GCF_008042375.1 - 12 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

NZ_QNUC01000010.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	terpene-precursor	448,742	469,632

NZ_QNUC01000012.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 4.1	azole-containing-RiPP	71,922	95,428

NZ_QNUC01000013.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 5.1	NRPS,RRE-containing	1	11,609

NZ_QNUC01000019.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 11.1	RRE-containing	1	11,849	Low	thurincin H	ribosomal:RiPP

NZ_QNUC01000022.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 15.1	betalactone	9,068	34,306	Low	fengycin	NRPS:Type I

NZ_QNUC01000031.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 25.1	lanthipeptide-class-ii	10,192	38,094

NZ_QNUC01000033.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 27.1	RiPP-like	71,958	82,257

NZ_QNUC01000035.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 29.1	terpene	29,742	51,595	Low	molybdenum cofactor	other:other

NZ_QNUC01000004.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 34.1	RiPP-like	35,423	45,689

NZ_QNUC01000043.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 38.1	NRPS	1	48,241

NZ_QNUC01000007.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 61.1	t3nrps-iterative,NRP-metallophore,NRPS	43,733	98,530	High	bacillibactin	NRPS:Type I

NZ_QNUC01000008.1 (Bacillus sp. BF9-10)

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 68.1	NI-siderophore	160,257	191,963	High	petrobactin	other:other

Region	Type	From	To	Similarity Confidence	Most similar known cluster
Region 2.1	terpene-precursor	448,742	469,632
Region 4.1	azole-containing-RiPP	71,922	95,428
Region 5.1	NRPS,RRE-containing	1	11,609
Region 11.1	RRE-containing	1	11,849	Low	thurincin H	ribosomal:RiPP
Region 15.1	betalactone	9,068	34,306	Low	fengycin	NRPS:Type I
Region 25.1	lanthipeptide-class-ii	10,192	38,094
Region 27.1	RiPP-like	71,958	82,257
Region 29.1	terpene	29,742	51,595	Low	molybdenum cofactor	other:other
Region 34.1	RiPP-like	35,423	45,689
Region 38.1	NRPS	1	48,241
Region 61.1	t3nrps-iterative,NRP-metallophore,NRPS	43,733	98,530	High	bacillibactin	NRPS:Type I
Region 68.1	NI-siderophore	160,257	191,963	High	petrobactin	other:other

No secondary metabolite regions were found in these records:: NZ_QNUC01000001.1 (Bacillus sp. BF9-10); NZ_QNUC01000011.1 (Bacillus sp. BF9-10); NZ_QNUC01000014.1 (Bacillus sp. BF9-10); NZ_QNUC01000015.1 (Bacillus sp. BF9-10); NZ_QNUC01000016.1 (Bacillus sp. BF9-10); NZ_QNUC01000017.1 (Bacillus sp. BF9-10); NZ_QNUC01000018.1 (Bacillus sp. BF9-10); NZ_QNUC01000002.1 (Bacillus sp. BF9-10); NZ_QNUC01000020.1 (Bacillus sp. BF9-10); NZ_QNUC01000021.1 (Bacillus sp. BF9-10); NZ_QNUC01000023.1 (Bacillus sp. BF9-10); NZ_QNUC01000024.1 (Bacillus sp. BF9-10); NZ_QNUC01000025.1 (Bacillus sp. BF9-10); NZ_QNUC01000026.1 (Bacillus sp. BF9-10); NZ_QNUC01000027.1 (Bacillus sp. BF9-10); NZ_QNUC01000028.1 (Bacillus sp. BF9-10); NZ_QNUC01000029.1 (Bacillus sp. BF9-10); NZ_QNUC01000003.1 (Bacillus sp. BF9-10); NZ_QNUC01000030.1 (Bacillus sp. BF9-10); NZ_QNUC01000032.1 (Bacillus sp. BF9-10); NZ_QNUC01000034.1 (Bacillus sp. BF9-10); NZ_QNUC01000036.1 (Bacillus sp. BF9-10); NZ_QNUC01000037.1 (Bacillus sp. BF9-10); NZ_QNUC01000038.1 (Bacillus sp. BF9-10); NZ_QNUC01000039.1 (Bacillus sp. BF9-10); NZ_QNUC01000040.1 (Bacillus sp. BF9-10); NZ_QNUC01000041.1 (Bacillus sp. BF9-10); NZ_QNUC01000042.1 (Bacillus sp. BF9-10); NZ_QNUC01000044.1 (Bacillus sp. BF9-10); NZ_QNUC01000045.1 (Bacillus sp. BF9-10); NZ_QNUC01000046.1 (Bacillus sp. BF9-10); NZ_QNUC01000047.1 (Bacillus sp. BF9-10); NZ_QNUC01000048.1 (Bacillus sp. BF9-10); NZ_QNUC01000049.1 (Bacillus sp. BF9-10); NZ_QNUC01000005.1 (Bacillus sp. BF9-10); NZ_QNUC01000051.1 (Bacillus sp. BF9-10); NZ_QNUC01000052.1 (Bacillus sp. BF9-10); NZ_QNUC01000053.1 (Bacillus sp. BF9-10); NZ_QNUC01000054.1 (Bacillus sp. BF9-10); NZ_QNUC01000055.1 (Bacillus sp. BF9-10); NZ_QNUC01000056.1 (Bacillus sp. BF9-10); NZ_QNUC01000057.1 (Bacillus sp. BF9-10); NZ_QNUC01000058.1 (Bacillus sp. BF9-10); NZ_QNUC01000059.1 (Bacillus sp. BF9-10); NZ_QNUC01000006.1 (Bacillus sp. BF9-10); NZ_QNUC01000060.1 (Bacillus sp. BF9-10); NZ_QNUC01000061.1 (Bacillus sp. BF9-10); NZ_QNUC01000062.1 (Bacillus sp. BF9-10); NZ_QNUC01000063.1 (Bacillus sp. BF9-10); NZ_QNUC01000066.1 (Bacillus sp. BF9-10); NZ_QNUC01000070.1 (Bacillus sp. BF9-10); NZ_QNUC01000071.1 (Bacillus sp. BF9-10); NZ_QNUC01000074.1 (Bacillus sp. BF9-10); NZ_QNUC01000075.1 (Bacillus sp. BF9-10); NZ_QNUC01000076.1 (Bacillus sp. BF9-10); NZ_QNUC01000077.1 (Bacillus sp. BF9-10); NZ_QNUC01000009.1 (Bacillus sp. BF9-10)

Compact view

NZ_QNUC01000010.1 - Region 1 - terpene-precursor

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Location: 448,742 - 469,632 nt. (total: 20,891 nt) Show pHMM detection rules used

terpene-precursor: (PT_FPPS_like and not PT_HPP)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Terpene

TFBS Finder

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: carboxylase

DN396_RS10780: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Ligases: synthase synthetase

DN396_RS10745: 1-deoxy-D-xylulose-5-phosphate synthase

smcogs: SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase

DN396_RS10750: Polyprenyl synthetase

smcogs: SMCOG1182: Polyprenyl synthetase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002283.2	0.49	terpene	sodorifen	Serratia plymuthica
BGC0001361.3	0.49	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.39	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0002219.2	0.39	terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0000665.5	0.38	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0002284.3	0.38	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002283.2	0.49	terpene	sodorifen	Serratia plymuthica
BGC0001361.3	0.49	terpene	sodorifen	Serratia plymuthica 4Rx13
BGC0002397.2	0.47	terpene	astallatene	Arabidopsis thaliana
BGC0002400.2	0.44	terpene	boleracene	Brassica oleracea var. oleracea
BGC0002398.2	0.39	terpene	(-)-ent-quiannulatene	Arabidopsis thaliana
BGC0002219.2	0.39	terpene	(-)-(R)-nephthenol	Stereum hirsutum FP-91666 SS1
BGC0000665.5	0.38	other (other), terpene	xiamycin, indosespene, sespenine, dixiamycin A, dixiamycin B, sulfadixiamycin A, sulfadixiamycin B, sulfadixiamycin C	Streptomyces sp. HKI0576
BGC0002284.3	0.38	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0000639.3	0.38	terpene	carotenoid	Enterobacteriaceae bacterium DC260
BGC0000642.3	0.37	terpene	carotenoid	Enterobacteriaceae bacterium DC413

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
sesquiterpene precursor		FPP	C15	acyclic	PP

Genes with terpene domains:

DN396_RS10750: PT_FPPS_like

Domain 1 (32 - 295): Prenyltransferase; Farnesyl diphosphate synthase like

Subtype: Farnesyl diphosphate synthase, bacterial

Reactions:: IPP, DMAPP → FPP

Transcription Factor Binding Sites

Binding sites found:

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.49 out of 27.78

Confidence: medium

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 21.32 out of 25.88

Confidence: medium

ANR

Description: Anaerobic transcriptional regulator
Species: Pseudomonas putida KT2440
Score: 21.28 out of 26.33

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.30 out of 28.19

Confidence: medium

Additional weak hits (1):

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 25.40 out of 33.14

Confidence: weak

Terpene

TFBS Finder

Glossary

Acronym	Full name
DMAPP	Dimethylallyl diphosphate
FPP	Farnesyl diphosphate
IPP	Isopentenyl diphosphate
PP	Diphosphate

TFBS definitions

Regulator	Description
ANR	Anaerobic transcriptional regulator
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
PsrA	Oleic acid responsive regulator
ZuR variant 1	Zinc-responsive repressor

NZ_QNUC01000012.1 - Region 1 - azole-containing-RiPP

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Location: 71,922 - 95,428 nt. (total: 23,507 nt) Show pHMM detection rules used

azole-containing-RiPP: ((YcaO or TIGR03604) and (((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or (PF06968 or PF04055 or PF07366)) or (goadsporin_like or PF00881 or TIGR03605)) or TIGR03882 or TIGR03603 or thiostrepton or TIGR03602)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Azole RiPPs

Gene/CDS overview

Filter:

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: oxidoreductase

DN396_RS12750: pyridine nucleotide-disulfide oxidoreductase

smcogs: SMCOG1175: pyridine nucleotide-disulfide oxidoreductase

Transferases: methyltransferase

DN396_RS12735: methyltransferase

smcogs: SMCOG1089: methyltransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000607.5	0.43	ribosomal	micrococcin P1	Macrococcus caseolyticus
BGC0001535.3	0.43	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0001146.5	0.41	ribosomal	cyclothiazomycin C	Streptomyces sp. NRRL WC-3908
BGC0001173.5	0.41	ribosomal	plantazolicin	Bacillus pumilus ATCC 7061
BGC0000606.5	0.39	ribosomal	lactazole	Streptomyces lactacystinaeus
BGC0001860.4	0.38	ribosomal	thiomuracin	Thermobispora bispora DSM 43833
BGC0000628.4	0.38	ribosomal	lactocillin	Lactobacillus paragasseri JV-V03
BGC0000613.5	0.38	ribosomal	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001145.5	0.38	ribosomal	cyclothiazomycin b1	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001640.3	0.38	ribosomal	kocurin	Kocuria rosea

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000607.5	0.43	ribosomal	micrococcin P1	Macrococcus caseolyticus
BGC0001535.3	0.43	other (other)	branched-chain fatty acids	Streptomyces filamentosus
BGC0001146.5	0.41	ribosomal	cyclothiazomycin C	Streptomyces sp. NRRL WC-3908
BGC0001173.5	0.41	ribosomal	plantazolicin	Bacillus pumilus ATCC 7061
BGC0000606.5	0.39	ribosomal	lactazole	Streptomyces lactacystinaeus
BGC0001860.4	0.38	ribosomal	thiomuracin	Thermobispora bispora DSM 43833
BGC0000628.4	0.38	ribosomal	lactocillin	Lactobacillus paragasseri JV-V03
BGC0000613.5	0.38	ribosomal	thiomuracin A	Nonomuraea sp. Bp3714-39
BGC0001145.5	0.38	ribosomal	cyclothiazomycin b1	Streptomyces mobaraensis NBRC 13819 = DSM 40847
BGC0001640.3	0.38	ribosomal	kocurin	Kocuria rosea

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 24.43 out of 32.93

Confidence: medium

Additional weak hits (2):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.69 out of 39.62

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.85 out of 29.38

Confidence: weak

(Thi)azol(in)e containing peptide predictions

No core peptides found.

RREFinder

TFBS Finder

Azole RiPPs

RRE predictions

: RRE type: Heterocycloanthracin_C_RRE; Location: 0 - 100; Score: 181.3; RRE type: Thiopeptide_F_RRE; Location: 10 - 89; Score: 39.3

TFBS definitions

Regulator	Description
LexA variant 3	Repressor of DNA damage response

Core peptide predictions

No core peptides found.

NZ_QNUC01000013.1 - Region 1 - NRPS,RRE-containing

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Location: 1 - 11,609 nt. (total: 11,609 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)
RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Ligases: ligase

DN396_RS13060: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002164.2	0.71	NRPS	peramine	Epichloe festucae
BGC0001135.5	0.68	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001261.3	0.66	NRPS	AM-toxin	Alternaria alternata
BGC0001132.4	0.64	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.4	0.63	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.4	0.62	NRPS	AbT1	Aureobasidium pullulans
BGC0002135.2	0.62	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0002286.3	0.61	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001240.4	0.61	NRPS	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001641.4	0.60	NRPS	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002164.2	0.68	NRPS	peramine	Epichloe festucae
BGC0001135.5	0.67	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001261.3	0.66	NRPS	AM-toxin	Alternaria alternata
BGC0001132.4	0.66	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001128.4	0.65	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0000307.4	0.65	NRPS	AbT1	Aureobasidium pullulans
BGC0002135.2	0.64	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0002286.3	0.64	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001240.4	0.64	NRPS	serinocyclin A, serinocyclin B	Metarhizium robertsii
BGC0001641.4	0.64	NRPS	kolossin	Photorhabdus laumondii subsp. laumondii TTO1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.22 out of 23.79

Confidence: medium

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 24.91 out of 30.25

Confidence: medium

Additional weak hits (1):

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.27 out of 25.88

Confidence: weak

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

RREFinder

TFBS Finder

Predicted core structure(s)

For candidate cluster 1, location 0 - 11609:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (X - Pro)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

DN396_RS13060: X - Pro

Search NORINE for peptide: strict or relaxed

AMP-binding (18..408): X

nrpys: Gly, Ala, Val, Leu, Ile, Abu, Ival

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: FSSAFDASVFETLLTSAGSINAYGPTETTVYTVA
Nearest Stachelhaus code(s):: Phe DAFTVAAVCK (71% 8Å match); Leu or Ile DAFFNGAVYK (44% 8Å match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1069..1458): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: FASSFDVSLYDAFLISAGSINAYGPTEASVATIE
Nearest Stachelhaus code(s):: 4Me-Pro DVQFIAHVAK (50% 8Å match)
Stachelhaus code match:: 80% (moderate)

Link to PARAS substrate predictor

RRE predictions

: RRE type: Pantocin_Microcin_RRE; Location: 7 - 89; Score: 27.4

TFBS definitions

Regulator	Description
ColR	Phenol-responsive regulator
IolR	Regulator of the inositol catabolism

NZ_QNUC01000019.1 - Region 1 - RRE-containing

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Location: 1 - 11,849 nt. (total: 11,849 nt) Show pHMM detection rules used

Region on contig edge.

RRE-containing: minimum(1, [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE, Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE, Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE, Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE, Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE, Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE, Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE, Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE, Thiaglutamate_B_RRE, Thiaglutamate_G_RRE, Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE, Thurincin_rSAM_RRE, Trifolitoxin_RRE])

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: acetyltransferase

DN396_RS17115: GCN5-related N-acetyltransferase

smcogs: SMCOG1111: GCN5-related N-acetyltransferase

Lyases: cyclase

DN396_RS17080: diguanylate cyclase

smcogs: SMCOG1025: diguanylate cyclase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000600.3	0.53	ribosomal	thurincin H	Bacillus thuringiensis
BGC0002700.2	0.43	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002667.2	0.40	ribosomal	estericin A	Clostridium estertheticum
BGC0000616.4	0.40	ribosomal	amylocyclicin	Bacillus velezensis FZB42
BGC0002111.3	0.40	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0001887.3	0.40	ribosomal	huazacin	Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0001684.3	0.38	other (other)	N-acyloxyacyl glutamine	Klebsiella variicola
BGC0000523.3	0.36	ribosomal	lactocin S	Lactobacillus sakei
BGC0000561.5	0.36	ribosomal	thermophilin 1277	Streptococcus thermophilus

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000600.3	0.53	ribosomal	thurincin H	Bacillus thuringiensis
BGC0002700.2	0.43	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0000558.5	0.42	ribosomal	sublancin 168	Bacillus subtilis subsp. subtilis str. 168
BGC0002667.2	0.40	ribosomal	estericin A	Clostridium estertheticum
BGC0000616.4	0.40	ribosomal	amylocyclicin	Bacillus velezensis FZB42
BGC0002111.3	0.40	ribosomal	andalusicin A, andalusicin B	Bacillus thuringiensis serovar andalousiensis NRRL B-23139
BGC0001887.3	0.40	ribosomal	huazacin	Bacillus thuringiensis serovar huazhongensis BGSC 4BD1
BGC0001684.3	0.38	other (other)	N-acyloxyacyl glutamine	Klebsiella variicola
BGC0000523.3	0.36	ribosomal	lactocin S	Lactobacillus sakei
BGC0000561.5	0.36	ribosomal	thermophilin 1277	Streptococcus thermophilus

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.38 out of 28.19

Confidence: medium

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 25.27 out of 32.93

Confidence: medium

Additional weak hits (5):

BldD

Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 18.71 out of 23.43

Confidence: weak

DosR

Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 20.52 out of 29.51

Confidence: weak

DosR

Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 20.52 out of 29.51

Confidence: weak

LexA variant 1

Description: Repressor of DNA damage response
Species: Streptomyces coelicolor
Score: 21.27 out of 29.65

Confidence: weak

BldD

Description: Development and antibiotic global regulator
Species: Streptomyces coelicolor
Score: 18.71 out of 23.43

Confidence: weak

RREFinder

TFBS Finder

RRE predictions

: RRE type: Thurincin_rSAM_RRE; Location: 17 - 72; Score: 75.9

TFBS definitions

Regulator	Description
LexA variant 3	Repressor of DNA damage response
ZuR variant 1	Zinc-responsive repressor

NZ_QNUC01000022.1 - Region 1 - betalactone

Download region GenBank file

Download region SVG

Location: 9,068 - 34,306 nt. (total: 25,239 nt) Show pHMM detection rules used

betalactone: (HMGL-like and AMP-binding)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

DN396_RS18615: acyl-CoA dehydrogenase

smcogs: SMCOG1006: acyl-CoA dehydrogenase

Transferases: acetyltransferase carboxylase transferase

DN396_RS18570: GCN5-related N-acetyltransferase

smcogs: SMCOG1111: GCN5-related N-acetyltransferase

DN396_RS18590: acetyl-CoA carboxylase, carboxyl transferase,

smcogs: SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase,

DN396_RS18610: acetyl-CoA carboxylase biotin carboxylase

smcogs: SMCOG1090: acetyl-CoA carboxylase biotin carboxylase

Hydrolases: hydrolase

DN396_RS18655: metallo-beta-lactamase family protein

smcogs: SMCOG1170: metallo-beta-lactamase family protein

Lyases: hydratase

DN396_RS18595: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

Ligases: ligase synthase

DN396_RS18585: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

DN396_RS18600: 2-isopropylmalate synthase

smcogs: SMCOG1271: 2-isopropylmalate synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002284.3	0.55	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0000131.5	0.46	PKS	pyrrolomycin	Streptomyces sp. UC 11065
BGC0000706.3	0.46	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000234.5	0.44	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000623.3	0.42	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001103.5	0.42	NRPS, PKS	mycosubtilin	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001226.4	0.42	ribosomal	streptocollin	Streptomyces collinus Tu 365
BGC0000563.4	0.42	ribosomal	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0001095.5	0.41	NRPS	fengycin	Bacillus velezensis FZB42

Reference	Similarity score	Type	Compound(s)	Organism
BGC0002284.3	0.55	other (other)	corynecin III, corynecin I, corynecin II	Rhodococcus sp. H-CA8f
BGC0000131.5	0.46	PKS	pyrrolomycin	Streptomyces sp. UC 11065
BGC0000706.3	0.46	saccharide	kanamycin	Streptomyces kanamyceticus
BGC0000234.5	0.44	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0000623.3	0.42	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0001103.5	0.42	NRPS, PKS	mycosubtilin	Bacillus subtilis subsp. spizizenii ATCC 6633
BGC0001226.4	0.42	ribosomal	streptocollin	Streptomyces collinus Tu 365
BGC0000563.4	0.42	ribosomal	venezuelin	Streptomyces venezuelae ATCC 10712
BGC0002700.2	0.41	ribosomal	bacinapeptin	Bacillus nakamurai
BGC0001095.5	0.41	NRPS	fengycin	Bacillus velezensis FZB42

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

NtrC

Description: Nitrogen regulatory protein C
Species: Pseudomonas putida KT2440
Score: 24.10 out of 29.72

Confidence: medium

Additional weak hits (3):

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 22.23 out of 33.73

Confidence: weak

PsrA

Description: Oleic acid responsive regulator
Species: Pseudomonas sp.
Score: 20.06 out of 25.88

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 25.24 out of 33.14

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
NtrC	Nitrogen regulatory protein C

NZ_QNUC01000031.1 - Region 1 - lanthipeptide-class-ii

Download region GenBank file

Download region SVG

Location: 10,192 - 38,094 nt. (total: 27,903 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

Lanthipeptides

TFBS Finder

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: protease

DN396_RS23015: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

Lyases: cyclase

DN396_RS23020: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

DN396_RS23065: lanthionine synthetase C family protein

smcogs: SMCOG1070: lanthionine synthetase C family protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.5	0.72	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000623.3	0.60	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000517.4	0.57	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000552.3	0.56	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000554.4	0.56	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000497.3	0.54	ribosomal	BHT-Aα, BHT-Aβ	Streptococcus ratti
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0001555.4	0.52	ribosomal	colicin V	Escherichia coli chi7122
BGC0000504.5	0.52	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000590.5	0.51	ribosomal	microcin N	Escherichia coli

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000525.5	0.72	ribosomal	lichenicidin VK21 A1, lichenicidin VK21 A2	Bacillus licheniformis
BGC0000623.3	0.60	ribosomal	plantaricin W α, plantaricin W β	Lactobacillus plantarum
BGC0000517.4	0.57	ribosomal	haloduracin β, haloduracin α	Bacillus halodurans C-125
BGC0000552.3	0.56	ribosomal	SmbA, SmbB	Streptococcus mutans
BGC0000554.4	0.56	ribosomal	SRO15-3108	Streptomyces filamentosus NRRL 15998
BGC0000497.3	0.54	ribosomal	BHT-Aα, BHT-Aβ	Streptococcus ratti
BGC0001229.4	0.53	ribosomal	SBI-06990 A1, SBI-06989 A2	Streptomyces bingchenggensis BCW-1
BGC0001555.4	0.52	ribosomal	colicin V	Escherichia coli chi7122
BGC0000504.5	0.52	ribosomal	cytolysin ClyLl, cytolysin ClyLs	Plasmid pAD1
BGC0000590.5	0.51	ribosomal	microcin N	Escherichia coli

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Lanthipeptide predictions

Lanthipeptide(s) for DN396_RS23020

DN396_RS23025

Leader:

MSSSKKVVEAWKNPVERSKNEDAPNHPAGEVDSKEIQSLFGA

DN396_RS23030

Leader:

MSSSKKVVEAWKNPVERSKNEDAPNHPAGEVDSKEIQSLFGA

DN396_RS23035

Leader:

MSSSKKVVEAWKNPVERSKNEDAPNHPAGEVDSKEIQSLFGA

Shared core:

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

Core with dehydrations:

GEGDVDhbPEGLDhaDhaWLGNNGGYCysDhbLDhbKECysMPDhaCysN

antiSMASH-DB 4.0 matches for DN396_RS23025

100.0%

NZ_CP015591.1and 19 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27560_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29375_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29370_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29365_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: IGI01_RS29005_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29780_lanthipeptideNZ_NVJC01000007.1 Lanthipeptides: COM38_RS07400_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptide

Lanthipeptides: A7A70_RS27565_lanthipeptide

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

96.9%

NC_018499.1and 7 others:

NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptide

Lanthipeptides: BCK_RS27860_lanthipeptide

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GEGDVTPEGLSSWLGN GGYCTLTKECMPSCN

1

GEGDVTPEGLSSWLGNKGGYCTLTKECMPSCN

32

93.8%

NZ_CP036019.1and 9 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27215_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_JANIOB010000033.1 Lanthipeptides: NQ113_RS28005_lanthipeptideNZ_JH791925.1 Lanthipeptides: IE3_RS28545_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20150_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20145_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26655_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26650_lanthipeptide

Lanthipeptides: EXW52_RS27215_lanthipeptide

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GEGDVTPEGLSSWLGN GGYCTLTKECM SCN

1

GEGDVTPEGLSSWLGNKGGYCTLTKECMSSCN

32

with 112 more sequence matches

Only the first 10 are displayed here.

90.6%

NZ_MLKL01000042.1and 2 others:

NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide

Lanthipeptides: BKK45_RS27570_lanthipeptide

3

GDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GDVTPEGLSSWLGN GGYCTLTKECMPSCN

1

GDVTPEGLSSWLGNKGGYCTLTKECMPSCN

30

59.4%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

9

GLSSWLGNNGGYCTLTKECMPSCN

32

GLSS LGN+G +CTLT ECMPSCN

1

GLSSLLGNDGKFCTLTVECMPSCN

24

56.2%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide

Lanthipeptides: BLI_RS20295_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS LGNNG CT+TKECMPSCN

10

LSKPLGNNGYLCTVTKECMPSCN

32

56.2%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS LGNNG +CT+TKECMPSCN

1

LSRLLGNNGRWCTITKECMPSCN

23

56.2%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS++LGNNGG+CTLTKEC SCN

8

LSNYLGNNGGWCTLTKECQRSCN

30

56.2%

NZ_CP107567.1and 3 others:

NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide

Lanthipeptides: OGH68_RS19760_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS WLGN GG+CTLTKEC P+CN

8

LSDWLGNQGGWCTLTKECQPNCN

30

53.1%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

+S LGN G YCTLT ECMPSCN

10

ISCRLGNKGAYCTLTVECMPSCN

32

53.1%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS +LGN GG+CTLTKEC P+CN

8

LSDFLGNQGGWCTLTKECQPNCN

30

53.1%

NZ_BNBV01000031.1and 1 other:

NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide

Lanthipeptides: IE286_RS22995_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS LGN+GG+CTLTKEC P+CN

8

LSDALGNSGGWCTLTKECQPNCN

30

53.1%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS +LGN GG+CTLTKEC SCN

8

LSDYLGNKGGWCTLTKECQRSCN

30

MIBiG 4.0 matches for DN396_RS23025

56.2%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS+ LGNNGG+CTLTKEC P+CN

8

LSNALGNNGGWCTLTKECQPNCN

30

53.1%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

10

LSSWLGNNGGYCTLTKECMPSCN

32

+S LGN G YCTLT ECMPSCN

6

ISCRLGNKGAYCTLTVECMPSCN

28

23.1%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

21

CTLTKECMPSCN

32

CTL+KEC P+CN

28

CTLSKECQPNCN

39

DN396_RS23040

Leader:

MSKNEKLAKLRNQEFDTKELIGSIDENELKKVAGA

Core:

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

Core with dehydrations:

GDVNPEDhbDhbPADhbPDhbIIGADhbIAVDhbADhaLCysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for DN396_RS23040

100.0%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

85.7%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTI+ ATIA T S+CPTTKCTSRC

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

71.4%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTI +AV+ +CPTTKCTS+C

1

GDVNPETTPATPTI----VAVSLGICPTTKCTSKC

31

with 140 more sequence matches

Only the first 10 are displayed here.

71.1%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

GDVNPETTPAT---PTIIGATIAVTASLCPTTKCTSRC

35

DVNPETTPAT T I A + V+ASLCPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

68.6%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDV+PETTPATPTI+ +A++ LCPTTKCTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTTKCTSKC

32

65.7%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTP T T+ + T S+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKCTSRC

35

65.7%

NZ_MLKL01000042.1:

Lanthipeptides: BKK45_RS27405_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTI +AV+ LCPT CT C

1

GDVNPETTPATPTI----VAVSVKLCPTGVCTKSC

31

65.7%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDV+PETTPATPTI+ + ++ LCPTTKCTS+C

1

GDVSPETTPATPTIV---VGISVGLCPTTKCTSKC

32

65.7%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTP T T+ + T S+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

64.1%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

1

GDVNPETTPAT----PTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTP T P +IGA + ++A+LCPTTKCTS+C

2

GDVNPETTPLTTSSWPCVIGA-VDISANLCPTTKCTSKC

39

62.9%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPET PAT T I A + T LCP+ CTSRC

1

GDVNPETIPATATPILANL--TKELCPSIPCTSRC

33

62.9%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDV+PETTPATPTI+ +A++ LCPT +CTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTNRCTSKC

32

61.5%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

1

GDVNPETT---PATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETT ++ T I A + V+ASLCPTTKCTS+C

2

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

39

MIBiG 4.0 matches for DN396_RS23040

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

16

GATIAVTASLCPTTKCTSRC

35

G + V+A+ CPTTKCTSRC

18

GVAVGVSAAFCPTTKCTSRC

37

25.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

25

LCPTTKCTSRC

35

CPTTKCTS+C

16

FCPTTKCTSKC

26

17.1%

BGC0000582.4 (ADR72962.1):

Linaridin: cypemycin

8

TPATPTI

14

TPATPT+

2

TPATPTV

8

DN396_RS23045

Leader:

MSKNEKLAKLRNQEFDTKELIGLIDEKELKKIAGA

Core:

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

Core with dehydrations:

GDVNPEDhbDhbPDhbDhbADhbVDhbDhbVLVGADhbIDhaICysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for DN396_RS23045

100.0%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

97.1%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTPTTATVTTVLVGATIS+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKCTSRC

35

85.7%

NZ_NVJC01000007.1:

Lanthipeptides: COM38_RS07270_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKC

31

GDVNPETTPTTATVTTVLVGATIS+CPTTKC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKC

31

with 148 more sequence matches

Only the first 10 are displayed here.

71.4%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTP T T+ + AT+SICPTTKCTSRC

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

68.6%

NZ_JANIOB010000033.1:

Lanthipeptides: NQ113_RS28015_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTPTT TVTT A +CPT +CTSRC

1

GDVNPETTPTTHTVTTQNFTA---LCPTPRCTSRC

32

65.7%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTP T T+ V +G ICPTTKCTS+C

1

GDVNPETTPATPTIVAVSLG----ICPTTKCTSKC

31

65.7%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTP T T+ + T S+CPTTKCTSRC

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

63.2%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

GDVNPETTP-TTATVTTVLVGATIS--ICPTTKCTSRC

35

DVNPETTP TT++ T + G T+S +CPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

60.0%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDV+PETTP T T+ +VG ++ +CPTTKCTS+C

1

GDVSPETTPATPTI---VVGISVGLCPTTKCTSKC

32

59.0%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

1

GDVNPETT-PTTATVTTVLVGATIS--ICPTTKCTSRC

35

GDVNPETT TT++ T + G T+S +CPTTKCTS+C

2

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

39

57.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPET P AT T +L T +CP+ CTSRC

1

GDVNPETIP--ATATPILANLTKELCPSIPCTSRC

33

57.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDV+PETTP T T+ +V ++ +CPTTKCTS+C

1

GDVSPETTPATPTI---VVAISVGLCPTTKCTSKC

32

57.1%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20280_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GD+NPET P AT T +LV T +CP+ CTSRC

1

GDMNPETIP--ATPTPILVNLTKELCPSIPCTSRC

33

MIBiG 4.0 matches for DN396_RS23045

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

17

VLVGATISICPTTKCTSRC

35

V VG + + CPTTKCTSRC

19

VAVGVSAAFCPTTKCTSRC

37

25.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

25

ICPTTKCTSRC

35

CPTTKCTS+C

16

FCPTTKCTSKC

26

DN396_RS23050

Leader:

MSKNEKLAKLRNQEFDTKELIGSIDENELKKVAGA

Core:

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

Core with dehydrations:

GDVNPEDhbDhbPADhbPDhbIVEADhbIAADhbVDhaICysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for DN396_RS23050

100.0%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

85.7%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTI+ ATIA T S+CPTTKCTSRC

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

74.3%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTIV A ++ ICPTTKCTS+C

1

GDVNPETTPATPTIV----AVSLGICPTTKCTSKC

31

with 146 more sequence matches

Only the first 10 are displayed here.

71.4%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDV+PETTPATPTIV +A +V +CPTTKCTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTTKCTSKC

32

71.4%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTP T T+ + AT+SICPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

68.6%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTP T T+ + AT+S+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKCTSRC

35

68.6%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDV+PETTPATPTIV + +V +CPTTKCTS+C

1

GDVSPETTPATPTIV---VGISVGLCPTTKCTSKC

32

65.7%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDV+PETTPATPTIV +A +V +CPT +CTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTNRCTSKC

32

65.7%

NZ_MLKL01000042.1:

Lanthipeptides: BKK45_RS27405_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTIV A +V +CPT CT C

1

GDVNPETTPATPTIV----AVSVKLCPTGVCTKSC

31

60.5%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

GDVNPETTPAT---PTIVEATIAATVSICPTTKCTSRC

35

DVNPETTPAT T + A + + S+CPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

57.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPET PAT T + A + T +CP+ CTSRC

1

GDVNPETIPATATPILANL--TKELCPSIPCTSRC

33

57.1%

NZ_JANIOB010000033.1:

Lanthipeptides: NQ113_RS28015_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTP T T+ A +CPT +CTSRC

1

GDVNPETTPTTHTVTTQNFTA---LCPTPRCTSRC

32

57.1%

NZ_NVJC01000007.1:

Lanthipeptides: COM38_RS07270_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKC

31

GDVNPETTP T T+ + AT+S+CPTTKC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKC

31

MIBiG 4.0 matches for DN396_RS23050

37.8%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

15

VEATIAATVS--ICPTTKCTSRC

35

++A +A VS CPTTKCTSRC

15

IQAGVAVGVSAAFCPTTKCTSRC

37

25.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

25

ICPTTKCTSRC

35

CPTTKCTS+C

16

FCPTTKCTSKC

26

20.0%

BGC0000582.4 (ADR72962.1):

Linaridin: cypemycin

8

TPATPTIVEATIAAT

22

TPATPT+ + I +

2

TPATPTVAQFVIQGS

16

DN396_RS30025

Leader:

KNVVDTPLIVTLNGILTSNINNNISMTFQAG

Core:

DCISVKITIGSSNATTDTVVQVDIFLCFIVSK

Core with dehydrations:

DCysIDhaVKIDhbIGDhaDhaNADhbDhbDDhbVVQVDIFLCysFIVDhaK

antiSMASH-DB 4.0 matches for DN396_RS30025

18.8%

NZ_CP053021.1:

Lassopeptides: HH800_RS11690_lassopeptide

10

GSSNATTDTVVQV

22

G S DTV+Q+

1

GGSPGANDTVIQL

13

allorf_10523_10711

Leader:

MVRSYSRYNLCFRNLMKIIGE

Core:

RGLSITHTTITRRVYCPKFVSIQVKPLIISFTVWIDVIHRD

Core with dehydrations:

RGLDhaIDhbHDhbDhbIDhbRRVYCysPKFVDhaIQVKPLIIDhaFDhbVWIDVIHRD

antiSMASH-DB 4.0 matches for allorf_10523_10711

43.9%

NZ_CM000721.1:

Lanthipeptides: BCERE0010_RS29580_lanthipeptide

1

RGLSITHTTITRRVYCPK

18

RGLSITHTTITRRVYCPK

1

RGLSITHTTITRRVYCPK

18

17.1%

NZ_AP025017.1:

Lanthipeptides: allorf_1459483_1459698_lanthipeptide

1

RGLSITHTTITRRVYCP

17

RGL++T + RV C

9

RGLALTQGSARGRVNCS

25

allorf_12454_12516

Leader:

MIYNNIGLSLSIGG

Core:

RESCNI

Core with dehydrations:

REDhaCysNI

antiSMASH-DB 4.0 matches for allorf_12454_12516

100.0%

NZ_CM000721.1and 5 others:

NZ_CP015591.1 Lanthipeptides: allorf_13725_13787_lanthipeptideNZ_CP078085.1 Lanthipeptides: allorf_18236_18298_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: allorf_10964_11026_lanthipeptideNZ_JAOPQQ010000020.1 Lanthipeptides: allorf_25273_25335_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: allorf_12454_12516_lanthipeptide

Lanthipeptides: allorf_5190336_5190398_lanthipeptide

1

RESCNI

6

RESCNI

1

RESCNI

6

Lanthipeptide(s) for DN396_RS23065

DN396_RS23025

Leader:

MSSSKKVVEAWKNPVERSKNEDAPNHPAGEVDSKEIQSLFGA

DN396_RS23030

Leader:

MSSSKKVVEAWKNPVERSKNEDAPNHPAGEVDSKEIQSLFGA

DN396_RS23035

Leader:

MSSSKKVVEAWKNPVERSKNEDAPNHPAGEVDSKEIQSLFGA

Shared core:

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

Core with dehydrations:

GEGDVDhbPEGLDhaDhaWLGNNGGYCysDhbLDhbKECysMPDhaCysN

antiSMASH-DB 4.0 matches for DN396_RS23025

100.0%

NZ_CP015591.1and 19 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27560_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29375_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29370_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29365_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29955_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29950_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29945_lanthipeptideNZ_JACYOF010000027.1 Lanthipeptides: IGI01_RS29005_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29780_lanthipeptideNZ_NVJC01000007.1 Lanthipeptides: COM38_RS07400_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23035_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23030_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23025_lanthipeptide

Lanthipeptides: A7A70_RS27565_lanthipeptide

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

96.9%

NC_018499.1and 7 others:

NC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27860_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27855_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27850_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25275_lanthipeptideNZ_JAOPQW010000026.1 Lanthipeptides: OCD10_RS25270_lanthipeptide

Lanthipeptides: BCK_RS27860_lanthipeptide

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GEGDVTPEGLSSWLGN GGYCTLTKECMPSCN

1

GEGDVTPEGLSSWLGNKGGYCTLTKECMPSCN

32

93.8%

NZ_CP036019.1and 9 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27215_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27210_lanthipeptideNZ_JANIOB010000033.1 Lanthipeptides: NQ113_RS28005_lanthipeptideNZ_JH791925.1 Lanthipeptides: IE3_RS28545_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20150_lanthipeptideNZ_NUML01000015.1 Lanthipeptides: COD66_RS20145_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26655_lanthipeptideNZ_NUVR01000040.1 Lanthipeptides: COI88_RS26650_lanthipeptide

Lanthipeptides: EXW52_RS27215_lanthipeptide

1

GEGDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GEGDVTPEGLSSWLGN GGYCTLTKECM SCN

1

GEGDVTPEGLSSWLGNKGGYCTLTKECMSSCN

32

with 112 more sequence matches

Only the first 10 are displayed here.

90.6%

NZ_MLKL01000042.1and 2 others:

NZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27565_lanthipeptideNZ_MLKL01000042.1 Lanthipeptides: BKK45_RS27560_lanthipeptide

Lanthipeptides: BKK45_RS27570_lanthipeptide

3

GDVTPEGLSSWLGNNGGYCTLTKECMPSCN

32

GDVTPEGLSSWLGN GGYCTLTKECMPSCN

1

GDVTPEGLSSWLGNKGGYCTLTKECMPSCN

30

59.4%

NZ_LT630004.1:

Lanthipeptides: BQ5796_RS17475_lanthipeptide

9

GLSSWLGNNGGYCTLTKECMPSCN

32

GLSS LGN+G +CTLT ECMPSCN

1

GLSSLLGNDGKFCTLTVECMPSCN

24

56.2%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20295_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07805_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08835_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11865_lanthipeptide

Lanthipeptides: BLI_RS20295_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS LGNNG CT+TKECMPSCN

10

LSKPLGNNGYLCTVTKECMPSCN

32

56.2%

NZ_CP050134.2and 3 others:

NZ_EQ973330.1 Lanthipeptides: CORMATOL_RS10565_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptideNZ_LR134504.1 Lanthipeptides: EL293_RS07240_lanthipeptide

Lanthipeptides: HBA49_RS00770_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS LGNNG +CT+TKECMPSCN

1

LSRLLGNNGRWCTITKECMPSCN

23

56.2%

NZ_CP084530.1and 1 other:

NZ_CP084530.1 Lanthipeptides: LDO05_RS02075_lanthipeptide

Lanthipeptides: LDO05_RS02075_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS++LGNNGG+CTLTKEC SCN

8

LSNYLGNNGGWCTLTKECQRSCN

30

56.2%

NZ_CP107567.1and 3 others:

NZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptideNZ_CP107567.1 Lanthipeptides: OGH68_RS19760_lanthipeptide

Lanthipeptides: OGH68_RS19760_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS WLGN GG+CTLTKEC P+CN

8

LSDWLGNQGGWCTLTKECQPNCN

30

53.1%

NC_002570.2and 3 others:

NC_002570.2 Lanthipeptides: AYT26_RS02480_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptideNZ_CP040441.1 Lanthipeptides: FED51_RS02600_lanthipeptide

Lanthipeptides: AYT26_RS02480_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

+S LGN G YCTLT ECMPSCN

10

ISCRLGNKGAYCTLTVECMPSCN

32

53.1%

NZ_AKXV01000031.1and 4 others:

NZ_AKXV01000031.1 Lanthipeptides: Y19_RS0109895_lanthipeptideNZ_JABBGE010000004.1 Lanthipeptides: HHL19_RS13545_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptideNZ_LMEI01000006.1 Lanthipeptides: ASC82_RS06140_lanthipeptide

Lanthipeptides: Y19_RS0109895_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS +LGN GG+CTLTKEC P+CN

8

LSDFLGNQGGWCTLTKECQPNCN

30

53.1%

NZ_BNBV01000031.1and 1 other:

NZ_BNBV01000031.1 Lanthipeptides: IE286_RS22995_lanthipeptide

Lanthipeptides: IE286_RS22995_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS LGN+GG+CTLTKEC P+CN

8

LSDALGNSGGWCTLTKECQPNCN

30

53.1%

NZ_LT985747.1and 1 other:

NZ_LT985747.1 Lanthipeptides: C8268_RS00165_lanthipeptide

Lanthipeptides: C8268_RS00165_lanthipeptide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS +LGN GG+CTLTKEC SCN

8

LSDYLGNKGGWCTLTKECQRSCN

30

MIBiG 4.0 matches for DN396_RS23025

56.2%

BGC0002110.3 (QKV49893.1):

Lanthipeptide: birimositide

10

LSSWLGNNGGYCTLTKECMPSCN

32

LS+ LGNNGG+CTLTKEC P+CN

8

LSNALGNNGGWCTLTKECQPNCN

30

53.1%

BGC0000517.4 (BAB04173.1):

Lanthipeptide: haloduracin β or haloduracin α

10

LSSWLGNNGGYCTLTKECMPSCN

32

+S LGN G YCTLT ECMPSCN

6

ISCRLGNKGAYCTLTVECMPSCN

28

23.1%

BGC0001229.4 (SBI_06990):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

21

CTLTKECMPSCN

32

CTL+KEC P+CN

28

CTLSKECQPNCN

39

DN396_RS23040

Leader:

MSKNEKLAKLRNQEFDTKELIGSIDENELKKVAGA

Core:

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

Core with dehydrations:

GDVNPEDhbDhbPADhbPDhbIIGADhbIAVDhbADhaLCysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for DN396_RS23040

100.0%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

85.7%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTI+ ATIA T S+CPTTKCTSRC

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

71.4%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTI +AV+ +CPTTKCTS+C

1

GDVNPETTPATPTI----VAVSLGICPTTKCTSKC

31

with 140 more sequence matches

Only the first 10 are displayed here.

71.1%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

GDVNPETTPAT---PTIIGATIAVTASLCPTTKCTSRC

35

DVNPETTPAT T I A + V+ASLCPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

68.6%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDV+PETTPATPTI+ +A++ LCPTTKCTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTTKCTSKC

32

65.7%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTP T T+ + T S+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKCTSRC

35

65.7%

NZ_MLKL01000042.1:

Lanthipeptides: BKK45_RS27405_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTPATPTI +AV+ LCPT CT C

1

GDVNPETTPATPTI----VAVSVKLCPTGVCTKSC

31

65.7%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDV+PETTPATPTI+ + ++ LCPTTKCTS+C

1

GDVSPETTPATPTIV---VGISVGLCPTTKCTSKC

32

65.7%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTP T T+ + T S+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

64.1%

NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

1

GDVNPETTPAT----PTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETTP T P +IGA + ++A+LCPTTKCTS+C

2

GDVNPETTPLTTSSWPCVIGA-VDISANLCPTTKCTSKC

39

62.9%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPET PAT T I A + T LCP+ CTSRC

1

GDVNPETIPATATPILANL--TKELCPSIPCTSRC

33

62.9%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

GDV+PETTPATPTI+ +A++ LCPT +CTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTNRCTSKC

32

61.5%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

1

GDVNPETT---PATPTIIGATIAVTASLCPTTKCTSRC

35

GDVNPETT ++ T I A + V+ASLCPTTKCTS+C

2

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

39

MIBiG 4.0 matches for DN396_RS23040

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

16

GATIAVTASLCPTTKCTSRC

35

G + V+A+ CPTTKCTSRC

18

GVAVGVSAAFCPTTKCTSRC

37

25.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

25

LCPTTKCTSRC

35

CPTTKCTS+C

16

FCPTTKCTSKC

26

17.1%

BGC0000582.4 (ADR72962.1):

Linaridin: cypemycin

8

TPATPTI

14

TPATPT+

2

TPATPTV

8

DN396_RS23045

Leader:

MSKNEKLAKLRNQEFDTKELIGLIDEKELKKIAGA

Core:

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

Core with dehydrations:

GDVNPEDhbDhbPDhbDhbADhbVDhbDhbVLVGADhbIDhaICysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for DN396_RS23045

100.0%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

97.1%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTPTTATVTTVLVGATIS+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKCTSRC

35

85.7%

NZ_NVJC01000007.1:

Lanthipeptides: COM38_RS07270_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKC

31

GDVNPETTPTTATVTTVLVGATIS+CPTTKC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKC

31

with 148 more sequence matches

Only the first 10 are displayed here.

71.4%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTP T T+ + AT+SICPTTKCTSRC

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

68.6%

NZ_JANIOB010000033.1:

Lanthipeptides: NQ113_RS28015_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTPTT TVTT A +CPT +CTSRC

1

GDVNPETTPTTHTVTTQNFTA---LCPTPRCTSRC

32

65.7%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTP T T+ V +G ICPTTKCTS+C

1

GDVNPETTPATPTIVAVSLG----ICPTTKCTSKC

31

65.7%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPETTP T T+ + T S+CPTTKCTSRC

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

63.2%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

GDVNPETTP-TTATVTTVLVGATIS--ICPTTKCTSRC

35

DVNPETTP TT++ T + G T+S +CPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

60.0%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDV+PETTP T T+ +VG ++ +CPTTKCTS+C

1

GDVSPETTPATPTI---VVGISVGLCPTTKCTSKC

32

59.0%

NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

1

GDVNPETT-PTTATVTTVLVGATIS--ICPTTKCTSRC

35

GDVNPETT TT++ T + G T+S +CPTTKCTS+C

2

GDVNPETTILTTSSWTCITAGVTVSASLCPTTKCTSQC

39

57.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDVNPET P AT T +L T +CP+ CTSRC

1

GDVNPETIP--ATATPILANLTKELCPSIPCTSRC

33

57.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GDV+PETTP T T+ +V ++ +CPTTKCTS+C

1

GDVSPETTPATPTI---VVAISVGLCPTTKCTSKC

32

57.1%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20280_lanthipeptide

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

GD+NPET P AT T +LV T +CP+ CTSRC

1

GDMNPETIP--ATPTPILVNLTKELCPSIPCTSRC

33

MIBiG 4.0 matches for DN396_RS23045

35.1%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

17

VLVGATISICPTTKCTSRC

35

V VG + + CPTTKCTSRC

19

VAVGVSAAFCPTTKCTSRC

37

25.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

25

ICPTTKCTSRC

35

CPTTKCTS+C

16

FCPTTKCTSKC

26

DN396_RS23050

Leader:

MSKNEKLAKLRNQEFDTKELIGSIDENELKKVAGA

Core:

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

Core with dehydrations:

GDVNPEDhbDhbPADhbPDhbIVEADhbIAADhbVDhaICysPDhbDhbKCysDhbDhaRCys

antiSMASH-DB 4.0 matches for DN396_RS23050

100.0%

NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

85.7%

NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTI+ ATIA T S+CPTTKCTSRC

1

GDVNPETTPATPTIIGATIAVTASLCPTTKCTSRC

35

74.3%

NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTIV A ++ ICPTTKCTS+C

1

GDVNPETTPATPTIV----AVSLGICPTTKCTSKC

31

with 146 more sequence matches

Only the first 10 are displayed here.

71.4%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDV+PETTPATPTIV +A +V +CPTTKCTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTTKCTSKC

32

71.4%

NZ_QNUC01000031.1and 1 other:

NZ_QNUC01000031.1 Lanthipeptides: DN396_RS23045_lanthipeptide

Lanthipeptides: DN396_RS23045_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTP T T+ + AT+SICPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISICPTTKCTSRC

35

68.6%

NZ_CP085411.1and 1 other:

NZ_CP085411.1 Lanthipeptides: LIT28_RS29915_lanthipeptide

Lanthipeptides: LIT28_RS29915_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTP T T+ + AT+S+CPTTKCTSRC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKCTSRC

35

68.6%

NZ_NUML01000015.1:

Lanthipeptides: COD66_RS20140_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDV+PETTPATPTIV + +V +CPTTKCTS+C

1

GDVSPETTPATPTIV---VGISVGLCPTTKCTSKC

32

65.7%

NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDV+PETTPATPTIV +A +V +CPT +CTS+C

1

GDVSPETTPATPTIV---VAISVGLCPTNRCTSKC

32

65.7%

NZ_MLKL01000042.1:

Lanthipeptides: BKK45_RS27405_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTPATPTIV A +V +CPT CT C

1

GDVNPETTPATPTIV----AVSVKLCPTGVCTKSC

31

60.5%

NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

1

GDVNPETTPAT---PTIVEATIAATVSICPTTKCTSRC

35

DVNPETTPAT T + A + + S+CPTTKCTSRC

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTKCTSRC

38

57.1%

NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPET PAT T + A + T +CP+ CTSRC

1

GDVNPETIPATATPILANL--TKELCPSIPCTSRC

33

57.1%

NZ_JANIOB010000033.1:

Lanthipeptides: NQ113_RS28015_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKCTSRC

35

GDVNPETTP T T+ A +CPT +CTSRC

1

GDVNPETTPTTHTVTTQNFTA---LCPTPRCTSRC

32

57.1%

NZ_NVJC01000007.1:

Lanthipeptides: COM38_RS07270_lanthipeptide

1

GDVNPETTPATPTIVEATIAATVSICPTTKC

31

GDVNPETTP T T+ + AT+S+CPTTKC

1

GDVNPETTPTTATVTTVLVGATISVCPTTKC

31

MIBiG 4.0 matches for DN396_RS23050

37.8%

BGC0001229.4 (SBI_06989):

Lanthipeptide: SBI-06990 A1 or SBI-06989 A2

15

VEATIAATVS--ICPTTKCTSRC

35

++A +A VS CPTTKCTSRC

15

IQAGVAVGVSAAFCPTTKCTSRC

37

25.7%

BGC0002110.3 (QKV49894.1):

Lanthipeptide: birimositide

25

ICPTTKCTSRC

35

CPTTKCTS+C

16

FCPTTKCTSKC

26

20.0%

BGC0000582.4 (ADR72962.1):

Linaridin: cypemycin

8

TPATPTIVEATIAAT

22

TPATPT+ + I +

2

TPATPTVAQFVIQGS

16

DN396_RS30025

Leader:

KNVVDTPLIVTLNGILTSNINNNISMTFQAG

Core:

DCISVKITIGSSNATTDTVVQVDIFLCFIVSK

Core with dehydrations:

DCysIDhaVKIDhbIGDhaDhaNADhbDhbDDhbVVQVDIFLCysFIVDhaK

antiSMASH-DB 4.0 matches for DN396_RS30025

18.8%

NZ_CP053021.1:

Lassopeptides: HH800_RS11690_lassopeptide

10

GSSNATTDTVVQV

22

G S DTV+Q+

1

GGSPGANDTVIQL

13

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

CatR

Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 20.67 out of 25.31

Confidence: medium

IolR

Description: Regulator of the inositol catabolism
Species: Caulobacter crescentus CB15
Score: 19.66 out of 23.79

Confidence: medium

Additional weak hits (3):

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 21.71 out of 33.73

Confidence: weak

RicR

Description: Copper-responsive regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 22.36 out of 32.93

Confidence: weak

ZuR variant 2

Description: Zinc-responsive repressor
Species: Pseudomonas protegens Pf-5
Score: 25.64 out of 33.14

Confidence: weak

Lanthipeptides

TFBS Finder

Core peptide predictions

DN396_RS23025 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 3210.4 Da

Molecular weight: 3212.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3230.5 Da N = 1; 3248.5 Da N = 2; 3266.6 Da N = 3

DN396_RS23030 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 3210.4 Da

Molecular weight: 3212.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3230.5 Da N = 1; 3248.5 Da N = 2; 3266.6 Da N = 3

DN396_RS23035 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 3210.4 Da

Molecular weight: 3212.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3230.5 Da N = 1; 3248.5 Da N = 2; 3266.6 Da N = 3

DN396_RS23040 - Class II

Cleavage pHMM score: 3.40

RODEO score: 0

Monoisotopic mass: 3291.7 Da

Molecular weight: 3293.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3311.8 Da N = 1; 3329.8 Da N = 2; 3347.8 Da N = 3; 3365.8 Da N = 4; 3383.8 Da N = 5; 3401.9 Da N = 6; 3419.9 Da N = 7; 3437.9 Da N = 8

DN396_RS23045 - Class II

Cleavage pHMM score: 3.60

RODEO score: 0

Monoisotopic mass: 3303.7 Da

Molecular weight: 3305.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3323.8 Da N = 1; 3341.8 Da N = 2; 3359.8 Da N = 3; 3377.8 Da N = 4; 3395.8 Da N = 5; 3413.9 Da N = 6; 3431.9 Da N = 7; 3449.9 Da N = 8; 3467.9 Da N = 9; 3485.9 Da N = 10

DN396_RS23050 - Class II

Cleavage pHMM score: 3.40

RODEO score: 0

Monoisotopic mass: 3349.7 Da

Molecular weight: 3351.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3369.8 Da N = 1; 3387.8 Da N = 2; 3405.8 Da N = 3; 3423.9 Da N = 4; 3441.9 Da N = 5; 3459.9 Da N = 6; 3477.9 Da N = 7; 3495.9 Da N = 8

DN396_RS30025 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 3271.8 Da

Molecular weight: 3273.8 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3291.8 Da N = 1; 3309.8 Da N = 2; 3327.8 Da N = 3; 3345.9 Da N = 4; 3363.9 Da N = 5; 3381.9 Da N = 6

DN396_RS23025 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 3210.4 Da

Molecular weight: 3212.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3230.5 Da N = 1; 3248.5 Da N = 2; 3266.6 Da N = 3

DN396_RS23030 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 3210.4 Da

Molecular weight: 3212.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3230.5 Da N = 1; 3248.5 Da N = 2; 3266.6 Da N = 3

DN396_RS23035 - Class II

Cleavage pHMM score: -1.80

RODEO score: 0

Monoisotopic mass: 3210.4 Da

Molecular weight: 3212.5 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3230.5 Da N = 1; 3248.5 Da N = 2; 3266.6 Da N = 3

DN396_RS23040 - Class II

Cleavage pHMM score: 3.40

RODEO score: 0

Monoisotopic mass: 3291.7 Da

Molecular weight: 3293.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3311.8 Da N = 1; 3329.8 Da N = 2; 3347.8 Da N = 3; 3365.8 Da N = 4; 3383.8 Da N = 5; 3401.9 Da N = 6; 3419.9 Da N = 7; 3437.9 Da N = 8

DN396_RS23045 - Class II

Cleavage pHMM score: 3.60

RODEO score: 0

Monoisotopic mass: 3303.7 Da

Molecular weight: 3305.7 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3323.8 Da N = 1; 3341.8 Da N = 2; 3359.8 Da N = 3; 3377.8 Da N = 4; 3395.8 Da N = 5; 3413.9 Da N = 6; 3431.9 Da N = 7; 3449.9 Da N = 8; 3467.9 Da N = 9; 3485.9 Da N = 10

DN396_RS23050 - Class II

Cleavage pHMM score: 3.40

RODEO score: 0

Monoisotopic mass: 3349.7 Da

Molecular weight: 3351.8 Da

Number of bridges: 3

Alternative weights: (assuming N unmodified Ser/Thr residues); 3369.8 Da N = 1; 3387.8 Da N = 2; 3405.8 Da N = 3; 3423.9 Da N = 4; 3441.9 Da N = 5; 3459.9 Da N = 6; 3477.9 Da N = 7; 3495.9 Da N = 8

DN396_RS30025 - Class II

Cleavage pHMM score: -6.80

RODEO score: 0

Monoisotopic mass: 3271.8 Da

Molecular weight: 3273.8 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3291.8 Da N = 1; 3309.8 Da N = 2; 3327.8 Da N = 3; 3345.9 Da N = 4; 3363.9 Da N = 5; 3381.9 Da N = 6

allorf_10523_10711 - Class II

Cleavage pHMM score: -6.40

RODEO score: 0

Monoisotopic mass: 4663.7 Da

Molecular weight: 4666.5 Da

Number of bridges: 1

Alternative weights: (assuming N unmodified Ser/Thr residues); 4684.5 Da N = 1; 4702.5 Da N = 2; 4720.6 Da N = 3; 4738.6 Da N = 4; 4756.6 Da N = 5; 4774.6 Da N = 6; 4792.6 Da N = 7

allorf_12454_12516 - Class II

Cleavage pHMM score: -4.20

RODEO score: 0

Monoisotopic mass: 702.3 Da

Molecular weight: 702.8 Da

Number of bridges: 1

TFBS definitions

Regulator	Description
CatR	H2O2-responsive repressor
IolR	Regulator of the inositol catabolism
ToxT	Regulator of MSHA biosynthesis

NZ_QNUC01000033.1 - Region 1 - RiPP-like

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Location: 71,958 - 82,257 nt. (total: 10,300 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: aminotransferase

DN396_RS24305: aminotransferase

smcogs: SMCOG1019: aminotransferase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000721.4	0.27	saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0001964.2	0.25	PKS	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0000172.5	0.23	PKS	Basiliskamide A, Basiliskamide B	Brevibacillus laterosporus PE36
BGC0000381.5	0.23	NRPS	lichenysin	Bacillus licheniformis DSM 13 = ATCC 14580
BGC0000433.5	0.22	NRPS	surfactin	Bacillus velezensis FZB42
BGC0000455.6	0.22	NRPS, saccharide	vancomycin	Amycolatopsis orientalis HCCB10007 (ATCC43491)
BGC0002588.2	0.22	other (other)	enduracididine	uncultured bacterium
BGC0001233.5	0.22	NRPS	feglymycin	Streptomyces sp. DSM 11171
BGC0001461.5	0.22	NRPS	Actinoidin B	Amycolatopsis keratiniphila subsp. nogabecina
BGC0001459.5	0.22	NRPS	decaplanin	Amycolatopsis regifaucium

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000721.4	0.27	saccharide	tobramycin	Streptoalloteichus tenebrarius
BGC0001964.2	0.25	PKS	alkylpyrone-407, alkylpyrone-393	Cystobacterineae bacterium
BGC0000172.5	0.23	PKS	Basiliskamide A, Basiliskamide B	Brevibacillus laterosporus PE36
BGC0000381.5	0.23	NRPS	lichenysin	Bacillus licheniformis DSM 13 = ATCC 14580
BGC0000433.5	0.22	NRPS	surfactin	Bacillus velezensis FZB42
BGC0000455.6	0.22	NRPS, saccharide	vancomycin	Amycolatopsis orientalis HCCB10007 (ATCC43491)
BGC0002588.2	0.22	other (other)	enduracididine	uncultured bacterium
BGC0001233.5	0.22	NRPS	feglymycin	Streptomyces sp. DSM 11171
BGC0001461.5	0.22	NRPS	Actinoidin B	Amycolatopsis keratiniphila subsp. nogabecina
BGC0001459.5	0.22	NRPS	decaplanin	Amycolatopsis regifaucium

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 24.26 out of 26.06

Confidence: strong

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 24.87 out of 32.93

Confidence: medium

Additional weak hits (2):

MntR

Description: Manganese transport regulator
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.60 out of 39.62

Confidence: weak

DosR

Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 18.97 out of 29.51

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
LexA variant 3	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes

NZ_QNUC01000035.1 - Region 1 - terpene

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Location: 29,742 - 51,595 nt. (total: 21,854 nt) Show pHMM detection rules used

terpene: (PT_phytoene_like or phytoene_synt or Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA or TS_Pyr4)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Terpene

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase

DN396_RS24975: aldehyde dehydrogenase

smcogs: SMCOG1017: aldehyde dehydrogenase

DN396_RS24980: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

Lyases: lyase

DN396_RS24950: argininosuccinate lyase/adenylosuccinate lyase

smcogs: SMCOG1063: argininosuccinate lyase/adenylosuccinate lyase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000917.3	0.52	other (other)	molybdenum cofactor	Rhodobacter capsulatus
BGC0000888.5	0.49	other (other)	bacilysin	Bacillus sp. CS93
BGC0001928.2	0.46	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0000916.5	0.46	other (other)	molybdenum cofactor	Staphylococcus carnosus
BGC0000812.3	0.45	other (other)	huperzine A	Shiraia sp. slf14
BGC0000231.5	0.42	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001605.3	0.42	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001197.5	0.42	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000234.5	0.41	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0002138.2	0.40	PKS	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000917.3	0.52	other (other)	molybdenum cofactor	Rhodobacter capsulatus
BGC0000888.5	0.49	other (other)	bacilysin	Bacillus sp. CS93
BGC0001928.2	0.46	other (other)	(2R,3S,4S)-5-fluoro-2,3,4-trihydroxypentanoic acid	Streptomyces sp. MA37
BGC0000916.5	0.46	other (other)	molybdenum cofactor	Staphylococcus carnosus
BGC0000812.3	0.45	other (other)	huperzine A	Shiraia sp. slf14
BGC0000231.5	0.42	PKS	griseusin A, griseusin B	Streptomyces griseus
BGC0001605.3	0.42	terpene	gibberellin	Sinorhizobium fredii NGR234
BGC0001197.5	0.42	PKS	frankiamicin	Frankia sp. EAN1pec
BGC0000234.5	0.41	PKS	jadomycin	Streptomyces venezuelae ATCC 10712
BGC0002138.2	0.40	PKS	fuelimycin A, fuelimicin B, fuelimicin C	Streptomyces albireticuli NRRL B-1670

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Detailed terpene predictions

Product predictions:

Class	Subclass	Product name	Chain length	Initial cyclisations	Functional groups
triterpene	hopanoid		C30	hopanoid skeleton	unknown
triterpene	polypodane		C30	polypodane skeleton	unknown

Genes with terpene domains:

DN396_RS24990: T2TS

Domain 1 (4 - 614): Type 2 terpene synthase

Subtype: Squalene substrate

Reactions:: squalene → hopanoid; squalene → polypodane

Terpene

Glossary

No acronyms to display

NZ_QNUC01000004.1 - Region 1 - RiPP-like

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Location: 35,423 - 45,689 nt. (total: 10,267 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

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Gene overview

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Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Hydrolases: hydrolase

DN396_RS01890: beta-lactamase

smcogs: SMCOG1053: beta-lactamase

Similar gene clusters

Analysis type:

Reference	RiPP-like	Similarity score	Type	Compound(s)	Organism
BGC0001994.4		0.35	other (other)	β-ethynylserine	Streptomyces cattleya NRRL 8057 = DSM 46488

Reference	Aggregated	Similarity score	Type	Compound(s)	Organism
BGC0001994.4		0.35	other (other)	β-ethynylserine	Streptomyces cattleya NRRL 8057 = DSM 46488

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

NZ_QNUC01000043.1 - Region 1 - NRPS

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Location: 1 - 48,241 nt. (total: 48,241 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

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KnownClusterBlast

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TFBS Finder

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: PPTase

DN396_RS27470: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1012: 4'-phosphopantetheinyl transferase

Hydrolases: esterase

DN396_RS27475: thioesterase

smcogs: SMCOG1004: thioesterase

Ligases: ligase

DN396_RS27455: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

DN396_RS27460: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

DN396_RS27465: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001833.4	0.75	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0002135.2	0.75	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001128.4	0.73	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001133.4	0.73	NRPS	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0002075.3	0.73	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001758.4	0.73	NRPS	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0002286.3	0.73	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.5	0.73	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.4	0.73	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.4	0.73	NRPS	xenematide	Xenorhabdus nematophila AN6/1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001833.4	0.75	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0002135.2	0.75	NRPS	bovienimide A	Xenorhabdus bovienii SS-2004
BGC0001128.4	0.73	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001133.4	0.73	NRPS	taxlllaid A	Xenorhabdus bovienii SS-2004
BGC0002075.3	0.73	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0001758.4	0.73	NRPS	rhizomide A, rhizomide B, rhizomide C	Paraburkholderia rhizoxinica HKI 454
BGC0002286.3	0.73	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0001135.5	0.73	NRPS	bicornutin A1, bicornutin A2	Xenorhabdus budapestensis
BGC0001132.4	0.73	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001825.4	0.73	NRPS	xenematide	Xenorhabdus nematophila AN6/1

Similar known clusters from MIBiG 4.0

No significant matches found.

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 15.13 out of 18.16

Confidence: strong

SypG

Description: Regulator of biofilm formation and host colonization
Species: Vibrio fischeri ES114
Score: 23.19 out of 29.25

Confidence: medium

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 23.94 out of 32.93

Confidence: medium

Additional weak hits (4):

HexR

Description: Glucose-responsive regulator
Species: Shewanella oneidensis MR-1
Score: 24.98 out of 31.73

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.61 out of 30.25

Confidence: weak

DosR

Description: Hypoxia stress response regulator
Species: Mycobacterium tuberculosis H37Rv
Score: 20.52 out of 29.51

Confidence: weak

NrtR

Description: NAD synthesis repressor
Species: Streptomyces coelicolor
Score: 23.70 out of 35.63

Confidence: weak

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

TFBS Finder

Predicted core structure(s)

For candidate cluster 1, location 0 - 48241:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Thr) + (X - Ala) + (Ser - Leu - D-X - Glu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

DN396_RS27455: Thr

Search NORINE for peptide: strict or relaxed

AMP-binding (457..866): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: LSTHFDFSVWEGNQIFGGEINMYGITETTVHVTY
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

DN396_RS27460: X - Ala

Search NORINE for peptide: strict or relaxed

AMP-binding (466..870): X

nrpys: Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: YWMTFDVSVWEWQFFSGGETNFYGPTEATIYVNA
Nearest Stachelhaus code(s):: Glu DVWHFGRINK (71% 8Å match); Gln DAWQFGLIDK (65% 8Å match)
Stachelhaus code match:: 70% (weak)

AMP-binding (1527..1919): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: ala (Ala)

Stachelhaus prediction details:

Stachelhaus sequence:: MWATFDLSVFEVNTNLAGEYNLYGPSEDTTYSTY
Nearest Stachelhaus code(s):: Ala DLFNNALTYK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

DN396_RS27465: Ser - Leu - X - Glu

Search NORINE for peptide: strict or relaxed

AMP-binding (496..901): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: ser (Ser)
Single AA prediction:: ser (Ser)

Stachelhaus prediction details:

Stachelhaus sequence:: RWMTFDVSVWEWHFFTSGEINLYGPTEATVDVTY
Nearest Stachelhaus code(s):: Ser DVWHFSLVDK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1558..1945): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: MWHAFDSAVQEPFAITGGDINQYGPSENTVVTTD
Nearest Stachelhaus code(s):: Pro DVQFIAQVVK (56% 8Å match)
Stachelhaus code match:: 80% (moderate)

AMP-binding (2600..3000): X

nrpys: Gln, Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: LGLAFDASIQQMDILVGGEYNVYGPTECTVDATC
Nearest Stachelhaus code(s):: Gln or Glu DAQDLGVVDK (88% 8Å match); Ile DAQDLGVVDK (85% 8Å match); Gln DAQDLGVVDK (79% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (4115..4515): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: LGLAFDVSIQQMDMLVGGEYNVYGPTECTVDATC
Nearest Stachelhaus code(s):: Gln or Glu DAQDLGVVDK (85% 8Å match); Ile DAQDLGVVDK (82% 8Å match); Gln DAQDLGVVDK (76% 8Å match)
Stachelhaus code match:: 90% (moderate)

Link to PARAS substrate predictor

TFBS definitions

Regulator	Description
AbrC3	Antibiotic production activator
LexA variant 3	Repressor of DNA damage response
SypG	Regulator of biofilm formation and host colonization

NZ_QNUC01000007.1 - Region 1 - NRP-metallophore,NRPS,t3nrps-iterative

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Location: 43,733 - 98,530 nt. (total: 54,798 nt) Show pHMM detection rules used

t3nrps-iterative: (AMP-binding and PP-binding and (DUF98 or Orn_Arg_deC_N or Orn_DAP_Arg_deC) and not ATP-grasp)
NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX) and not alpha_am_amid)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

NRPS/PKS modules

NRPS/PKS domains

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Oxidoreductases: dehydrogenase oxygenase

DN396_RS05820: Antibiotic biosynthesis monooxygenase

smcogs: SMCOG1258: Antibiotic biosynthesis monooxygenase

DN396_RS05900: short-chain dehydrogenase/reductase SDR

smcogs: SMCOG1001: short-chain dehydrogenase/reductase SDR

DN396_RS05960: aldehyde dehydrogenase

smcogs: SMCOG1017: aldehyde dehydrogenase

DN396_RS05965: 3-hydroxyisobutyrate dehydrogenase

smcogs: SMCOG1100: 3-hydroxyisobutyrate dehydrogenase

DN396_RS05970: acyl-CoA dehydrogenase

smcogs: SMCOG1006: acyl-CoA dehydrogenase

Transferases: PPTase

DN396_RS05865: 4'-phosphopantetheinyl transferase

smcogs: SMCOG1012: 4'-phosphopantetheinyl transferase

Hydrolases: hydrolase protease

DN396_RS05840: alkaline serine protease, subtilase family

smcogs: SMCOG1075: alkaline serine protease, subtilase family

DN396_RS05885: isochorismatase

smcogs: SMCOG1027: isochorismatase

Lyases: hydratase

DN396_RS05945: enoyl-CoA hydratase

smcogs: SMCOG1023: enoyl-CoA hydratase

Isomerases: isomerase

DN396_RS05895: isochorismate synthase

smcogs: SMCOG1018: isochorismate synthase

Ligases: ligase synthase

DN396_RS05815: Pseudouridine synthase

smcogs: SMCOG1154: Pseudouridine synthase

DN396_RS05880: condensation domain-containing protein

smcogs: SMCOG1127: condensation domain-containing protein

DN396_RS05890: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.5	1.57	NRPS	bacillibactin	Bacillus velezensis FZB42
BGC0000309.5	1.35	NRPS	bacillibactin	Bacillus subtilis subsp. subtilis str. 168
BGC0000401.5	1.29	NRPS	paenibactin	Paenibacillus elgii B69
BGC0002075.3	1.28	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0000343.5	1.28	NRPS	enterobactin	Pseudomonas sp. J465
BGC0001132.4	1.15	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.4	1.13	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	1.12	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001128.4	1.11	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286.3	1.08	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Reference	Similarity score	Type	Compound(s)	Organism
BGC0001185.5	0.80	NRPS	bacillibactin	Bacillus velezensis FZB42
BGC0000309.5	0.75	NRPS	bacillibactin	Bacillus subtilis subsp. subtilis str. 168
BGC0000401.5	0.74	NRPS	paenibactin	Paenibacillus elgii B69
BGC0002075.3	0.74	NRPS	pyreudione A, pyreudione B, pyreudione C, pyreudione D, pyreudione E	Pseudomonas fluorescens
BGC0000343.5	0.74	NRPS	enterobactin	Pseudomonas sp. J465
BGC0001132.4	0.71	NRPS	xenotetrapeptide	Xenorhabdus nematophila ATCC 19061
BGC0001833.4	0.70	NRPS	icosalide A, icosalide B	Burkholderia gladioli
BGC0001825.4	0.70	NRPS	xenematide	Xenorhabdus nematophila AN6/1
BGC0001128.4	0.70	NRPS	gamexpeptide C	Photorhabdus laumondii subsp. laumondii TTO1
BGC0002286.3	0.69	NRPS	ririwpeptide A, ririwpeptide B, ririwpeptide C	Photorhabdus laumondii subsp. laumondii TTO1

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 23.27 out of 27.55

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 27.77 out of 29.38

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 29.38 out of 29.38

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 26.61 out of 29.38

Confidence: strong

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 25.19 out of 30.25

Confidence: medium

MogR

Description: Repressor of flagellar motility genes
Species: Listeria monocytogenes EGD-e
Score: 23.67 out of 26.06

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.40 out of 29.38

Confidence: medium

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 25.11 out of 29.38

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.83 out of 27.78

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.76 out of 29.38

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 24.13 out of 27.78

Confidence: strong

CcpA

Description: Catabolite control protein A
Species: Streptococcus & Clostridium sp.
Score: 18.71 out of 20.97

Confidence: medium

CodY

Description: Regulator of stationary phase and virulence in Gram-positive bacteria
Species: Bacillus, Lactococcus & Streptococcus sp.
Score: 23.71 out of 27.78

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.98 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.53 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.75 out of 28.19

Confidence: medium

LexA variant 3

Description: Repressor of DNA damage response
Species: Escherichia coli str. K-12 substr. MG1655
Score: 26.20 out of 32.93

Confidence: medium

CatR

Description: H2O2-responsive repressor
Species: Streptomyces coelicolor
Score: 20.57 out of 25.31

Confidence: medium

Additional weak hits (6):

HipB

Description: Bacterial antitoxin HipB
Species: Escherichia coli BL21(DE3)
Score: 24.87 out of 33.73

Confidence: weak

ColR

Description: Phenol-responsive regulator
Species: Pseudomonas putida KT2440
Score: 22.54 out of 30.25

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 22.67 out of 32.74

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 25.52 out of 32.74

Confidence: weak

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 22.92 out of 29.38

Confidence: weak

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 24.90 out of 36.54

Confidence: weak

Module view

Legend

Detailed domain annotation

Selected features only

Show module domains

NRPS/PKS products

NRPS/PKS substrates

TFBS Finder

Predicted core structure(s)

For candidate cluster 1, location 43732 - 98530:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

DN396_RS05880: Gly - Thr

Search NORINE for peptide: strict or relaxed

AMP-binding (464..864): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: FAMTFDISALELQALVGGESNLYGPTETTIWSTV
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (97% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1524..1937): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: LATHFDFSVWEGNQVFGGEINMYGITETTVHVSY
Nearest Stachelhaus code(s):: Thr DFWNVGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

DN396_RS05890: diOH-Bz

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: SVSLYPMSSPGGALQVGGAQQVFGMAEGLVNYTR
Nearest Stachelhaus code(s):: diOH-Bz PMPAQGVVNK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

Link to PARAS substrate predictor

TFBS definitions

Regulator	Description
CatR	H2O2-responsive repressor
CcpA	Catabolite control protein A
CodY	Regulator of stationary phase and virulence in Gram-positive bacteria
ColR	Phenol-responsive regulator
FuR variant 1	Ferric Uptake Regulator
GnfM	Regulator of nitrogen-fixation genes
LexA variant 3	Repressor of DNA damage response
MogR	Repressor of flagellar motility genes
ZuR variant 1	Zinc-responsive repressor

NZ_QNUC01000008.1 - Region 1 - NI-siderophore

Download region GenBank file

Download region SVG

Location: 160,257 - 191,963 nt. (total: 31,707 nt) Show pHMM detection rules used

NI-siderophore: IucA_IucC

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

binding site

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Gene details

Select a gene to view the details available for it

Gene overview

Tailoring

MIBiG comparison

KnownClusterBlast

SubClusterBlast

TFBS Finder

Gene/CDS overview

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Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Tailoring functions

Transferases: aminotransferase

DN396_RS07380: aminotransferase

smcogs: SMCOG1019: aminotransferase

Hydrolases: deacetylase

DN396_RS07445: polysaccharide deacetylase

smcogs: SMCOG1235: polysaccharide deacetylase

Ligases: ligase synthase

DN396_RS07415: AMP-dependent synthetase and ligase

smcogs: SMCOG1002: AMP-dependent synthetase and ligase

DN396_RS07485: cysteine synthase

smcogs: SMCOG1081: cysteine synthase

Similar gene clusters

Analysis type:

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000942.4	0.88	other (other)	petrobactin	Bacillus anthracis str. Ames
BGC0002469.2	0.54	other (other)	woodybactin A, woodybactin B, woodybactin C, woodybactin D	Shewanella woodyi ATCC 51908
BGC0000295.5	0.51	NRPS	acinetoferrin	Acinetobacter haemolyticus
BGC0001478.5	0.51	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.3	0.50	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002692.2	0.50	other (other)	speibonoxamine, desoxy-desferrioxamine D1, desferrioxamine D1, desferrioxamine B, didesoxy-desferrioxamine D1, desoxy-desferrioxamine B, didesoxy-desferrioxamine B	Kribbella speibonae
BGC0001531.5	0.50	other (other)	bisucaberin B	Tenacibaculum mesophilum
BGC0002464.3	0.47	other (other)	alcaligin	Bordetella pertussis Tohama I
BGC0001498.5	0.46	other (other)	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0002683.2	0.46	NRPS	schizokinen	Nostoc sp. PCC 7120 = FACHB-418

Reference	Similarity score	Type	Compound(s)	Organism
BGC0000942.4	0.88	other (other)	petrobactin	Bacillus anthracis str. Ames
BGC0002469.2	0.54	other (other)	woodybactin A, woodybactin B, woodybactin C, woodybactin D	Shewanella woodyi ATCC 51908
BGC0000295.5	0.51	NRPS	acinetoferrin	Acinetobacter haemolyticus
BGC0001478.5	0.51	other (other)	desferrioxamine E	Streptomyces sp. ID38640
BGC0000941.3	0.50	other (other)	desferrioxamin B	Streptomyces griseus subsp. griseus NBRC 13350
BGC0002692.2	0.50	other (other)	speibonoxamine, desoxy-desferrioxamine D1, desferrioxamine D1, desferrioxamine B, didesoxy-desferrioxamine D1, desoxy-desferrioxamine B, didesoxy-desferrioxamine B	Kribbella speibonae
BGC0001531.5	0.50	other (other)	bisucaberin B	Tenacibaculum mesophilum
BGC0002464.3	0.47	other (other)	alcaligin	Bordetella pertussis Tohama I
BGC0001498.5	0.46	other (other)	aerobactin	Xenorhabdus szentirmaii DSM 16338
BGC0002683.2	0.46	NRPS	schizokinen	Nostoc sp. PCC 7120 = FACHB-418

Similar known clusters from MIBiG 4.0

Similar subclusters

No significant matches found.

Transcription Factor Binding Sites

Binding sites found:

ToxT

Description: Regulator of MSHA biosynthesis
Species: Vibrio cholerae O395
Score: 18.57 out of 18.57

Confidence: strong

GnfM

Description: Regulator of nitrogen-fixation genes
Species: Geobacter sulfurreducens PCA
Score: 23.16 out of 27.55

Confidence: medium

AbrC3

Description: Antibiotic production activator
Species: Streptomyces coelicolor
Score: 15.13 out of 18.16

Confidence: strong

FuR variant 1

Description: Ferric Uptake Regulator
Species: Bacillus, Pseudomonas, Yersinia sp.
Score: 24.38 out of 29.38

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.40 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 23.93 out of 28.19

Confidence: medium

ZuR variant 1

Description: Zinc-responsive repressor
Species: Streptomyces coelicolor
Score: 22.11 out of 28.19

Confidence: medium

Additional weak hits (4):

HgtR

Description: Hydrogen-dependent regulator
Species: Geobacter sulfurreducens PCA
Score: 25.60 out of 36.54

Confidence: weak

FuR variant 2

Description: Ferric Uptake Regulator
Species: Caulobacter crescentus CB15
Score: 23.50 out of 32.74

Confidence: weak

HypR

Description: L-hydroxyproline utilization repressor
Species: Streptomyces coelicolor
Score: 18.94 out of 22.40

Confidence: weak

AfsQ1

Description: Two-component system AfsQ1-Q2, activator of antibiotic production
Species: Streptomyces coelicolor
Score: 16.58 out of 19.52

Confidence: weak

TFBS Finder

TFBS definitions

Regulator	Description
AbrC3	Antibiotic production activator
FuR variant 1	Ferric Uptake Regulator
GnfM	Regulator of nitrogen-fixation genes
ToxT	Regulator of MSHA biosynthesis
ZuR variant 1	Zinc-responsive repressor