LOCUS       NZ_CP043761            20873 bp    DNA     circular CON 27-OCT-2023
DEFINITION  Paenibacillus sp. 37 chromosome, complete genome.
ACCESSION   NZ_CP043761
VERSION     NZ_CP043761.1
KEYWORDS    RefSeq.
SOURCE      Paenibacillus sp. 37
  ORGANISM  Paenibacillus sp. 37
            Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae;
            Paenibacillus.
REFERENCE   1  (bases 1 to 7075616)
  AUTHORS   Nielsen,T.K., Hennessy,R.C. and Garcia,A.M.
  TITLE     Complete genome sequence of Paenibacillus sp. strain 37
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 7075616)
  AUTHORS   Nielsen,T.K., Hennessy,R.C. and Garcia,A.M.
  TITLE     Direct Submission
  JOURNAL   Submitted (06-SEP-2019) Plant and Environmental Sciences, University
            of Copenhagen, Thorvaldsensvej 40, Frederiksberg 1871, Denmark
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: Unicycler v. 0.4.8-beta
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 137.0x
            Sequencing Technology             :: BGISEQ500; PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Date                   :: 10/27/2023 04:50:44
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.6
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,538
            CDSs (total)                      :: 6,389
            Genes (coding)                    :: 6,340
            CDSs (with protein)               :: 6,340
            Genes (RNA)                       :: 149
            rRNAs                             :: 13, 13, 13 (5S, 16S, 23S)
            complete rRNAs                    :: 13, 13, 13 (5S, 16S, 23S)
            tRNAs                             :: 106
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 49
            CDSs (without protein)            :: 49
            Pseudo Genes (ambiguous residues) :: 0 of 49
            Pseudo Genes (frameshifted)       :: 25 of 49
            Pseudo Genes (incomplete)         :: 30 of 49
            Pseudo Genes (internal stop)      :: 11 of 49
            Pseudo Genes (multiple problems)  :: 14 of 49
            CRISPR Arrays                     :: 6
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 17:46:17
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 6402149
            Orig. end                         :: 6423022
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP043761.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..20873
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="16"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..20873
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..20873
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:10873](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..10873)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    321..335
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 18.82"
                     /tool="antismash"
     gene            complement(1495..2595)
                     /gene="ychF"
                     /locus_tag="F0220_RS27495"
     CDS             complement(1495..2595)
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /codon_start=1
                     /gene="ychF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005544868.1"
                     /locus_tag="F0220_RS27495"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="redox-regulated ATPase YchF"
                     /protein_id="WP_017691917.1"
                     /transl_table=11
                     /translation="MALKAGIVGLPNVGKSTLFNAITQAGAESANYPFCTIDPNVGIVE
                     VPDERLDKLTELVVPKKTVPTAFEFVDIAGLVRGASKGEGLGNKFLAHIREVDAIVHVV
                     RCFVDENITHVDGKIDPVSDIQTINLELILADIESVEKKIDRSKKNMKGGNKTASQEVE
                     VLERVKAVLYDDKPARSMELTDDELLIVRDLHLLTLKPVLYAANVAEDEIGDVANNAYV
                     QKVREFAAAENAEVVPISAKVEEEISELEGEDKQMFLEELGIEDSGLNLLIKAAYKLLG
                     LYTYFTAGVQEVRAWTIRKGTKAPGAAGVIHTDFERGFIRAEVVSYDDLVAAGSMNGAK
                     ERGQLRLEGKEYVVNDGDVMHFRFNV"
     gene            complement(2717..3172)
                     /locus_tag="F0220_RS27500"
     CDS             complement(2717..3172)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691916.1"
                     /locus_tag="F0220_RS27500"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_091013279.1"
                     /transl_table=11
                     /translation="MNQEDYASFRIRSIKDFAQEKVEAGTWAEEEAQQLAEESYERYLP
                     EGLNTPGAYLYNLMHPVDGNVGYIWFNITDNRRGKDAFLLDIVVEEAHRGKGYGTETME
                     ALEQTALSLGVDRIGLHVFGHNVRASSLYRKMGYEVTDLTMYKEIKG"
     misc_feature    3277..3294
                     /note="TFBS match to HipB, Bacterial antitoxin HipB,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     misc_feature    3429..3444
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: medium, score: 24.51"
                     /tool="antismash"
     gene            3445..3837
                     /locus_tag="F0220_RS27505"
     CDS             3445..3837
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0220_RS27505"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_091012932.1"
                     /transl_table=11
                     /translation="MSVIILGIAIVAFMSFLNAIDPFRHLRITIHNQSDYDLTNIQASL
                     VQGDNSLNNNENGSTYVVDKDISSGAKMKFAPQLKLSGEGAVSLAFTDSRGKTYNKTVC
                     GYTEYLSGNSYVTVTNENVTVKDECM"
     misc_feature    3866..3882
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 23.56"
                     /tool="antismash"
     gene            3908..4360
                     /locus_tag="F0220_RS27510"
     CDS             3908..4360
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="F0220_RS27510"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_091012930.1"
                     /transl_table=11
                     /translation="MLFNIILGASVALSILLSAHPASAVDVEDRVQDALTTSPITMENT
                     EDSIINPMDVQLIRPFNYSSYNAYEKSFTLVPDNGEDADVWIQNNSTDTIYAKITVGNL
                     SPIDIPIKKGTQKTTRIGVIGTTNVKVYIYSSTDHKMDMIIRAQQF"
     misc_feature    3934..3954
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 25.95"
                     /tool="antismash"
     gene            complement(4510..5577)
                     /gene="fni"
                     /locus_tag="F0220_RS27515"
     CDS             complement(4510..5577)
                     /EC_number="5.3.3.2"
                     /GO_function="GO:0004452 - isopentenyl-diphosphate
                     delta-isomerase activity [Evidence IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="fni"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691913.1"
                     /locus_tag="F0220_RS27515"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="WP_105600143.1"
                     /transl_table=11
                     /translation="MNEQERAGERLLPEVATGERKLEHVRLCLEENVAGEGVTSGMERY
                     AFRHHPLPELDFEEVHLETSFIGQKVRTPLLISSMTGGSKTTGAINERLARVANARGWA
                     LGVGSIRAAVEQPELASTFDVRRWAPDIPVIANLGAVQLNYGFTTADFQRAVDIAGADM
                     LVLHLNTLQEVFQPEGNTNFSGLFQRIENLCRELDVPVGVKEVGFGIDGVTAQRLYEAG
                     VAFIDVAGAGGTSWVQVEKYRNNNPVRRAAAEAFADWGIPTAECIQEVRGLNPAGALIG
                     SGGLYTGVDAAKALALGADLAGFGRSLLESAVASDDALNERLEQVEFELRTVMFGIGSG
                     RIEDLKQTSRLVERR"
     gene            complement(5864..7345)
                     /gene="crtI"
                     /locus_tag="F0220_RS27520"
     CDS             complement(5864..7345)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pyr_redox_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691912.1"
                     /locus_tag="F0220_RS27520"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_105600649.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1.5e-06, bitscore:
                     26.1, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 5.6e-07, bitscore: 27.9,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRGNVTIIGAGFGGLSCAIRLASKGVQVTILERQDHVGGKLQQIE
                     RDGYHFDRGPSTITMPSTFRSVFDHAGVAMEEYVQLYELEPRTRNIFADGTVVDLSGNR
                     GWMKEQIAAYSPEDAGRYDAFMDESAALYAEANRHFLGKLLLSPSDKYNLQMLRSLLRV
                     RPTVKLDKLLRSYFQHPHTLAMFGRYATYVGSSPYQSPSIFAMMGHVEAEVGIYGVKGG
                     TYQLIEGMTRLALEKGVQIITGIEVRQIVVRNGKVAGVDTDQGFREADQVVANGDVLSV
                     NRLLLAPEHRKEMSDARIRKYEPSISGFVTLAGVRKQYDALLHHTVFFPERYEPEFDHI
                     FRDRKMPEDPTIYICYSGYSEAGMAPAGASNLFILVNAPYLSDSWNWEEQTERYGAFVL
                     EQLAARGITGLNESDVLIRYTPRDIERDTLAHQGSIYGISSNSVKQTFMRPGNRSKDVQ
                     GLWYVGGTTHPGGGTPIVTLSGQLVGERLASEILR"
     gene            complement(7354..8502)
                     /locus_tag="F0220_RS27525"
     CDS             complement(7354..8502)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691911.1"
                     /locus_tag="F0220_RS27525"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_105600144.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.9e-22,
                     bitscore: 77.4, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNASEIFWIVLTSILGIQLLFALWNVSCLPKVRSFRSDKIQPPDL
                     MVSVLIPARNERLHIEGCLESVLASDTSGFRMEVLVLDDRSEDETAAMVQAIADHDARV
                     RLLHGVDLPEGWMGKSHACHRLVQEAKGEWYMFVDADVRLEPGAIRQTLAAGCEQSGGL
                     VTGFPYQVTKTWMEKLVVPMMVFTIISHLPIFMIRRSSSPMFVAATGAFLLIHRSSYEA
                     SGGHAAIQAHLVDDMSLAKAVKRAGHPVMLTDVHDVTNTRMYQNGVEVWNGYKKNMYEG
                     MGRKDVLLLGTMLMYTLMYIVPPMGLIIGLISGSSTPILYGVLGTLLGMAVKRVADHAG
                     GQPWWLALLQPVSMACVIAIGLASWQAGRSGKGYVWKGRRYN"
     gene            complement(8504..9265)
                     /locus_tag="F0220_RS27530"
     CDS             complement(8504..9265)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1141: acyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691910.1"
                     /locus_tag="F0220_RS27530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="lysophospholipid acyltransferase family protein"
                     /protein_id="WP_105600146.1"
                     /transl_table=11
                     /translation="MIRAVKSKPFNRIFALYNHYYLLRRRFRSFTLTGSLDPQVDIRDN
                     SPIDPTRPVIYFMNHSSWWDGLLLYHAARQTSRGDHYVMMEEQQLQQYAFFRKLGAYSI
                     NKESASGIRASLQYTSELLDSGKRVWIFPQGEILHQEARPIRFRPGIGLLLRRSPNAIA
                     VPVTLCHGMVQHDLPEISMQAGPPVMEDWKTLKSEEIASRLGLVLEQQLDDHRSELIRM
                     GQGSLPDALPLIRHVRSTSEKYDATRKRVNR"
     gene            complement(9234..10001)
                     /locus_tag="F0220_RS27535"
     CDS             complement(9234..10001)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691909.1"
                     /locus_tag="F0220_RS27535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="carotenoid biosynthesis protein"
                     /protein_id="WP_091012919.1"
                     /transl_table=11
                     /translation="MIQWLYWAWYVIGATLMLTIGVPDVLSFSNGLFLIFYALYVLDLI
                     YQGRNRTGLSDQSVIWLKPGLWIASVIIWLGGMGVEWVGVHTHWPFGEYAYSDFFGIHL
                     FSVPVTLGFAWIAVVGNSALLSGGGSTWTGKLLRAVKTGFWAVVLDLVLDPVAHARGFW
                     EWQAPGGFYGVPWTNYISWFIMGAFLSLFLPAMPGDRSSLLRAKWLYQLFILLFGLLAL
                     KEGITGSFIIAIAGVLLAEGSWLYDSRRKIKTV"
     gene            complement(10001..10873)
                     /locus_tag="F0220_RS27540"
     CDS             complement(10001..10873)
                     /EC_number="2.5.1.-"
                     /GO_function="GO:0004659 - prenyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691908.1"
                     /locus_tag="F0220_RS27540"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene/squalene synthase family protein"
                     /protein_id="WP_105600147.1"
                     /sec_met_domain="phytoene_synt (E-value: 6e-48, bitscore:
                     161.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 1.2e-68,
                     bitscore: 230.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEAILSRCEELMQKGSSSFYQAFRGLPSPRREAVYVIYAFCRMI
                     DDSVDEPEHSPYTIHEIHDLFGQLDDAEGHFIWPALRWLFSSFPHLDKGPFFRQMEGQL
                     TDLKVTHYTTMKELEHYCYLVAGTVGEMLLPVLRDDNGAEVAVNGIALGKGMQIVNIIR
                     DVGEDRARVRRYVPLEIMEKHGYTEQDFEDGIVDERFIAIVHELKAAALNWFRIGMDRL
                     DTYPTESAFSIELAAAFYSTILHAVERNDYDVYTKRAYVSDELKLEMLGAIVKRYPMLA
                     YQASRTAVS"
     gene            complement(10870..12333)
                     /gene="crtI"
                     /locus_tag="F0220_RS27545"
     CDS             complement(10870..12333)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691907.1"
                     /locus_tag="F0220_RS27545"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_105600149.1"
                     /transl_table=11
                     /translation="MKRAAIVGAGIGGLTSALLLNRQGWDVTVYERGSRVGGRIGYEQE
                     GEYRIDQGPTIVLLPEMLLGIMEEAGVDRSKIELLRCDPLYRVHYHSGRVMTKMTSREE
                     QTAEIERLFPGESRGFTRFMKDMDTLFPAGRAAFLERAFPRKRDFFTPSLMSLMGRLRA
                     HKSVRKAVGDYFEHEELLDAYSLQSLYIGGSPFGTPGIYSLLPYAEHEYGIWMVKGGYA
                     ALPAILEQELISRGGRVVLNAEVTGLTIKNGVCEGIETVAGAENVDAVIYNGDFPHLSG
                     LLGQAPEVARKRKPYRPSSGCVLLYVGVDKTWEDATTHQFFLPPSLEGSLQEVFNQRRI
                     PAKSSFYVFNPVALDETAAPSGQSVLYFLIPVPDAEGVDWDQESEALAERVLEEAEQRG
                     FPGLRAAIRWKKVRTPADAERDGLYGGGSFGIAPVLFQSGVYRPQPKPFPNIKGLYAAG
                     ASVHPGGGVPIVMQSARMAVNQLTKEMGT"
     gene            complement(12330..13880)
                     /gene="crtI"
                     /locus_tag="F0220_RS27550"
     CDS             complement(12330..13880)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016166 - phytoene dehydrogenase activity
                     [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="crtI"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691906.1"
                     /locus_tag="F0220_RS27550"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phytoene desaturase family protein"
                     /protein_id="WP_091012914.1"
                     /transl_table=11
                     /translation="MIPNQQRKRAAVIGAGPGGLAAAMLLSGQGYEVDVYEKQPVIGGR
                     SARLELGEYRFDRGATFLMMPQLIEEMFDVVGRKLSDYVHMKELTPLYALNFGDTVFTP
                     SRNREDTAAQIKELFPGNEDNYLRFMQEEEVKFGKVMPLLRRPFGKLTDYLRKDAVTAL
                     PKLDVHNTVYGILSRYFTDERLRWAFTFQSKYLGMSAWDCPGTFTILSFIEHHYGLFHP
                     IGGVNRIFQAMADVVEEYGGRIHTSTPVKQVIVRNGRAEGVLLENGERIDADHVVVNAD
                     FAHAVNHLFEPGVLKKYTPEKMKRKKYSCSTAMLYLGVDGGVDLPHHSIYFPEDYRLNV
                     DEITKHKMLSADPSLYIHNPSRLDSTLAPEGKSALYVLMPTPNLTADIDWEAERENVQE
                     AMMKRMEGIPELADIRSRIEECMLFTPLDWETELDVYRGATFNMAHNLGQMMYLRPHNQ
                     FEELKSVWLVGGGTHPGSGLPTIFESARISVRLIQEEDARTSSKPSSYVKTAEAGGHS"
     misc_feature    complement(14026..14041)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: medium, score: 22.33"
                     /tool="antismash"
     gene            complement(14147..15091)
                     /locus_tag="F0220_RS27555"
     CDS             complement(14147..15091)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691905.1"
                     /locus_tag="F0220_RS27555"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="cobalamin B12-binding domain-containing protein"
                     /protein_id="WP_105600151.1"
                     /transl_table=11
                     /translation="MYSIKQVAAMLGIPTVTLRAWENRYSAVTPERTESGYRMYTEENV
                     SDLRWLKEQVELHQTNISEAVRMLKVNKLNPPEAVPTPIMAPVPTMEEAYARMADQIYD
                     SLYNFQGERANGLIDFGFTMYGYDSMFYHVLVPILVRVGDAWEQGRASVAQEHFMTQLI
                     SQRFYQFFHLFPIYPHLPKVLALCPEGEHHQVGLLLFSLFMRKNGAEVLYLGANTPEEG
                     IFPIIREQKIKLVCLSITSPGLLERCDQLIERIKNEFPHIRFVLGGKGYERAEHARYPE
                     WIMPEDSSDWQSWIEREYLANRPPGARFGQVNN"
     misc_feature    complement(15232..15244)
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 20.88"
                     /tool="antismash"
     gene            15358..16833
                     /locus_tag="F0220_RS27560"
     CDS             15358..16833
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691904.1"
                     /locus_tag="F0220_RS27560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="phospholipase D family protein"
                     /protein_id="WP_105600152.1"
                     /transl_table=11
                     /translation="MVSLRRHTSDRKSSRGKFPYIRTGLVLLVLWLIAVMLYQTYKPLP
                     TGISYESPEYRVDQVEFLHDLTYPSSDGQMQHEQQIFQRMMQIVEEAEQFVLVDMFLFN
                     NYQHKGQNFPPVSTEFTEALVAKKNQHPDMDIWFITDEVNTNYNSAPNPLLEQMKQAGI
                     HVVITDVDPLRDSTPVYSAVWRTFFQWFGQSGDGWIKNLMATDGPDVTVRSYLKLLNVK
                     ANHRKVVVSEKTAIVSSGNIHDASAYHSNIAFEVTGPIIGDILQSEQAVLDISGGGQVP
                     TYTDPSTDSNTGDLRIRYLTEGKVNDAVLHEINQAGKGDTLWMGMFYVASPKVLEALLE
                     AAKRGTEIRLVLDPNENAFGQEKIGIPNRPVAAELHDKSDGKIQIRWYNTTKEQYHTKM
                     IYLAKATGDHIVLGGSTNFTPRNLNDYNLENDLWIAAPPDNKFTLDIANYFERIWNNND
                     AEFTLDLDEFQEKTTFLKGILYKLQLILGFTTF"
     gene            16960..17583
                     /locus_tag="F0220_RS27565"
     CDS             16960..17583
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017691903.1"
                     /locus_tag="F0220_RS27565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_091012907.1"
                     /transl_table=11
                     /translation="MTAQSIRDAALFHFARDGYEGASLRAIADEVGIKKPSIYAHFSCK
                     DDLFLHTLSFAFHEVTRHTLEYFRDHEDLPLEQRLKGLLIWFEQEYNAHASARLMLRNC
                     FYPPLSLYGEVMDQVYPFIDGMERALTRLLQRAMRHGDIPPIPAEQAAIAFMTFLDGIT
                     VEIIYGSSRRYKRRLEASWPVFWHGIHHLNEEAQSVVPEGDLTT"
     gene            17580..17921
                     /locus_tag="F0220_RS27570"
     CDS             17580..17921
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017811001.1"
                     /locus_tag="F0220_RS27570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_017691902.1"
                     /transl_table=11
                     /translation="MNRNWLYVFIGGIIEIVWVSGLKHASNAWEWTLTGIAIVISFGLI
                     IAASKRLPVGTVYAVFTGIGTAGTVLTEMVLFGEPFRLAKVLLIGLLLCGVIGLKLVTD
                     QQEAKGGAV"
     gene            17921..18235
                     /locus_tag="F0220_RS27575"
     CDS             17921..18235
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016822860.1"
                     /locus_tag="F0220_RS27575"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="multidrug efflux SMR transporter"
                     /protein_id="WP_091012904.1"
                     /transl_table=11
                     /translation="MAWMAIVGAGICEIFGVIGINGASTKKGWPYIVLMLVSFVFSFSL
                     LSYAMTSIPMGTAYAVWTGIGTVGSTLTGMFLFGERKEAKRLLFIAMILVAAVGLKLIT
                     "
     gene            18919..19866
                     /locus_tag="F0220_RS27580"
     CDS             18919..19866
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012655.3"
                     /locus_tag="F0220_RS27580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_091012901.1"
                     /transl_table=11
                     /translation="MNPIHEMNEKKKLIITTALKLFSSKGSAATSMQEIAELCGMSKGS
                     LYIMFKSKEELEASTLEYCMYTLMDEMTQIEHETSLSSRERLHKQIETLLIHVAEFKEF
                     LRVQLRSMMMDDEQQRKEQCHPQQRDLEIRTLHWFKDKLEEQYGREIEPYTIDLILLTH
                     GLFLSYVKIWFTEMPSLTVTKMATNLLQMMDYAAHGFLNQRPEPLIPLEEWPAWITEAQ
                     PDSTVMRHPIHIIKQMQDIAVSDLPAGQPKNDALETIAILRQEMMEFTPRRAIILGMMH
                     NLENVTAIQPLHSELQHILDAMYSRFIPADSSHT"
     misc_feature    20193..20206
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 20.67"
                     /tool="antismash"
ORIGIN
        1 attgtcaggc cgatccggtg atcagtcaca cggctttgtg ggaagttgta cgtacgaatc
       61 cgctcactgc ggtcacccgt tcccactttg ctcttccgct caacagagat cttcgcttcc
      121 tcttccatcc gtttcatatc gaagatacgc gtacgcagaa cctgcaacgc tttttccttg
      181 ttggagttct gtgattttcc atcctgacat gtcgcaacaa ttcccgttgg aacgtgcgtt
      241 acccgtactg cggatttcgt ggtattaacc gattgtccac cggcaccact ggaacagaac
      301 gtatccacac ggatgtcttt atcatgaatt tcgatatcaa aatcttcggc ttcaggcata
      361 accgcaaccg ttgaagttga tgtatgaata cgtccgccag actcagttgt tggaatacgc
      421 tgcacacggt gtgcgccgct ttcgtatttc attttgctgt atgcgccgcg tccgttgatc
      481 aggaaaacaa cctctttgaa tccaccgaga tcattcgtgt taacgtccat cagttctaca
      541 cgccagcctt gtgcatctgc ataacgcgtg tacatccgat aaagatctgc tgcaaacaat
      601 gctgcttcat ctccaccagc tgctccacga atctcaacaa taacgttctt gtcgtcattc
      661 ggatcttttg gtagcataag cacacgaatc aattcgtcta gctctttctg acgagtgctc
      721 agttcgtcta tttccatttt gaccatttcg cgcatctcat catccagttt ctcaccctgc
      781 atttcctttg cagcttcgag atcctgactt acctgtttgt attcattgta cgcttcataa
      841 gtcggttgca gatcggattg ttctttggag tattcccgca actttttgtt gtcacttgcc
      901 acatccgggt cacacaaaag ctcgctcaac ttgtcataac ggtcggctaa cgcctgtaat
      961 ttatccaaca tgtatagtca cctcacgcat tattttgtcc aagcacatca cattttcaat
     1021 aattatttca attcaatctt aattacatct ataatctata ttccacaacg cacaggattc
     1081 tcacgaatcc cctgaccgca gcatgtattc acattcatgt atgatcgacg tataacatcg
     1141 ctacaacgtc atcaaatcct ttacttttaa agttgatatc aagaaatcgt gtaccctgta
     1201 tgaaactcgc ttcaactcat ctgttacagc gcgaatttaa cgtggtatac gactcttaat
     1261 tatagcatat tcttatggtt ctgaatagta actgttcggc gcgcaataca aaaataattc
     1321 tatttacata tttcggattg tgtcttttcc ttttattata tccactacgc gcgatcaatc
     1381 cagtgcttgt acacaatata tagcgatcaa aaacataaaa agccctgtta tcttccaaag
     1441 aagataacag ggctgctata accatttttt aaaccatagt gaacggttta ggaattatac
     1501 gttgaaacgg aagtgcataa cgtcgccgtc atttacaacg tactctttac cttcaagacg
     1561 aagttgaccg cgctctttgg caccgttcat ggaacccgct gcaaccagat cgtcgtagga
     1621 aaccacctct gcacggatga atccacgctc gaagtcggtg tgaatgacac ctgctgcgcc
     1681 aggtgctttg gtacctttgc ggattgtcca agcacgaact tcctgtacac ctgctgtaaa
     1741 gtatgtgtac agaccgagca atttgtaagc tgctttgatc aacaggttga gaccggaatc
     1801 ctcgataccg agttcttcca ggaacatttg tttatcttcg ccttccagct cagagatctc
     1861 ttcttcaacc ttcgcactga ttggcaccac ttctgcgttc tcagcagctg cgaattctct
     1921 tactttttgc acgtaagcat tgttcgccac gtcgccgatt tcatcctcag ctacattggc
     1981 tgcgtacaga acaggcttca gggtaagcaa gtgcagatcg cgcacgatca gaagctcatc
     2041 atccgtaagt tccatgctgc gtgccggctt gtcatcgtac agaacagcct tcactctctc
     2101 caatacttct acttcttgag aggcagtctt gttgccgccc ttcatgtttt tcttggagcg
     2161 atcgattttc ttctcaacac tctcgatatc ggccaggatc agctccagat tgatcgtctg
     2221 gatgtcgctc accgggtcaa ttttgccatc gacgtgtgtg atgttctcat caacaaagca
     2281 acgtaccacg tgtacaattg catctacttc acgaatgtgg gcaaggaact tgttacccag
     2341 accttcacct ttgctcgcac cacgaacaag acccgcgata tctacaaact caaacgccgt
     2401 tggtactgtt ttcttaggta caacgagttc tgtcagtttg tccaaacgct catcgggtac
     2461 ttcaacgatc cccacgttag ggtcaattgt acagaacgga tagtttgccg attcggcacc
     2521 tgcttgtgta attgcgttaa acaatgtaga tttaccaacg ttaggcagac ctacgattcc
     2581 agctttcaaa gccatgtata tgacaactcc tcattgatta cttgttcggt atggataatc
     2641 ctatacatta tatatgacaa acctcaaggc atcaaggaac ttcgccaatt cgaccagagt
     2701 cccatccact attggtttac cctttgattt ccttatacat cgtcagatcc gttacctcat
     2761 atcccatctt gcgatacagg ctgctcgccc gcacattatg tccaaacaca tgcaggccaa
     2821 tgcgatccac gccaagactc aaggccgtct gttcaagcgc ctccatcgtc tctgttccat
     2881 accctttacc gcggtgtgct tcttcaacca caatgtctag caaaaatgca tctttgccac
     2941 gacgattatc cgtgatgtta aaccagatat accccacatt tccgtctaca ggatgcatca
     3001 gattgtagag atacgctccg ggtgtgttca agccttctgg cagataacgt tcataagatt
     3061 cctcggccag ttgctgcgcc tcttcctcag cccaggtgcc cgcttctact ttttcctgtg
     3121 caaagtcttt aatcgatcga atgcgaaaac tcgcataatc ttcctgattc attggagaaa
     3181 gtttcaactt tttcccctcc ttatttcaag tgatcttaat tatgtatgat ctctgtgcag
     3241 tcctttttgc actactagta tcttattgta tccttttctc ccattaagcg catgaagtta
     3301 ttctgaggat tcgaacttca gttttcatat ttatccattt aatttataac ttttgatctc
     3361 tacccattgt ttatacctca tgaaggaaag gagtggatca tactgaacac acgtcgccga
     3421 ttctccaaaa agaaaattat tatcttgtct gttatcatac tcggaatcgc catcgtcgct
     3481 tttatgagct ttctgaatgc aatcgatccc tttcgtcact taaggatcac aatccataat
     3541 cagtccgact atgacctcac caatattcaa gctagcctgg tccaaggcga caactcgtta
     3601 aacaacaatg agaatggctc cacctacgta gtcgataagg atatttccag cggagcaaag
     3661 atgaaattcg ccccacagct gaaactctct ggggaggggg ccgtatcctt ggcgtttacg
     3721 gacagccgcg gaaaaaccta taataaaacg gtctgcggtt atacggaata cttgtccggc
     3781 aattcctacg ttactgtaac caatgagaat gtcaccgtga aagatgaatg tatgtaataa
     3841 ttcgacaaaa cgattatgta agtaattgaa acattattac ataacaatga ataaggagga
     3901 aatcacattg ttattcaaca taattttagg tgcaagcgta gctttgtcca tattactttc
     3961 tgcacatcca gctagtgctg ttgatgtaga ggatagagtg caagatgccc ttactacttc
     4021 tccaatcact atggagaaca ctgaggattc gattatcaat ccaatggatg tacagcttat
     4081 cagaccattc aattacagca gttacaatgc gtacgaaaaa tcattcacat tggttcctga
     4141 caatggagaa gatgcagatg tttggattca aaacaatagt acggatacta tttatgccaa
     4201 aattaccgtg ggcaatcttt cccccattga catcccaatc aagaaaggga ctcaaaaaac
     4261 aacaagaata ggtgttatag gcacaacaaa cgtcaaagtt tatatctata gttcaacaga
     4321 tcataaaatg gatatgatta taagggccca acaattttaa tattataaat agtgtagagg
     4381 atacttctta agaagtatcc tctacactat ttatgttcca gattatctag caagcaatat
     4441 gagtagactc aaaatatata attaaataac tcctaatgaa gcttatatca ccatcatttc
     4501 aaccccggcc taccgccgtt ccaccagacg tgacgtctgc ttcaaatcct caatccgccc
     4561 tgagccaatg ccgaacatga cggtacgcaa ctcgaactcc acctgttcca accgctcatt
     4621 tagcgcatca tccgaagcga ccgcagattc aagcagagat cggccaaaac cagccagatc
     4681 cgcaccgaga gcgagggctt tggctgcatc cacgccagtg tacagtccac cgctgccaat
     4741 cagggccccc gctggattca gccctcgtac ttcctgaata cactccgctg tcggaatgcc
     4801 ccagtcggca aaagcttcag ctgctgcccg gcgtaccggg ttattgttgc ggtacttctc
     4861 tacctgtacc cagcttgtac cacctgcacc ggccacatca atgaatgcaa caccagcttc
     4921 atataagcgt tgggccgtca caccatcgat gccaaatcct acttctttta cgccaacagg
     4981 cacgtctaac tcacgacaca agttctcaat ccgctgaaat aatccgctga agttagtatt
     5041 accttccggc tggaaaactt cctgcaacgt gttcagatga agcacgagca tgtccgcacc
     5101 cgcaatatct acggcacgct ggaaatcagc cgtggtgaaa ccatagttca gctgcaccgc
     5161 gcccaggttg gcaatgaccg ggatgtccgg tgcccagcgc cgcacatcga aggtactcgc
     5221 cagttccggc tgttccacgg cagcccggat cgatcctacg ccgagcgccc agcctctggc
     5281 gttcgctact cgggcgaggc gctcattgat agcgcccgtt gttttgcttc cacccgtcat
     5341 cgaactgatg agcaagggtg tgcgtacttt ttggccaata aacgaagtct ccagatgcac
     5401 ctcttcaaaa tccagctccg gcagtgggtg atgacgaaaa gcataccgct ccataccgct
     5461 ggttacccct tctcctgcca cattctcctc aagacagagg cgcacgtgct ctagcttccg
     5521 ttctcccgta gccacttcgg gaagcagccg ttcgccggct cgctcttgtt cattcatgat
     5581 gagacctcct atgtgagaat cgtgcggatc gacaggataa cctgcctgtt cctagcttct
     5641 atgtatatac agctcaactc tatccagtat aacgttccaa accgcctatt gaaaggatgc
     5701 cccgacacca atgtctcagt taaatctcgg agcaccacta tcttatgcct actcaaaagc
     5761 acggatcatc tgtcgcacct tcaaagctgt tggttagcac gaacgacgta catgcacttg
     5821 gttcatcaga acacagctca ctccatcatc ctgcatatcg aacctatctc aagatttccg
     5881 atgccagtcg ttcaccgaca agctgcccgg acaatgtcac aatcggggtt ccgccgcctg
     5941 gatgtgttgt accgccgacg taccagagtc cttgtacatc tttgcttcgg ttgcccggcc
     6001 gcatgaaagt ctgcttcacg gagttggagg agatgccgta gatcgaccct tgatgcgcca
     6061 aagtatcccg ttcgatatct cgcggtgtgt accggatcaa cacatcggat tcatttaacc
     6121 cggtaattcc cctcgccgcc aactgttcca gcacaaacgc tccataacgt tccgtttgtt
     6181 cctcccaatt ccacgaatca gacaagtagg gggcattgac gagaatgaac agattgctgg
     6241 ctcccgccgg ggccatgcct gcttcggaat aaccggaata acagatatag atcgtaggat
     6301 cttctggcat tttacggtca cggaaaatat ggtcgaactc cggttcatac ctctccggga
     6361 aaaagacggt atggtgcagc agtgcatcgt attgctttcg cacacctgct aacgtcacaa
     6421 atcccgaaat ggatggttca tacttccgta tgcgggcatc actcatctct ttccgatgtt
     6481 ccggtgcgag cagtagtcga ttcacgctaa gcacatctcc attggcaacc acctgatcgg
     6541 cttcccggaa gccttgatcc gtatccacgc ctgccacttt gccattccga acaacaatct
     6601 gccggacctc aatgcccgta atgatctgta cgcctttttc cagtgccagt cgagtcatgc
     6661 cttcaatcag ttgataggtt ccgcctttga ccccgtagat gcccacctct gcttccacat
     6721 gacccatcat ggcaaagatc gaaggagact gatacggcga tgatcccaca taggtcgcgt
     6781 accgcccgaa catagcgagt gtatgcggat gctggaaata cgaacgcagc aacttatcca
     6841 gcttcaccgt tggccgcaca cgaagcaggc tgcgcagcat ctgaagattg tatttgtcag
     6901 aaggagacag caacaactta ccgagaaaat gacgattggc ttccgcatac agtgcggcag
     6961 actcatccat aaatgcatca tagcgacccg catcttccgg actgtacgcc gcgatctgct
     7021 ccttcatcca cccacgattg cctgacaaat cgaccactgt gccatctgca aatatattac
     7081 gcgtgcgcgg ctctaactca tatagctgta cgtattcttc catcgctaca cccgcatggt
     7141 caaagacgga acgaaaagtg gatggcatcg tgattgtgct cggtccccgg tcaaaatgat
     7201 acccgtcccg ctcaatctgt tgcagtttgc cacctacatg atcctgtcgt tccagaatgg
     7261 tcacctgcac accttttgaa gccaatcgga tcgcacatga cagacctccg aatcctgcac
     7321 cgataatcgt gacgttacct ctcatgtgac ccttcaatta taccgcctac ctttccatac
     7381 atacccctta ccggaccgac ctgcctgcca ggaagcaagt ccgatggcaa tgacacaggc
     7441 catgctgacc ggttgcagaa gggcaagcca ccagggctgt ccgccagcat gatccgctac
     7501 tcttttcaca gccataccta gtaatgttcc taacactcca tacagaatgg gcgtcgaact
     7561 acctgagatt aatcctataa tcaagcccat gggaggcaca atatacatca gcgtatacat
     7621 taacatcgtg ccaagcagca gtacgtcttt gcgccccata ccttcgtaca tgtttttctt
     7681 gtatccgttc catacttcaa caccgttctg atacatgcgg gtattcgtta catcatgcac
     7741 atcggtcagc atcaccggat gacctgcacg cttgactgct ttggcgagac tcatatcatc
     7801 caccagatgt gcctgaatgg cagcatgacc gccggatgct tcgtaactgg agcgatgaat
     7861 cagcaaaaaa gcccccgtag cggccacaaa catcggactg gatgatctgc gtatcatgaa
     7921 aatgggcaga tgactgatga tggtgaagac catcatcggt acgacaagct tttccatcca
     7981 cgtctttgtt acctgataag gaaaaccagt taccagacca ccgctctgct cacaccctgc
     8041 cgcaagtgtc tgccgaatgg cacctggctc tagacgcaca tctgcatcca caaacatata
     8101 ccattctccc ttggcctcct gaaccagcct gtgacacgca tgggatttcc ccatccagcc
     8161 ctcgggaaga tcgacaccat gcagtagacg cacacgtgca tcgtgatccg caatcgcttg
     8221 taccatggcc gctgtctcat cttcggagcg atcatccagc accagtactt ccatccggaa
     8281 tcccgatgta tcgctcgcga gcacactttc cagacatcct tcgatatgta gtctttcatt
     8341 tctggccgga atcagcaccg agaccatcag gtctgggggt tgtatcttgt ctgaccggaa
     8401 tgaacgtact ttgggcagac aggagacgtt ccatagagcg aacagcaact gtattcccaa
     8461 tatgcttgta agcacaatcc agaagatttc agatgcattc atcctaacgg ttcacccgct
     8521 ttcgcgtggc atcgtatttt tcacttgtcg aacgtacatg acgaatcagt ggcagcgcat
     8581 ctggcaagct cccctgtccc atccgtataa gttctgatct gtgatcgtct aactgctgtt
     8641 ccagcacaag accgagtctg gaggcaatct cttcactctt gagcgtcttc cagtcttcca
     8701 tcaccggagg gcctgcctgc atcgatattt ccggtagatc atgctgaacc attccatggc
     8761 acaaggttac cggtacggca atggcattcg gagagcgacg aagcaacaat ccgatgcctg
     8821 gacggaaccg aatcggtctg gcctcctgat ggagaatttc tccttgtgga aaaatccaga
     8881 cccttttccc cgaatccaat aattcactgg tgtactgtag agaggcccga ataccggacg
     8941 cactctcctt attgatcgaa tacgcaccca atttacgaaa aaaagcatat tgctggagct
     9001 gttgctcctc catcatcaca taatgatcac cccgcgatgt ctgcctggcc gcatgataga
     9061 gcagcagacc atcccaccag gagctgtggt tcatgaaata gatcaccgga cgagtcggat
     9121 caatcgggga gttgtccctg atgtccacct gcgggtccag tgaccccgtg agcgtgaagg
     9181 agcggaagcg ccgacgcagc agataataat gattatataa ggcaaaaatc cgattaaacg
     9241 gttttgattt tacggcgcga atcatacagc cagctccctt cggcaagaag cactcctgca
     9301 atggcgatga taaagctgcc tgtaattcct tccttcaggg cgagtaggcc gaatagaaga
     9361 ataaagagct gatacaacca ttttgcacgc agcaatgagc tacggtcacc aggcatggcc
     9421 ggaaggaaca gggacaggaa tgcgcccatg ataaaccagc ttatgtaatt ggtccacggg
     9481 accccgtaga atccacctgg agcctgccac tcccagaatc ctcttgcatg cgcgacagga
     9541 tcgagtacca gatcaagaac caccgcccag aacccggtct tcacggctcg aagcagtttt
     9601 ccagtccagg ttgaaccccc gccacttaac agcgccgagt tacccaccac tgcgatccag
     9661 gcgaaaccca gcgtaacagg cacactgaac agatgaatcc cgaaaaagtc agagtaagca
     9721 tactcaccaa agggccaatg cgtatgcacc cctacccact ccacgcccat accacccaac
     9781 cagatgatca cggaagcgat ccacagcccg ggtttcaacc agatgactga ctggtcggac
     9841 agacctgtcc gattgcgccc ctggtagatc agatccagca catacaatgc gtagaagatt
     9901 agaaataatc catttgaaaa ggacaacaca tccggcacgc cgatcgtcag catcaaggtt
     9961 gctccaatga cataccaagc ccagtaaagc cactggatca ttaggatacc gccgttcggg
    10021 aggcttgata ggccagcatc gggtaacgtt tcacaatcgc acccagcatc tccagtttca
    10081 attcatcgct aacatatgcc cgtttggtat atacgtcata gtcgttgcgt tcaaccgcgt
    10141 gtagaatggt ggagtaaaag gctgctgcca gctcgatgga aaacgcactt tccgttgggt
    10201 acgtatccag acgatccatg ccaatacgga accagttcaa tgctgccgct tttaattcat
    10261 gaacaatggc aataaagcgt tcgtccacga ttccgtcttc aaagtcctgt tcggtgtaac
    10321 catgcttctc catgatctcc agcggaacat accggcgcac tctggcccga tcttcaccaa
    10381 catcccgaat aatattaacg atctgcatcc ctttacccaa agcaatcccg ttcacggcta
    10441 cttctgcgcc gttatcatcc cgcaatacag gcaacaacat ctcgcctacg gttccggcca
    10501 ccagataaca ataatgctcc agttccttca tcgttgtata atgcgttact ttaagatccg
    10561 tgagctgccc ttccatctgg cggaagaatg gccccttatc cagatgagga aaactgctga
    10621 acaaccatct cagtgctggc cagataaaat gtccttccgc gtcgtccaac tgaccaaata
    10681 aatcatggat ttcgtgaatt gtatagggcg aatgctccgg ctcgtctaca ctgtcatcaa
    10741 tcatgcggca gaaggcataa atgacatata ccgcttcccg tcgtggactt ggcagccctc
    10801 taaaggcctg ataaaaagag gaagaaccct tttgcatcaa ctcttcacac ctgctcaaaa
    10861 tcgcttcatt catgttccca tctccttcgt gagttgattg acggccatac gtgcactctg
    10921 catcacaatc ggcactcccc ctccaggatg tacagatgct cctgcggcat ataacccctt
    10981 gatattaggg aatggtttgg gttgtggtcg gtatacaccg gactggaaca acactggcgc
    11041 aataccgaag cttccgcccc catagagccc gtctcgctct gcgtcagcgg gtgtacgcac
    11101 ctttttccac ctgatcgctg cacgaagtcc cgggaatcca cgttgctccg cttcttccaa
    11161 tacacgttct gccaatgctt cgctctcctg atcccagtcg acaccttcgg catcgggcac
    11221 gggaatgagg aaatacaata cactctgtcc tgaaggcgct gctgtctcat ccaatgcgac
    11281 cggattaaat acgtaaaatg aggactttgc cggaatgcgt cgctgattga agacttcctg
    11341 taaactacct tccagactcg gtggcaggaa gaactggtgc gtcgttgcat cttcccaagt
    11401 tttatccacg cccacataga gcaatacaca tccggaagag gggcgatatg gctttctttt
    11461 acgcgctacc tctggtgctt gaccaagcaa acccgaaaga tgggggaaat cgccattgta
    11521 gataactgca tccacatttt ctgcgcctgc taccgtttct ataccttcac atacaccgtt
    11581 tttaatcgtg agcccggtaa cttccgcatt cagcacaaca cgtccaccac gtgagatcag
    11641 ttcctgttcc agaatggccg gtaatgctgc atacccgccc ttcaccatcc agataccata
    11701 ttcatgctct gcgtaaggca aaagggaata gatacctggc gttccaaacg gtgatccacc
    11761 gatgtataga ctttgcagag agtatgcatc aagcaattcc tcatgctcaa aataatcgcc
    11821 taccgctttc cgaacacttt tgtgtgcacg caatctgccc atgagggaca tgagcgaagg
    11881 ggtgaagaaa tcccttttac gcggaaaagc cctttccaga aacgctgccc ggcctgccgg
    11941 aaacaacgtg tccatatctt tcatgaatcg tgtgaatccc cggctctctc ccgggaataa
    12001 acgttcaatc tccgccgtct gctcttcacg tgacgtcatc ttggtcatga cacgaccact
    12061 atggtaatgc actctgtata acggatcaca gcgaagcagt tcaatcttcg aacgatctac
    12121 gcctgcctcc tccatgatgc caagcaacat ctcaggcaat agcacaatcg tcggcccttg
    12181 atcgatccgg tattcccctt cctgctcata tccaatgcgt ccgccaacgc gagaaccccg
    12241 ttcatagaca gtgacatccc agccctgacg gttcaataac agtgcagaag taagtccacc
    12301 aatccctgcc cctacaatag cggcccgctt catgaatgcc ctccggcttc tgccgtcttc
    12361 acatacgagg atggtttgga gcttgtacgc gcgtcctctt cctgaatcag tctgacactg
    12421 atccgtgccg attcgaagat cgtgggcaat ccgctgcccg gatgtgttcc gccgcctacc
    12481 agccatacac ttttcaactc ttcaaactgg ttatggggac gcaggtacat catctgaccc
    12541 agattatgcg ccatgttaaa cgttgctccg cggtacacat ccagttcagt ctcccagtcg
    12601 agtggagtga acagcataca ttcttcgatc cggctgcgaa tatctgccag ctcaggaata
    12661 ccttccatgc gcttcatcat ggcctcttgc acattctccc gttctgcttc ccaatcgatg
    12721 tctgcggtaa gattaggcgt aggcatgaga acatataaag cggatttccc ttccggtgcc
    12781 agcgtcgaat cgagtctgga agggttatga atatatagag atggatcggc tgacaacatt
    12841 ttgtgctttg tgatctcatc aacgttcaac cggtagtcct cgggaaaata gatcgagtga
    12901 tgcggcagat ccactccacc atccacaccc agatacagca tcgctgtcga gcaggagtac
    12961 tttttgcgtt tcattttctc cggggtatat ttcttaagta cgcccggttc gaacagatgg
    13021 ttcaccgcat gtgcaaagtc agcgttcacc accacatggt ccgcgtcgat gcgttcaccg
    13081 ttctcaagca acacaccttc tgcacgacca ttgcgaacga tgacctgttt caccggggtg
    13141 gaagtatgta tgcgtcctcc gtattcttcc acgacatcag ccatggcttg gaagatccga
    13201 ttcacgccgc caatggggtg gaacaatccg tagtgatgct caatgaaaga tagtatggta
    13261 aaggtgcccg gacaatccca ggcagacata ccaagatatt tggattggaa tgtaaatgcc
    13321 cagcgtagac gctcatctgt aaaatagcgg gacaagatcc catagacggt gttgtggaca
    13381 tcaagcttag gtagagctgt taccgcgtct ttgcgtagat agtcagtcag cttgccaaac
    13441 ggacggcgca gcaaaggcat gactttgcca aacttcactt cctcttcttg catgaaccga
    13501 aggtaattgt cttcattgcc cggaaacaat tccttaatct gtgcagctgt atcttcccga
    13561 ttacgagaag gcgtgaacac cgtatcacca aagttcagtg cgtacagcgg ggttagttct
    13621 ttcatatgca cataatcgga taacttgcgt cccacgacgt cgaacatctc ttcaatcagc
    13681 tgaggcatca tcaaaaatgt tgccccccgg tcgaatcgat actcgcccag ttccaatctg
    13741 gcagaacgcc ccccgatgac cggctgtttc tcatacacat ctacttcgta cccctgaccg
    13801 gacaataaca tcgctgctgc aagtccaccc ggacccgcgc caatcacagc tgcacgtttg
    13861 cgttgttgat tcggtatcat gccactcacc tctctatgta gggaattcct atagttctct
    13921 agcccctagc ctattattaa accgcccaag aacactttaa gcggtaacca gcaaaaacat
    13981 tatacaaata taatacaaat attatacgac cttgtaaacc aaaaaatgac ccgtcggtca
    14041 aaatacgtgg atactccatt tataaacaca aaaaaacacc ccttgatcac tttcgtcaaa
    14101 ggatgtcctg tatacactaa cctattcata tcatttgaga ttatgtttag ttatttacct
    14161 gtccaaacct cgcaccaggt ggtcgatttg cgagatactc acgttctatc catgactgcc
    14221 aatccgatga atcctctggc ataatccatt ccgggtaacg agcatgttct gcacgctcat
    14281 agccctttcc accaagtaca aagcgaatat gtggaaactc gtttttaatt cgctctataa
    14341 gctgatcaca ccgttcaaga agccctggac ttgtgatcga aaggcagacc aacttgatct
    14401 tttgctcccg aataatcggg aagatgcctt cttctggcgt gttcgcaccg agatacagta
    14461 cttccgctcc atttttacgc ataaaaagag agaacagcag caatccaacc tgatggtgct
    14521 ccccttccgg acacaacgcc agaactttgg gcagatgcgg atagatcggg aacagatgga
    14581 aaaactgata aaaccgctgt gatatcagct gtgtcatgaa gtgttcctga gccaccgaag
    14641 ccctgccttg ctcccatgca tctccaaccc gaaccagtat gggcaccagc acatgataga
    14701 acatcgagtc gtacccgtac atggtgaaac caaaatcaat caaaccattg gcacgttcac
    14761 cctgaaagtt gtagagcgag tcatagatct gatctgccat gcgtgcgtag gcttcttcca
    14821 tcgtaggcac cggagccatg atcggcgtgg gcacagcctc gggcggattt aatttgttta
    14881 ctttcaacat ccgtaccgct tccgaaatat tggtctgatg tagctcaacc tgttctttca
    14941 gccagcgcag atccgaaaca ttctcttcgg tatacattcg ataacccgat tccgtccgct
    15001 caggggtgac cgcactatac cgattctccc aagcccggag cgtcaccgtc gggataccga
    15061 gcatggcagc gacttgtttg atggaataca ccttattacc cactttcttt cctaaatgtc
    15121 cagatttcac aggttatatc attggttccc cgtccttgtc aggcatatga aaaccctaac
    15181 attctacaaa aataatacac tcattataca caacgctcag acacctgtcg attgcataat
    15241 gccaattttg ccatatgcat tttaccgctg cattcgttat gctggcgggt tctcctgcgt
    15301 caacgttatc atccgtgtgg taatagaagt cagcaagtac agaaggggga gtccaccgtg
    15361 gtctcattac gccgccatac atcagaccgc aagtcttcac gcggcaaatt tccatacata
    15421 cgaacaggac tcgtcctatt ggtcctatgg ctcatcgccg tcatgctcta tcagacctac
    15481 aaaccattac caacgggcat ttcctacgaa agtccggagt atcgggtgga tcaagtcgag
    15541 ttcctgcatg acctcactta tccttcctcc gacggacaga tgcagcacga acagcagatt
    15601 ttccagcgca tgatgcaaat tgtggaggaa gcagagcaat ttgtcctggt ggatatgttc
    15661 ctgttcaata attatcagca taagggacag aactttcctc ccgtgagtac tgaattcacc
    15721 gaagcgctgg tcgccaaaaa aaatcagcat cctgatatgg acatctggtt tattactgat
    15781 gaagtaaata ccaactataa ctcagcacct aatccgttgc tggaacaaat gaaacaagca
    15841 ggcattcatg tggtcatcac ggatgtggac cctttgcgtg attcaactcc agtatactct
    15901 gcggtctggc ggaccttctt ccaatggttt gggcaatctg gagatggctg gatcaaaaac
    15961 ctgatggcca cggatggtcc ggatgtcact gtgcgttcct atctcaagct gctcaatgtg
    16021 aaggccaatc atcgcaaagt tgtggttagt gagaagacgg cgattgtctc ttctggcaat
    16081 atccatgatg cgagtgccta ccactcgaat attgcatttg aagtaacagg tccaatcatt
    16141 ggcgatattc ttcagtcaga gcaagctgta ctggatatct caggcggagg ccaggttcca
    16201 acctacacgg acccttccac ggattcaaac acgggagacc tacgaattcg ctatttaact
    16261 gaaggcaagg ttaatgacgc cgtactccat gagatcaatc aagctggcaa aggtgacacc
    16321 ttatggatgg gcatgttcta tgtggcctct ccgaaagtgt tggaagccct gctggaagcg
    16381 gcaaaacgag gaaccgagat ccggcttgta ctggatccaa atgaaaatgc ctttggtcag
    16441 gaaaagatcg gtattccgaa ccgccctgtc gctgctgaat tgcatgataa atccgacggt
    16501 aaaattcaga tccgctggta taacaccacc aaggagcaat accacaccaa gatgatctat
    16561 cttgccaaag caactggtga tcatattgtc ctcgggggtt caaccaactt cacacctcga
    16621 aacctgaatg actacaatct ggaaaatgat ttatggattg ctgctcctcc agacaataag
    16681 ttcacgcttg atatcgcgaa ttatttcgag cgtatttgga ataataatga tgccgaattc
    16741 acgttagacc tggatgagtt ccaggagaag actacgtttt tgaaaggtat cctatataag
    16801 ctgcaactga ttctgggttt tacaaccttt tgatcaaaaa ccacattcat acctgttata
    16861 tccgcctgta ctctactgtg caggcggata ttttcatctt gacaggggat gtgaagtgtg
    16921 aaaatataat tacctaacga ccgttaggaa ggtgatctga tgactgcaca atccattcgg
    16981 gatgcagccc tgttccattt tgccagagat ggctatgagg gggcttctct gagagctatt
    17041 gctgatgaag tcgggattaa aaaaccgtcc atatatgcac atttcagctg caaggatgac
    17101 ttgtttttac acacgctatc gtttgcattt cacgaagtaa cacggcacac actcgaatat
    17161 ttccgtgatc atgaggatct gccattggag cagaggctga agggtttact gatctggttc
    17221 gaacaagaat acaatgccca tgcgtcagcc cgcttgatgc tgcgcaattg tttctaccca
    17281 cccctttctc tgtatggcga agtgatggat caagtgtatc cgtttatcga tggtatggaa
    17341 cgtgcgctga ctcgtttgct gcaacgggca atgcgtcatg gagatattcc gcccattcct
    17401 gcggaacagg cagccattgc atttatgacg ttcctcgacg ggattaccgt ggagattatc
    17461 tatggaagtt cccgccggta caagagacgg ttggaagcat cctggcctgt cttttggcat
    17521 ggcattcatc atttgaacga agaggcacaa agcgttgtgc cggaaggaga tttaacaaca
    17581 tgaaccgcaa ctggttatat gtatttattg gtggaattat tgagattgtc tgggtaagcg
    17641 ggctgaaaca tgcctcgaat gcctgggagt ggactttgac ggggattgcc atcgtgatca
    17701 gctttggact gatcattgcc gcttccaaaa ggctgcctgt gggtacggtg tatgccgtct
    17761 ttacgggaat tggtacggcg ggcaccgtcc ttacggagat ggtactgttc ggtgagccgt
    17821 tccggttggc caaagtattg ctcatcgggc tgctgctctg cggcgtaatc ggactgaagc
    17881 tggttacgga tcagcaagaa gccaaaggag gtgcagtata atggcttgga tggcaattgt
    17941 aggtgcaggg atatgtgaaa ttttcggcgt aatcggtatt aatggtgctt ccaccaagaa
    18001 aggatggcca tatatcgtac tgatgctggt atcatttgtg ttcagcttct cgctgctgtc
    18061 ctacgccatg acgtccatcc cgatgggcac agcgtatgcc gtgtggacgg ggatcgggac
    18121 ggtcggcagt acgcttacag gcatgttcct gttcggtgaa cggaaagaag cgaagcgtct
    18181 cctgtttatc gcgatgattt tggtggcagc cgttggtctt aaactgatca cataatggaa
    18241 caactgaatt acactttata actccgattc cagtaccact ttctgatcgc tgttatcccc
    18301 agatttcttt gattcccttt gaagagggat aaatccggtg atagcatatg cttccgaaga
    18361 agctttctta cagaaagctt taaggcgacc acttcgtttc ttcaagtcgg ttctgcaatc
    18421 tccggtatcg tgtacttctt agcttccatt aggatatcta ttaaatttag taaaataaaa
    18481 aagacgactt cgatcaggaa gtcgtctttt ttgggatatg atataaatag ggaacctctt
    18541 tatactctgc cacgtaagaa aggatgttgt aatcatgaga aaattattgg cacgcatggg
    18601 ctcttataca gggtatgccc tgctgatcgg catggccatc ttctatctcc tcgcgctagt
    18661 cgccattatc atactcgcct tgtacgcctt cactggagga gcctaactta aacgttcttg
    18721 atagcaacac cctatcgtac atacaggcta cactttgtta catgttgttg tttttccctt
    18781 tgatcgtcct ctttcctcca tattagtttt ccaatttact cccatttgaa ttccttcaac
    18841 cagatcgttt atacttggtt tgaccttaaa gtcaattcaa gaactcacaa gttccctgat
    18901 gaggtgaatg catcgttaat gaaccctata catgagatga atgagaagaa aaagctcatc
    18961 attactacag cactcaagtt attctcatcc aaaggcagtg ctgcaacatc catgcaagag
    19021 attgccgaac tatgcgggat gtccaaaggc agcctttata tcatgttcaa atccaaagag
    19081 gaattagaag ccagtaccct ggagtactgc atgtacacac taatggacga gatgacgcag
    19141 attgagcatg aaaccagcct ctcctcgcga gaacgcctgc acaagcagat cgaaacactg
    19201 ctcattcatg tagccgaatt caaggaattt ttgcgggtac aattgcgaag catgatgatg
    19261 gatgatgaac agcaacgcaa ggaacagtgc catccacagc aaagagatct ggagatccgt
    19321 accttacatt ggtttaagga taagctggaa gagcagtatg gacgggagat tgaaccatat
    19381 acgattgatc ttattttgtt gacacacgga ctgttcctct cctatgtaaa aatctggttt
    19441 acagagatgc catctctcac cgttaccaaa atggcaacaa acttgctgca aatgatggac
    19501 tatgccgcac atggatttct taaccagcga cctgagcctt tgattcctct ggaggaatgg
    19561 cctgcctgga ttaccgaggc ccaacccgat tccacggtga tgcgacatcc aatccatatc
    19621 atcaaacaaa tgcaggatat cgccgtctcc gatttgcccg cagggcaacc gaagaatgat
    19681 gcacttgaaa ccattgccat tctcagacag gagatgatgg aattcacgcc gcggcgtgcc
    19741 attattctag gcatgatgca caatctggag aacgtaactg ccattcaacc cttgcattcc
    19801 gagcttcagc atattctgga tgccatgtat agccggttca tccctgctga ctcgtcacac
    19861 acataaacag gagaaacaga gaggagaaga aaccatcgta tgaaaggtat tattaatttt
    19921 tccctgaaca acaagtttgc gatctggatt ctgacgatta tcatctcttt cgcaggtttg
    19981 tacagcggat tgacgatgaa gcaagagacc attccgaaca tcaacgtacc gtttctgaat
    20041 gtcactgcca ttgatccggg ggctgcaccg gagggaattg ttgaggatgt cacgaagccg
    20101 ctggaagtaa aactacgtaa tgtagatggc gtgaagacgg tgacctccac ttccatggag
    20161 aatgcagcat cgatcacact cgaatttgat tatggaacag atctaaccaa cgcaacggca
    20221 accgttcgtg aggcactgaa tgaagttcaa ttgcctgaca gcgtgcagaa gccgaccatt
    20281 tccaagttca gcattaactc tttcccggtt gtatcgctga gcctgtctga caaggacggc
    20341 ggtgacctgg aacaattgac acgactggtt gaatcggata ttcagcctgc actcgaagat
    20401 attgacggtg tagctcaggt tcaggtttcc ggtcaatatg taaaagaagt tcaattgaag
    20461 tttgatcaag ccaaaatggc cgagctgggc ctaacggaag acacggtaaa cggcatcgtt
    20521 caaggttcat ccattcgtgt gcccctggga ctgttcgaac tggataaatc ccagaaagcc
    20581 gttgtcgtag atggcaacat cgtcgacatc gatgatctga aaaaccttgc cattccagtc
    20641 gtacccggcg gtgccggcgc ttctgcaggc aatggttcaa acgcagcccc acaaggctct
    20701 ggagcaccaa caggtgaagg ctcggcttct ggtgaagcag ctcaaggtac cgctcctgga
    20761 tctgcacagg gaacagaccc ggccgcaggc caagcagctg gcggtaatgc cagtgcaggt
    20821 agccctacag gtgctgccaa catgcctggt attccaactg taacactaag tga
//
