LOCUS       NZ_CP023702            26317 bp    DNA     linear   CON 23-APR-2024
DEFINITION  Streptomyces nitrosporeus strain ATCC 12769 chromosome, complete
            genome.
ACCESSION   NZ_CP023702
VERSION     NZ_CP023702.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nitrosporeus
  ORGANISM  Streptomyces nitrosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7581562)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008704555.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:20:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,704
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,461
            CDSs (with protein)               :: 6,461
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 66 of 146
            Pseudo Genes (incomplete)         :: 106 of 146
            Pseudo Genes (internal stop)      :: 16 of 146
            Pseudo Genes (multiple problems)  :: 38 of 146
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4409687
            Orig. end                         :: 4436004
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023702.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..26317
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-i"
                     /region_number="21"
                     /rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..26317
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26317
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:16317](+)"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..16317
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(((Lant_dehydr_N or Lant_dehydr_C) and
                     cds(LANC_like and not Pkinase)) and not (YcaO or
                     TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     gene            847..1419
                     /locus_tag="CP967_RS19595"
                     /old_locus_tag="CP967_19655"
     CDS             847..1419
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609268.1"
                     /locus_tag="CP967_RS19595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19655"
                     /product="TIGR03086 family metal-binding protein"
                     /protein_id="WP_150489207.1"
                     /transl_table=11
                     /translation="MKKISELLETAAALTCPVVRGIDDARLDAPTPCAEYDVRALLNHL
                     FLVVTNFRALAAREEADFSTTPDVVTGDWRGRFEKETASLVAAWDASGAEDGVAGRMNL
                     PARTVGLMVLGDLVVHGWDLARATGRSFDAGPALVEVLEPGLAGMAPQARSMNVFGEPF
                     PLPAGAPAFDRVLALTGRDPGWSPAGA"
     gene            complement(1478..2218)
                     /locus_tag="CP967_RS19600"
                     /old_locus_tag="CP967_19660"
     CDS             complement(1478..2218)
                     /NRPS_PKS="Domain: Abhydrolase_1 (54-153). E-value:
                     1.9e-08. Score: 26.2. Matches aSDomain:
                     nrpspksdomains_CP967_RS19600_Abhydrolase_1.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018102972.1"
                     /locus_tag="CP967_RS19600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19660"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_150489208.1"
                     /transl_table=11
                     /translation="MRRRSPRRLLGALASAAIAFTLFSPASAAGAAEVPAASSVSSSAS
                     AAAPLSTGTPVVFVHGYTGSASNWVTAMSVFRLNGWSGSNLFAYEYDSYGDNVGNARGL
                     ASFVDNVKSRTGASKVAIVNHSMGGLVSQYYLKVLGGHSSVSHLASIAGANHGTTFAGA
                     CLIYTTCQQMYPGSSFIAQITSGDETPGSTRYASWYSACDGIILPYTSTRLSGATNNPV
                     LCQTHIGFLADTLVLGEIARFVAS"
     aSDomain        complement(1760..2056)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP967_RS19600_Abhydrolase_1.1"
                     /evalue="1.90E-08"
                     /label="CP967_RS19600_Abhydrolase_1.1"
                     /locus_tag="CP967_RS19600"
                     /protein_end="153"
                     /protein_start="54"
                     /score="26.2"
                     /tool="antismash"
                     /translation="PVVFVHGYTGSASNWVTAMSVFRLNGWSGSNLFAYEYDSYGDNVG
                     NARGLASFVDNVKSRTGASKVAIVNHSMGGLVSQYYLKVLGGHSSVSHLASIAG"
     gene            complement(2321..3550)
                     /locus_tag="CP967_RS19605"
                     /old_locus_tag="CP967_19665"
     CDS             complement(2321..3550)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1117:
                     sodium/hydrogen exchanger"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009192733.1"
                     /locus_tag="CP967_RS19605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19665"
                     /product="cation:proton antiporter"
                     /protein_id="WP_150489209.1"
                     /transl_table=11
                     /translation="MASPGTLVLILAAAALAPLLVHATGSRVRVPLVVFEIVLGVLIGP
                     QVLGWADPDEVIDTLADLGLSMLIFLAGYEIEFAAVRGDTLRRSLWAWPLSLALGIGLG
                     FLISGGAVFEAFVVGTALTSTALGTILPMLRDSGELRGRFGTVVSAFGAVGEFGPVVAM
                     ALLLSGRRPAESAALLAAFGAVTVLAVFWALRPRPAWFGRITERTLHSSGQFAVRFVML
                     LLACMLGLAEVFGLDVLLGAFAAGVLTRLVLHRAAPASSAEVLGRVEAMGFGFLVPLFY
                     VVTGIEFDLDALLHDPVALLLLPVFLLLFVLVRGGPVYLLAPRDLGRGDRAALALFAST
                     CLPLVVAITAIGVDQELLGTDRAASLVGAAMISVLVLPLAATRLRTALGGPGRRKPGPG
                     PDAAEGTEAW"
     gene            4009..4494
                     /locus_tag="CP967_RS19610"
                     /old_locus_tag="CP967_19670"
     CDS             4009..4494
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007446916.1"
                     /locus_tag="CP967_RS19610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19670"
                     /product="DUF1269 domain-containing protein"
                     /protein_id="WP_150489210.1"
                     /transl_table=11
                     /translation="MATLTVWKFDTPEGASDAEDTLLQLQKQELIKVLDAAVATWPEGE
                     KKPRTKQLHDLTGAGALSGTFWGMLFGLIFFMPLLGAAIGAAAGALGGRMADIGIDDDF
                     IDSVKTQVTPGTSALFLLSQDAVVERVREAFPSGHAQLLQSNLDSAQEARLREVFAD"
     gene            complement(4990..5370)
                     /locus_tag="CP967_RS19615"
     CDS             complement(4990..5370)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP967_RS19615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_150489211.1"
                     /transl_table=11
                     /translation="MVSVVSTVAAVVLVVTGGVAFMSRTSDAAHRAARDVVNATAPDSY
                     FGIQGVRICVQPLKGKLSVHNGPLPTDRPLLAFSTEGDVLYLWDPVRVREHGGPDPVMS
                     VRSAEVSTYAVSDGQSRCPEQP"
     misc_feature    complement(5352..5366)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 17.54"
                     /tool="antismash"
     misc_feature    complement(5394..5412)
                     /note="TFBS match to DmdR1, Iron(II)-dependent repressor,
                     confidence: weak, score: 21.57"
                     /tool="antismash"
     misc_feature    5657..5672
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.63"
                     /tool="antismash"
     gene            complement(5694..6323)
                     /locus_tag="CP967_RS19620"
                     /old_locus_tag="CP967_19680"
     CDS             complement(5694..6323)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP967_RS19620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CP967_19680"
                     /product="hypothetical protein"
                     /protein_id="WP_150489212.1"
                     /transl_table=11
                     /translation="MDDSPSGGSPISAAVGELEVPLPTAGFDERVDLVFRAPKRGRDQL
                     LAKGLCEQQGWAIRPADEQEDPGRPDDQITYVVEVRLPGSRRGAETGARQRLLEVVGKH
                     VSVTIVGGSLVRAEASDPMVTWRVFRESSWRNRRGLGWLASLRTQSGLADEQRTIGVAP
                     SVEEAEVRELLGRQRLGGFEFDESRHGVRKSVGPKANETDEDESPW"
     gene            complement(6562..7131)
                     /locus_tag="CP967_RS19625"
                     /old_locus_tag="CP967_19685"
     CDS             complement(6562..7131)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009337821.1"
                     /locus_tag="CP967_RS19625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19685"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_150489213.1"
                     /transl_table=11
                     /translation="MTTAPATELRTFTTLDTIRGDLLDVYAEVRAPLLHLPNYAVTAFG
                     ERIDRHSAEPGFTAVLAYAAGQPVGYAYSNTIEHGDRYWQRTSPAPAEKYTKRPATALK
                     EIGVHPAWRKTGTARRIHDALLATRDEPHVTLMVNRAAGDGKVHALYKSWGYEDIGQSQ
                     PSPASPVLTVMIHTNRRPPRRLGMAE"
     gene            complement(7128..8411)
                     /locus_tag="CP967_RS19630"
                     /old_locus_tag="CP967_19690"
     CDS             complement(7128..8411)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004000004.1"
                     /locus_tag="CP967_RS19630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19690"
                     /product="XRE family transcriptional regulator"
                     /protein_id="WP_190175097.1"
                     /transl_table=11
                     /translation="MDAIRNTVLEAWMTEHGYSSNSLADAVNRAVEQLTGRVGGLDGSS
                     VRAWKAGRVTWPKSATRTALEVITGLPAVALGFVPRGRPSPTPAPSQQEEPDMKRRTLV
                     GGIAAAAAAAATPGTASPRRIGMSDVNRLNKRFAEIIASDHRHGGQPGIEERAAALADE
                     ALNLQNAGSATQRVRSSLYASGAAFRSSAMWAAIDGRRYDVAKAHMREAQALAEMSGDQ
                     AIKFRIWSHAGTMYRHMGRPADACAANDVARNLHLTRRDPLFASLGLARQGAIHGTAQN
                     RTDTRRAFEQAQDAMLRADPADHRPVWLLAFYDQAELDSLALSAYLALGDYPTAEYHAH
                     RCLSSLRPHMVRSRAITTTRLAHALLAQGAAEAATATAMKVPADAATRHARVSRMLQEF
                     GAALRATAPRSATVQTWTEHTTTWRTAA"
     misc_feature    complement(8184..8186)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     misc_feature    complement(8199..8201)
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            8638..9084
                     /locus_tag="CP967_RS19635"
                     /old_locus_tag="CP967_19695"
     CDS             8638..9084
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763666.1"
                     /locus_tag="CP967_RS19635"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19695"
                     /product="ATP-binding protein"
                     /protein_id="WP_150489215.1"
                     /transl_table=11
                     /translation="MPILKKAVETVLASHPTYSEVFPCVPSTAETGRRLVRGVLGMWHL
                     DVLADRAELIVTELIANAARHTPCPEVRLVVGRPTATRVRVGIVDEEPSRLPELSHAGE
                     EDESGRGLFLVEAVADRWGCDLQSAGGRLRGKEVWAELHTEGDG"
     gene            9595..9774
                     /locus_tag="CP967_RS19640"
                     /old_locus_tag="CP967_19700"
     CDS             9595..9774
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LD_lanti_pre"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016825826.1"
                     /locus_tag="CP967_RS19640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19700"
                     /product="FxLD family lanthipeptide"
                     /protein_id="WP_016825826.1"
                     /sec_met_domain="LD_lanti_pre (E-value: 4.6e-13, bitscore:
                     47.5, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRSTVVPSRTEVRPQIPGASDGFDLDVSLVEIADPAGLVNLTDD
                     NCGSTCGACTTNVA"
     gene            10001..12955
                     /locus_tag="CP967_RS19645"
                     /old_locus_tag="CP967_19705"
     CDS             10001..12955
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155: Lantibiotic dehydratase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018543779.1"
                     /locus_tag="CP967_RS19645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19705"
                     /product="lantibiotic dehydratase"
                     /protein_id="WP_150491949.1"
                     /sec_met_domain="Lant_dehydr_N (E-value: 3e-200, bitscore:
                     665.2, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 4.9e-19,
                     bitscore: 67.4, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 6.6e-25, bitscore:
                     86.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLRAVWADQHIAGAVEHSSPALAMQVRVVCTTENPPLRDIRRA
                     ALSVSRYLLRAQHRATPFGLFAGVATVAFGSRARAEWGKAHVAVGRAGAEWLTAVVERL
                     ESCPELLDQLPVVVNNTVMSRGDRLIVPFQPDPNDDRMRAVEASLALTEPVRAVLAEAR
                     TPIRCGALTERLRAEFPEADTEKVHRLLAELVRRRVLITSLHAPSTETDALGYLLDQLD
                     TIDVDNLASVAETARELHAVRMGLKECATRGGRDSTAARMRALVPGLRRHPVALDLRLD
                     ARLVLPEEVAREIEHAAFTLTRVSTRPYGTAAWNAYHQRFYERYGIGTMVPLAEVVADS
                     GTGYPDGYPGSPDGSRRPRVSARDDALVRLAQGAALDRRDEVVLTDGQIDVLDVGPDEP
                     RLPPHLEVGVRVHAASLEDLQRGRFQLEVVSVSRGAGVSTGRFLDVLAPSERQALATEL
                     AGLPAADSDTVPAQLSFPPLLPESAHVTRAPQVLPTLISLQEHCAPKDTVLTPKDLAVG
                     CDGRRMYLAAPERGHRVEAVGMNALNLHTHTPPLARFLTELSRAQCAQVTAFDWGVAAA
                     MPFLPRLRYGRTVLTPARWRLEASELPGRARPRAEWDTALSEWRAQRGLPRRVLLVEND
                     RRLFLDLDEGGHRTLLLRHLDRAHQAVLTEAPEPEANGWCGGRAHEIVVPLKATRPPSW
                     PPLPVPTAARALSSAQRQTPAASSVLLAALYGDPRRQDLLLSQHLPGLIERLGNPRWWF
                     IRFRDPDQHLRVRIALPDRRTFAQTARTVSAWADDLRNAGLLADLRYATSYREMGRWGS
                     GAAWEAAEDVFRADSRAVLAQLTEPQRPTQRTLVAAHTVAIVSAFLGSAEAAMRWLTDH
                     VPPTAPASVPRPQFSEAVRLANPADDWAALREVQGGDAIVSGWAERDAALAAYRLHLPG
                     PDTQGIAVDDVLTSLLHVHFVRHVAVNFPEEEVCLYLARAAALAWTARTAKRPA"
     aSDomain        10346..10621
                     /aSDomain="Lanthipeptide_LanB_RRE"
                     /aSTool="RREfinder"
                     /database="RREFam.hmm"
                     /description="RRE-containing LanB protein in a class I
                     lanthipeptide cluster"
                     /detection="hmmscan"
                     /domain_id="rrefinder_CP967_RS19645_Lanthipeptide_LanB_RRE.
                     1"
                     /evalue="2.10E-21"
                     /identifier="RREFam001.1"
                     /label="CP967_RS19645"
                     /locus_tag="CP967_RS19645"
                     /protein_end="207"
                     /protein_start="115"
                     /score="67.4"
                     /tool="antismash"
                     /translation="VVVNNTVMSRGDRLIVPFQPDPNDDRMRAVEASLALTEPVRAVLA
                     EARTPIRCGALTERLRAEFPEADTEKVHRLLAELVRRRVLITSLHAP"
     misc_feature    11804..11806
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            12922..14217
                     /locus_tag="CP967_RS19650"
                     /old_locus_tag="CP967_19710"
     CDS             12922..14217
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140: Lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489258.1"
                     /locus_tag="CP967_RS19650"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19710"
                     /product="lanthionine synthetase C family protein"
                     /protein_id="WP_150489216.1"
                     /sec_met_domain="LANC_like (E-value: 3.8e-43, bitscore:
                     146.2, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCPHRQEAGVTGLPTLGLVDAVAVRLADPGTVPSVLQTHRQHLA
                     YGPPGIALLHIERAANGLGPWQHAHGWLAAASHGSLTSGPDSHPFYGVPAFAHALACAA
                     DHLPGSYQHALDSMDRQIGLDVRRRLDVAHRRIDAGCLPQLAEFDAIRGLTGYGAYLLR
                     RNPDSPMVRAVLDYCVRLIEPIWESGEDLPGWWTAMGPSGRPDEQFPGGHANTGMAHGI
                     AGVLVLLALAARKSTITNGHLRALHTILAWLDRWQEETGRGATWPYWITRSELRTGRCA
                     ASELRRSSWCYGTAGLARAQQLAALATGDTERQITAENALAAALFDPDQLGAMTDHGLC
                     HGFAGLTHIAVRTAADAHPSTVGRLRAAIPGLLAAICPVDNDLERAATALVSGTGAGPG
                     LLDGAAGTALALLAADTAAPPQSAWDSCLLIA"
     gene            14239..16317
                     /gene="fxlM"
                     /locus_tag="CP967_RS19655"
                     /old_locus_tag="CP967_19715"
     CDS             14239..16317
                     /GO_function="GO:0016740 - transferase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="fxlM"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PCMT"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018489259.1"
                     /locus_tag="CP967_RS19655"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19715"
                     /product="methyltransferase, FxLD system"
                     /protein_id="WP_150489217.1"
                     /sec_met_domain="Lant_dehydr_C (E-value: 1.7e-23, bitscore:
                     82.2, seeds: 35, tool: rule-based-clusters)"
                     /sec_met_domain="PCMT (E-value: 1.9e-44, bitscore: 150.5,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPPDWQQHNITFIDRESARHAIDERLGPALITAETEGQLTGWWFM
                     NKQPWPLRYLADEPSPIIESLLSDLVGDGAVVSWLPSVYEPESGAFGGPDAMDTAHGLF
                     HSDSRHLLTYQPSPDHLGRKETAVLLASAMMRGAGLDWFEQGDVWAKVSALRPPTDPAR
                     SERAAELVPAMRKLMTADAYSLCNQGGPLHAHEEWVTAFERAGAALAALACRGVLTRGL
                     RAVIAHHIIFHANRAGLVRDDQSALSDIAREAVMGTSDHTASPTESTTDADSVKGVNTD
                     TIATPTSDAARLRNALVDQLRADGSARTPGVETALRTVPRHVFVPDVPLEDAYANAPVH
                     IKYDTDGSSISCASQPGVVALMLDQLDAQQGERILELGAGTGYNAGLLAHLVGESGHVT
                     TLDVDDDLVEGARAHLSAAGTTNVEAVTRDGALGYAEGAPYDRIIATVGVHGVPHAWLQ
                     QLAPGGRLLVPQRLKGTVSRSIAYEKRDGRWMSLGSEMNTFMPLRRGIADDDRRVIPLS
                     TDGTVRLQAPAGQTIDAEALDGVLHEPRTEEWTGMTVRAMESPEWMELFLTCSLPSGLI
                     RMLFPQDAKGTLLTEDPYPSSTAAVDKGAVTYLARRLSEKKTSEGGKLWEFGVIGHGPG
                     SDELAARVAAAIRAWDLGYRGRGATFEIQPLDAPAIEQRAGLFALDTPLNRIVVEWS"
     misc_feature    14266..14280
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            16403..17527
                     /locus_tag="CP967_RS19660"
                     /old_locus_tag="CP967_19720"
     CDS             16403..17527
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003999997.1"
                     /locus_tag="CP967_RS19660"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19720"
                     /product="hypothetical protein"
                     /protein_id="WP_167535413.1"
                     /transl_table=11
                     /translation="MDPHGSTAQHFPLVARFRPACLPLPKRVRALVDLADTAMAETDQG
                     VASSVYNQAALIASDLDLPDLAREMCHQHAAAYLHACPLPGMTAIRGLEPVVNLARLQI
                     RAGRADEGRRRLLDLYGAVEAGTSVRFEGVTVPADLTATDEDRHEVRAWLWRVLLADGT
                     RTLTTEGRWAEALAHIEAHHGVGKRMLDGRQVAVLAALVVSDTAGAAALLTETMPGDPW
                     EQAVTACLTALSRRDARQPVDSHLRDLAAICLERQAEPGITVFDIRLGLTVLDAIGSAE
                     APAAHRIVEDLHRRTTDAEDGYAARENLAHPLFVAIATDRQEQDCRALVRACAIGAGTM
                     PDQLQAELRAALSASDSVIRESLARLSDPNALPL"
     gene            <17570..17815
                     /locus_tag="CP967_RS34730"
                     /old_locus_tag="CP967_19725"
                     /pseudo=""
     CDS             <17570..17815
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010473986.1"
                     /locus_tag="CP967_RS34730"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19725"
                     /product="site-specific integrase"
                     /pseudo=""
                     /transl_table=11
                     /translation="PRQRGPRYLQAAREDGMHALWHAYASVLLDAGESIKTLSEYLGHS
                     DPGFTLRTYTHLLPKAASVPQAKPMCPGCLTAPLRR"
     gene            complement(17864..18448)
                     /locus_tag="CP967_RS19670"
                     /old_locus_tag="CP967_19730"
     CDS             complement(17864..18448)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016326956.1"
                     /locus_tag="CP967_RS19670"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19730"
                     /product="hypothetical protein"
                     /protein_id="WP_150489218.1"
                     /transl_table=11
                     /translation="MHRGGGVGEGTDDLGPEPARRGRHRRGAGRGRDARPADARAPEIR
                     SGGRVGVTYRYFGAPDGATAARVPISMRPEELGGDELGMGGMFSKIKPETVAAMVLTGI
                     QGIPLHRVPPLELVVLHPDYAVVKLPMTVVDPLRDVGEESVGAAAFIWSTVPDRGGPRD
                     AFNVYQLLHEWQDFSHRLHDAGHQAYCLVWP"
     gene            18743..20050
                     /gene="hemL"
                     /locus_tag="CP967_RS19675"
                     /old_locus_tag="CP967_19735"
     CDS             18743..20050
                     /EC_number="5.4.3.8"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0042286 - glutamate-1-semialdehyde
                     2,1-aminomutase activity [Evidence IEA]"
                     /GO_process="GO:0006779 - porphyrin-containing compound
                     biosynthetic process [Evidence IEA]"
                     /NRPS_PKS="Domain: Aminotran_3 (42-365). E-value: 1.6e-74.
                     Score: 242.9. Matches aSDomain:
                     nrpspksdomains_CP967_RS19675_Aminotran_3.1"
                     /codon_start=1
                     /gene="hemL"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015609265.1"
                     /locus_tag="CP967_RS19675"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19735"
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="WP_150489219.1"
                     /sec_met_domain="Aminotran_3 (E-value: 3.1e-84, bitscore:
                     281.6, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAYSYEAPVSQSLFDRASRVTPGGVNSPVRAFRAVGGTPRFMVSG
                     TGPYLTDADGREYVDLVCSWGPMILGHSHPEVLAAVQEAVARGTSFGTPGEGEVALAEE
                     IVARVEPVEQVRLVSSGTEATMSAIRLARGFTGRAKVVKFAGCYHGHVDALLAAAGSGV
                     ATFGLPDTPGVTGAQAGDTIVLPYNDLDAVRAAFAAQPGEIACVITEASPGNMGVVPPG
                     EGFNAGLKEICAQHGALYISDEVMTGFRTSKAGWYGVDGVRPDLMTFGKVMGGGFPAAA
                     FGGRADVMAHLAPAGPVYQAGTLSGNPVATAAGLAQLRLLDDAAYAKVDAVSAEIRSLV
                     SEAFTKEGVAHTVSAASNMFSVFFTDGPVRDYEDAKKQEAFRFTAFFHSMLAQGVYLPP
                     SAFESWFVSTAHDARAVERVAAALPAAARAAAEATA"
     aSDomain        18869..19837
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP967_RS19675_Aminotran_3.1"
                     /evalue="1.60E-74"
                     /label="CP967_RS19675_Aminotran_3.1"
                     /locus_tag="CP967_RS19675"
                     /protein_end="365"
                     /protein_start="42"
                     /score="242.9"
                     /tool="antismash"
                     /translation="VSGTGPYLTDADGREYVDLVCSWGPMILGHSHPEVLAAVQEAVAR
                     GTSFGTPGEGEVALAEEIVARVEPVEQVRLVSSGTEATMSAIRLARGFTGRAKVVKFAG
                     CYHGHVDALLAAAGSGVATFGLPDTPGVTGAQAGDTIVLPYNDLDAVRAAFAAQPGEIA
                     CVITEASPGNMGVVPPGEGFNAGLKEICAQHGALYISDEVMTGFRTSKAGWYGVDGVRP
                     DLMTFGKVMGGGFPAAAFGGRADVMAHLAPAGPVYQAGTLSGNPVATAAGLAQLRLLDD
                     AAYAKVDAVSAEIRSLVSEAFTKEGVAHTVSAASNMFSVFFT"
     gene            20047..20751
                     /locus_tag="CP967_RS19680"
                     /old_locus_tag="CP967_19740"
     CDS             20047..20751
                     /EC_number="3.1.3.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1101: phosphoglycerate mutase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460418.1"
                     /locus_tag="CP967_RS19680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19740"
                     /product="histidine phosphatase family protein"
                     /protein_id="WP_150489220.1"
                     /transl_table=11
                     /translation="MSGESVSEDRGQDITVVHLMRHGEVHNPEGVLYGRRSGYHLSELG
                     RKMADRVAGHLEKRDITHVVASPLERAQETAAPVAASHGLEVAVDERLIEAANVFEGKT
                     FGVGDGALRKPDNWKHLTNPFKPSWGEPYIEQVVRMMGALDAARDAARGHEAVCVSHQL
                     PIWIVRSFVERRRLWHDPRKRQCTLASLTSFTYRGDKIVSVGYTEPARDLVPPHLRAGA
                     KPVKGKSKAFGA"
     gene            21127..22395
                     /locus_tag="CP967_RS19685"
                     /old_locus_tag="CP967_19745"
     CDS             21127..22395
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007460422.1"
                     /locus_tag="CP967_RS19685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19745"
                     /product="hypothetical protein"
                     /protein_id="WP_150489221.1"
                     /transl_table=11
                     /translation="MREINRRGLLGAGLGAAAALSIAGCDSLGPSGGDGPEAGPEKSPK
                     GEKGTQGNGSGQGAPKKNVRIIGDGSTSDTGKQPNQPAAPVPLEPGQKPPQFVIFSWDG
                     AGEVGNGLFPRFLEIAREHDAKMTFFLSGIYLLPESRKSLYRPPNNPRGASDIGYLTDG
                     HVKETLTHVGRAWLDGHEIGTHFNGHFCAGSGSVANWTPAQWQSEIDQAVSFVTQWRTN
                     SGWSDIDPLPFDYRKELIGGRTPCLLGQDNLLPTAKQLGWRYDASSPGGRQVWPEKRRG
                     IWDLPLQGVPFPGHSFEVLSMDYNILANQSKNSTKGVPARYPGWRTQAVGAYLAGFDRA
                     YETNRAPFYVGNHFEEWNGGIYMDAVEEVIKRIAGKPDVRLVSFRQFVDWLDVQDPAVL
                     AKLRTLEVGESPAGGWNTFFKQA"
     misc_feature    22448..22463
                     /note="TFBS match to CRP, Cyclic AMP receptor protein,
                     confidence: medium, score: 16.6"
                     /tool="antismash"
     gene            22463..23068
                     /locus_tag="CP967_RS19690"
                     /old_locus_tag="CP967_19750"
     CDS             22463..23068
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1241: lipoprotein
                     dsbF"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018961611.1"
                     /locus_tag="CP967_RS19690"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19750"
                     /product="TlpA disulfide reductase family protein"
                     /protein_id="WP_150489222.1"
                     /transl_table=11
                     /translation="MSSGRVTRRRSTLLAATAVAGALTLSACSDDGTITTGGGDTNFVT
                     GNSGIATVPKGERTAAPELVGTTLDDKPLDVADYKGKVVVLNVWGSWCAPCRAEAQHFA
                     KVSKETADQDVQFIGLNTRDPEKSLAISFEEDHGVTYPSLYDPRGKLILRFPKGTLNLQ
                     TIPSTVVLDRDGKIAARKLGGLDAEKLHEMIDPLIAEK"
     gene            23072..23857
                     /locus_tag="CP967_RS19695"
                     /old_locus_tag="CP967_19755"
     CDS             23072..23857
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046594.1"
                     /locus_tag="CP967_RS19695"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19755"
                     /product="cytochrome c biogenesis protein CcdA"
                     /protein_id="WP_150489223.1"
                     /transl_table=11
                     /translation="MLQLAARGGELAALTGDNETVLSGALLIALPIALLAGLVSFFSPC
                     VLPLVPGYLSYVTGVSGTDLADARRGRMVAGASLFVLGFTAVFVSSGALFGYFGQNVME
                     HSDVLTKVLGVLMILMGVFFMGLMPWMTQREFRIHRKPVTGLLGAPVLGALFGIGWTPC
                     LGPTLSSVTALAMQQGTAGRGAVLSVAYCVGLGLPFVLAAVAFRKALGAFGWVKRHYAW
                     VMRIGGGMMIVTGILLLTGAWDTLIQEMRVWSDGFTVGI"
     gene            23863..25569
                     /locus_tag="CP967_RS19700"
                     /old_locus_tag="CP967_19760"
     CDS             23863..25569
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_process="GO:0017004 - cytochrome complex assembly
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015577608.1"
                     /locus_tag="CP967_RS19700"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_19760"
                     /product="cytochrome c biogenesis protein ResB"
                     /protein_id="WP_150489224.1"
                     /transl_table=11
                     /translation="MSNLNTTDEREIGTAGEQLSTAPREESATTVPALGVIGWARWFWR
                     QLTSMRVALILLFLLSLGAIPGSLIPQNSVDEMKVEAFKGDHTTLTPLYEKLQFFDVYS
                     SVWFSAIYILLFISLIGCIVPRTGQFVGQLRSRPPGAPKKLTRLPAYTTWRTEAEPEQV
                     REAALAVLRKRRFRSHTAGDAVAAEKGYLREAGNLLFHIALIVMLIAFGWGQLFKFEGG
                     KLVLEGDGFSNTRTQYDDFRPGTLFTDEDLVPFSFGLDAFEGTYERTGPQRGTPRTFEA
                     HVTYSEGVDGKPKKKVVQVNKPLVVDGTKVYLNAHGYAPVVSVKDGRGKEVYRNAVPLL
                     PQDDNITSTGAIKVLDGYRDANGEKTQLGFQAFFVPTFAGNGKGTMFSQFPALDYPVLA
                     LNGFHGSLGVDSGLPQNVYQLDPSKMEMFKDGSGNQLKQRLRPGETMTLPDGAGSITFE
                     GVEEWASFQISRQPAAGWALTGAVAAIAGLAGSLFIQRRRVWVRAVPGPDGVTVVEMAG
                     LGRSESAKLPEELADLAVELHTQAPTAPEPESGTGTESDQPSEEPAEGAEK"
ORIGIN
        1 ggccagcccg gcccagtcgg cttccgggcc ggccgccgcg cgttccagcg cctcgtggat
       61 gcggtggcgg aggatgaccc acttgggccc gaccccgaca cgggtggcga agagccgctg
      121 gagcgagcgc gccgacatcc cggcggtccg cgcgagcgtg tccacccgga gcagggcgcg
      181 gtccgtgcgg acgagctcgg cgagcgccgt cacctgggcc gtacgcgggt cgaaggcggg
      241 caccagaggc agcagatacg cgtcgagcgc ggcgacgcgg gcgtcctcgc cgggcgggcc
      301 cagcacctcc ccggacggtg gggcgggcag cagccctgcc gccgggacat accgcccggt
      361 ccactccgac accggccgct ccggcgcgaa cggccagaaa cccccgggcc ggaacttcac
      421 cccgcacacc ctcccccggc ccgtcaggcg ccgggtgaac agcccccgca cgatgccgtg
      481 gacctcggcg cggtcggcgg gcccggggcc gccgggctcc tcgtcccgct ggaagaccag
      541 atggacggac gggtgcggca cgacccgcga ggtgtagggc tcggtgaggt cccagtcgat
      601 cagccagtag tgctccacga agggtcgcag ggcgggggcc gggtcacggc ggcggaaacg
      661 cacccggctg aacagagcgg gtgcgtcgac gatgccccgt gtgtcacgtc gggatccggc
      721 catggacgga tcctaagggc tgttccgccg gggccgcggg gtcttcgggg gctgctccgc
      781 gggccgtgcg ggggctgtcg cgtttcttca agacggccgg gcctccccgg gggcatcgtc
      841 ggccgtatga agaagatcag tgaactcctg gagaccgccg cggcgctgac ctgccccgtc
      901 gtgcggggca tcgacgacgc ccgtctggac gcccccacac cgtgcgccga gtacgacgta
      961 cgcgccctgc tgaaccacct cttcctcgtc gtcaccaact tccgggcgct ggcggcccgc
     1021 gaggaggccg acttcagcac cacaccggac gtcgtcacgg gcgactggcg cggccgcttc
     1081 gagaaggaga cggcgtcgct ggtggcggcg tgggacgcct ccggcgcgga ggacggcgtg
     1141 gccgggagga tgaacctgcc cgcccggacg gtgggcctca tggtgctggg ggacctggtc
     1201 gtacacggct gggacctggc gcgggcgacc ggccgttcct tcgacgccgg ccccgccctg
     1261 gtggaggtgc tggagccggg cctggccgga atggccccgc aggcccgctc gatgaacgtg
     1321 ttcggcgagc ccttccccct gcccgccggc gccccggcct tcgaccgggt gctcgccctg
     1381 accggccgcg acccgggatg gagcccggcg ggggcatgag gacgggcact ccgccggacg
     1441 gcggcccggc cgtccggcgg agtgcccacc gccctggtca ggaggcgacg aagcgggcga
     1501 tctcgccgag cacgagcgtg tccgcgagga acccgatgtg ggtctggcag agcaccgggt
     1561 tgttcgtcgc accgctcagc cgggtgctgg tgtacggcag gatgatgccg tcgcacgccg
     1621 agtaccagct ggcgtacctg gtgctgcccg gcgtctcgtc acccgaggtg atctgcgcga
     1681 tgaaggagga gcccgggtac atctgctggc aggtcgtgta gatcaggcag gcgccggcga
     1741 aggtggtccc gtggttcgcg cccgcgatcg aggcgaggtg gctgacgctg gagtggccgc
     1801 ccagcacctt caggtagtac tggctgacca ggccgcccat cgagtggttg acgatcgcca
     1861 ccttgctcgc accggtccga gacttcacgt tgtcgacgaa ggaggcgagt ccccgcgcgt
     1921 tgccgacgtt gtcgccgtac gagtcgtact cgtaggcgaa gaggttcgaa ccggaccagc
     1981 cgttgagccg gaagacgctc atggcggtga cccagttgga cgcgctcccc gtgtagccgt
     2041 ggacgaagac gaccggtgtg ccggtggaca gcggcgcggc ggccgaggcg gaggaggaga
     2101 cggaggaagc ggccgggacc tcggccgccc cggccgccga cgccggggag aacagggtga
     2161 aagcgatcgc ggcggaggcg agggcgccga gaagccggcg cggtgaacga cgacgcatgg
     2221 gactctcctg acgaggaggc gggtgcctga cccgaccagg gtcgtgggac accgcacggg
     2281 cgccatcggt gaaatcaccg gcggcgcccc ggccaccgcc tcaccacgcc tccgtcccct
     2341 ccgccgcgtc cggaccgggc cccggcttcc tgcggcccgg accgccgagc gccgtccgca
     2401 gccgcgtcgc ggccagcggg agcacgagca cggagatcat cgcggcgccg acgagcgagg
     2461 cggcccggtc ggtgcccagc agttcctggt ccaccccgat ggccgtgatc gcgacgacca
     2521 gcggcagaca cgtcgaggcg aacagcgcga gggcggcccg gtcgccccgg cccaggtccc
     2581 gcggggcgag caggtacacc ggcccgccgc gcaccagcac gaagagcagc aggaagaccg
     2641 gcagcagcag cagggcgacc ggatcgtgca gcaacgcgtc cagatcgaac tcgatgccgg
     2701 tgacgacgta gaacagcggt acgaggaaac cgaaccccat ggcctccacc cttcccagca
     2761 cctccgcact gctcgccggg gcggcccggt ggagtaccag gcgggtgagg acaccggcgg
     2821 cgaaggctcc cagcagcacg tccaggccga agacctcggc cagccccagc atgcaggcca
     2881 gcagcagcat gacgaaccgg accgcgaact ggccgctgct gtgcagggtc cgttcggtga
     2941 tccggccgaa ccaggccgga cgcggccgga gcgcccagaa gacggccagg acggtgaccg
     3001 ccccgaacgc ggccagcaga gccgccgact cggccggccg gcgcccgctg agcagcagcg
     3061 ccatggcgac gacggggccg aactccccga ccgcgccgaa cgccgagacc accgtgccga
     3121 agcggccccg cagctcaccg ctgtcccgca gcatcggcag gatcgtgccg agcgccgtac
     3181 tggtcagcgc ggtcccgacg acgaacgcct cgaacaccgc accgccgctg atcaggaaac
     3241 ccagtccgat accgagggcg agtgagagcg gccaggccca cagcgaacgg cgcagggtgt
     3301 cgccgcggac ggcggcgaac tcgatctcgt aaccggccag gaagatcagc atggacagcc
     3361 cgagatcggc gagcgtgtcg atgacctcgt cgggatccgc ccagccgagg acctgcgggc
     3421 cgatgaggac gccgagcacg atctcgaaga cgaccagcgg tacgcggacc cggctcccgg
     3481 tggcatggac gaggagcggc gccagtgcgg ctgccgccag gatcaggacg agggtgccgg
     3541 gagaggccat cgtggaccgc cggtcgccgt gtcagggggt gacggtcgcg aagccggggc
     3601 ccggggcttt cggaacacgc cccaggagta cggccggctc cgcgggcccg gaccgtgtgg
     3661 tgctggacat gggcgtctcc ctcgccggcg gtatgcgaag accggtggcc cgacggcgca
     3721 cacggccacc gccactctca cccgtgcggg cggccgggac gaccaggcgt acgccgtcgg
     3781 gaggaacgcc gccggatccc gccgccggtt tccgccgccg gaccctgccg ccggtttccg
     3841 ccgctggtga gagcggggcg cgcgcgacgg cgccgcggca cggcgttcca cggcggcccc
     3901 tggacgtacg tccgccggga aggtcgggag tgtcctggaa tgcgcaggcg gtcgagccga
     3961 cgtttactgg cggttcccgt accggcccga cctgttccgg aggttcccat ggccaccctg
     4021 accgtctgga agttcgacac gcccgagggg gcgtcggacg ccgaggacac cctgctccag
     4081 ctgcagaaac aggaactgat caaggtcctg gacgcggcgg tcgccacctg gcccgaaggg
     4141 gagaagaagc cgaggaccaa gcagctccac gacctgaccg gcgcgggcgc gctctcgggc
     4201 accttctggg ggatgctctt cggcctgatc ttcttcatgc ccctgctcgg tgccgcgatc
     4261 ggagccgcgg ccggggcgct gggcggcagg atggccgaca tcggcatcga cgacgacttc
     4321 atcgactcgg tcaagacgca ggtcacgccc gggacgtcgg cgctgttcct gctctcccag
     4381 gacgccgtgg tcgaacgcgt gcgggaggcg ttccccagcg gtcacgccca gctgctccag
     4441 tcgaacctgg actccgccca ggaggccagg ctgcgcgagg tcttcgcgga ctgagccggg
     4501 accggaggtc ttctgcgaga ggggccgggg ccaccggtcc cgtgccccgt cgcggctccc
     4561 ggacaggcgt gcgcccggga gccgcgcccg tgcgccgacc gcccgtgccg ttgccgtccg
     4621 tgccgttgcc gtccgtgggc cgaccgtccg tgccgctgcc gtccgtgccg ggcggccgcc
     4681 gagggcggtg aatcccggga ccccgggctc agggccagac caggcagtac gcctgatgcc
     4741 ccgcatcgtg cagccggtgg gagaagtcct gccactcgtg cagcgattgg gtgcgggagg
     4801 gcactgacct gggagttctt ctgagagtgt gcgttgacct gggaaaactc ctctcggtag
     4861 tgctcacgga tcaacgccgt ttcccaggct catgtgccct ggatgctcac tttttaccga
     4921 cctctcttgc ttggaacggg tcagtgcgag atcggcgcct gtggtgactg atgttctgct
     4981 tgtcgcgcct catggctgct ccggacagcg gctctgaccg tcgctcactg cgtatgtcga
     5041 gacctctgcc gagcgcaccg acattacggg atcgggtccg ccatgttccc ggacgcgcac
     5101 cgggtcccat aggtagagga catcgccctc cgtgctgaaa gcgagcagcg gacgatcggt
     5161 cgggagtggt ccattgtgca cggagagctt gcctttgagc ggctgtacgc agatccgcac
     5221 tccctggatg ccgaagtagg aatccggtgc agtcgcgttc actacgtcac gggccgcgcg
     5281 gtgggccgca tcggaggtcc ggctcatgaa cgcgactcct ccagtgacga cgagcacgac
     5341 tgcggcaaca gtggacacga cgctcaccat gctcttctcc caggcccagt ggaaaaggcg
     5401 agcccagccg tagagagcca gaggcggcag gagtagcccc aagcagccga gagtagggag
     5461 cagtgcagct gcaccggtcc aatagacggg ggcggagacc gagtcagcgg ggattccgaa
     5521 agcatcctcc acgtacagga actgcaagaa agagccgacg aacggcagga cccacggcag
     5581 gggcaggacg agcacggtaa gcaggccgac ggcgtgcctg ctgatccagg tctggcgaac
     5641 ggcgaaccag cagcctcaag gtacagacca caacggggga aggcccggcc gagctaccag
     5701 ggactttcgt cctcatccgt ctcattggcc ttgggcccca cgcttttgcg cacgccgtgg
     5761 cgcgactcat caaactcgaa gcctccgagc cgctgtcgcc caagtagctc gcggacctcc
     5821 gcttcttcga cggatggagc aacaccgatg gtgcgctgct cgtcggcgag ccctgactgg
     5881 gtacgcagcg aggccaacca gccgaggccc cgcctgtttc gccagctgga ctcccgaaag
     5941 acgcgccaag tcaccatcgg gtcagacgcc tcggcacgga cgagagagcc tcccacgatg
     6001 gttacggaca cgtgcttgcc cacaacctcc agcagacgct ggcgggcacc ggtttcagcg
     6061 cccctgcgcg agccggggag ccgcacctct acgacgtatg taatttggtc gtccggtcgt
     6121 ccgggatctt cctgctcatc ggccggtcgg atggcccaac cttgttgctc acacaacccc
     6181 ttggcgagca actgatcacg cccacgcttc ggggcccgaa agaccagatc tacccgctcg
     6241 tcgaaccccg cggtcggcag agggacttcc aactcgccga cagctgcgct gatcggagac
     6301 ccgccggacg gagaatcgtc catcgtcctg cgtggaccgg gaacccccca ccgtgtctcc
     6361 gtcctcgtcc tccgttcact attcgacgac gtgagacggc gaatgaacag cgtgtcgaac
     6421 cgcattgctt tgacattccc tttgtggtcg gcgctatgcc ggtggatggg gcgggcgtgc
     6481 atggagccat ggccgtccca taacccaagt gcgattacgg tcgcacggag cactgacaat
     6541 gccgcccgac actgccgccg cctactccgc cattcccaac ctccgcggtg gtcgacggtt
     6601 ggtgtggatc atgacggtaa gcacaggtga ggctggcgat ggctggctct gcccgatgtc
     6661 ctcgtaaccc cacgacttgt agagcgcgtg gacctttccg tcgccggcgg cccggttgac
     6721 catgagcgtg acgtgcggct cgtcgcgggt ggcgaggagg gcgtcgtgga tgcggcgggc
     6781 cgtgccggtc ttgcgccagg ccgggtgcac gccgatctcc ttcagagccg tggccgggcg
     6841 cttcgtgtac ttctccgccg gcgccgggct ggtgcgctgc cagtagcggt ccccgtgctc
     6901 gatggtgttg ctgtacgcgt agccgaccgg ttggccggcc gcgtacgcga ggacggccgt
     6961 aaaacctggt tcggcggagt gccggtcgat gcgttcgccg aatgcggtca ccgcgtagtt
     7021 cggcaggtgg agcaacgggg cgcgtacctc ggcgtacacg tcgaggaggt cgccgcggat
     7081 ggtgtccaag gtggtgaagg tgcgcagctc ggtggcgggt gccgtggtca tgcggccgtc
     7141 ctccaggtgg tggtgtgctc ggtccaggtc tggacggtgg cgcttcgcgg ggcggtcgcg
     7201 cggagcgcgg ccccgaactc ttggagcatg cgagacacgc gggcgtggcg ggtggcggcg
     7261 tctgcgggga ccttcatcgc ggtggctgtt gcggcctcgg cggcgccctg ggcgagcagg
     7321 gcgtgtgcga gacgggtcgt ggtgatggcc cgggacctga ccatgtgggg ccggagcgag
     7381 gacaggcagc ggtgggcgtg gtactcggcg gttgggtagt cgccgagcgc caggtacgca
     7441 gagagggcca aggagtccag ttcggcctgg tcgtagaagg cgagcaacca gaccggccgg
     7501 tggtcggctg gatcggcgcg cagcatggcg tcctgcgcct gctcgaatgc gcgacgtgta
     7561 tcggtccggt tctgggccgt accgtggatg gcgccttggc gggccaggcc gagggacgcg
     7621 aacagcgggt cgcgacgggt gaggtgcagg ttgcgggcga catcgttggc ggcgcatgcg
     7681 tcggcggggc gacccatgtg gcggtacatg gtgcccgcgt gactccagat acggaacttg
     7741 attgcttggt cccccgacat ctcggcgagg gcctgggctt cgcgcatgtg cgccttcgcg
     7801 acgtcgtagc gccggccgtc gatggcggcc cacatcgcag acgagcggaa tgcggctccg
     7861 gaggcgtaga gactgctgcg aacccgctgc gtggcactgc cggcgttctg gaggttgagc
     7921 gcctcgtcgg cgagcgcggc ggcccgctcc tcgatgccag gttgcccgcc gtggcggtgg
     7981 tcgctggcga tgatctcggc gaagcgcttg ttcagccggt tgacgtcgct catgccgatt
     8041 cggcgcggtg acgcggtccc tggggttgct gctgcggcag ccgcagctgc gatgccgccg
     8101 acgagggtac ggcgcttcat gtcgggctcc tcctgctgcg atggcgctgg ggtgggcgaa
     8161 ggccggcccc gtggcacgaa ccctaaggcg acggcgggta atccggtgat gacctcaagt
     8221 gcggtacgtg ttgctgactt cggccaggtg actcggcccg ctttccacgc ccggaccgat
     8281 gacccgtcga gcccgcctac gcgtcccgtc agctgttcaa cagctctgtt cacggcgtcg
     8341 gccaggctgt ttgagctgta tccgtgctcg gtcatccacg cctcaaggac ggtgttgcgg
     8401 atcgcgtcca tgcgggcacg gtagcccgcg cgctccctgc ccaccaggta aagagcaggt
     8461 caaaacgtcc taggacagcc cgccggacgg gcacctgaac gccctaaccg gccctccagg
     8521 caacggagtt atctgggtgt cagccactcc ccgcgagcgg ctgttgacgg ctcggtccgc
     8581 ccctgaaaag ccacaagggg tggagcgagc gccgagacga cacgaaggct ccatcccatg
     8641 ccgattctga agaaagcggt tgagacggtc ctcgccagcc accccacgta cagcgaggtc
     8701 ttcccgtgcg tgccgtccac ggccgagacc ggacgcaggc tcgtccgggg ggttctcggg
     8761 atgtggcacc tcgatgtcct cgctgaccgc gccgagctga tcgtcactga gctgatcgcg
     8821 aatgccgcca ggcatacccc ttgccccgag gtccgtctcg ttgtcgggcg gccaactgcg
     8881 acacgggtac gcgtagggat cgtggacgag gaaccgtcgc gtctgccgga gctgagccac
     8941 gcgggcgagg aggacgaatc aggtcgcggg ctgttcctcg tcgaagctgt ggccgaccgc
     9001 tggggctgtg accttcagag tgcaggcgga cgtctgcggg gcaaagaggt ctgggccgaa
     9061 ctccataccg agggcgacgg gtgagggccc ggacgcgatg ccctcgcttc ttctgggccc
     9121 tgcccgcccg ccctttcagc tctgggccga caccgccaga taccaggctg ccggatcggc
     9181 cgtatcggtc agctgagggg aggtccgttc ctcgatgaat tcatcgtgga tcaccggtga
     9241 ctgccggctc ggctgcgaac ggaccggagt gcgggtgatc tggctcggcc cggttcagcg
     9301 ggacgggcag cacgcccctt ctacgcatgt gagctgtgcc ttgatcgtct caaggcacag
     9361 gccctcacct acctcatggg gcattgacgg gcctccgctc gatccgcccc tcgtacatga
     9421 cttcccagcg tgagcgggcg gtccggccag cgctttctgt gcgggccgcg ccccctcgtg
     9481 ccgggcggcc aggagctggt ccgagggcca gccgttcggc atcgctcttc tggcggctcc
     9541 tggtgggcat tccagcccag ctcagtaaca accaacgatg aagaggagtg cagcatgacg
     9601 cgcagcaccg tggtgcccag ccgtaccgaa gtacgaccgc agattccggg tgcatcagac
     9661 ggcttcgacc tggatgtctc gctcgtggag atcgccgacc cggcaggtct ggtcaacctg
     9721 accgacgaca actgcggttc cacctgcggc gcctgcacca ccaacgtcgc ctgacgcctg
     9781 aattgaagcc ccaggtcacc ttcggtctgg tgccgtcgcg ctcccgcgcg gcggcaccag
     9841 ccgcccatac cttcgcccat ggaggtcatc gatggttgct caacccacag tgttccgggc
     9901 cggttccacc gctctcgtgc gcgccgtggc ccgactgttt ctgccggttc ctccgtgccc
     9961 tgacccggat gaccactctt ccgacggctc ctctgcctgc gtgacgtggc ttcgcgcggt
    10021 ctgggcggac cagcacatcg ccggcgccgt ggagcactcc agcccagcct tggccatgca
    10081 ggtgcgggtc gtgtgtacga ccgagaatcc tccccttcga gacatacggc gcgcggcgct
    10141 gtcggtgtcc cgttaccttc tgcgggccca gcaccgggcc acgcccttcg gcctgttcgc
    10201 cggagtggct actgtggctt tcggctcgcg ggcacgtgcg gagtggggca aggctcacgt
    10261 ggctgtgggc cgcgcgggtg cggagtggct caccgctgtg gtcgaacggc tcgagtcctg
    10321 cccggaactc ctcgaccagc tgcccgtcgt cgtcaacaac acggtgatga gccgggggga
    10381 ccggctcatc gtgccgttcc aacccgatcc gaatgacgac cggatgcgcg cggtcgaggc
    10441 atccctggct ctgacagagc cggtgcgtgc ggtcctcgcc gaggcccgga cgccgattcg
    10501 ctgcggagct ctcacggaga ggctccgggc ggagttcccc gaggccgata cggagaaggt
    10561 gcaccgtctg cttgcggagc tggtccggag gcgagtgctc atcacgagcc tgcacgctcc
    10621 aagtaccgag accgacgccc tcgggtatct gctcgaccaa ctcgacacga tcgacgtcga
    10681 caaccttgcg tcggtagcgg agacggcacg cgagctgcac gcggtccgaa tgggcttgaa
    10741 ggagtgcgcc acgcgcggcg gccgggacag caccgcagcg cggatgcggg ccctcgtgcc
    10801 cggcctgcgg cgacaccctg ttgcgcttga cctgcggttg gatgcgcggc tcgtcctacc
    10861 ggaggaagtg gctcgggaga tcgagcacgc cgccttcacc ctgacccggg tgagcacccg
    10921 cccgtacggg acagccgcgt ggaacgccta ccaccagcgc ttctacgagc ggtacggcat
    10981 cggcacgatg gtcccgctcg cggaggtcgt cgcggacagc gggactggct accccgacgg
    11041 ctacccgggc agtcctgacg gttcgcgtcg gccccgcgtc tccgctcggg atgacgccct
    11101 cgtacgcctg gcgcagggtg ctgcgctcga ccgccgcgac gaggtcgtac tcactgacgg
    11161 acagatcgac gtcctggacg tggggcccga cgagccacga ctgccgccgc acctggaggt
    11221 aggggtgcga gtgcacgccg ccagtctgga ggacttgcag cgcggacgat tccagctgga
    11281 ggtcgtgagc gtgtcgcgcg gggccggcgt ctcgacaggc cggttcctcg acgtattggc
    11341 gccctccgag cgtcaggccc tggccacgga gctggccggt cttccggctg cggacagcga
    11401 caccgtgccc gcccagctct ccttcccgcc gctgctcccg gagagcgctc atgtcacccg
    11461 cgccccgcag gtcctgccta ccttgatcag cctccaagag cactgcgcac cgaaagacac
    11521 cgttctcacc ccgaaggacc tggccgtggg gtgcgatggc cgccgcatgt acctggccgc
    11581 tccggaacgg gggcaccgcg tcgaggccgt cggcatgaac gcgctgaacc tgcacacgca
    11641 cactccgccg ttggcacgct tcctcactga actgtcccgt gcccagtgcg cgcaggtcac
    11701 cgcctttgac tggggcgtcg cagcagcgat gccgttcctg ccgcgcctgc ggtacgggcg
    11761 tacggtgctg accccggcgc gctggcgtct ggaggcgtcc gaattacccg gccgtgctcg
    11821 tcctcgtgct gagtgggaca ccgcgctctc cgaatggcgg gcacagcggg gattgcctcg
    11881 ccgcgtgctt cttgtggaaa acgaccggcg tctcttcctc gacctcgacg aaggcggcca
    11941 ccggacgctc ctgctccgac acctcgaccg cgctcaccag gccgtgctca ctgaggcccc
    12001 ggaaccagaa gcgaacggct ggtgcggcgg gcgagcccac gagatcgtgg tgccgctcaa
    12061 agcgacccgg ccgccgtcct ggccgcccct gcctgttccc actgcggctc gcgccctctc
    12121 gtcggcccaa cggcagactc ccgctgcttc atcggtgttg ctcgccgcct tgtacggaga
    12181 tccacgccgc caggacctcc tgctttccca acacctcccc ggactcatcg aacggctggg
    12241 caacccgcgg tggtggttca tccgcttccg tgacccggac cagcacctcc gcgtccgcat
    12301 cgctctccct gaccgtagaa ctttcgctca gacggcgcgc accgtgagcg cgtgggccga
    12361 cgacctgcgc aacgccggcc tgctggcaga cctgcgctat gccacctctt atcgagaaat
    12421 gggccgttgg ggctccggcg ctgcctggga ggcggccgag gatgtgtttc gggcagactc
    12481 gcgcgccgtt ctggcccagc tcacagagcc gcagaggccg acgcaacgca cgctggtggc
    12541 ggcccacacc gtcgccatcg tctccgcgtt cctcggcagt gccgaggccg cgatgcgctg
    12601 gctgaccgac cacgtcccgc cgacggcgcc tgcgtccgtt ccccgcccgc agttcagcga
    12661 ggccgtacgg ctcgcgaacc cagccgacga ctgggccgcc ctgcgtgagg tccagggcgg
    12721 agacgccatc gtgtcgggtt gggcagagcg cgatgcggca ctcgccgcgt accggttgca
    12781 ccttcccggc ccggacaccc agggcatcgc cgtcgatgac gtcctgacct ctcttctgca
    12841 cgtccacttc gtgcggcacg tcgcggtgaa cttccccgag gaagaggtgt gcctctacct
    12901 ggctcgcgct gctgctctgg cgtggactgc ccgcaccgcc aagaggccgg cgtgaccggg
    12961 ctcccgacgc tcggcctggt cgatgccgtt gctgtgaggc tcgccgaccc cggcacggtg
    13021 ccttccgttc tccagacaca tcggcaacat ctcgcctacg gcccgcccgg gatcgcgctt
    13081 ctccacatcg agcgggccgc gaacggcctc ggaccgtggc agcatgcgca cggctggctc
    13141 gctgctgcgt cccacggatc cctcacgagt ggacccgaca gccacccctt ctacggcgtg
    13201 cccgccttcg cccacgccct tgcctgcgcc gccgaccatc ttcctggctc ctaccagcac
    13261 gccttggact cgatggaccg gcagatcggg ctcgacgtca gacgccgtct cgacgtagcg
    13321 catcgccgca tcgatgccgg atgccttccg caactggccg agttcgacgc catccggggc
    13381 ctgaccggat acggggctta ccttctacgc cggaacccag acagtcctat ggtgcgcgct
    13441 gtcctcgact actgcgtgcg ccttatcgaa ccgatctggg aatctggcga ggaccttccg
    13501 ggttggtgga ctgcgatggg gccctcgggc agaccggacg aacaattccc cggtggacat
    13561 gccaacaccg gcatggccca cggcatcgcc ggagtgctcg tgcttctggc cctcgccgcc
    13621 cggaagagca ccattacgaa cgggcacctc agagcgctgc acaccatcct ggcctggctc
    13681 gaccgctggc aggaggagac aggccgagga gcaacctggc cgtactggat cacccggagc
    13741 gagctacgta ccggtcgctg cgccgcgtcc gaactccggc gttcgtcatg gtgttacgga
    13801 accgccggcc tcgcccgcgc tcagcaactc gccgcgctcg ctaccggtga caccgaacgc
    13861 cagatcacgg cggagaatgc gctcgccgcc gccctcttcg acccggacca gctcggagcc
    13921 atgacggacc acggcctgtg ccacggcttc gccggcctca cccacatcgc cgtccgcacg
    13981 gccgcagacg cccatccctc aaccgtcggc cgactccgag ccgcgatccc gggtcttctg
    14041 gccgcgatct gcccggtgga caacgacctc gaacgcgcgg ccacggcact tgtcagtggc
    14101 accggagcgg ggcccggcct gctcgatgga gccgccggaa cagccctggc tcttctcgct
    14161 gccgataccg ccgcaccgcc ccagtccgcc tgggattcct gcctgctcat tgcctgattc
    14221 accgaccgaa ggacttcgat gccccctgac tggcagcagc acaacatcac cttcatcgat
    14281 cgcgagagcg cccggcacgc catcgacgaa cgcctcgggc ccgccctgat cacagccgag
    14341 accgaggggc agctcaccgg ctggtggttc atgaacaagc agccctggcc gctgcggtac
    14401 ctcgccgacg agccctcccc gatcattgag tcgctgctga gcgatctcgt gggtgacggg
    14461 gcggtcgtgt catggctgcc ctctgtctac gagcccgagt ccggggcatt tggcggtccg
    14521 gacgctatgg acacggccca cggactgttc cacagcgact cccgccacct gctcacctac
    14581 cagccgagcc cggaccactt ggggcgcaag gagactgcgg tcctgctggc gagcgccatg
    14641 atgcgcggcg ccggactcga ctggttcgag cagggcgacg tatgggcgaa ggtctcggct
    14701 cttcggccgc ccaccgaccc agcgcgctcc gagagagccg ctgaattggt tccggcgatg
    14761 cggaagctca tgaccgctga cgcctacagc ctctgtaacc agggtggtcc actccacgca
    14821 cacgaggagt gggtgaccgc cttcgaacgg gccggtgccg cgctcgccgc gctcgcctgc
    14881 cgcggcgtcc tcacacgcgg cctgcgagcc gtcatagccc accacatcat cttccacgcc
    14941 aaccgcgccg gtctcgtcag ggacgaccag agcgctctgt ccgacattgc acgagaggca
    15001 gtcatgggaa cgagtgacca caccgcgtcg ccgaccgagt cgacgaccga cgccgatagc
    15061 gtgaaagggg tgaacaccga cacgatcgcc actccgacat ccgatgccgc gcgcctccgt
    15121 aacgccctgg tggaccagct ccgggctgac ggaagcgccc gcactcccgg cgtggagacc
    15181 gcgttgcgga ccgtgccccg tcacgtgttc gtgcccgatg tgccgctcga agacgcatac
    15241 gccaacgcgc cggtgcacat caagtacgac accgacggca gctcgatctc ctgcgcctcc
    15301 cagccgggcg tggtcgccct catgctggac cagctcgacg cccagcaagg cgagcgcatc
    15361 ctcgaacttg gcgcaggcac cggttacaac gccggcctgc tcgcccatct ggtcggtgag
    15421 agcgggcacg tcaccacgct cgatgtcgac gacgacctcg tagagggcgc ccgcgcgcat
    15481 ctctccgccg ccggaaccac caacgttgag gcggtcaccc gagacggggc cctcggctac
    15541 gcggaaggtg cgccgtacga ccgaatcatc gccaccgtag gcgtgcacgg cgtgccgcac
    15601 gcctggttgc agcagcttgc tcccgggggc cggcttctcg tcccgcagcg cctcaagggc
    15661 acggtgtccc ggtccatcgc ctatgagaag cgcgatggcc ggtggatgtc cctcggtagc
    15721 gagatgaaca ccttcatgcc gctcaggcgg ggcatcgccg acgacgaccg ccgggtgatc
    15781 ccgctcagca cggacggaac cgtacggctc caggcccccg ccgggcagac catcgacgcc
    15841 gaggccctcg acggcgtcct gcacgagccg cgcaccgagg agtggacggg catgacggtc
    15901 cgcgccatgg agtcgccgga gtggatggaa ctgttcctca cctgttccct tccctccggc
    15961 ctgatccgga tgctcttccc gcaagacgcc aagggcactt tgctcaccga ggacccctac
    16021 ccctcctcga ccgcagccgt cgacaaaggc gccgtcacct acctcgcacg gcgcctgtcg
    16081 gagaagaaga cctccgaggg cggcaagctg tgggagttcg gggtcatcgg ccacggtccc
    16141 ggcagcgatg aactggccgc aagggtcgct gcggccatcc gcgcgtggga tctggggtac
    16201 cggggccgtg gagccacgtt cgagatccag cctctcgatg cccccgcgat cgagcagcga
    16261 gccggcctct tcgcgctcga caccccgctg aaccgcatcg tcgtcgaatg gagttgacac
    16321 ttcacgcgta gtgggcggtg gccgccggcg cgcaaccggc ggccaccgtg gcttacccgt
    16381 cttcacacac ctgggggagt ccatggaccc gcacggatcc acagctcagc actttccgct
    16441 cgtcgcccga ttccggcccg cctgccttcc cctgccgaag cgcgtgcgcg cgctcgtcga
    16501 cctggccgac accgcgatgg cggagaccga tcagggggtg gcgtcctccg tctacaacca
    16561 ggctgcgctc atcgcctccg atctcgacct tcccgacctc gcacgcgaga tgtgtcacca
    16621 gcatgccgcc gcctacctcc acgcctgccc cctacccggc atgaccgcga tccgggggct
    16681 ggagcccgtc gtcaacctcg cccgcctcca gatccgcgcc ggccgcgcag atgagggccg
    16741 tcggcgactg ctcgacctct atggggccgt cgaggcaggc acgtctgttc ggttcgaggg
    16801 cgtcaccgtg cccgcggacc tcactgcgac ggacgaagac cgccacgagg ttcgcgcgtg
    16861 gctgtggcgc gtgctcctcg ccgacggcac gcgcactctc accaccgagg gacgttgggc
    16921 cgaggccctg gcacacatcg aagctcacca tggcgtcggg aaacggatgc tcgacgggcg
    16981 tcaggtcgct gtacttgccg ccctcgttgt gagtgacaca gcaggggccg ctgctctgct
    17041 cactgagacg atgcccggcg atccgtggga gcaagccgtc acggcctgtc tgaccgccct
    17101 gtcccggcgg gacgccaggc agcccgtcga cagccacctg agggatctgg cagccatctg
    17161 tcttgagcgg caggccgaac ctgggataac cgtcttcgac atccggcttg gccttaccgt
    17221 cctcgacgcg atcggctccg ccgaggcgcc cgctgcacac cgcatcgtcg aggatctcca
    17281 ccggaggaca acggacgccg aagacggcta cgcggcccgc gagaacctgg cgcatcctct
    17341 gttcgtcgcg atcgccaccg atcggcaaga acaggattgc cgcgccctgg tacgtgcctg
    17401 cgccatcggg gcagggacta tgccggacca gctgcaagca gaactgagag cggcattgag
    17461 cgccagcgac agcgtgatcc gggaaagcct tgcacgcctc tccgacccga acgcactgcc
    17521 tctgtgaagt gagcctgatg gacacacaga gcccgacaag ccgttcctcc cccgccagcg
    17581 cggcccgcgc tacctgcagg cggcgcggga agacggcatg cacgccctct ggcacgccta
    17641 cgcctccgtg ctactggacg cgggcgagag catcaaaacc ctatccgagt acctcggcca
    17701 ctcggacccg ggcttcacgc tgcggacgta cacccacctg ctgccgaagg ccgcatcagt
    17761 gccccaagcg aaaccaatgt gccctggctg cctgacggcc cctctcaggc gctaacgaga
    17821 gcgggacccg gaagccccgc ccgaacccac cggaaccccg ggctcagggc cagaccaggc
    17881 agtacgcctg atgccccgcg tcgtgcagcc ggtgggagaa gtcctgccac tcgtgcagca
    17941 gttggtagac gttgaacgcg tcacgcgggc cgccgcggtc ggggaccgtg gaccagatga
    18001 aggccgccgc gccgaccgac tcctcgccga cgtcccgcag cgggtcgacc accgtcatcg
    18061 gcagcttgac caccgcgtag tcggggtgga gcaccaccag ctccaggggc gggaccctgt
    18121 gcaggggtat gccctgtatc ccggtgagga ccatggccgc caccgtctcc ggcttgatct
    18181 tgctgaacat gccgcccatg ccgagctcgt caccgcccag ctcctccggg cgcatggaga
    18241 tgggcacgcg tgcggcggtg gcgccgtcgg gggcaccgaa gtacctgtag gtcaccccca
    18301 cccgtccacc gctcctgatc tccggagcgc gggcatcggc cggccgggcg tcccgcccgc
    18361 gtcccgcccc gcgccggtgc cgtccccgcc gggccggctc gggacccagg tcgtcggtcc
    18421 cttcgcccac tccgccaccg cgatgcatat ctcttccacc cgactacttc ttaggagaca
    18481 cagccccgcc gcgcaacccg atcatcgtgt cagtgacctc ccccacgtgc gtgcggtgaa
    18541 acacctgtcc gcaagaccgt gcgcgcctct gacaacatgg catctgtgag ctttccctat
    18601 gacgccccag ttttgcagac gcgaggagac tgacgccttt tcgttgtacg agcctcatac
    18661 ggggagagtg cgctccctgc tcaccggcgg ccggaaggac cggccagacc cccgaacccc
    18721 cgaatcgcag atcaggacca aagtggcgta ttcatacgaa gccccagttt cacagtcgct
    18781 gttcgaccgc gcgtcccgcg tgacacccgg tggcgtgaac tcacccgtgc gtgccttccg
    18841 ggccgtgggc ggtacgcccc ggttcatggt gtccggtacg ggtccgtacc tcaccgacgc
    18901 cgacggccgc gagtacgtcg acctcgtgtg ctcatggggg ccgatgatcc tcggccactc
    18961 gcacccggag gtcctcgccg ccgtccagga ggcggtcgcc cgcggtacct ccttcggtac
    19021 gcccggtgag ggagaggtcg cgctcgccga ggagatcgtg gcccgggtgg agcccgtcga
    19081 gcaggtgcgg ctcgtgtcgt ccggcaccga ggcgaccatg tccgcgatcc ggctcgcccg
    19141 cgggttcacc ggacgggcga aggtcgtgaa gttcgccggc tgctaccacg gacacgtcga
    19201 cgcgctgctg gccgccgccg gctccggcgt ggccaccttc ggcctgccgg acacgcccgg
    19261 ggtcaccggc gcccaggccg gtgacacgat cgtgctgccg tacaacgacc tggacgccgt
    19321 acgggccgcg ttcgccgcgc agcccggcga gatcgcgtgt gtgatcaccg aggcgtcccc
    19381 gggcaacatg ggcgtcgtac cgcccggcga gggcttcaac gccgggctga aggagatctg
    19441 cgcgcagcac ggcgccctgt acatctccga cgaggtgatg acgggtttcc gtacctccaa
    19501 ggccggctgg tacggcgtcg acggggtccg gcccgacctg atgaccttcg gcaaggtcat
    19561 gggcggcggc ttcccggccg cggcgttcgg cgggcgcgcc gacgtcatgg cgcacctggc
    19621 ccccgccggc cccgtctacc aggcgggcac cctctccggc aacccggttg ccaccgccgc
    19681 cggcctggcc cagctgcggc tgctcgacga cgcggcgtac gccaaggtcg acgcggtctc
    19741 cgccgagatc cggtccctgg tgagcgaggc gttcaccaag gagggcgtcg cgcacaccgt
    19801 ctcggcggcg agcaacatgt tctccgtctt cttcaccgac gggccggtcc gcgactacga
    19861 ggacgcgaag aagcaggaag ccttccgctt caccgccttc ttccactcga tgctggcgca
    19921 gggcgtctac ctgcccccgt ccgccttcga gtcctggttc gtctccacgg cccacgacgc
    19981 ccgggccgtc gagcgtgtcg ccgccgcgct gccggccgcc gcgcgggcgg cggcggaggc
    20041 cacggcatga gcggggagag cgtgagcgag gacaggggac aggacatcac cgtcgtccac
    20101 ctgatgcggc acggcgaggt gcacaacccg gagggcgtgc tctacggccg tcgctccggt
    20161 taccacctct ccgagctcgg ccggaagatg gccgaccggg tcgccgggca cctggagaag
    20221 cgcgacatca cccatgtcgt ggcctccccg ctggagcggg cccaggagac cgccgccccc
    20281 gtggccgcct cgcacggtct ggaggtggcc gtggacgagc gcctcatcga ggcggccaac
    20341 gtcttcgagg gcaagacctt cggcgtcggc gacggcgccc tgcgcaagcc ggacaactgg
    20401 aagcacctga ccaacccctt caagccctcc tggggcgagc cgtacatcga gcaggtcgta
    20461 cgcatgatgg gcgcgctgga cgcggcacgc gacgccgcgc gcggacacga ggcggtctgc
    20521 gtcagccacc agctgccgat ctggatcgtg cgcagcttcg tggagcggcg ccggctgtgg
    20581 cacgacccgc gcaagcggca gtgcacgctg gcttcgctga ccagcttcac ctaccggggc
    20641 gacaagatcg tctccgtcgg ctacaccgag ccggccaggg acctggtgcc gccgcacctg
    20701 cgggcgggcg ccaagccggt caaggggaag tccaaggcgt tcggagcctg aaccggcgtc
    20761 cacacggaca cggaggaccg ggcccgtccg cacggacggg cccggccggg tttcccaccg
    20821 gcccggggct cccgccgagc cgcgcggcgg ctgtccggcc cgcacaccct gcctggcccg
    20881 cgcaccctgc ccggcccgcc tgccccgcgc accctgtccg gtccgcgcac cctgcccggc
    20941 ccgcctgccc cgcgcacccc gctccggcct ctgcctgggc cgttcccgtg atgtggagct
    21001 cctgtaaggg tccggtcacg tagttatttt ctccgattat cggcggaacc ctcgtgttgc
    21061 ttcccccatc taagccatcg ccagtttgta tggcaatgag gtaaaaccac cgcagatggg
    21121 gacgccatgc gtgagatcaa ccgaaggggt ctgctcggag ccggactcgg agccgcggcc
    21181 gcactctcga tcgccggctg cgactcactc ggaccgtcgg gcggggacgg tccggaggcc
    21241 ggtccggaga agagcccgaa gggggaaaag ggaacccagg gcaacgggag cggccagggg
    21301 gctcccaaga agaacgtacg gatcatcggg gacggctcca catcggacac cggtaaacag
    21361 ccgaatcagc cggccgcccc cgtcccgctc gaacccgggc agaagccgcc ccagttcgtg
    21421 atcttctcct gggacggtgc cggggaggtc ggaaacggcc tcttcccccg gttcctggag
    21481 atcgcccggg aacacgacgc gaagatgacc ttcttcctct ccggtatcta tctcctgccc
    21541 gaatccagga aatccctgta ccgcccgccc aacaaccccc ggggcgcctc cgacatcggc
    21601 tacctgacgg acgggcacgt caaggagacc ctcacccacg tcggacgggc atggctcgac
    21661 ggccacgaga tcggcaccca tttcaacggg catttctgcg ccggttccgg atccgtcgcc
    21721 aactggaccc ccgcgcaatg gcagagcgag atcgaccagg cggtctcctt cgtcacccaa
    21781 tggcgcacca acagcggctg gtcggatatc gatccgctgc ccttcgacta ccgcaaggaa
    21841 ctgatcggcg gccgtacgcc ctgcctgctg ggccaggaca atctcctgcc caccgcgaaa
    21901 cagctcggct ggcggtacga cgcgagttcc cccggcggcc ggcaggtgtg gccggagaaa
    21961 cgccggggaa tctgggacct ccccctccag ggagttccct tccccggcca cagtttcgaa
    22021 gtcctctcca tggactacaa catcctcgcc aaccagtcga agaattccac caagggcgtg
    22081 cccgcccgct atcccggctg gcgcacccag gccgtcggcg cgtacctcgc cggtttcgac
    22141 cgcgcgtacg agacgaaccg cgcgcccttc tacgtcggca accacttcga ggagtggaac
    22201 ggcggcatct atatggacgc cgtcgaagaa gtgatcaaac gcatcgccgg caagccggat
    22261 gtgcgcctgg tctccttccg ccagttcgtc gactggctcg acgtacagga tccggcggta
    22321 ctcgccaagc tgcgcaccct ggaggtcgga gagtcccccg cgggtggctg gaacactttc
    22381 tttaaacagg cttgacaagg ggctttacgg gcaccgaggg gggtgcggaa gatctccgga
    22441 actgccatgc gaaacttttc acatgagctc tggccgcgta acccgacgcc gctccaccct
    22501 gctcgccgcc acggcggtgg ccggtgccct gaccctgtcc gcgtgcagtg acgacggcac
    22561 catcaccacc gggggcggcg acacgaactt cgtcaccggc aacagcggca tcgcgaccgt
    22621 ccccaagggg gagcgcaccg ccgccccgga gctggtcggc accaccctgg acgacaagcc
    22681 gctggacgtc gccgactaca agggcaaggt cgtcgtcctg aacgtctggg gctcctggtg
    22741 cgcgccgtgc cgcgcggagg cccagcactt cgccaaggtc tccaaggaga ccgcggacca
    22801 ggacgtccag ttcatcggcc tgaacaccag ggaccccgag aagtccctgg cgatcagctt
    22861 cgaggaagac cacggcgtca cctatccgag cctgtacgac ccgaggggga agctcatcct
    22921 ccgcttcccc aagggcaccc tgaacctcca gaccatcccc tcgaccgtgg tcctggaccg
    22981 cgacgggaag atcgcggccc gcaagctggg cggcctcgac gccgagaagc tgcacgagat
    23041 gatcgacccg ctgatcgcgg agaagtgacc cgtgctccag ctagccgcgc gcgggggtga
    23101 actggccgcg ctcacggggg acaacgagac cgtcctcagc ggggccctcc tgatcgccct
    23161 gcccatcgcc ctgctcgccg ggctcgtctc cttcttctcg ccgtgcgtcc tgcccctcgt
    23221 gcccggctac ctcagctacg tcaccggggt cagcggcacc gacctggccg acgcccggcg
    23281 cggacggatg gtcgccggcg cctccctctt cgtcctcggc ttcaccgcgg tcttcgtctc
    23341 cagcggcgcg ctgttcggct acttcggcca gaacgtcatg gagcacagcg acgtcctcac
    23401 caaggtcctg ggcgtgctga tgatcctcat gggggtcttc ttcatgggcc tgatgccctg
    23461 gatgacccag cgcgagttcc gcatccaccg gaaaccggtg accggactgc tcggcgcgcc
    23521 cgtgctcggc gcgctcttcg ggatcggctg gacgccctgc ctgggtccga ccctctcctc
    23581 ggtcaccgcg ctcgcgatgc agcaggggac cgcgggacgc ggtgccgtcc tgtccgtggc
    23641 gtactgcgtc ggactggggc tccccttcgt cctggccgcg gtcgccttcc gtaaggcact
    23701 cggcgcgttc ggctgggtca agcgccacta cgcatgggtc atgcggatcg gcggcggcat
    23761 gatgatcgtg accggaatcc tcctgctgac gggcgcctgg gacacgctca tccaggagat
    23821 gcgtgtctgg tccgacggct tcactgtggg gatctgagtc tcatgagcaa cctgaacacg
    23881 acggacgagc gcgagatcgg caccgcgggc gaacagctct ccaccgcccc gcgcgaggag
    23941 tccgccacca ccgtgcccgc cctgggggtc atcggctggg cccgctggtt ctggcggcag
    24001 ctcacctcga tgcgggtcgc cctgatcctg ctcttcctgc tgtcgctcgg cgccatcccc
    24061 ggctcgctga tcccgcagaa cagcgtggac gagatgaagg tggaggcgtt caagggtgac
    24121 cacaccaccc tcaccccgct ctacgagaag ctgcagttct tcgacgtcta cagctcggtg
    24181 tggttctcgg cgatctacat cctgctgttc atctccctga tcggctgcat cgtcccgcgc
    24241 accggccagt tcgtcggaca gctccgcagc cgccccccgg gcgcgccgaa gaagctgacc
    24301 cggctgcccg cctacaccac ctggcgcacc gaggcggagc ccgagcaggt ccgcgaggcg
    24361 gccctcgccg tcctgcgcaa gcggcggttc cgctcgcaca cggccgggga cgccgtcgcc
    24421 gcggagaagg gctacctccg cgaggccggc aacctgctct tccacatcgc gctgatcgtc
    24481 atgctcatcg ccttcggctg ggggcagctc ttcaagttcg agggcggcaa gctggtcctc
    24541 gaaggcgacg ggttctccaa caccaggacg cagtacgacg acttcaggcc cggcacgctc
    24601 ttcaccgacg aggacctcgt ccccttcagc ttcggcctcg acgcgttcga gggcacctac
    24661 gagcgcaccg gcccgcagcg cggcaccccc cgcaccttcg aggcccatgt cacctactcc
    24721 gagggtgtcg acgggaagcc gaagaagaag gtcgtccagg tcaacaagcc gctcgtcgtc
    24781 gacggcacca aggtctacct caacgcccac ggctacgcgc cggtcgtctc cgtcaaggac
    24841 ggcaggggca aggaggtcta ccggaacgcc gtgccgctgc tgccgcagga cgacaacatc
    24901 acctccaccg gcgcgatcaa ggtgctggac ggctaccggg acgcgaacgg cgagaagacc
    24961 cagctcggct tccaggcctt cttcgtcccg accttcgccg gcaacggcaa gggcacgatg
    25021 ttctcgcagt tccccgccct ggactacccg gtcctcgccc tcaacggctt ccacggcagc
    25081 ctcggtgtcg actccgggct gccgcagaac gtctaccagc tcgacccctc caagatggag
    25141 atgttcaagg acggcagcgg caaccagctc aagcagcggc tgcgtcccgg cgagaccatg
    25201 acactgcccg acggcgccgg ctcgatcacc ttcgagggcg tcgaggaatg ggccagtttc
    25261 cagatctccc gccagcccgc cgcgggctgg gccctcaccg gtgcggtcgc cgccatcgcc
    25321 gggctcgccg gatcgctctt catccagcgc cgccgcgtgt gggtccgggc cgtgcccggc
    25381 ccggacgggg tgaccgtggt ggagatggcc gggctcggcc gcagcgagtc cgcgaagctc
    25441 cccgaggagc tggccgatct cgcggtcgag ctccacaccc aggcgcccac cgcaccggaa
    25501 cccgagtccg ggaccgggac cgagtccgac caaccctcag aagaacctgc cgaaggggct
    25561 gagaagtgaa tctcgccgcc gcaaccaacg agaatctggc gactgtcagc aacacgctga
    25621 tctattcgtc gatggccgtc tacaccctgg ccttcttcgc gcacatcgcg gagtgggtgc
    25681 tcggcagccg cagcaaggtc ggacgtacgg ccgccgcgct gaaggagggc tcgggcaccg
    25741 ccggcggcgc ggcggtgaag gtgcgggccg cccggaagaa cggctcgacc gccgtcctcg
    25801 accggcccga ggtcgtcacc cggtccgccg ccggcacccg tgacctcccg gacggccccg
    25861 gagcggcggg cggcaccttc aagggcgacc tgtgggggcg catcgcggtc tcgctgaccg
    25921 tcctcgcctt cgccgtcgag gcgggcggtg tcatcgcgcg cgccctgtcg gtgcggcggg
    25981 ccccctgggg caacatgtac gagttctcga tcaccttctc cacggtggcc gtcggcgcgt
    26041 acctcgtcct gctggcactg aagaagaacg tccgctggat cggcctgctg ctggtgacca
    26101 cggtcctgct ggacctcggc gtcgccacca cctggctcta caccgacagc gaccagctgg
    26161 tgcccgctct gcactcctac tggctgtgga tccacgtctc caccgccatc ctctgcggcg
    26221 ccgtcttcta cctcggagcc gtcggcaccc tgctgtacct cttccgcgac tcctacgaga
    26281 acaagctggc gaacggcggt acgcccggga agttcgc
//
