LOCUS       NZ_RDBM01000035        10204 bp    DNA     linear   CON 01-JAN-2025
DEFINITION  Streptomyces sp. gb1(2016) Scaffold_35, whole genome shotgun
            sequence.
ACCESSION   NZ_RDBM01000035
VERSION     NZ_RDBM01000035.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. gb1(2016)
  ORGANISM  Streptomyces sp. gb1(2016)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 2333361)
  AUTHORS   Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K.,
            Campbell,A.N. and Buckley,D.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University,
            306 Tower Road, Ithaca, NY 14850, USA
REFERENCE   2  (bases 1 to 2333361)
  AUTHORS   Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K.,
            Campbell,A.N. and Buckley,D.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University,
            306 Tower Road, Ithaca, NY 14850, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: A5+MeDuSa v. JUNE-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008042065.1-RS_2025_01_01
            Annotation Date                   :: 01/01/2025 02:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,414
            CDSs (total)                      :: 7,333
            Genes (coding)                    :: 6,887
            CDSs (with protein)               :: 6,887
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 447
            CDSs (without protein)            :: 446
            Pseudo Genes (ambiguous residues) :: 0 of 447
            Pseudo Genes (frameshifted)       :: 94 of 447
            Pseudo Genes (incomplete)         :: 395 of 447
            Pseudo Genes (internal stop)      :: 7 of 447
            Pseudo Genes (multiple problems)  :: 48 of 447
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:17:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 787880
            Orig. end                         :: 798084
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RDBM01000035.1.
            Annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (released 2013). Information about the Pipeline can be
            found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..10204
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..10204
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..10204
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:5204](-)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..5204)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(6..20)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 18.37"
                     /tool="antismash"
     gene            complement(259..2796)
                     /locus_tag="EAO74_RS14090"
                     /old_locus_tag="EAO74_14100"
     CDS             complement(259..2796)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016828175.1"
                     /locus_tag="EAO74_RS14090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_14100"
                     /product="FtsX-like permease family protein"
                     /protein_id="WP_187281817.1"
                     /transl_table=11
                     /translation="MMRPNGLARAAVRFKPASFAGTFLALLMSALIVAACGILLETGLR
                     ASVPAERYAKVPVVAAADQYVRVVTGSGEDREEEAVPLPDRARMDAGLAAKAATAPGAA
                     TAVADFTFPVRTADATPGSRELPVPGGALTAHGWGSHAFTGTALTTGSAPHDGEVVLDA
                     GTARAAKAAVGDTVTLRTAAGRRDFRVAGVAEAGPGDTARNTGAGDALAWFADTQAPAL
                     AGHPGRADAIAVLAEPGTRAGALAGSVRTALAGSGAGVHLGDDRGAVEDPGLGYAKETL
                     FGIGGSFGGIATIVAIFTAAGTVALSVSQRAREFALLRAVGATPRQIRRAVASEALLVA
                     PLAGIAGCLPGIGLAHWWFGQLQDRGAIPEAVRVHVSWIPLLVAVATGLLTALAAGWAA
                     GRRPARTKPGQALTEASVERLRPGVVRTVLGVAALVGGAILTGVSANSAGDDAAGASLG
                     VVMCFMLAVALLGPLVARVCAGLFGLPLRGAGPAGELAAANSRTNARRLASAITPIVLA
                     MAFASTLVFMQTSESHIADKQLRAGLTADHVVTDPAGIPVDAAARAARAPGVEAVVGVL
                     STQVLIPVGSGEFAALQGAAVQGVTGSGEDLAKVQDLDVREGSLDRLGAGRIAIDTTLA
                     TSAGVGVGDPLPLHLPDGTKARPEVVAVYGHGLGLATVTMDRASLAGHVTSGFDSTLLV
                     RGGSEESLAGFGEVTDASGYATGRSLDAELGAWSNTTMAAVLGGFAAVAAVNTLVMTVL
                     DRRRELGTLRLVGSTRRQVLQMLHWEGLLVSAVGVTLGTAIAAATLIPMIRGLTGDGPY
                     VPPLVYGSFVAAAVALVLLAVTLPARAALRRWS"
     gene            complement(2793..3878)
                     /locus_tag="EAO74_RS38535"
                     /old_locus_tag="EAO74_14105"
     CDS             complement(2793..3878)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003975187.1"
                     /locus_tag="EAO74_RS38535"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_14105"
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="WP_147983744.1"
                     /transl_table=11
                     /translation="MDTSVTTRGTAPATPVTGAAASLRKLYFLRFAFAAVWAGLLFATA
                     DTLGPLSAALLVVYPLFDVACAVVDARSARAVGGPVRGLYVNIALSTLTAVGLAVAATS
                     GIPAVLRVWGIWAVTAGLVQLVVGAVRRRLGGQWAMIVSGAISTLAGASFFAQAGADGA
                     TLSNLAGYAFLGGVFFLVSALRLKRPGEGGDGTADDHRPLAAQPASYGAYDELDEARGD
                     GPDAPDPQDRGDAGRGGDGEAYGGEGAGELSGGQQQRVAVARALVTAPDVVFADEPTGA
                     LDTGTAAEVLGLLRQAVDQLGATVVMVTHDPVAAAWADRVLFLADGAFADGVERGSAEL
                     IAERMAALTARTARVGAGVAA"
     misc_feature    complement(3924..3937)
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.69"
                     /tool="antismash"
     misc_feature    3975..3988
                     /note="TFBS match to LexA_variant_2, Repressor of DNA
                     damage response, confidence: weak, score: 18.69"
                     /tool="antismash"
     gene            4017..4622
                     /locus_tag="EAO74_RS14100"
                     /old_locus_tag="EAO74_14110"
     CDS             4017..4622
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014048110.1"
                     /locus_tag="EAO74_RS14100"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_14110"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_147983745.1"
                     /transl_table=11
                     /translation="MSRGTGSGSTSEARARLLGTATRIFYAEGIHSVGVDRIIAEAQVT
                     RATLYRHFSGKEELVLAYLDQADRGIRAQVASAQAEDAPAAERIRAVSRSITEGIRSPG
                     FRGCAFLNAVAEYPDPAHPIHQAVLAHRQWFLDTVTELLAEAGHTPAGAAGRHLVMLRD
                     GAMAEGCLFDPELVSETFLQAVEELLRARPASTGRVTA"
     gene            complement(5001..5204)
                     /locus_tag="EAO74_RS14105"
                     /old_locus_tag="EAO74_14115"
     CDS             complement(5001..5204)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: strepbact"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014153869.1"
                     /locus_tag="EAO74_RS14105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_14115"
                     /product="hypothetical protein"
                     /protein_id="WP_147983746.1"
                     /sec_met_domain="strepbact (E-value: 2.6e-15, bitscore:
                     53.7, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSAPQIQAQEISDADLDNVSGGTFAGLAGEVALETPLSSISAGF
                     SGALGVDGLGVAGLGSTSTLSA"
     misc_feature    5274..5286
                     /note="TFBS match to MatP, Cell cycle regulator,
                     confidence: weak, score: 19.5"
                     /tool="antismash"
     gene            complement(5702..7594)
                     /locus_tag="EAO74_RS14110"
                     /old_locus_tag="EAO74_14120"
     CDS             complement(5702..7594)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018518577.1"
                     /locus_tag="EAO74_RS14110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_14120"
                     /product="SMI1/KNR4 family protein"
                     /protein_id="WP_147983747.1"
                     /transl_table=11
                     /translation="MSDETFDWRDFLGRWQEEWVPGEDDEQDDEPPLAGPARPGADEAA
                     IAAAERRLGQRLPPSYREFLAASDGWRVEQTAAIYELGGAADIDWFHDPHGMTPLYEEG
                     LGDDPREEEVLLAGMWQRALRLETESDMSSALLDPGDRDQDGEWALYVYKGWSGEYPDR
                     YPSFRAYMEAMYRGFHGDRAGMPGFVNATTRAQDAHVEEARLLALRGRHEEALPLLEDA
                     LSFGRPHSATLLNQLRHLTAPQTARDYGFLVADPSCLPEILPLQAMEPARGERGPDGDA
                     HWLGMMAARGVPRETAEAVLGAVRDGTHRYAPPGPWGRAVAEAREAARWGATDAAWRVL
                     RAALPLWEAPGPQLIAPVGLLADPFLGPLVTPERGREILATPRAGEQGPAPDPVPDLDP
                     PGLAWLTESDPYRQADDGYRCVWAEGIDPARLPGLIGEEGSTLSAAMDQRWGRWRRASV
                     AETQEHAEPWEDRAPVAVGRTAGGWAFAFDRDPHHLGERFVSPAAAASASGRAVVVWHE
                     PGRPSPGDRPPTFHLSVAEQGEELYAFTVRGTEIQRSGAIPDALDPAGLFLPDATERDN
                     ELRALAALHTKLGLSLPRFALTRGRLSTFTTRSWTRAPREGESYAYIRFVRHRS"
     tRNA            complement(7649..7722)
                     /anticodon=(pos:complement(795567..795569),aa:Trp,seq:cca)
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.12"
                     /locus_tag="EAO74_RS14115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /old_locus_tag="EAO74_14125"
                     /product="tRNA-Trp"
     gene            complement(7649..7722)
                     /locus_tag="EAO74_RS14115"
                     /old_locus_tag="EAO74_14125"
     misc_feature    7742..7755
                     /note="TFBS match to PsrA, Oleic acid responsive regulator,
                     confidence: weak, score: 17.39"
                     /tool="antismash"
     misc_feature    complement(7951..7964)
                     /note="TFBS match to BldD, Development and antibiotic
                     global regulator, confidence: weak, score: 19.14"
                     /tool="antismash"
ORIGIN
        1 gatgatggcc gatctcgacc gctacctctc ccgcgacgac gccgatcccc cgaacgacgg
       61 cgtcctctgc cggcagggag cggtatgggt gacccccggg gagttcaccg aactggtggc
      121 ggaactggag gccctggtcg cccggtacgc ggggcgcgcc cccggcgacg accgcatccg
      181 tcacatcgtc agtctcgccc tggtgcccga cagggcggcc ggggaggagg gccgggcatc
      241 cgaggcgtag ggcacgggct acgaccagcg gcgcagcgcg gcccgtgcgg gcagggtcac
      301 tgcgagcagg accagggcga cggcggccgc cacgaaggag ccgtacacca gcggcggcac
      361 gtatgggccg tcgccggtca ggccgcggat catcgggatc agcgtggccg cggcgatggc
      421 ggtgccgagg gtcacgccca ccgcggagac cagcaggccc tcccagtgga gcatctgcag
      481 cacctggcgc cgggtggagc cgaccaggcg cagcgtgccc agctcgcgcc ggcggtcgag
      541 gaccgtcatc accagggtgt tgacggcggc gacggcggcg aagccgccga ggaccgcggc
      601 catggtggtg ttggaccagg cacccagctc cgcgtcgagg ctccgcccgg tggcgtagcc
      661 ggaggcgtcg gtgacctcgc cgaagccggc gagcgactcc tccgaaccgc cccgtaccag
      721 cagcgtgctg tcgaagcccg aggtcacatg cccggccagg gacgcccggt ccatggtcac
      781 cgtggccagg ccgaggccgt ggccgtagac cgcgacgacc tcggggcggg ccttcgtgcc
      841 gtccgggagg tggagcggca gcggatcgcc gacgccgacg cccgccgagg tggccagcgt
      901 ggtgtcgatg gcgatgcggc cggcaccgag ccggtcgagg ctgccttcgc gtacgtccag
      961 gtcctgcacc ttcgcgaggt cctcgcccga tccggtgaca ccctggaccg ccgcgccctg
     1021 gagcgccgcg aactcgccgg agccgaccgg gatcagcacc tgcgtgctga gcacgccgac
     1081 aaccgcctcc acccccggcg cacgggccgc tcgggccgcg gcgtccaccg ggatccccgc
     1141 cgggtccgtg accacgtggt ccgcggtgag gcccgcgcgc agctgtttgt cggcgatgtg
     1201 gctctcgctc gtttgcatga agacgagcgt cgaggcgaag gccatggcga gcacgatcgg
     1261 ggtgatcgcg gaggctagac ggcgggcgtt cgtacgggag ttggcggccg ccagttcacc
     1321 ggccgggccc gctccgcgca gcgggaggcc gaagaggccc gcgcacaccc gggccaccag
     1381 cgggccgagc agggcgacgg cgagcatgaa gcacatgacg acgccgaggg aggccccggc
     1441 cgcgtcgtcc cccgcggagt tcgcggagac gccggtgagg atcgcgccgc cgacgagggc
     1501 ggcgacgccc agcaccgtac ggacgacgcc cggacgcagc cgctccacgg acgcctcggt
     1561 gagcgcctgc cccggcttgg tcctcgcggg cctgcgcccg gcggcccagc cggcggcgag
     1621 cgccgtgagc agcccggtgg cgacggcgac gaggagcggg atccaggaga cgtgcacccg
     1681 taccgcctcg gggatcgcgc cccggtcctg caactgcccg aaccaccagt gcgccagccc
     1741 gattccgggc agacagccgg cgatcccggc gagcggcgcg acgagcagcg cctcggaggc
     1801 gaccgcgcgg cggatctgcc ggggggtggc tccgacggcg cgcagcagcg cgaactcgcg
     1861 ggcccgctgg gacaccgaca gggccaccgt cccggccgcg gtgaagatcg cgacgatggt
     1921 ggcgatgccg ccgaaggagc cgccgatccc gaagagcgtc tccttcgcgt agccgagacc
     1981 ggggtcctcg acggcgcccc ggtcgtcgcc gaggtgtacg ccggcgccgg agccggccag
     2041 ggccgtccgc acggatccgg cgagggcgcc ggcgcgcgta ccgggctcgg ccagtacggc
     2101 gatggcgtcc gccctgccgg ggtggccggc gagcgccggg gcctgggtgt cggcgaacca
     2161 cgcgagggcg tccccggcgc cggtgttccg ggccgtgtcc ccgggtccgg cctcggcgac
     2221 gcccgcgacc cggaagtccc gtcgcccggc tgcggtccgg agggtgacgg tgtcgccgac
     2281 ggcggccttc gcggcgcgag ccgtacccgc gtcgagcacg acctcgccgt cgtggggcgc
     2341 ggaacccgtg gtcagcgccg taccggtgaa ggcgtgcgag ccccacccgt gggcggtgag
     2401 cgcaccgccg ggaacgggga gttcacgcga gcccggcgtg gcatccgccg tgcgcacggg
     2461 gaaggtgaag tccgctacgg cggtggccgc cccgggtgcc gtggccgcct tcgccgccag
     2521 tccggcgtcc atccgtgccc tgtccggcag cgggacggcc tcctcctcgc ggtcctcgcc
     2581 gctgcccgtt accacgcgta cgtactggtc ggccgccgcg acgaccggca ccttcgcgta
     2641 ccgctccgcc ggcaccgacg cccgcaggcc cgtctccagc aggatgccgc aggccgcgac
     2701 gatcagcgcg gacatcagca gcgcgaggaa cgtcccggcg aaggacgcgg gcttgaagcg
     2761 gacggcggcg cgcgccagtc cgttggggcg catcatgccg ccaccccggc ccccacacgg
     2821 gcggtacggg ccgtgagcgc cgccatccgc tccgcgatca gctccgcaga accgcgctcc
     2881 acgccgtccg cgaaggcgcc gtccgcgagg aagagcaccc ggtccgccca ggcggccgcc
     2941 accggatcgt gggtgaccat gacgaccgtc gcgcccagct ggtcgacggc ctgccggagc
     3001 aggccgagga cctcggcggc ggtgccggtg tcgagggcgc cggtgggctc gtcggcgaac
     3061 accacgtccg gggcggtgac cagcgcgcgg gcgacggcca cccgttgctg ctggccgccc
     3121 gacagctcgc cggcaccctc accgccgtag gcctcgccgt cgccgccacg tccggcatcc
     3181 ccgcggtcct gcgggtctgg ggcatctggg ccgtcaccgc gggcctcgtc cagctcgtcg
     3241 taggcgccgt acgacgccgg ctgggcggcc agtgggcgat gatcgtcagc ggtgccatct
     3301 ccaccctcgc cggggcgctt gaggcggagg gcggagacca ggaagaagac gccgccgagg
     3361 aaggcgtaac cggccagatt gctcagcgtg gcgccgtccg cgcccgcctg cgcgaagaag
     3421 gacgccccgg cgagggtgga gatggcaccg ctgacgatca tcgcccactg gccgcccagc
     3481 cggcgtcgta cggcgcctac gacgagctgg acgaggcccg cggtgacggc ccagatgccc
     3541 cagacccgca ggaccgcggg gatgccggac gtggcggcga cggcgaggcc tacggcggtg
     3601 agggtgctga gcgcgatgtt cacgtacagg ccgcggaccg gaccgccgac cgccctcgcg
     3661 gaccgggcgt cgacgaccgc gcaggccacg tcgaacaggg gatagaccac cagcagggcc
     3721 gcgctcagcg gaccgagggt gtcggcggtc gcgaagagca ggcccgccca tacggcggcg
     3781 aacgcgaacc gcaggaagta cagcttccgc agggacgcgg cggcgccggt gacgggggtg
     3841 gcgggggcgg tgcctcgggt ggtgacggag gtgtccacgg gggtgccttt cggtggcggc
     3901 gcatcgatgg ggatgcgcgg gggagaacgt tcggtctctt gtggacatca aagggtgctc
     3961 cgggatggct gtcaagaccg aacgttctcc ctcacctgtt tggtagcctc gggagcatga
     4021 gtaggggcac aggaagcggc agcacgtccg aggcgcgagc caggctgctc ggtacggcga
     4081 cgaggatctt ctacgcggag ggaatccact ccgtcggcgt cgaccgcatc atcgcggagg
     4141 cgcaggtgac ccgggcgacg ctgtaccggc acttctcggg caaggaggag ctcgtcctcg
     4201 cctacctcga ccaggccgac cgggggatcc gggcgcaggt cgcgtccgcg caggcggagg
     4261 acgcgcccgc ggcggagcgg atccgggccg tcagccgctc catcaccgaa ggcatcaggt
     4321 cacccgggtt ccgcggatgc gccttcctca acgcggtggc cgagtacccg gaccccgccc
     4381 atccgatcca ccaggccgtg ctggcccacc ggcagtggtt cctggacacc gtcacggagt
     4441 tgctggcgga ggcgggtcac acgcccgccg gtgcggccgg ccggcatctc gtgatgctgc
     4501 gggacggcgc catggcggag ggctgcctct tcgacccgga gctcgtctcc gagacgttcc
     4561 tgcaggccgt cgaggaactg ctgcgggcgc gccccgcctc gacggggcga gtgacagctt
     4621 gacggggccg gtcgtggggg ccgggggcgg cgcctctcga ccggccggtg tgctcacggt
     4681 cgagtcgtct cgactcgtcg gtgtgctcac ggccgagtcg tacggctcat gtcggagacc
     4741 cgtcgtccgc ctccgggacc cgggctgccc gcgtggctac ctggaggggt gtggggcgcg
     4801 agcgtggcgc cgccccacgg ttgtccgggc cgccgggccg aggtgacact gtgtgtgggg
     4861 tgcgagcgtg gcgccgcccc acggttgtcc gggccgccgg gccgaggtga cactgtgtgt
     4921 ggggtgcgag cgtggcgccg ccccacggcc gctatgcccc gcggcctgac cggcatcggg
     4981 gcatacgggc tcgggtcggc tcaggccgag agcgtggagg tggagccgag cccggcgaca
     5041 cccaggccgt cgacgccgag ggcgccggag aatcccgcgg agatcgagga gagcggcgtc
     5101 tcgagggcga cctcgccggc caggccggcg aaggtgccac cggacacgtt gtccaggtcc
     5161 gcgtcggaga tttcctgggc ctgtatctgg ggggcggagc tcatgaggtg aattcctttc
     5221 acgttctgct tccgaatggc gggaggccga ccccgtcagg aaagaaggcc ccattgccgc
     5281 tgtcacgact gcggcttccg cggtgcgaag gatgaaagca cgtggacgcg tcacgaggcc
     5341 acccacccgg cagcgctccg gcctgctctt cctcaccgaa aaggcagggc ggtcacatcg
     5401 gttcgtggac cggtgcgaat tcttcacccg acaggacggc tgaatttccg tcggccgtat
     5461 tcctgatccg ccgcgaacgg gacattcccc gtaccggagg cgaggcgttc tccccgcgcc
     5521 gggagaacgg ccgtcacctg cgtgcgccgt gtggagatcc accgcagacg ggccggcgac
     5581 ggccttctcg gacccaggtc agggcccgac cggcgtgccc ggagcgatgt cgtacgccct
     5641 ctgtgcgcgg atacgggcat ttcggtcacc ctcggcagcg gtgggagcgt ggggtccgag
     5701 gtcaggaccg gtggcgtacg aaccggatat aggcgtagct ctccccctca cgcggcgccc
     5761 gggtccagga ccgggtggtg aaggtgctca ggcgcccccg ggtcagcgcg aagcggggca
     5821 gggacaggcc gagtttggtg tgcagggccg ccagcgcgcg cagctcgtta tcccgttcgg
     5881 tggcgtccgg gaggaacagg cctgcggggt ccagggcgtc gggtatcgct ccggagcgct
     5941 ggatctccgt accccgcacc gtgaacgcgt agagctcctc accctgttcg gccaccgaca
     6001 ggtggaacgt gggcgggcgg tcgcccggcg acgggcggcc cggttcgtgc cacaccacca
     6061 ccgcacggcc ggacgcggag gcggccgcgg cgggggacac gaaccgctcg cccaggtggt
     6121 gagggtcgcg gtcgaaggcg aaggcccacc cgccggcggt gcggccgacg gcgaccgggg
     6181 cccggtcctc ccagggctcc gcgtgctcct gcgtctcggc cacggatgcc cgccgccagc
     6241 gcccccagcg ctgatccatg gcggcgctca gcgtggagcc ctcctcgccg atcagacccg
     6301 gcagccgggc gggatcgatc ccctcggccc agacacagcg gtatccgtcg tcggcctgcc
     6361 ggtacggatc ggattccgtc agccacgcga gacccggcgg gtcgagatcg ggcacgggat
     6421 ccggagcagg gccctgctcc ccggcccgag gggtcgcgag gatctcccgc ccgcgctccg
     6481 gagtgaccag cggccccagg aacggatcgg cgagcaggcc gaccggggcg atcagctggg
     6541 gtccgggggc ttcccacagc gggagcgccg cccgcagcac ccgccaggcc gcgtcggtcg
     6601 caccccagcg ggccgcttcc cgggcctcgg cgacggcccg gccccacggg ccgggaggcg
     6661 cataccggtg ggtgccgtcc cgcacggcgc ccagtacggc ctcggcggtc tcccggggga
     6721 ccccgcgggc ggccatcatg ccgagccagt gggcgtcccc gtccggcccc cgttcgccgc
     6781 gcgccggttc catggcctgc aggggaagta tctcgggcag acagctcggg tcggccacca
     6841 ggaagccgta gtcccgggcg gtctgcggag ccgtcaggtg ccggagctgg ttcagcaggg
     6901 tggcgctgtg cggccgaccg aaggagagcg cgtcctccag caggggcagg gcctcctcgt
     6961 gccgcccgcg cagggccagc agacgggcct cctcgacatg ggcgtcctgg gcgcgggtgg
     7021 tcgcgttcac gaagccgggc atccccgccc ggtccccgtg gaagccgcgg tacatggcct
     7081 ccatgtacgc gcggaacgac gggtagcggt ccgggtactc gccgctccag cccttgtaga
     7141 cgtagagcgc ccactcgccg tcctggtccc ggtcgcccgg gtcgaggagg gccgacgaca
     7201 tgtcggactc cgtctccagc cgcagcgccc gctgccacat accggcgagc aggacctcct
     7261 cctcgcgcgg gtcgtcgccc agaccctcct cgtacagcgg ggtcatgccg tgcggatcat
     7321 ggaaccagtc gatgtccgcg gcgcccccga gctcgtagat cgcggctgtc tgctccacgc
     7381 gccacccgtc gctcgcggcc aggaactccc ggtaggacgg cggcagccgc tgccccagcc
     7441 gtctctcggc cgcggcgatc gcggcctcgt ccgctccggg tctggccggg ccggcgaggg
     7501 gcggctcgtc gtcctgctcg tcgtcctcgc cgggaaccca ctcctcctgc caacggccca
     7561 ggaagtcgcg ccagtcgaaa gtctcatcgc tcatggccag gatgctgcca tctgccaccg
     7621 acaacggcgc cggcaccagg gatccggtcg gcgccgaccg gattcgaacc ggcgtcctcg
     7681 cggttgtgga gaccggcgcg acgacctctg cgctacggct ccgcccggcc cggcatgcta
     7741 gcaaccgtcc gttcgcctgt gccgacggtc agttcgctca cccccgcggg tttctccgcg
     7801 tccgccgagc gcaccgtgag cctgacccgg cgggccggat cgcccgggtg gtacgggcgc
     7861 cacgcgcggc cgtccaggga ggtctccagg gtgtgggagg ccggtgcggt gtccgtccac
     7921 cggggcgtca gcgaagcgat ccgggtcacc tgacgcaggg tcaccgtcag cgtgcccgtc
     7981 gcgccgtccg gtgaccagga ggtcgacggg ctgccgtcca ccgccgcctc ggcgtacagg
     8041 ccgggcgcct cggacgtggc cgtcgccggg cggcagcggg ccgcgtcggt cgtcggggcg
     8101 aggtcgggcc gccgggtggg gagcgtgagg gtgccggaga ggcgtcgcgg ccccgccggg
     8161 gtgtggacgg tgaagggcgc gcccgccgtc agccggaccg tggtcgtccg ggggccgacg
     8221 gcgacgtcgt acgtacggcc ccggtagtgc agccccgtca gctccacgcc ctcgcggagc
     8281 tgcggcggca ggagcgggtc caggcgtgcg ccgtcctcgc gcagcctgag cccggtcaga
     8341 ccgtgcgtga acacctggag gaagccgccc ttgccggtga ggaagtcctc ggccgggaag
     8401 cccgagagcg ggtcctcggc cccggacttc tcgccccgcg cctcggagaa gaggctgtac
     8461 gggccccgga cgaacgggcg tacggcgcgc tggagatacg tgtacgtggc gcagcccggc
     8521 tccccggtcg cggcggcgtc gatcgcgtgc accgagtcgg tcatcgcggg gccgtccggg
     8581 tcggtgcggg cagcgtagta atcgagcgtc gcggcggcgg cgccctcctc catcggccac
     8641 tccagcgggt agaccagcag caccgtgtcg gcctgcttga tcgtcgagcc gttgtagccg
     8701 gcgtactgga ggaacagctt ccgatcggcg tcgtacggga tgcgcagccc gtcggcgacc
     8761 cgggtccagc cggcgggcgc cgggtggccg aggagggctg cggcgcgggt ggcgtggcgc
     8821 agggcagtgg cggcgaccgc gttggtgaag acgccgtcgg tgacgccgtt gctgtactcg
     8881 tcggggccgg cgacgttctt caccgagtag ctgccgtcgt cgttggccgt ggcgcgcgac
     8941 tgccagaagt cggcgatgcc cttcagcagc ggccagcccc gctcggccag ccaggcgcgg
     9001 tcgccggtgg ccaggtagta ctgccagacg gcgagtgcga tgtcgccctg gaggtggttc
     9061 tgggtgaggc agtgcggcgg gtcccagctc tggcactcgg agtccagacg gcccttgctc
     9121 gcgctcgtcc aggggtagaa cagccccttg tagcccagct tcccggcgtt cgcgcgggcg
     9181 gcggcgcggg tgcggtagcg gtactcgacg accgagcggg ccaggtcggg gcgggtggcg
     9241 agcagccccg gatacatcca ggtctcggcg tcccagaaca ccatgcccgc gtagttgtcg
     9301 ctggtcagcc cggccggggc gatgctgtcc gaggagccgg gccgggtgtt ggcgagcagt
     9361 ccgtactgcg cggcccgcag ccaggcctgg aggtccgggc tgcccggggt ccggacgtcg
     9421 gacgcccacg cctcgcgcca ggccgccgcg ttggcggcga ggaccccgga ccagccgcgc
     9481 cgggccgcgc ggtccgccgc cgcaccggcc gagacgagcg gggtgcggga ggtgagggcg
     9541 gtgtcgacgc ccacgtactt ctcgaaggtg tacgagcgcc ccgccctgac ccgggtggta
     9601 cgcgcgccgt cggtgccccg ctggacgatc gccccctccg tgccggtgcc gagcgtccgg
     9661 aacgtgccgt ccccggcgac cgtgacccgg cgcgccccgc gcgcgtccag ccggcccgtg
     9721 accgtcgcgg tgccgctcca gtgcggggtc atccgcaggc gtacggcgcc ggtgtggacg
     9781 tcggagcggt cggccagcac ctcgtaggtc aggtcggtcg cacgcccgtc ggccgtggtc
     9841 caccgcaggg acgtgatcac gacgccgcag cgcaggtgca gggtctggcg gtagcgggac
     9901 acacggccgg cgggggtggc ggagccgtac gtctcggagc cgacgcgcac gtcgagcgtg
     9961 gtccaggacg gcagcgcggc gatcacctcg cggccctcgg cgagggcttc gtcccgggcg
    10021 tggagccccg aaacgaaggc accgtcgtac cgtggggtgt agaggggcca gcccgtcttc
    10081 tcgcccgtgg cggcgtatcc ggcgccggtg gcgggcaccc ggtggcccag gtagccgttg
    10141 ccgacatagg ggtcgtatcc ggcggcctcg ccgaaggtgg tggacgtcgg tgcccaggag
    10201 gcgt
//
