LOCUS       NZ_RDBM01000037        21032 bp    DNA     linear   CON 01-JAN-2025
DEFINITION  Streptomyces sp. gb1(2016) Scaffold_37, whole genome shotgun
            sequence.
ACCESSION   NZ_RDBM01000037
VERSION     NZ_RDBM01000037.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. gb1(2016)
  ORGANISM  Streptomyces sp. gb1(2016)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 3233341)
  AUTHORS   Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K.,
            Campbell,A.N. and Buckley,D.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University,
            306 Tower Road, Ithaca, NY 14850, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: A5+MeDuSa v. JUNE-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008042065.1-RS_2025_01_01
            Annotation Date                   :: 01/01/2025 02:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,414
            CDSs (total)                      :: 7,333
            Genes (coding)                    :: 6,887
            CDSs (with protein)               :: 6,887
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 447
            CDSs (without protein)            :: 446
            Pseudo Genes (ambiguous residues) :: 0 of 447
            Pseudo Genes (frameshifted)       :: 94 of 447
            Pseudo Genes (incomplete)         :: 395 of 447
            Pseudo Genes (internal stop)      :: 7 of 447
            Pseudo Genes (multiple problems)  :: 48 of 447
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:17:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1726049
            Orig. end                         :: 1747081
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RDBM01000037.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..21032
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="3"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..21032
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..21032
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:11032](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..11032)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     gene            complement(202..1002)
                     /gene="yaaA"
                     /locus_tag="EAO74_RS29330"
                     /old_locus_tag="EAO74_29350"
     CDS             complement(202..1002)
                     /codon_start=1
                     /gene="yaaA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969487.1"
                     /locus_tag="EAO74_RS29330"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29350"
                     /product="peroxide stress protein YaaA"
                     /protein_id="WP_124276756.1"
                     /transl_table=11
                     /translation="MLVLLPPSEGKAASGRGAPLKPESLSLPGLADARAAILDELVELC
                     LADEEKAREVLGLSEGLRGEIAKNAELRTAGTRPAGEIYTGVLYDALGLATLDTAAKRR
                     AGQSLLVFSGLWGAVRVGDRIPSYRCSMGVKLPGLGALNAHWRAPMASVMPEAAGDGLV
                     LDLRSSAYAAAWKPSGEVAERTASVRVLQSRMVDGVEKRSVVSHFNKATKGRMVRDLLV
                     AGARPKGPAELVEVLRDLGHVVEAKAPERAGRPWALDVVVTEIH"
     gene            1135..2574
                     /locus_tag="EAO74_RS29335"
                     /old_locus_tag="EAO74_29355"
     CDS             1135..2574
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /GO_function="GO:0004540 - RNA nuclease activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018511775.1"
                     /locus_tag="EAO74_RS29335"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29355"
                     /product="RNB domain-containing ribonuclease"
                     /protein_id="WP_147985250.1"
                     /transl_table=11
                     /translation="MPRRHLHLTGADGTPLRSALHTLRTGLGLPAGFPPAVLAEAVEAA
                     RTPDVSGHLDATDLPFLTIDPPGSTDLDQAMYLERRPHGFRVLYAIADVAAFVRPGGEP
                     DAEAHRRVTTLYFPDGRIPLHPPVLSEGAASLLPGETRPAALWRIDLDTEGRTVAAEVR
                     RALVRSRAQLDYAGVQRQIDAGTAEEPLALLRVIGLLRQQQETARGGISLDVPEQEIVA
                     RGGTYGLEYRAPVPAESWNAQISLLTGMAAAALMRDSGTGILRTLPVAPDGAVARLRRS
                     AEALRIDWPHHVPYAEVVRSLDPAKGSHAAFLQECTTLLRGAGYSVFTHGDLPVPAVHA
                     AVAELYTHCTAPLRRLVDRYAAELCLAATAEREPPEWVLRALPGLPAEMAEGTRRANTV
                     ERACVDLVEAALLGDRIGEVFDGYVIDVKDGEPGIGTVHIEDPAIVARIESSTPLPLGE
                     RLRARLTRADLGSSKVLFAPA"
     gene            2716..3249
                     /locus_tag="EAO74_RS29340"
                     /old_locus_tag="EAO74_29360"
     CDS             2716..3249
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1239: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156543.1"
                     /locus_tag="EAO74_RS29340"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29360"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_147985251.1"
                     /transl_table=11
                     /translation="MTDLATAPATGRPRQIVAAARALLEAEGPEALTMRRLADRVGVTA
                     PSLYKHFPDKSSVVEALADEMLRETAGVLEAAEAAAPGSFSALATAYRAYALAHPHLYL
                     LTMGRPLPAAGPAAAASAPLFRAAGGDEDRARAAWAFAHGMVVLELNGRFPPGADLSAA
                     WEAGVAAFTPGPAG"
     ncRNA           3268..3667
                     /db_xref="RFAM:RF00010"
                     /gene="rnpB"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /locus_tag="EAO74_RS29345"
                     /ncRNA_class="RNase_P_RNA"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /old_locus_tag="EAO74_29365"
                     /product="RNase P RNA component class A"
     gene            3268..3667
                     /gene="rnpB"
                     /locus_tag="EAO74_RS29345"
                     /old_locus_tag="EAO74_29365"
     misc_feature    complement(3370..3382)
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 18.92"
                     /tool="antismash"
     gene            3872..5353
                     /locus_tag="EAO74_RS29350"
                     /old_locus_tag="EAO74_29370"
     CDS             3872..5353
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1169: sugar
                     transport protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534595.1"
                     /locus_tag="EAO74_RS29350"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29370"
                     /product="MFS transporter"
                     /protein_id="WP_124276760.1"
                     /transl_table=11
                     /translation="MSSTSPLPAGTSPATAPGTVLIRSAADVSDLVNSGTARGSHAKMI
                     VIIALGGIFLDAYDLSSLAYGLPDITRQFGLSSAMAGTVIASISVGSLIGALVGGWLVD
                     RIGRYRVFMANMLFFVVTALVCALAQDVWTLIAARFVMGIGVGMDIPVAIAFLAEFSRL
                     RGKGSKGSRTAAWSPAWYTATSGCYLVIMLLYFVLPDAQLGWLWRFTVGFGAVPAVIVL
                     LLRRRYMNESPTWAADQGDLASAAKILRQSYGVDARVADDVPATAPRPPRPGLASYARL
                     FAPPYRARTVQSVTVGVAETFGYNAVAFGLPIIIATLMTQGPLTTIASSFALNLVFALT
                     GGLLGIRWASTRGAWPMMTLGFAIQFVAITVLGLIGDPSGTAYVTGGILMLGAFMFAQG
                     FGPGAHIMSYASLGFPTSMRGVSIGFNQAVLRLGSTLTLFFFPILSSGLGTHVYWVILA
                     APVLGLIALLVKRWEPVGFDADAEERELSGAASRG"
     gene            5623..7311
                     /locus_tag="EAO74_RS29355"
                     /old_locus_tag="EAO74_29375"
     CDS             5623..7311
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576969.1"
                     /locus_tag="EAO74_RS29355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29375"
                     /product="ATP-binding protein"
                     /protein_id="WP_147985252.1"
                     /transl_table=11
                     /translation="MELATPPPAARAPVAWYGWWLMPLALGAGTVATAVAGPDQVQIPA
                     TFAGAAVTVAGAACVRLLVRSRSQLRRANDDFRAAQAEQSQQRYAEVRGREQRFAAERS
                     ALEAQLGEQAALFEARLAEHTQAYEAGIAERARATEERIALQQAVVVRLGDSYLPEAVA
                     RLRDGEAIDDILAEAGQEGDASPELRAALRKVLRTALLSVEEELNRSTSAEQAVVGIGS
                     RIHVLTGRLRGRLHEMQGEHGRLPAVAQGLMELDQEIGPADCLAASIGVLGGSDRPGRQ
                     WQEPQRLLSVVRGGIGRIKDFNRIQVRHLPELGVDGGLVDHLTLIFAHLLDNAARYSPP
                     TEPVVVSGKEVPNGVGIEIQDAGKGLTDERKREAEQSIAGTSKGPGLGGISEDANLGLR
                     VVGALARRYGIRVTFADSPWLGTSVVVVVPHKYFSHLPAPVTEPARPAVERAEPVPEPA
                     VAAAPVAAAPVESTEAIDTMDTTPGGLPRRRSRRADAPTARPAGADRTAESMAAVPPDA
                     SFAGLAAFATAGRESGPPGGTDADAAPGARETTAGRESNRTEESD"
     misc_feature    5698..5700
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
     gene            7317..7727
                     /locus_tag="EAO74_RS29360"
                     /old_locus_tag="EAO74_29380"
     CDS             7317..7727
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019057749.1"
                     /locus_tag="EAO74_RS29360"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29380"
                     /product="roadblock/LC7 domain-containing protein"
                     /protein_id="WP_099172315.1"
                     /transl_table=11
                     /translation="MTQQGTDVSWALRDLTESIREIRFALVASSDGKAITSYGADDPDD
                     VDRFAAVVAGLQALAQPVAEQFPTYAGQLRLAMIEVDGGHLFVVRAGVETYLGVLAREG
                     LDQGLLGHQMRDLARRMGELLGTSPRLEEQPG"
     gene            7724..8095
                     /locus_tag="EAO74_RS29365"
                     /old_locus_tag="EAO74_29385"
     CDS             7724..8095
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003995719.1"
                     /locus_tag="EAO74_RS29365"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29385"
                     /product="DUF742 domain-containing protein"
                     /protein_id="WP_031096986.1"
                     /transl_table=11
                     /translation="MSGPRRPTDPPGLERYYVLTGGRSGPGGSASTLDVATLIISRAAA
                     EPGLQHEHEEILRRCRDPLSVAELGAHLGLPFNILAVLLADLLDAGRVEARDPIPASGA
                     GRGPDLALLEEVLSGLQRL"
     gene            8076..8684
                     /locus_tag="EAO74_RS29370"
                     /old_locus_tag="EAO74_29390"
     CDS             8076..8684
                     /EC_number="3.6.5.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156547.1"
                     /locus_tag="EAO74_RS29370"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29390"
                     /product="GTP-binding protein"
                     /protein_id="WP_099172314.1"
                     /transl_table=11
                     /translation="MDFKGFDHPDRQTAGGGTRSVKVMIAGGFGTGKTTLVRSVSDIKP
                     LTTEETLTQASVDVDDLIGVADKQQTTVSLDFGKIGINEELVLYLFGTPGQERFWFLWN
                     GLFKGALGAVVLVDTRRLASSFRAIEEMERQDVPFVIALNVFPDSKDHPVEEIRDALDI
                     PEHTPVVTCDARDRNSSRDVLIALIRHLKARSAVALEPR"
     gene            8681..9934
                     /locus_tag="EAO74_RS29375"
                     /old_locus_tag="EAO74_29395"
     CDS             8681..9934
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015655858.1"
                     /locus_tag="EAO74_RS29375"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29395"
                     /product="cytochrome P450"
                     /protein_id="WP_124276762.1"
                     /sec_met_domain="p450 (E-value: 1.4e-05, bitscore: 21.5,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDHPADEEGAPRGCPVMHGGADDLTRLYGPDAAVDPQGIYGRLR
                     KEYGAVAPVLLEGDVRAWLVLGYRESRRVLDNPLQFSRDSRIWRDWQEGGVEETSPLIQ
                     MLGWRPDCVSQDGEPHRRLRRAVTDNLDTLAGRGIRRHVTHFANKQIDAFAGRGSADLV
                     GEYAEYLPMLVLTRLFGLPAAEGRSLAAACAQVLKGGPDALAHNDRIMEILGELAERKR
                     LEPGPDFTTGLLGHTAGLDEGEIVSHLRLVLITAHTTTSNLLARVLELILTDASRLAGL
                     VSGQRAVSEVVEEVMWNTPPLAVLPGRFATADLELGGTQIKEGDLLVLGLAAGNLDPDI
                     RPDSGVSVHGNQSHLAFSGGPHECPGQNIGQAIIETAVDTLLHRLPGLRLAVPADELTS
                     TASTWEARLDALPVEFAA"
     gene            complement(10001..11032)
                     /locus_tag="EAO74_RS29380"
                     /old_locus_tag="EAO74_29400"
     CDS             complement(10001..11032)
                     /EC_number="4.2.3.169"
                     /GO_function="GO:0016829 - lyase activity [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T1TS"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052: Terpene synthase/cyclase metal-binding domain
                     protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010040594.1"
                     /locus_tag="EAO74_RS29380"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29400"
                     /product="7-epi-alpha-eudesmol synthase"
                     /protein_id="WP_124276763.1"
                     /sec_met_domain="T1TS (E-value: 1.7e-70, bitscore: 236.1,
                     seeds: 237, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPQDVTFDLPFETPVSAHLAYAREHHLRWVWEMGLVRSQAGFEEY
                     QSWDLPQAAARTYPYASAEDMVVLMNWFSLAFLFDDQFDSGSPDRADRIAEVARELIAT
                     PLRPAGTAPRVVCPITVAWAQVWAHLSDGMSLTWQTRFAASWGRFLVAHTEEVDLAAEG
                     RAGTLGVEEYAEFRRRTVGIHHSIDAGERSRGFEVPAQVQAHPLMVRMRDLAADTIGFM
                     NDIHSFEREKRRGDGHNLIAVLHRERGCTWEEAAAEAYRMTTVCLDEYLALEALVPRMC
                     EELGLGAEQREQVRLGVEAIQHWIGGNYEWALTSGRYAAAKEGPAATAELAGRGSLDDL
                     LAV"
     misc_feature    11117..11130
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.06"
                     /tool="antismash"
     misc_feature    complement(11118..11131)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.99"
                     /tool="antismash"
     gene            complement(11342..12109)
                     /locus_tag="EAO74_RS29385"
                     /old_locus_tag="EAO74_29405"
     CDS             complement(11342..12109)
                     /NRPS_PKS="Domain: Abhydrolase_1 (25-128). E-value:
                     6.9e-24. Score: 76.7. Matches aSDomain:
                     nrpspksdomains_EAO74_RS29385_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abhydrolase_6"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1262: haloalkane dehalogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003989977.1"
                     /locus_tag="EAO74_RS29385"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29405"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_147985253.1"
                     /sec_met_domain="PF00561 (E-value: 4e-19, bitscore: 66.7,
                     seeds: 48, tool: rule-based-clusters)"
                     /sec_met_domain="Abhydrolase_6 (E-value: 1.2e-12, bitscore:
                     46.4, seeds: 455, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRDAVVTAEGDRIRWAELPGREPTRVYVHGLGATSPAYFAATASH
                     PALAGHRSLLVDLMGHGISDRPTGFDYTLESHADALAAALREAGVTGAEVIAHSMGGSV
                     ALVLAARHPHLVSRLVLADANLDPVTPAVGAPGSAGIAAYTEQEFLQGGWEQVRDRAGA
                     HWWATMRLAGREALYRSAVHLARGTSPVMRELLLRLTIPRAFLFPEADGPLAGAGELRS
                     AGVLVVPVPDCGHNIMLDNPEAFVRATAAALSG"
     aSDomain        complement(11726..12034)
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EAO74_RS29385_Abhydrolase_1.1"
                     /evalue="6.90E-24"
                     /label="EAO74_RS29385_Abhydrolase_1.1"
                     /locus_tag="EAO74_RS29385"
                     /protein_end="128"
                     /protein_start="25"
                     /score="76.7"
                     /tool="antismash"
                     /translation="VYVHGLGATSPAYFAATASHPALAGHRSLLVDLMGHGISDRPTGF
                     DYTLESHADALAAALREAGVTGAEVIAHSMGGSVALVLAARHPHLVSRLVLADANLDP"
     gene            complement(12182..12610)
                     /locus_tag="EAO74_RS29390"
                     /old_locus_tag="EAO74_29410"
     CDS             complement(12182..12610)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004986724.1"
                     /locus_tag="EAO74_RS29390"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29410"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_124276765.1"
                     /transl_table=11
                     /translation="MALTRTERELFLAEPHIAALAVDAPEEGRAPLTVPIWYQYAPGGD
                     LWVMTGRDSRKGTAIAAAGRFSIMVERVSPTIRYVSVEGPVVATLPATREQLVEISSRY
                     LPAEKVAGYVDFAWKEHGEQVVIHMRPQRWLSSDLGQV"
     misc_feature    12651..12663
                     /note="TFBS match to LuxO, Repressor of luminescence,
                     confidence: weak, score: 19.13"
                     /tool="antismash"
     gene            12783..13304
                     /locus_tag="EAO74_RS29395"
                     /old_locus_tag="EAO74_29415"
     CDS             12783..13304
                     /EC_number="2.3.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156551.1"
                     /locus_tag="EAO74_RS29395"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29415"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_147985254.1"
                     /transl_table=11
                     /translation="MAQDTSVRLREATAGDAEEVTRVYLASRAAALPYLPRVHSDADTL
                     AWITHVLLPGGRTWVAEGEAGELLGFASLDGDELDQLYLRPDVRRRGIGTLLLERAKEA
                     SRGELSLYTFRRNAAARAFYERHGFVAEAYDDGGRNEEKEPDVLYRWTAAGLPADSSDS
                     SGSRGTAGAV"
     gene            complement(13353..14255)
                     /locus_tag="EAO74_RS29400"
                     /old_locus_tag="EAO74_29420"
     CDS             complement(13353..14255)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018958206.1"
                     /locus_tag="EAO74_RS29400"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29420"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_147985255.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.2e-09,
                     bitscore: 35.8, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSEPRIGVSVVTMGDRPQQVEALLASVAMQDVRPARVVVVGNGSP
                     LPDYGSFPGLEDLSGGVTVLELDENLGCPGGRNEALEELAGFGDVDVVIELDDDGLLVD
                     KDVFRTVQELYAADPDLGIVGFRIADEHGETQRRHVPRLRAKDPMRPGPVTAFLGGGHA
                     LSMRMLAETGPWPAEFFFTHEETDLSWRALDAGWKILYEPRLLLQHPRTSPARHAVYYR
                     MTARNRVWLARRNLPLPLVPAYLGTWILLTAARTRSASGLRAWGAGFAEGVRTECGERK
                     PMRWRTVWRMTRLGRPPVI"
     gene            complement(14334..14915)
                     /locus_tag="EAO74_RS29405"
                     /old_locus_tag="EAO74_29425"
     CDS             complement(14334..14915)
                     /EC_number="2.3.-.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016746 - acyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1111: GCN5-related N-acetyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576964.1"
                     /locus_tag="EAO74_RS29405"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29425"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_147985256.1"
                     /transl_table=11
                     /translation="MAQPLTVPSMTAGADFVLRPWEMSDLPLVREAAQDDYIPLVTTIP
                     SPYSDEAAEAYVRRQWERAARGEGYPFAIARTRDRRPVGSIGLWLTDVAQGRATLGYWM
                     TAPVRGQGVAGAALRTVTTWALHELRIPRVQLLVEPCNTASVRTAESAGYRREGLMRGW
                     QEIGGRRRDMLMYAQLNGDRPSGDRAPTGA"
     gene            15131..15757
                     /locus_tag="EAO74_RS29410"
                     /old_locus_tag="EAO74_29430"
     CDS             15131..15757
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015035782.1"
                     /locus_tag="EAO74_RS29410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29430"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_124276769.1"
                     /transl_table=11
                     /translation="MEPAAGDAVDVEPGTVRPGGRTARVREAVLRAAGDALVEQGFDRL
                     DLADVARRAEVGKTTVYRRWSTAAGLVADLLTEMAEQSVPRADTGSLDEDLRSNARLVV
                     RTLTDPRQGPLFTAVVAAATCDARTAGALHRFYAVRIEEWAGCVDAAVARGDLPPGTDA
                     REVIRAVSAPLYYRLLASGDPLDETVADRAAEAAAVAARAGVYVR"
     gene            15814..16812
                     /locus_tag="EAO74_RS29415"
                     /old_locus_tag="EAO74_29435"
     CDS             15814..16812
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016616 - oxidoreductase activity, acting
                     on the CH-OH group of donors, NAD or NADP as acceptor
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1039: aldo/keto reductase family oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156556.1"
                     /locus_tag="EAO74_RS29415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29435"
                     /product="aldo/keto reductase"
                     /protein_id="WP_147985257.1"
                     /transl_table=11
                     /translation="MQTDMDRRKRTQDRGGFEAGALGFGCWAIGGEWSAPDGSPLGWGT
                     VDDDESVAAVRRALDLGVTFFDTADVYGAGHSERVLGRALAGRRDEAVIATKWGNLFDE
                     RTRTMDGADTSPAYARQALVASLRRLGTDRIDLYQLHLGDTPLDEAAELRDACEEFVAE
                     GLIRAYGWSTDDPERAALFADGEHCAAVQHACNVLEDAPGMLNLSEERGLFSVIRSPLA
                     MGLLTGARDPGRRAAAGDIRSTPPAWLSWYEQGGVPARHWAARVEAVREVLTADGRTLA
                     QGALGWLWARSGRAVPIPGFRTVAQAEENAAALTHGPLRPAQLEEVAALLA"
     gene            complement(16863..17660)
                     /locus_tag="EAO74_RS29420"
                     /old_locus_tag="EAO74_29440"
     CDS             complement(16863..17660)
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1292: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015576961.1"
                     /locus_tag="EAO74_RS29420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29440"
                     /product="SAM-dependent methyltransferase"
                     /protein_id="WP_124276771.1"
                     /transl_table=11
                     /translation="MTSIEIDTTKPHPARLYDWYLGGKDNYPVDEELGRRLTAFAPVIP
                     VMARMNRAFTHRATRWLAGQGIRQFLDIGTGIPTEPNLHQVAQTTVPDARVVYCDNDPV
                     VLSHAQALLNGSDEGALGYVQADARETDRILAEAAGVLDLGRPVALSLNALLHFLSDEM
                     GAYEVVEQLTAALAPGSYLVISHLTPDFHPEEASQKVRDMYKANGLTLDMRDRDRFTRF
                     FDGLDLVAPGVVAAEEWHPELGEPVPGQESAHSGEYVAVARKA"
     gene            complement(17774..18628)
                     /locus_tag="EAO74_RS29425"
                     /old_locus_tag="EAO74_29445"
     CDS             complement(17774..18628)
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014156558.1"
                     /locus_tag="EAO74_RS29425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29445"
                     /product="PhzF family phenazine biosynthesis protein"
                     /protein_id="WP_147985258.1"
                     /transl_table=11
                     /translation="MSTHTDSEVLRYTAFSADPEGGNPAGVVLDASGLDDAAMLAVAAE
                     LGYSESAFLTASDGRGGHTVRYFSPKAEVPFCGHATVATALALAERDGPGDLVFSTLAG
                     QVPVTVVREDGELRATLTSVEPHTEDAAPEDVAEALAALDWPAADLDPALPPRIAYAGA
                     RHLVLAAATRERLADLSYDFARLEALMQRLGLTTVQLVWRESATVFHVRXPFPVGGVVE
                     DPTTGAAAAAFGAYARELGLVPHDAVLTLHQGADMGRPGTLTVGLRTGDPRVRVTGTGT
                     RIG"
     gene            complement(18778..19242)
                     /locus_tag="EAO74_RS29430"
                     /old_locus_tag="EAO74_29450"
     CDS             complement(18778..19242)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003969495.1"
                     /locus_tag="EAO74_RS29430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29450"
                     /product="lamin tail domain-containing protein"
                     /protein_id="WP_099172302.1"
                     /transl_table=11
                     /translation="MRIRTAAPLALAAATALAGSLLASVPASAASHQGGLHLGKIQYDS
                     PGKDTRTNTSLVAEYVDIHNNGKSKLQLKGYKLKDNTGYTYTFPSFSIAAGKTVRVHTG
                     KGKNSAAHVYWNRGSYVWNNTGDKARLIKPSGALLDSCSWGKGTGVKVCH"
     misc_feature    19232..19245
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.91"
                     /tool="antismash"
     gene            complement(19400..20155)
                     /locus_tag="EAO74_RS29435"
                     /old_locus_tag="EAO74_29455"
     CDS             complement(19400..20155)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (8-173). E-value: 2e-10. Score:
                     32.8. Matches aSDomain:
                     nrpspksdomains_EAO74_RS29435_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019765022.1"
                     /locus_tag="EAO74_RS29435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_29455"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_099172973.1"
                     /sec_met_domain="adh_short (E-value: 5.5e-33, bitscore:
                     111.9, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNAEQRIAVVTGAGSGIGRAVALTLTGAGWTVALAGRRAGALEET
                     AAAAGPGATVCLPTDVGDPDSVAALFASVRERFGRLDLLFNNAGTFGPGATPVEDLAYE
                     DWRTVVDVNLTGTFLCAQAAYRLMKEQDPQGGRIINNGSVSAHAPRPHSVAYTATKHAV
                     TGLTKSLSLDGRPYRIACGQIDIGNAATEMTERMSTGILQANGELAAEPVMAADDVART
                     VLHMAELPLEANVQFATVMATAMPYVGRG"
     aSDomain        complement(19637..20131)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EAO74_RS29435_PKS_KR.1"
                     /evalue="2.00E-10"
                     /label="EAO74_RS29435_PKS_KR.1"
                     /locus_tag="EAO74_RS29435"
                     /protein_end="173"
                     /protein_start="8"
                     /score="32.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVTGAGSGIGRAVALTLTGAGWTVALAGRRAGALEETAAAAGPGA
                     TVCLPTDVGDPDSVAALFASVRERFGRLDLLFNNAGTFGPGATPVEDLAYEDWRTVVDV
                     NLTGTFLCAQAAYRLMKEQDPQGGRIINNGSVSAHAPRPHSVAYTATKHAVTGLTKSLS
                     LD"
ORIGIN
        1 ggccagcggc accgcgtcgg ccgcgtcctc cagcacgacg acggggacga cgggggcgag
       61 gtccagcacg gaggtggaca cggcagcggg cacggaggag gtcatggaca catcctgccg
      121 cgagaaccgc acactgcgca acgcgcgttg cgcaggatgc aacgcagggt ctggggggct
      181 acgacccgac ggaccggccg atcagtggat ctcggtgacc accacgtcga gcgcccacgg
      241 ccgccccgcc cgctccgggg ccttcgcctc cacgacgtga ccgaggtcgc gcagcacctc
      301 caccagctcg gccggcccct tcggccgggc ccccgccacc agcagatcgc ggaccatccg
      361 gcccttcgtc gccttgttga agtggctgac cacggaccgc ttctccaccc cgtcgaccat
      421 ccgggactgg agcacccgca cgctcgccgt gcgctcggct acctcgcccg agggcttcca
      481 cgccgcggcg tacgcggacg agcgaaggtc caggaccagc ccgtccccgg ccgcctccgg
      541 catgaccgac gccatcggcg cgcgccagtg cgcgttcagc gcgcccagac ccggcagctt
      601 cacgcccatc gagcagcggt acgaggggat ccggtcgccc acccgcaccg cgccccacag
      661 cccggagaag accagcagcg actgcccggc ccgccgcttg gccgccgtgt ccagcgtggc
      721 cagaccgagc gcgtcgtaca gcaccccggt gtagatctcc ccggccggcc gggtgccggc
      781 cgtacgcagc tccgcgttct tcgcgatctc gccgcgcagc ccctcgctca ggcccagcac
      841 ctcacgggcc ttctcctcgt ccgccaggca cagctcgacc agctcgtcga ggatcgcggc
      901 cctggcgtcg gcgaggccag gcagggacag ggactccggc ttcagcggtg ccccgcgccc
      961 cgaggcggcc ttaccttcgg agggcggcaa cagcacgagc acgggcgttc tccttcatac
     1021 gcggcacagg gccccgcgta cacgggagcc ccggccaagg gtacgggcgc cggtccgccc
     1081 ggagccccgg agaccgggat gccgaccgca ccgccccggc ctacgctcga tggcatgccc
     1141 cgccgccacc tgcatctgac cggcgcggac ggaaccccgc tgcggtcggc cctgcacacc
     1201 ctgcgcaccg ggctcggcct gcccgccggc ttcccgcccg ccgtcctcgc cgaggcagtg
     1261 gaggcggcga gaaccccgga cgtctccggc cacctggacg ccacggacct gccgttcctc
     1321 accatcgacc cgcccggctc cacggacctc gaccaggcga tgtacctgga acggcgcccg
     1381 cacggcttcc gcgtgctcta cgccatcgcc gacgtcgccg ccttcgtccg ccccggcggc
     1441 gaaccggacg ccgaggccca ccgccgggtg acgaccctct acttccccga cggcaggatc
     1501 cccctgcacc ccccggtgct ctccgaggga gccgccagcc tcctcccggg cgagacccgg
     1561 cccgccgccc tctggcggat cgacctcgac acggagggcc gtacggtcgc cgccgaggtg
     1621 cgccgcgccc tcgtacgcag ccgcgcccag ctcgactacg cgggagtcca gcggcagatc
     1681 gacgcgggaa cggccgagga gcccctcgcc ctgctcaggg tcatcgggct gctgcgccaa
     1741 cagcaggaga ccgcccgggg cggcatctcg ctcgacgtac ccgagcagga gatcgtcgcg
     1801 cgcggcggca cctacggtct ggagtaccgc gcgcccgtgc ccgccgagag ctggaacgcc
     1861 cagatctccc tgctcaccgg tatggcggcc gccgcactca tgcgcgactc cggcaccggg
     1921 atcctccgta cgctgcccgt cgccccggac ggcgcggtcg cccggctcag acgctccgcc
     1981 gaggccctgc gcatcgactg gccgcaccac gtcccgtacg ccgaggtggt gcgctccctc
     2041 gacccggcca agggcagcca cgcggcgttc ctccaggagt gcaccacgct cctgcgcggc
     2101 gccggctaca gcgtcttcac ccacggcgac ctccccgtac ccgccgtgca cgccgccgtc
     2161 gccgagctct acacgcactg caccgcgccg ctgcgccgcc tcgtcgaccg ttacgccgcc
     2221 gaactgtgcc tggccgccac cgccgagcgg gagcccccgg agtgggtgct ccgggcgctg
     2281 cccggcctgc ccgcggagat ggccgagggc acccgccgcg ccaacaccgt ggagcgcgcg
     2341 tgcgtcgatc tcgtcgaggc ggcgctgctc ggggaccgga tcggcgaggt cttcgacggg
     2401 tacgtgatcg acgtcaagga cggcgagccc ggcatcggca ccgtccacat cgaggacccc
     2461 gcgatcgtcg cccggatcga gtcctccacc ccgctgcccc tgggcgaacg gctgcgggcc
     2521 cgcctcaccc gggccgacct cggctcctcg aaggtgctgt tcgcacccgc gtgaacccgg
     2581 nccgccggcc cccggcccag cacccgcgtg aaccccggtc cttcgccccc cggcgaccgg
     2641 cttgtccgta tctcgtacga tcacgtcctc ggctacggaa cgcgtagcga ctccgtacca
     2701 gggaaggtct cccgcgtgac tgacctcgcc accgccccag cgaccggccg gccccggcag
     2761 atcgtcgccg cggcacgcgc gctgctggag gcggagggcc ccgaggcgct caccatgcgc
     2821 cggctggcgg accgggtggg cgtcacggca ccgtccctgt acaagcactt cccggacaag
     2881 tcgtccgtgg tggaggcgct ggccgacgag atgctcaggg agacggccgg agtcctggag
     2941 gccgccgagg cggcggcccc gggctccttc tccgcactcg ccaccgccta ccgcgcctac
     3001 gccctggccc acccgcacct ctacctcctc accatgggcc ggccgctccc cgccgcgggn
     3061 cccgcggccg ccgcctcggc cccgctgttc cgggccgccg ggggcgacga ggaccgggcc
     3121 agggcggcct gggccttcgc ccacggcatg gtggtcctgg agctgaacgg ccgcttcccg
     3181 ccgggcgcgg acctctcggc cgcctgggag gcgggcgtcg cggccttcac ccccggaccc
     3241 gccgggtagc atggtcacca cggcagacga gccgggcgga cggccgcgtg aggatccccg
     3301 gatcctcccg aggaacgtcc gggctccaca gggcagggtg atggctaacg gccacccggg
     3361 gtgacccgcg ggacagtgcc acagaaaaca gaccgccggg gacttcggcc cccggtaagg
     3421 gtgaaacggt ggtgtaagag accaccagcg cctgaggcga ctcaggcggc taggtaaacc
     3481 ccacccggag caaggtcaag agggagcacc ccggtgctcc tgcgcgaacg tccgagggct
     3541 gcccgcccga gttcgcgggt agaccgcacg agaccggcag caatgccggt cctagatgga
     3601 tggccgtctc cccggccgcc gcgaggcgac cgggcgacag aacccggcgt acagcccgac
     3661 tcgtctgccg cccccaggtc cccgaccagc gaaaatgctg ggcagggggc ttttttcggt
     3721 ttacccacgc tttgtgcgcg tgatcccggc cgcatcgtga ccatcatgcg gacaagctga
     3781 agaacacatt ccgcttggtg tctacgatcc gtcgggacgt cccccaccgt cctccggtcc
     3841 cacagtcccc gcagcacacc agaaggcgct cgtgagctcc acctcccccc tccccgccgg
     3901 aacctccccg gcgacggccc cgggcacggt tctgatccgc tccgcggccg acgtctccga
     3961 ccttgtcaat tcgggtacgg cacgtggcag tcacgccaag atgatcgtga tcatcgcgct
     4021 cggcggcatc ttcctcgacg cctacgacct gagttccctc gcctacgggc tgcccgacat
     4081 cacccggcag ttcggcctca gctccgccat ggccggtacg gtcatcgcct cgatcagcgt
     4141 cggttcgctg atcggcgccc tcgtcggcgg gtggctggtc gaccggatcg gccgctaccg
     4201 ggtcttcatg gccaacatgc tcttcttcgt cgtcaccgcg ctggtgtgcg cgctggcgca
     4261 ggacgtgtgg acgctgatcg ccgcacgctt cgtgatgggc atcggcgtcg gtatggacat
     4321 cccggtcgcc atcgcgttcc tcgccgagtt ctcccggctg cgcggcaagg gcagcaaggg
     4381 ctcgcgcacg gccgcctggt cgcccgcctg gtacaccgcg accagtggct gctacctggt
     4441 gatcatgctg ctgtacttcg tgctgcccga cgcccagctg ggctggctgt ggcggttcac
     4501 cgtcggcttc ggcgccgtgc ccgcggtgat cgtcctgctg ctgcgccgcc gctacatgaa
     4561 cgagtccccg acctgggccg ccgaccaggg tgacctggcg agcgccgcga agatcctccg
     4621 gcagtcctac ggcgtggacg cccgcgtcgc cgacgacgtg cccgcgacgg cgccccgccc
     4681 gccccggccg ggcctcgcct cgtacgcccg gctcttcgcc ccgccctacc gtgcccgcac
     4741 ggtccagtcg gtgacggtcg gcgtggccga gaccttcggc tacaacgcgg tcgcgttcgg
     4801 gctgccgatc atcatcgcca ccctgatgac ccagggcccg ctgaccacga tcgcctcctc
     4861 cttcgcgctg aacctcgtct tcgccctgac cggtgggctg ctcggcatcc gctgggcgtc
     4921 gacccgcggt gcctggccga tgatgacgct gggcttcgcg atccagttcg tcgccatcac
     4981 ggtgctcggg ctcatcgggg acccgtccgg gacggcctac gtgacgggcg ggatcctgat
     5041 gctgggcgcg ttcatgttcg cccagggctt cggccccggc gcgcacatca tgagctacgc
     5101 ctcgctgggc ttcccgacct ccatgcgcgg ggtcagcatc ggcttcaacc aggccgtgct
     5161 gcgcctcggg tccacgctga ccctgttctt cttccccatc ctcagcagcg gcctgggcac
     5221 ccacgtctac tgggtcatcc tcgccgcccc tgttctcggc ctgatcgcgc tgctggtgaa
     5281 gcgctgggaa ccggtcggct tcgacgccga cgcggaggaa cgggagctgt ccggggcggc
     5341 ctccaggggc tgaccccctg gtcgtacgcg aggcgcgtca gccgtaccac acggcctgcc
     5401 gcgcctcgct gccgttacgg agaccggaag gttccggcca gacccgatca cgtacctgtc
     5461 ggtatgcgga ggggagttga tcacttctgc ctctgacccg ataggctcct ttgcggcgcg
     5521 gcgagttgac tcgaactcaa ccggccgccg ccgcgctgcc cgctcggcgt gtgcggcgcc
     5581 ccgcgacccc ctgttcgatt gtgttgctct cgaaggatgc agatggaact tgccactcca
     5641 cccccggcgg cacgtgctcc ggtcgcctgg tacggctggt ggctgatgcc gctggcctta
     5701 ggagccggaa ccgtcgccac cgcagtggcg ggacctgatc aggtccagat acccgcgacc
     5761 ttcgcgggtg ccgcggtcac cgtcgccggt gccgcctgcg tacggctcct cgtccggtcc
     5821 cggtcccaac tccgccgtgc gaacgacgac ttccgcgccg cccaggccga gcagtcccag
     5881 cagcggtacg ccgaggtgcg cggccgggaa cagagattcg ccgccgagcg ctccgccctg
     5941 gaggcacaac tcggtgagca ggccgccctc ttcgaggccc ggctcgccga acacacccag
     6001 gcgtacgagg ccggcatcgc tgaacgggcc cgcgcgacgg aggagcggat cgcgctccag
     6061 caggccgtcg tcgtcaggct cggcgacagc tacctccccg aagctgtcgc gcgactgcgg
     6121 gacggtgagg ccatcgacga catcctggcc gaggccggcc aggagggcga cgcgagcccg
     6181 gagctgcgcg ccgcgctgcg caaggtcctg cggaccgcgc tgctctccgt ggaggaggag
     6241 ctcaaccgct ccacgtcggc cgagcaggcc gtcgtcggca tcggcagccg gatccacgtg
     6301 ctgacgggcc ggctgcgcgg ccggctgcac gagatgcagg gcgagcacgg gcggctgccc
     6361 gcggtggccc agggcctcat ggagctggac caggagatcg gccccgccga ctgcctcgcg
     6421 gccagcatcg gcgtcctcgg tggttccgac cggccgggac gccagtggca ggagccgcag
     6481 cggctgctca gcgtggtccg cggcggcatc gggcggatca aggacttcaa ccgcatccag
     6541 gtccgtcacc tgcccgaact cggcgtcgac ggcggtctgg tggaccacct cacgctgatc
     6601 ttcgcccacc tcctcgacaa cgcggcacgc tactcgccgc ccaccgagcc cgtggtcgtc
     6661 tccggcaagg aggtgcccaa cggcgtcggc atcgagatcc aggacgcggg caagggcctg
     6721 accgacgagc gcaagcgcga ggcggagcag tccatcgcgg gtacctcgaa gggccccggc
     6781 ctcggcggta tctcggagga cgccaacctg ggcctgcgtg tggtcggagc cctggcgcgc
     6841 cgctacggca tccgggtcac tttcgcggac tctccgtggc tcggcacctc cgtggtcgtg
     6901 gtggtgcccc acaagtactt cagccatctg cccgcccccg tcacggagcc ggccaggccc
     6961 gccgtggaga gggccgagcc ggtccccgag ccggccgtgg ccgccgcgcc cgtggctgcc
     7021 gcgcccgtgg aaagcaccga agcgatcgac accatggaca ccacgccggg cggtctgccg
     7081 cggcgcagga gcaggcgggc cgacgcgccc accgcccggc cggccggcgc cgaccggacc
     7141 gcggagtcca tggccgccgt gccgccggac gcgtccttcg ccggtctcgc cgccttcgcc
     7201 acggcggggc gtgagagcgg tccaccaggg ggtactgacg cggacgccgc cccgggcgcc
     7261 cgcgagacga ctgccggccg cgagtccaac cgcactgaag agagcgacta gtccacatga
     7321 cgcaacaggg aaccgacgtg agctgggcgc tccgggatct gacggagagc atccgggaga
     7381 tccgcttcgc cctcgtggcc tccagcgacg ggaaggccat cacctcctac ggcgccgacg
     7441 acccggacga cgtggaccgc ttcgccgccg tggtcgcggg gctgcaggcg ctcgcgcagc
     7501 cggtggccga gcaattcccg acgtatgcgg ggcagttgcg cctggcgatg atcgaggtcg
     7561 acggcggtca tctcttcgtg gtgcgggccg gtgtggagac gtacctcggg gtgctggcca
     7621 gggaagggct cgaccagggc ctgctcggtc accagatgag ggacctggcg cggaggatgg
     7681 gtgagcttct cggcaccagt ccgcgcctgg aggagcagcc tggatgagtg gtccccgccg
     7741 gcccacggac ccgcccggtc tcgagcgcta ctacgtcctc accggggggc gcagcggacc
     7801 gggtggttcg gcgtcgaccc tggacgtggc gaccctcatc atctcccgtg ccgcagccga
     7861 gcccggcctg cagcacgagc acgaggagat actgcggcgc tgccgcgatc cgttgtcggt
     7921 ggccgaactc ggcgcccacc tcggactgcc cttcaacatt ctcgcggtac tcctggccga
     7981 tctgctggac gcaggccgcg tggaggcccg cgatcccatc ccggcgtcag gcgccggccg
     8041 cgggcccgac ctcgcgctcc ttgaggaggt actcagtgga cttcaaaggc tttgaccatc
     8101 ccgaccggca gaccgccgga ggcggcaccc gctcggtgaa ggtgatgatc gccggtggtt
     8161 tcggtaccgg gaaaaccact ctcgtgcggt cggtcagcga catcaagccc ctcaccaccg
     8221 aggagacgct gacccaggcc agcgtcgacg tcgacgacct gatcggggtg gcggacaagc
     8281 agcagaccac cgtcagcctc gacttcggga agatcggcat caacgaggag ctggtgctgt
     8341 acctgttcgg gacgccgggc caggagcggt tctggttcct ctggaacggc ctgttcaagg
     8401 gcgccctcgg ggcggtcgtc ctggtggaca cccggcggct ggcctccagc ttccgggcca
     8461 tcgaggagat ggagcggcag gacgtgccct tcgtcatcgc cctgaacgtg ttcccggact
     8521 ccaaggacca cccggtcgag gagatccgcg acgccctgga catccccgaa cacaccccgg
     8581 tcgtgacctg cgacgcccgt gaccgcaact ccagccgtga tgtgctgatc gcgctgatac
     8641 gtcacctcaa ggcacgctcc gccgtcgctc tggagccccg atgaccgatc acccggccga
     8701 cgaagagggc gctccccggg gctgccccgt catgcacggc ggcgccgacg acctgacccg
     8761 gctgtacggg ccggacgcgg cggtcgaccc gcagggcatc tacgggcggc tgcgcaagga
     8821 gtacggagcc gtggcaccgg tgctcctgga gggggacgtc cgtgcctggc tggtcctcgg
     8881 ctaccgcgag agcaggcgcg tgctcgacaa ccccctccag ttcagccggg actcgcgcat
     8941 ctggcgggac tggcaggagg ggggcgtcga ggagacctcg ccgctgatcc agatgctcgg
     9001 ctggcgtccc gactgcgtgt cccaggacgg tgagccgcac cgcaggctgc gccgggccgt
     9061 caccgacaac ctggacaccc tggcggggcg cggcatccgg cgccacgtca cgcacttcgc
     9121 gaacaagcag atcgacgcgt tcgccgggag gggcagcgcc gacctggtgg gcgagtacgc
     9181 cgagtacctc ccgatgctgg tgctgaccag gctgttcggg ctcccggcgg ccgaggggcg
     9241 cagcctcgcg gccgcctgtg cccaggtcct caagggcggt cccgacgccc tcgcgcacaa
     9301 cgaccgcatc atggagatcc tcggggagct cgccgagcgc aagcggctcg aacccggccc
     9361 ggacttcacc accgggctgc tcgggcacac cgccggactc gacgagggcg agatcgtcag
     9421 ccatctccgt ctggtgctga tcaccgcgca caccacgacc agcaacctgc tggcccgggt
     9481 gctggagctg atcctcaccg acgcctcccg tctcgcggga ctcgtcagcg gccagcgggc
     9541 ggtctccgag gtcgtcgagg aggtcatgtg gaacaccccg ccgctggcgg tcctcccggg
     9601 gcgtttcgcg accgcggacc tcgagctcgg cggtacgcag atcaaggagg gcgacctgct
     9661 ggtgctcggg ctcgccgcgg gcaacctgga cccggacatc cgtccggact cgggagtctc
     9721 cgtacacggc aaccagtcgc acctggcgtt cagcggcggt ccgcacgagt gccccggcca
     9781 gaacatcggc caggccatca tcgagaccgc cgtcgacacc ctgctgcacc ggctgcccgg
     9841 gctgcgcctg gccgtgccgg ccgatgagct cacctcgacc gcctccacct gggaagcgcg
     9901 tctggacgcc cttccggtcg agttcgccgc gtagtccgcg cgggccctca ccgcaccacg
     9961 cgttcccgcc cggcctccac ggccgggcgg gttccgtgcg tcagacggcg agcaggtcgt
    10021 ccagcgatcc gcggccggcc agctcggcgg tggcggccgg gccctccttc gcggctgcgt
    10081 accggcccga ggtcagcgcc cactcgtagt tgccgccgat ccagtgctgg atggcctcca
    10141 cgcccagccg gacctgttcc cgctgctcgg cgccgaggcc cagctcctcg cacatccttg
    10201 ggacgagcgc ctcgagcgcc aggtactcgt cgaggcacac cgtcgtcatc cggtacgcct
    10261 cggcggcggc ctcctcccag gtgcagccgc gctcgcggtg caggacggcg atgaggttgt
    10321 ggccgtcgcc ccggcgcttc tcgcgctcga aggagtggat gtcgttcatg aacccgatgg
    10381 tgtccgcggc caggtcccgc atccggacca tcagcgggtg cgcctgcacc tgcgccggga
    10441 cctcgaagcc gcggctgcgc tcacccgcgt cgatgctgtg gtggatgccc acggtgcggc
    10501 ggcggaactc ggcgtactcc tcgacgccga gcgtcccggc gcggccctcg gccgccaggt
    10561 cgacctcctc ggtgtgcgcc acgaggaaac ggccccagga ggcggcgaac cgtgtctgcc
    10621 aggtcaggga catgccatcc gagaggtggg cccacacctg cgcccaggcc acggtgatcg
    10681 ggcagaccac gcgcggggcc gtcccggccg ggcgcagcgg cgtggctatc agctcccgcg
    10741 cgacctccgc tatgcggtcc gcgcggtcgg ggcttccgga gtcgaactgg tcgtcgaaga
    10801 ggaaggccag cgagaaccag ttcatcagga cgaccatgtc ctcggccgag gcgtacgggt
    10861 aggtccgcgc cgccgcctgg ggcaggtccc aggactggta ttcctcgaac ccggcctggc
    10921 tgcgtaccag gcccatctcc cacacccagc gcaggtggtg ctcccgtgcg tacgcgaggt
    10981 gtgcgctgac cggggtctcg aaggggaggt cgaatgtgac gtcctgcggc attggcgtcc
    11041 tttcttgcgg cgattcacag gcccccgccc cgtgacaggg cgatcgggat tgacgcccat
    11101 tgactcgaag tgcacgtttt gagtccaaaa ttgacggctc atcatgcgcg ccctgatgct
    11161 gcccagaccc taaacgatct atgcaacaag atccgctcga aggaaatctt ccggaacggc
    11221 gcgttcagca tcgccggccg gacccgaacc ggaacgggaa cctgatccga accggaacct
    11281 gatccgaacc ggaacctgat ccgaaccgga acctgatccc gaaccgggtc ccgggccgcc
    11341 gtcagccgct cagggccgcc gcggtggccc ggacgaacgc ctcggggttg tccagcatga
    11401 tgttgtgccc gcagtcgggg accgggacca cgaggacacc cgcgctccgg agctccccgg
    11461 cccccgcgag cggaccgtcg gcctcgggga agaggaacgc ccgggggatg gtcaggcgca
    11521 gcagcagctc acgcatcacg ggggaggtcc cacgggcgag gtggaccgcg ctgcggtaca
    11581 gggcctcccg gcccgccagg cgcatcgtcg cccaccagtg ggctcccgcc cggtcccgca
    11641 cctgctccca gccgccctgg aggaactcct gctccgtgta cgcggcgatc cccgcgctgc
    11701 ccggtgcgcc gaccgcgggt gtgaccgggt cgaggttggc gtcggccagg accaggcggg
    11761 agaccaggtg cggatggcgg gcggccagga cgagggcgac cgagcctccc atgctgtgcg
    11821 cgatcacctc ggcgccggtg accccggcct cgcggagcgc ggcggccagg gcatcggcgt
    11881 gcgattccag ggtgtagtcg aaacccgtcg gccggtcgct gatgccgtgg cccatcaggt
    11941 cgacgagcag cgagcggtgg ccggcgagag cggggtggga ggcggtcgcc gcgaagtacg
    12001 cgggcgaggt ggccccgagc ccgtgcacat agacgcgggt gggctcccgg ccgggcagtt
    12061 cggcccagcg gatccggtca ccctccgctg tgacgacggc gtcgcgcact ctctgctccc
    12121 tgggtcgtgt ccgggtggga ggtgagcgta gccgccgggg acccggccgt atgacgccgg
    12181 gtcagacctg gcccaggtcc gagctgagcc agcgctgggg gcgcatgtgg atgacgacct
    12241 gctcgccgtg ttccttccag gcgaagtcga cgtaacccgc gaccttctcg gcggggaggt
    12301 agcgcgacga gatctccacc agttgctcgc gggtggcggg gagcgtggcg acgacggggc
    12361 cctcgacgga gacgtagcgg atggtcggcg agacgcgctc gaccatgatg ctgaagcggc
    12421 cggcggcggc gatggcggtc cccttgcggg agtcgcgccc cgtcatgacc cacaggtcgc
    12481 cgccgggcgc gtactggtac cagatcggca cggtgagcgg ggcccggccc tcctccggtg
    12541 cgtccaccgc gagtgcggcg atgtgcggtt cggccaggaa cagctcgcgc tccgtacggg
    12601 tcaaagccat ggtcgggctc ctcaggtggg cggtcggtgt tgcctcaggg ccgcattatg
    12661 caacgccctc cccggcccgg cgggggagtc acacgctctc ccggtccgcg tgttcccggg
    12721 cgcggtaccg gcggacggcc ctggtatacc tgggcgttca ccggcgaagg gggagcgacg
    12781 gcatggctca ggacacatcc gtacggctgc gggaggcgac cgccggggac gcggaggagg
    12841 tcacccgggt ctacctcgcc tcgcgggccg ccgcgctgcc gtacctgccg cgggtgcaca
    12901 gcgacgcgga cacgctcgcc tggatcaccc atgtcctgct gcccggcggc aggacatggg
    12961 tggccgaggg ggaggcgggg gagctgctcg gcttcgcctc tctggacggg gacgagctcg
    13021 accagctcta tctgcgcccc gacgtccggc ggcggggcat cggcacgctg ctgctggagc
    13081 gggcgaagga ggcctcgcgc ggcgagctga gcctgtacac cttccggcgc aatgccgccg
    13141 cgcgcgcctt ctacgagcgg cacggcttcg tcgccgaggc gtacgacgac ggcggccgca
    13201 acgaggagaa ggagccggac gtgctgtacc ggtggacggc ggcggggctg ccggccgaca
    13261 gctccgacag ctccggcagt cgcgggaccg ccggagcggt gtgagcgctc ggatgaccgg
    13321 cggcccgggg acccccggtc atccccgaac gatcagatga ccggcggccg gcccaggcgc
    13381 gtcatccgcc acaccgtgcg ccagcgcatc ggcttccgtt cgccgcactc ggtgcgcacc
    13441 ccctcggcga agcccgcacc ccaggcgcgc agcccggagg ccgagcgggt gcgggcggcg
    13501 gtgagcagga tccaggtgcc gaggtaggcg gggacgaggg ggaggggcag gttgcggcgc
    13561 gccagccaga cgcggttgcg ggcggtcatg cggtagtaga cggcgtgccg ggccggggac
    13621 gtcctggggt gctggagcag caggcggggc tcgtagagga tcttccagcc cgcgtccagc
    13681 gcccgccagg acaggtccgt ctcctcgtgc gtgaagaaga actcggccgg ccagggcccc
    13741 gtctcggcga gcatccgcat cgacagcgcg tggccgccgc cgaggaaggc ggtgaccggg
    13801 ccggggcgca tcgggtcctt ggcgcgcagc cgcggtacgt gccggcgctg ggtctcgccg
    13861 tgctcgtcgg cgatgcggaa gccgacgatg ccgaggtccg ggtcggcggc gtacagctcc
    13921 tggaccgtac ggaagacgtc cttgtccacc aggagtccgt cgtcgtccag ctcgatcacg
    13981 acgtccacgt caccgaagcc ggcgagttcc tccagggcct cgttacggcc gccggggcag
    14041 ccgaggttct cgtcgagttc gagcaccgtg acgccgccgg acaggtcctc caggccgggg
    14101 aaggagccgt agtcggggag cggtgagccg ttgccgacga cgaccacccg ggcggggcgc
    14161 acgtcctgca tggccaccga cgccagcagg gcctcgacct gctgcgggcg gtctcccatg
    14221 gtcacgacgg atacgccgat gcgtggttcg gacaaggctc ggctctcccg ggggatctcg
    14281 gtggatcggg caccgcggca caccgcggtg cccgcgatcg taacgtccgg tgttcaggcg
    14341 ccggtggggg cccggtcacc ggaaggacgg tcgccgttca gctgcgcgta catcagcatg
    14401 tcccggcgcc ggccgccgat ctcctgccag ccgcgcatca ggccctcgcg ccggtaaccg
    14461 gcgctctcgg ccgtccgtac cgaggccgtg ttacacggct cgacgaggag ctgcacccgg
    14521 gggatgcgca gctcgtgcag ggcccaggtg gtgaccgtgc gcagggccgc ccccgcgacg
    14581 ccctggccgc gcaccggggc cgtcatccag tagccgagtg tcgcccggcc ctgcgccacg
    14641 tccgtcagcc agagcccgat ggagccgacc ggccgccggt cccgggtgcg cgcgatggcg
    14701 aacggatagc cctccccgcg ggccgcccgc tcccactggc gtctgacgta ggcctcggcc
    14761 gcctcgtcgg agtacggcga ggggatcgtg gtgaccagcg ggatgtagtc gtcctgggcc
    14821 gcctcgcgga cgaggggcag atcgctcatc tcccagggcc gaaggacgaa gtcggctccg
    14881 gcggtcatgc tggggacggt cagcggttgt gccatgcccg tcatcctgcc gcgcccacct
    14941 cccgcgaccc gggcccgact cacccaccgg cccgcccgga gaacgccccc gggacacgca
    15001 cgggccaagc acgggggaag ctacgggaag agctacggga agagctaacg gccccatggt
    15061 tccgttaaaa tggtgcggtc gtggcaggac aagggcggtc ggcaggcggt cggcggaacg
    15121 ggagacaccg atggagccag cggcagggga cgcggtggac gtcgagccgg gcacggtccg
    15181 gcccggcggg cgcacggccc gggtgcggga ggccgtgctg cgcgcggccg gtgacgccct
    15241 ggtcgagcag ggcttcgacc ggctcgatct cgccgacgtc gcccggcgcg ccgaggtcgg
    15301 caagacgacg gtctaccggc gctggtccac cgcggcggga ctggtcgccg atctgctgac
    15361 ggagatggcc gagcagtccg tgccgcgcgc ggacaccggg tccctggacg aggacctgcg
    15421 gtccaacgca cggctggtgg tgcggacgct gaccgacccg cgccagggcc ccctcttcac
    15481 cgcggtcgtc gcggcggcga cgtgcgacgc ccggacggcc ggggccctgc accgcttcta
    15541 cgcggtccgc atcgaggagt gggcgggctg cgtcgacgcg gcggtcgccc ggggcgacct
    15601 gccgccgggt accgacgccc gtgaggtgat ccgcgccgtg tcggcccccc tgtactaccg
    15661 gctgctcgcc agcggcgacc ccctcgacga gacggtcgcc gaccgcgcgg ccgaagcggc
    15721 ggcggtggcc gcgcgggcgg gcgtgtacgt gcgctgacgc cggaggggca gcgcttgact
    15781 tgtcgtgcac tccaactcgt agcttctgcg cccatgcaga cagacatgga tcgacggaag
    15841 aggacgcagg accgcggcgg gttcgaggcc ggtgcgctcg gcttcgggtg ctgggcgatc
    15901 ggcggggagt ggtcggcccc cgacggcagc ccgctcggct ggggcacggt cgacgacgac
    15961 gagtcggtgg ccgcggtccg ccgggcgctc gacctcggcg tcacgttctt cgacaccgcg
    16021 gacgtgtacg gggccgggca cagcgaacgc gtgctgggca gggcgctcgc gggccggcgg
    16081 gacgaggccg tcatcgccac caagtggggc aacctgttcg acgagcggac ccgcaccatg
    16141 gacggtgccg acacgtcccc cgcgtacgcc cgtcaggcgc tcgtcgcctc gctgcgcagg
    16201 ctgggtaccg accggatcga tctctaccag ctccacctcg gcgacacccc gctcgacgag
    16261 gcggccgaac tgcgcgacgc ctgcgaggag ttcgtggcgg aggggctgat cagggcctac
    16321 gggtggagca ccgacgaccc ggagcgtgcc gcgctcttcg ccgacggtga gcactgcgcg
    16381 gccgtccagc acgcctgcaa cgtgctggag gacgcccccg ggatgctgaa tctcagcgag
    16441 gagcggggcc tgttcagcgt catccggagc ccgctggcca tgggcctcct caccggcgcc
    16501 cgcgatccgg gccggcgggc cgccgcgggc gacatccggt ccaccccgcc cgcctggctg
    16561 agctggtacg agcagggcgg ggtcccggcg cggcactggg cggcacgggt cgaggccgtc
    16621 cgcgaggtgc tgaccgccga cggccgcacg ctcgcccagg gggccctcgg ctggctctgg
    16681 gcccgcagcg ggcgggcggt gccgatcccc ggcttccgta cggtcgccca ggccgaggag
    16741 aacgcggcgg ccctcaccca cggcccgctg cggcccgcgc agctggagga ggtggccgcc
    16801 ctgctcgcct gagctgccgc cgctgccgct gctgccgcgc gcgaggccgg gccgcccccg
    16861 ggtcaggcct tccgggcgac cgccacgtac tccccgctgt gcgcgctctc ctggccgggg
    16921 accggttcgc cgagttccgg gtgccactcc tcggcggcca cgacaccggg ggcgaccagg
    16981 tcgagcccgt cgaagaagcg ggtgaagcgg tcgcggtcgc gcatgtccag ggtgaggccg
    17041 ttggccttgt acatgtcgcg gaccttctgc gacgcctcct cggggtggaa gtccggggtg
    17101 aggtgcgaga tcaccaggta gctccccggg gccagcgcgg ccgtgagctg ttccaccacc
    17161 tcgtacgccc ccatctcgtc gctcaggaag tgcagcagcg cgttcaggga gagggcgacc
    17221 gggcggccga ggtcgaggac cccggccgcc tcggccagga tgcggtccgt ctcccgggcg
    17281 tcggcctgta cgtaaccgag cgcgccctcg tcggagccgt tgagcagggc ctgtgcgtgg
    17341 ctgaggacga cggggtcgtt gtcgcagtac acgacccggg cgtccggaac ggtcgtctgg
    17401 gccacctggt ggaggttggg ttcggtcggg atccccgtgc cgatgtccag gaactgacgg
    17461 atcccctgac cggcgagcca ccgggtggcc cggtgggtga acgcccggtt catgcgggcc
    17521 atcaccggta tgacgggggc gaaggcggtc agccgtctgc ccagctcctc gtccaccggg
    17581 tagttgtcct tgccgccgag gtaccagtcg tacagccgtg cggggtgcgg cttggtggtg
    17641 tcgatctcga tggaggtcat gtccgtcccg ttctccgatg cggcatcacc ggccgtacgg
    17701 ggacgggatg tcgagcaact gatcaacctg ccggaagcat aggcaggttg gccccggagt
    17761 gcggagggag cgctcagccg atccgggtac ccgttccggt caccctgacc cgcgggtcac
    17821 ccgtccgcag cccgacggtg agggtgccgg gccggcccat gtcggcgccc tggtgcagcg
    17881 tgaggaccgc gtcgtgcggg acgagcccga gctcgcgcgc gtacgccccg aaggccgccg
    17941 ccgcggcgcc cgtcgtcggg tcctcgacga cgccgccgac cgggaacggn tcgcggacgt
    18001 ggaagaccgt ggccgactcc cgccacacca gctgcacggt cgtcaggccg agccgctgca
    18061 tgagggcctc cagccgggcg aagtcgtacg acaggtccgc gagccgttcc cgggtcgcgg
    18121 cggccagcac caggtggcgg gcgcccgcgt aggcgatacg gggcggcagc gccgggtcca
    18181 gatcggcggc cggccagtcc agcgcggcca gcgcctcggc cacgtcctcg ggggcggcgt
    18241 cctcggtgtg cggttcgacg ctggtcaggg tggcgcgcag ctcgccgtcc tcgcgtacca
    18301 cggtgaccgg gacctggccc gcgagggtgg agaacaccag atcgcccggg ccgtcccgct
    18361 cggcgagcgc gagggcggtg gccaccgtgg catgaccgca gaaggggacc tcggccttcg
    18421 ggctgaagta gcggaccgtg tgcccgccgc ggccgtccga ggcagtgagg aacgccgact
    18481 cgctgtaccc cagctccgcg gcgacggcga gcatcgccgc gtcgtcgagg ccggaggcgt
    18541 ccagcacgac acccgccggg ttgcccccct cgggatcggc ggagaacgcg gtgtaccgga
    18601 ggacctcgga gtcggtgtgt gtgctcatgt cgcaggtcaa ccgggaggcg tcgccgctca
    18661 ttcccgcccg cgcccacgag cgtgcccgcg gggtggtggc ccgggtcctg acccccggac
    18721 caccacccct ggccgctccc acggaccccc cggccgcggc ggcccctttc actgcggtca
    18781 gtggcagacc ttcacgccgg tgcccttgcc ccaggagcag gagtccagga gcgcaccgct
    18841 cggcttgatc agccgggcct tgtcgccggt gttgttccag acgtacgagc cgcggttcca
    18901 gtacacgtgg gcggcggagt tcttgccctt gccggtgtgg acccggaccg tcttccccgc
    18961 cgcgatgctg aagctcggga aggtgtaggt gtagccggtg ttgtccttca gcttgtagcc
    19021 cttgagctgg agcttggact tgccgttgtt gtggatgtcc acgtactcgg cgaccaggga
    19081 cgtgttcgtc cgggtgtcct tgccggggct gtcgtactgg atcttgccca ggtgcagccc
    19141 gccctggtgg gaggccgcgg aggccgggac cgaggcgagg agcgagccgg ccagtgcggt
    19201 ggcggcggcc agggcgaggg gcgcggcggt gcgtatgcgc atgctgtgtg gtccttctgt
    19261 gtacatccgg tgaaggccag tagcatacgg gcagcatgcg cttgcccgga cgcatcgcgg
    19321 gaaactcgca aattctgtca ttcgagagcg agttacagcg tgttccgatg cgttccgggc
    19381 aagcgtgggg tgaagtggat cagccccggc cgacgtacgg catggcggtc gccatcaccg
    19441 tcgcgaactg cacattggcc tccagcggca gctccgccat gtgcaggacc gtccgggcca
    19501 cgtcgtccgc ggccatgacc ggctcggcgg ccagctcgcc gttggcctgg aggatccccg
    19561 tactcatgcg ctcggtcatc tcggtggccg cgttgccgat gtcgatctgc ccgcaggcga
    19621 tccggtacgg ccgcccgtcc agcgacagcg acttcgtcag gcccgtcacc gcgtgcttgg
    19681 tcgccgtgta ggcgacggag tgcgggcgcg gcgcatgggc cgagacggag ccgttgttga
    19741 tgatccggcc gccctgcggg tcctgctcct tcatcaggcg gtacgccgcc tgcgcgcaca
    19801 ggaacgtccc cgtcagattg acgtccacca ccgtccgcca gtcctcgtac gcgaggtcct
    19861 cgacgggcgt cgccccgggc ccgaacgtcc ccgcgttgtt gaacagcagg tccagccggc
    19921 cgaaacgctc ccgtacggag gcgaagagcg cggccaccga gtccgggtcg cccacatcgg
    19981 tgggcaggca caccgtggcg cccgggccgg ccgcggcggc cgtctcctcc agcgccccgg
    20041 cccgccgccc cgccagggcc accgtccagc ccgcacccgt gagggtgagt gcgacggccc
    20101 ggccgatccc cgatccggca cctgtgacga cagcgattct ctgctcagcg ttcatggccc
    20161 ggcagcgtac gggaggtttc gcggcggccg gcacccggtg ctcatcgcac cgccatacgg
    20221 atgtggtgta cgcgccgacg ggacgtcgtc gccccgcact ccaatgcctc tgacaacatc
    20281 cggcagggga ggggcatatg acacccgcac agatcagcag gacgcccggc cagcacggcc
    20341 attccgccga gctgcgcctc gccgcgcaga agatcggatc cggcgtgggc cggcgccgtt
    20401 tcctcacggt caccggcgcc gccgcggccc tggccttcgc ggtcggcctg cccggcgcgg
    20461 gcacggcggc ggccgccgag ctcgacaccc ggaagatcac cgaggacccc ttcacgctcg
    20521 gggtggcgtc cggggacccg ctgccgtcgt ccgtcctcct gtggacgaga ctcgcgcccc
    20581 gcccctacga ggccgacggc gggctgcccg cccggcgcgt cgaggtccgc tgggagatcg
    20641 ccagggacga gcgcttccgg cggatcgtcc ggcgcggttc cgcgaccgcc cacccggagt
    20701 tcggacacag cgtccacgtc gacgtggacg gcctcgacgc cgaccggagc ttctactacc
    20761 gcttccgcgc cggcagctgg accagcccca ccggccgcac ccgcaccgcc cccgcccgca
    20821 acgcccgcaa cagctccctg accctggccg ccgtctcctg ccaggcctac cacgacggct
    20881 acttcacggc ctaccaacac ctcgcgnacg aggacgtcga cgtggtcttc cacctcggcg
    20941 actacctcta cgagtacgcc gtcaccgcca ccgggggcgc ccgcggctac accgaccgcg
    21001 tcctgccgga ccacttcaac cgggagacgc tc
//
