LOCUS       NZ_CP023702            22712 bp    DNA     linear   CON 23-APR-2024
DEFINITION  Streptomyces nitrosporeus strain ATCC 12769 chromosome, complete
            genome.
ACCESSION   NZ_CP023702
VERSION     NZ_CP023702.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nitrosporeus
  ORGANISM  Streptomyces nitrosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7581562)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008704555.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:20:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,704
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,461
            CDSs (with protein)               :: 6,461
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 66 of 146
            Pseudo Genes (incomplete)         :: 106 of 146
            Pseudo Genes (internal stop)      :: 16 of 146
            Pseudo Genes (multiple problems)  :: 38 of 146
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 4109638
            Orig. end                         :: 4132350
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023702.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22712
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="18"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22712
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22712
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12712](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12712)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     gene            complement(1475..2257)
                     /locus_tag="CP967_RS18325"
                     /old_locus_tag="CP967_18390"
     CDS             complement(1475..2257)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155429.1"
                     /locus_tag="CP967_RS18325"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18390"
                     /product="SURF1 family protein"
                     /protein_id="WP_150489010.1"
                     /transl_table=11
                     /translation="MYRFLLTPRWWGINLFVVLAIPFCVFMGTWQLGRFEDRVQSHEEA
                     ENRPDPGTRAAKPLDELLPVSTETSGRPAVATGTYADQFLVPGRELDDRTGSYVLALLR
                     TDGGKALPVVRGWLPGTPDRAEIPAVPAGQVTVTGDLQASENTGSDGVVAGGGLPDGQL
                     GMISAAALVNLVPYDVYDAWVTLTGPGPGSGAGGALEPVPAAAAQGSGLDLKAFQNLGY
                     TGEWFVFGGFVLFMWFRLVRREAEAARDVELGLAADAD"
     gene            complement(2396..4201)
                     /locus_tag="CP967_RS18330"
                     /old_locus_tag="CP967_18395"
     CDS             complement(2396..4201)
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_S9"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007453003.1"
                     /locus_tag="CP967_RS18330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18395"
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="WP_150491920.1"
                     /sec_met_domain="Peptidase_S9 (E-value: 2.4e-39, bitscore:
                     133.6, seeds: 64, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPRWEQRFRAPRVSLPDWAEDAPDRSLFVSNATGTYELYAWDRAS
                     GKQRQVTDRPNGTTDGVLPPDGASVWWFSDTDGDEFGVWMRQPFEGGPDEPATPGLGPS
                     YPAGLAIGRDGTAVVGRSTDEDGTTVHVVRAGTDPVEIYRHRESAGVGDLSHDGSLIAL
                     EHTEHGDAMHSALRVVRPDGTTVAELDDTEGGTKELGLSVLGFAPVDGDTRLLVGHQRR
                     GRWEPMIWDPVAGTQTDLPVDLPGDVGAEWYPDGSALLIEHSFEARSELWRYEPGAAGP
                     VRVETPAGTVSGATARPDGSVEYLWSSAEQPPVVRSTTGDVVLDPPGEKAPPSVPVRDV
                     WVEGPGGRIHALVQTPSGGEGPFPTVFEIHGGPTWHDSDSFASGPAAWVDHGFAVVRVN
                     YRGSTGYGRAWTDALKHRVGLIELEDIAAVREWAVESGLADPERLVLAGGSWGGYLTLL
                     GLGTQPGSWALGLAAVPVADYVTAYHDEMEALKAMDRTLLGGTPEEVPERFEASSPLTY
                     VDAVRAPVYISAGVNDPRCPIRQVENYVDRLAARGAVHEVYRYDAGHGSLVVDERIKQV
                     RLELDFALRHLAGAPRPETAPRPGP"
     gene            complement(4788..5582)
                     /locus_tag="CP967_RS18335"
                     /old_locus_tag="CP967_18400"
     CDS             complement(4788..5582)
                     /EC_number="3.1.-.-"
                     /GO_function="GO:0016788 - hydrolase activity, acting on
                     ester bonds [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018102126.1"
                     /locus_tag="CP967_RS18335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18400"
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="WP_150489011.1"
                     /transl_table=11
                     /translation="MSVRTFWASVSTLALGAAAVLGLAQPASAAGDNYVALGDSYSSGV
                     GAGSYTSESGDCKRSTKAYPYLWRDANAPASFKFVACSGATTTTVAGSQLSALSSSTTL
                     VSITAGGNDVGFADVMQTCVLQSQATCVSRVNTAVSQVQNTLPGRLDSLYSSIRSRSPQ
                     AHVVVLGYPRFYKLSGSCIAGLTETERGAINNASDILNGVIAKRAADAGFTFSSVVDEF
                     TGHELCSGDAWLHSVTLPITNSYHPKVAGQSGGYLPAFRSAA"
     misc_feature    complement(5576..5586)
                     /note="TFBS match to HypR, L-hydroxyproline utilization
                     repressor, confidence: weak, score: 18.59"
                     /tool="antismash"
     misc_feature    complement(5698..5711)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 17.89"
                     /tool="antismash"
     gene            complement(6202..8118)
                     /gene="htpG"
                     /locus_tag="CP967_RS18340"
                     /old_locus_tag="CP967_18405"
     CDS             complement(6202..8118)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0051082 - unfolded protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0006457 - protein folding [Evidence IEA]"
                     /codon_start=1
                     /gene="htpG"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014155434.1"
                     /locus_tag="CP967_RS18340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18405"
                     /product="molecular chaperone HtpG"
                     /protein_id="WP_150489012.1"
                     /transl_table=11
                     /translation="MPAETFEFQVEARQLLQMMIHSIYSNKDVFLRELISNSSDALDKL
                     RLETLRDESLRADTSDLHIAVEADEEKRTLTVRDNGIGMSHDEVVQLIGTIARSGTAKF
                     LQELKEAKDSATSEELIGQFGVGFYSSFMVADEVTLLTRRAGEEQGTRWNSDGEGTYTV
                     ETVDDAPQGTSVTLRLKPEDTEDRLFDYTSPWKLREIVKRYSDFITWPIRMAAVTPAED
                     GTEPAAETVNSMKALWARSKDSVSDEEYSELYKHISHDWTDPLETIRMQAEGTFEYQAL
                     LFLPSHAPQDLFMQGHKRGVQLYVKRVFIMDDCEALMPSYLRFVKGVVDAQDLSLNVSR
                     EILQQDRQIELMRRRLAKKVLSTVKDMMSASPENYRTLWKEFGRVLKEGLLQDFENRDA
                     ILEISSFASTQDEEGLTTLRSYVERMKEGQEQIYFMTGESRAAMESSPHMEAFRAKGLE
                     VLLLTDPVDEVWVQSVPEFDGRQLQSIAKGEVDLDTDEEKAKAEEEREKQQEEYAGLLA
                     WMTERLGETVKEVRLSSRLTVSPACIVSDTHDVTPALENMYRAMGQEVPHIKRILELNP
                     SHALISSLRKAHAERGGEADAGTELAEAAELVHGLALLSDGGELSDPARFSRLMADRLE
                     RTL"
     misc_feature    8128..8144
                     /note="TFBS match to RicR, Copper-responsive regulator,
                     confidence: weak, score: 21.06"
                     /tool="antismash"
     gene            complement(8242..8895)
                     /locus_tag="CP967_RS18345"
                     /old_locus_tag="CP967_18410"
     CDS             complement(8242..8895)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014046892.1"
                     /locus_tag="CP967_RS18345"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18410"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_150489013.1"
                     /transl_table=11
                     /translation="MTGPATPPYGPLDPDDARAALPLAGTGAHGTLRADAARNRTRLLD
                     AASRLMAGCGAANLTMESVAAAAGVGKGTVFRRFGDRVGLLVALLDHREKLLQAAFLSG
                     PPPMGPGAPAVERLHAFGPALMRHEREHLELTLASRADPLRTYSMPASRLRVSHVAMLL
                     RQAHVEGDTELLAHTLLGSADAALVHHLTVERGLGIERLDQGWHDLVDRLGARL"
     gene            9008..9568
                     /locus_tag="CP967_RS18350"
                     /old_locus_tag="CP967_18415"
     CDS             9008..9568
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009063139.1"
                     /locus_tag="CP967_RS18350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18415"
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="WP_150489014.1"
                     /transl_table=11
                     /translation="MSVRVLALVGSLRAGSHNRQLAEAAVKHAPAGTDVELFEGLADLP
                     FYNEDLDVEGSVPAAAARLREVAGGADAFLLFSPEYNGTMPAVLKNAIDWLSRPFGAGA
                     LSGKSVAVVGTAFGQYGGVWAQDDARKAAGIAGATVLADAKLSVPGSVTRFAETHPADD
                     AEVVASLTEVLRQIAEQAAPAAA"
     gene            complement(9666..9914)
                     /locus_tag="CP967_RS18355"
                     /old_locus_tag="CP967_18420"
     CDS             complement(9666..9914)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="CP967_RS18355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /old_locus_tag="CP967_18420"
                     /product="hypothetical protein"
                     /protein_id="WP_150489015.1"
                     /transl_table=11
                     /translation="MSTQLPVSIHKTEDALPSASPETAVVRLVSLLPQDWSVSPAGTTE
                     ATATLTVTAPDGTTQAQVLRTVDEALSASPMQGWARS"
     gene            complement(10001..12712)
                     /gene="lanKC"
                     /locus_tag="CP967_RS18360"
                     /old_locus_tag="CP967_18425"
     CDS             complement(10001..12712)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007265715.1"
                     /locus_tag="CP967_RS18360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18425"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_150489016.1"
                     /sec_met_domain="micKC (E-value: 9.9e-198, bitscore: 657.6,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 5.6e-11, bitscore: 40.9,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="APH (E-value: 3.6e-07, bitscore: 29.0,
                     seeds: 156, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.9e-06, bitscore:
                     24.9, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLRHVAHCPPGTPFYDRPAAVTGEEVFPLAAAEPPAGWTRSAMG
                     EWTALTPPDPRLPTQGWKIHVSATAGSAPEVLDAVRDYCFRRSLLFKFLTTPGMLMLRN
                     SKYGDRGSSGKFITLYPRDEAELRLVLEELDELIGGRPGPAVLSDLRWRRGPLYVRYGG
                     FTLRMGRGPSGESVPCIEDPDGNLVPDVRGPAFRPPAWVPLPPFIAQALADRNKGGGLG
                     SFPFKITQALHFSNGGGVYRATDTRDGRPVLVKEGRPHAGLDDTGADAVARLRHEYEAL
                     AALDGLPAFPRVLDWRKGNEHWFLTREYVDGEPLGKEATARNPLVHAVTARQTAMSLDG
                     YTRWALDVLDRIEDAVSSMHERGLVFGDLHPNNVLIRPDGSIAFIDLETTRPAEDHTGQ
                     AIGAPGFAAPAGTTGTAVDRYALGCIRLSVFLPLTALLSWAPHRAEELIARITERFPVP
                     EDFGARVRADLALGAGVSAKSPAAVPGGRPGVSAVPAAGASGETGPRAEPVDGPLATAG
                     RIGAGVLASATPERTDRLFPGDADQFSHPDGGLNIANGAAGVLWALHGAGIEVPEPYVD
                     WLAEAARRERSARPGLYDGLAGIACVLHDLGRPDAAAELLDRALARPREHHRDGSPDHS
                     LAAGTAGLGMALLHLAGRRGDDSLAREAHRLADELADGLSARLSGDGASAAWPGPESGR
                     RPGLLRGGSGEALFLLTAHGPDHDLLDAAHAALTHDLLVSGRLPGAPTAPQPPAPWHAH
                     QLAYGGAGQAIAVHAFLARRRDPRLTAVQDVLLTDLTSEFHPACGLFTGKAGALAALVH
                     TDDGSDATRRAIGALTAGLELFAVPQEDGATGFLGDHLLRLSTDLASGSAGVLAALTAA
                     RNGTGVLPCVPLAPGAPPEPTGPEPVRAAAAG"
     gene            complement(12758..14404)
                     /gene="mpaP"
                     /locus_tag="CP967_RS18365"
                     /old_locus_tag="CP967_18430"
     CDS             complement(12758..14404)
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="mpaP"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002407.1"
                     /locus_tag="CP967_RS18365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18430"
                     /product="daptide biosynthesis intramembrane
                     metalloprotease"
                     /protein_id="WP_150489017.1"
                     /transl_table=11
                     /translation="MPATLSAAAPDLERPRTAGDVAVHEPLTEGAPWVIQRGEHQHFRT
                     SENVARLVRLLDGSRDHDQLASELGRPWTPDHVDRAVRNLAESHLLDDGTPARRVRRVR
                     FAGPLTIQFTLLKPERMLRRLTPLIRPLTHRAVLAGAAAVILFGVLALAASGPTLGAAL
                     SRPMPLWSYAAVMLGVMLTTAVHEMAHGAVLTHHGGKPSRMGFMLFYMSPAFFCDVSDG
                     WRLPAPRQRVQVALAGIAVQAVAAGAAGITALFVPAGPPRDTLLLVSLVNYMTCLVNLL
                     PLVKLDGYIALMSHLDISHLREKAMTDARRFLARVLFGGRGYDRELSGRRWAVPYGLAC
                     LLFPLYLVSTALTLWSSIFQRLGIAGSVLMLCGLGYLLWRLGKGTAVLVKDALRAGARP
                     FRIAAAGLLAAVSFGLVATLVQVPATVSAGYTTESDGSLSLLVPEGGSGFELEEGTSVT
                     LRRSGLFSRPEVGTAELGEPVGRETLAPLTAMLPVDNDRPWLAMRAYPLERGATTPAAD
                     GPDHTGVAEVKAGDHPLWKWFAVSYLGPILP"
     gene            complement(14479..15219)
                     /locus_tag="CP967_RS18370"
                     /old_locus_tag="CP967_18435"
     CDS             complement(14479..15219)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002406.1"
                     /locus_tag="CP967_RS18370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18435"
                     /product="ABC transporter permease"
                     /protein_id="WP_150489018.1"
                     /transl_table=11
                     /translation="MRNLVAGEARKALTGHIWWYLPLAGAWLCLISTFGYVSGGEKAIA
                     SGSTALAVSQDVARAWMMMFLLASVFGAVAVTRDYGSGTMTRSVLLAGSRTRLFSAKLI
                     VATAAGALFGVLAAALGTASVYLAPGAFGFEAAVDGETALILFGVFVCCTLAGPWGALV
                     GWIARNQTVAVVTLLLLTLLVDPGLQRIVPEAAQYLLTIAMSSIYRDVKPDLLSLPMAY
                     AVTAAWLIAAFFVARRLVRTRDIA"
     gene            complement(15212..16009)
                     /locus_tag="CP967_RS18375"
                     /old_locus_tag="CP967_18440"
     CDS             complement(15212..16009)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482718.1"
                     /locus_tag="CP967_RS18375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18440"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_150489019.1"
                     /transl_table=11
                     /translation="MTTNDAAVSLSHLTKTYKGVTAVEDLSVDIRAGRVTGLLGRNGAG
                     KTTTLRMLLGLATPTAGTATVLGKPYAELPHAAHRVGVSMDGMGGTPGATVRGELRIWC
                     TVLGLPATRADEVMEITGIADAATRPVKGCSTGMRQRLALAAALLADPEVLILDEPANG
                     LDPDGIRWLRDTLRSLAGEGRTVVVSSHQLAELEQTVDDVVIMQRSLRYAGTLDDLTGH
                     GAVRLEDRFFELVDPAATAPATRTPATAAPAAARTPERITSRA"
     gene            complement(16158..16301)
                     /locus_tag="CP967_RS34045"
     CDS             complement(16158..16301)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482722.1"
                     /locus_tag="CP967_RS34045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="daptide-type RiPP"
                     /protein_id="WP_167535402.1"
                     /transl_table=11
                     /translation="MNDKLDTVAIDADSLELGLQELEALEAPGFWEGVSIGIAISTVTI
                     AT"
     gene            complement(16360..16503)
                     /locus_tag="CP967_RS34050"
     CDS             complement(16360..16503)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482722.1"
                     /locus_tag="CP967_RS34050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="daptide-type RiPP"
                     /protein_id="WP_167535402.1"
                     /transl_table=11
                     /translation="MNDKLDTVAIDADSLELGLQELEALEAPGFWEGVSIGIAISTVTI
                     AT"
     gene            complement(16562..16705)
                     /locus_tag="CP967_RS34055"
     CDS             complement(16562..16705)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482722.1"
                     /locus_tag="CP967_RS34055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="daptide-type RiPP"
                     /protein_id="WP_167535402.1"
                     /transl_table=11
                     /translation="MNDKLDTVAIDADSLELGLQELEALEAPGFWEGVSIGIAISTVTI
                     AT"
     gene            complement(16764..16910)
                     /locus_tag="CP967_RS34060"
     CDS             complement(16764..16910)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005482722.1"
                     /locus_tag="CP967_RS34060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="daptide-type RiPP"
                     /protein_id="WP_167535403.1"
                     /transl_table=11
                     /translation="MNEKFENTALDLDSLELGLQELEAMEAPGWWTTGGVVVGISIVSI
                     VAT"
     gene            complement(16975..17121)
                     /locus_tag="CP967_RS34065"
     CDS             complement(16975..17121)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002403.1"
                     /locus_tag="CP967_RS34065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="daptide-type RiPP"
                     /protein_id="WP_167535404.1"
                     /transl_table=11
                     /translation="MNEKFENTALDLDSLELGLQELEAMEAPGWWTTGGVVVGVSLVSV
                     VLT"
     gene            complement(17212..18414)
                     /gene="mpaC"
                     /locus_tag="CP967_RS18380"
                     /old_locus_tag="CP967_18445"
     CDS             complement(17212..18414)
                     /codon_start=1
                     /gene="mpaC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF041822.1"
                     /locus_tag="CP967_RS18380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18445"
                     /product="daptide-type RiPP biosynthesis dehydogenase"
                     /protein_id="WP_150489020.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.2e-32, bitscore: 111.8,
                     seeds: 218, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIAWSGSTRLLVGSAGLADWLEDFEDARGDSGPAGTALLLDPAV
                     AESSVTALVTEELDRAGHTVRRIVPDGDGGPDEILALAGATADAGLIAAVGGGSLIDRA
                     KLLAVAHEDPRARAALRTTGRSGLLTLDPRTRRSRPLLAVPTTIGTGAELSRVACLPHN
                     SGKRLVMSDALAPDAALLDPSATETLPADLLVEGVLEALFRTIGPYIGNLLDRPVEDAL
                     SEAAATQLVRLGGEAARQLAAGRMPGAELRTDLARLSGLTQSTWFSYGRDLFSTEGWMI
                     ANELSSALGARKMTAVAALLPSLWQAVLAGDTRLGSAPRLRRVWDLLRSADSSGDPLPA
                     EPAAGISALMDRWGVARDLTLTPPLRETVARRTVRTWGAGLPMLGGLRAADVNALLTAA
                     A"
     gene            complement(18411..19712)
                     /gene="mpaD"
                     /locus_tag="CP967_RS18385"
                     /old_locus_tag="CP967_18450"
     CDS             complement(18411..19712)
                     /NRPS_PKS="Domain: Aminotran_3 (38-367). E-value: 6.8e-65.
                     Score: 211.2. Matches aSDomain:
                     nrpspksdomains_CP967_RS18385_Aminotran_3.1"
                     /codon_start=1
                     /gene="mpaD"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013002401.1"
                     /locus_tag="CP967_RS18385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18450"
                     /product="daptide-type RiPP biosynthesis aminotransferase"
                     /protein_id="WP_150489021.1"
                     /sec_met_domain="Aminotran_3 (E-value: 4.1e-64, bitscore:
                     215.3, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTETTLTPLPEEAGTRSHPALWTSLLPPSAHGDDSICAVSAQGMR
                     VRFADGSELLDGDSGLWNANLGHGNENIARAAYEALRDASYLSVFRYEHTYARRAAEAL
                     VALCGADHFARVLFSTSGGAANDLVMKTARHYHALRGQASRKIVVGLRGSYHGLTFGGF
                     ALTGENLGQQVYGVDQRLVRHVTPNDPGDIEKLMRAQGRQVAAVVVEPVLGSGAVPLTD
                     EYVDTLLRLRDEYGFLLAADEVATGFGRTGDMFASQRWSGRPDLLVTSKGLTNGTCAAA
                     AVVVSREVADVFRDEDATLTHGETQAGTPVTCAAILATIEEMRRLDAVALGRRAAEVLG
                     TALDRLVEGHPLFDSADGRGLFRSLRIRTAGGGLLPQAEVLGQIAAIRAAGAIVHAGVH
                     GVQIMPPLTATDAEIQELVEAVRTGVEHFAGGIR"
     aSDomain        complement(18612..19598)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP967_RS18385_Aminotran_3.1"
                     /evalue="6.80E-65"
                     /label="CP967_RS18385_Aminotran_3.1"
                     /locus_tag="CP967_RS18385"
                     /protein_end="367"
                     /protein_start="38"
                     /score="211.2"
                     /tool="antismash"
                     /translation="VSAQGMRVRFADGSELLDGDSGLWNANLGHGNENIARAAYEALRD
                     ASYLSVFRYEHTYARRAAEALVALCGADHFARVLFSTSGGAANDLVMKTARHYHALRGQ
                     ASRKIVVGLRGSYHGLTFGGFALTGENLGQQVYGVDQRLVRHVTPNDPGDIEKLMRAQG
                     RQVAAVVVEPVLGSGAVPLTDEYVDTLLRLRDEYGFLLAADEVATGFGRTGDMFASQRW
                     SGRPDLLVTSKGLTNGTCAAAAVVVSREVADVFRDEDATLTHGETQAGTPVTCAAILAT
                     IEEMRRLDAVALGRRAAEVLGTALDRLVEGHPLFDSADGRGLFRSLRI"
     gene            complement(19712..20536)
                     /gene="mpaM"
                     /locus_tag="CP967_RS18390"
                     /old_locus_tag="CP967_18455"
     CDS             complement(19712..20536)
                     /codon_start=1
                     /gene="mpaM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1248: methyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353340.1"
                     /locus_tag="CP967_RS18390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18455"
                     /product="daptide-type RiPP biosynthesis methyltransferase"
                     /protein_id="WP_229888486.1"
                     /transl_table=11
                     /translation="MGAMLLSPALAGTPLTGRAAEAVAGLGEQAVLCDLYDEAGAPVYH
                     DIAGTTPHEVRELLAALRRLPGPVLDLAAGSGRLTFPFLGLGREVTALELSEDMIGLLR
                     ERLAATPPSLRGRCTPVRADMSDFALGRRFGAVVLGTTSVSLLPPEARPGLYRCVREHL
                     APGGRFLITTVEVDPAADGTDESEILAEGQSGRTYRMIEQWSAGATTRTVTMIPAEPPA
                     EGPVTVATTTIGVLPAQRLIAELEQAGYAVRSLTPVPGGGRHHDVLLEAEAL"
     gene            complement(20536..21606)
                     /gene="mpaB"
                     /locus_tag="CP967_RS18395"
                     /old_locus_tag="CP967_18460"
     CDS             complement(20536..21606)
                     /codon_start=1
                     /gene="mpaB"
                     /inference="COORDINATES: protein motif:HMM:NF041823.1"
                     /locus_tag="CP967_RS18395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_18460"
                     /product="daptide biosynthesis RiPP recognition protein"
                     /protein_id="WP_190175148.1"
                     /transl_table=11
                     /translation="MTHSSAKAHALQWGTGRPVSALSARPPYTSTVVLEDASHLDALLG
                     SGVAGPGTTVLVPGDEPSAEPVRHEPTGAEIITWQGSLGEPGAEAGLHPDFYLQVQAYS
                     ITPYLSVLGPTLVRITEEADFQAYLDDAGRALDQGEFSEYLTHPAVQLGDLSALGGGPG
                     EDGPGLRLYVAADGTVSVSPGGAPLGPVGTPRDELHRAWQEFPDALGAVPDSASRAREL
                     ASRPWTGRYLAALGAVREAVTRGMEQPRVSGFGGRMTEALNGFAEPFDRSATAPLLLHN
                     GERALIHHPVDRRTVALSTDAALAAEALLVTGSAQEAARYAAPDTVDAVAAYFAGIGLP
                     LTESAEPRTVTEEVNA"
     misc_feature    22135..22149
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 25.84"
                     /tool="antismash"
ORIGIN
        1 gccccgccga cgcccctggt ttccccggcc ccttgggcgc gtccggcccc gccgtgtgcg
       61 gtggtacgga agccggtggt ccggaaacgg aaggcccgga aacagaagac gcggaaacgg
      121 aaggcgcggg cggtgagggc ggcggtgcag aaccggccgg agccggcggc accctgacgg
      181 cgctcttcgg tgccggcgca ggctccggcc gtcgtgctga cggccctttc gcttccggcg
      241 gcatcgtgga cgagacggcg ctgcgccgga tgatgcaggg ggcggtcggc ggcctcgaac
      301 ccgccgaggg ggtcctcgac cacttgcagc gcgccgttcc cgcccgacgg gccagacggc
      361 gtcaggccgt cgtgggcgcc gccgctgccg ccctgctcat cggtacggcg gtccccgcct
      421 tcctccatgt ggcgaactcg gaggggtcgg tcgccgccaa cccgtccatc gccggccacg
      481 gggaacaggc ccagggcggc aacggccagg acacgggcgc ccggacgagc ggccaggact
      541 ccggcggtgg tcccgccgcc cggcagagcg agggcagcag ccaggggcag accgacccgt
      601 ccgccggccc gacgcaggag cccggggcgg gctccgacgg ctccggtgcc gagggtgccg
      661 acgccacacc gggcaccgat gcggcggagg tgccggcctg cgacccgggc cagctggggg
      721 tggcgtccgc cgaggcgggc gccccgggtg cggacggcaa ggtgtacggg agtttcagga
      781 tctccaacgt ctcgggcaag gcgtgctcgg tgacgagtga cggcaccgtc ggcttccagg
      841 cggcgggggc tgccgacccc ttgaagatca ctgtcgtcca gcactccgcc ggtgatccgg
      901 ccagtggact gcccgatccc tcactggagc cgagggcggt cctgctgaag ccggcgatgg
      961 cgtacgaggt ccggttcgcc tgggtgccga cggacagctg cccgacgacc ggtggttcac
     1021 ccagccccac tcccacagtc ggtgacggcg gcgggggcac cggcggtacc ggcggtgcgg
     1081 cgggcacccc cgagggagcc tcggacacgg cggcgcagtt cggcgccgcg gacgagaccc
     1141 cggccaacgg cagtatcgcg gtgacgcaca caccggagac cggtgcgccg accgccgaga
     1201 ccacgatccc ccacgcctgc gcgggcacca tctaccgcac gggagtgctg gacgcctcgt
     1261 aacccacggg cggacggccg aggacgtgac ggaaccggtc cgggccggtc cgccggcgga
     1321 ccggcccgct tccacccggg caagggatgc ggcccaggcc ggcctccgca cgggcggggc
     1381 cgcgtccggg ccggtaccac tcggacgagg gatgcgcccg agccggttcc gcccggcccg
     1441 gggaacgtcc gggtctgtcc ggcccggccg gatgtcagtc ggcgtcggcg gcgaggccca
     1501 gttcgacgtc acgcgccgcc tcggcctcgc ggcgcaccag gcggaaccac atgaagagca
     1561 cgaaaccgcc gaagacgaac cactcgccgg tgtagccgag gttctggaag gccttcaggt
     1621 ccagcccgct gccctgagcc gccgcggcgg gcaccggctc caacgcaccg ccggccccgg
     1681 accccggccc ggggccggtg agggtcaccc aggcgtcgta cacgtcgtac gggacgaggt
     1741 tgaccagggc ggccgcgctg atcatgccca gctgcccgtc gggcaggccg ccgccggcga
     1801 ccaccccgtc gctgccggtg ttctccgaag cctgcaggtc gccggtcacc gtgacctgcc
     1861 cggccgggac cgccgggatc tcggcgcggt ccggtgtgcc gggcagccag ccgcgcacca
     1921 caggcagcgc cttgcccccg tcggtgcgca gcagggccag cacgtaggag ccggtccggt
     1981 cgtccagctc gcgcccgggg acgaggaact ggtccgcgta cgtccccgtc gccacggcgg
     2041 gccggcccga ggtctcggtg ctgaccggaa gcagctcgtc gaggggcttc gccgcacggg
     2101 tcccgggatc gggccggttc tcggcctctt cgtgcgactg cacgcggtcc tcgaaacggc
     2161 cgagctgcca tgtccccatg aacacgcaga acggaatcgc cagcacgacg aagaggttga
     2221 tcccccacca ccgcggggtc agcaggaacc ggtacacccc accacggtac ggtctcccgc
     2281 tccggtcccc cggagcgggg tgcaccattt atccgggcct tacgccgtcc cgggcgccct
     2341 tcagctgtgt gtacgggtac tccggttcaa tctgtacgga tcccgtggct ccccctcacg
     2401 gccccggccg gggagcggtc tccggccgcg gtgcccccgc gaggtgccgc agcgcgaagt
     2461 ccagctccag ccgcacctgc ttgatccgtt cgtccacgac gagcgagccg tgtcccgcgt
     2521 cgtagcggta cacctcgtgc acggcgcccc gggcggccag ccggtccacg tagttctcca
     2581 cctggcggat ggggcacctg gggtcgttga ccccggccga gatgtagacc ggggcgcgca
     2641 cggcgtcgac gtacgtcagc ggggacgatg cctcgaaccg ctccggcacc tcctcgggtg
     2701 tgccgcccag cagcgtgcgg tccatcgcct tgagggcctc catctcgtcg tggtacgcgg
     2761 tgacgtagtc ggcgacgggg accgccgcca gcccgagcgc ccaggagccg ggctgggtgc
     2821 cgagcccgag cagggtcaga taaccgcccc acgatccgcc ggccaggacc agccgctccg
     2881 ggtccgcgag acccgactcc accgcccact cccgcaccgc cgcgatgtcc tccagctcga
     2941 tcagcccgac ccggtgcttc agggcatcgg tccaggcgcg gccgtatccc gtggacccgc
     3001 ggtagttgac ccggacgacg gcgaacccgt ggtccaccca cgcggccggc ccggacgcga
     3061 aggagtcact gtcgtgccag gtgggtccgc cgtgtatctc gaagaccgtg gggaacggtc
     3121 cctcaccgcc ggaaggcgtc tgcaccaggg cgtggatccg cccgcccgga ccctccaccc
     3181 agacgtcgcg caccggcacg gaggggggag ccttctcccc cggggggtcc aggaccacgt
     3241 ccccggtcgt cgaccggacc accgggggct gttcggccga ggaccacagg tactccaccg
     3301 agccgtcggg cctggccgtg gcccccgaaa ccgtgccggc gggcgtctcg acacgcacgg
     3361 gccccgcggc acccggctcg taccgccaca gctcgctgcg tgcctcgaag ctgtgctcga
     3421 tgaggagcgc cgaaccgtcc ggataccact cggctcccac atcaccgggc aggtccacgg
     3481 gcaggtccgt ctgcgttccg gccaccgggt cccagatcat cggctcccag cgtccgcgcc
     3541 gctggtgtcc gacgagcagc ctggtgtcgc cgtccaccgg tgcgaacccg aggaccgaca
     3601 gccccagttc cttcgtgccg ccctcggtgt cgtccagctc cgcgaccgtc gtgccgtcag
     3661 gacgcaccac gcgcagggcg gaatgcatcg cgtcgccgtg ctcggtgtgc tccagcgcga
     3721 tcagggagcc gtcatgggag aggtcgccga caccggccga ttcccggtgc cggtagatct
     3781 ccacggggtc ggtccccgcc cgcaccacgt ggaccgtggt gccgtcctcg tccgtggaac
     3841 ggccgaccac cgcggtcccg tcccggccga tcgcgagccc ggccggatag gaaggaccga
     3901 gaccgggggt cgcgggctcg tccggaccgc cttcgaaggg ctgcctcatc cacacaccga
     3961 actcgtcgcc gtcggtgtcg gagaaccacc agacggacgc gccgtccggt ggcaggaccc
     4021 cgtcggtggt cccgttcggc cggtccgtca cctggcgctg cttccccgac gcccggtccc
     4081 aggcgtacag ctcgtacgtc ccggtggcgt tggagacgaa gagggagcgg tcgggcgcgt
     4141 cctcggccca gtcgggcagc gagaccctgg gcgcgcggaa acgctgctcc caccggggca
     4201 tccggtcccg gtccggcttc cgctcccccc gctccggtgc ccggcccgcg gcccgctcgg
     4261 cgtcggtccc ggccggcttt ccggaccggt gctgttcctg tcccccgggg gacgtctcgt
     4321 gctgtgcgtc gctcatggct ccatacaacc cgatcggacc gggtcaccgg agggcctgtg
     4381 gacaacccct ccgtcggccg cgatctgtgg acaactcgct cacccgcctg cgcggccacc
     4441 ggtcgcggcc tgtggacaac tcgtccaccg gtacacacgg cacatacggt catccggtgc
     4501 cggtgccggt gccggtaccg cgtgggacag cccggccgcg ggtcccggcg gccgagggac
     4561 agcgtgctcc ggccagtaca cccgggcggc acggacagca cgggcacagc cccgcctccg
     4621 gccggaacgc gtgcaggcgc cacccgggcc gcccgggtgg cgcctgcacg gggaggcgag
     4681 ggggagggag gatccccgtc gccgtgcaca gcccggtacc gcgcagcagg cggcgcctgc
     4741 gggaagaggc gtcaggaccc gctccgcgga ccggggccgg gcggtcctca ggccgcggag
     4801 cggaaggcgg gcaggtatcc gcccgactgc ccggcgacct tggggtggta cgagttggtg
     4861 atcgggaggg tcacgctgtg gagccaggcg tcgcccgagc acagctcgtg cccggtgaac
     4921 tcgtcgacca cgctggagaa ggtgaagccc gcgtcggccg cccgcttggc gatcacgccg
     4981 ttcaggatgt cggaggcgtt gttgatcgcc ccgcgctcgg tctcggtcag cccggcgatg
     5041 caggagcccg agagcttgta gaagcgcggg taccccagca ccaccacatg ggcctgcggg
     5101 gagcgcgaac ggatgctgct gtagagcgag tccagcctgc ccgggagggt gttctgcacc
     5161 tgtgagaccg cggtgttcac ccggctgacg caggtggcct ggctctgtag cacacaggtc
     5221 tgcatgacat cggcgaagcc gacgtcgttg ccgcccgccg tgatgctgac gagggtggtc
     5281 gacgagctca gcgcactgag ctgactgcct gccaccgtgg tggtcgtggc tcccgagcag
     5341 gcgacgaact tgaaggaggc cggggcgttc gcgtcccgcc agaggtacgg gtacgccttg
     5401 gtgctgcgct tgcagtcacc gctctcggag gtgtagctcc cggccccgac ccctgaggag
     5461 taggagtcgc cgagagcgac gtagttgtcg ccggcggcgg aagccggctg cgccaggccg
     5521 agcacagcgg cggcgccgag cgcgagggtc gagacggagg cccagaaggt acgtactgac
     5581 atggcagtca gcccttcgaa gtgtggggga tgagtgggga gttggtgcga cgagcacgtt
     5641 tgtagcagct cccggtaccc cccggtagcg tccggttgag aagtcgcctg atatgcccga
     5701 atgatcgttc ggtggggtga gctccgcgcg tagataaacc tccaggaggc cctcgggtcg
     5761 gtgaagttga gggaccttca cggtggcccg ccgacggcac ggcgccacct ccgcgccatc
     5821 tcccggacca tgcccgggtg gccggatcgt cgggtggccg ggcgggctgg gtggccgggc
     5881 ggtcgtgggg gctgggtggc cggacggtca ggcgggctgg gtggccgggt gggtcgtgcg
     5941 gctgtcgccg ctccgcacaa ctccatgtat ccccggcagt cccgaggggc ccgggccctt
     6001 cagggggcgc accgttgtga cggaggggcg tgcagaggtg cggcaggcgt gtggaagcgc
     6061 ggtggaggtg cagaggtgcg gcaggcgtgt ggaagcgcgg cggtcatgcg gaggtccggc
     6121 gggcgcgcgt acgactgcgg ccgccgggtc gtccggcggc cgcagtagca gaaaggtgag
     6181 cgcgtgcgag gatgcgccgg tctacagcgt gcgctccagg cggtcggcca tcagcctgct
     6241 gaagcgggcg ggatcgctca gctccccgcc gtccgagagc agtgcgagcc cgtggacgag
     6301 ctccgccgcc tcggccagct ccgtaccggc gtccgcttcc ccgccccgct cggcgtgcgc
     6361 cttcctcagg gagctgatca gcgcgtgcga cgggttgagt tccaggatgc gcttgatgtg
     6421 cggcacctcc tggcccatgg cgcggtacat gttctccagc gccggggtga cgtcgtgcgt
     6481 gtcggagacg atgcaggccg gggacacggt gagccgtgag gagaggcgta cctccttcac
     6541 cgtctcgccc agccgctccg tcatccaggc gagcagtccg gcgtactcct cctgctgctt
     6601 ctcgcgctcc tcctcggcct tcgccttctc ctcgtcggtg tccagatcga cctcgccctt
     6661 ggcgatcgac tgaagctgcc tgccgtcgaa ctccggcacc gactgcaccc agacctcgtc
     6721 caccgggtcg gtcagcagga ggacctccag ccccttcgcc cggaaggcct ccatgtgggg
     6781 cgaactctcc atggcggcac gggactcgcc cgtcatgaag tagatctgct cctggccctc
     6841 cttcatgcgt tcgacgtagg agcgcagggt ggtcaggccc tcctcgtcct gggtggaggc
     6901 gaacgaggag atctccagga tcgcgtcacg gttctcgaag tcctggagca ggccttcctt
     6961 gaggacccgg ccgaactcct tccagagcgt ccggtagttc tccggcgagg cggacatcat
     7021 gtccttcacc gtggagagga ccttcttggc gaggcgccgc cgcatcagct cgatctggcg
     7081 gtcctgctgg aggatctcgc gcgatacgtt gagcgaaagg tcctgggcgt cgaccacgcc
     7141 cttgacgaaa cgcaggtacg acggcatgag cgcttcgcag tcgtccatga tgaacacgcg
     7201 cttgacgtag agctgcacac cgcgcttgtg gccctgcatg aagaggtcct gcggggcgtg
     7261 cgacgggagg aagagcagcg cctggtactc gaaagtgccc tccgcctgca tgcggatggt
     7321 ttcgagcggg tcggtccagt cgtggctgat gtgcttgtag agctcgctgt actcctcgtc
     7381 gctcaccgag tccttcgacc gggcccacag cgccttcatc gagttgacgg tctcggccgc
     7441 cggctcggtt ccgtcctcgg cgggcgtcac ggcggccatg cggatgggcc aggtgatgaa
     7501 gtcggagtac cgcttgacga tctccctgag cttccagggg gaggtgtagt cgaagagccg
     7561 gtcctcggtg tcctccggct tgagccgcag ggtgaccgag gtgccctgcg gcgcgtcgtc
     7621 gacggtctcg acggtgtagg tgccctcgcc gtccgaattc cagcgggtgc cctgctcctc
     7681 gcccgcgcgg cgggtcagca gggtgacctc gtcggccacc atgaagctcg agtagaagcc
     7741 gaccccgaac tgcccgatga gctcttcgga cgtggcggag tccttggcct ccttcagttc
     7801 ctggaggaac ttcgccgtac cggaacgggc gatcgtcccg atcagctgca cgacctcgtc
     7861 gtgcgacatc ccgattccgt tgtcgcgcac ggtgagggtg cgcttctcct cgtcggcctc
     7921 gacggcgatg tggagatcgg aggtgtcggc ccggagcgat tcgtcgcgaa gggtctccag
     7981 acgcagtttg tccagcgcgt cggaggagtt ggagatgagc tcgcgcagga atacatcctt
     8041 gttcgagtag atcgagtgga tcatcatctg caggagctga cgagcttcca cctggaactc
     8101 gaatgtctcg gccggcatgg gtgcgggatc cctttctggg gtacgtcgga tggccgggac
     8161 atatcgtaac cagcggctct cccgcccggg gcggcttacc gggatcccgc ccggctcccc
     8221 ggcgggccgt gggaggaccg gctacagcct ggccccgagg cggtcgacga ggtcgtgcca
     8281 gccctggtcc aaccgctcga ttcccaggcc gcgttccacc gtcagatggt ggacgagggc
     8341 ggcgtcggcc gagccgagca gggtgtgcgc cagcagctcc gtgtcgccct ccacgtgcgc
     8401 ctggcgcagc agcatggcga catggctgac ccgcagacgg ctcgcgggca tgctgtacgt
     8461 gcgcagcggg tccgcgcggg aggccagggt cagctccagg tgctcgcgct catggcgcat
     8521 cagggcgggc ccgaaggcgt gcaggcgttc caccgcgggg gcgccggggc ccatcggggg
     8581 cggcccggag aggaaggccg cctggagcag cttctcccgg tggtccagca gcgcgacgag
     8641 aaggccgacg cggtcgccga agcgccggaa gaccgtcccc ttgcccactc cggccgcggc
     8701 ggcgaccgat tccatggtca ggttcgcggc gccgcagccg gccatgaggc gcgaggcggc
     8761 gtccagcagg cgggtgcggt tgcgtgccgc gtccgcccgg agcgtcccgt gggcgccggt
     8821 gcccgcgaga gggagggcgg cccgcgcgtc gtcggggtcg agcggcccgt acggaggggt
     8881 ggcgggaccg gtcatggctc cagggtagcc cctgagcagc ggaagtggac cacggtccgc
     8941 ttaggtggta gaactttaaa cggactacgg tccgcttgtc tcgccgcctt cctctccagg
     9001 agttcccatg tctgtacgcg tcctcgccct cgtcggcagc ctccgcgccg gctcccacaa
     9061 ccgccagctc gccgaggccg ccgtcaagca cgcgcccgcg ggcaccgacg tcgagctctt
     9121 cgagggcctg gccgacctcc ccttctacaa cgaggacctc gacgtcgagg gcagcgttcc
     9181 ggccgccgcg gcccgcctgc gcgaggtcgc gggcggggcc gacgccttcc tgctgttctc
     9241 gcccgagtac aacggcacga tgccggccgt cctcaagaac gcgatcgact ggctctcccg
     9301 cccgttcggc gccggtgccc tcagcggcaa gtccgtcgcc gtcgtcggta ccgccttcgg
     9361 tcagtacggt ggcgtctggg cccaggacga cgcccgcaag gccgccggca tcgccggcgc
     9421 cacggtgctc gccgacgcca agctgtccgt ccccggctcc gtgacccgct tcgccgagac
     9481 ccaccccgcc gatgacgccg aggtcgtcgc ctccctgacc gaggtgctcc gccagatcgc
     9541 cgagcaggcg gctcccgcag cggcctgacg cccctggcac gaccgtggcg gcgacgcgcc
     9601 gaggatgccg cgtcgccgcc acggtgcgtc cggaccgccc gtacggccgc ccgggatccc
     9661 ggggttcagg aacgtgccca gccctgcatg ggggaggcgg agagcgcctc gtccaccgta
     9721 cgcaggacct gggcctgtgt cgtgccgtcc ggggccgtga cggtcagggt ggcggtggct
     9781 tccgtcgtgc cggccggact caccgaccag tcctgaggca gcagggagac gaggcggacg
     9841 accgcggtct ccggtgacgc cgagggcagg gcgtcctccg tcttgtggat gctgaccggc
     9901 aactgcgtgg acatgaggac tccgtggtgg gggcgtgccg gcatgcggcc gagggcacgg
     9961 tgatcggtga ggggcggggg cggcggagat accggaccgg tcatcccgcg gccgcggccc
    10021 ggacaggttc cggcccggtg ggctcgggcg gggcgcccgg cgccaacggt acacagggca
    10081 ggacgccggt cccgttacgg gccgcggtca gagcggccag gacccccgcg gagccgctgg
    10141 cgaggtcggt ggacagccgc agcagatggt cgccgaggaa gccggtggcc ccgtcctcct
    10201 gaggcaccgc gaacagttcc aggccggcgg tcagggcgcc gatcgcccgc cgggtcgcgt
    10261 ccgagccgtc gtcggtgtgc accagagccg cgagcgcgcc cgccttaccg gtgaacagcc
    10321 cgcaggccgg atggaactcc gaggtcagat cggtcagcag gacgtcctgt acggcggtga
    10381 gccgcggatc ccgccggcgg gccaggaagg cgtggaccgc gatggcctgg cccgcaccgc
    10441 cgtacgccag ctggtgcgcg tgccagggcg ccggcggctg cggtgccgtg ggcgcgccgg
    10501 gcagccggcc ggagaccagc aggtcgtggg tgagggccgc atgggcggcg tcgagcaggt
    10561 cgtggtccgg gccgtgggcg gtgagaagga agagcgcctc gcccgaaccg ccgcgcagca
    10621 ggccggggcg gcggccggac tccgggccgg gccacgccgc tgacgcgccg tcaccggaga
    10681 gccgggcgga cagcccgtcg gcgagttcgt cggcgagccg gtgcgcctca cgggccaggg
    10741 agtcgtcccc gcggcggccc gcgaggtgca gcagggccat accgagcccc gccgtaccgg
    10801 ccgcgaggct gtggtccggg ctgccgtccc ggtggtgttc gcggggccgg gccagggcgc
    10861 ggtccaggag ctcggcggcc gcgtcggggc ggcccaggtc gtgcaggacg caggcgattc
    10921 cggccagtcc gtcgtagagc ccggggcggg cggacctctc ccggcgggcg gcttcggcca
    10981 gccagtcgac gtacggctcg ggcacctcga tccccgctcc gtgcagcgcc cacagcacac
    11041 ccgccgcgcc gttggcgatg ttcaggccgc cgtccgggtg gctgaactgg tcggcgtcac
    11101 cggggaagag gcggtccgtc cgctcggggg tggcggaggc gagcacaccc gcgccgatcc
    11161 gtccggcggt ggccagcggt ccgtccacgg gttccgcgcg cggcccggtc tccccggacg
    11221 cgccggccgc cgggaccgcg gacactccgg gcctcccgcc cggtacggcc gctggggact
    11281 tcgcggacac gccggccccg agggccaggt ccgcacggac ccgcgccccg aagtcctccg
    11341 gaaccgggaa gcgttcggtg atccgggcga tcagctcctc ggccctgtgc ggtgcccatg
    11401 acagcagtgc cgtcaggggg aggaagacgc tgaggcgtat gcagcccagc gcgtagcggt
    11461 cgacggccgt cccggtggtg cccgcgggag cggcgaagcc gggggcgccg atggcctgcc
    11521 cggtgtggtc ctcggcgggc cgggtggtct ccaggtcgat gaaggcgatg ctgccgtcgg
    11581 gacgtatcag gacgttgttg gggtgcaggt cgccgaagac cagaccgcgt tcgtgcatgg
    11641 aggagacggc gtcctcgatc cggtccagga cgtccagcgc ccagcgcgtg tacccgtcga
    11701 gactcatcgc ggtctgccgc gcggtcacgg cgtggaccag cgggttgcgg gcggtcgcct
    11761 ccttgccgag cggctcgccg tccacgtact cccgggtcag gaaccagtgt tcgttgccct
    11821 tgcgccagtc caggacgcgg gggaaggcgg ggagcccgtc gagcgcggcc agcgcctcgt
    11881 actcatggcg gagccgggcg accgcgtcgg cgccggtgtc gtccaggccc gcgtgcggcc
    11941 ggccctcctt gacgagcacc ggacggccgt cgcgggtgtc ggtggcccgg tagacgccgc
    12001 cgccgttgga gaagtgcagc gcctgggtga tcttgaaggg gaaggagccg agcccgccac
    12061 ccttgttgcg gtcggccagc gcctgcgcga tgaacggcgg cagcggcacc cacgccgggg
    12121 gccggaaggc ggggccgcgc acgtcgggga cgaggttgcc gtccgggtcc tcgatgcagg
    12181 ggaccgattc gcccgagggg ccgcggccca tgcggagggt gaagccgccg tagcggacgt
    12241 acagcggacc gcggcgccag cgcaggtcgc tgaggacggc ggggcccggc cggccgccga
    12301 tgagctcgtc cagttcctcc aggacgagcc ggagctccgc ctcgtcgcgg gggtagaggg
    12361 tgatgaactt gccgctgctc ccccggtccc cgtacttgct gttgcgcagc atcagcatcc
    12421 cgggggtggt gaggaacttg aacagcagcg accgccggaa gcagtagtcg cggacggcgt
    12481 cgagcacctc gggggcgctc ccggcggtcg ccgagacgtg gatcttccag ccctgcgtgg
    12541 ggagccgggg gtccggaggc gtcagcgcgg tccactcgcc catcgccgag cgcgtccagc
    12601 cggcgggcgg ttcggccgcc gcgaggggga agacctcctc accggtgacg gcggcgggac
    12661 ggtcgtagaa gggggtgccc ggcgggcagt gggcaacatg gcgcagggac atggcgggtc
    12721 ctccggagcg gcgtaccaga agtcggtggg gtggggatca gggcaggatc gggccgaggt
    12781 aggagacggc gaaccacttc cacagcgggt ggtcgcctgc cttcacctcg gcgacgccgg
    12841 tgtggtcggg gccgtccgcg gcgggcgtcg tggccccgcg ctccagcggg tacgcccgca
    12901 tcgcgagcca cggccggtcg ttgtcgaccg ggagcatcgc ggtcagcggc gccagcgtct
    12961 cgcgcccgac gggctccccg agctcggccg tgccgacctc ggggcggctg aacagacccg
    13021 agcggcgcag ggtcaccgag gtcccctcct ccagctcgaa gccggaaccg ccctcgggga
    13081 ccagcaggct gaggctgccg tcgctctcgg tggtgtaacc ggccgagacg gtggcgggga
    13141 cctggacgag ggtggcgacg aggccgaagg acaccgcggc gagcagcccg gcggcggcga
    13201 tgcggaacgg acgggcgccc gcccggagcg cgtccttgac caggacggcg gtgcccttgc
    13261 cgagccgcca cagcagataa ccgaggccgc acagcatcag caccgaaccg gcgatgccca
    13321 gccgctggaa gatcgaggac cacagggtca gggcggtcga gacgaggtag agcgggaaga
    13381 gcaggcaggc cagtccgtac gggacggccc agcggcggcc ggacagttca cggtcgtaac
    13441 cacggccgcc gaacagcacc cgggcgagga acctgcgggc atcggtcatg gccttctccc
    13501 gcaggtggga gatgtcgagg tggctcatca gcgcgatgta gccatccagc ttcaccagcg
    13561 gcagcaggtt gaccaggcag gtcatgtaat tgacgaggga gacgagcagc agggtgtcgc
    13621 gcggcggccc ggcgggcacg aacagcgcgg tgatgccggc ggccccggcg gccacggcct
    13681 ggacggcgat accggcgagg gcgacctgga cgcgctggcg gggggcgggc agccgccagc
    13741 cgtcggacac gtcgcagaag aacgccggcg acatgtagaa gagcatgaag cccatccggc
    13801 tcggcttgcc cccgtggtgg gtgaggaccg cgccgtgcgc catctcgtgg acggcggtgg
    13861 tgagcatgac gccgagcatc accgcggcgt acgaccacag cggcatcggc cggctgaggg
    13921 ccgcgccgag ggtggggccg gaagcggcga gggccaggac gccgaagagg atgacggccg
    13981 ccgcaccggc gaggaccgcg cggtgggtca gcggccggat cagcggggtg aggcggcgga
    14041 gcatccgctc cggcttgagc agggtgaact ggatggtcag cggcccggcg aagcggacgc
    14101 gccgtacgcg ccgggcggga gtgccgtcgt ccagcaggtg ggactcggcg aggttgcgga
    14161 ccgcccggtc gacgtggtcc ggcgtccacg gccggccgag ctcgctggcg agctggtcgt
    14221 ggtcacggct gccgtcgagg aggcggacca gccgggccac gttctcgctg gtgcggaagt
    14281 gctggtgctc gccgcgctgg atcacccacg gggcgccctc ggtgagcggc tcgtgcacgg
    14341 cgacgtcacc ggcggtacgg ggccgctcca ggtcgggcgc ggcggcggac agggttgcgg
    14401 gcatggtggg agcacctcgg atcggcgggc ggcgcgtgcg tggcgccggc agggcggtgt
    14461 ccgcgcggcg gcgggcggtc aggcgatgtc gcgggtacgg accaggcggc gggcgacgaa
    14521 gaaggcggcg atcagccagg cggcggtcac ggcgtacgcc atgggcagcg acagcagatc
    14581 gggcttcaca tcgcggtaga tcgagctcat cgcgatggtg agcaggtact gggccgcctc
    14641 gggcacgatg cgctgcagcc ccgggtcgac gaggagggtg aggaggagca gggtgaccac
    14701 ggcgacggtc tggttgcgcg cgatccagcc gacgagcgcg ccccaggggc cggccagtgt
    14761 gcagcagacg aagaccccga agaggatcag ggcggtctca ccgtccacgg cggcctcgaa
    14821 gccgaacgcc cccggggcga ggtagacact ggcggtgccg agcgccgcgg ccagcacgcc
    14881 gaacagggcg ccggcggcgg tcgcgacgat cagcttggcg ctgaagaggc gggtccgcga
    14941 gccggccagg agcacggagc gggtcatggt cccggagccg tagtcgcggg tgacggcgac
    15001 ggccccgaag acggaggcca gcaggaacat catcatccag gcacgggcga cgtcctggct
    15061 gacggcgagg gcggtggagc cggacgcgat ggccttctcg cctccggaga cgtatccgaa
    15121 ggtgctgatc aggcagagcc acgcgccggc gagcggcagg taccaccaga tgtgtccggt
    15181 cagggccttg cgggcttcgc cggcgacgag gttacgcacg ggacgtgatc ctttccggag
    15241 tgcgggccgc ggccggggcc gcggtggcgg gggtacgggt cgcgggggcc gtcgcggcgg
    15301 ggtcgacgag ctcgaagaag cggtcctcca gacggacggc gccgtgaccg gtgaggtcgt
    15361 cgagggtgcc cgcgtaccgc agcgaacgct gcatgatcac cacgtcgtcg acggtctgct
    15421 ccagctcggc gagctgatgg ctggagacca cgaccgtgcg gccctctccg gccagcgaac
    15481 gcagggtgtc gcgcagccag cggataccgt ccgggtccag gccgttggcc ggctcgtcga
    15541 ggatgagcac ctcggggtcg gcgagcagcg cggcggccag ggccagccgc tggcgcatac
    15601 cggtcgagca gcccttgacc gggcgggtgg cggcgtcggc gatgccggtg atctccatga
    15661 cctcgtcggc gcgggtggcg gggagtccga gcaccgtgca ccagatgcgg agctcgcctc
    15721 ggacggtggc gccgggggtg ccgcccatgc cgtccatgct gacgcccacc cggtgggccg
    15781 cgtgggggag ttcggcgtac ggcttgccga ggacggtggc ggtgccggcg gtcggggtgg
    15841 ccagtcccag gagcatcctc agggtggtgg tcttgccggc tccgttacgg cccagcagac
    15901 cggtgacgcg accggcgcgg atgtcgacgc tcaggtcttc gaccgcggtg acgcccttgt
    15961 aggtcttggt gaggtggctc agcgagacgg cggcgtcatt cgtggtcatc gccggcactc
    16021 ctgtcgtgtc gtgtcatgag gtgctccgga agtcctgatg gtgaagaggg ggagggccga
    16081 gggccgggcc caggccggga gttctcccgg cccggcccgg tcctctcgat ccgtctcggc
    16141 ttgcgccggg cggtggatca ggtggcgatg gtgaccgtgg agatcgcgat gccgatggag
    16201 acgccctccc agaagcccgg ggcctcgagg gcctccagct cctgcaggcc gagttccagg
    16261 ctgtccgcgt cgatggcgac ggtgtcgagc ttgtcgttca tggcgatgtc ctttccgtgg
    16321 gtgtgagttg tggttggtgt tgcgggtgtt gcgggtggat caggtggcga tggtgaccgt
    16381 ggagatcgcg atgccgatgg agacgccctc ccagaaaccg ggggcctcga gggcctccag
    16441 ctcctgcagg ccgagttcca ggctgtccgc gtcgatggcg acggtgtcga gcttgtcgtt
    16501 catggcgatg tcctttccgt gggtgtgagt tgtggttggt gttgcgggtg ttgcgggtgg
    16561 atcaggtggc gatggtgacc gtggagatcg cgatgccgat ggagacgccc tcccagaaac
    16621 cgggggcctc gagggcctcc agctcctgca ggccgagttc caggctgtcc gcgtcgatgg
    16681 cgacggtgtc gagcttgtcg ttcatggcga tgtcctttcc gtgggtgtga gttgtggttg
    16741 gtgctgcggg tgctgcgggt ggatcaggtg gcgacgatgg agacgatgga gatgccgacg
    16801 acgacaccgc cggtggtcca ccagccgggg gcctccatgg cctccagctc ctgcaggccg
    16861 agctccaggc tgtccaggtc gagggcggtg ttctcgaact tctcgttcat gactgcttcc
    16921 ttccgtgagt gatgcgtggt gggtggggac ggtggtccgg tcggtccggg aggatcaggt
    16981 gaggaccacg gagacgaggg acacgccgac gacgacaccg ccggtggtcc accagccggg
    17041 ggcctccatg gcctccagct cctgcaggcc gagctccagg ctgtccaggt cgagggcggt
    17101 gttctcgaac ttctcgttca tgacgtttct ccttcgtagg gctcggccgg atgccgagcg
    17161 gtggtgcgtt ccccgcgccg ggccggcgcg gaagtctgtg ggtgcggccg ctcaggcggc
    17221 cgcggtgagg agggcgttca cgtccgccgc ccgcagtccg ccgagcatcg ggagcccggc
    17281 gccccaggtg cggaccgtcc ggcgggcgac cgtttcgcgc agcggcggcg tgagggtgag
    17341 gtcccgtgcc acgccccagc ggtccatcag ggcgctgatg cccgctgccg gctcggcggg
    17401 cagcgggtcg ccgctgctgt cggccgagcg cagcaggtcc cagacccgcc gtaggcgggg
    17461 ggcggagccg agccgggtgt ctccggcgag gaccgcctgc cacagcgagg gcaggagagc
    17521 cgcgaccgcg gtcatcttgc gggcgccgag cgcgctggac agttcgttcg cgatcatcca
    17581 gccctcggtg ctgaacaggt ctcggccgta ggagaaccag gtggactggg tgagtccgct
    17641 gagccgggcg aggtcggtcc gcagttcggc gccgggcatg cggcccgccg cgagctgccg
    17701 ggcggcttcg ccgcccagcc ggaccagctg ggtcgccgcc gcctcggaga gggcgtcctc
    17761 gaccgggcgg tccaggaggt tgccgatgta cgggccgatc gtgcggaaga gggcctccag
    17821 cacgccttcg accaggaggt ccgccggcag tgtctcggtc gccgaggggt cgagcagggc
    17881 cgcgtccggt gccagtgcgt cactcatcac gagccgcttg ccgctgttgt gcgggaggca
    17941 ggcgacccgg ctgagttcgg cgccggtgcc gatggtggtg ggtaccgcca gcagaggccg
    18001 tgacctgcgg gtacgcggat cgagggtcag cagcccgctg cggccggtgg tgcgcagggc
    18061 ggcgcgggcc cgtgggtcct cgtgggcgac cgcgagcagc ttcgcccggt cgatcaggga
    18121 tcctccgccg acggccgcga tcaggccggc gtcggcggtg gcgccggcca gggcgaggat
    18181 ctcgtccggg ccgccgtcgc cgtcggggac gatacgccgg acggtgtggc ccgcccggtc
    18241 cagttcctcg gtcaccaggg cggtgacgga gctctcggcc acggccgggt cgagcagcag
    18301 ggcggtgccg gcggggccgg agtctccccg ggcgtcctcg aagtcctcca gccagtcggc
    18361 gagccccgcg gagccgacca gcagccgggt ggaaccggac caggcgatgt tcaccggatg
    18421 cctcccgcga agtgctcgac accggtgcgt acggcctcga ccagttcctg gatctcggcg
    18481 tcggtcgcgg tgagcggcgg catgatctgc acaccgtgga caccggcgtg gacgatcgcc
    18541 cccgccgcgc ggatggcggc gatctggccg agcacctcgg cctgcggcag gagcccgccc
    18601 ccggccgtac ggatccgcag cgaccggaag agcccgcggc cgtcggcgga gtcgaacagg
    18661 gggtgcccct cgacgagccg gtccagagcg gtgccgagca cctcggcggc acgccggccg
    18721 agggccaccg cgtccagccg ccgcatctcc tcgatggtgg cgaggatcgc ggcacaggtc
    18781 accggggtgc ccgcctgcgt ctcgccgtgg gtgagcgtgg cgtcctcgtc gcggaagacg
    18841 tcggccacct cgcgggagac gaccacggcc gcggcggcgc aggtcccgtt ggtcagcccc
    18901 ttggaggtga ccagcagatc gggccggccg ctccagcgct gggaggcgaa catgtccccg
    18961 gtgcggccga acccggtggc cacttcgtcg gcggcgagca ggaagccgta ctcgtcccgc
    19021 agcctcagca gggtgtcgac gtactcgtcc gtgaggggta cggcaccgct gccgagcacc
    19081 ggttcgacca cgacggcggc cacctggcgg ccctgggcac gcatcagctt ctcgatgtcg
    19141 cccgggtcgt tgggggtgac atggcggacc aggcgctggt cgacgccgta cacctgctgg
    19201 ccgaggttct ccccggtgag ggcgaacccg ccgaaggtga gcccgtggta actgccccgc
    19261 agcccgacga cgatcttgcg ggacgcctgt cccctcagtg cgtggtagtg ccgggccgtc
    19321 ttcatgacca ggtcgttggc ggcgcccccg gaggtcgaga acagcacccg ggcgaagtgg
    19381 tcggctccgc agagcgcgac cagggcctcg gcggcacgcc gggcgtaggt gtgctcgtag
    19441 cggaagacgc tcaggtacga ggcgtcgcgg agcgcttcgt aggcggcacg ggcgatgttc
    19501 tcgttgccgt ggcccagatt ggcgttccac agcccggagt caccgtcgag gagttcgctt
    19561 ccgtcggcga aacgtacgcg catgccctgg gcggagacgg cgcagatgct gtcgtcgccg
    19621 tgggcggagg gagggagcag ggaggtccac agcgcggggt gggaccgcgt gccggcctct
    19681 tccggcaggg gtgtcagggt cgtctcggtc atcacagggc ctctgcttcg agcaggacgt
    19741 cgtggtggcg tccgccaccg ggtacggggg tgagggagcg gacggcgtaa ccggcctgct
    19801 ccagctcggc gatgagccgc tgtgcgggca ggacgccgat ggtggtggtg gcgaccgtga
    19861 cggggccctc ggcgggcggc tcggccggga tcatggtgac cgtgcgggtg gtggcgcccg
    19921 cgctccactg ctcgatcatg cggtaggtac ggccgctctg gccctccgcg aggatctcgg
    19981 actcgtccgt gccgtcggcg gccggatcga cctcgaccgt ggtgatcagg aagcgtccgc
    20041 cgggggcgag gtgctcccgt acacagcggt agagaccggg gcgggcctcg ggcggcagca
    20101 gcgagaccga ggtggtgccg agcaccacgg caccgaaacg gcggccgagg gcgaagtcgc
    20161 tcatgtcggc ccgcaccggt gtgcagcgtc cgcgcagcga gggcggggtg gcggccaggc
    20221 gctcacggag cagcccgatc atgtcctctg acagttccag ggcggtgacc tcgcggccga
    20281 gaccgaggaa ggggaaggtc aggcggccgg agccggccgc caggtccagc accgggccgg
    20341 gcagtctgcg cagggccgcg aggagttcgc gtacctcgtg cggggtggtg ccggcgatgt
    20401 cgtggtagac gggggctccc gcctcgtcgt acaggtcgca caggacggcc tgttctccga
    20461 gcccggcgac ggcctcggcg gcgcggccgg tgagcggggt gcccgcgagg gcgggactga
    20521 gcagcatggc gcccatcagg cgttcacctc ctcggtgacc gtgcggggct cggcggattc
    20581 ggtgaggggc aggccgatgc cggcgaagta ggcggcgacg gcgtcgacgg tgtccggggc
    20641 ggcgtaccgg gcggcctcct gagcggagcc cgtgaccagc agcgcctcgg cggcgagggc
    20701 cgcgtcggtg gagagggcga cggtgcggcg gtccacgggg tggtggatca gggcgcgttc
    20761 gccgttgtgg aggagcagcg gggcggtggc ggaccggtcg aagggctcgg cgaagccgtt
    20821 cagcgcctcg gtcatgcggc cgccgaaccc ggagacgcgg ggctgttcca taccgcgggt
    20881 cacggcctcc ctgaccgcgc ccagagccgc caggtaacga ccggtccagg gacgggaggc
    20941 cagctcccgt gcccgggagg cgctgtccgg caccgctccg agtgcgtcgg ggaactcctg
    21001 ccacgcgcgg tgcagttcgt cgcgcggggt accgacgggg ccgagcgggg cgccaccggg
    21061 ggagacgctg acggtgccgt cggcggccac gtacagccgc aggccgggtc cgtcctcccc
    21121 ggggccgccg cccagcgcgg agaggtcccc gagctgtacc gcgggatggg tgaggtattc
    21181 ggagaactcg ccctggtcca gcgcacgtcc ggcgtcgtcg aggtaggcct ggaagtcggc
    21241 ctcctcggtg atccggacca gcgtcggacc cagcaccgag aggtaggggg tgatcgagta
    21301 ggcctgcacc tggaggtaga agtcggggtg cagccccgcc tccgcgccgg gctcaccgag
    21361 cgagccctgc caggtgatga tctccgcgcc ggtcggctcg tggcgtacgg gttcggcgct
    21421 cggctcgtcc ccggggacga ggacggtggt tccggggccg gccacacccg agccgagcag
    21481 ggcgtcgagg tgggacgcgt cctccaggac gacggtcgag gtgtacggcg gacgggcgga
    21541 gagggcggac acgggacgtc ccgtgcccca ctgcaaggcg tgggccttgg ccgaagaatg
    21601 tgtcatgagc atgcctaacg tgagtgcgtg aggagccgac ggcagggggc tgcctgcgaa
    21661 gtccgggtgg tggagcgcgt acgtgcgaag tccaggggac gcggggaggt acccgcgagg
    21721 agggcggccg ggtctgccgc gaggtcagac ggccaggccg agcagggtca gcagggcgcg
    21781 cagctccttg gtggccgcct gtggcccgaa gacccgggcc acaccggtga cgttgaggac
    21841 gatctcgtcg acccccgcct cccggtaggc gtccagcccg gcccgcagcc cgtccggtcc
    21901 gccgtacagg aaggcgtcgc cggcgatcag tgccttgccc tgcaggagct cgttgtcgtc
    21961 gggcggtccg gtgccctcgg gaacctcgtc cggcaggtcc acaccgccgc gccggagcat
    22021 gtcgcggtag tgcgccgcac gcagatggtt ccggttcgac gcgagggcga gctgcacggg
    22081 gtcgcggtcg tgggcctcca gggcgagggg caccatggcc accacacggg gggcgggccg
    22141 tccggtcctc tccgcgctct cccgtaccgc gggcacgatg tgctcccgca gataacgggc
    22201 gggcgtcagc caggtgatgg ccgcgtcggc cacctcgccg gccacccggg ccatcccggg
    22261 ccgcagcaca ccgagtccga gctcgacctt cgggccgggc acgggccgca gcagcgactc
    22321 ctggtgcacg tacgtaccgt ccagcacctc cggacccccc gccagcgcgg cacgtacggc
    22381 gcccaggtac tcgcgggccg cggtgagcgg actgcggtac ggggcaccga gcagtgcctg
    22441 ctgcacaccc ggggctccgg ggccgtaccc cgccaggacc ggttcgccgg tcatcaggga
    22501 gagcgatcgt gcctggagcg cggcctcggt gggatgccgc aggggcatca gggtcactcc
    22561 gagccccgcc ggcacccgga atcccgcacc ggcggcgtag gcgaacccct ggtgggactc
    22621 ggtggagagg ctctgcccct gccacagccg gtgggcaccg gtccagtgca cgagtcccgc
    22681 gaacggcagc atctgctcgg gtctgctcgg ga
//
