LOCUS       NZ_CP023702            24885 bp    DNA     linear   CON 23-APR-2024
DEFINITION  Streptomyces nitrosporeus strain ATCC 12769 chromosome, complete
            genome.
ACCESSION   NZ_CP023702
VERSION     NZ_CP023702.1
KEYWORDS    RefSeq.
SOURCE      Streptomyces nitrosporeus
  ORGANISM  Streptomyces nitrosporeus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 7581562)
  AUTHORS   Lee,N. and Cho,B.-K.
  TITLE     Direct Submission
  JOURNAL   Submitted (27-SEP-2017) Biological Science, KAIST, 291 Daehak-ro,
            Daejeon 34141, South Korea
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. 2.3
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 50X
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008704555.1-RS_2024_04_23
            Annotation Date                   :: 04/23/2024 03:20:47
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,704
            CDSs (total)                      :: 6,606
            Genes (coding)                    :: 6,461
            CDSs (with protein)               :: 6,461
            Genes (RNA)                       :: 98
            rRNAs                             :: 6, 6, 6 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 6, 6 (5S, 16S, 23S)
            tRNAs                             :: 76
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 146
            CDSs (without protein)            :: 145
            Pseudo Genes (ambiguous residues) :: 0 of 146
            Pseudo Genes (frameshifted)       :: 66 of 146
            Pseudo Genes (incomplete)         :: 106 of 146
            Pseudo Genes (internal stop)      :: 16 of 146
            Pseudo Genes (multiple problems)  :: 38 of 146
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 11:19:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 947661
            Orig. end                         :: 972546
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP023702.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            Bacteria available from Korean Collection for Type Cultures.
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..24885
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="False"
                     /product="terpene-precursor"
                     /product="butyrolactone"
                     /region_number="5"
                     /rules="(PT_FPPS_like and not PT_HPP)"
                     /rules="AfsA"
                     /tool="antismash"
     cand_cluster    1..24885
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_FPPS_like and not PT_HPP)"
                     /detection_rules="AfsA"
                     /kind="neighbouring"
                     /product="terpene-precursor"
                     /product="butyrolactone"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    1..24885
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:14885]"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..14885
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(PT_FPPS_like and not PT_HPP)"
                     /neighbourhood="10000"
                     /product="terpene-precursor"
                     /protocluster_number="1"
     gene            333..1355
                     /locus_tag="CP967_RS04215"
                     /old_locus_tag="CP967_04245"
     CDS             333..1355
                     /GO_function="GO:0051920 - peroxiredoxin activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF014664.4"
                     /locus_tag="CP967_RS04215"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04245"
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="WP_208838858.1"
                     /transl_table=11
                     /translation="MGSAGHDDGFGGLYARGRETFAGLLPDGGERLDAIFALSPGLAHV
                     AVGTVYGYLHHRRALDARAREIAALAAIVSSGMCGTPLAVHTRSALAAGVAPAEIVEVV
                     VECAAFAGFPRAVSALPAVEKVFAEAGIASPPQRSPREVVLEALDTARRRTATDGRGPE
                     DEPFAPALRPGSDTTVYTLAPDRALVLCAPAGPVDGEGEILDIRVVDGRVAGTTVLTES
                     ASAAGPAGARETAGAARHALTAFLRDLDAVGHGPAAEFVLGGPDLLDDTAPLLGPLAAG
                     IRPRVYGLGEECAAAVFEDAGPSGPVIALAFCEGGRVRSLRVAGDDRAGAGPGPGLRDG
                     "
     gene            1379..2050
                     /locus_tag="CP967_RS04220"
                     /old_locus_tag="CP967_04250"
     CDS             1379..2050
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012360.4"
                     /locus_tag="CP967_RS04220"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04250"
                     /product="transferase hexapeptide repeat family protein"
                     /protein_id="WP_150486634.1"
                     /transl_table=11
                     /translation="MPLYAFEGRFPEIAPTAFVHPDSVLTGDVLVGGHCYLGPGASLRG
                     DFGRIVVGEGANIQDNCVLHCFPGREVRVGADGHIGHGSVLHGCRVGPGVLVGMNAVVM
                     DDAELGAGAVIGAGCVVPAGMAVPERHLVVGVPAKILRELTADELEWKARGTATYQELA
                     VRCVTGLSTVRPKSGPPPGDSPAHVAGWRHVPLHDHRAGASATEATGTPAPPDGPGRDL
                     G"
     gene            2108..3220
                     /locus_tag="CP967_RS04225"
                     /old_locus_tag="CP967_04255"
     CDS             2108..3220
                     /GO_function="GO:0004664 - prephenate dehydratase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009094 - L-phenylalanine biosynthetic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012998.4"
                     /locus_tag="CP967_RS04225"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04255"
                     /product="prephenate dehydratase domain-containing protein"
                     /protein_id="WP_167535323.1"
                     /transl_table=11
                     /translation="MIHQPSPSGHHRRQKVIDDVDTRLIRLIGKRRAVSEEVRNDRLAE
                     GGTRTDTGWEMHVISRYHEAFGSPGRDIALGLLRLSQGEPPTGRPSAPDAFLGPADSYS
                     GVAHRQFAGSGGPVLLMDSAADVLDAVGRGRAGSGTVPVHNTTAGPVVEVMDALALGAP
                     LSVIGERRLPVTLVLATVRPGPPDGVRVVRTHPHAYAQCASWFAAHLPGARCAAAPSTA
                     AGAETVAREGDASRAALCAPATAERLGLHPVGGNLTGTPPAVTRFLRVVRVAPPRPPTG
                     RDLTTLVVPADRVPLLTVVRSLAASGVHVQDLHPGGRHPDGYLWIDVAGHRDQAPLGEA
                     LERLRRESDRVRVLGSYPAASARAVSGETL"
     cand_cluster    2348..13271
                     /candidate_cluster_number="2"
                     /contig_edge="False"
                     /detection_rules="AfsA"
                     /kind="single"
                     /product="butyrolactone"
                     /protoclusters="2"
                     /tool="antismash"
     protocluster    2348..13271
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[7347:8271](+)"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      7348..8271
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="AfsA"
                     /neighbourhood="5000"
                     /product="butyrolactone"
                     /protocluster_number="2"
     gene            3334..4671
                     /locus_tag="CP967_RS04230"
                     /old_locus_tag="CP967_04260"
     CDS             3334..4671
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012377441.1"
                     /locus_tag="CP967_RS04230"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04260"
                     /product="hypothetical protein"
                     /protein_id="WP_150486636.1"
                     /transl_table=11
                     /translation="MPRTPNERLRTLVRRSGWSHSRLAQAVRLVAAEHERPVLCDHTSV
                     SRWIAGTQPRPPTSTFLLEALSRKLGRRITAQEAGLTRAPAAPLVLSWQDDSLHRLDRL
                     VEFELDPARVHLLEAGTYRPSALLPPDPWSPLGSPAANPEPVTGRVGGAEVAQLRSLTE
                     LFALSIAQHGGQAIRPALAAYLAHTVTPWLRAPSSDTTRRELLAAGAQLTLLLAEACID
                     ADGHAATQHYQQLAVRLAAGSGDHATVAIALRAMATHATGLGHRGPAVLHLTQRAVEHA
                     RHAPPAVRSYTYAHLAVVQAHHDRRAALDALARAERFHTEGADAPPGPFTSYPEGALHY
                     QRAQTLDALKNTPGALLALNASLRARTPGEHRAALLTHARLAGILLRHGHLERALAHWQ
                     VFVDEYPTLRSPRTHRMLKAMHGQLRPHGRHPGARDLLARADVLLR"
     misc_feature    4399..4401
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            complement(4924..5766)
                     /locus_tag="CP967_RS04235"
                     /old_locus_tag="CP967_04265"
     CDS             complement(4924..5766)
                     /NRPS_PKS="Domain: PKS_KR (13-181). E-value: 2.7e-08.
                     Score: 25.9. Matches aSDomain:
                     nrpspksdomains_CP967_RS04235_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010353708.1"
                     /locus_tag="CP967_RS04235"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04265"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_150486637.1"
                     /sec_met_domain="adh_short_C2 (E-value: 2.2e-35, bitscore:
                     121.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSVLDRFRLDGGRALVTGASRGIGKAVAEALAEAGCDVAVAARTL
                     PALRSTVAAVEERGRKAVALDGDLALPEVATGLVERAAAGLGGLDVVVLNAGVLPHGED
                     GAVLLEPLHRADPEDWNSVIAVNLSATAALAGAAHDHLVSSGRGSLILMSSIAGVASLP
                     ALEAYGAAKAAQLSLVRSLAVGWARQGVRVNAVCPGWTRTDMTAFATGYGALSDWLTSH
                     VPLGRWATTDEIAGATLFLASPAASYVSGHALFVDGGITVPEIGLGGFPKPASPLAGG"
     aSDomain        complement(5224..5727)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP967_RS04235_PKS_KR.1"
                     /evalue="2.70E-08"
                     /label="CP967_RS04235_PKS_KR.1"
                     /locus_tag="CP967_RS04235"
                     /protein_end="181"
                     /protein_start="13"
                     /score="25.9"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALVTGASRGIGKAVAEALAEAGCDVAVAARTLPALRSTVAAVEER
                     GRKAVALDGDLALPEVATGLVERAAAGLGGLDVVVLNAGVLPHGEDGAVLLEPLHRADP
                     EDWNSVIAVNLSATAALAGAAHDHLVSSGRGSLILMSSIAGVASLPALEAYGAAKAAQL
                     SLVRS"
     CDS_motif       complement(5659..5724)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_CP967_RS04235_0001"
                     /evalue="2.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="CP967_RS04235"
                     /protein_end="36"
                     /protein_start="14"
                     /score="16.8"
                     /tool="antismash"
                     /translation="LVTGASRGIGKAVAEALAEAGC"
     gene            6130..7206
                     /locus_tag="CP967_RS04240"
                     /old_locus_tag="CP967_04270"
     CDS             6130..7206
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057157.1"
                     /locus_tag="CP967_RS04240"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04270"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_150486638.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 1.1e-08, bitscore:
                     34.3, seeds: 790, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEDEQDHPLLVRARRLSEVLLAPAAQRVDQDGLPAAHLDELRASG
                     LLGASAPQAYGGAGVPDAVARDIQEALATGCCTTWFVQAQHQSPLRLLAASDSPAKERL
                     LPELASGRVMAGVAYAHVRSFPRVPVRATADRGGWRFDGTVPWYTGWKLNDVMLLAGID
                     ADDEVVFAFTEAGGQPGLRASEPLRLVAVSSSRTVSLRLDGLWVPPESVVLRVPRERWA
                     VTDLAHASHVSPAVFGVAEAALRLLEETGAEAAATARGLRAELALVRRHAYALADRPEP
                     DHGVPERTALRLRALDLLRTVTTAVVVAGGGRTTGLDHPAQRLARESLFLLVQGQTAPV
                     RRAHLASLAPGPGAAAPP"
     gene            7348..8271
                     /locus_tag="CP967_RS04245"
                     /old_locus_tag="CP967_04275"
     CDS             7348..8271
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     butyrolactone: AfsA"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF015700.4"
                     /locus_tag="CP967_RS04245"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04275"
                     /product="AfsA-related hotdog domain-containing protein"
                     /protein_id="WP_167535324.1"
                     /sec_met_domain="AfsA (E-value: 7e-07, bitscore: 27.8,
                     seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAAQAGVGHPGDVLLVHDAVLPNGLSFRVRVPGAHDLFGDRGSG
                     GLPDDAFLLRSVVEQCAYATLQHTGLLRPGEVPLNTSSSSRVLTAPPLRRFQGELLATC
                     LVEQLRTSRTGRTRRVAASCVLRSPDGRVVADGETGAGVLERALYRAWRGAGVVRAGNL
                     PPVQDGARARTGRVRSLPGNQVLARAGREDGGDAHAVLRLSGPHPYLLPASADHVTGRL
                     FAEAARQLVLGVCGPYTGLRALHLSFLRLCTLEESVRVRAVPCSGPRASDRWRVLFSQA
                     GATVCAGHVEADVPEGRERRTRHRDG"
     gene            8572..9807
                     /locus_tag="CP967_RS04250"
                     /old_locus_tag="CP967_04280"
     CDS             8572..9807
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014140476.1"
                     /locus_tag="CP967_RS04250"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04280"
                     /product="cytochrome P450"
                     /protein_id="WP_150486640.1"
                     /sec_met_domain="p450 (E-value: 2.1e-15, bitscore: 55.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAHEPVSRCPVLDVSGRSLHADAAALRSEAPAVRVLLPGGVTAWA
                     VTRYDVIRALTSDPRVSRDFARHWPGRSEVPDGWPLAAVTFQQNFLNTYGAEHRMLRGL
                     VAPSFSPRRVSAMRPGIEAVAERLTNAWAALGPGEATDLRATYALPLTMTVICELFGVP
                     EHLRGPLGAAIDRAADTAASPEQALAVHAEIDARLDELVSHKRAHPGADLTSDLLMNPA
                     EDGSVFTEETLKGTLFLMIGAGYETTVHLITSAAHALLTGPDVVTRIRKGELRWADVVE
                     ETLRLQGPIMYLPLRYAVEDIDLGEGVLVRQGDAIAVAFAAAGRDPDRHPKGPDDFDPS
                     RADKTHLAFGHGPHFCLGAHLARLEAEVALRTLFTRLPRLALASPERTPDRLPSFILNG
                     LTGLPVVPVPAA"
     misc_feature    complement(9928..9942)
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: medium, score: 18.29"
                     /tool="antismash"
     gene            10001..12301
                     /locus_tag="CP967_RS04255"
                     /old_locus_tag="CP967_04285"
     CDS             10001..12301
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF012568.4"
                     /locus_tag="CP967_RS04255"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04285"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_150486641.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 7.3e-49, bitscore:
                     165.0, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNQTAPDMPAPPVRAPKGGVPLHLAALSDGGADPDAAHDDAGME
                     WWYVNLHLVTGAGEPLSVFAAFFRIGERDDEGGVSYSHTLAAAWSEPRTRRYTPLSCVD
                     DANLTLIRKVLHHDRAYAPRLREALRHLVSADRPPLPDLPLEGEPAVRAVPFAVDYGPQ
                     GSLGRDPRGRYRLRLRHPGRPFALDCRLTPVRPAAWQGGDGTVAGLGESGEGMRYYSVT
                     RLEAEGTVTVDGAAHTIASGSAWYDHEWGLDPISPERGYTHDEPEWDWCGLHLDDGQDL
                     SVSSWRRSDRRSATGRTVDRTSLLVSPDGAAGTLDDWRFEPLERWTSLATCNTYPVAWR
                     LTAPSHGVDLELTAAFAEQEVRTITVHRGFWEGRVEVSGRAGGRPVTGRGFVEVKPAQV
                     LPRIDPLMDTIGAETRAQVALLYPAAASPSTTESLLGPIAPDLLAVLPHESLHRALMAP
                     VGHTVGGIGKSWRSFALVAVLEALGVSSDPYRPLLAAVELLHTGSLMVDDVQDAAVLRR
                     GRPAAHTVYGEATALNAGTAAYFVFDRVLRALVLSDADRLRTYEILCAMLRCAHAGQGL
                     DLTRDWADGPGPDPALLGERVLAVHRLKTALPVRALAEIGAALGKAGPAQEAALCDYFE
                     ALGLGYQIADDVWDLKGHRAAAGELRKEPGEDIRNGRVTYPLVCALELLPGPDARWLWE
                     RVRGRPQDRAEIHACVRAITGCGALELALSRAEERLDRAWEVLEPLLPPYPVVALLRSL
                     GFYAVTRDAELNG"
     gene            12714..13778
                     /locus_tag="CP967_RS04260"
                     /old_locus_tag="CP967_04290"
     CDS             12714..13778
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012378389.1"
                     /locus_tag="CP967_RS04260"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04290"
                     /product="lipoate--protein ligase family protein"
                     /protein_id="WP_150486642.1"
                     /transl_table=11
                     /translation="MHGEYKVPGGKLVVVDLDVEDGVLRDVRVAGDFFLEPDEAILSIN
                     AALEGSPASTDTAGLAARITAALPESTVMLGLTAEGVGIAVRRALARATEWSDYDWQLV
                     HMEPQAPALHMALDEVITAEVAAGRRAPTLRVWEWASPSVVIGSFQSLRNEVDPEGAAK
                     HGMTVVRRISGGGAMFVEPMSTITYSLSVPESLVTGLSFADSYAYLDDWVLGALGDMGI
                     KAWYQPLNDIATEAGKIAGAAQKRVVGPDGGPGAVLHHVTMSYDIDADKMLEVLRIGKE
                     KLSDKGTKSAKKRVDPLRRQTGLAREQVIENMIASFRNRYGLTTGAVTPEEMARAEELV
                     RTKFATEEWTARVP"
     gene            complement(13809..14885)
                     /locus_tag="CP967_RS04265"
                     /old_locus_tag="CP967_04295"
     CDS             complement(13809..14885)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene-precursor: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007389575.1"
                     /locus_tag="CP967_RS04265"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04295"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_150486643.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 6.8e-42, bitscore:
                     142.1, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTQQMAALERVAGYERRFNALFEEYFDRLGTTLDTPASSRFTPDC
                     LRLLRELSLRGGKRMRVALLHEAARLVTDRPVAGLDAAALSVELLQTHGLVHDDLIDDS
                     PTRRGGPSTYYAYRAQFPDHPGAALGLTVLAGDLAFALSLRVLHDADLPAAVRQEMAEV
                     QTRAAADTFMGQIIDLERDFAPSPDEDLLHRVADYKSARYSLLAPLWLGLLAAGERPAA
                     YEDELRRYARLVGICGQMRDDYLDLFGDPAAMGKPTGTDIRDGRRSYTVVALLSAVSGT
                     ERAVVEAALGDPSGTPETLAALRDIAEERGVAAGLRDEMRRHAEQASRVAAGWRPRWRE
                     EAVSFFEHLPLWSVERAG"
     gene            complement(15116..16417)
                     /locus_tag="CP967_RS04270"
                     /old_locus_tag="CP967_04300"
     CDS             complement(15116..16417)
                     /NRPS_PKS="Domain: Abhydrolase_1 (52-249). E-value:
                     8.6e-17. Score: 53.5. Matches aSDomain:
                     nrpspksdomains_CP967_RS04270_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544577.1"
                     /locus_tag="CP967_RS04270"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04300"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_150486644.1"
                     /sec_met_domain="PF00561 (E-value: 5.4e-16, bitscore: 57.6,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTPPLVSYRHGGLVCTDHTLDVPLDHRTPGSGTLGLFAREVVAE
                     GREHEDLPRLLWLQGGPGGRAERPNAAGAWLRRALEGHRVVLMDQRGTGRSAPVDRRTL
                     ARFGSDHAAAAGHLGHFRADSIVRDAELLRRHLQGDRPWSVLGQSFGGFATLTYLSLAP
                     EGLSQAYITGGLPTLTGHADDVYRAAYARTLAHNERYFARYPGDQALAAAVAAHLDAHD
                     VRMPTGERLTVRRFQTLGITFGTSAKFDSLHYLLETAFTDGAAGPELTDTFLRGVEATV
                     SFAERPLYAALHEPIYAQGARATDWSAHRIREEFPAFDAAPGTPLRFTGEMVYPWQFEE
                     DPALVPLRGAAGILAARTDWPALYDLDRLAANEVPVVAAVYHDDMYVDREHSLATADAV
                     RGLRTWVSRDHAHDGVRADGAVLDRLLAMARGDI"
     aSDomain        complement(15671..16261)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_CP967_RS04270_Abhydrolase_1.1"
                     /evalue="8.60E-17"
                     /label="CP967_RS04270_Abhydrolase_1.1"
                     /locus_tag="CP967_RS04270"
                     /protein_end="249"
                     /protein_start="52"
                     /score="53.5"
                     /tool="antismash"
                     /translation="PRLLWLQGGPGGRAERPNAAGAWLRRALEGHRVVLMDQRGTGRSA
                     PVDRRTLARFGSDHAAAAGHLGHFRADSIVRDAELLRRHLQGDRPWSVLGQSFGGFATL
                     TYLSLAPEGLSQAYITGGLPTLTGHADDVYRAAYARTLAHNERYFARYPGDQALAAAVA
                     AHLDAHDVRMPTGERLTVRRFQTLGITFGTSAKF"
     misc_feature    16535..16548
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 19.73"
                     /tool="antismash"
     gene            complement(16636..17694)
                     /locus_tag="CP967_RS04275"
                     /old_locus_tag="CP967_04305"
     CDS             complement(16636..17694)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544576.1"
                     /locus_tag="CP967_RS04275"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04305"
                     /product="hypothetical protein"
                     /protein_id="WP_229888387.1"
                     /transl_table=11
                     /translation="MYSRLEPRPEYLSFELALAARKLVEEVMLVKRGEHVVLTGDTSSD
                     RRVVEATAQAVAAAGAHPVIVWYETMPGASMEPPRPVAGAIADADVWIEFAVSYVMHSD
                     AFRAAMANGCRYTNLTAMDVQMLVATVGRPDFQGVIRLGKALVALLEAADEVRITSANG
                     TDLVGRNGDRPINLRGKPAEKPGETVMLSGQISWNPLEETQDGVLVFDGALWPPDEIGL
                     LRSPVRCTVEKGVVTKIEGGADADTFRRWMESFDDPNMFRIAHWSLGFNPGVLAPTGRI
                     VEDERVFGCVELGIGTKGAWIGGEPWVAAAHTDGSVLGPSIYLDGVAIEENGRYVHPEL
                     VEICRELGVAGY"
     misc_feature    17685..17703
                     /note="TFBS match to LexA_variant_3, Repressor of DNA
                     damage response, confidence: weak, score: 20.12"
                     /tool="antismash"
     gene            complement(17764..19344)
                     /locus_tag="CP967_RS04280"
                     /old_locus_tag="CP967_04310"
     CDS             complement(17764..19344)
                     /GO_function="GO:0035673 - oligopeptide transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019435403.1"
                     /locus_tag="CP967_RS04280"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04310"
                     /product="OPT/YSL family transporter"
                     /protein_id="WP_150491695.1"
                     /transl_table=11
                     /translation="MLLVILVVLAAVGAVIGIDLVSKLGISANTSVVGALVAMLIGRIP
                     LGFLRRMRSVHRQNLAQSAISAATFASANALLTSVAIPYVFGRQDLVWPMLAGSFAGLL
                     VDAWVLYRAFGSRLLPADAAWPPGTAAAETIKAGDKGGRRALVLAGGTAVGLAGTLFSL
                     PLSAAGVAFLGNVWALMMFGVGLMLRQYSPDLFGTDLGSGFIPHGVMVGAGIVALGQAV
                     HMLMGRRARTRNKPPREPASTLAVPEPDPTTAYTVDERGLRLALIRGYALFTAGAVLLA
                     VLGGLIGDMSPLGIVGWVLFAAFAALVHELIVGLAAMQSGWFPSFAVTLIFLVLGLAMG
                     IPSVPLALLIGYVSATGPAFADMGYDLKAGWLLRRDHRPWDPYEREGRRQQFLAALIGF
                     GVALAVVAVAWRSYFGQGLIPPVAKVYADTIKSGLSDPDAVRTMLLWAVPGAAIQLIGG
                     TRRQMGVMLATGLLILTPQACWLVLGALAVRIGYRKLRGPAADEELNLIGAGVIAGSSL
                     GDSAQILKT"
     gene            complement(19563..20360)
                     /locus_tag="CP967_RS04285"
                     /old_locus_tag="CP967_04315"
     CDS             complement(19563..20360)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1195: IclR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019544574.1"
                     /locus_tag="CP967_RS04285"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04315"
                     /product="IclR family transcriptional regulator"
                     /protein_id="WP_150486646.1"
                     /transl_table=11
                     /translation="MADHGGDTPQAGSPPQAPGVLQTVDRALVVLLTFTEQRPEWGVSE
                     LSRHHGWDKAVVQRLLTTLAARGFLLCDSTTRRYRPGPALSRLARVSEYSGVLPSLARP
                     VLARMLRETGESVVLNVPHGAGYRCAAAVDGTGPVRYTAIIGAVMPGHAGASGHAIFAH
                     HPEREIRQMFGPTGLARFNDRTITDLDALFTCYARVRADGHCVSYGEYDEAVTAVSAPV
                     LQGGAVAASLTVIGPSHRVDRAVGTLVPLVRAGAAEVTAALGG"
     misc_feature    20494..20508
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 17.14"
                     /tool="antismash"
     gene            complement(20909..23128)
                     /locus_tag="CP967_RS04290"
                     /old_locus_tag="CP967_04320"
     CDS             complement(20909..23128)
                     /EC_number="1.1.1.42"
                     /GO_function="GO:0004450 - isocitrate dehydrogenase (NADP+)
                     activity [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579449.1"
                     /locus_tag="CP967_RS04290"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04320"
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="WP_150486647.1"
                     /transl_table=11
                     /translation="MTDSTIIYTHTDEAPALATYSFLPVVEAYASTAGVSVESRDISLA
                     GRIIASFPERLKADQRIDDALAELGELAKAPGANIIKLPNISASIPQLKAAIAELQAQG
                     YALPDYPDDPKNDEDKDVRARYDKVKGSAVNPVLREGNSDRRAPASVKNYAKTHPHRMG
                     AWTADSKTNVATMGVDDFRSTEKSAVIAEPGSLRIELAGDDGTTTVLRESVPVLAGEVV
                     DASVMRVAALREFITAQIARAKAEDVLFSVHLKATMMKVSDPIIFGHVVRAFFPKTFAE
                     YGETLAAAGLTPNDGLGGILKGLEALPDGAKIKASFDAELAEGPALAMVDSDKGITNLH
                     VPSDVIVDASMPAMIRTSGHMWGPDGQEADTIAVLPDSSYAGVYQVVIDDCRANGAFDP
                     STMGSVPNVGLMAQKAEEYGSHDKTFEIPATGTVRVVDAAGNAVLEQAVGAGDIFRMCQ
                     TKDLPIQDWVKLAVTRARATGSPAVFWLDEDRAHDAQLIAKVRTYLADHDTDGLQIEIM
                     TPQEATAFSLERIRRGEDTISVTGNVLRDYLTDLFPILELGTSAKMLSVVPLMNGGGLF
                     ETGAGGSAPKHVQQLVKEDYLRWDSLGEFLALAVSFEHLAQTTGNARAQVLADTLDRAT
                     ATFLNEDKSPSRRLGGIDNRGSHFYLALYWAQELAKQTDDAKLAEAFGPLAKTLGEQEQ
                     TIVDELIAVQGKPADIGGYYQPDPAKAAAVMRPSATFNEAIASLG"
     gene            complement(23228..24760)
                     /locus_tag="CP967_RS04295"
                     /old_locus_tag="CP967_04325"
     CDS             complement(23228..24760)
                     /EC_number="3.5.1.4"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1105: amidase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018514768.1"
                     /locus_tag="CP967_RS04295"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="CP967_04325"
                     /product="amidase"
                     /protein_id="WP_150486648.1"
                     /transl_table=11
                     /translation="MSSADPVGRTGPHGRKQRPDTPAEAAGLVDAVRQLAGGHTSSTAL
                     VAAALSRIEAADPTLNAFRHLRAEAALAEAAEADRRLASGERLPLLGVPVAVKDDTDVA
                     GMPTYFGCDGALPPATADGEAVRRLRAAGAVVVGKTNSCELGQWPFTEGPAFGATRNPW
                     DTTRTPGGSSGGSAAAVAAGLVPAALGSDGAGSIRIPAAWTHLVGIKPQRGRISVHPNS
                     DAFQGLTVNGPLARTVADAALLLDAAAGPHPGDPHRPPAVDASAAARRDPGRLRIGLAL
                     RPPLTLTRNAPHPEVVRAVTALAEALARLGHHVEEARPRYGLIGLSFVPRATAGIAELA
                     AAHPEPALLDPRTRSALRTGTRLGGRVVRAARAREVRQHRRIGAFFDPYQAGHGGGRGY
                     DVLLTPTTAAPPPRIGAFDGLSAWRTDLAITAACPYAWPWNVLGWPGVNVPAGFTQDGL
                     PLGAQLLGPSRSEARLISLAAQLEADRRWYERRPPATGTPATAGEGGPPGAE"
ORIGIN
        1 ggcgcggcag atgctgctcc tcgcggagcg cgtcgacgcg tccaccgctc tcgcctgggg
       61 cctggtcaac tcggtcgtcg agcccggcgc ggtggtgagc accgcgatcg aatgggcacg
      121 caggtgctgc gccctctccc ccaccgctct gggagtgctc aagcactcgc tgaacgccga
      181 cacggagcac atcgcggggc tgggccgggc gtgcttcgac accctgagcc tgttcgggca
      241 catgccggaa gccagggagg ggtacaccgc cttcgcggag aagcgggtgc ccgacttcag
      301 cgggttccgc accggcacgg cggtggacgg ccgtgggtag cgcggggcac gacgacggct
      361 tcggcggtct gtacgcccgg gggcgggaga cgttcgccgg actgctgccg gacggcggcg
      421 aacgcctcga cgcgatcttc gccctctccc ccggcctggc ccacgtcgcc gtcggcaccg
      481 tgtacggata tctccaccac cgcagggcgc tcgacgcgcg ggcccgcgag atcgcggccc
      541 tcgcggcgat cgtctcctcg gggatgtgcg gtacaccgct ggccgtccac acccgctcgg
      601 ctctcgccgc cggcgtcgcc ccggcggaga tcgtcgaagt ggtggtggag tgcgccgcgt
      661 tcgcgggctt cccacgagcg gtgagcgcgc tgccggccgt cgagaaggtc ttcgccgagg
      721 cgggtatcgc ctctccgccg cagcgctcgc ccagagaggt cgtcctggag gcgctggaca
      781 ccgcccggcg ccggacggcg accgacgggc gcgggccgga ggacgagccg ttcgccccgg
      841 cactgcgccc gggcagcgac acgacggtgt acacacttgc cccggaccgg gccctcgtcc
      901 tctgcgcgcc ggcgggccct gtggacggcg agggcgagat cctcgacatc cgcgtcgtcg
      961 acggccgtgt ggccgggacg accgtcctca cggagagcgc gtccgcggca ggtccggcgg
     1021 gcgcccggga aaccgccggg gcggcacgtc acgcactgac ggcgttcctg cgggacctcg
     1081 acgcggtggg ccacgggccg gccgccgagt tcgtgctcgg cgggcccgat ctgctcgacg
     1141 acacggcgcc tctcctcgga ccgctggcgg ccggcatccg cccacgggtg tacggactgg
     1201 gcgaggagtg cgccgcggcg gtcttcgagg acgccggccc gtccggcccg gtgatcgcgc
     1261 tcgccttctg cgaagggggc cgggtccgca gcctccgggt ggcgggggac gaccgtgccg
     1321 gcgcgggccc cggaccgggc ctgcgcgacg gctgacaccg aaccgggagg aaccgcacat
     1381 gccgctgtac gccttcgaag ggcgcttccc cgagatcgcg ccgaccgcgt tcgtccatcc
     1441 cgacagtgtg ctgaccggtg acgtcctggt cggcggccac tgctacctgg gaccgggagc
     1501 gagtctgcgg ggcgacttcg gccggatcgt cgtgggcgag ggggcgaaca tccaggacaa
     1561 ctgcgtgctg cactgcttcc ccggacgcga ggtgcgggtc ggtgcggacg gccatatcgg
     1621 ccacggctcg gtcctgcacg gctgccgcgt gggaccgggc gtcctggtcg gcatgaacgc
     1681 cgtcgtcatg gacgacgccg aactgggcgc gggcgccgtc atcggcgccg gctgcgtggt
     1741 cccggccggc atggccgtcc ccgaacggca cctcgtcgtc ggggtacccg ccaagatcct
     1801 gagggagctc accgcggacg aactggagtg gaaggcccgg ggcacggcca cctaccagga
     1861 actcgccgtc cgctgcgtga cggggctcag caccgtgcgc ccgaagtccg gtccaccgcc
     1921 cggcgacagc ccggcacacg tcgccggatg gcggcacgta cccctgcacg accaccgggc
     1981 gggcgcctcc gccacggagg ccaccggcac accggccccg cctgacggcc ccggccggga
     2041 cctcggctga accgccggac cccggcccct tccgccacca ccgcgccacc gcaccatgga
     2101 gctcaccgtg atccaccagc cttccccctc cggacaccac cgcagacaaa aagtcatcga
     2161 cgacgtggac acccgcctca tccggctcat cggcaagcgc cgggcggtct cggaggaggt
     2221 ccggaacgac cgtctcgccg aaggcgggac acgtaccgac accgggtggg agatgcacgt
     2281 catcagccgc taccacgagg cgttcggctc cccgggcagg gacatcgcgc tcggtctcct
     2341 gcggctctcg cagggcgagc cgccgacggg ccggccctcg gcaccggacg cgttcctcgg
     2401 ccccgccgac agctacagcg gcgtcgccca ccggcagttc gccggatccg gcggcccggt
     2461 actcctcatg gacagcgccg ccgacgtgct cgacgccgta gggcgggggc gggcgggctc
     2521 gggaaccgta ccggtgcaca acaccacggc gggccccgtc gtggaggtga tggacgccct
     2581 cgccctcggt gccccgctga gcgtcatcgg tgaacggcgc cttcccgtga ccctggtcct
     2641 ggccaccgtc aggccgggcc cgcccgacgg cgtacgcgtg gtgcgcaccc acccgcacgc
     2701 gtacgcgcag tgcgcgtcct ggttcgccgc ccacctgccg ggggcccggt gtgccgccgc
     2761 cccgtcgacc gccgcgggcg cggagacggt ggcccgggag ggggacgcgt cgcgtgccgc
     2821 cctgtgcgcc ccggcgaccg ccgagcgcct cgggctgcac ccggtgggcg ggaacctgac
     2881 cggaacgccc cccgcggtca cgcggttcct ccgggtcgtc cgcgtcgcgc caccgcgtcc
     2941 gcccaccggc cgggacctga ccactctcgt cgtacccgcc gaccgcgtgc ccctgctcac
     3001 cgtcgtccgc tcactggcgg catccggcgt ccacgtccag gacctgcacc ccggcgggcg
     3061 gcatcccgac gggtacctgt ggatcgacgt cgccgggcac cgggaccagg cgcccctggg
     3121 cgaggccctc gaacggctgc ggcgggagag cgaccgtgtg cgggtactcg gttcgtaccc
     3181 cgcggcatcc gcccgggccg tttcaggaga aaccctgtga agtcccctca cctttcggta
     3241 aaccgggtgt tccgggccca ccgcaccgtc tcgacggccg gggcgccctg agcacgccca
     3301 ggagacaggg gtttccttcc aggaggagag gccgtgcccc gcacacccaa cgagcgcctg
     3361 cgcaccctcg tgcggcgcag cggctggagc cattcccggc tggcccaggc cgtccggctg
     3421 gtggcagccg aacacgagag accggtgctg tgcgaccaca cctcggtgtc gcggtggatc
     3481 gccgggaccc agccccggcc ccccacgtcc accttcctcc tcgaagcgct gtcgcggaag
     3541 ctgggccgca ggatcacggc ccaggaggcg ggtctcaccc gcgcgcccgc ggccccgctc
     3601 gtcctgtcct ggcaggacga ctcgctgcac cgcctcgacc gtctcgtcga gttcgaactc
     3661 gacccggccc gggtccatct gctcgaagcc ggcacgtacc gccccagcgc cctgctcccg
     3721 cccgacccct ggagcccgct cggctccccg gcggcgaacc cggagccggt gaccggccgc
     3781 gtcggcggtg cggaggtggc ccagctccgc tccctgaccg agctgttcgc cctcagcatc
     3841 gcccagcacg gcgggcaggc gatccggccg gccctggccg cctacctggc gcacaccgtc
     3901 acgccctggc tgcgcgcccc ctcctccgac accacccgcc gtgagcttct cgccgccggg
     3961 gcacagctga cgctgctgct cgccgaggcc tgcatcgacg cggacggcca tgccgccacc
     4021 cagcactacc agcaactggc cgtacgcctc gccgccggct cgggcgacca cgccaccgtg
     4081 gccatcgccc tgcgggcgat ggccacgcac gccaccggcc tgggccaccg gggccccgcc
     4141 gtcctgcacc tcacccagcg ggccgtcgaa cacgcccgcc acgccccgcc ggccgtccgc
     4201 agctacacgt acgcgcacct cgcggtcgtc caggcccatc acgaccgccg cgccgccctg
     4261 gacgcgctcg cccgggccga acggttccac accgaagggg ccgacgcccc tcccggccct
     4321 ttcacgagct acccggaggg cgccctgcac taccagcgcg cgcagacgct cgacgcgctg
     4381 aagaacacac caggcgcctt actcgccctg aacgcctcgc tccgcgcgcg taccccgggc
     4441 gagcaccgcg cggcgctgct cacccacgca cgcctcgccg ggatcctcct ccgccacggc
     4501 cacctcgaac gggccctggc acactggcag gtcttcgtcg acgagtaccc caccctccgg
     4561 tccccccgca cgcaccgcat gctgaaggcc atgcacgggc agctgcgccc gcacggccgc
     4621 caccccggcg cacgggacct cctcgcccgc gccgacgtgc tcctgcgctg agacggacac
     4681 cggcggaacg gaacgggagg ggccgcgtcc cgccccggac cggaccgccg ggtcaggagg
     4741 agggaaggcc gtcgtgtaat cgaatggatc ctgcatggtc aacaccctgc ggagtcgggg
     4801 ttccgggaca cggcgacacc acggccggtg cgtacggatc cctccatcag gcccaaggcg
     4861 gcgtccgggt ctccgtgccg gcggggcctg ccgggcacac ccgcgaggac gggccggtcc
     4921 ggttcagccc ccggccagtg gggaggccgg cttggggaaa cccccgagcc cgatctcggg
     4981 gacggtgatc cctccgtcga cgaagagcgc gtgcccgctc acgtaggagg ccgccggtga
     5041 cgcgaggaag agcgtggcac cggcgatctc gtccgtggtg gcccaccgtc ccagcgggac
     5101 gtggctggtg agccagtcgg acaacgcgcc gtacccggtg gcgaaggcgg tcatgtccgt
     5161 gcgggtccag ccggggcaga cggcgttgac gcggacgccc tggcgtgccc agcccacggc
     5221 gaggctgcgg acgagtgaga gctgcgcggc cttggccgct ccgtacgcct ccagcgccgg
     5281 cagggacgcc accccggcga tggacgacat gaggatcagg ctcccccggc cggaggagac
     5341 caggtggtcg tgggcggcgc cggcgagtgc cgcggtggcg ctgaggttga ccgcgatgac
     5401 gctgttccag tcctccgggt ccgcgcggtg caacggctcc agcagcaccg cgccgtcctc
     5461 gccgtggggc aggacaccgg cgttcaggac gacgacgtcg agcccgccca gcccggccgc
     5521 ggcccgctcc accagaccgg tggccacctc gggaagcgcg aggtcgccgt cgagggcgac
     5581 ggctttcctc ccgcgctcct cgacggccgc cacggtggac cggagggcgg ggagggtacg
     5641 ggccgcgacg gcgacgtcgc agcccgcctc cgccagtgcc tcggcgaccg ccttcccgat
     5701 gccccgggag gcgccggtga ccagagcccg gcccccgtcc agacggaaac ggtccagcac
     5761 actcatcggt gttcctttcc ggcggccggg agccgcaccg gcagaacccg gccgtcccgt
     5821 acgaggtgcc ccgccgcgga ccgggcggta cacgagcgac gcgacttgtc ctgacgccca
     5881 ctgaaccaag ccgggcggca tccggcgggt ggggcggggt cacgactccg gtgcaccggg
     5941 ggcgactttg cgcgttcgtg aacttcccgg cccgggagcc gccaccagga cgtccccggt
     6001 ccggagggcg gaccgcgccg ctgccccggg gcacgcccgc gcggctcctg ccgcagttca
     6061 ccccctcgcg tccggcagat gggtacggtc ggaccgtccc cgtcctccac ccccgaccga
     6121 ggagctccca tggaagacga gcaggaccac ccccttctcg tccgggcccg ccgtctctcg
     6181 gaagtcctgc tggcccccgc cgcccagcgc gtcgaccaag acggcctccc cgccgcccat
     6241 ctggacgagc tgcgcgcctc cggactgctg ggggcgagcg ctccgcaggc gtacgggggg
     6301 gccggagtcc ccgacgcggt cgcccgggac atccaggagg ccctggccac cggctgctgc
     6361 acgacctggt tcgtgcaggc ccagcaccag tccccgctgc ggctgctcgc cgcgtcggac
     6421 agcccggcga aggagcggct gcttccggag ctggcgagcg gcagggtgat ggcgggcgtc
     6481 gcgtacgccc atgtccgctc gtttccccgg gttccggtgc gggccacagc cgaccgcggt
     6541 ggctggcggt tcgacggcac cgtcccctgg tacaccggct ggaagctgaa cgacgtgatg
     6601 ctgctggccg ggatcgacgc cgacgacgag gtggtcttcg cgttcaccga ggccggggga
     6661 cagcccgggc tgcgcgcgtc ggagcccctg cggctggtcg ccgtttcctc ctcccgcacg
     6721 gtctccctgc ggctggacgg cctgtgggtg ccgccggagt ccgtcgtcct gcgggtgccg
     6781 agggagcgtt gggccgttac ggacctggcg cacgcctccc acgtctcgcc cgccgtgttc
     6841 ggcgtcgccg aggccgctct gcggttgctg gaggagaccg gtgcggaggc cgccgcgacc
     6901 gcgcgcggtc tgcgggccga actggccctg gtccggcggc acgcctatgc cctggccgac
     6961 cggccggaac cggaccacgg tgttcccgag cgcaccgctc tgcggctgcg cgctctcgac
     7021 ctgctgcgca cggtgaccac cgcggtggtc gtcgcgggag gcggccgtac gaccggcctg
     7081 gaccatccgg cacaacgact ggccagagag agcctgttcc tgctcgtcca gggacagacg
     7141 gcgccggtcc gccgggcgca cctggcgtcc ctggccccgg ggccgggcgc cgccgccccg
     7201 ccctgagtcc ccgtcgtccc gagtccccgc cgtcccgagt cttcccgtcc gagtgcacgg
     7261 aggtgcgtca cgatgcagga gcggttccag agcgtccgga ggcaggagcc cggcggcaca
     7321 ccaggccttc cggaaccggg tgtcgaggtg tccgccgctc aggccggagt ggggcacccg
     7381 ggcgacgtcc ttctcgtcca cgacgccgta ctgccgaacg ggctctcctt ccgcgtccgg
     7441 gtccccggcg cacacgacct gttcggcgac cggggcagcg gtggtctccc ggacgacgcc
     7501 ttcctgctcc ggtctgtggt ggagcagtgc gcgtacgcga cccttcagca cacggggctg
     7561 ctgcggcccg gggaggtccc actgaacacg tcgtcgagca gccgtgtcct gaccgccccg
     7621 ccgctgcggc gcttccaggg ggagctgctg gcgacatgcc tcgtcgaaca gctccggacc
     7681 agccggacgg gacgcacccg acgtgtggcc gcttcgtgcg tcctgcggtc gccggacggc
     7741 cgggtggtgg cggacggcga gaccggcgcc ggggtcctcg aacgcgccct gtaccgggcc
     7801 tggcggggcg ccggggtggt ccgggcggga aacctgccgc ctgttcagga cggggcccgt
     7861 gcccgtaccg gaagggtcag gtccctgccc gggaaccagg tcctggcccg ggccgggcgc
     7921 gaggacggag gcgacgcgca cgcggtgctg cgcctgtccg gccctcatcc ctacctgctg
     7981 cccgcgtccg cggaccatgt gacggggagg ctgttcgcgg aggcggcccg gcagctcgtg
     8041 ctcggtgtgt gcgggccgta caccgggctg cgcgcgctgc atctgtcgtt cctccggctg
     8101 tgcaccctgg aggagtccgt gcgggtgcgc gctgttccgt gctccgggcc gcgggcgtcc
     8161 gaccggtggc gtgtcctttt ctcccaggcg ggcgccacgg tgtgcgccgg acacgtcgag
     8221 gcggacgtcc cggaggggcg ggagcggcgg acacggcacc gggacgggtg acccggggcg
     8281 ggtggcccgg gacggacggt ccgggacggc cgcgccctgt gggtgcccga agacaggggc
     8341 cgccgtacct gcggacgcgc cgtggacacc gtccgcttct cactcccgcc tcccgcgcgg
     8401 agggccgccg gccgtgcttc gccgtccccg tttcccttcc gtccggccgg gcatcacagg
     8461 aacgaggcag ccgtgaaccg gccggagcgc cggtcaccac gacggaaccg ttgtcgctcg
     8521 tcccgcggcc gcgcccggcc ggggaccgag cagacccgac cgaggagtgc catggcgcac
     8581 gaacctgttt cccgatgccc ggtgctggac gtctcggggc gctccctcca cgcggacgcg
     8641 gcggcgttgc ggtccgaggc gcccgccgtg cgggtcctgc tgcccggtgg cgtcacggcg
     8701 tgggcggtga cccggtacga cgtcatcagg gcgctgacct ccgacccccg cgtctcccgc
     8761 gacttcgcgc ggcactggcc cgggcggagc gaggtgcccg acggctggcc gctggccgcg
     8821 gtcaccttcc agcagaactt cctgaacacc tacggagccg aacaccgcat gctgcgcggt
     8881 ctggtcgcgc cctcgttctc cccccgacgc gtctcggcca tgcgtccggg catcgaagcg
     8941 gtggcggaac ggctcacgaa cgcgtgggcg gcgctcggtc caggagaagc gaccgatcta
     9001 cgcgccacct acgcactgcc gctcaccatg acggtgatct gcgagctgtt cggggtgccc
     9061 gagcacctgc gggggcccct gggcgcggcc atcgaccggg ccgccgacac cgcggcctcg
     9121 cccgaacagg cccttgccgt tcacgcggag atcgacgcgc gcctggacga actggtctcc
     9181 cacaagcggg cgcaccccgg agccgacctc accagcgacc tcctcatgaa tcccgcggag
     9241 gacggctccg tcttcaccga ggagaccctc aaagggaccc ttttcctgat gataggcgcg
     9301 ggatacgaga cgacggtcca cctcatcacc agcgcggcgc acgccctgct gaccggaccg
     9361 gacgtcgtca cgcggatccg gaagggtgaa ctgcgctggg cggacgtggt ggaggagacc
     9421 ctgcggctcc aggggcccat catgtacctg ccgttgaggt atgccgtcga ggacatcgac
     9481 ctgggcgagg gggtgctcgt cagacagggc gacgcgatcg ccgtggcctt cgcggccgcc
     9541 ggacgggacc cggatcggca cccgaagggc cccgacgact tcgatccctc acgcgcggac
     9601 aagacgcatc tcgcgttcgg gcacggaccg cacttctgcc tgggcgccca tctcgcgcgc
     9661 ctggaggccg aggtggcact gcgcacgctc ttcacccggc tgccgcgcct ggccctcgcc
     9721 tcaccggagc ggacgccgga ccggcttccc tcgttcatcc tcaacgggct gaccgggctg
     9781 ccggtcgttc cggtaccggc ggcctgaccg ccgctcccac cgggcgggga cgggtggttg
     9841 ccggggcggc ccgtcacgtc gtgtccttca tcctctcgga tggctctgta ccggttcgct
     9901 gtgacaggcg gcgccgggca ggtaggaagg aacggaccgt cccacccgtc caggacttcg
     9961 cgtcgggcgg gaacgcaccg ccgtgcttcg aggaggctcc gtgcggaacc agacagcacc
    10021 ggacatgccc gccccgcccg tacgagcgcc gaagggcggg gtgcccctcc acctcgcggc
    10081 gctgtccgac ggtggcgccg acccggacgc ggcccacgac gacgcgggca tggagtggtg
    10141 gtacgtcaat ctgcacctcg tcaccggcgc aggtgaaccc ctctccgtct tcgcggcttt
    10201 cttccgcatc ggagagaggg atgacgaggg aggagtctcg tactcgcaca ctctggcggc
    10261 ggcctggagc gagccgcgga cgcgccgcta caccccgctc agctgcgtcg acgacgcgaa
    10321 cctcaccctg atccggaagg tgctgcacca cgaccgggcc tacgcgcccc ggctgcggga
    10381 ggccctgagg cacctggtct cagcagaccg ccctccgctg ccggatctgc cgctggaggg
    10441 cgaaccggcc gtgcgtgccg tcccgttcgc ggtcgactac ggcccccagg gcagcctcgg
    10501 ccgcgatccc cgcggccgct accgtctgcg cctgcgccat ccggggcggc ccttcgcgct
    10561 ggactgccgg ctcacccccg tgcgtccagc ggcgtggcag ggcggggacg gcaccgtggc
    10621 cggactgggc gagagcggtg agggcatgcg gtactacagc gtcacccgtc tggaggcgga
    10681 gggcacggtc accgtggacg gcgccgcgca caccatcgcc tcgggcagcg cctggtacga
    10741 ccacgagtgg ggtctcgacc cgatcagccc cgagcgggga tacacgcacg acgaacccga
    10801 gtgggactgg tgcggtctcc acctcgacga cggtcaggac ctctccgtct cctcctggcg
    10861 caggtccgac cggcgttcgg ccaccgggcg gacggtcgat cgcacctcgc tcctggtgtc
    10921 accggacggt gccgccggca cgctcgacga ctggcggttc gagcccctgg aacgctggac
    10981 ctcgctcgcc acctgcaaca cgtacccggt cgcctggcgg ctgacagcgc cctcgcacgg
    11041 tgtcgacctc gaactgacag cggccttcgc cgagcaggag gtacggacga tcacggtcca
    11101 ccggggtttc tgggagggac gcgtcgaggt gtccggccgt gccgggggcc gtccggtcac
    11161 ggggcggggc ttcgtcgagg tcaagcccgc ccaggtgctg ccccgcatcg atcccctgat
    11221 ggacaccatc ggcgcggaga cccgggccca ggtcgccctc ctctatccgg ccgcggcgag
    11281 cccgtccacg acggagtcgc tcctcggacc gatcgccccg gacctgctgg cggtcctgcc
    11341 ccacgagagc ctgcaccgcg cgctgatggc accggtgggt cacaccgtcg gcggcatcgg
    11401 gaagagctgg cggtccttcg ccctggtcgc ggtactggaa gcactgggtg tcagcagcga
    11461 cccgtaccgc cctctgctcg cggcggtgga actcctgcac accggcagtc tcatggtcga
    11521 cgacgtgcag gacgccgcag tgctgcgccg gggcaggcct gccgcgcaca ccgtgtacgg
    11581 agaggcgacg gcgctcaacg cgggaacggc cgcctacttc gtcttcgacc gggtcctgcg
    11641 cgccctggtg ctgtccgacg ccgaccggct gcggacctac gagatcctgt gcgcgatgct
    11701 gcggtgcgcg cacgcgggcc aagggctcga cctcacccgc gactgggcgg acggtccggg
    11761 gccggacccg gccctcctgg gagagcgcgt cctggccgtg caccggctga agacggcgct
    11821 gccggtgcga gcgctggcgg agatcggcgc ggcgctcggg aaggccggcc cggcccagga
    11881 ggcggcgctc tgcgactact tcgaggcgct cggcctcgga taccagatcg ccgacgacgt
    11941 gtgggacctg aagggacacc gggccgccgc cggcgagttg aggaaggaac cgggcgagga
    12001 catccgcaac ggcagggtga cataccccct ggtgtgcgcg ttggagctgc tgcccggccc
    12061 cgacgcccgg tggctgtggg agcgggtgcg cggacggccg caggaccggg cggagatcca
    12121 cgcctgcgtc cgcgccatca ctggatgcgg ggccctggaa ctcgcgttgt cgcgggccga
    12181 ggagaggctg gaccgcgcat gggaagtgct ggagcccttg ctgcccccgt atccggtcgt
    12241 cgccctgctg aggtcgctcg gtttctacgc ggtcacacgg gacgccgagc tgaacggctg
    12301 aggcgggcag atgaattcgc ccgatccgca ccactcgggt gccctgcgcg tgaggactgg
    12361 aggaggggcg agcccagagg tccgagcccc gggggacggg gcgggccggg ttccgggacg
    12421 cgcgtcccgc cggactcgaa cggccggggc gtcgcaggcg ggccggccgt gacaccgagg
    12481 gccgagcgtc tcgtgcgccc cccggggagc agccggccct cgtggcccct gccgcgcccc
    12541 gacagcggcg atgtcccgca gtccggcttc ggcgccgcgt atcgctcgtc cggggccgtg
    12601 taccgctcgc cgcaggcgag cattaaggtg taatccgaag gatgtacgca tctgcccgaa
    12661 tgccggagca gcaggctcag gacccgtaca gcgcactgga aggaaacgaa gccgtgcatg
    12721 gcgagtacaa ggtgcccggc ggcaagctgg tcgtcgtgga tctggatgtc gaggacggtg
    12781 tcctgcgcga tgtgcgggtc gccggggact tcttcctgga gccggacgaa gcgatcctct
    12841 cgatcaacgc agcccttgag ggttcacccg cgtcgacgga caccgcgggg ctggccgccc
    12901 ggatcacggc ggcgctgccg gagtcgaccg tgatgctcgg gctgacagcg gagggggtcg
    12961 gcatcgccgt ccggcgcgct ctggcccgcg cgaccgagtg gagcgactac gactggcagc
    13021 tggtgcacat ggagccgcag gctccggccc tgcacatggc gctggacgag gtgatcaccg
    13081 ccgaggtggc cgccgggcgg cgagccccga ccctgcgggt atgggagtgg gcctcgccct
    13141 ccgtggtgat cggcagcttc cagtccctgc ggaacgaggt ggaccccgaa ggggccgcga
    13201 agcacgggat gaccgtggtc cgccgtattt ccggtggcgg ggccatgttc gtggagccca
    13261 tgagtacgat cacgtactcc ctgtccgtgc cggagtcact ggtcacgggt ctctccttcg
    13321 cggacagcta cgcctacctc gacgactggg ttctcggcgc actcggcgac atggggatca
    13381 aggcctggta ccagcccctg aacgacatcg ccaccgaggc cggcaagatc gccggtgcgg
    13441 cccagaagcg cgtggtcggt ccggacggcg gccctggagc cgtcctccat catgtgacga
    13501 tgtcctacga catcgacgcc gacaagatgc tcgaagtgct ccgcatcggc aaggagaagc
    13561 tgtccgacaa ggggaccaag agcgccaaga agcgggtcga cccgctccgc cggcagacgg
    13621 gtctcgcccg ggagcaggtc atcgagaaca tgatcgcctc cttccgcaac cgctacgggc
    13681 tgaccaccgg cgcggtcacg ccggaagaga tggcccgcgc ggaggagctg gtgcggacga
    13741 agttcgcgac cgaggagtgg accgcccgcg tgccgtgacg ggcagcgggc accggccggg
    13801 gcccgggttc accccgcccg ttcgacgctc cacagcggca ggtgctcgaa gaaggagacc
    13861 gcctcctcgc gccagcgggg ccgccagccg gccgccaccc gcgaggcttg ttccgcgtga
    13921 cgccgcatct cgtcccgcag tccggccgcc actccccgtt cctcggcgat gtcccgcagc
    13981 gcggcgagtg tctccggggt gccggacggg tcgccgagcg cggcctccac cacggcccgc
    14041 tcggtgccgc tcaccgcgga cagcagggcg acgacggtgt aactgcgcct gccgtcccgg
    14101 atgtcggtgc cggtgggctt gcccatcgcg gcggggtcgc cgaacaggtc gaggtagtcg
    14161 tcgcgcatct gtccgcagat cccgaccagt cgcgcgtagc gccgcagttc gtcctcgtac
    14221 gcggccggcc gctcccccgc cgccagcagc cccagccaca ggggggccag gagggagtac
    14281 cgggccgact tgtagtcggc cacacggtgc aggaggtcct cgtccgggga gggggcgaag
    14341 tcgcgttcca ggtcgatgat ctggcccatg aacgtgtcgg ccgccgcccg ggtctgcacc
    14401 tcggccatct cctgccgtac cgcggcgggc aggtccgcgt cgtgcagcac ccgcagggac
    14461 agggcgaacg cgaggtcgcc cgcgaggacg gtgagtccga gggcggcccc cgggtggtcc
    14521 gggaactgcg cgcggtaggc gtagtacgtg gagggtccgc cccggcgcgt ggggctgtcg
    14581 tcgatgaggt cgtcgtgcac caggccgtgg gtctgcagca gttcgacact gagcgcggcg
    14641 gcgtccagtc cggccacggg gcggtccgtc accaggcggg ccgcctcgtg gagcagggcc
    14701 acccgcatcc gtttgccccc gcgcagggac aactcccgca gcagccgcag gcagtccggt
    14761 gtgaacctgc tggacgccgg cgtgtcgagg gtggtgccca gcctgtcgaa gtactcctcg
    14821 aacagggcgt tgaaccgccg ctcgtatccg gcgactcgtt ccagtgccgc catctgctgg
    14881 gtcatgcggg gttcctccgg ttccggaacg gacacacgcg gttccggacc ggacacgcgt
    14941 gcgcaccggc gtgcggggtg gacgcacgcc ggtgccggtc ggtgacctta ccgccagtgg
    15001 cgccgggccc ggtccgggcc gtcgcaccgc ccggtgccac cggggcgccg gaccgccggt
    15061 tcccaccccc gctccgtccg tccggtgtcg acggggaagg ccgggtgtct tggggtcaga
    15121 tgtcgccccg ggccatggcc agcagccggt cgaggacggc tccgtcggcg cgtacgccgt
    15181 cgtgggcgtg gtcccgggac acccaggtgc gcagcccgcg gacggcgtcg gcggtggcga
    15241 gggagtgctc ccggtcgacg tacatgtcgt cgtggtagac cgcggcgacc acggggacct
    15301 cgttggcggc cagccggtcc aggtcgtaga gggcgggcca gtcggtgcgg gcggccagga
    15361 tcccggcggc cccacgcagc gggacgagcg ccggatcctc ctcgaactgc caggggtaga
    15421 ccatctcccc ggtgaagcgc aggggtgtgc ccggtgccgc gtcgaaggcg gggaactcct
    15481 cccggatccg gtgggcggac cagtcggtgg cgcgggcgcc ctgggcgtag atgggttcgt
    15541 ggagcgccgc gtagaggggg cgttcggcga aggagaccgt ggcctccacg ccccgcagga
    15601 aggtgtcggt gagttccggg ccggccgctc cgtcggtgaa ggcggtctcc agcaggtagt
    15661 ggagcgagtc gaacttcgcc gaggtgccga aggtgatgcc gagcgtctgg aaccgccgca
    15721 ccgtgagccg ctccccggtg ggcatgcgca cgtcgtgggc gtccaggtgg gcggcgacgg
    15781 cggcggcgag cgcctggtcc cccgggtagc gcgcgaagta gcgctcgttg tgggcgaggg
    15841 tacgggcgta ggcggcgcgg tacacgtcgt cggcgtggcc ggtcagggtc ggcagaccac
    15901 cggtgatgta cgcctggctg agcccttcgg gggcgaggct gaggtaggtg agggtggcga
    15961 aaccgccgaa gctctgcccg aggacgctcc agggccggtc cccctggagg tggcggcgca
    16021 gcagttcggc gtcccggacg atggagtcgg cgcggaagtg gccgaggtgg ccggccgccg
    16081 ccgcgtggtc ggagccgaag cgggcgaggg tgcgccggtc cacgggcgcc gaacgcccgg
    16141 tgccgcgctg gtccatgagg acgacccggt ggccttcgag tgcgcgccgg agccaggccc
    16201 ccgccgcgtt cgggcgttcc gcgcggccgc cggggccgcc ctggagccag agcagccggg
    16261 gcaggtcctc gtgctcgcgg ccttcggcga cgacctcgcg ggcgaagagg ccgagggtcc
    16321 cggaaccggg tgtgcggtgg tcgaggggca cgtcgagggt gtggtcggtg cagaccaggc
    16381 cgccgtggcg gtaggagacg agcgggggtg tggacatggc gctccttgtc gcgtcacggg
    16441 gtgcccgtca ccgcgcgggg acggggggcc ggggggccgg ggggccggga cgaacagtcg
    16501 gggaaggacc ggggcgaacg gtcggggaaa gggcggaaca aacggtcggg gaaggaccgg
    16561 ggcgaacgga tcggggaagg accggggcga acggcgcggg cgggccggcg gtccggcctg
    16621 cccgcgcccg gccgctcagt agccggcgac gcccagttcc cggcagatct cgacgagttc
    16681 ggggtggacg tagcgcccgt tctcctcgat cgcgacgccg tccaggtaga tggacgggcc
    16741 gagcacgctg ccgtcggtgt gggccgcggc gacccacggt tcgccgccga tccacgcgcc
    16801 cttcgtgccg atgccgagtt cgacgcatcc gaagacccgc tcgtcctcga cgatgcggcc
    16861 ggtcggggcg agtacgcccg ggttgaagcc cagcgaccag tgggcgatcc ggaacatgtt
    16921 cgggtcgtcg aaggactcca tccagcggcg gaaggtgtcg gcgtcggcgc cgccctcgat
    16981 cttggtgacg acgcccttct cgacggtgca gcggaccggg gagcgcagca ggccgatctc
    17041 gtccggcggc cacagggctc cgtcgaagac gaggacgccg tcctgggtct cctccagggg
    17101 gttccaggag atctggccgg acagcatgac cgtttcgccg ggcttctccg cgggcttgcc
    17161 gcgcaggttg atcggccggt cgccgttgcg gccgacgagg tcggtgccgt tggcggaggt
    17221 gatgcgtacc tcgtcggcgg cctccaggag cgcgacgagg gccttgccga ggcggatgac
    17281 gccctggaag tcggggcgtc cgacggtggc gaccagcatc tggacgtcca tggcggtgag
    17341 gttggtgtag cggcagccgt tggccatggc ggcgcggaag gcgtcggagt gcatgacgta
    17401 ggagacggcg aactcgatcc acacgtcggc gtcggctatc gcgccggcca cggggcgggg
    17461 cggctccatc gaggcgccgg gcatcgtctc gtaccagacg atgacggggt gggcgccggc
    17521 cgcggcgacg gcctgtgcgg tggcctccac cacccggcgg tcgctgctgg tgtcaccggt
    17581 gaggacgacg tgctccccgc gcttgacgag catgacctcc tcgaccagct tgcgtgcggc
    17641 cagggccagt tcgaagctga ggtactccgg acgcggttcg agcctgctgt acatgtccac
    17701 ggtgggggtt ctccttgcct tgcgggtggt gcgggtggtg cggggatggt ctgtggggcg
    17761 ggctcaggtc ttgaggatct gggcggagtc gccgagcgag ctgcccgcga tcactccggc
    17821 gccgatgagg ttgagttcct cgtcggcggc ggggccgcgc agcttgcggt agccgatgcg
    17881 gacggcgagc gcgccgagca ccagccagca ggcctggggg gtgaggatga ggaggccggt
    17941 ggccagcatc acgcccatct gccggcgggt gccgccgatc agctggatcg cggcgccggg
    18001 aacggcccag agcagcatgg tgcgtacggc gtcggggtcg ctgaggccgc tcttgatggt
    18061 gtcggcgtac accttggcga cgggcgggat gagtccctgg ccgaagtagg agcgccaggc
    18121 gacggccacg acggccaggg cgacgccgaa gccgatcagg gcggccagga actgctggcg
    18181 gcggccttcg cgctcgtagg ggtcccaggg gcggtggtcg cgtcgcagca gccagcccgc
    18241 cttgaggtcg tagcccatgt cggcgaaggc ggggccggtg gcggagacgt atccgatcag
    18301 cagggccagc ggcaccgagg ggatgcccat ggcgaggccg aggacgagga agatcagggt
    18361 gaccgcgaac gacgggaacc agccggactg catggccgcg aggccgacga tcagctcgtg
    18421 gaccagggcg gcgaaggccg cgaagaggac ccagccgacg atgccgagcg ggctcatgtc
    18481 gccgatcaga ccgccgagga ccgcgaggag gacggcgccg gcggtgaaca gcgcgtagcc
    18541 gcggatcagg gcgagccgca gcccccgctc gtcgacggtg tacgcggtgg tcgggtcggg
    18601 ctcgggcacg gcgagggtgc tcgccggctc ccggggaggc ttgttgcgtg tgcgtgcgcg
    18661 acggcccatc agcatgtgga cggcctgtcc gagggcgacg atgcccgcgc cgaccatcac
    18721 gccgtgcggg atgaacccgg agccgagatc ggtgccgaag aggtccgggc tgtactggcg
    18781 cagcatcagg ccgacgccga acatcatcag tgcccagacg ttgccgagga aggcgacccc
    18841 cgcggcggag agcggcaggc tgaagagggt tccggccaga ccgacggcgg ttccgccggc
    18901 gaggacgagg gcgcggcgcc ctcccttgtc accggccttg atggtctcgg ccgcggcggt
    18961 tccgggcggc caggcggcgt cggcgggcag cagccgggag ccgaaggcgc ggtagagcac
    19021 ccaggcgtcc acaagcaggc cggcgaacga tccggcgagc atcggccaga ccaggtcctg
    19081 gcgcccgaag acgtagggga tggccacgga ggtcagcagg gcgttcgccg atgcgaaggt
    19141 ggccgccgag atcgcgctct gggcgaggtt ctgccggtgc acggaccgca tccggcgcag
    19201 gaagccgagc gggatgcggc cgatcagcat cgcgacgagc gcgccgacga ccgaggtgtt
    19261 ggcggagatg cccagcttgg agaccaggtc gataccgatg acggcgccga cggcggcgag
    19321 caccaccagg atgaccagca gcacgggttc gaacacgcgc gggtgggagc ccgtgtcgtc
    19381 gggacgggag ccggacggtg gtggttcgcg gtgcggggcg gaggcttggt gcgccacggg
    19441 gcaccccctt cggtgagcag gactggggag acgctgtccc ccggtcggcg cgcgcgggca
    19501 tggcggggcg caccggcggc gccgtgcgcc gcgggatcga gcggtatgcg gttggggccg
    19561 gttcagccgc cgagtgccgc ggtgacctcc gcggctccgg cgcgtaccag cggtacgagt
    19621 gtgccgacgg cccggtccac ccggtgggag gggccgatga cggtgaggga ggcggcgacg
    19681 gcgcctccct ggaggaccgg ggcggagacc gcggtgacgg cctcgtcgta ttccccgtag
    19741 ctgacgcagt gcccgtcggc acggacccgg gcgtagcagg tgaacagggc gtccaggtcg
    19801 gtgatggtgc ggtcgttgaa ccgggcgagg ccggtggggc cgaacatctg gcggatctcg
    19861 cgttcggggt ggtgcgcgaa gatcgcgtgc ccggaggctc cggcgtgtcc gggcatgacc
    19921 gcgccgatga tcgcggtgta gcggaccggc ccggtaccgt cgaccgcggc cgcgcagcgg
    19981 tagccggcac cgtgcgggac gttcaggacg acgctctcgc ccgtctcgcg cagcatccgt
    20041 gcgagtacgg gccgggccag cgaggggagc accccgctgt actcgctcac ccgggcgagc
    20101 cgggagagcg ccgggcccgg gcggtagcgg cgggtggtgg agtcacagag caggaaaccg
    20161 cgggcggcca gggtggtgag caggcgctgg acgacagcct tgtcccagcc gtgatggcgt
    20221 gagagttcgc tgacgcccca ctcggggcgc tgctcggtga aggtgagcag gaccaccagg
    20281 gcacggtcca cggtctgcag gacgccgggc gcctggggtg gggagccggc ctgaggggtg
    20341 tcgccgccgt ggtccgccat gggcccgcct ccttcgttct gtgcatgtcg tacgcccacc
    20401 ggcgggtctc ggaaccggcc cgatcggtgc ggaaaacgca acgccgttgc tttttctggc
    20461 gaaagaatgc gggtgtattg accaggtgtc aagagttctc aggcaattca tccacggtcc
    20521 gccgggatct ccccaaagga cggggaacgg cacgggcggc gtacccggac gggtgcggca
    20581 cggagggcgg tggccgcggg cggtgatgcg ggcgcagggc gtacgggagc aggacctgta
    20641 cggggggggt aggcggcgcg ggcccgtacg ggaggcagga gggcggcgcg ggcccgtacg
    20701 ggaggcacag gaggcggcgc ggggagccct ctgtacggga gtcaaggagg cggggaggcg
    20761 tacccggagc gggaagcggg ggcgagatgg gcctcggcgg ggttcctccc ggacgggccc
    20821 cgcgcacgca cggccgcccc ggcgggcgca gggcctgccg gggcggtcgg gtggtgcggg
    20881 gtcgcgcccg tgccgggcgc ggggcgggtc agcccagcga ggcgatggcc tcgttgaacg
    20941 tggccgacgg gcgcatgacg gccgcggcct tggccgggtc gggctggtag tagccgccga
    21001 tgtcggccgg cttgccctgg acggcgatca gctcgtcgac gatggtctgc tcctgctcgc
    21061 ccagcgtctt ggcgagcggc ccgaacgcct ccgccagctt ggcgtcgtcg gtctgcttcg
    21121 ccagctcctg ggcccagtac agggccaggt agaagtggct gccgcggttg tcgatgccgc
    21181 cgaggcgacg gctgggcgac ttgtcctcgt tgaggaacgt ggcggtcgca cggtccaggg
    21241 tgtccgcgag gacctgggcg cgggcgttgc cggtggtctg cgcgaggtgc tcgaagctga
    21301 ccgcgagggc gaggaactcg cccaggctgt cccagcgcag gtagtcctcc ttgacgagct
    21361 gctggacgtg cttcggcgcg gaaccgccgg cgcccgtctc gaacaggccg ccgccgttca
    21421 tcagggggac gacggacagc atcttggcgc tggtgcccag ctccaggatc gggaagaggt
    21481 ccgtgaggta gtcacggagg acgttgccgg tgacggagat ggtgtcctcg ccgcggcgga
    21541 tgcgctccag cgagaaggcg gtggcctcct gcggggtcat gatctcgatc tgcaggccgt
    21601 cggtgtcgtg gtcggccagg taggtcctga ccttggcgat gagctgcgcg tcgtgggcgc
    21661 ggtcctcgtc gagccagaag acggccgggc tgccggtggc gcgggcacgg gtgacggcca
    21721 gcttgaccca gtcctggatc gggaggtcct tggtctggca catccggaag atgtcaccgg
    21781 caccgacggc ctgctccagc accgcgttgc cggcggcgtc gacgacgcgg accgtgcccg
    21841 tggccgggat ctcgaaggtc ttgtcgtggc tgccgtactc ctcggccttc tgcgccatga
    21901 ggccgacgtt gggcaccgag cccatcgtgg acgggtcgaa ggcgccgttg gcgcggcagt
    21961 cgtcgatgac gacctggtag acaccggcgt agctgctgtc cggcaggacg gcgatggtgt
    22021 cggcctcctg gccgtccggg ccccacatgt ggccggaggt gcggatcatg gccggcatcg
    22081 acgcgtcgac gatgacgtcg ctggggacgt gcaggttggt gatgcccttg tcggagtcga
    22141 ccatcgccag ggccgggccc tcggcgagct cggcgtcgaa ggacgccttg atcttcgcgc
    22201 cgtcgggcag cgcctccagg cccttgagga tgccgccgag cccgtcgttc ggggtcagac
    22261 cggcggcggc gagcgtctca ccgtactcgg cgaaggtctt cgggaagaac gcgcgcacca
    22321 cgtgaccgaa gatgatcggg tcggagacct tcatcatcgt ggccttgagg tgcacggaga
    22381 acagcacgtc ctccgccttg gcacgggcga tctgcgcggt gatgaactcg cgcagcgcgg
    22441 cgacccgcat cacggaggcg tcgacgacct cgcccgcgag gacgggtacg gactcccgca
    22501 ggacggtggt ggtgccgtcg tcaccggcca gctcgatgcg caggctgccg ggctcggcga
    22561 tgacggcgga cttctcggtg gaccggaagt cgtcgacgcc catggtggcg acgttcgtct
    22621 tggagtcggc ggtccaggcg cccatgcggt gcgggtgcgt cttggcgtag ttcttgaccg
    22681 acgcgggggc gcggcggtcg gagttgccct cgcgcaggac cgggttgacg gcgctgccct
    22741 tgaccttgtc gtagcgggcg cggacgtcct tgtcctcgtc gttcttcggg tcgtccgggt
    22801 agtccggcag cgcgtagccc tgcgcctgga gctccgcgat cgcggccttc agctgcggaa
    22861 tggaagccga gatgttcggc agcttgatga tgttggcgcc gggagccttg gccagctcgc
    22921 cgagctcggc gagtgcgtca tcgatacgct ggtcggcctt cagacgctcc gggaaactgg
    22981 cgatgatccg tccggccagc gagatgtcac ggctctccac cgagacaccc gcggtcgagg
    23041 cgtatgcctc gacgacaggc aggaacgagt acgtcgccag ggcaggggcc tcgtcggtgt
    23101 gcgtatagat gatggtcgag tcagtcaccg ggtgctccgc tccacgtctg caacattgct
    23161 tgacatcaag atatctcgtg agcgcccccc tctccacagc ggcccgcccc cgtctcaccg
    23221 gacgcgctca ctccgctccg ggcggccctc cctctccggc cgtggccggt gtcccggtgg
    23281 cgggcggcct gcgctcgtac cagcggcggt cggcctccag ctgggcggcg agggagatga
    23341 gccgggcttc gctgcgggag ggccccagca gctgggcgcc cagcggcagg ccgtcctggg
    23401 tgaagccggc ggggacgttg actccgggcc agcccagtac gttccagggc caggcgtacg
    23461 ggcaggcggc ggtgatggcg aggtcggtgc gccaggcgct cagaccgtcg aaggcgccga
    23521 tacggggcgg cggggccgcg gtggtcgggg tgagcagcac gtcgtacccc ctcccgccgc
    23581 cgtgccccgc ctggtacggg tcgaagaacg cgccgatccg ccggtgctgg cgcacctccc
    23641 gggcgcgggc ggcccgcacc acccggccgc cgagccgcgt cccggtgcgc agggcgctgc
    23701 gggtgcgcgg gtccagcagc gccggttcgg ggtgggccgc ggccagttcc gcgatgccgg
    23761 cggtggcgcg ggggacgaaa gagaggccga tcagcccgta ccgggggcgg gcctcctcga
    23821 cgtggtggcc gagccgggcc agcgcctcgg caagcgcggt gacggcacgc acgacctcgg
    23881 ggtgcggtgc gttgcgggtg agggtgagcg gcgggcgcag ggcgaggccg atgcgcagtc
    23941 tgccgggatc ccggcgggcc gcggccgagg cgtcgacggc gggcgggcgg tgggggtcgc
    24001 cggggtgcgg tccggccgcg gcgtccagca gcagggcggc gtcggccacc gtacgcgcga
    24061 ggggtccgtt gacggtgagg ccctggaagg cgtcgctgtt cgggtggacg gagatccggc
    24121 cgcgctgcgg tttgatgccc acgagatggg tccaggcggc ggggatccgg atggaccccg
    24181 ccccgtcgga gcccagggcc gcggggacca gtccggcggc gacggccgcg gccgaaccgc
    24241 cggaggaacc gccgggcgtg cgggtggtgt cccacgggtt gcgggtggcg ccgaaggcgg
    24301 gcccctcggt gaagggccac tggcccagtt cgcaggagtt ggtcttgccg acgacgacgg
    24361 cacccgcggc ccgcagtcgg cggaccgcct ccccgtcggc ggtggcgggg ggcagcgcgc
    24421 cgtcgcagcc gaagtaggtg ggcataccgg cgacatcggt gtcgtccttg acggcgaccg
    24481 gcacgccgag cagcggcagc cgctcccccg aggcgagcct ccggtccgcc tcggcggcct
    24541 cggcgagtgc cgcctcggcc cgcaggtgcc ggaaggcgtt gagggtgggg tccgccgcct
    24601 cgatgcggct gagcgccgcc gcgacgagcg ccgtggacga ggtgtgcccg ccggccagct
    24661 gccggacggc gtccaccagt ccggcggcct cggccggggt gtccggccgc tgctttcgcc
    24721 cgtgcggtcc ggtgcgtccg acgggatccg ctgaggacat cgctgccgcc tcctcggtcc
    24781 gccggggcac cggcgcgccg gactccccgg ggccgcccag acggatctac cggagggtaa
    24841 cgaggtgggg cggtccgctc aagcaggccg gcccccctct gtccg
//
