LOCUS       NZ_CP043761            22571 bp    DNA     circular CON 27-OCT-2023
DEFINITION  Paenibacillus sp. 37 chromosome, complete genome.
ACCESSION   NZ_CP043761
VERSION     NZ_CP043761.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. 37
  ORGANISM  Paenibacillus sp. 37
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 7075616)
  AUTHORS   Nielsen,T.K., Hennessy,R.C. and Garcia,A.M.
  TITLE     Complete genome sequence of Paenibacillus sp. strain 37
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7075616)
  AUTHORS   Nielsen,T.K., Hennessy,R.C. and Garcia,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2019) Plant and Environmental Sciences, University
            of Copenhagen, Thorvaldsensvej 40, Frederiksberg 1871, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8-beta
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 137.0x
            Sequencing Technology             :: BGISEQ500; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/27/2023 04:50:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,538
            CDSs (total)                      :: 6,389
            Genes (coding)                    :: 6,340
            CDSs (with protein)               :: 6,340
            Genes (RNA)                       :: 149
            rRNAs                             :: 13, 13, 13 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 13, 13 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 25 of 49
            Pseudo Genes (incomplete)         :: 30 of 49
            Pseudo Genes (internal stop)      :: 11 of 49
            Pseudo Genes (multiple problems)  :: 14 of 49
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:46:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6781673
            Orig. end                         :: 6804244
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043761.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..22571
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iv"
                     /region_number="19"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     cand_cluster    1..22571
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22571
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12571](-)"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12571)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     gene            678..3119
                     /gene="nirB"
                     /locus_tag="F0220_RS29070"
     CDS             678..3119
                     /GO_function="GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0042128 - nitrate assimilation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="nirB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_BFD"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1175: pyridine nucleotide-disulfide oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018884620.1"
                     /locus_tag="F0220_RS29070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrite reductase large subunit NirB"
                     /protein_id="WP_105600420.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 3.1e-56, bitscore:
                     189.2, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 4.6e-12, bitscore:
                     44.6, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTKKLVLVGNGMAGIRTIEHILKLAPHAYEITVFGAEPHPNYN
                     RIMLSSVLAGGTSIEDIVINEWSWYEDNGIRVYPGDPVVQIDPKRKEVVSQNGVRATYD
                     ELIMATGSQAFILPLPGANKEGVIGFRDIKDCETMMAASQKYRKAAVIGGGLLGLEAAR
                     GLLNLGMDVTVIHINGHLMDRNLDLPAGLMLQRELEEQGMKFLLNKHTEEITGKHRVKA
                     LRFTDQTVLEADLVVMAVGIRPQIELARNTGLDVNRGVIVDDYMHTSIPGISAVGECAE
                     HRGIAYGLVAPLYEQGMVLAKRLAGAATEGYAGSVTSTKLKVSGVDVFSAGQFKDAADT
                     RSIRIQDDVDGVYKKMVIKDGQLIGAVLFGDTTDGASLFSLIKSGENISGREKEILLGV
                     PSGGSGSGPSVAERMASMPDDEIVCGCNGVTKASIGDAVLNKGCNTLGAIKSCTKASAS
                     CGGCKPIIENLLTYYAGDNVGEQTKEGICGCTSYDRDEIVAQIKEMGLKSVKEVMNVLG
                     WNEPEGCSKCRPSLNYYLGMIWPAEYRDERVSKFTNERYHANIQKDGTYSVIPRIYGGV
                     TSPAELIKIATVAEKYDVPMVKFTGGQRLDLLGVQKENLPKIWEELDMPSGFGYGKALR
                     TVKTCVGNTFCRFGTQDSIEMGIRLEKKLDKMVAPAKVKLAVSGCPRNCAEATIKDLGV
                     VAIDGAWEIHVGGNAGVKVRTAELLCTVKTDAEVEEWTYSYLQYYRENAKWNERTAAWI
                     ERVGLDHVKEALADRDVRLALIERLEVTLGHTVDPWKEIIEDEKLRKNFTPLSGAEPVT
                     H"
     gene            3136..3453
                     /gene="nirD"
                     /locus_tag="F0220_RS29075"
     CDS             3136..3453
                     /GO_function="GO:0008942 - nitrite reductase [NAD(P)H]
                     activity [Evidence IEA]"
                     /GO_function="GO:0051537 - 2 iron, 2 sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="nirD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018884619.1"
                     /locus_tag="F0220_RS29075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="WP_091012484.1"
                     /transl_table=11
                     /translation="MNKFRIGHLTDIDEKGARTFLIQDTEIAVFKLSDGSLHAVENRCP
                     HKGGKLSEGMVCGTAVHCPLHDWKIDLRNGKVHEPDEGCLNTYKTEVDGNSGEIFITIA
                     G"
     gene            3491..4372
                     /locus_tag="F0220_RS29080"
     CDS             3491..4372
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0015499 - formate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015724 - formate transport [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015255771.1"
                     /locus_tag="F0220_RS29080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="formate/nitrite transporter family protein"
                     /protein_id="WP_105600422.1"
                     /transl_table=11
                     /translation="MDFVKPAEVLQSMVEAGENKARMNRVQMLIRGFLAGAILAFATTL
                     AYTAVSQTSVGLAGALIFPAGFVIIILLGLELVTGNFAMLPLAVLKRRITWMDMLRNYF
                     WVITGHLLGCAFYALLYGLTITKMGTDMNNPLIQTLIQTSETKTLGYQHLGGAGIVLVI
                     IKAILCNWMVTLGAVMAMTSTSTLGKIIAMWLPITIFFAQGFEHAVVNMFVIPAGMMLG
                     AQVSVADWWLWNQIPVLVGNLIGGAIFTGLGLYAAHHWGNPVKLSSKLAAIQGGRSGLA
                     SSDAAPKLGTRS"
     gene            4369..5139
                     /gene="cobA"
                     /locus_tag="F0220_RS29085"
     CDS             4369..5139
                     /EC_number="2.1.1.107"
                     /GO_function="GO:0004851 - uroporphyrin-III
                     C-methyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0019354 - siroheme biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="cobA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TP_methylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811117.1"
                     /locus_tag="F0220_RS29085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="WP_105600424.1"
                     /sec_met_domain="TP_methylase (E-value: 3.6e-47, bitscore:
                     159.5, seeds: 87, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRGLVSIVGAGPGDPDLITVKALKRIQSADVIMYDRLVNDQLLA
                     EAREGALRIYCGKAPGLHSMSQEMIGRMLAAHAAEGKQVVRLKGGDPFIFGRGGEEALV
                     LAEAGIAFEIIPGITSAVGTSASSLIPLTHRGIASSFACVTGTGSDGSVSSVRWDLLAH
                     SVDTLVIYMGISQLPQIQHELLHHGKSGHTPAALIERGTTSEERIITGTLAELHSLSLS
                     HQVNNPALIMVGESVLIREQLLQMQQAANASMTG"
     gene            complement(5149..5787)
                     /locus_tag="F0220_RS29090"
     CDS             complement(5149..5787)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF025636.3"
                     /locus_tag="F0220_RS29090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR family transcriptional regulator"
                     /protein_id="WP_091012478.1"
                     /transl_table=11
                     /translation="MLIIEHPQDRRARRTQDAIIAAAVSLILEKGADALTIRDITERAD
                     YNRGTFYLHFPGKPELLQFILDDFMQGVGRAYAEPYAQLKEVDMTVLLPSTMPVFEYIE
                     AHQDIFRALITMHSDMGSRLCNMFRTYLTEDFVLVTEDSEWTINYDIMLSYLVSATVGV
                     IMHWAEIGFKYSAHYMGEQLTALINIKPTRLLIEPGQKGRTIHERMLLD"
     misc_feature    complement(5936..5949)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 21.52"
                     /tool="antismash"
     gene            5983..6750
                     /locus_tag="F0220_RS29095"
     CDS             5983..6750
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (7-169). E-value: 1.1e-13. Score:
                     43.4. Matches aSDomain:
                     nrpspksdomains_F0220_RS29095_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691632.1"
                     /locus_tag="F0220_RS29095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_091012476.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-34, bitscore:
                     117.0, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 2.8e-05,
                     bitscore: 21.8, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTYTHTAVITGAAGGIGKELARRLAERKINLVLVDLNEEAIQQ
                     TITDLNLDKEHVIAVKANVSQEADVKNYVQKALDAFGRIDYFANNAGIEGPTGLIEDLS
                     VEALDTVYNVNIRGVFLGLQNVIPVMKKQKSGAILNTSSLAGLMGAPAVSPYIMSKHAV
                     VGLTRTAANELAPYNIRVNAVLPGTINTRMMRQIEANSGNVEDYQSATVSAIPMGRYGE
                     PEEVAAVMNFLLSEEASYVTASLYTVDGGMMGQ"
     aSDomain        6004..6489
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_F0220_RS29095_PKS_KR.1"
                     /evalue="1.10E-13"
                     /label="F0220_RS29095_PKS_KR.1"
                     /locus_tag="F0220_RS29095"
                     /protein_end="169"
                     /protein_start="7"
                     /score="43.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TAVITGAAGGIGKELARRLAERKINLVLVDLNEEAIQQTITDLNL
                     DKEHVIAVKANVSQEADVKNYVQKALDAFGRIDYFANNAGIEGPTGLIEDLSVEALDTV
                     YNVNIRGVFLGLQNVIPVMKKQKSGAILNTSSLAGLMGAPAVSPYIMSKHAVVGLTRT"
     CDS_motif       6010..6069
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_F0220_RS29095_0001"
                     /evalue="3.00E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="F0220_RS29095"
                     /protein_end="29"
                     /protein_start="9"
                     /score="23.1"
                     /tool="antismash"
                     /translation="VITGAAGGIGKELARRLAER"
     gene            complement(6903..7373)
                     /locus_tag="F0220_RS29100"
     CDS             complement(6903..7373)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012792.3"
                     /locus_tag="F0220_RS29100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_167483726.1"
                     /transl_table=11
                     /translation="MIYRPSNKGDISRLLEIQKEVFEEDLQKYQDYDTNPACETWEKME
                     KSIEIAHHFTIFDRDDNILGAIDIRGNDERMHINKIFIKTECQNSGMGTKAMDFVQKEY
                     TSAKLWTLYTPHLSYRNHYFYEKMGFSKIKEVKVSDRLTLFKYEKYVLQTEV"
     gene            7578..8459
                     /locus_tag="F0220_RS29105"
     CDS             7578..8459
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR01716.1"
                     /locus_tag="F0220_RS29105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="Rgg/GadR/MutR family transcriptional regulator"
                     /protein_id="WP_105600425.1"
                     /sec_met_domain="TIGR01716 (E-value: 1.5e-29, bitscore:
                     101.6, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIGQLIQYVRKSKNLTQTELAEGIMISRPYLAKIENDRHQISSE
                     KLSMILEFCNVNYDEFLFMLNDYKLSPKMAAYKDVFDTYQSDNKNELAISKTHIYQTYE
                     ESKDIFYKHLFILCECIELDFNKEKIPINHCKEIADYLISVENWCYYELVLFNNFLFVF
                     PESTAMHLSKNLIKRSLMYKDLKSDNKILSSLLFNLIQLSINIEDFIHTDALLDTAKNV
                     FNDRTNFFEQTMINFYLGIRMITSNNFNEGEQHCRNSLKVFEVLKQDEMYNRYSAQLNN
                     ALFRYSNPTKSI"
     gene            complement(8751..9998)
                     /locus_tag="F0220_RS29110"
     CDS             complement(8751..9998)
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1202: major
                     facilitator transporter"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF019310.3"
                     /locus_tag="F0220_RS29110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="MFS transporter"
                     /protein_id="WP_091012472.1"
                     /transl_table=11
                     /translation="MSSFMQFPLNIKFRILSSFFSKTIGTATSPFLILYLTNYLNDVFL
                     GLLLILSISLNFISSIIGGYLSDIFNRKRFITTFQTVQIAMLSILTFELYFLEKNPQEG
                     VLLYCIVISYVLQGMIGGTYKPAYNALIMDSTNKDNRRDIYRFNYWTTNLSLAVGTSIG
                     GWFSSNHLISLYLTSIFILILVTIGFFIIIENDNQIFRKEVRQNNFFVNLFNNYKEALK
                     NKDWVIFLLGSAFIFSVEFSLIYYSNIRLARDFSQFSILGINISGIRMFSVLQLINTIL
                     VVFCTFQIGRVVEKWSTKNALLIGVFLYICGYSLISYNLNFYILILCVVIATIGELIFS
                     PNWQAAQIEFIPKDKRGSFSALSALSNVLALLMASGYLLLSGHLTLSIISILIFIIGFV
                     GLILVSLTLVLKNRLE"
     gene            complement(10001..12571)
                     /locus_tag="F0220_RS29115"
     CDS             complement(10001..12571)
                     /GO_process="GO:0031179 - peptide modification [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1070: lanthionine synthetase C family protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF017000.3"
                     /locus_tag="F0220_RS29115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lanthionine synthetase LanC family protein"
                     /protein_id="WP_091012470.1"
                     /sec_met_domain="Pkinase (E-value: 8.4e-11, bitscore: 40.2,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3e-17, bitscore: 60.9,
                     seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSDKKINVLNMYYDIYRYKEDQTYRDIIERSQKCEVKNGSYYLQ
                     VYFSDAYLPEFGWKIHISATPLNAEDILTIVNEYCGKNKVPFKFMKDAEILKRSLSKVW
                     SRSSSGKFITIYPKDTKQFLLVIDELYQLLKLYTGPFVLSDKRYKDCKVLYYRYGSMAA
                     TDQTLKNQNGDYIIVGPNKEQFIDEPQPYYQQPEWIKNPVTQKDDFSEDNQGLKNGRYS
                     VLDIISISNSGGVYRAFDKYLNKNVILKEARPGTVVLDNGLDAISLRHQEKEILQELLQ
                     SGGTSAPSIYDDFFEWEHYFISVEEIKGENLQEKLSSPWEYEHKTIRTMDYIEKGIKLF
                     KRILSALSDLHRLGVSVGDISLRNIMIDHRDQIRFIDFELGCSDKHRNDATILMGTSGF
                     RYRKYRDLNHRFQIDYEAIGLIMISYFFPTGALFDIDNKKIKEFLHLLSSQSLIPKELV
                     GIIQDLIFRSKEVDLPKIISTLDNMNSRHSFIDFKKIEPLENRLKEHLRILHQTLINEF
                     ISASGKQPFLMSDKLNGLMDGKLGLLLSIREIESVIQVDTFLPKEVISRFIRTINYKEP
                     DFFNGYLGYVYLLNQLGLDGEELTEDKIQNLLQSLETYTLHRGIAGLGIVLLSLEKEES
                     DNFRKYSVFIGERIVSVINNDQWDKLCNGSYTEYGFFNGLSGIIYYLCELNKRTSNEIF
                     ARCAQKMLDYMLENSLIGPNKEYVLMSDEDEHAFNASFLGNAGLILAISAYLDIESNPV
                     YEKKLLDLVDSTEKSIYADPSFGSGLAGELLVLLKVVQEKRVYIDLASFERIFNVMESF
                     ALSYNGYVYYPNSLLLNVDSSFYGGTAGIAYALAKLLKYVTEVD"
     gene            complement(12674..12775)
                     /locus_tag="F0220_RS32680"
     CDS             complement(12674..12775)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0220_RS32680"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="class III lanthipeptide"
                     /protein_id="WP_188310509.1"
                     /transl_table=11
                     /translation="MLKILNLQKMAKETKGKTLIAQAYPGTSWLLST"
     gene            complement(13009..13263)
                     /locus_tag="F0220_RS29120"
     CDS             complement(13009..13263)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012772312.1"
                     /locus_tag="F0220_RS29120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_223200022.1"
                     /transl_table=11
                     /translation="MMQYIADKTKASQANIALVLKHQQAYINKAHENAKGNDVDIDGDD
                     LADYILSRKDVKLDELTVESILDAEMDYLMDKGHAGYVD"
     gene            complement(13422..14780)
                     /locus_tag="F0220_RS29125"
     CDS             complement(13422..14780)
                     /GO_function="GO:0000156 - phosphorelay response regulator
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1003: sensor
                     histidine kinase"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691630.1"
                     /locus_tag="F0220_RS29125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="HAMP domain-containing sensor histidine kinase"
                     /protein_id="WP_105600427.1"
                     /transl_table=11
                     /translation="MFKKLRNRFLIVNLVSISIMMLVAFATIYTITYQNVQRETNMELY
                     KVSDFYHSPYNSSKMPRGEGGGLGTGSGSGASTSASGSGSDSLPSNAMSGNNEGPGGDP
                     NAPPARSISFMIKTDSQWQITDTHSRFDMDETFYTEALQKVDRDKVGDSERQTGQFALD
                     GTDWAYVVDTTGDGHMIVFIDVTAQQGILTNLIYTFAVVGLIMLIVIYFLSRYFANRSI
                     APVREAFEKQKQFIGDASHELKTPLAIINTNADVLLANQEDTIANQAKWLHYIKSETER
                     MTGLTNDLLYLTQMDDSRSTMIHAKFNMSDAVESIILPMEAVIFEKNISLDYNIEPNLT
                     VHGNSEQIKQVILILLDNAVKYCGPRGSVNVTLQKQNNDVTLAVSNTGEGIAPEHLDRI
                     FDRFYRTDSSRARKHGGHGLGLAIARSIVDQHKGELYARSVVGEGATFYVRLS"
     gene            complement(14780..15457)
                     /locus_tag="F0220_RS29130"
     CDS             complement(14780..15457)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1008: response
                     regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914719.1"
                     /locus_tag="F0220_RS29130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="response regulator transcription factor"
                     /protein_id="WP_105600680.1"
                     /transl_table=11
                     /translation="MRILIAEDEVHLAEAVSQILKKNNYSVDMVHDGRSGLDYAQSGIY
                     DLLLLDIMMPEMDGITVLKKLRSEGNHTPVILLTAKGELSDKVTGLDYGADDYIAKPFA
                     TEELLARIRAALRRKGEVVPEDGLKFGDMELNTTQLKLSVQGKAIKLNLKENELLELLI
                     TRKQAITSKEQIIEKLWGFDSEVEYNNVEVYISFLRKKLTFLNSTVRINTIRGVGYVLE
                     VTS"
     misc_feature    complement(15580..15595)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 22.16"
                     /tool="antismash"
     misc_feature    15589..15606
                     /note="TFBS match to ArcA, Repressor of carbon oxidation,
                     confidence: medium, score: 19.87"
                     /tool="antismash"
     gene            15711..16535
                     /locus_tag="F0220_RS29135"
     CDS             15711..16535
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691628.1"
                     /locus_tag="F0220_RS29135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="polyphosphate polymerase domain-containing
                     protein"
                     /protein_id="WP_091013215.1"
                     /transl_table=11
                     /translation="MAIEVFNRYESKYLLTDEQYAHFYNDLLKYMELDAYNKKHEYYSI
                     SNLYFDTPQDSLIRASLSKPKYKEKLRLRAYGIPEENAKVYLEIKKKVFGLVNKRRTAL
                     KLDEAYEFVRSGQAPELADYMNKQVVEEIKYFLRLYDLEPKVYLAYERKALFDKNSRDL
                     RITFDTNIRSRRYDLKLEQGDYGEPLVKDGRWLMEVKAEKTVPLWLSQLLCEHGLYRTG
                     FSKYGNEFRHLVRTTNLNYQSERILVPGTDFNPSIEQEQDKTIIERERVLYA"
     gene            16528..17208
                     /locus_tag="F0220_RS29140"
     CDS             16528..17208
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014368459.1"
                     /locus_tag="F0220_RS29140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF4956 domain-containing protein"
                     /protein_id="WP_091012463.1"
                     /transl_table=11
                     /translation="MLDSLFSSALTDTNLTFNNAVITIGLAIILGLIISLTYMKTNQAT
                     YSQSFTLTMVVLPVIVAIIILLIGSNIARAFSLAGAFSIIRFRSAPGDPKDIAYVLFTM
                     ASGLACGVGAFGYAVLFTIILCVLMFVLSRFNFGGKKSQLKTLKVTIPENLSYEEALNE
                     VFHTFNVPFDLKKIRTTELGSLYELVYSVTIHESVSQKEFLDAIRTRNGNLDISLTMSP
                     TTEY"
     gene            17235..19529
                     /locus_tag="F0220_RS29145"
     CDS             17235..19529
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019914722.1"
                     /locus_tag="F0220_RS29145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carbohydrate-binding domain-containing protein"
                     /protein_id="WP_105600428.1"
                     /transl_table=11
                     /translation="MKKNMITGSKLWSIAMITSLLAACSSPATTSTTANAATSTTGTTK
                     TVSVSEQTSVKYADLVSLDADDTNISWSEADSTAIKLNGTTATVTGSGAKAANGSVTIT
                     EAGTYVLSGELTDGQIVVNVADKGTVHLVLNGATIHDNDSAAIYIQKAGKAVITLEKGT
                     KNTVSDGKTYVYADATTDEPDAAIFSKADLTFNGAGQLTVTGNYNEGITSKDDLKIISG
                     SISVKAADDGIKGKDMVAIQVGTITIKAEGDGIKSTNDTDTTKGFVAIAGGTFDIQSGN
                     DGIQAETALVADGGTYNIVTAGGSANAPAKVEEGPFGGGGGWGGGTPPTDMGTPPDGEP
                     PADMPEMPNNSGNAGANTNSEAASSSANTAATTDTNADADTAATATESTSAKALKAGTD
                     LTVNGGTYTIDSMDDSLHSNNNVTVNDGTFNIQSGDDGIHADQELTINGGTITIAKSYE
                     GLEGAIITLNDGDVDVTASDDGVNAAGGETETTANTAASTDSATTATDAATTSNISVTE
                     TTGTTSTTDQASQGTAATQQGRGPGGMGAASNNEFHINGGTLTVNAGGDGLDSNGSITM
                     TGGTVIVNGPTDNGNGALDYDGTFVISGGYLVAAGSSGMAQGASDASTQNTIVMTFPAT
                     QKAGTLVHVQDSEGNNILTFAPAKDYQTVVVSSPDLKKDGSYVIYSGGTSTDKAVDGLY
                     TDGTYSGGTQVVAFQSTSNVTWVNESGVTTANTGMGGPGGGRGQGGFGGGRNRTQSGTT
                     SDSTGTTDSAK"
     gene            complement(19701..20279)
                     /locus_tag="F0220_RS29150"
     CDS             complement(19701..20279)
                     /EC_number="2.1.-.-"
                     /GO_function="GO:0008168 - methyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:1904047 - S-adenosyl-L-methionine binding
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691626.1"
                     /locus_tag="F0220_RS29150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="WP_105600430.1"
                     /transl_table=11
                     /translation="MFIIYLIPWLIAVVTLIGVISIVLVSWKNGISPMPTSGRVRQVVI
                     QEVNRIPGYGDVLEAGSGWGTLGLDVVRHCPGKRLTGIENSRIPLWSSQFIAYLSVRLR
                     RAKGKQHSLKGRLRFMRGDIYTSSYEHADCVICYLFPGAMNRLLDKFSRELPPGAKVIS
                     VCFALPGKEPLRTITCRDALRTKVYVYSF"
     gene            complement(20306..20977)
                     /locus_tag="F0220_RS29155"
     CDS             complement(20306..20977)
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691625.1"
                     /locus_tag="F0220_RS29155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FHA domain-containing protein"
                     /protein_id="WP_105600432.1"
                     /transl_table=11
                     /translation="MRETAKIVIRTPGQESDGSFAYVSQGRSITVGRYTGGSELDLSVY
                     NQMISKRHCRIHYDVQQQLWIEDLDSKNGTELNGQRLVPYEKYPFGEGDSLTLVNGLIQ
                     LRAEGDLGETREYRVSDLLGEGVRLQDHLQTVQIGEVEIPLSKKEYQLFKLLYSELDHF
                     VTREQIVAQVWPERSMLESEAVGIDEINSLIYRTNRKLGVHFTIKSVYKKGVYMKSHVP
                     E"
     gene            21207..21362
                     /locus_tag="F0220_RS32685"
     CDS             21207..21362
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0220_RS32685"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_017691624.1"
                     /transl_table=11
                     /translation="MNKKNIFIYVLLAFALSMTLTVLSRMNDDGGESLKGTSAAETSWL
                     QMKIQP"
     gene            21853..22455
                     /locus_tag="F0220_RS29160"
     CDS             21853..22455
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019639170.1"
                     /locus_tag="F0220_RS29160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="hypothetical protein"
                     /protein_id="WP_105600433.1"
                     /transl_table=11
                     /translation="MKKEIGVLMLSCIVFLSGCGGSGNPASVMQGSGESPSKQVTTQQN
                     NEYCSLERTSLDSETEKYFYGTWNVEKLLGFANSYNDASEYPTGQKFIGDEIIIKKDLF
                     SSKGIKNYSRYQTELRNPLYEFTATCNNSDSFYRLYKLDIPNLNKNDVVKAIGVSNPST
                     KISIPVSLSFFVVNNEKLILLSEATIFELKKISDKIN"
     misc_feature    22504..22518
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence:
                     medium, score: 21.5"
                     /tool="antismash"
     misc_feature    22523..22537
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: medium, score: 23.93"
                     /tool="antismash"
ORIGIN
        1 ccagcagtct ctccggtgtc agagggattg catcggacga atcagctatc gtcgactgta
       61 tacgaatgac caataaagat cgcatgatgg agcaatccct ccctaattac gtataattag
      121 aatcacatta tttaaagcgt taacacaaga aagcgctata tatgttatat tacctgacaa
      181 aaaaaacaga tcaatctgat tttataactg atttcgagat aataaataca acaatcatga
      241 cggatcgtcc tagtagccca aaagagtaaa acactaatta tgatacgttt tctatgcttt
      301 ttgtagtgcc cagtgcacta tatttcacca aaacattcat tttcatgaat atatatcctt
      361 aaaacctctt cgatcattcg tgttccaata aattcatgta aacataatta actttaaatt
      421 tcaaatactt ttttatgtta actatattga catggttgga tcgatctttt atagttaagc
      481 cataacaact ccatatttga atcgatcaca gttacaacgg cgtagctggt tgaaacggca
      541 atgaagcctg ttttgcaatc tcggagcaag ggatgcgtat gtatatgcgc agtcctccga
      601 ggcataacag gctttttcga ttttagagac aaggttttga ggcagtttgc agaatggacc
      661 taagggggct aatcataatg agtacaacga aaaaactggt gctggtcggc aatggcatgg
      721 cgggaatccg cacaatcgaa catatcctta agcttgctcc acacgcttat gaaattacag
      781 tcttcggcgc agagccgcat cccaactaca accggatcat gttatcttct gtactggctg
      841 gcggaacatc catcgaagat atcgtaatca atgagtggag ctggtacgaa gataacggca
      901 ttcgggtgta cccgggtgac ccggtcgttc agatcgatcc caagcgcaaa gaagttgtat
      961 ctcaaaatgg tgtacgcgca acctatgatg agctgattat ggcaaccggt tcacaagcgt
     1021 tcatcctccc tcttcccggc gctaacaagg aaggcgttat cggattccgc gatattaaag
     1081 actgcgagac catgatggca gcatcacaaa agtatcgcaa agctgccgtt attggaggcg
     1141 gattgctagg actggaagca gcgcgggggc tgctcaatct gggcatggat gtcacggtca
     1201 tccatattaa cggtcatctg atggaccgga acctggatct cccggcagga ctgatgctcc
     1261 agcgtgagct tgaagagcaa ggtatgaagt tccttttgaa caaacatacc gaagaaatca
     1321 caggcaaaca tcgagtaaaa gcccttcgtt tcactgatca aacggtactt gaagcggatt
     1381 tggttgtcat ggctgtcggg attcgccctc agattgaact ggctcgcaat accggcctcg
     1441 atgtgaatcg tggagtcatt gtagatgatt atatgcatac cagcatccct ggtatatctg
     1501 ccgtcggcga atgtgcagaa caccgcggta ttgcctacgg actggttgct ccattatatg
     1561 aacaaggtat ggtgctcgca aaacgcctgg ctggtgcggc aaccgaagga tacgcaggtt
     1621 cggtcacgtc cacgaagctc aaagtatctg gtgtggacgt attctctgcc ggacaattca
     1681 aagacgctgc agacactcgc agcattcgca ttcaggatga cgttgatggt gtgtacaaaa
     1741 agatggtgat taaggatggg cagctcattg gagctgtatt gtttggggat accacggatg
     1801 gcgcatcgct gttttccctc attaagagtg gagagaacat cagcggtcgg gagaaagaaa
     1861 ttttgctcgg tgtaccttcc ggtggttcag gctcgggtcc atctgtcgca gaacgcatgg
     1921 caagtatgcc agatgacgag atcgtctgtg ggtgtaacgg tgttaccaaa gcttccatcg
     1981 gggacgctgt tctgaataaa ggctgtaata cactcggtgc aatcaaatcc tgtaccaaag
     2041 cttccgcttc ttgcggtgga tgtaaaccga ttatcgaaaa cctgctcacg tattatgccg
     2101 gtgataatgt aggtgaacag accaaagaag gcatatgtgg ctgcacatcc tatgatcggg
     2161 atgagattgt tgcacagatc aaggaaatgg gactcaaaag cgtgaaggaa gtgatgaacg
     2221 ttctcggttg gaatgagccg gaaggttgct ccaagtgtcg tccgtccctg aattattatc
     2281 tcggtatgat ctggccggct gaatacagag atgagcgtgt atccaaattc accaatgaac
     2341 gttatcacgc caacattcag aaggacggta cctactccgt tattccaagg atctatggtg
     2401 gtgttacttc cccggcggaa ttgatcaaaa ttgcgactgt cgcagagaaa tacgatgttc
     2461 cgatggtgaa gttcacgggt ggacaacgac tcgatctgct cggtgtacaa aaggagaacc
     2521 tgccgaagat ctgggaagag ctcgatatgc cttccggttt tggttatggc aaggcgcttc
     2581 gtacagtgaa gacttgtgtt ggtaatacat tctgccgatt cggcacacag gattccattg
     2641 agatgggtat tcgtctggag aaaaaactcg acaaaatggt agctccagcc aaagtgaaac
     2701 tcgctgtctc cggatgcccg cggaactgtg ctgaagcaac catcaaggat ctgggtgttg
     2761 tcgccatcga tggtgcatgg gagattcatg ttggtggtaa cgccggagtt aaagttcgca
     2821 cagctgagtt gctctgtacg gtgaaaactg atgcggaagt ggaagagtgg acctactctt
     2881 acctgcaata ttatagagag aacgcaaaat ggaatgagag aacagcggca tggattgaac
     2941 gggtaggtct ggatcatgtg aaggaagcat tggcggatcg ggatgtacgt ctcgctctga
     3001 tcgaacgcct ggaagttacg ctgggtcaca cggttgatcc ttggaaagaa atcattgaag
     3061 acgagaaatt gcgtaaaaac ttcaccccac tgtccggtgc cgagccggta actcactaga
     3121 aacggaggaa cagcgatgaa caaattccgg attggacact tgacggatat tgatgaaaag
     3181 ggtgcacgga ccttcctgat acaggatacc gaaattgcag tcttcaaact gagcgacgga
     3241 agtctgcacg ccgtcgagaa tcgctgccct cacaagggcg gcaagctgtc ggaaggcatg
     3301 gtgtgcggga cagcggttca ttgtcctttg catgattgga agattgatct gcgtaacggt
     3361 aaggtacacg agccggatga aggctgcttg aatacctaca aaacagaagt ggacggcaac
     3421 agcggagaaa tcttcatcac aattgcgggt taaaggctag agataccctg acatcaagga
     3481 ggcgtgcgct atggattttg ttaaacctgc agaagtgctg caatcgatgg tcgaagctgg
     3541 tgagaacaaa gccagaatga atcgggtaca gatgctgatc cgcggttttc tggcaggggc
     3601 tatcctcgcc tttgcaacca cattggcata taccgctgta tctcaaactt ccgttggttt
     3661 ggcaggtgca ctgatattcc cggctggatt tgtcatcatt attctgctgg gtctcgaatt
     3721 ggtgacagga aactttgcga tgcttccact cgcagtgttg aaacgcagaa ttacatggat
     3781 ggatatgctc cgaaattatt tctgggtgat cacaggacat ctgctcggat gtgcattcta
     3841 tgctctgtta tacggcttga ccattaccaa gatgggtacg gatatgaaca accctctaat
     3901 tcaaacgcta atccagacca gtgaaaccaa aacattggga tatcagcact tgggcggggc
     3961 tggcattgta ctggtcatca tcaaagccat tctatgtaac tggatggtca cactcggggc
     4021 agtgatggcc atgacgtcca cttctacact gggtaaaatc atagcgatgt ggctgcccat
     4081 tacgatattt ttcgctcagg gatttgagca tgctgtggta aatatgtttg tcattccggc
     4141 aggcatgatg ctcggcgcac aggtgagtgt cgctgactgg tggctgtgga atcagatccc
     4201 ggtgttggtg ggtaacctca ttggcggagc tatattcaca ggcctcggtt tatatgctgc
     4261 ccaccactgg ggaaatccgg taaagctctc gtccaaactg gcagccattc agggtggtcg
     4321 ttcaggattg gcaagttctg atgctgctcc gaaattgggg acacgatcat gagccggggc
     4381 ctggttagta ttgttggcgc tggtcctgga gacccggatc tgattacggt aaaagccctg
     4441 aaacgtattc agtcggcaga tgtcattatg tatgatcggc ttgtgaatga tcaattgctc
     4501 gctgaggctc gcgaaggagc actccgcatc tactgcggca aagccccagg gcttcactcc
     4561 atgagtcagg agatgattgg acggatgctg gctgcgcatg cagcagaagg caaacaagtt
     4621 gtacgactca agggaggcga tccgtttatc tttggccgtg gtggtgaaga agcgcttgtg
     4681 ctggcggaag cagggattgc atttgagatt attcctggca tcacttcggc tgttggcacg
     4741 tccgcttcct cccttattcc gttaacccat cgcgggatcg cttcatcctt cgcatgtgtc
     4801 acgggaactg gcagtgacgg aagtgtatca tcggttcgct gggatctact cgctcatagt
     4861 gtggacacac tggtcatcta catgggtatt agccaactgc cccagatcca acatgaattg
     4921 cttcaccatg ggaaaagtgg acacacccct gcggctctaa tcgaacgggg aaccacttcg
     4981 gaggaacgca ttattaccgg cacacttgcc gaactccact ccctctccct gtcacatcaa
     5041 gtgaataacc cggcattaat tatggtcggc gagtccgtcc tgatccgcga acaactgctt
     5101 cagatgcaac aggccgctaa tgcctccatg accggataat ccggtacttt aatccaacag
     5161 catacgctcg tgaatagtcc gacccttctg ccctggttca atcagcagac gggtcggttt
     5221 gatgttaatc agcgccgtaa gttgctctcc catataatgc gcagaatatt tgaacccaat
     5281 ctccgcccaa tgcatgatta cgcctacagt tgcagatacc agataactta acatgatgtc
     5341 gtaattaatc gtccactcac tatcctcggt caccaataca aaatcttcgg ttagatacgt
     5401 tctaaacata ttgcacagcc gggaacccat atccgaatgc atcgttatta atgcacgaaa
     5461 gatatcctga tgggcttcaa tatattcgaa tacaggcatc gtggatggca gcaacacagt
     5521 catgtccact tccttaagct gtgcgtatgg ttctgcatat gctcgcccca ctccctgcat
     5581 gaaatcatcc agaatgaact gcaacaactc cggtttgccg ggaaaatgta aatagaaggt
     5641 tccacggttg taatccgccc gctccgtaat atcccggatt gtgagggcat ccgctccctt
     5701 ctccaatatc aaagaaaccg ccgcagcgat gatcgcatcc tgtgttcttc gtgctctccg
     5761 gtcctgagga tgttcaataa tcaacatttt cgcctccttt gttcattatt gtaatataaa
     5821 taaacaccgc ctacacctct gtccgatagc tgacatatgc gctgtcaatg attattgtca
     5881 cattgctatg tatatcttaa cattgagaca ggaaagatag acgacaggtt gaaacttttt
     5941 ttgagaaata cctgccaata atgaataagg agcgaatata tcatgagtac aacgtataca
     6001 catacagccg taattacagg agcagccgga ggcattggta aagaattggc acgccgcctt
     6061 gcagagcgca aaatcaactt ggttctggtg gacctgaatg aagaagccat ccaacagacg
     6121 attactgatc tgaacctcga caaagagcac gtcatcgccg taaaagcaaa cgtatcccag
     6181 gaagcagacg tgaaaaacta tgtgcaaaaa gcactggatg catttggccg aatcgattat
     6241 tttgccaaca atgccggaat tgaaggtcca acagggctga tcgaagacct gagtgttgaa
     6301 gcactcgaca ctgtatataa cgtcaacatt cgtggcgtat tcctgggtct gcaaaatgtc
     6361 attccagtga tgaaaaaaca aaaatccggt gcgattctaa atacctcttc ccttgcgggt
     6421 ctgatgggcg cacctgccgt atctccatat attatgtcca aacatgccgt agttggtctc
     6481 acgcgtaccg ctgcaaatga attggcacct tacaatatcc gggttaacgc tgtattgcca
     6541 ggcacaatca acacacgtat gatgcgccaa atcgaagcca attccggcaa cgtggaagat
     6601 tatcaatctg ctacggtatc tgccattcca atgggccgtt acggtgaacc ggaagaagtc
     6661 gctgcggtga tgaacttcct gttgtccgaa gaagcatcct atgtaacagc ttccctctac
     6721 actgtagatg gcggtatgat gggtcaataa gatgaatcaa atagattcta gatacctata
     6781 aactttgtaa ttgagtccta ccttgttgaa catttagata ctgtaagaac tataaaaaac
     6841 actcttaaag agggcgttac cctcattcta agagtgtttt tttcgtataa ttcttaggga
     6901 aatcatactt ctgtctgcag aacatatttt tcatatttaa agagtgttag tctatctgaa
     6961 accttaacct ctttaatctt agagaatccc attttttcat aaaaataatg atttctatag
     7021 cttaaatgtg gagtatatag agtccataat tttgcactgg tatattcttt ttgaacaaaa
     7081 tccatcgctt ttgtgcccat accagaattt tgacattctg ttttgatgaa tattttattt
     7141 atatgcatcc tttcatcatt ccctctaatg tcaatggctc caagaatatt atcatctcta
     7201 tcgaaaattg tgaaatgatg cgcaatctct atacttttct ccattttttc ccacgtttca
     7261 catgcaggat tggtatcgta atcctgatac ttctgtaaat cttcttcaaa aacctccttc
     7321 tgaatttcga gcaaccttga gatatctccc ttattggatg gacgatatat cattagaata
     7381 cctcctgcgt cgtcttctat ggatttgtaa tccaccatat ataatcactt aaaaatgata
     7441 gcataattat acctacactg taggatgctt tataacttag tttcttcact agaaatcgcc
     7501 tcctataaaa gagtatacta ggtaaatatt gcaataacat tttttgtaat aaatattata
     7561 catctaagga gagtcacatg aaaatcggcc aacttatcca atatgttcgt aaaagtaaaa
     7621 accttacaca gactgagtta gcagagggta tcatgatttc aagaccatat ctggccaaaa
     7681 ttgaaaatga ccggcatcaa atttcttctg aaaaactttc aatgattctt gaattttgca
     7741 atgttaatta tgacgagttc cttttcatgc ttaatgacta taagttaagc cctaaaatgg
     7801 ctgcatataa agatgttttt gatacatatc aatcggataa taagaatgaa ctagctatct
     7861 caaaaacaca tatatatcaa acctacgaag aatctaagga tatcttttat aaacatctat
     7921 ttattctatg tgagtgtata gaattagact ttaacaaaga aaaaattcca atcaatcact
     7981 gtaaagaaat tgcagattat ttaattagcg ttgaaaattg gtgttattac gaattagtac
     8041 ttttcaataa ctttttattt gtttttcctg aatccactgc tatgcattta tctaagaatt
     8101 tgatcaaacg ttctttaatg tacaaagatt taaagtctga taataaaatt ctgagttctt
     8161 tattatttaa cttaattcaa ttaagtatta atatcgaaga ctttattcat accgatgctt
     8221 tacttgatac agcaaagaat gtattcaatg atagaactaa tttttttgaa caaaccatga
     8281 ttaactttta tttaggaatt agaatgatta catcaaacaa tttcaatgag ggtgaacaac
     8341 attgcagaaa tagcttgaag gtatttgaag ttttaaaaca agatgagatg tataacagat
     8401 atagtgctca actaaataac gctctattca gatacagcaa ccctactaag tcaatctaag
     8461 aatataggtt tatattgcaa gttaatattc ataaatactt atagattgaa ctaaagaatc
     8521 agttgttcaa ctctcaattc ataaccaata tgaatcaaat gtccaaagtt tctcgcagcc
     8581 acaacataag gttttaatcc tccttttcgg ttatggtaag gttattaagt taagcagatt
     8641 ccacaaacgt ggaatgcgta gctgtaatct aacagaaaac tattcatgga accgccacct
     8701 tttggagttt gtagtaatac aaacgatgtt tcaaggttgc ggttcttttt ctactctaat
     8761 cgatttttca acacaagcgt taatgatact agtattaatc caacaaaccc tattataaat
     8821 atcagtatgc ttataattga taaagttaag tgacctgata ataatagata accacttgcc
     8881 attaatagag ccaacacatt tgataatgct gacaatgcgg aaaaagatcc ccttttgtcc
     8941 tttggaataa actctatttg tgctgcctgc caattcggag aaaaaataag ctctccaatg
     9001 gttgcaatga ctacacagag gataagtata taaaaattta ggttatatga aattaagctg
     9061 taaccacata tatatagaaa tacgccgatt aaaagagcat tttttgttga ccatttctca
     9121 actactctac caatttgaaa agtgcaaaaa acaactaaaa tagtgttaat caattgtaaa
     9181 acagaaaaca tcctaatgcc tgaaatgtta attcctaata tactaaattg agagaaatcc
     9241 cttgcaagcc ttatattaga gtagtaaatc aatgagaact caacagaaaa aataaatgcg
     9301 ctacccaata aaaaaattac ccaatcctta tttttaagtg cctccttata attgttaaaa
     9361 agattaacga aaaagttgtt ttgtctaact tcttttcgaa atatttggtt atcattttct
     9421 ataataatga aaaagccaat tgttactaga attaaaataa atattgaagt taagtacaaa
     9481 gatattaaat ggttactaga gaaccaacct cctatacttg tacctacagc cagcgacaag
     9541 ttagtagtcc aataattaaa tctatagata tctcttcgat tatctttatt tgtcgagtcc
     9601 ataattaaag cattgtatgc aggcttataa gtccccccta tcataccttg tagtacataa
     9661 gaaataacta tgcaataaag cagaactcct tcttgagggt ttttttcaag aaagtagagt
     9721 tcaaaagtca atatagacag cattgctatc tgaacagttt ggaaggtagt tataaaccgc
     9781 ttcctgttaa aaatatctga caggtaacca ccgataatac tggatatgaa attcaaagaa
     9841 atactgagta taagaagaag acctaagaaa acatcgttca aataattagt taaatataaa
     9901 attaaaaaag gagaagttgc agttccgatt gttttagaga agaaggagct aagtatacga
     9961 aatttaatat ttaatgggaa ttgcatgaat gaactcatac tcaatctacc tcagtaacat
    10021 acttcaataa ttttgcaaga gcgtaagcaa ttccagctgt tcccccataa aatgaactat
    10081 caacattcaa gagaagacta ttaggataat aaacataacc attgtaactt aaggcaaacg
    10141 actccataac attgaatatt cgctcgaaac tagctaagtc aatgtatact cgcttttctt
    10201 ggactacctt taaaagaacc aaaagttctc cagccagacc actcccgaag gaaggatcag
    10261 catatataga cttttcagta ctgtccacta agtctaataa ttttttttcg tataccgggt
    10321 tgctctctat atccaaatag gccgagatag ctaatataag tccagcattc cctaaaaagc
    10381 tagcattaaa ggcatgctca tcctcatcac tcatgagtac atactcctta ttagggccaa
    10441 ttaaggaatt ttcaagcata tagtcaagca ttttttgtgc acatcttgca aaaatttcat
    10501 tactagtccg tttattcaat tcacataaat agtaaattat acctgataat ccgttaaaaa
    10561 atccatattc tgtataagac ccattacaca acttatccca ttggtcattg ttgattacag
    10621 atacaattct ttctcctata aatacagaat actttctaaa attatccgac tcttcttttt
    10681 ctaaagagag aagtacaatt cccaacccag caattccccg atgtagagta tacgtctcaa
    10741 gcgattggag caagttctgt attttatctt cggtgagctc ttccccatct aatcccaatt
    10801 gatttaataa ataaacatat cctaaatacc cattaaaaaa atctggttct ttgtaattta
    10861 tagttcttat aaatctgcta ataacctctt tgggtaaaaa agtatcaact tgaattacac
    10921 tttcaatctc tcttatacta agtaacaagc caagctttcc atccattaac ccattaagct
    10981 tatcactcat taagaatggc tgtttacctg aggcagaaat aaattcatta attaatgtct
    11041 gatgaagtat tctcaaatgt tccttcaacc ggttttcaag aggctctatt tttttgaaat
    11101 ctatgaaaga atgccttgaa ttcatattat ccaatgtgct tatgattttt ggtagatcga
    11161 cttcctttga tcgaaaaata agatcttgaa ttatacctac tagctcctta ggtattaaag
    11221 attgtgaact caacagatga aggaattctt ttattttttt attatcaata tcaaacagtg
    11281 cacctgttgg aaaaaagtaa ctaatcatta taagcccgat cgcttcataa tcaatttgaa
    11341 atctgtgatt taaatctctg tatttccggt aacgaaaacc ggacgtaccc attagtatag
    11401 tagcatcgtt tctatgttta tcactacaac caagctcgaa gtcaataaaa cgtatttgat
    11461 cccggtgatc aatcataata tttcttagtg aaatatcccc aactgacaca cctaaacggt
    11521 gtaaatcact cagtgcagat agaatacgct taaatagttt aattcctttt tcaatgtaat
    11581 ccatagttcg aatagtttta tgttcatatt cccatggtga acttagtttc tcttgtaagt
    11641 tttcaccttt tatttcttca acactaataa agtaatgttc ccattcaaaa aaatcatcat
    11701 atattgaagg agcactcgtt ccacccgatt gcaacaattc ttgcaaaatt tctttttctt
    11761 gatgcctcaa ggaaatagca tctagcccat tatctaaaac aaccgtaccc ggtctagcct
    11821 cctttaagat tacattttta tttaagtact tatcaaacgc tctataaaca ccaccgctgt
    11881 tagagattga aataatatct aatacactgt atcttccatt cttaagtcct tgattatctt
    11941 ctgagaaatc atctttttga gttactggat tttttatcca ttctggttgc tggtaataag
    12001 gttggggttc atctataaat tgctctttgt tgggaccaac tataatataa tcaccgtttt
    12061 gattttttaa agtttggtct gtagccgcca tgctaccata acgatagtat agtaccttac
    12121 aatccttata tcttttatcc gataatacaa aaggcccagt atataattta agcaactgat
    12181 ataattcatc aattactaac aaaaactgtt ttgtgtcttt tggataaata gtaataaatt
    12241 taccagaaga gcttctactc caaactttag aaaggcttcg ctttaatatt tctgcatctt
    12301 tcatgaactt aaatggcacc ttatttttgc cgcagtattc attcacaatc gtcaatatat
    12361 cctctgcatt taatggtgtt gctgaaatat gaattttcca tccaaattcc ggcaaataag
    12421 catcagaaaa ataaacttgt aagtaatagg acccattctt cacttcacac ttttgggatc
    12481 tttcaattat atctctataa gtctgatctt ctttatatct ataaatatca taatacatgt
    12541 tcagaacatt gattttctta tcacttagca actttccatc cctccataaa aattaactaa
    12601 ttaatataaa aaaagactct ccttagagat tcctctaata ggaaagtctt ttcttatgta
    12661 attgagaaaa ttattaagtg ctcaacagcc agctagtacc tggataggct tgagcaatca
    12721 acgttttacc ctttgtttct ttagccattt tttgcaggtt cagaattttc aacatactaa
    12781 tcaccccttt ctgtttgtac tcccaacaat taattggtat atatacattt aactacaaat
    12841 atatatattt ttattttttg taataaatat tacacattct tatctctgtt tccaaaaact
    12901 aaatttttct ttttggaatc agtcatctac catcaacaaa taaatcgacc tcctaatagt
    12961 actgaaggtc gatttataat aaactatgtc ataatattga aaacagatct aatcgacgta
    13021 ccctgcgtga cccttgtcca tcagatagtc catttcagca tccagaatgc tttccacggt
    13081 cagctcatcc agcttcacat ctttgcgact aaggatgtag tcagccagat catcgccgtc
    13141 aatatccaca tcgttacctt tggcattttc gtgcgccttg ttgatgtacg cttgctgatg
    13201 cttcagcaca agagcgatgt tcgcttggct tgccttcgtt ttatctgcaa tatattgcat
    13261 catttcttgt tcattaattg cgtttgcttc tgccacgttc agttcatctc cttgattcat
    13321 acatactgtt gccattgtag cataggttaa cccattacag gcagaactta tccctgtaga
    13381 acgattatag atccagagtg aagaaacgca tcactccgcc cctacgacaa ccgtacgtaa
    13441 aatgtagcac cctctccgac tacacttcgg gcgtatagct ctcctttgtg ctgatccaca
    13501 atagaacgag caatcgccag ccccagacca tgcccaccat gtttgcgggc tctggacgaa
    13561 tccgtacgat agaatcgatc aaagatccga tccagatgtt ctggtgcaat gccctcaccc
    13621 gtgttggaca cggccagcgt gacatcatta ttctgtttct ggagcgtaac gtttacggac
    13681 cctctgggcc cgcaatactt caccgcatta tcgagcagga tcagaatgac ctgtttgatc
    13741 tgctcactgt tcccatgaac cgtaagattc ggctcaatgt tgtagtcaag ggagatgttt
    13801 ttctcaaaaa taacggcttc cattggcaat ataatacttt ctaccgcatc gctcatatta
    13861 aacttcgcat gaatcatcgt cgagcgtgag tcatccatct gtgtcagata gagcagatca
    13921 ttcgtaagtc cggtcatgcg ttcggtttcc gatttgatat aatgaagcca cttcgcctga
    13981 ttcgctatgg tatcctcctg atttgcaagc agcacgtcag cattggtatt gatgatcgcc
    14041 agaggggtct tcaactcatg tgaagcatca ccgatgaatt gtttttgttt ctcaaatgct
    14101 tctctaaccg gtgcaatgga gcgattcgca aaataacggc tcaggaagta gatcacaatc
    14161 aacatgatta atccaacaac agcaaaagta tagatcagat tcgtaagaat gccctgttgt
    14221 gccgtcacat caatgaatac gatcatatgc ccgtcaccgg tcgtatcaac tacataggcc
    14281 cagtccgttc catccagcgc aaattgtcca gtctgccgtt ccgaatcacc aactttatcc
    14341 cgatccactt tttgcagcgc ctcggtgtag aaggtttcgt ccatatcaaa acgggaatgg
    14401 gtatccgtga tttgccactg gctatccgtc ttgatcatga acgaaatgga acgtgccgga
    14461 ggtgcattgg ggtctccacc gggtccttca ttgttaccac tcatggcatt ggatggtagc
    14521 gaatctgaac ctgaacctga agcacttgta ctagcgcctg atccagaccc cgtccccaga
    14581 cccccacctt ccccgcgcgg catcttggat gaattataag gactgtggta gaaatcagac
    14641 accttgtaca actccatatt tgtctcacgt tgcacattct gatacgtaat cgtatagatc
    14701 gtcgcaaatg ccaccagcat cataatcgat atggacacca gattcacgat caggaatcga
    14761 ttccggagtt tcttgaacat caggacgtca cctcaagcac ataccccaca ccccgaatcg
    14821 tgttaatgcg aacagtcgag ttcaggaagg ttaatttttt gcgtaaaaac gagatgtaca
    14881 cctccacatt gttatactcc acttccgaat cgaatcccca caacttctcg ataatctgct
    14941 ctttggaggt aatcgcctgt ttgcgcgtaa tcaacagctc cagcagttca ttctccttca
    15001 gattcagctt gattgccttc ccctgtacgc tcagcttcaa ctgagttgtg ttcagctcca
    15061 tgtcgccgaa tttcagtccg tcctccggaa caacttcgcc cttccgccgt aaggctgcac
    15121 gaatccgggc cagtaattct tctgtggcga agggcttggc gatataatca tcggcaccat
    15181 aatcgaggcc tgtgaccttg tccgataatt cacctttggc cgtaagcaga atgactggcg
    15241 tatgattgcc ttcactgcga agtttcttca ggacggtgat tccgtccatc tctggcatca
    15301 tgatgtcgag cagtaacagg tcgtagatgc cgctctgcgc ataatcgagt cctgatctgc
    15361 cgtcgtggac catgtccacg gagtagttgt tttttttcaa aatctgcgat actgcctctg
    15421 ccaaatgaac ctcatcttcc gcaattaata ttctcatcat ctattcattc ctctgcttga
    15481 attattcgtc ttcataaacg ctgtatggta tcacccattc tatcaattga accttgaatc
    15541 aatcttaatt cattttgtgt atgcccacta ttataggaag gtaaaaaaat gttaacgcaa
    15601 tgtaaaacca tttaagattc attcaaggtt ggccctctaa gatacagaca tggaagcaat
    15661 acacgatgca tcaaaacata caacccacca acgaaaggac tgaatcccac atggcaattg
    15721 aagtattcaa ccgatatgag agcaagtacc ttctgacgga tgaacagtac gcccatttct
    15781 acaacgacct gctgaaatac atggaactgg atgcctacaa caagaaacat gagtactact
    15841 ccatcagtaa cctgtatttc gatactccac aggattccct gattcgcgcc agtctctcca
    15901 aaccaaaata caaggagaag ctgagactgc gggcgtatgg aatacctgaa gagaatgcca
    15961 aagtgtatct ggagatcaaa aagaaagtct ttggcctggt gaacaagcgc agaaccgcct
    16021 tgaagctgga tgaagcgtac gaattcgttc gttcaggaca ggcaccggag ctggcagact
    16081 atatgaacaa acaggttgtg gaagagatca aatacttcct tcgcctctac gatcttgaac
    16141 cgaaagtgta tctggcgtat gaacgcaaag cactctttga caagaacagc cgggatctcc
    16201 gcattacctt tgacaccaac attcgcagcc gcagatacga tctgaagctg gaacagggag
    16261 attacggtga accgctcgtg aaggacggaa ggtggctgat ggaagtgaaa gccgagaaaa
    16321 ccgttccgct gtggctgtcg caactgctct gtgagcatgg tctctaccgc actggattct
    16381 ccaaatacgg caacgagttc agacatctgg tgagaacaac caacctgaat taccagtcgg
    16441 agcgcattct tgtaccaggt actgacttca acccatccat agaacaagaa caagataaaa
    16501 cgattataga aagagagcgt gtcctatatg cttgattcac tattcagttc cgcccttacc
    16561 gataccaacc tgacgtttaa caacgcagtc atcaccattg gtcttgccat cattctgggg
    16621 ttaatcatca gcctcacgta catgaagacc aaccaagcca catactccca gagcttcacc
    16681 ctaacgatgg tcgtcctgcc cgtcattgtc gccatcatca tcctgctcat cggcagcaac
    16741 attgctcgag cattcagctt ggcaggtgcc ttctcgatca ttcgtttccg cagtgcacct
    16801 ggtgatccaa aggatattgc ttatgtattg ttcacgatgg cttccggtct tgcctgcggt
    16861 gtaggtgctt ttggatacgc agtgctgttc acgattatcc tgtgtgtgct gatgtttgtc
    16921 ctgagtcgct tcaacttcgg cggcaagaag agtcagctga aaacgctgaa agtcaccatt
    16981 cctgagaatt tgagctatga agaagcactt aatgaagtgt tccatacatt taatgtacct
    17041 tttgacctga aaaagatcag aacgaccgag ctcggcagtc tgtatgagct ggtctacagt
    17101 gtaaccatcc acgaaagtgt tagccaaaag gaattccttg atgccatccg cacacggaac
    17161 ggcaacctgg atatctcgtt aaccatgagt ccaacaacgg aatattaatt cttaattcga
    17221 agggaacgat ctatatgaag aaaaacatga taacaggcag caaactgtgg tccatcgcca
    17281 tgattaccag cctactcgct gcatgcagtt caccagcaac gacaagcaca accgccaatg
    17341 ccgcaacgtc aacgacagga acaaccaaaa cggtatcggt cagcgagcaa acctctgtga
    17401 aatatgcaga tctggtctct ctggatgctg acgataccaa cattagctgg agcgaggcag
    17461 attccacagc gattaagttg aacggcacaa cggcaacggt aaccggttcg ggcgccaaag
    17521 cagccaatgg ctcagtaaca attacggaag caggtactta tgtacttagc ggtgagctaa
    17581 ccgacggtca gatcgtggtc aacgttgccg ataagggcac cgtacatcta gtattaaacg
    17641 gagctacgat ccatgataat gacagtgccg caatctatat tcagaaggcc ggtaaagcgg
    17701 tgattacact cgaaaaagga accaagaata ccgtatccga tggtaaaacg tatgtgtacg
    17761 ctgacgctac aacagacgaa ccggatgctg caatcttcag caaagcggat cttacgttca
    17821 acggtgcagg tcaattgacc gtcacaggta actataatga agggattacg agcaaggatg
    17881 atctgaagat catcagcggt agcatcagtg tcaaagcagc cgatgacggt atcaaaggta
    17941 aagacatggt cgctattcaa gtgggtacga ttaccattaa agccgaaggt gacggcatca
    18001 aatccaccaa tgacacggat accaccaaag gtttcgttgc catcgcagga ggtaccttcg
    18061 atattcaaag tggtaacgac ggtattcaag ccgaaaccgc acttgttgcg gatggcggca
    18121 catacaacat tgtgactgct ggcggtagcg ccaatgctcc agccaaagtc gaagaaggtc
    18181 catttggtgg cggcggtgga tggggtggcg gaacacctcc aaccgatatg ggcacaccac
    18241 cagatggcga acctcctgca gatatgccgg agatgcctaa taacagcggc aatgcaggtg
    18301 ctaatacaaa cagcgaagca gcgtccagct ctgccaacac agcagcaaca accgatacca
    18361 atgccgatgc ggacactgct gcaacagcaa ccgagtccac aagtgccaaa gcactgaaag
    18421 caggtactga ccttacggtg aatggcggta cgtataccat tgattccatg gatgattccc
    18481 tgcacagcaa caataacgtg acagttaacg acggaacatt caacattcaa tccggtgatg
    18541 acggcattca tgccgatcag gaactgacga ttaacggtgg caccatcacc attgcgaaga
    18601 gctatgaagg acttgaagga gcaatcatca ccctgaacga tggggatgtg gatgtaacag
    18661 catccgatga tggcgtcaat gctgcaggtg gcgagacgga aacaactgcg aatacagcgg
    18721 caagtacaga tagcgctact acagcaaccg atgctgctac gacatccaac atctctgtaa
    18781 ccgaaacgac gggtacaaca tcgactaccg atcaggcatc ccaaggtaca gctgctactc
    18841 agcaaggacg tggaccgggc ggaatgggag cggcgagtaa taacgagttc cacattaacg
    18901 gcggtacact taccgtgaac gcaggtggtg acggactgga ttccaatggt tccattacca
    18961 tgaccggtgg tacggttatt gtgaacggac caacggataa cggtaacgga gcattggatt
    19021 atgacggtac atttgtaatc agcggtggat acctcgtggc tgccggaagc tctggtatgg
    19081 cacaaggagc atccgatgcg tctacgcaaa ataccattgt aatgacattc cctgcaacgc
    19141 aaaaagctgg aacacttgta catgtacaag acagtgaagg caacaacatt ctgacgtttg
    19201 ctccggcaaa agattatcaa actgtggttg tcagctcccc ggatctgaaa aaagacggct
    19261 cctatgtaat ctactccggt ggtacgtcta cagataaagc agtggatggg ctctacacag
    19321 acggtactta cagtggcgga acacaagtgg ttgcattcca atcgaccagc aatgtaactt
    19381 gggtgaatga atctggtgtg accacagcca atacaggtat gggtggtcct ggcggaggtc
    19441 gtggccaagg cggattcgga ggtggcagaa atcggacgca atccggtaca acatccgaca
    19501 gcacaggcac tacggattct gcaaaataat catcatgtcc tgagccatag cgcataactc
    19561 gcttctcagg cgcaggcgaa acaaaaaagg ctccgaattc acgttatgtg agttcggagc
    19621 tttctttcgt tattcttctg gaccagaatt acagggaatc atagccctct gcccaaggtg
    19681 cagcggatgt actctttttc tcagaacgag tatacataca ccttggtacg caaggcatcc
    19741 cggcatgtaa tcgtacgtag tggttcctta cccgggagcg caaaacagac actaatcacc
    19801 ttggcacccg gcggaagctc ccgactgaat ttgtccagaa gtcggttcat cgctcccgga
    19861 aacagataac agatcacaca atccgcatgt tcataggaac tggtgtatat atccccgcgc
    19921 atgaagcgca gcctaccctt aagagagtgc tgttttccct tcgctcgacg taagcgaaca
    19981 ctgagatacg caatgaattg ggaagaccat aagggaattc tcgaattctc aatcccggtc
    20041 agccttttac caggacagtg ccttacaaca tccagtccca gtgtacccca tccggaacct
    20101 gcttcaagca catccccgta cccgggaatc cggttcacct cttgaatgac cacctgccta
    20161 acgcggccgg atgtgggcat cggggaaatc ccgtttttcc aactaacaag tacgatggat
    20221 atgacaccga tcaatgtcac cacggcaatc agccatggaa tcaggtaaat gatgaacatg
    20281 aactcatccc tttgttatga ctcattcatt ccggcacatg agacttcata tatacaccct
    20341 ttttataaac ggacttaatg gtaaagtgta cacccagctt gcgattcgtc cgatagatga
    20401 gcgagttaat ctcgtcgatc cctaccgctt cactctccag catgctccgc tctggccaca
    20461 cctgagccac aatctgttcc cttgtcacaa agtggtcaag ttcgctatac agcagcttga
    20521 acagctgata ttccttcttg gacagcggaa tctccacttc accaatctgc acggtctgca
    20581 aatgatcctg caagcgtaca ccctcaccca gcagatccga cacacgatac tccctcgtct
    20641 ctccaagatc cccttcagcg cgaagctgaa tcaagccgtt gacgagcgtc aggctgtctc
    20701 cttcgccaaa cggatatttc tcatagggaa cgaggcgctg cccgttcagt tcggttccat
    20761 ttttgctatc cagatcctca atccataact gttgctgtac atcataatga atgcggcaat
    20821 gccgcttcga tatcatctga ttataaacag acaagtccaa ttcactaccg cctgtgtaac
    20881 gtcccaccgt aatggagcga ccctggctta cataagcgaa cgagccgtca ctttcctgcc
    20941 ctggcgtacg aatgacgatt tttgccgtct cccgcatgtt attctcccac cttcaacgat
    21001 cactcgatct ctatatacat ctcgtaaaca ataatgataa gatcatcaga tttgttccat
    21061 tgtttgcacc gctatagttc aatatagtgg tatacaggaa cgatttatat ttgttctact
    21121 cactctacta taccagacgt tgtgcttttt ttctcatgac ggccggatac ccactttagc
    21181 tcattcaaca agagaggtac ctttccatga acaaaaaaaa cattttcata tacgtattgc
    21241 tcgcctttgc cctgtccatg acattaaccg tgctctcccg tatgaacgat gatggcggag
    21301 aatcactgaa aggcacatca gctgccgaaa cctcgtggtt acaaatgaag atccagccct
    21361 agtctactct attataacgt gatctccgcg caaaacgttt cacgaatgtc ataataagct
    21421 atggcatcga atccaaatta aaacaattca ataaggcccc agattgctgg tcacagcagc
    21481 ccggagcctt attttggatt gtaaaacaat accgaaagta tagatgattg catgacttca
    21541 atcataaact gcccggcacg cagatggatt tcagccattt gtgctagtga cattttttag
    21601 ttttgtgatt ttggtttcct ctccaccttt caacccaaca atttctccat ttaatcacgg
    21661 tattaagggg tagagtatag acacttgcaa gtagatttct gttaggtgct tttcgattat
    21721 cgaggaacga cttttctgga ggattatata acataaattt aactcaaatt ataaataatg
    21781 ttaatcatat gtcattcatg gtttcatttt ctttgatata ctttctgcta ggtctatgaa
    21841 aggagatcat aggtgaaaaa agagattggt gtattgatgt tgtcatgtat cgtttttctt
    21901 tcaggatgtg gtggatcagg taatcccgca tcggttatgc aaggttcggg tgagtccccg
    21961 agtaaacaag taacaacaca gcaaaataat gagtattgtt ctctagaacg tacaagtttg
    22021 gatagtgaaa ctgaaaaata tttctatgga acttggaacg ttgagaagct tttaggattt
    22081 gcaaattcat ataatgatgc ctcagaatat ccaacaggtc aaaaatttat tggtgatgaa
    22141 ataatcatca aaaaagactt attttcatca aaaggaatta aaaactacag tagatatcaa
    22201 actgaactaa gaaacccatt atatgagttt acagcgacct gcaataattc agattctttt
    22261 tatagattat ataaattaga tattccaaac ttaaataaaa atgatgtcgt aaaagcaata
    22321 ggtgtaagta atccttctac aaaaattagt atacctgtaa gtttaagttt ttttgttgtt
    22381 aataacgaga agcttatctt gttatcagag gcaactatct ttgagcttaa gaaaatctcg
    22441 gataaaataa attaaggtta tgtgattagt ttcgtgctaa tttccaggag agattcccta
    22501 taattgattc tgaaaattcc tgtgaatata attttcaaac cagaaagggc cttggacagc
    22561 tccagttttt t
//
