga acgggcgaac accgggcacc
    18901 gggggaggga acgggcggcg cccggtgtac gggcacggac cgcccccggc cgggggaccg
    18961 ggggcggggc gggacgggcc cggtcagccg gcgccgggcc cccggccggg gccgccctcc
    19021 gcgtcgtacc gcgaggtgcc ctcgtccagg aggggctcct gggtcttgag gtgggccggg
    19081 gcgaaggccc gcaggacgtg gtagccggtg atcacgacca gggtgccgag cgcgatcccg
    19141 cccagctcga agttgtcgct gatcttcagg ctcacaccgc cgaccccgat gatgatgccc
    19201 gccgcggcgg gcaccaggtt cagcgggttg cgcaggtcca ccccggcgtt cagccagatc
    19261 tgggcaccca gcaggccgat catgccgtag aggatcacgg tgataccgcc caggaccccg
    19321 cccgggatcg ccgccacgac cgcgccgaac ttcgggcaca gcccgaagag cagcgcgaag
    19381 caggccgccg cccagtacgc ggcggtggag tagacccggg tcgccgccat gacgccgatg
    19441 ttctcggagt acgtcgtgtt gggcggtccg cccacggcgg tggacagcac cgaggcggcg
    19501 ccgtcggccg cgatggcggt gcccagcttg tcgtcgagcg agtcaccggt catctcgccg
    19561 acggccttca catgcccggc gttctcggcg atcagggcga tcaccacggg cagggcgacc
    19621 aggatcgccg accactcgaa ggccggggcg tggaaggagg gcagcccgat ccagtcggcg
    19681 tccgccaccc cggacaggtc cagacgccag tggtccacgg cctcggcacc gcccgccggg
    19741 gagtggatct tcccgaacac caggtccagc acccaggaca ggacgtatcc gaagaccagc
    19801 cccaggaaga tcgcgatgcg cgagaagaag ccgcgcagac agaccacggc cagaccggtg
    19861 aacagcatca ccagcagggc ggtccactgg tcctgcggcc agtacgtcga ggcggtgacc
    19921 ggtgccaggt tgaagccgat cagcatgacc accgcaccgg tcaccaccgg cggcatcgcc
    19981 gcgtggatga tccgcgcccc gaaacgccgc accgtcagac ccaccaggaa cagcaccgcg
    20041 ccgaccacca gcacggcacc ggtgacggtg gcgctggtgc cgccgctcgc ccggatcgtg
    20101 gccgcgaccc cgacgaagga gagcgagcac cccaggtagc tcggcacccg gccgcgcgtc
    20161 gccagcagga agacggcggt ggcgacaccg gacatcatga tggcgaggtt cgggtccagc
    20221 cccatcagga ccggcgccac gaaggacgcg ccgaacatcg ccaccacgtg ctgggcgccc
    20281 aggccgaacg tacgcggcca ggacagccgc tcgtcgggcc gcaccaccgc tccgggcgcc
    20341 ggggtcttcc cgtcgccgtg caaggtccag cgcacgccga ggccgcccat ggtcactccc
    20401 tgtgtggtgg gtgcggcgcg tccctgacga gcccgtcagg aaggccgccg ccgaaaagat
    20461 cagcgcaatg gtagtgccgt acggcgctga cctcgtgcgc gggtcccggc cgggcgggtc
    20521 cggtcagctc ccggccggga ccccgagcgc cccggcacgc ggggcgtcac cctccgcggc
    20581 cttccggtcg ccgccgcgca tcaccccggc ccccagcacc agcccgaacg ccagggccgt
    20641 caccagaccg aaggacacca gcagcgaggt cgcctcggcc agggcgccga tcgccgaggg
    20701 ggcgatcagc cccgaggtgt acgtgatggt ggcgacaccc gcgatggccc ggctcgggtt
    20761 gtccccgctg cgccccgccg cggcgaacgc cagcgggacg gcgaccgcga cacccaggcc
    20821 gatcagcccg aagccgctga gcgccagcgc cgtgttcggg gccgtcacca ccagcaggcc
    20881 gccggcggtg gccagcacac cgccggcccg gaccgtccgg acggcgccga agcggtccac
    20941 caccctgtcg ccggcgagcc gggcgacggc catcatcagg gcgaacgccg tcgtcgaggc
    21001 cgccgcgatg ccggccgagc tgccgagggt gtcccgcaga tagatcgccg acc
//
