LOCUS NZ_RDBM01000035 72573 bp DNA linear CON 01-JAN-2025 DEFINITION Streptomyces sp. gb1(2016) Scaffold_35, whole genome shotgun sequence. ACCESSION NZ_RDBM01000035 VERSION NZ_RDBM01000035.1 KEYWORDS WGS; RefSeq. SOURCE Streptomyces sp. gb1(2016) ORGANISM Streptomyces sp. gb1(2016) Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces. REFERENCE 1 (bases 1 to 2333361) AUTHORS Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K., Campbell,A.N. and Buckley,D.H. TITLE Direct Submission JOURNAL Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University, 306 Tower Road, Ithaca, NY 14850, USA REFERENCE 2 (bases 1 to 2333361) AUTHORS Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K., Campbell,A.N. and Buckley,D.H. TITLE Direct Submission JOURNAL Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University, 306 Tower Road, Ithaca, NY 14850, USA COMMENT ##Genome-Assembly-Data-START## Assembly Date :: 2018 Assembly Method :: A5+MeDuSa v. JUNE-2018 Genome Representation :: Full Expected Final Version :: Yes Genome Coverage :: 66x Sequencing Technology :: Illumina MiSeq ##Genome-Assembly-Data-END## ##Genome-Annotation-Data-START## Annotation Provider :: NCBI RefSeq Annotation Name :: GCF_008042065.1-RS_2025_01_01 Annotation Date :: 01/01/2025 02:23:01 Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline (PGAP) Annotation Method :: Best-placed reference protein set; GeneMarkS-2+ Annotation Software revision :: 6.9 Features Annotated :: Gene; CDS; rRNA; tRNA; ncRNA Genes (total) :: 7,414 CDSs (total) :: 7,333 Genes (coding) :: 6,887 CDSs (with protein) :: 6,887 Genes (RNA) :: 81 rRNAs :: 6, 1, 2 (5S, 16S, 23S) complete rRNAs :: 6, 1, 1 (5S, 16S, 23S) partial rRNAs :: 1 (23S) tRNAs :: 69 ncRNAs :: 3 Pseudo Genes (total) :: 447 CDSs (without protein) :: 446 Pseudo Genes (ambiguous residues) :: 0 of 447 Pseudo Genes (frameshifted) :: 94 of 447 Pseudo Genes (incomplete) :: 395 of 447 Pseudo Genes (internal stop) :: 7 of 447 Pseudo Genes (multiple problems) :: 48 of 447 ##Genome-Annotation-Data-END## ##antiSMASH-Data-START## Version :: 8.dev-cf2fc5ee(changed) Run date :: 2025-09-13 13:17:57 NOTE :: This is a single region extracted from a larger record! Orig. start :: 619963 Orig. end :: 692536 ##antiSMASH-Data-END## REFSEQ INFORMATION: The reference sequence is identical to RDBM01000035.1. Annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (released 2013). Information about the Pipeline can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ The annotation was added by the NCBI Prokaryotic Genome Annotation Pipeline (PGAP). Information about PGAP can be found here: https://www.ncbi.nlm.nih.gov/genome/annotation_prok/ FEATURES Location/Qualifiers region 1..72573 /candidate_cluster_numbers="1" /contig_edge="False" /product="T2PKS" /region_number="1" /rules="(t2ks and t2clf)" /tool="antismash" cand_cluster 1..72573 /SMILES="" /candidate_cluster_number="1" /contig_edge="False" /detection_rules="(t2ks and t2clf)" /kind="single" /product="T2PKS" /protoclusters="1" /tool="antismash" protocluster 1..72573 /aStool="rule-based-clusters" /category="PKS" /contig_edge="False" /core_location="[35000:37573](-)" /cutoff="20000" /detection_rule="(t2ks and t2clf)" /neighbourhood="35000" /product="T2PKS" /protocluster_number="1" /t2pks_malonyl_elongations="8|9 (Score: 704.7; E-value: 6.6e-215)" /t2pks_molecular_weights="acetyl-CoA_8 (Da): 347.340" /t2pks_molecular_weights="acetyl-CoA_9 (Da): 389.376" /t2pks_product_classes="angucycline" /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)" /tool="antismash" proto_core complement(35001..37573) /aStool="rule-based-clusters" /tool="antismash" /cutoff="20000" /detection_rule="(t2ks and t2clf)" /neighbourhood="35000" /product="T2PKS" /protocluster_number="1" /t2pks_malonyl_elongations="8|9 (Score: 704.7; E-value: 6.6e-215)" /t2pks_molecular_weights="acetyl-CoA_8 (Da): 347.340" /t2pks_molecular_weights="acetyl-CoA_9 (Da): 389.376" /t2pks_product_classes="angucycline" /t2pks_starter_units="acetyl-CoA (Score: 0.0; E-value: 0)" misc_feature 829..842 /note="TFBS match to ANR, Anaerobic transcriptional regulator, confidence: weak, score: 18.11" /tool="antismash" misc_feature 834..849 /note="TFBS match to DasR, N-acetylglucosamine dependent repressor, confidence: weak, score: 19.39" /tool="antismash" gene 1110..2726 /locus_tag="EAO74_RS13230" /old_locus_tag="EAO74_13240" CDS 1110..2726 /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]" /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1000: ABC transporter ATP-binding protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003954942.1" /locus_tag="EAO74_RS13230" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13240" /product="ABC transporter ATP-binding protein" /protein_id="WP_147984392.1" /transl_table=11 /translation="MKASSSPHAVELRGITKRFPGVVANHDIDITVSRGTVHALVGENG AGKSTLMKILYGMQKPDEGTISVDGEQVSFSSPGDAIDRGIGMVHQHFMLADYLTVLEN VVLGSEKLHGIGDRARAKIKEISDAYGLGIRPDAVVEDLGVADRQRVEILKVLYRGART LILDEPTAVLVPQEVDALFDNLRELKAEGLTVIFISHKLGEVLSVADEITVIRRGTTVG TADPATTTSKQLAELMVGSELPSPETRESTVTDTPMLAVEDLRLTATDPDGVVRAVLDG ITFTIHKGEVLGIAGVEGNGQSELVDAIMGMRTLDKGSLTLDGADISRTATRKRREDGM AVIPEDRHRHGLLLDAPLWENRMLGHVTERPNSKGAFLDLKAARADTERIVREYDVRTP GIEVTAASLSGGNQQKLIVGREMSHNPKLLIAAHPTRGVDVGAQAQIWDQIREARHEGL AVLLISADLDELIGLSDTLRVMYRGQLVADADPATVTPEELGSAMTGAAAGHLEAPGPT AAGDTAADGSETDPRDGGEDR" gene 2723..3838 /locus_tag="EAO74_RS13235" /old_locus_tag="EAO74_13245" CDS 2723..3838 /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003954941.1" /locus_tag="EAO74_RS13235" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13245" /product="ABC transporter permease" /protein_id="WP_124274352.1" /transl_table=11 /translation="MKKFDKERLLLGIAAPLLAIVVAFLVTALVLAATGKEPFSAFGIM FDYGLKSDSQVYILNKGTTYYLAGLAVAVGFRMNLFNIGVDGQYRLAAFFAAALGGALT LPGALQIPLIILTAMIVGAMWAGIAGLLKVTRGVSEVVSTIMLNSIATAIIGYLLQQGR LGHLDKAGTKVSTTPIPESSHFFEFPTTPTPVWGFIVIAVVAGVAYWFTLSRTRFGFDL RTVGQSGSAAEASGVDVRKMVVTSMLISGGMAGLIGMPTLLNDSYEYSGDFPVGIGFTG IAIALLGRNHPVGIALGALLWGFLERGTGKLEFEGYDKEIVGVIQGVIVLCVVIAYEVV RRYGLKRQQSKVGAELAAKAARNSDQQEVSA" gene 3835..5124 /locus_tag="EAO74_RS13240" /old_locus_tag="EAO74_13250" CDS 3835..5124 /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003954940.1" /locus_tag="EAO74_RS13240" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13250" /product="ABC transporter permease" /protein_id="WP_124274353.1" /transl_table=11 /translation="MSATATSTPPPAAPKVSGGKGGRTRFSFPVVLLIIAGALLALSAV RAITGAQDVTSAGQISAALAMAVPIGLAGLGGLWSERAGVVNIGLEGMMILGTFFGAWA GWQTDPWLGVLAGVVGGMLGGLLHAFATVTFGVDHIISGIAINILALGFTTYLAKLWFN TGDAAEKGGSPKQSPPADSITQVTVPGLSDWLHSLEKHHWFFVSDLAGILGGLVTNVSL LTLVAVLLFAGTFFVLWKTSFGLRLRSCGENPVAAESLGVNVYLYKYIAVIVSGGLAGL GGAFLSLVTSHIYNEGQTGGRGYIGLAAMIFGNWRPGGLAMGAGLFGFADALQLRNGGE SVHALLLLLVVMLAVLAVWKLYRKRFVPGVISAVIAAAVLVWYLATDTVPTEFVSATPY VVTLLVLSLSAQRLRMPKADGMRYRKGQGK" gene 5121..5522 /locus_tag="EAO74_RS13245" /old_locus_tag="EAO74_13255" CDS 5121..5522 /EC_number="3.5.4.5" /GO_function="GO:0004126 - cytidine deaminase activity [Evidence IEA]" /GO_function="GO:0008270 - zinc ion binding [Evidence IEA]" /GO_process="GO:0009972 - cytidine deamination [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018550457.1" /locus_tag="EAO74_RS13245" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13255" /product="cytidine deaminase" /protein_id="WP_124274354.1" /transl_table=11 /translation="MTDGAVPVDWDALRAAARDAMSRAYAPYSGYPVGVAALVDDGRMI TGCNVENASYGIGLCAECGLVSQLAATGGGRLTHFTCVDGTGAVLVPCGRCRQLLYEFG GPGLVLETPDGFRTLDEMLPQAFGPQHLG" gene 5659..6936 /locus_tag="EAO74_RS13250" /old_locus_tag="EAO74_13260" CDS 5659..6936 /EC_number="2.4.2.4" /GO_process="GO:0006206 - pyrimidine nucleobase metabolic process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015578471.1" /locus_tag="EAO74_RS13250" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13260" /product="thymidine phosphorylase" /protein_id="WP_124274355.1" /transl_table=11 /translation="MDAISVIRTKRDRGELSPEQIDWVIDAYTRGEVADEQMSALAMAI LLNGMNRTEIARWTAAMIASGERMDFGALSRPTTDKHSTGGVGDKITLPLAPLVAACGA AVPQLSGRGLGHTGGTLDKLESIPGWRAHLSNAEMLDVLDTTGAVICAAGDGLAPADKK LYALRDVTGTVEAIPLIASSIMSKKIAEGTGALVLDVKVGSGAFMKTIEDARELASTMV ALGTDSGVRTVALLTDMATPLGLTAGNALEVRESVEVLAGGGPQDVIDLTLALAREMLD AAGLKDADPEKALADGSAMDVWRRMISAQGGDPDAALPVARERHVISAPSSGVLTRLDA YDIGVAAWRLGAGRARKEDPVQAGAGVELHAKPGDTVTEGQPLLTLHTDTPEKFEYALK ALPGSYDIAPAGTPFTATPVVRERIA" gene 7040..7384 /locus_tag="EAO74_RS13255" /old_locus_tag="EAO74_13265" CDS 7040..7384 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_012379350.1" /locus_tag="EAO74_RS13255" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13265" /product="STAS domain-containing protein" /protein_id="WP_124274356.1" /transl_table=11 /translation="MSSGRSGGLPGVDAVTPNALVLTGRITRADVPGLCARLEALLSGA PEAAVVDCDVGGVVRPDLALVEAVARLGLVARRAGGAELRLRNVPAELGTLLDLMGLAQ VLGVVQAAPE" gene complement(7392..7679) /locus_tag="EAO74_RS13260" /old_locus_tag="EAO74_13270" CDS complement(7392..7679) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015578474.1" /locus_tag="EAO74_RS13260" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13270" /product="hypothetical protein" /protein_id="WP_147983684.1" /transl_table=11 /translation="MSVRRPVVIGWALLVAGGWAVTLWLGEPSATAGPGPSPAAGVRDE NPAPGPQPEGSCPTPSAAPSLKDVPDDYADGYVVQVLCDYGEARDTAVAR" gene complement(7676..8662) /locus_tag="EAO74_RS13265" /old_locus_tag="EAO74_13275" CDS complement(7676..8662) /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1032: RNA polymerase, sigma-24 subunit, ECF subfamily" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154446.1" /locus_tag="EAO74_RS13265" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13275" /product="sigma-70 family RNA polymerase sigma factor" /protein_id="WP_124274358.1" /transl_table=11 /translation="MSDQTATADIDSRLEGHRVELTGYCYRMLGSAFEAEDAVQDTLVR AWRNFDKFEGRSSLRSWLYRIATNVCLDMLNAGNKRARPVDLTGPTPLAQAALNPLPEN TWLEPMPDGRILPSVADPAEAAVARESVRLAFVAALQHLPPKQRAVLILREVLAWKASE VAELLDTSVASVNSALQRARATLSDTDSTAPDPANPLDDEQRKLLDRYVAAFEGYDMAA LTALLHEDAVMTMPPFDLWLQGHDDITGFMLSIGASCAGSRLVATRANGTPAFAHYKPN PDGPGFVPWAVQVIDISDGAITGMHCFLDTPRWFPLFGLPDHLDAGA" misc_feature 8682..8697 /note="TFBS match to CRP, Cyclic AMP receptor protein, confidence: medium, score: 17.4" /tool="antismash" gene complement(8760..9476) /locus_tag="EAO74_RS13270" /old_locus_tag="EAO74_13280" CDS complement(8760..9476) /EC_number="2.-.-.-" /GO_function="GO:0016740 - transferase activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010071906.1" /locus_tag="EAO74_RS13270" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13280" /product="L,D-transpeptidase" /protein_id="WP_147983685.1" /transl_table=11 /translation="MGIMGKIRGAGVRRGAVLSVAGLVVAPALVLGTGTAAQAASCTAA KGPYQKQVEKWLKRTADGKQSAADCKAIRSFQVAKGITPAIGYAGPVTWRTMKTITAQQ AAGKTPNKAKKCPTNKGRIACVDLTRQLSWIQDGSKLRFGPVPVRTGRNGAETRTGATK IYWRNIDHWSTLYDVRMPYAQFFDGGQAFHSVTKTMYNNPGSAGCVNMRPADAKSYWNL LRNGDDVFVYGRKPGT" gene complement(9566..10861) /locus_tag="EAO74_RS13275" /old_locus_tag="EAO74_13285" CDS complement(9566..10861) /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0022857 - transmembrane transporter activity [Evidence IEA]" /GO_process="GO:0055085 - transmembrane transport [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1184: major facilitator transporter" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018550450.1" /locus_tag="EAO74_RS13275" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13285" /product="MFS transporter" /protein_id="WP_124274360.1" /transl_table=11 /translation="MPPASTGASTVVLDAAVPSSTAAASPTVPDRLAPGGPGYRRMSFA LFAAGIATFALLYSTQALLPAVSASFGATAGQASWTVSAATGALALCVLPLSALSERFG RRQMMTASLAVAVVIGLLVPFAPSIGWLIALRAVQGAALAGLPASAMAYLAEEVRPKAL VAAIGLFVAGNSIGGMSGRILAGWVAQLWGWRMALGAIGLLAVACAVVFHLMIPRARHF SPASLNPKALARTVTGHLSDPLLRRLYAIGALFMTVFGAVYTVIGYRLVDEPFGLPQGI VGSVFLVYLVGTVSSAAAGRLVARLGRRGALYLAVSTTAAGLLLSLADQLVAVLAGLVL ITAGFFAGHAVASSSVSRTATSGRAQASALYQSAYYLGSSAGGTLGAVAFHAGGWAGTV ALGVLAVIGVLSITLFGTRAARTERLRAAVPN" misc_feature complement(10911..10926) /note="TFBS match to FuR_variant_1, Ferric Uptake Regulator, confidence: weak, score: 16.28" /tool="antismash" gene 10924..11877 /locus_tag="EAO74_RS13280" /old_locus_tag="EAO74_13290" CDS 10924..11877 /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1014: LysR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006127074.1" /locus_tag="EAO74_RS13280" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13290" /product="LysR family transcriptional regulator" /protein_id="WP_124274361.1" /transl_table=11 /translation="MAHQYSSQPRLSPSSYEEDIRAVLAPRLAYFEAVARHEHVTRAAH ELGVPQSTLSRAMVRLEQDLGVALFARRGRTVSLTPAGRTFLGSAERALAEVEKAADSV RADADPTAGKVAFGFLHTMGSETVPGLIRAFRVDHPRVRFQLVQNYGEAMIERLRAGGL DLCLTSPVPDAPDLVARRLDEQRLRLVVPDDHRLAGRRRIRLVEAADETFVTLEPGYGL RRITDDLCAEAGFTPRIAFEGEEAETLRGLVAAGLGVALLPPPAVARPGVVELTVTAPR AAREIGVAWLDGHPDTPPVAAFKRFLLSRRGSLLPD" misc_feature 10956..10971 /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2, activator of antibiotic production, confidence: strong, score: 18.42" /tool="antismash" gene complement(11894..12652) /locus_tag="EAO74_RS13285" /old_locus_tag="EAO74_13295" CDS complement(11894..12652) /EC_number="3.-.-.-" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_004984118.1" /locus_tag="EAO74_RS13285" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13295" /product="alpha/beta hydrolase family protein" /protein_id="WP_147983686.1" /transl_table=11 /translation="MAQRALPLPAARLGRAVLTAGAAPEVSGVVLLLPDGETDSRRRPS TLSYAAQLPFARALARAGQDDGLAVHVVRYRSRGWNSGADPAADAHWAADEVVRRYGDI PVCLVGHGMGGRAALRGAGHAAVTSVLAMAPWLPEGTEPEPEPVKHLAGRRVLIVHGTN DARTDPELSYRLAERAKKSNRDTCRFEVHSDGHALRQHRSEVVALASDFVRGSLFARSY ARPVADAFAAPPPLGLRMPLAAGFGRSLRR" gene 12779..13231 /gene="tnpA" /locus_tag="EAO74_RS13290" /old_locus_tag="EAO74_13300" CDS 12779..13231 /GO_function="GO:0004803 - transposase activity [Evidence IEA]" /codon_start=1 /gene="tnpA" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016434830.1" /locus_tag="EAO74_RS13290" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13300" /product="IS200/IS605 family transposase" /protein_id="WP_261988252.1" /transl_table=11 /translation="MRHLYSDRVTTARKVRRFSGGVCDLGLHVVWCPKYRRPVLSGRVA ERLDELIRTKADERGWEVNALEVMPDHVHLFVKHDPKSSASYVANQFKGFTSRVLREEF PHLKSRMPTLWSSSYFAASVGAVSAATVEKYIDTQWERPWKKGDGS" gene 13228..14436 /locus_tag="EAO74_RS13295" /old_locus_tag="EAO74_13305" CDS 13228..14436 /EC_number="3.1.21.-" /codon_start=1 /gene_functions="other (smcogs) SMCOG1192: transposase" /gene_kind="other" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_009320481.1" /locus_tag="EAO74_RS13295" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13305" /product="RNA-guided endonuclease InsQ/TnpB family protein" /protein_id="WP_147983688.1" /transl_table=11 /translation="MIRAYKFLLRPTARQVTALGEMLRDHCSLYNGALQERRDAYRHSS KSSIKYGNQSAQLKDIRAFDPDRQGRWSFSSQQATLRRLDKAFQAFFRRAKSGQTPGYP RFKGAGHFDTVTFPRDGDGCRWDSTPHDAQTRVRLQGVGHVRVHMHRPVQGRVKTISVK REGSRWYVVLACDDVPAEEMPPTGGNVGIDLGIAHFLTTSEGEHVANPRFLQAMADELA EAQRNLARFPKRARQRTKRHRAAARKVAKLHCKIRRQRADFHHKTARTLITDYDVIAHE RLNTVGMTKSPAPKTAPRQPGSFLPNGSAAKAGLNRSIFDAGWAQFLGILANKAESAGR LTVPVDARNTSRTCPECGHVAKENRVTQERFQCTACGFAANADHVGATNVLNRAGLVLC AEA" gene 14585..15739 /locus_tag="EAO74_RS13300" /old_locus_tag="EAO74_13310" CDS 14585..15739 /EC_number="3.5.4.4" /GO_function="GO:0004000 - adenosine deaminase activity [Evidence IEA]" /GO_process="GO:0009168 - purine ribonucleoside monophosphate biosynthetic process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_012379345.1" /locus_tag="EAO74_RS13300" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13310" /product="adenosine deaminase" /protein_id="WP_124274363.1" /transl_table=11 /translation="MTSQTLNVPGPDQIRRAPKVLLHDHLDGGLRPGTIVDLALEQGYE ALPETEPDKLGVWFREAADSGSLERYLETFAHTCAVMQTRDALFRVAMECAEDLAEDGV VYAEVRYAPEQHLTAGLTLEEVVEAVNEGFREGERRARAAGHRIRVGALLTAMRHAARA LEIAELANRYRDLGVVGFDIAGAEAGYPPTRHLDAFEYLKRENNHFTIHAGEAFGLPSI WQALQWCGADRLGHGVRIIDDIEIADDGSVTLGRLASYVRDKRIPLELCPTSNLQTGAA ASYAEHPIGLLRKLHFRATVNTDNRLMSGTSMSREFERLVDTFGYTLDDMQWFTVNAMK SAFIPFDERLAMINDVVKPGYAELKSEWLFRQTAVTSASSSVAG" gene 15875..16171 /locus_tag="EAO74_RS13305" /old_locus_tag="EAO74_13315" CDS 15875..16171 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018519132.1" /locus_tag="EAO74_RS13305" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13315" /product="hypothetical protein" /protein_id="WP_099173698.1" /transl_table=11 /translation="MKQSAVRTLGVAALGAAFAAAGAGSASAVAVPVDAAAAALPAGVA LDSVTDALPAVQKAAGGLLDQQQRGSSDLSAPGTNLLGGLPAGGLTGVLPLGN" gene complement(16249..16452) /locus_tag="EAO74_RS13310" /old_locus_tag="EAO74_13320" CDS complement(16249..16452) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006127080.1" /locus_tag="EAO74_RS13310" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13320" /product="PspC domain-containing protein" /protein_id="WP_099173697.1" /transl_table=11 /translation="MAALARPRDGRMIGGVCAALARRFGTSAGTMRVIFLVSCLLPGPQ FLLYLALWILLPSEKSPAATAW" gene complement(16545..17114) /locus_tag="EAO74_RS13315" /old_locus_tag="EAO74_13325" CDS complement(16545..17114) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018956032.1" /locus_tag="EAO74_RS13315" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13325" /product="VanZ family protein" /protein_id="WP_124274364.1" /transl_table=11 /translation="MHVRHSSDGPAVIRFRAAGVFLLLAHLLFVCWLTLRPLDVPWVTA ANFQPFAGIRADLALGPAEAVRRIGEGLLLLAPLGILLPMAGGRLLVSPWASLARTVAA GALISMAIELAQTGVPGQVVDVDSLLLNTSGVALAHLLIVPLSRSRLRRGNRAGAGDLS RIGARSVRAEGPQGSTPTITRVGIAP" gene complement(17227..17874) /locus_tag="EAO74_RS13320" /old_locus_tag="EAO74_13330" CDS complement(17227..17874) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154437.1" /locus_tag="EAO74_RS13320" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13330" /product="hypothetical protein" /protein_id="WP_147983689.1" /transl_table=11 /translation="MRRSERSYGAPREVLRRPGRAVAALAAVVACAALAGGCGIRSTSV PVDAGAAPSRMPCRTASAEASAPPAGSVSVPVYLVCASQLVTVERTVEFDESRSGPLMI AQELLGELQRDPEAAERRAGFSTDVPAGLRVTGAHKGDPEGTLRLSEQPDDLPAEALAQ VVCTYADSESLGSGGSVLLGGPGNYAPRGYLCTSETKSLPGEVPTLGAVGLS" gene complement(17871..19406) /locus_tag="EAO74_RS13325" /old_locus_tag="EAO74_13335" CDS complement(17871..19406) /EC_number="2.7.13.3" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1003: sensor histidine kinase" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018519128.1" /locus_tag="EAO74_RS13325" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13335" /product="sensor histidine kinase" /protein_id="WP_147983690.1" /transl_table=11 /translation="MSDTAKRSILAGLRWTSLRLRLLIVFALVALTAAVSASGIAYWLN REAVLTRTQDTALGDFRRQMQTQAASLPLQPTAVDLRDAAEQMASSGPGYHVLLIGTRE GKPVTGSSDLDSFTKADVPASLQRQVNKKQPLTSANTFEYHLFWQRTTVGGTPYLVAGT KIIGGGPAGYMLKSLDQEREDLNSLAWSLGIATALALVGSALLAQAAATTVLRPVQRLG DAARKLGEGKLDTRLVVSGTDELADLSHTFNKAASSLEKKVADMSAREESSRRFVADMS HELRTPLTAITAVAEVLEDEADSLDPMIAPAVHLVVSETRRLNDLVENLMEVTRFDAGT ARLVLDTVDVADQVTACIDARAWLDAVDLDAERGIMVRLDPRRLDVILANLIGNALKHG GSPVRVSVRTDEDDLVIEVRDHGPGIPQEVLPHVFDRFYKASASRPRSDGSGLGLSIAV ENAHIHGGDITASNLPDGEGAVFVLRLPRDAERLTGTQGPDDDPDGNEKGDAT" gene complement(19403..20080) /gene="afsQ1" /locus_tag="EAO74_RS13330" /old_locus_tag="EAO74_13340" CDS complement(19403..20080) /codon_start=1 /gene="afsQ1" /gene_functions="regulatory (smcogs) SMCOG1008: response regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003974066.1" /locus_tag="EAO74_RS13330" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13340" /product="two-component system response regulator AfsQ1" /protein_id="WP_015578482.1" /transl_table=11 /translation="MPFLLLIEDDDAIRTALELSLSRQGHRVATAATGEDGLELLREQR PDLVVLDVMLPGIDGFEVCRRIRRTDQLPIILLTARSDDIDVVVGLESGADDYVVKPVQ GRVLDARIRAVLRRGERESTDSATFGSVVIDRSAMTVTKNGEDLQLTPTELRLLLELSR RPGQALSRQQLLRLVWEHDYLGDSRLVDACVQRLRAKVEDVPSSPTLIRTVRGVGYRLD SPQ" misc_feature complement(20163..20178) /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2, activator of antibiotic production, confidence: strong, score: 19.52" /tool="antismash" gene 20262..21008 /locus_tag="EAO74_RS13335" /old_locus_tag="EAO74_13345" CDS 20262..21008 /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_function="GO:0016987 - sigma factor activity [Evidence IEA]" /GO_process="GO:0006352 - DNA-templated transcription initiation [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1032: RNA polymerase, sigma-24 subunit, ECF subfamily" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047967.1" /locus_tag="EAO74_RS13335" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13345" /product="SigE family RNA polymerase sigma factor" /protein_id="WP_124274366.1" /transl_table=11 /translation="MNALHSTTSSAVVTRLHDVGRSPEKSGVGGRGRARGAGRQHSSYL TMVDAATGENGGTAYGEGSGERKPLDRPEDAEAAFTAYVQERRASLYATAYHLTGDRFE AEDLLQSALFSTYRAWDRISDKAAVGGYLRRTMTNLHISAWRRRKLNEYPTEELPETVG DTDAMRGTELRAVLWQALARLPELQRTMLVLRYYEGRTDPEIASILDISVGTVKSSIWR SLRRLREDEVLSFGRDEEESFGELVA" assembly_gap 21054..21153 /estimated_length=100 /gap_type="within scaffold" /linkage_evidence="paired-ends" gene complement(21307..22011) /locus_tag="EAO74_RS13340" /old_locus_tag="EAO74_13350" CDS complement(21307..22011) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154433.1" /locus_tag="EAO74_RS13340" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13350" /product="uridine kinase" /protein_id="WP_129265181.1" /transl_table=11 /translation="MLDTNRTSRGSPTRVNASHFCSVSSQPIPTRVVLLAGPSGSGKSS LAARSGLPVLRLDDFYKEFNDPTLPRVTGSADIDWDSALSWDADGAVAAIAELCRTGRT SVPLYDIATSSRTGRETLDIERTPLFVAEGIFAADIVERCRELGLLADALCLRGRPSTT FRRRLVRDLREGRKSVPFLLRRGWRLMRAERRIVARQAALGAYPCAKQEALGRLADAAA GRCRTPRSRVPN" gene 22075..22500 /locus_tag="EAO74_RS13345" /old_locus_tag="EAO74_13355" CDS 22075..22500 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006127092.1" /locus_tag="EAO74_RS13345" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13355" /product="hypothetical protein" /protein_id="WP_099173692.1" /transl_table=11 /translation="MARHALSKPRKRTLLRAGLTLTALGAALGAGGAAAQAAPLPAPPA TGSDTADSTLGAVNEAAEPALNSVLGYGIVGAVKPITDLQLDPLAGTGVDPLDNAVGTQ IADFKPVTTALVTDPLTSGAALGDLPVVGEVTGLITG" gene complement(22558..23505) /locus_tag="EAO74_RS13350" /old_locus_tag="EAO74_13360" CDS complement(22558..23505) /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Aldedh" /gene_functions="biosynthetic-additional (smcogs) SMCOG1017: aldehyde dehydrogenase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_012379338.1" /locus_tag="EAO74_RS13350" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13360" /product="aldehyde dehydrogenase family protein" /protein_id="WP_147983691.1" /sec_met_domain="Aldedh (E-value: 2.2e-40, bitscore: 135.6, seeds: 89, tool: rule-based-clusters)" /transl_table=11 /translation="MSDGRLSVFKTYKLYVGGKFPRSESGRVYEVSDSKGRWLANAPQS SRKDARDAVVAARKAFGGWSGATAYNRGQILYRVAEMLEGRREQFVREVADAEGLSKSK AAAVVDAAVDRWVWYAGWTDKIGQVVGGANPVAGPFFNLSTPEPTGVVAVLAPQESSFL GLVSVVAPVIATGNTAVVIASADAPLPALSLGEVLATSDLPGGVVNILSGKTAEIAAPL ASHQDVNGIDLTGADAELAKELEIAAADNLKRVRRPPVSHHRPEKEAHSAAHPQAVXGE DWSADPGTHRLTAFLETKTVWHPTGALGASGSSY" gene complement(23498..24934) /locus_tag="EAO74_RS13355" /old_locus_tag="EAO74_13365" CDS complement(23498..24934) /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Aldedh" /gene_functions="biosynthetic-additional (smcogs) SMCOG1017: aldehyde dehydrogenase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_013001218.1" /locus_tag="EAO74_RS13355" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13365" /product="aldehyde dehydrogenase family protein" /protein_id="WP_099173690.1" /sec_met_domain="Aldedh (E-value: 1.5e-168, bitscore: 558.1, seeds: 89, tool: rule-based-clusters)" /transl_table=11 /translation="MASAFDYAPAPESRSVVDIAPSYGLFIDGEFTEAAEGKVFKTVSP STEEVLSEVAQAGAEDVDRAVKAARRAFEKWSALPGSERAKYLFRIARIIQERSRELAV LETLDNGKPIKETRDADLPLVAAHFFYYAGWADKLDHAGYGANPRPLGVAGQIIPWNFP LLMLAWKIAPALATGNTVVLKPAETTPLSALFFADICRQAGLPKGVVNILTGYGDAGSA LVEHPDVNKVAFTGSTAVGKAIARQIAGTDKKATLELGGKGANIVFDDAPVDQAVEGIV TGIFFNQGQVCCAGSRLLVQESVHDEVLHALKRRLSTLRLGDPLDKNTDIGAINSAEQL ARISALVETGEAEGAERWSAPCELPSSGYWFAPTLFTGVTQAHTVARDEIFGPVLSVLT FRTPDEAVAKANNSQYGLSAGIWTEKGSRILAVANKLRAGVIWANTFNKFDPTSPFGGY KESGFGREGGRHGLEAYLDV" gene complement(24941..25888) /gene="deoC" /locus_tag="EAO74_RS13360" /old_locus_tag="EAO74_13370" CDS complement(24941..25888) /EC_number="4.1.2.4" /GO_component="GO:0005737 - cytoplasm [Evidence IEA]" /GO_function="GO:0004139 - deoxyribose-phosphate aldolase activity [Evidence IEA]" /GO_process="GO:0009264 - deoxyribonucleotide catabolic process [Evidence IEA]" /codon_start=1 /gene="deoC" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_006127095.1" /locus_tag="EAO74_RS13360" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13370" /product="deoxyribose-phosphate aldolase" /protein_id="WP_124275988.1" /transl_table=11 /translation="MPTTAPAFADATASDSALRRFLHGLPGVDTVGLEARAASLGTRSI KTTAKAYAIDLAISMIDLTTLEGADTPGKVRALAAKAVNPDPTDRTTPRTAAVCVYPDM AATAVAALTGSGVKVASVATAFPAGRAALDVKLADVRDAVAAGADEIDMVIDRGAFLSG RYLKVYEEIVAVKAECGSARLKVIFETGELSTYDNIRRASWLGMLAGADFIKTSTGKVG TNATPANTLLMLEAVRDFREQTGVQIGVKPAGGIRTTKDAIKFLVLVNETAGEDWLDNH WFRFGASSLLNDLLMQRQKLSTGRYSGPDYVTVD" gene 26014..26652 /locus_tag="EAO74_RS13365" /old_locus_tag="EAO74_13375" CDS 26014..26652 /GO_function="GO:0005515 - protein binding [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015578488.1" /locus_tag="EAO74_RS13365" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13375" /product="PH domain-containing protein" /protein_id="WP_124274370.1" /transl_table=11 /translation="MTSPTPPAEPAHADRTYRSGAGLVSGALLILLVGWIGGDAVVQGK GWVPWLALAALLMVIPLIVAFTLRPAVFADKERLRIRNPFRTVVLPWTDVSTVRAAYSS EVFTHSGEKYQLWAVPVSLRERKRAARKAGQQAHDDPYGRTSVHADVRDSQARAAAADR TVEDLRELAEGATARKEPSTVTASVRWAYEVIAPAAVGAVLLVVLLAIG" gene complement(26740..27207) /locus_tag="EAO74_RS13370" /old_locus_tag="EAO74_13380" CDS complement(26740..27207) /codon_start=1 /inference="COORDINATES: ab initio prediction:GeneMarkS-2+" /locus_tag="EAO74_RS13370" /note="Derived by automated computational analysis using gene prediction method: GeneMarkS-2+." /old_locus_tag="EAO74_13380" /product="hypothetical protein" /protein_id="WP_241195088.1" /transl_table=11 /translation="MRTVLRSTAVTLMAGGALFFTMSNPAAAAENNTGVVGGSPGSTST CIATIKGAKACFQRYGDLIWTKDTSADGYSVYTNWTNQLKQPSGTWKTYRTGKCSNPGS SGDNASCNKDFYESSSTNAYGGKGSRIQVSACVASFGDDECQTTTWINNDS" gene complement(27377..29017) /locus_tag="EAO74_RS13375" /old_locus_tag="EAO74_13385" CDS complement(27377..29017) /EC_number="5.4.2.-" /GO_function="GO:0016868 - intramolecular phosphotransferase activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018490989.1" /locus_tag="EAO74_RS13375" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13385" /product="phospho-sugar mutase" /protein_id="WP_147983692.1" /transl_table=11 /translation="MQQDLITQARTWLAEDPDPETRAELAGLIDAGDLPALADRFAGTL QFGTAGLRGEIGAGPMRMNRSVVIRAAAGLAAYLKAQGEGGGLVVIGYDARYKSADFAR DTAAVMTGAGLRAAVLPRPLPTPVLAYAVRHLGAVAGVEVTASHNPPRDNGYKVYLGDG SQIVPPADVEIAAAIAAVGPLDGVPRPEGGWEVLGDEVLAAYLARTDAVLSPGSPRTAR TVHTAMHGVGTSVLTAAFARAGFPAPVLVAEQADPDPAFPTVAFPNPEEPGAMDLAFAT ARRADPDIVIANDPDADRCAVAVPDPSAEGGWRMLRGDEVGALLAAHLVDRGVTGVLAE SIVSSSLLGRIAEKAGLGYEETLTGFKWIARVEGLRYGYEEALGYCVDPEGVRDKDGIT AALLITELASVLKEQGRTLLDLLDDLALEHGLHATDQLSVRVEDLTVIANAMRRLRETP PTALAGLPVTSAEDLSQGTDALPPTDGLRYQLTGARVIVRPSGTEPKLKCYLEVVVPVP ARDGLPEAHAKGAELLAAIKRDLAAAAGI" gene complement(29159..29983) /locus_tag="EAO74_RS13380" /old_locus_tag="EAO74_13390" CDS complement(29159..29983) /EC_number="2.4.2.1" /GO_function="GO:0004731 - purine-nucleoside phosphorylase activity [Evidence IEA]" /GO_process="GO:0006139 - nucleobase-containing compound metabolic process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_019527744.1" /locus_tag="EAO74_RS13380" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13390" /product="purine-nucleoside phosphorylase" /protein_id="WP_099173681.1" /transl_table=11 /translation="MNASVIPDHIQGDPHAAAADAAARLRELTGADTHDVALVMGSGWA PAGDALGIPEAEFPVTALPGFPAPAVEGHGGTIRSYRIGEKRALVFLGRTHYYEGRGVA AVAHGVRTAVAAGCGTVILTNGCGGLREGMRPGQPVLISDHINLTAASPIVGANFVDLT DLYSPRLRALCKEIDGTLEEGVYVQFPGPHYETPAEIGMVRVMGGDLVGMSTVLEAIAA REAGAEVLGISLVTNLAAGLSGEPLNHEEVLQAGRDSATRMGALLARVLDRI" gene complement(30100..30537) /locus_tag="EAO74_RS13385" /old_locus_tag="EAO74_13395" CDS complement(30100..30537) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003948359.1" /locus_tag="EAO74_RS13385" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13395" /product="gamma-glutamylcyclotransferase" /protein_id="WP_033297850.1" /transl_table=11 /translation="MSLYAAYAGNLDARLMTRRAPHSPLRGTGWLNGWRLTFGGEQMGW EGALATVVEAPRSQVFVALYDLAPMDEDSMDRWEGVGLDIYRRMRVRVHTLDGEEPAWM YVLNGYEGGLPSARYLGEVADAAESAGAPHDYVMNLRKRPC" gene 30802..32241 /locus_tag="EAO74_RS13390" /old_locus_tag="EAO74_13400" CDS 30802..32241 /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /GO_function="GO:0050660 - flavin adenine dinucleotide binding [Evidence IEA]" /GO_process="GO:0045454 - cell redox homeostasis [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Pyr_redox_2" /gene_functions="biosynthetic-additional (smcogs) SMCOG1175: pyridine nucleotide-disulfide oxidoreductase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015035775.1" /locus_tag="EAO74_RS13390" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13400" /product="NAD(P)H-quinone dehydrogenase" /protein_id="WP_124274372.1" /sec_met_domain="Pyr_redox_2 (E-value: 6.4e-57, bitscore: 190.0, seeds: 64, tool: rule-based-clusters)" /transl_table=11 /translation="MTRIVIIGGGPGGYEAALVGAQLGAEVTVVDCDGLGGASVLTDCV PSKTLIATAEVMTTFDSSYEELGIIVADDTPHMEQAARVVGVDLGKVNRRVKRLALAQS HDITASVTRAGARVMRGRGRLDGLQAADGSRQVVVTAADGTEERLTADAVLIATGGHPR EIPDALPDGERILNWTQVYDLDELPEELIVVGSGVTGAEFAGAYQALGSRVTLVSSRDR VLPGEDPDAAAVLEDVFRRRGMNVMARSRAQSAKRVGDRVEVTLADGRVISGTHCLMAV GAIPNTAGMGLEESGVQLKESGHIRTDRVSRTSAPGVYAAGDVTGIFALASVAAMQGRI AMYHFLGDAVAPLNLKTVSANVFTDPEIATVGYSQADVDSGKIDARVVKLPLLRNPRAK MQGIRDGFVKIFCRPGTGIVVGGCVVAPRASELIHPISLAVDNNLTVEQIANAFTVYPS LSGSIAEVARQLHTRKTAGEA" misc_feature 32297..32314 /note="TFBS match to ArcA, Repressor of carbon oxidation, confidence: weak, score: 15.09" /tool="antismash" gene 32365..33333 /locus_tag="EAO74_RS13395" /old_locus_tag="EAO74_13405" CDS 32365..33333 /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003966754.1" /locus_tag="EAO74_RS13395" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13405" /product="DeoR/GlpR family DNA-binding transcription regulator" /protein_id="WP_124274373.1" /transl_table=11 /translation="MFAAERRQLILEMVRANGAVSLRELARVVQTSEVTVRRDVRALEA EGLLDRRHGGAVLPGGFTRESGFPQKSHLSTAEKTAIADLAAGLVGEGEAIVVGAGTTT QELARRLARVPGLTVVTNSLLVAQALAHANRVEVVMTGGTLRGSNYALVGSGAEQSLQG LRVSRAFLSGSGLTAERGLSTSNMLSASVDRALVQAAAEVVVLADHTKLGSDTMFQTVP TELITRLVTDEPPAHDERAATELQALADQGVEITVAGPDADSGPGEPLPQGRQGRQEMP LPGQRRTQGGHGGPAGLGPQLRSAAALADGPVGRVADLRRR" gene complement(33554..34096) /locus_tag="EAO74_RS13400" /old_locus_tag="EAO74_13410" CDS complement(33554..34096) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1057: TetR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018519115.1" /locus_tag="EAO74_RS13400" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13410" /product="TetR/AcrR family transcriptional regulator" /protein_id="WP_261988317.1" /transl_table=11 /translation="MLGEARTSFAAQGTDASLEDIARRAGVGIGTLYRHFPNRQALMNA VFQEALTSLLARSHELARSDKPCTALVEWLGAIVTHAGAYRGLAQALMSAPGDATSALT SCHVPLRQAGDRLLTRAQSSGSVRADVSIDDLLQLTNAIALAAEQTPADPDLADRLLRL TLRGLRADPVPSARPGD" gene complement(34246..>34827) /locus_tag="EAO74_RS13405" /old_locus_tag="EAO74_13415" /pseudo="" CDS complement(34246..>34827) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003948354.1" /locus_tag="EAO74_RS13405" /note="incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13415" /product="biotin/lipoyl-containing protein" /pseudo="" /transl_table=11 /translation="TRQQALQRAARALAEFQVEGMATAIPFHRAVVADPAFTADPFTIH TRWIETEFVNDITPYTVPADTDTDEEAGRETVVVEVGGKRLEVSLPSSLGMSLARTGLA AGAKPKRRAAKKSGSAASGDTLASPMQGTIVKIAVEEGQEVKEGDLIVVLEAMKMEQPL NAHRSGTVKGLAAEVGTSVSSGAAICEIKD" gene complement(35001..36305) /locus_tag="EAO74_RS13410" /old_locus_tag="EAO74_13420" CDS complement(35001..36305) /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (67-403). E-value: 2e-33. Score: 107.8. Matches aSDomain: nrpspksdomains_EAO74_RS13410_PKS_KS.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) T2PKS: t2clf" /gene_functions="biosynthetic-additional (rule-based-clusters) ketoacyl-synt" /gene_functions="biosynthetic-additional (smcogs) SMCOG1093: Beta-ketoacyl synthase" /gene_functions="biosynthetic-additional (t2pks) CLF 8|9 (Score: 704.7; E-value: 6.6e-215)" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018511393.1" /locus_tag="EAO74_RS13410" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13420" /product="ketosynthase chain-length factor" /protein_id="WP_147983694.1" /sec_met_domain="ketoacyl-synt (E-value: 4.3e-47, bitscore: 157.8, seeds: 77, tool: rule-based-clusters)" /sec_met_domain="t2clf (E-value: 4.6e-208, bitscore: 687.8, seeds: 26, tool: rule-based-clusters)" /transl_table=11 /translation="MTTSVVVTGLGITAPTGLGTRDYWVATRAGKNGIGRVTRFDASSY PATLAGEVPGFAAEELLPSRMLPQTDRMTRLALVAAQWALDDAGVDPKELAEYDMGVVT ASSSGGFEFGQNELQKLWSQGSQYVSAYQSFAWFYAVNSGQISISNGLKGPSGVIVSDE AGGLDALAQGRRLIRKGTRMIVSGGVDASICPWGWVAQLAAKRLTTSDEPARAFLPFDA EASGYVPGEGGAILIMESAESAHERGARVYGEVCGYGATFDAAPGSGREPGLRKAIEFA LDDAGVRPEDVDVVFADAAGVPELDRVEAQALAEVFGERGVPVTAPKTMTGRLYSGAAP LDVATALLAIEEGLIPPTVNSRPADEYGIDLVTEHPRTADVRTALVVARGYGGFNSAVV VRAADXPPHPENRPPPTVSSPPAGGGRLFPRTYVP" aSDomain complement(35097..36104) /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EAO74_RS13410_PKS_KS.1" /domain_subtypes="Iterative-KS" /evalue="2.00E-33" /label="EAO74_RS13410_PKS_KS.1" /locus_tag="EAO74_RS13410" /protein_end="403" /protein_start="67" /score="107.8" /tool="antismash" /translation="PQTDRMTRLALVAAQWALDDAGVDPKELAEYDMGVVTASSSGGFE FGQNELQKLWSQGSQYVSAYQSFAWFYAVNSGQISISNGLKGPSGVIVSDEAGGLDALA QGRRLIRKGTRMIVSGGVDASICPWGWVAQLAAKRLTTSDEPARAFLPFDAEASGYVPG EGGAILIMESAESAHERGARVYGEVCGYGATFDAAPGSGREPGLRKAIEFALDDAGVRP EDVDVVFADAAGVPELDRVEAQALAEVFGERGVPVTAPKTMTGRLYSGAAPLDVATALL AIEEGLIPPTVNSRPADEYGIDLVTEHPRTADVRTALVVARGYGGFNSAVVVRAA" CDS_motif complement(35610..35648) /aSTool="nrps_pks_domains" /database="abmotifs" /detection="hmmscan" /domain_id="nrpspksmotif_EAO74_RS13410_0001" /evalue="2.30E-04" /label="PKSI-KS_m4" /locus_tag="EAO74_RS13410" /protein_end="232" /protein_start="219" /score="14.2" /tool="antismash" /translation="FDAEASGYVPGEG" gene complement(36302..37573) /locus_tag="EAO74_RS13415" /old_locus_tag="EAO74_13425" CDS complement(36302..37573) /EC_number="2.3.1.-" /NRPS_PKS="Domain: PKS_KS(Iterative-KS) (6-397). E-value: 1.7e-52. Score: 170.7. Matches aSDomain: nrpspksdomains_EAO74_RS13415_PKS_KS.1" /codon_start=1 /gene_functions="biosynthetic (rule-based-clusters) T2PKS: t2ks" /gene_functions="biosynthetic-additional (rule-based-clusters) ketoacyl-synt" /gene_functions="biosynthetic-additional (smcogs) SMCOG1022: Beta-ketoacyl synthase" /gene_functions="biosynthetic-additional (t2pks) KS (Score: 787.1; E-value: 8.2e-240)" /gene_kind="biosynthetic" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018960005.1" /locus_tag="EAO74_RS13415" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13425" /product="beta-ketoacyl-[acyl-carrier-protein] synthase family protein" /protein_id="WP_099177864.1" /sec_met_domain="t2ks (E-value: 7e-249, bitscore: 822.8, seeds: 25, tool: rule-based-clusters)" /sec_met_domain="ketoacyl-synt (E-value: 3.6e-53, bitscore: 177.7, seeds: 77, tool: rule-based-clusters)" /transl_table=11 /translation="MNGRRVVITGIEVLAPGGVGAKAFWDLLSDGRTATRGITFFDPSP FRSRVAAEIDFDPREHGLGPQEIRRMDRAAQFAVVAARGAVADSGIDLAAYDPYRVGVT IGSAVGATMGLDEEYNVVSDGGRLHLVDHEYAVPHLYNYLVPSSFTAEVAWAVGAQGPS TVVSTGCTSGIDSVGHAVDLLREGSVDVMIAGSSDAPISPITMACFDAIKATTPRHDDP EHASRPFDSSRNGFVLGEGSAVFVLEELESAKKRGAHIYAEIAGYATRSNAYHMTGLRQ DGKEMAEAIGAALCEARVNATEIDYINAHGSGTKQNDRHETAAFKRSLGDHAYRTPVSS IKSMVGHSLGAIGSIEIAASALAMEHNVVPPTANLHTPDPECDLDYVPLVAREQLTDAV LTVGSGFGGFQSAMVLARPERSAA" aSDomain complement(36383..37555) /ASF="found active site cysteine: True, scaffold matched GSSS: False" /ASF="found active site histidines: True" /aSDomain="PKS_KS" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EAO74_RS13415_PKS_KS.1" /domain_subtypes="Iterative-KS" /evalue="1.70E-52" /label="EAO74_RS13415_PKS_KS.1" /locus_tag="EAO74_RS13415" /protein_end="397" /protein_start="6" /score="170.7" /tool="antismash" /translation="VITGIEVLAPGGVGAKAFWDLLSDGRTATRGITFFDPSPFRSRVA AEIDFDPREHGLGPQEIRRMDRAAQFAVVAARGAVADSGIDLAAYDPYRVGVTIGSAVG ATMGLDEEYNVVSDGGRLHLVDHEYAVPHLYNYLVPSSFTAEVAWAVGAQGPSTVVSTG CTSGIDSVGHAVDLLREGSVDVMIAGSSDAPISPITMACFDAIKATTPRHDDPEHASRP FDSSRNGFVLGEGSAVFVLEELESAKKRGAHIYAEIAGYATRSNAYHMTGLRQDGKEMA EAIGAALCEARVNATEIDYINAHGSGTKQNDRHETAAFKRSLGDHAYRTPVSSIKSMVG HSLGAIGSIEIAASALAMEHNVVPPTANLHTPDPECDLDYVPLVAREQLTD" gene complement(37570..37899) /locus_tag="EAO74_RS13420" /old_locus_tag="EAO74_13430" CDS complement(37570..37899) /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1225: Polyketide synthesis cyclase" /gene_functions="biosynthetic-additional (t2pks) CYC C4-C17/C2-C19 (Score: 185.3; E-value: 2.5e-57)" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018383120.1" /locus_tag="EAO74_RS13420" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13430" /product="TcmI family type II polyketide cyclase" /protein_id="WP_099177865.1" /transl_table=11 /translation="MHSTLIVARMDTASSIDVAKIFRDFDDTEMPHRMGTRRRQLFEYR GLYFHLQDFDEDQGGRQIQEARHDHRFQQISEDLKPLIEAYDPATWRSPADAMAKRFYS WEASA" gene complement(38035..>38925) /locus_tag="EAO74_RS13425" /old_locus_tag="EAO74_13435" /pseudo="" CDS complement(38035..>38925) /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1090: acetyl-CoA carboxylase biotin carboxylase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003948354.1" /locus_tag="EAO74_RS13425" /note="incomplete; partial in the middle of a contig; missing N-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13435" /product="biotin/lipoyl-containing protein" /pseudo="" /transl_table=11 /translation="NTRLQVEHPVTEEVTGLDLVREMFRIADGEELGYGDPAVRGHSFE FRINGEDPGRGFLPAPGTVTLFAPPTGPGVRLDAGVESGSVIGPAWDSLLAKLVVTGAT RQQALQRAARALAEFXVEGMATAIPFHRAVVADPAFTADPFTIHTRWIETEFVNDITPY TVPADTDTDEEAGRETVVVEVGGKRLEVSLPSSLGMSLARTGLAAGAKPKRRAAKKSGS AASGDTLASPMQGTIVKIAVEEGQEVKEGDLIVVLEAMKMEQPLNAHRSGTVKGLSAEV GTSISSGAAVCDIKD" gene 39050..>39103 /locus_tag="EAO74_RS39465" /pseudo="" CDS 39050..>39103 /codon_start=1 /inference="COORDINATES: protein motif:HMM:NF012510.5" /locus_tag="EAO74_RS39465" /note="incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /product="hypothetical protein" /pseudo="" /transl_table=11 /translation="MAKVLQAAKDSGADAVHP" gene complement(<39086..>39895) /locus_tag="EAO74_RS13430" /old_locus_tag="EAO74_13440" /pseudo="" CDS complement(<39086..39895) /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) ATP-grasp" /gene_functions="biosynthetic-additional (smcogs) SMCOG1090: acetyl-CoA carboxylase biotin carboxylase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003948354.1" /locus_tag="EAO74_RS13430" /note="incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13440" /product="biotin carboxylase N-terminal domain-containing protein" /pseudo="" /sec_met_domain="ATP-grasp (E-value: 1.7e-09, bitscore: 34.5, seeds: 20, tool: rule-based-clusters)" /transl_table=11 /translation="MEAFALGGDTPAASYLDMAKVLQAAKDSGADAVHPGYGFLSENAE FAQAVLDAGLTWIGPPPHAIRDLGDKVAARHIAQRAGAPLVAGTPDPVSGSAEVVAFAQ ENGLPIAIKAAFGGGGRGLKVARTLEEIPELYDSAVREAVAAFGRGECFVERYLDKPRH VETQCLADTHGNVVVVSTRDCSLQRRHQKLVEEAPAPFLSKDQNEQLYAASKAILKDAG YVGAGTVEFLVGADGTISFLEVNTRLQHRLRELRVLRQEAIPGVDRVR" gene complement(<39897..40199) /locus_tag="EAO74_RS38510" /old_locus_tag="EAO74_13445" /pseudo="" CDS complement(<39897..40199) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018528099.1" /locus_tag="EAO74_RS38510" /note="incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13445" /product="biotin carboxylase N-terminal domain-containing protein" /pseudo="" /transl_table=11 /translation="MRKVLIANRGEIAVRVARACRDAGIGSVAVYADPDRDALHVRAAD EAFALGGDTPAASYLDMAKVLQAAKDSGADAVHPGYGFLSENAEFAQAVLDAGLTW" misc_feature 40170..40184 /note="TFBS match to MexT, Global virulence regulator, confidence: weak, score: 16.4" /tool="antismash" gene 40578..41018 /locus_tag="EAO74_RS13440" /old_locus_tag="EAO74_13450" CDS 40578..41018 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154419.1" /locus_tag="EAO74_RS13440" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13450" /product="hypothetical protein" /protein_id="WP_187281812.1" /transl_table=11 /translation="MVRRPVAVVTAIVLFVEAVGIVLVNGVLATVADNQSMSLAGMDPD AMVTGTWVMGGVSGALLVLCGLIPLLAGIRDRAPGRLGRIALIACAVVHGVLGALAVGL IGWAAFAFLMVVLALIVLTLVAFDRREPEEAKTGPGAAPEPV" gene complement(41041..41652) /locus_tag="EAO74_RS13445" /old_locus_tag="EAO74_13455" CDS complement(41041..41652) /EC_number="3.6.1.-" /GO_function="GO:0000166 - nucleotide binding [Evidence IEA]" /GO_function="GO:0047429 - nucleoside triphosphate diphosphatase activity [Evidence IEA]" /GO_process="GO:0009146 - purine nucleoside triphosphate catabolic process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_007458826.1" /locus_tag="EAO74_RS13445" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13455" /product="nucleoside triphosphate pyrophosphatase" /protein_id="WP_147983695.1" /transl_table=11 /translation="MAGMTDQRRLVLASASPARLGLLRQAGFAPEVIVSGVDEDALTAP TPGELALVLAEAKAAAVAARPEASGALVIGCDSVLELDGEALGKPADSEEATARWKSMR GRSGILQTGHSVIDTGTGRTASATASTVVRFGEPTDAEVAAYVASGEPLHVAGAFTLDG RSAPFVESIEGSHGNVIGLSLPLLRRLLGELGVSVTDLWV" gene complement(41675..41803) /gene="mmpB" /locus_tag="EAO74_RS38515" CDS complement(41675..41803) /codon_start=1 /gene="mmpB" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047983.1" /locus_tag="EAO74_RS38515" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /product="morphogenic membrane protein MmpB" /protein_id="WP_099174806.1" /transl_table=11 /translation="MLWSDPENKPPKELRDAQDMMRRAGLLLALAMVVAMFVLGTR" gene complement(41874..42080) /locus_tag="EAO74_RS13450" /old_locus_tag="EAO74_13460" CDS complement(41874..42080) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003966748.1" /locus_tag="EAO74_RS13450" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13460" /product="acyl-CoA carboxylase subunit epsilon" /protein_id="WP_099174805.1" /transl_table=11 /translation="MIKVVRGNPTPEELAAALAVVRARAAAVTAEPSGAPLPPEQWSDP GRIARRGALRPGPRSWARTYWPS" gene complement(42096..43676) /locus_tag="EAO74_RS13455" /old_locus_tag="EAO74_13465" CDS complement(42096..43676) /EC_number="6.-.-.-" /GO_function="GO:0016874 - ligase activity [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1059: acetyl-CoA carboxylase, carboxyl transferase," /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010071926.1" /locus_tag="EAO74_RS13455" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13465" /product="acyl-CoA carboxylase subunit beta" /protein_id="WP_124274376.1" /transl_table=11 /translation="MSEPQSDIHTTAGKIADLQRRIEEATHAGSARAVEKQHAKGKLTA RERVDLLLDEGSFVELDEFARHRSTNFGIEKNRPYGDGVVTGYGTVDGRPVCVYSQDFT IFGGSLGEVYGEKIVKVMDFAMKTGCPVIGINDGGGARIQEGVAALGLFAEIFRRNVHA SGVIPQISLIVGPCAGGAVYSPAITDFTVMVDQTSHMFITGPDVIKTVTGEDVGFEELG GARTHNTTSGVAHHMAGDEKDAIEYVKSLLSYLPSNNLSEAPAFPEEADLETTDEDREL DTLIPDSANQPYDMHSAIEHVLDDGEFLETQALFAPNIVTGFGRIEGYPVGIVANQPMQ LAGCLDIDASEKASRFVRTCDAFNVPVITFVDVPGFLPGVDQEYGGIIRRGAKLIYAYA EATVPLITVITRKAFGGAYDVMGSKHLGADLNLAWPTAQIAVMGAQGAVNILHRRTIAA AEDQDATRAELMADYEDALLNPYVAAERGYVDAVIMPSDTRAHLVKGLRQLRTKRESLP PKKHGNIPL" gene 43845..44714 /locus_tag="EAO74_RS13460" /old_locus_tag="EAO74_13470" CDS 43845..44714 /EC_number="6.3.4.15" /GO_function="GO:0004077 - biotin--[biotin carboxyl-carrier protein] ligase activity [Evidence IEA]" /GO_process="GO:0036211 - protein modification process [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003966746.1" /locus_tag="EAO74_RS13460" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13470" /product="biotin--[acetyl-CoA-carboxylase] ligase" /protein_id="WP_147983696.1" /transl_table=11 /translation="MTPPDAPHNRWSDLDRPPLNATALRRGLLKPEGLWTSLDIVEATG STNTDLVARASGGGLAEGAVLVAEEQTAGRGRLDRSWTAPPRSGLFLSVYLTPGDVPAE RWGWLPLLAGVAAATGLAQSAGVDMALKWPNDLLVTIGGTERKTGGILAERAGDGVVVG IGLNVSLRAAELPAPHAGSLALAGAVSTDRETLLRAVLRSLEQWYVQWRDANGDAAESG LQAAYAAGCATLDRTVRAELPGDRTLVGEAVAIDGDGRLVLATGDGLQEPVSAGDIVHL RGEEGGLT" misc_feature complement(44793..44808) /note="TFBS match to CRP, Cyclic AMP receptor protein, confidence: weak, score: 15.8" /tool="antismash" gene 44882..46072 /locus_tag="EAO74_RS13465" /old_locus_tag="EAO74_13475" CDS 44882..46072 /EC_number="2.7.7.-" /GO_process="GO:0009190 - cyclic nucleotide biosynthetic process [Evidence IEA]" /GO_process="GO:0035556 - intracellular signal transduction [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154413.1" /locus_tag="EAO74_RS13465" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13475" /product="adenylate/guanylate cyclase domain-containing protein" /protein_id="WP_124274378.1" /transl_table=11 /translation="MTVDDTNSDDGAEPSSGPSVHSTPHHEVDHTAEPTDDPLAIRLEQ LILGADRRYTPFQAARTAGVSMDLASRFWRAMGFADIGQAKALTEADVLALRRLAGLVE AGLLSEPMAIQVARSTGQTTARLAEWQIDSFLAGLTEPPEPGMTRTEVTYPLIELLLPE LQEFLVYVWRRQLAAATGRVVQTGDDEEMVDRRLAVGFADLVGFTRLTRRLEEEELGEL VEAFETTSADLVAAHGGRLIKTLGDEVLFAADDAGTAGEIALRLVEVMAQDTTMPSLRV GIAFGTVTTRMGDVFGTTVNLASRLTSIAPKDAVLVDGAFAAELIRNGDAPASEAEETA AAAERARLAEKEDRRPDEEPPHPSYRFGLQPMWQRPVRGLGVVEPWLLARRGKPST" gene 46140..46952 /locus_tag="EAO74_RS13470" /old_locus_tag="EAO74_13480" CDS 46140..46952 /NRPS_PKS="Domain: ECH (18-262). E-value: 3.8e-63. Score: 205.0. Matches aSDomain: nrpspksdomains_EAO74_RS13470_ECH.1" /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1023: enoyl-CoA hydratase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_012379328.1" /locus_tag="EAO74_RS13470" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13480" /product="enoyl-CoA hydratase/isomerase family protein" /protein_id="WP_124274379.1" /transl_table=11 /translation="MGVTSEQRFGEFVVVRRHEGQDHVAELVLDRPEAMNAVSTAMARS VAEACAALAADQGVRATVLTSSHERAFCVGADLKERNSFTDAELVRQRPTARAAYTGVL ELPMPVVAAVHGFALGGGFELALACDVIVADRTAVVGLPEVSVGVIPGGGGTQLLPRRI GAARAAELVFTARRVEAAEARELGLVDELVEAGRDREEALALGARIAANSPVGLRAAKR ALRLGQGLDLRAGLEVEDAAWRSVAFSGDRAEGVAAFNEKRKPSWPGE" aSDomain 46194..46925 /aSDomain="ECH" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EAO74_RS13470_ECH.1" /evalue="3.80E-63" /label="EAO74_RS13470_ECH.1" /locus_tag="EAO74_RS13470" /protein_end="262" /protein_start="18" /score="205.0" /tool="antismash" /translation="EGQDHVAELVLDRPEAMNAVSTAMARSVAEACAALAADQGVRATV LTSSHERAFCVGADLKERNSFTDAELVRQRPTARAAYTGVLELPMPVVAAVHGFALGGG FELALACDVIVADRTAVVGLPEVSVGVIPGGGGTQLLPRRIGAARAAELVFTARRVEAA EARELGLVDELVEAGRDREEALALGARIAANSPVGLRAAKRALRLGQGLDLRAGLEVED AAWRSVAFSGDRAEGVAAFNEK" gene 47040..48206 /locus_tag="EAO74_RS13475" /old_locus_tag="EAO74_13485" CDS 47040..48206 /codon_start=1 /gene_functions="biosynthetic-additional (smcogs) SMCOG1025: diguanylate cyclase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154411.1" /locus_tag="EAO74_RS13475" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13485" /product="GGDEF domain-containing protein" /protein_id="WP_147983697.1" /transl_table=11 /translation="MGGDDARLRAVVALAQTMAAAYTPHESWHAAAMGACEALGGSFAA LSVWERDQGRLRVLVNAGERAEGEEEFPEDEAYPVHQFPEITEFLHERWAGGGEPDAWV ETAAGAPAAGAPARGARPYCHQRVAALRRRGRGCCVVAPIVLHGRAWGELYVARPAGAP VFDRDDADFATVLAAVVAAGIAQTERLEEVRKLAFTDPLTGLANRRAVDLRLDEAVDRY RTEGAVVSLVVCDLNGLKTVNDTHGHAVGDRLLERFGSVLSLCGAMLPGALAARLGGDE FCLLAVGPPADDVVRVSEELCARAVALEPGDGVACGVASTGDDIGPVQSARRLFRLADA AQYQAKAARSRRPVVAGRDGDVIRLADSPPRSPHDRRRLRGNPPGGDR" misc_feature 48257..48271 /note="TFBS match to SypG, Regulator of biofilm formation and host colonization, confidence: weak, score: 17.21" /tool="antismash" misc_feature 48263..48281 /note="TFBS match to LexA_variant_3, Repressor of DNA damage response, confidence: weak, score: 19.54" /tool="antismash" misc_feature complement(48264..48282) /note="TFBS match to LexA_variant_3, Repressor of DNA damage response, confidence: weak, score: 21.36" /tool="antismash" gene 48265..49815 /gene="hutH" /locus_tag="EAO74_RS13480" /old_locus_tag="EAO74_13490" CDS 48265..49815 /EC_number="4.3.1.3" /GO_component="GO:0005737 - cytoplasm [Evidence IEA]" /GO_function="GO:0004397 - histidine ammonia-lyase activity [Evidence IEA]" /GO_process="GO:0006548 - L-histidine catabolic process [Evidence IEA]" /codon_start=1 /gene="hutH" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010058511.1" /locus_tag="EAO74_RS13480" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13490" /product="histidine ammonia-lyase" /protein_id="WP_147983698.1" /transl_table=11 /translation="MDMHTVVVGTSGTTAEDVVAVARRGARVELSPAAVEALAAAREIV DALAAKPEPVYGVSTGFGALASRHISPDLRAQLQRNIVRSHAAGMGPHVEREVVRALMF LRLKTLASGHTGVRPEVAQTMADVLNAGITPVVHEYGSLGCSGDLAPLSHCALTLMGEG DAEGPDGVVRPAGELLAAHGITPVELREKEGLALLNGTDGMLGMLVMALADLRNLYTSA DITAALSLEALLGTDRVLAPELHAIRPHPGQGVSADNMLRVLAGSGLTGHHQDDAPRVQ DAYSVRCAPQVNGAGRDTLTHGALVADRELASAVDNPVVLPDGRVESNGNFHGAPVAYV LDFLAIVAADLGSITERRTDRLLDKNRSHGLPPFLADDAGVDSGLMIAQYTQAALVSEL KRLAVPASVDSIPSSAMQEDHVSMGWSAARKLRTAVTNLARIVAVELYAATRAVELRAA EGLTPGPAAQAVIGALRAAGVQGPGPDRFLSPDLEAADAFVREGKLVAAVETVTGPLA" gene complement(49878..50198) /locus_tag="EAO74_RS13485" /old_locus_tag="EAO74_13495" CDS complement(49878..50198) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047991.1" /locus_tag="EAO74_RS13485" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13495" /product="hypothetical protein" /protein_id="WP_124274382.1" /transl_table=11 /translation="MSIARRTLLTTTAAGTLLCALWFVPSANATGGTGAPSGSAGSSAG SSTEVRQASATGEFTSQETLADTGTGIDTTPYLIGGTASLCVGAGFVVYSMRRGSAQGT GF" gene 50367..50768 /locus_tag="EAO74_RS13490" /old_locus_tag="EAO74_13500" CDS 50367..50768 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047992.1" /locus_tag="EAO74_RS13490" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13500" /product="hypothetical protein" /protein_id="WP_124274383.1" /transl_table=11 /translation="MSTSETPSFVRLRVEMVLEISDADALTGTALESIAADFTTTGASA DESAEERTHAEETVREDAAEALASLIDPFDLVSQVPGVELAQASWSSETIDYDPDAEDW TAGEDGDEAYYGIEDNETDDEEGGGNTER" gene 50950..52215 /locus_tag="EAO74_RS13495" /old_locus_tag="EAO74_13505" CDS 50950..52215 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015610957.1" /locus_tag="EAO74_RS13495" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13505" /product="Ig-like domain-containing protein" /protein_id="WP_124274384.1" /transl_table=11 /translation="MEKLVMTDSKRRRGLMAASALLGGVLVLSACSDDGGDSGASADSS KTSQAQVDEAAAKDASEAQITIAPKNGATNASINNAAMVTVAKGKLTEVTMTSADGDAV EGTLAADGSSWKPSGQLERSTTYKISATAADSKGREAHGNSSFTTVSPENSFIGNFTPE DGSTVGVGMPVSINFNKAITNKKAVQDGIKVTSSSGQEVVGHWFNNQRLDLRPEDYWQG GSTVTLKLALDGVEGADGVVGVQQKTVTFKVGRNQVSTVDAKAHTMTVTRDGKTVKTIP ISAGSSDNPTYNGQMVISEKFKETRMDGSTVGFTDDDGKGEYDIKDVPHAMRLSTSGTF IHGNYWGAKSIFGSANTSHGCVGLSDTQGADDPNTPAAWLYDNSMVGDVVIVKNSPDKT IAPDNGLNGWNMSWSEWTANAA" gene 52384..53853 /locus_tag="EAO74_RS13500" /old_locus_tag="EAO74_13510" CDS 52384..53853 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047994.1" /locus_tag="EAO74_RS13500" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13510" /product="ABC transporter permease" /protein_id="WP_147983699.1" /transl_table=11 /translation="MFFTYLRRELRRRRKAALVVASGLALGIALVIIVSSVSSGMSKAQ DKVLESLYGLGTDMTVTKAAAAPGSGGTERPKFDFDAKDDDEATQSTDRVMVQGFQTLA SSTVDKVGEQDGVVDAVGGLSLTVMKVDGQFKRGEFKQDESASQGGPGGRGGSGGGQPQ GEVQGGGASFDVNSFTVYGTDVTQQDLGPLTSSKITEGRTFKATETDAKVAVVDSAYAK EKELAVGRTVAVSGTTYKIVGVSTADSGDAAANVYIPLKQAQTVADSKDKVTTVYVQAA DSQKIDTVKAAIQKNISGTTVTTSADLADTVSGSLSTASDLASSVGKWLSVAVLIAAFL VAGLLTSSAVSRRVREFGTLKALGWKSGRVTRQVVGEALVNGLMGGVLGIAVGVAGAYV VTAISPTLTAQLGSTGGGGGGMGGGGPMGGGGGGRQTASKTLDIALTAPVSLTTILIAV GLAVAGGLIAGAFGGWRASRLRPADALRRVA" gene 53894..54577 /locus_tag="EAO74_RS13505" /old_locus_tag="EAO74_13515" CDS 53894..54577 /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /GO_function="GO:0016887 - ATP hydrolysis activity [Evidence IEA]" /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1000: ABC transporter ATP-binding protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047995.1" /locus_tag="EAO74_RS13505" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13515" /product="ABC transporter ATP-binding protein" /protein_id="WP_124274386.1" /transl_table=11 /translation="MYQLKGVTKRYMRGKNPVDALAGVDLTIEDGGRLVIQGPTGGGKS TLLQMLGGLDRPTSGTIELDGVDLAKLPESRLTKVRAESIGFVFQSFNLIPTLTAQENV ETALVPLGLGAKIRRERAAEALESVGLGDRPTHLPSEMSGGQQQRVAIARALVKRPKVL LADEPTGNLDESMRDEIMELLDGLWKEHGLTFVMVTHDSSLARKAPRVATIRKGRVTVT ENAAA" gene 54649..55935 /gene="gdhA" /locus_tag="EAO74_RS13510" /old_locus_tag="EAO74_13520" CDS 54649..55935 /EC_number="1.4.1.4" /GO_function="GO:0016639 - oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor [Evidence IEA]" /GO_process="GO:0006520 - amino acid metabolic process [Evidence IEA]" /codon_start=1 /gene="gdhA" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_008747665.1" /locus_tag="EAO74_RS13510" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13520" /product="NADP-specific glutamate dehydrogenase" /protein_id="WP_315985670.1" /transl_table=11 /translation="MRVARGAVREVLETLGPVLAQRPEFVDARIIERICEPERQLIFRV PWADDAGGIHVNRGFRVEFSSSLGPYKGGLRFHPSVNLGIVKFLGFEQIFKNALTGMPI GGGKGGADFDPKGRSDAEVMRFCQSFMTELHRHLGEYTDVPAGDIGVGGREIGYLFGQY KRITNRYESGVLTGKGLGWGGAQARTEATGYGCVLFTAEMLRVRGESLEGQRIAVSGSG NVAIYAIEKAQQLGATVVTCSDSGGYVVDEKGIDLALLKEVKEDGRGRISEYAERRGDH VRYVPGTGVWSVPVDVALPCATQNELHEEDALALVRNGVKAVAEGANMPTTPEAVHVLQ DAGVAFAPGKAANAGGVATSALEMQQNASRDSWTFSHTEERLAEIMRHIHDSCYTTAEK YGSPGNYVVGANIAGFELVADAMLAQGLI" gene complement(55986..56369) /locus_tag="EAO74_RS13515" /old_locus_tag="EAO74_13525" CDS complement(55986..56369) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014047998.1" /locus_tag="EAO74_RS13515" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13525" /product="YrdB family protein" /protein_id="WP_147984393.1" /transl_table=11 /translation="MTANEDHRHLTALRGRPWFAANEALAFVVELVAIGALAVWGFTAP EGVAASVALGIGAPVAAVVLWGLFAAPRARYPLPLAGVLAVKTLVLGGGVAAVHGTGHP VAAVVLAVVTVANTGCAEHFRRR" gene 56538..56912 /locus_tag="EAO74_RS13520" /old_locus_tag="EAO74_13530" CDS 56538..56912 /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020117992.1" /locus_tag="EAO74_RS13520" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13530" /product="helix-turn-helix domain-containing protein" /protein_id="WP_124274388.1" /transl_table=11 /translation="MSSHATGRARVIPLRPVHAAPAPAAAAKEPLWRDVVGDVLRRERT AQRRTLKDVAEAARISMPYLSEIERGRKEASSEVLAAAARSLGLGLADVLSLAQDEIAR RAPSRTAPARAPMGEVRLAA" gene complement(<57057..57380) /locus_tag="EAO74_RS13525" /old_locus_tag="EAO74_13535" /pseudo="" CDS complement(<57057..57380) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_003971863.1" /locus_tag="EAO74_RS13525" /note="incomplete; partial in the middle of a contig; missing C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13535" /product="ClpP family protease" /pseudo="" /transl_table=11 /translation="MGQYTIPNVVERTPQGERSYDVFSRLLSERIIFIGTEIDDGVANV VIAQLLHLESSNPGGEIAVYLNSPGGSFTSLMAIYDTMSFVSAPIATFCVGQAASTAAV LLAG" gene complement(57382..58029) /locus_tag="EAO74_RS13530" /old_locus_tag="EAO74_13540" CDS complement(57382..58029) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016639872.1" /locus_tag="EAO74_RS13530" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13540" /product="ATP-dependent Clp protease proteolytic subunit" /protein_id="WP_147984394.1" /transl_table=11 /translation="MHRVVDGQPRRHRAADEDTPSTRFDDHLAAQLLAQRIVFLGTQVD EVSANRVCAQLLLLSAEDPRTDISLYINSPGGSVTAGLAIYDTMQLIPNDVSTLAMGFA ASMGQFLLTVGTEGKRYALPNARIMMHQPSAGIGGTASDIAIQAENLEFTKQAVERITA AHTGQSAETISRDGDRDRWFTAGQAKEYGMVDHVVESLDDVRPAGSRRRMGL" gene <57985..>58186 /locus_tag="EAO74_RS13535" /old_locus_tag="EAO74_13545" /pseudo="" CDS 57985..>58186 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_008408790.1" /locus_tag="EAO74_RS13535" /note="incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13545" /product="ATP-dependent Clp protease proteolytic subunit" /pseudo="" /transl_table=11 /translation="MGSVTAGLAIYDTMQLIPNDVSTLAMGFAASMGQFLLTVGTEGKR YALPNARIMMHQPSAGIGGTAS" assembly_gap 58187..58286 /estimated_length=100 /gap_type="within scaffold" /linkage_evidence="paired-ends" gene <58287..>58503 /locus_tag="EAO74_RS13540" /old_locus_tag="EAO74_13550" /pseudo="" CDS 58289..>58503 /codon_start=2 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_016639872.1" /locus_tag="EAO74_RS13540" /note="incomplete; partial in the middle of a contig; missing N-terminus and C-terminus; Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13550" /product="ATP-dependent Clp protease proteolytic subunit" /pseudo="" /transl_table=11 /translation="MPRAADEDTPSTRFDDHLAAQLLAQRIVFLGTQVDEVSANRVCAQ LLLLSAEDPRTDISLYINSPGGSVTAG" gene complement(58692..59402) /gene="msrA" /locus_tag="EAO74_RS13545" /old_locus_tag="EAO74_13555" CDS complement(58692..59402) /EC_number="1.8.4.11" /GO_function="GO:0008113 - peptide-methionine (S)-S-oxide reductase activity [Evidence IEA]" /GO_function="GO:0033744 - L-methionine:thioredoxin-disulfide S-oxidoreductase activity [Evidence IEA]" /GO_process="GO:0006979 - response to oxidative stress [Evidence IEA]" /GO_process="GO:0030091 - protein repair [Evidence IEA]" /codon_start=1 /gene="msrA" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014048001.1" /locus_tag="EAO74_RS13545" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13555" /product="peptide-methionine (S)-S-oxide reductase MsrA" /protein_id="WP_124274391.1" /transl_table=11 /translation="MFLTHRTPQLPTPEEALRGRPTPEFTVPSRHTVLGNPLTGPYPQG LEVADFALGCFWGAERKFWQTEGVWTTLVGYQGGYTENPSYEETCSGLTGHTEAVRVVF DPKVVSYADLLKVFWESHNPTQGFRQGNDVGTQYRSALYTHSPEQAEAAQASREAYQQV LTGAGFKEITTEILPAEGRTFWPAEPYHQQYLDKNPDGYCGIGGTGATLESPSETNWGR ACPTGIAPAPSASE" gene complement(59470..59664) /locus_tag="EAO74_RS13550" /old_locus_tag="EAO74_13560" CDS complement(59470..59664) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154398.1" /locus_tag="EAO74_RS13550" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13560" /product="hypothetical protein" /protein_id="WP_124274392.1" /transl_table=11 /translation="MARLIPLILIALAVWFWLRARRKTAAYMASYESPAGGDREAGPDR ATGPDREAGERRDPPAPAA" gene complement(59707..60810) /locus_tag="EAO74_RS13555" /old_locus_tag="EAO74_13565" CDS complement(59707..60810) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010058493.1" /locus_tag="EAO74_RS13555" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13565" /product="hypothetical protein" /protein_id="WP_099174785.1" /transl_table=11 /translation="MEILWFLLAVCMLVAVVGPLMLRRRGGIRQVAPGSPDAADPDTYG FARQEELDVRMPGPDQDLLDVLDVVQGTGSWRAASQLLAGTPKESEIRWQRVQAFAGAA SLELAQRPGAGGAWLRTWRAEAPKDAGAAAVHAEFLVQQAWRTGTVGTDDFRIILEEAR TVCGEAALLAPGDPVPYIVELAVARGLGYSHEEFDQLWAKIIDRAPAHMGAHIAALHFW CEKWHGSREEADRFATTAAARAPQGSLLAALPLFAVYEHLPEVNLVQGFYRGVVVTKAV EGAMFAVHAARADDPMLAHVRHLLVLFLVRMERWSEAMHQLVHIDGHVGALPWTQSSDP AAEYTVYRALAVAGYEANGGSPATLLH" gene 60890..62035 /locus_tag="EAO74_RS13560" /old_locus_tag="EAO74_13570" CDS 60890..62035 /EC_number="2.5.1.48" /GO_function="GO:0030170 - pyridoxal phosphate binding [Evidence IEA]" /GO_process="GO:0019346 - transsulfuration [Evidence IEA]" /NRPS_PKS="Domain: Aminotran_1_2 (53-204). E-value: 1.2e-09. Score: 29.7. Matches aSDomain: nrpspksdomains_EAO74_RS13560_Aminotran_1_2.1" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) DegT_DnrJ_EryC1" /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_1_2" /gene_functions="biosynthetic-additional (rule-based-clusters) Aminotran_5" /gene_functions="biosynthetic-additional (smcogs) SMCOG1168: O-succinylhomoserine sulfhydrylase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018550400.1" /locus_tag="EAO74_RS13560" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13570" /product="cystathionine gamma-synthase" /protein_id="WP_124274394.1" /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 2e-11, bitscore: 40.7, seeds: 38, tool: rule-based-clusters)" /sec_met_domain="Aminotran_1_2 (E-value: 4.4e-08, bitscore: 29.6, seeds: 48, tool: rule-based-clusters)" /sec_met_domain="Aminotran_5 (E-value: 5.3e-06, bitscore: 22.6, seeds: 34, tool: rule-based-clusters)" /transl_table=11 /translation="MSDQHSFETLAIHAGNTADPLTGAVVPPIYQVSTYKQDGVGGLRG GYEYSRSANPTRTALEENLAALEGGRRGLAFASGLAAEDCLLRTLLTPGDHVVIPNDAY GGTFRLFAKVASRWGVEFSVADTSDVSAVRAALTPRTKAIWVETPSNPLLGITDIAAVA GVARQAGVRLVVDNTFASPYLQQPLSLGADVVVHSTTKYMGGHSDVVGGALVVGDPELA EELAYHQNAMGAVAGPFDAWLVLRGIKTLAVRMDRHDANATKVADLLTRHPKVTQVLYP GLPEHPGHEVAAKQMKAFGGMVSFRVAGGEEAAVEVCNRAKLFTLGESLGGVESLIEHP GRMTHASTAGSLLEVPADLVRLSVGIENADDLLADLTQALG" aSDomain 61049..61501 /aSDomain="Aminotran_1_2" /aSTool="nrps_pks_domains" /database="nrpspksdomains.hmm" /detection="hmmscan" /domain_id="nrpspksdomains_EAO74_RS13560_Aminotran_1_2.1" /evalue="1.20E-09" /label="EAO74_RS13560_Aminotran_1_2.1" /locus_tag="EAO74_RS13560" /protein_end="204" /protein_start="53" /score="29.7" /tool="antismash" /translation="NPTRTALEENLAALEGGRRGLAFASGLAAEDCLLRTLLTPGDHVV IPNDAYGGTFRLFAKVASRWGVEFSVADTSDVSAVRAALTPRTKAIWVETPSNPLLGIT DIAAVAGVARQAGVRLVVDNTFASPYLQQPLSLGADVVVHSTTKYMG" gene complement(62095..62286) /locus_tag="EAO74_RS13565" /old_locus_tag="EAO74_13575" CDS complement(62095..62286) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154395.1" /locus_tag="EAO74_RS13565" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13575" /product="DUF1059 domain-containing protein" /protein_id="WP_124274395.1" /transl_table=11 /translation="MTRKIADCRRYPSVMNCTLTISGEEDEVVRAAAEHAVSVHEHTDS PELRDQIRASLEDEKAAV" gene complement(62366..62896) /locus_tag="EAO74_RS13570" /old_locus_tag="EAO74_13580" CDS complement(62366..62896) /GO_function="GO:0003700 - DNA-binding transcription factor activity [Evidence IEA]" /GO_process="GO:0006355 - regulation of DNA-templated transcription [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1135: MarR family transcriptional regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154394.1" /locus_tag="EAO74_RS13570" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13580" /product="MarR family winged helix-turn-helix transcriptional regulator" /protein_id="WP_099174782.1" /transl_table=11 /translation="MPPQDMTTAASPSGGAAPGHPGTDHLLDALQHQVAVFARRAEQTR LGGVGQVRNSMDRAAYLLLNRLDVEGPMGVKALAAGMGIDSSTVTRQVAPLVDTGLVKR TSHPEDGRAVVLQLSPRGQSRLEEVRASRRELMSQVTDGWTEEERDTFCALLTRFNGSL AARQSAHQSAQEN" gene 63054..64283 /gene="ilvA" /locus_tag="EAO74_RS13575" /old_locus_tag="EAO74_13585" CDS 63054..64283 /EC_number="4.3.1.19" /GO_function="GO:0004794 - threonine deaminase activity [Evidence IEA]" /GO_process="GO:0006567 - threonine catabolic process [Evidence IEA]" /codon_start=1 /gene="ilvA" /gene_functions="biosynthetic-additional (rule-based-clusters) PALP" /gene_functions="biosynthetic-additional (smcogs) SMCOG1081: cysteine synthase" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018956087.1" /locus_tag="EAO74_RS13575" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13585" /product="threonine ammonia-lyase" /protein_id="WP_124274396.1" /sec_met_domain="PALP (E-value: 2.3e-84, bitscore: 280.2, seeds: 145, tool: rule-based-clusters)" /transl_table=11 /translation="MSFRTSGPFPPLILDDVRGAQKMLSGVARTTGMEGSRHLSSLVGA PVHLKCENLQRTGSFKLRGAYVRIAGLSPVERAAGVVAASAGNHAQGVALASSLLGVRS TVFMPVGAPLPKVAATREYGAEVRLQGHVVDETLAAAQEYAEQTGAVFIHPFDHPDIIA GQGTVGLEILEQCPEVRTVVVGIGGGGLAAGIAVAVKALRPDVKVVGVQAAGAAAFPPS LSAGHPVALDSVQTMADGIKVGRPGDLTFPLVQELVDEVRTVSEDELSSALLLCLERAK MVVEPAGASPVAALLSDPKAFRGPVVAVLSGGNVDPLLMQRILTHGMVAAGRYLSLRLR LTDRPGALAAMLATLSVADANVLDIQHVRTDPRLGLTEAEVELHLETKGPEHCEEVAAA LRTAGYLVRS" gene 64468..65472 /locus_tag="EAO74_RS13580" /old_locus_tag="EAO74_13590" CDS 64468..65472 /GO_function="GO:0005524 - ATP binding [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1000: ABC transporter ATP-binding protein" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154392.1" /locus_tag="EAO74_RS13580" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13590" /product="ATP-binding cassette domain-containing protein" /protein_id="WP_099174780.1" /transl_table=11 /translation="MPGAIYAEGLVKTFGDVRALDGVDLDVPEGTVLGLLGPNGAGKTT AVRVLTTLIQPDSGQAVVAGIDVLKNPDEVRRSIGLSGQFAAVDEYLTGRENLQMVGQL YQMGARDAKKRAGELLEKFNLADAADRTAKTYSGGMRRRLDLAAALVVSPPVMFMDEPT TGLDPRNRQQLWEVIEELVAGGTTLLLTTQYLEEADHLAHDICVIDHGKVIARGTSDQL KARTGGERVEVVVHRPDEIGPARSVLATYGKGEIAVAEHTRKLTVPVTGGAKLLAEVIR DLDAHGVEIDDIGLRRPTLDDVFISLTGHAAELGKNGENASTEAAEGRKEDGQ" gene 65469..66323 /locus_tag="EAO74_RS13585" /old_locus_tag="EAO74_13595" CDS 65469..66323 /GO_function="GO:0042626 - ATPase-coupled transmembrane transporter activity [Evidence IEA]" /GO_function="GO:0140359 - ABC-type transporter activity [Evidence IEA]" /codon_start=1 /gene_functions="transport (smcogs) SMCOG1065: ABC-2 type transporter" /gene_kind="transport" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154391.1" /locus_tag="EAO74_RS13585" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13595" /product="ABC transporter permease" /protein_id="WP_147983700.1" /transl_table=11 /translation="MTAVTDTPNLPLKNRGALGRSVADSLVVARRNLIRMARIPEMVIF GLVQPIMFVVLFTYVFGGSIKVGGSLSSTAYKEFLMAGIFAQTVTFATAGAGAGIADDM HKGLIDRFRSLPMARGAVLTGRTLADLVQTALTLVVLAGVALIIGWRTHENIGKVLLGF LLLLLLGYAFSWIGAMIGLIVRTPEAATSGGLIWLFPLTFISNAFVDANQMPTVLRHIA EWNPFSATVQACRELFGNLPPGFVTPDAWPMQHPILASVIWSVVIVAVFRTLAVRRYRS ATA" gene complement(66389..66886) /gene="greA" /locus_tag="EAO74_RS13590" /old_locus_tag="EAO74_13600" CDS complement(66389..66886) /GO_function="GO:0003677 - DNA binding [Evidence IEA]" /GO_function="GO:0070063 - RNA polymerase binding [Evidence IEA]" /GO_process="GO:0032784 - regulation of DNA-templated transcription elongation [Evidence IEA]" /codon_start=1 /gene="greA" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_018101005.1" /locus_tag="EAO74_RS13590" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13600" /product="transcription elongation factor GreA" /protein_id="WP_124274399.1" /transl_table=11 /translation="MTQTSDNVTWLTPEAYNQLKAELEYLSGPARTEISVKIAAAREEG DLRENGGYHAAKEEQGKMELRVRQLTQLLEHAKVGEAPADDGVVEPGMVVTIAFDGDPD DTVTFLLASREYASADIETYSPQSPLGTGVNGKRMGETAEYELPNGKKATVKIVSAKPY TG" misc_feature complement(66838..66853) /note="TFBS match to ClgR, Caseinolytic protease gene regulator, confidence: weak, score: 22.62" /tool="antismash" gene complement(67101..67505) /locus_tag="EAO74_RS13595" /old_locus_tag="EAO74_13605" CDS complement(67101..67505) /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154389.1" /locus_tag="EAO74_RS13595" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13605" /product="DUF4307 domain-containing protein" /protein_id="WP_124274400.1" /transl_table=11 /translation="MAAVREALPEGRYGRSQDERADRKLKIIGSVLGVAFLAVIGWFGY AYVAGTDVSAELIKSRIVSDSRAEAHLEVRKDRDADGHCTLRALSEDGGEVGRADFRFD ERSERIDEVVTLRTTSRATAVELKGCASGG" misc_feature 67529..67544 /note="TFBS match to ColR, Phenol-responsive regulator, confidence: weak, score: 17.65" /tool="antismash" gene 67603..68484 /gene="mca" /locus_tag="EAO74_RS13600" /old_locus_tag="EAO74_13610" CDS 67603..68484 /GO_process="GO:0010126 - mycothiol metabolic process [Evidence IEA]" /codon_start=1 /gene="mca" /gene_functions="biosynthetic-additional (rule-based-clusters) PIG-L" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_010045685.1" /locus_tag="EAO74_RS13600" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13610" /product="mycothiol conjugate amidase Mca" /protein_id="WP_124274401.1" /sec_met_domain="PIG-L (E-value: 7.6e-24, bitscore: 81.9, seeds: 137, tool: rule-based-clusters)" /transl_table=11 /translation="MTEQLRLMAVHAHPDDESSKGAATMAKYVSEGVDVLVVTCTGGER GSILNPKLQGDAYIEANIHEVRKKEMDEAREILGVKQEWLGFVDSGLPEGDPLPPLPEG CFALEDDETAAGRLVAKIRAFRPQVITTYDENGGYPHPDHIKTHTISMIAFEGAGDTER FPEAEFGPAWQPQKLYYNQGFNKPRTVALHEALLARGLESPYGDWLERWKQFERAERTL TTHIPCDDFFEIRDKALIAHATQIDPDGGWFRVPMDVQREVWPTEEYELAKSLVDTSLP ESDLFAGIRDNA" gene 68486..68773 /locus_tag="EAO74_RS13605" /old_locus_tag="EAO74_13615" CDS 68486..68773 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_004984056.1" /locus_tag="EAO74_RS13605" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13615" /product="hypothetical protein" /protein_id="WP_124274402.1" /transl_table=11 /translation="MYATQALTQLVPLAADELDKNKVTPGVLGFLVFAALAVGTWLLMK SMNRHMGKVDFEEAPDPAARPGDTDGEPAEASSGAGTKAAGTKATASGKG" gene complement(68828..69487) /locus_tag="EAO74_RS13610" /old_locus_tag="EAO74_13620" CDS complement(68828..69487) /GO_process="GO:0000160 - phosphorelay signal transduction system [Evidence IEA]" /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family DNA-binding response regulator" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_015578514.1" /locus_tag="EAO74_RS13610" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13620" /product="response regulator transcription factor" /protein_id="WP_147983701.1" /transl_table=11 /translation="MRIVIAEDDPLLREGLALLLRAEGLDVVATAGTPDVFLAAVDEHR PDLAIVDVRMPPTHTDEGIRAAVEARRRQPGLAVLVLSAYVEQAFATDLLADGSARLGY LLKERVGRVEEFLTALERVADGGTAIDPEVVAQLFARTRPDTRLDRLSPREREVLALMA EGLGNAAIAERLVVTDGAVHKHIRSIFAKLDLAPADGTDRRVAAVLRHLNDAHRRA" gene complement(69475..70749) /locus_tag="EAO74_RS13615" /old_locus_tag="EAO74_13625" CDS complement(69475..70749) /codon_start=1 /gene_functions="regulatory (smcogs) SMCOG1048: sensor histidine kinase" /gene_kind="regulatory" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154385.1" /locus_tag="EAO74_RS13615" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13625" /product="sensor histidine kinase" /protein_id="WP_187281813.1" /transl_table=11 /translation="MPAHDAPPATAQEPARPWDVFARARTALDAFEHLVGGIGTAILAL ITLLWLVFTAAACLVGVGLFLVPGTLRALRAVAGRERVRLSRWGPEVIGPGPAPTRLRE AAADPATRREVGWVASHAVLGTALGLVGLTLPLTSATDAAFPLWWSFVPPSEATPSLGL WTVQDWPGAFAVSLLGIGWFALTLAVAPGMARLQAWPGRRLLTPPPGTDLVTRVTELTA TRAAALDAHATELRRIERALHDGTQNRLVAVTVLLGASRRAVSRGSADADALLERAQDA AEQALAELRAVVRGILPPVLADRSLTDALSGLAGSCPVPCRVDADVEGRFAASVEATAY FVVAEALTNVARHSGARAASVTVRHRDGRLWLRVTDDGRGGADEHGGSGLAGIRKRVEA LDGVLTLASPPGGPTTLEAGLPCGS" gene 70924..71127 /locus_tag="EAO74_RS13620" /old_locus_tag="EAO74_13630" CDS 70924..71127 /codon_start=1 /inference="COORDINATES: similar to AA sequence:RefSeq:WP_014154384.1" /locus_tag="EAO74_RS13620" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13630" /product="hypothetical protein" /protein_id="WP_124274404.1" /transl_table=11 /translation="MADSTRRSARPVLWLLLLLCAVCNAVTSMMGGIATAVSVAAGLAA LACGIALVADHRRARSTERNAR" gene 71124..72032 /locus_tag="EAO74_RS13625" /old_locus_tag="EAO74_13635" CDS 71124..72032 /EC_number="3.4.-.-" /GO_component="GO:0016020 - membrane [Evidence IEA]" /GO_function="GO:0070007 - glutamic-type endopeptidase activity [Evidence IEA]" /GO_process="GO:0071586 - CAAX-box protein processing [Evidence IEA]" /codon_start=1 /gene_functions="biosynthetic-additional (rule-based-clusters) Abi" /gene_kind="biosynthetic-additional" /inference="COORDINATES: similar to AA sequence:RefSeq:WP_020134340.1" /locus_tag="EAO74_RS13625" /note="Derived by automated computational analysis using gene prediction method: Protein Homology." /old_locus_tag="EAO74_13635" /product="CPBP family intramembrane glutamic endopeptidase" /protein_id="WP_222723308.1" /sec_met_domain="Abi (E-value: 4.1e-13, bitscore: 46.6, seeds: 823, tool: rule-based-clusters)" /transl_table=11 /translation="MSAATQLGAGSPPAPSTPEPRGGWRAGMRRYPLTWFFSLAFVLSW VGWVPYILSGNGQGVLDFTFPGGEAAGQLLGVLPGAYLGPILSAFIVTAVADGRPGLRA WAGRMTKWRVGWRWWAAIIVTVPLVLVLTLYALGGESPVMPSAVVLVAFLPGLALQMVT TGVAEEPGWRDFAMPRLQDRFGPVRGTLVLGPLWGAWHLPLYLSDWGGPHVLWWTPVEF IATTIAFSFVMTWVFNHTRQALLLAMLLHTSVNNYFSVAFTGMFPSLDPAYAGHAFLVS STAAAAVLLLATRGRLGLPRA" ORIGIN 1 ctggacaagg ccaagaagga gttcaaggcc gagaccaagg agctcaccgc caagagcggc 61 gagaccccgg ccgaccgtga gcagcgcctc gcgtcgctcg ccgagggcgg ctacaacccg 121 gtcatcggcg tcggtttcgc ctaccaggcc gcgctcgaga aggtggccaa ggctcacccc 181 gagaccacct tcggcctgat cgactcggtc tccgaggcga agaacgtgtc ctccatcgtc 241 ttcacggagg agcagggctc ctacctcgcc ggtgtcgcgg cggcgctgaa gtccaaggac 301 ggccaggtcg gcttcatcgg cggtgtcgac ctcccgctga tcaagaagtt cgcggccggc 361 ttccagcagg gcgtcacgga cacgaacccc aaggccaagg tccagatcca gtacctgtcc 421 accggttcgg acctctccgg cttcggcagc ccggacaagg gtgaggccgc cgccaagggc 481 atgctggaca agggtgccga cgtcgtcttc gccgccgcgg gcggctcggg cgccggtgcg 541 atcgaggccg tggccggcaa gaagggcgcc tggtccatcg gcgtcgactc cgaccaggcc 601 aaggacccgg ccctgtcgaa gtacgccgac acgatcatga cctcggtcgt gaagaacgtc 661 gacagcggtg tctacgacct ggtgaagtcc gtcaaggacg gcaagccgct caccggcacg 721 cagacctact ccctggccga ggacggcgtc agcctgacca ccacgggtga ccacctcaag 781 gacatccagt ccaagatcga cgaggcgaag aagaagatcg ccgacggctc gatcaaggtc 841 aagaccacga cctgaccggc ccgctgaagt cggggtccgc aggcgcggtt tccgccgcgc 901 ctgcggaccc cgattcacgt atacctccgg gccggggtcc ctcggcatgt gtcggtatcg 961 tgcccctggt tcgccacctg tcgccgggtg gccaacgatt cggtggcgct acgcgcgtag 1021 tgcccatcga gcgcggtatt tttcgccacc ggtccccgcg ctgtgtccgt acatcgcccg 1081 ccctccgctc ctgccaagga gagtgcgcca tcaaagcgtc cagcagtcct catgccgtag 1141 agctccgcgg catcaccaaa cgattccccg gcgtcgtggc caaccacgac atcgacatca 1201 cggtgagccg tggcaccgtc cacgccctcg tcggtgagaa cggcgccggc aagtccaccc 1261 tgatgaagat cctttacggg atgcagaagc cggacgaggg caccatctcg gtggatggtg 1321 aacaggtctc gttcagcagc ccgggcgacg ccatcgaccg cggtatcggc atggtgcacc 1381 agcacttcat gctcgccgac tacctcacgg tcctggagaa cgtcgtcctc ggctccgaga 1441 agctgcacgg catcggggac agggcgcggg cgaagatcaa ggagatctcc gacgcgtacg 1501 gcctcggcat ccgcccggac gccgtcgtcg aggacctcgg tgtcgccgac cgccagcggg 1561 tggagatcct caaggtcctc taccgcggcg cccgcaccct gatcctcgac gaaccgaccg 1621 cggtcctcgt gccgcaggag gtcgacgcgc tcttcgacaa cctgcgtgag ctgaaggccg 1681 aaggcctcac cgtcatcttc atctcccaca agctgggcga ggtgctgtcg gtcgcggacg 1741 agatcaccgt gatccggcgc ggtacgacgg tgggcaccgc tgaccccgcg accaccacca 1801 gcaagcagct cgccgagctg atggtgggca gcgaactccc ctcgcccgag acccgggagt 1861 cgaccgtaac ggacacgccg atgctggccg tggaggacct gcggctgacg gccaccgacc 1921 ccgacggtgt ggtgcgcgcc gtgctcgacg gcatcacctt caccatccac aagggcgaag 1981 tgctcggcat cgcgggcgtc gagggcaacg gccagtccga actcgtcgac gccatcatgg 2041 gcatgcgcac cctcgacaag ggctcgctca cgctcgacgg cgcggacatc tcccgtacgg 2101 ccacgcgcaa gcgccgcgag gacggcatgg ccgtcatccc cgaggaccgg caccggcacg 2161 gccttctcct ggacgcgccg ctctgggaga accgcatgct gggtcacgtc accgagcggc 2221 ccaacagcaa gggcgccttc ctcgacctca aggccgcgcg cgccgacacc gagcgcatcg 2281 tgcgcgagta cgacgtccgc acgcctggca tcgaggtcac cgccgcctcg ctctccggcg 2341 gcaaccagca gaagctgatc gtcggccgcg agatgagcca caaccccaag ctgctgatcg 2401 ccgcgcaccc cacccggggt gtggacgtcg gcgcacaggc gcagatctgg gaccagatcc 2461 gcgaagcgcg ccacgagggc ctcgcggtcc tgctgatctc cgccgacctc gacgagctca 2521 tcggactctc cgacacgctg cgcgtcatgt accgaggcca gctcgtggcc gacgccgacc 2581 cggcgaccgt cacccccgag gagctcggct ccgcgatgac cggcgccgcc gccggccacc 2641 tggaggcccc cggccccacg gccgccggtg acaccgcggc cgacggctcc gagaccgacc 2701 cccgggacgg gggagaggac cgatgaagaa gttcgacaag gagcggctgc tcctggggat 2761 cgccgccccg ctgctcgcca tcgtggtcgc gttcctggtg accgccctgg tgctcgccgc 2821 caccggcaag gaaccgttca gcgccttcgg catcatgttc gactacggac tgaagtcgga 2881 cagccaggtc tacatcctca acaaggggac gacctactac ctcgcgggtc tcgcggtcgc 2941 cgtcggcttc cgcatgaacc tcttcaacat cggcgtcgac ggccagtacc gcctcgccgc 3001 gttcttcgcc gccgcactcg gtggcgcgct gacgctgccg ggcgccctcc agatcccgct 3061 gatcatcctc accgcgatga tcgtcggagc gatgtgggcc ggtatcgccg gtctcctcaa 3121 ggtcacccgc ggcgtcagcg aggtcgtctc gacgatcatg ctgaactcca tcgcgacggc 3181 catcatcggc tacctcctcc agcagggccg cctgggccac ctcgacaagg ccgggacgaa 3241 ggtctccacc accccgatcc cggagtcctc gcacttcttc gagttcccga ccacgccgac 3301 gcccgtctgg ggcttcatcg tgatcgcggt cgtcgccggc gtcgcctact ggttcacgct 3361 cagccgcacc cggttcggct tcgacctccg cacggtcggg cagtccggct cggccgccga 3421 ggccagcggc gtcgacgtca ggaagatggt cgtcacgtcc atgctgatct ccggcggtat 3481 ggccggcctg atcggcatgc cgacgctgct caacgacagc tacgagtaca gcggcgactt 3541 cccggtcggc atcggcttca ccgggatcgc catcgcactc ctcggccgca accaccccgt 3601 cggcatcgcg ctcggcgcgc tgctctgggg cttcctggag cggggcaccg gcaagctcga 3661 attcgagggc tacgacaagg agatcgtcgg cgtcatccag ggcgtcatcg tcctctgcgt 3721 cgtcatcgcc tacgaagtcg tccgccgcta cggcctcaag cgccagcaga gcaaggtcgg 3781 cgcggaactc gccgccaagg ccgcacgtaa ctccgaccag caggaggtgt cggcgtgagc 3841 gccacggcga cttccacccc gccgcccgcg gcccccaagg tctccggcgg caagggcggc 3901 cgcacccgct tcagcttccc cgtcgtcctg ctgatcatcg cgggcgccct gctcgcgctg 3961 tccgccgtac gcgcgatcac cggcgcccag gacgtcacct cggccgggca gatcagcgcg 4021 gccctcgcga tggccgtgcc gatcgggctc gccggtctcg gcgggctctg gtccgagcgg 4081 gccggcgtgg tcaacatcgg cctcgaaggc atgatgatcc tcggcacctt cttcggtgcc 4141 tgggccggct ggcagaccga cccgtggctc ggcgtcctgg ccggagtcgt gggcggcatg 4201 ctcggcggtc tgctgcacgc cttcgccacc gtcaccttcg gcgtcgacca catcatctcc 4261 ggtatcgcca tcaacatcct ggccctcggg ttcacgacgt acttggccaa gctgtggttc 4321 aacaccggcg acgcggccga gaagggcggc agccccaagc agtcgccacc ggccgacagc 4381 atcacgcagg tcacggtgcc cggtctctcg gactggctgc attcactgga gaagcaccac 4441 tggttcttcg tctcggacct cgcgggcatc ctcggcggac tcgtcaccaa cgtctcgctg 4501 ctgaccctgg tggccgtgct gctcttcgcc ggcacgttct tcgtcctgtg gaagacctcg 4561 ttcggcctgc ggctgcgctc ctgcggcgag aacccggtgg ccgccgagtc cctcggcgtg 4621 aacgtctacc tctacaagta catcgccgtg atcgtctccg gcggtctggc cggcctcggc 4681 ggcgccttcc tctccctggt cacctcgcac atctacaacg agggccagac cggaggccgc 4741 ggatacatcg gtctcgccgc gatgatcttc ggtaactggc ggcccggcgg actcgccatg 4801 ggcgcgggcc tgttcggctt cgccgacgcg ctccagctgc gcaacggcgg cgagtccgtc 4861 cacgcgctgc tcctgctgct cgtggtgatg ctggccgtcc tcgcggtctg gaagctctac 4921 cgcaagcgct tcgtgcccgg tgtcatcagc gcggtcatcg ccgccgcggt gctggtctgg 4981 tacctcgcca ccgacacggt gcccaccgag ttcgtcagcg ccaccccgta cgtcgtcacc 5041 ctgctcgtgc tctcgctctc cgcgcagcgc ctgcggatgc cgaaggcgga cggcatgcgc 5101 tatcgcaagg ggcaggggaa gtgacggacg gcgcggtccc cgtcgactgg gacgcgctgc 5161 gcgcggccgc ccgggacgcc atgtcccggg cgtacgcccc gtactcgggc tacccggtcg 5221 gtgtggcggc cctcgtcgac gacggccgca tgatcaccgg gtgcaacgtc gagaacgcct 5281 cgtacggcat cggcctctgc gccgagtgcg ggctggtctc gcagctcgcc gccacgggcg 5341 gcggccggct gacccacttc acctgcgtgg acggcacggg cgccgtgctc gtcccgtgcg 5401 gccggtgccg gcagctgctg tacgagttcg gggggcccgg cctcgtcctg gagaccccgg 5461 acggcttccg tacgctcgac gagatgctgc cgcaggcctt cgggccccag cacctggggt 5521 agtaccccgc cgccgccgcg tcccccggcg ggccccaccg gcccgccggg gaacgcggcg 5581 gcggaacgtt ccctctctat gcgcgtagag tcaacgggac tctctcgccc accatccggc 5641 cggaaggact cccatcccat ggacgccatc tccgtcatcc gcaccaagcg ggaccgaggc 5701 gagctcagcc ccgagcagat cgactgggtc atcgacgcgt acacccgcgg cgaggtcgcc 5761 gacgagcaga tgtccgcact ggccatggcg atcctgctca acggcatgaa ccgcaccgag 5821 atcgcccgct ggaccgccgc gatgatcgcc tccggcgagc ggatggactt cggcgcgctc 5881 tcccgcccca ccaccgacaa gcactccacc ggaggcgtcg gcgacaagat caccctgccg 5941 ctcgccccgc tggtcgccgc ctgcggcgcc gccgtgcccc agctcagcgg ccggggcctc 6001 ggccacaccg gcggcaccct cgacaagctg gagtccatcc ccggctggcg cgcccacctc 6061 tccaacgccg agatgctgga cgtcctcgac accaccggcg ccgtgatctg cgcggccggc 6121 gacgggctcg cccccgccga caagaagctg tacgcccttc gcgacgtcac cggcaccgtc 6181 gaggcgatcc cgctgatcgc cagctcgatc atgtccaaga agatcgccga gggcaccggg 6241 gcgctcgtcc tggacgtcaa ggtcggctcc ggcgccttca tgaagaccat cgaggacgcc 6301 cgcgaactgg cctccaccat ggtcgcgctg ggcaccgaca gcggcgtacg gacggtggcg 6361 ctgctcaccg acatggcgac ccccctcggt ctgaccgcgg gcaacgccct ggaggtgcgc 6421 gagtccgtcg aggtcctcgc cgggggcggc ccgcaggacg tcatcgacct gaccctggcg 6481 ctcgcccgcg agatgctcga cgccgccgga ctcaaggacg ccgacccgga gaaggccctg 6541 gccgacggct ccgccatgga cgtctggcgc cgcatgatct ccgcccaggg cggcgacccg 6601 gacgccgcgc tccccgtcgc ccgcgagcgg cacgtgatca gcgccccgtc ctcgggcgtg 6661 ctgacccgcc tcgacgcgta cgacatcggc gtcgccgcct ggcgcctcgg cgcgggccgc 6721 gcgcgcaagg aggacccggt gcaggccggc gcgggcgtcg aactgcacgc caagccgggc 6781 gacacggtga ccgagggcca gccgctgctg accctgcaca cggacacccc cgagaagttc 6841 gagtacgcgc tgaaggccct gcccggctcg tacgacatcg cccccgcggg cacgcccttc 6901 accgccacgc cggtggtgcg ggaacgcatc gcctgacctg cggctttccc tctcgggtga 6961 acgggaccgg tggaccacca ccggtcccgt tcaccctgct gatctcgtcg ccctgccgcg 7021 cgcggtcgcg tccgggccga tgagttccgg gcgctccggc ggtctccctg gtgtggatgc 7081 cgtgaccccg aacgccctcg tcctcaccgg ccggatcacc cgcgccgatg tgccgggcct 7141 ctgcgcccgg ctggaggcgc tgctcagcgg cgccccggag gccgccgtcg tggactgcga 7201 cgtcggcggt gtcgtacgcc cggacctcgc cctggtcgag gcggtcgccc ggctggggct 7261 cgtcgcacgc cgggccggtg gcgccgagct gcggctgcgc aacgtcccgg ccgaactcgg 7321 cacgctgctg gacctgatgg ggctggccca ggtcctgggc gtcgtacaag cggctcccga 7381 gtgaaccgcg ctcagcgggc cacggcggtg tcccgggcct cgccgtagtc gcagaggacc 7441 tgcaccacgt atccgtcggc gtagtcgtcc ggcacgtcct tcagcgacgg cgccgccgag 7501 ggcgtcgggc acgaaccctc cggctgcggt cccggggcgg ggttctcgtc ccggaccccg 7561 gcggcggggg aggggcccgg gcccgccgtg gcggacggct cgcccagcca cagcgtcacc 7621 gcccagccac ccgccaccag cagggcccag ccgatcacca ccggacgtct cacactcacg 7681 ccccggcatc cagatggtcg gggagcccga acagcgggaa ccagcgcggg gtgtccagga 7741 agcagtgcat cccggtgatg gcaccgtccg agatgtcgat gacctgcacc gcccacggca 7801 cgaaccccgg cccgtccgga ttcggcttgt agtgcgcgaa ggccggcgtc ccgttggccc 7861 gggtcgccac caggcgggaa ccggcacagc tcgcgccgat gctgagcatg aagcccgtga 7921 tgtcgtcgtg cccctggagc cagaggtcga acggcggcat ggtcatcacg gcgtcctcgt 7981 ggagcagtgc cgtcagcgcc gccatgtcgt acccctcgaa cgccgccaca tagcggtcca 8041 gcagcttgcg ctgctcgtcg tccagcggat tcgcggggtc cggcgcggtg ctgtccgtgt 8101 cggagagggt cgcccgcgcg cgctgcaggg cgctgttgac cgaggcgacc gaggtgtcga 8161 gcagctcggc gacctcgctc gccttccacg ccaggacctc gcggaggatc agcaccgccc 8221 gctgcttggg cggcagatgc tggagcgcgg cgacgaacgc gaggcgcacc gactcccggg 8281 ccacggccgc ctccgccggg tcggccaccg agggcaggat gcgcccgtcc ggcatcggct 8341 ccagccaggt gttctccggg agcgggttca gcgcggcctg ggccagcggg gtcgggccgg 8401 tcagatccac cggcctggcc cgcttgttgc ccgcgttcag catgtcgagg cagacgttcg 8461 tcgcgatgcg gtacagccag gagcgcaggg aggaacggcc ctcgaacttg tcgaagttac 8521 gccaggcacg caccagcgtg tcctggaccg cgtcctccgc ctcgaaggcc gagccgagca 8581 tccggtagca gtaaccggtc agctcgaccc ggtgtccctc cagacggctg tcgatgtcag 8641 ccgtcgctgt ctgatcactc atcgctccac ccctgttgcg ctgtgacacc gctcactcag 8701 cactgtggaa gctaccgcag ggcactgaca accggggcgg gaagcgtgga aaccgctgct 8761 caggtgccgg gcttgcgtcc gtagacgaag acgtcgtcgc cgttcctcaa caggttccag 8821 tatgacttcg cgtccgccgg gcgcatgttg acgcagcccg ccgaacccgg gttgttgtac 8881 atggtcttgg tgaccgagtg gaacgcctgc ccgccgtcga agaactgggc gtacggcatg 8941 cgcacgtcgt agagcgtcga ccagtggtcg atgttgcgcc agtagatctt cgtcgcgccg 9001 gtccgcgtct ccgcgccgtt acggcccgta cgcaccggca ccggcccgaa cctcagcttg 9061 gacccgtcct ggatccagct cagctgcctg gtcaggtcca cacaggcgat gcggcccttg 9121 ttcgtggggc acttcttcgc cttgttcggg gtcttgcccg cggcctgctg ggcggtgatc 9181 gtcttcatcg tgcgccaggt caccggcccc gcgtagccga tggccggggt gatgcccttc 9241 gccacctgga acgagcggat ggccttgcag tcggccgcag actgctttcc gtcggccgtc 9301 cgcttcagcc acttctccac ctgcttctgg tacggcccct tcgccgccgt gcacgacgcc 9361 gcctgggccg ccgtcccggt gcccaggacg agggccggtg caaccaccag gccggcgacg 9421 gacaggacgg ctccgcgccg cacccctgcg ccgcgtatct tccccatgat tcccatgtac 9481 gcctgctccc cttcgcgtcg tccgcggtct gtgactccgc ttgttggacg tgcgcagggg 9541 agctgcggtt gtgccgtgcc aggtctcagt tcggcacagc tgcccggagc cgctccgtcc 9601 gggccgcccg ggtcccgaac agggtgatcg acaggacacc gatgaccgcc aggaccccca 9661 gggcgaccgt gccggcccag cctcccgcgt ggaaggcgac ggcgccgagc gtgccgcccg 9721 cgctggagcc caggtagtac gcggactggt agagcgccga cgcctgggcg cggcccgagg 9781 tcgccgtacg gctcaccgag gacgaggcga ccgcgtgccc ggcgaagaag ccggccgtga 9841 tcaggacgag cccggccagg acggccacca gctggtcggc cagcgagagc agcagacccg 9901 cggccgtcgt ggagacggcc aggtagagcg cgccccggcg gcccagccgg gccaccagcc 9961 ggcccgcggc ggcggaggag accgtgccga cgaggtagac caggaagacc gagccgacga 10021 tgccctgcgg caggccgaag ggctcgtcga cgagccggta gccgatcacc gtgtacaccg 10081 cgccgaacac cgtcatgaac agcgcgccga tcgcgtacag ccggcgcagc agcgggtcgg 10141 agaggtggcc ggtgacggtc ctcgccaggg ccttcgggtt gagcgaggca gggctgaagt 10201 gccgggccct ggggatcatg aggtggaaga ccaccgcaca ggccaccgcg agcagcccga 10261 tcgcgcccag cgccatccgc cagccccaca gctgggccac ccagccggcg aggatgcggc 10321 cgctcatgcc gccgatgctg ttgcccgcca cgaacaggcc gatcgcggcc accagggcct 10381 tgggccgtac ctcctcggcc agatacgcca tcgcggacgc gggcagtccc gccagcgccg 10441 cgccctggac cgcgcgcagc gcgatcagcc agccgatcga cggggcgaag ggcacgagca 10501 gcccgatcac cacggcgacc gccagcgagg ccgtcatcat ctggcggcgc ccgaagcgct 10561 cggagagcgc gctcagcggc aggacgcaga gggccagggc acccgtcgcc gcggagaccg 10621 tccagctcgc ctggccggcc gtcgcgccga aggacgcgga gacggcgggc agcagggcct 10681 gggtggagta gaggagggcg aaggtcgcga tccccgccgc gaagagcgcg aagctcatcc 10741 ggcggtagcc gggaccaccg ggtgcgaggc ggtccgggac ggtcggggag gcggcggcgg 10801 tggatgacgg aacggcggcg tccagcacga cggtggacgc cccggtactg gcaggaggca 10861 tacggcgaac gtagaccgcg gggtttcatg cgtccaatgc atgaaaccct cataatcgtt 10921 cccatggcgc atcaatacag ctcacagcca cggctgtcac cgagcagtta cgaagaagac 10981 atccgggcgg tcctcgcgcc acgcctcgcg tacttcgagg cggtggcccg ccacgagcac 11041 gtcacccggg ccgcgcacga gctcggcgtg ccgcagtcga cgctgtcgcg ggccatggtg 11101 aggcttgaac aggacctggg cgtcgccctg ttcgcccgcc ggggccgcac cgtctcgctc 11161 acccccgccg gccgcacctt cctgggctcc gccgaacgcg ccctggccga ggtggagaag 11221 gccgccgact ccgtacgcgc cgacgccgac cccacggcgg gcaaggtcgc cttcggcttc 11281 ctgcacacca tgggatccga gaccgtgccc ggcctgatcc gcgccttccg cgtggaccac 11341 cccagggtcc gcttccagct cgtccagaac tacggcgagg cgatgatcga acggctgcgg 11401 gcgggcggcc tcgacctctg cctcacctcg cccgtccccg acgccccgga cctcgtcgcc 11461 cgccgcctcg acgagcagcg gctgcgcctg gtcgtccccg acgaccaccg gctggcgggc 11521 cgccggcgca tccgcctcgt ggaggccgcc gacgaaacgt tcgtcaccct ggaacccggc 11581 tacgggctgc ggcggatcac ggacgacctc tgcgcggagg cgggcttcac cccgaggatc 11641 gcgttcgagg gcgaggaggc cgagacgctg cgcggcctgg tcgccgcagg gctcggggtg 11701 gcgctgctgc cgccgcccgc cgtcgcccgg cccggtgtgg tcgagctgac ggtcaccgcg 11761 ccgcgcgccg cccgcgagat cggggtcgcc tggctggacg gccaccccga caccccgccg 11821 gtggccgcct tcaagcgctt cctgctgtca cgccggggaa gcctgctgcc cgactgacct 11881 ccgggtacgg tgctcagcgc cgcagcgacc gtccgaagcc cgccgcgagc ggcatccgca 11941 gccccagcgg cggcggagcc gcgaacgcgt cggccaccgg gcgcgcgtag gagcgggcga 12001 acagcgagcc ccgtacgaag tccgaggcca gcgccaccac ttcggaccgg tgctggcgca 12061 gggcgtgccc gtccgagtgg acctcgaagc ggcaggtgtc ccggttggac ttcttggccc 12121 gctcggccag ccggtaggag agctccggat cggtccgggc gtcgttcgtg ccgtgcacga 12181 tcaggacccg gcgccccgcc aggtgcttca ccggctccgg ttccggctcc gtgccctcgg 12241 ggagccaggg ggccatcgcc aggacggagg tgacggcggc gtgcccggcg ccgcgcaggg 12301 cggcccggcc gcccatgccg tgcccgacca ggcacaccgg gatgtccccg tagcggcgta 12361 ctacctcgtc ggccgcccag tgggcgtcgg ccgccggatc cgcgcccgag ttccagcccc 12421 gggaccggta ccgcacgacg tgcaccgcga gcccgtcgtc ctggccggcg cgggccaggg 12481 cccgggcgaa cggcagctgc gccgcgtacg aaagggtgga gggacggcgc cgcgagtcgg 12541 tctcgccgtc cgggagcagc aggacgacgc cgctgacctc gggtgccgct ccggccgtga 12601 gaacggcccg tcccagcctg gcggcaggca ggggaagtgc gcgctgtgcc atcagtacct 12661 agccagggga cgccccgctt cagcggggta ggaagtgact tctgagccct gctctgacct 12721 caactgggag cacggatgtg cactgttcac ctgagccagc ctctctaccg cactagacat 12781 gcggcacttg tatagtgatc gtgtgactac ggccaggaag gttcgccgat tttccggcgg 12841 tgtgtgcgac ctcgggctac acgtggtctg gtgcccgaag taccgccgtc cggtcctcag 12901 cgggcgggtc gcggaacggt tggacgagtt gatccggacg aaggcggacg aacgcggttg 12961 ggaggtcaac gcccttgagg tgatgcccga ccatgtgcac ctgttcgtga agcatgaccc 13021 gaagtcgtcg gcctcgtacg tggcgaacca gttcaagggc ttcacgtctc gcgtgctgcg 13081 cgaggagttt ccacacctga agtcacggat gcccaccctg tggtcgtcgt cgtacttcgc 13141 cgcctcggtc ggcgccgtgt cggcggccac ggtcgagaag tacatcgaca cccagtggga 13201 acgcccgtgg aagaaggggg acggctcgtg atccgcgcat acaagttcct cctgcgcccc 13261 acggcccgtc aggtgacagc gctcggtgag atgctgcggg accactgctc cctgtacaac 13321 ggcgccttgc aggagcgtcg ggacgcctac cggcacagct cgaagtcgag catcaagtac 13381 ggcaaccagt ccgcccagct caaagacatc cgcgcattcg acccggaccg gcagggtcgc 13441 tggtcgttct cctcgcagca ggccaccctg cgccgcctcg acaaggcgtt ccaggcgttc 13501 ttccggcggg ccaagtccgg gcagaccccg ggctaccccc gtttcaaggg cgcagggcac 13561 ttcgacaccg tcaccttccc cagggacggc gacggctgtc gttgggactc caccccacac 13621 gatgcgcaga cccgcgtacg gctccagggc gttggtcacg tccgtgtgca catgcaccgg 13681 cccgtacagg gtcgcgtcaa gacgatcagc gtgaagcgcg aagggagccg ttggtacgtc 13741 gtcctcgcat gcgacgacgt gcccgccgag gaaatgcctc ccaccggggg aaacgtcggt 13801 atcgacttgg gcatcgccca cttcctcacc acctcggagg gtgaacacgt agccaacccg 13861 cgcttcctcc aggcgatggc cgacgaactc gccgaggcgc agaggaacct tgcgaggttc 13921 ccgaagcggg cccggcagcg caccaaacgc caccgcgcgg cggcccggaa ggtcgccaag 13981 ctgcactgca aaatccggcg gcagcgtgct gatttccatc acaagaccgc gcgtacgctg 14041 atcaccgact acgacgtgat cgcgcacgag cgactgaaca cagtgggcat gaccaagagc 14101 cccgcgccca agaccgcccc caggcagccc ggcagcttcc tgccgaacgg ttctgccgcg 14161 aaggctggcc tcaaccgcag catcttcgac gcgggttggg cgcagttcct cggaatcctg 14221 gcgaacaagg ctgagagtgc cggtcgcctc acggttccgg tggacgcgcg caacacctcc 14281 cgcacgtgcc ccgagtgcgg gcacgtagcg aaggagaacc gcgtcaccca ggaaaggttc 14341 cagtgcacgg cgtgcggctt cgcggcgaat gcagaccatg tcggcgcgac gaacgtcctc 14401 aacagggccg ggctggtcct ctgcgcagag gcttagccac cgacgcagga agcccgcgcg 14461 tttacgcgaa ggtggagtca cgacagaaca gtgtcagaag gccaggtgta ttccacccgg 14521 cttcgcggtc actgttacgc atcggcgacc agcgctctac gcgcgtaggc gctagagtgc 14581 cccaatgacg agccagaccc tgaacgtccc cggtcccgac cagatccgcc gtgcgcccaa 14641 ggtgctcctc cacgaccatc tcgacggcgg gctgcgcccc ggcaccatcg tcgacctggc 14701 gctggagcag ggctacgagg cccttcccga gacggagccc gacaagctcg gcgtgtggtt 14761 ccgcgaggcg gcggactccg gttcgctgga acgctacctg gagacgttcg cccacacctg 14821 cgccgtcatg cagacccgtg acgcgctgtt cagggtggcc atggagtgcg ccgaggacct 14881 cgccgaggac ggtgtcgtct acgccgaggt gcggtacgcg cccgagcagc acctcaccgc 14941 cggcctgacc ctcgaagagg tcgtcgaggc ggtcaacgag ggcttccgcg agggcgagcg 15001 ccgggcccgc gccgccggcc accgcatccg ggtcggcgcc ctgctcaccg cgatgcggca 15061 cgccgcccgc gcgctggaga tcgccgaact cgccaaccgc taccgcgacc tcggtgtcgt 15121 cggcttcgac atcgcgggcg cggaggcggg ctacccgccc acccgccatc tggacgcctt 15181 cgagtacctc aagcgggaga acaaccactt caccatccac gcgggtgagg ccttcggcct 15241 gccgtcgatc tggcaggcgc tccagtggtg cggcgcggac aggctcggcc acggtgtccg 15301 catcatcgac gacatcgaga tcgccgacga cggcagtgtg acgctggggc gcctcgcctc 15361 ctacgtacgc gacaagcgga tcccgctgga gctctgcccg acctccaacc tccagaccgg 15421 cgccgcggcc tcgtacgcgg aacaccccat cgggctgctg aggaagctgc atttccgcgc 15481 gaccgtgaat acggacaacc ggctgatgag cgggacgagc atgagccgtg aattcgagcg 15541 actggtcgac acattcggat acacgctcga cgacatgcag tggttcacag tcaatgcgat 15601 gaaatcagcg ttcattcctt tcgatgaacg tctggcgatg atcaacgacg tcgtgaagcc 15661 cggttacgcg gagctgaagt ctgaatggct cttccgtcag acggctgtga ccagcgcttc 15721 ctcgtccgtc gcgggctgag cgggcgaaaa gcgtaacggc cgggagcgcc ttgttcccgc 15781 ccgttttccg tgtcccggca tgtttgcggg aggggtgcgc ggatgactac gttgcagagc 15841 cgctcacatc cccttcccca aggatgaatt tcacatgaag cagtctgccg tcaggaccct 15901 cggtgtcgcc gctctcggtg ccgctttcgc cgccgccggc gcgggcagtg cctccgccgt 15961 cgccgtgccc gtcgacgccg ccgcggccgc cctgcccgcc ggtgtcgcgc tcgactccgt 16021 caccgacgcg ctgcccgccg tgcagaaggc ggccggcggt ctcctcgacc agcagcagcg 16081 cggcagcagc gatctctcgg cccccggcac caacctgctc ggcgggctgc ccgccggcgg 16141 tctcacgggc gtcctgccgc tcggcaactg accaccgcac gcacatgtgg ggcgcacacc 16201 cggnccgggt gtgcgcccca caggtctctc tccccgtggt ccgtgcggtc accaggccgt 16261 cgcggccggg ctcttctccg acggcagcag gatccacagc gccaggtaga gcaggaactg 16321 cgggccgggg agcagacagg agaccagaaa gatcacacgc atcgtcccgg cggaggtgcc 16381 gaagcgccgt gccagcgctg cgcacactcc accgatcatg cgtccgtcac gggggcgggc 16441 aagtgcggcc atggtgggct ccttcgcgaa ccggttcggg gagcagctcc gtcgtgctcc 16501 ccctacctcc atagtggctc cgagaagggg gacaaagcat cgctctacgg tgcgataccg 16561 accctggtaa tcgtcggggt cgacccctga gggccctccg cgcgcaccga ccgggccccg 16621 atccgggaca ggtcaccggc ccccgcgcgg tttccccggc gcagccgtga ccgcgacagc 16681 gggacgatca gcagatgtgc cagcgcgact ccggacgtgt tcagcagcag cgagtcgacg 16741 tcgacgacct ggccgggcac ccccgtctgc gccagctcga tggccatgga gatcagggcg 16801 cccgccgcga ccgtacgggc cagcgaggcc cacggggaga ccagcagcct gcccccggcc 16861 atcggcagca gtatgcccag cggagccagc agcagcagac cctcaccgat gcggcgtacc 16921 gcctcggcgg ggcccagggc caggtccgcc ctgatcccgg cgaacggctg gaagttcgcg 16981 gccgtcaccc agggcacgtc cagcgggcgc agcgtcagcc agcagacgaa cagaagatgc 17041 gcgaggagga ggaatacccc cgccgcgcgg aagcggatga cggccgggcc gtccgaactg 17101 tgacgcacgt gcaccaagac gccacgaccg gcaggatcgg ttccgccccg ctccgggaag 17161 cctctgtgac gagcggcacg gccgccgggc cgtgtcccgg cggcgcggag ggaagccccg 17221 ggaagctcag gacaggccga cggcacccag cgtgggtacc tcacccggca ggctcttcgt 17281 ctccgacgtg cacaggtacc cgcgcggggc gtagttgccc ggcccgccca gcagcaccga 17341 acccccggag cccagcgact cgctgtccgc gtacgtgcac accacctgcg ccagcgcctc 17401 cgccggcagg tcgtccggct gctcgctgag acgcagcgtg ccctccgggt cccccttgtg 17461 ggcgccggtg acccgcagcc ccgccgggac gtcggtggag aaaccggcgc gccgctcggc 17521 ggcctccggg tcgcgctgca gttcaccgag gagctcctgc gcgatcatga gcggcccgga 17581 ccgcgactcg tcgaactcga ccgtgcgctc caccgtcacc agctgcgacg cgcagaccag 17641 atagaccggt acggagacac tccccgccgg cggagcggag gcctccgcgg acgccgtgcg 17701 gcacggcatc cgggacgggg ccgccccggc gtcgaccggc accgacgtgc tgcggatgcc 17761 gcagcccccg gccagcgccg cacaggccac gacggcggcc agcgcggcga cggcccggcc 17821 gggccgtcgc aggacctcgc gcggtgcgcc gtaggaccgc tcgctgcgcc tcacgtggcg 17881 tcacccttct cgttcccgtc cgggtcgtcg tccggtccct gcgtgccggt cagccgctcc 17941 gcgtcacgcg ggagccgcag cacgaagacc gcgccctcgc cgtccggcag gttcgaggcc 18001 gtgatgtcac cgccgtggat gtgcgcgttc tccaccgcga tggagaggcc gagcccgctg 18061 ccgtcggagc gcgggcggga ggcgctcgcc ttgtagaagc ggtcgaacac gtggggcagg 18121 acctcttggg ggataccggg gccgtggtca cgtacctcga tgaccaggtc gtcctcgtcg 18181 gtccgtacgg acacccgcac cggggacccg ccgtgcttga gcgcgttgcc gatcaggttc 18241 gccaggatca cgtcgaggcg acgcgggtcg agccgcacca tgatgccgcg ctccgcgtcc 18301 agatcgaccg cgtccagcca ggcacgggcg tcgatgcagg cggtcacctg gtcggcgacg 18361 tcgacggtgt ccaggacgag gcgggccgta ccggcgtcga agcgggtgac ctccatgagg 18421 ttctcgacca ggtcgttcag ccgccgggtc tcgctcacca ccagatgcac ggccggggcg 18481 atcatcgggt ccaggctgtc cgcctcgtcc tccagcacct cggcgaccgc cgtgatcgcg 18541 gtcagcgggg tgcgcagctc gtgcgacatg tcggcgacga acctgcggct cgactcctcc 18601 cgggcgctca tgtccgcgac cttcttctcc agggagctcg cggccttgtt gaacgtatgg 18661 gagagatcgg cgagttcatc ggtgccggag accacgagac gggtgtcgag cttgccctcg 18721 ccgagtttgc gggccgcgtc gccgagccgc tggaccggcc gcagcaccgt cgtcgccgcc 18781 gcctgggcga ggagcgccga gccgacgagg gccagcgcgg tggcgatgcc cagggaccag 18841 gccagcgagt tgaggtcctc gcgctcctgg tcgagcgact tcagcatgta cccggcgggc 18901 ccaccaccga tgatcttcgt cccggccacc aggtacgggg tgccgcccac ggtcgtacgc 18961 tgccagaaca ggtggtactc aaaggtgttg gccgacgtca gcggctgctt cttgttcacc 19021 tgcctctgga gcgaggccgg tacgtcggcc ttggtgaagg agtcgaggtc ggaggagccg 19081 gtgacgggct tgccctcgcg ggtgccgatc agcagtacgt ggtagccggg gccgctgctg 19141 gccatctgct cggcggcgtc ccgcaggtcg accgccgtgg gctgcagcgg cagcgaggcc 19201 gcctgggtct gcatctggcg gcggaagtcc cccagggccg tgtcctgcgt acgcgtcagg 19261 accgcctcgc ggttgagcca gtacgcgatg cccgaagcgg acaccgccgc tgtcagggcc 19321 accagcgcga acacgatcag gagccgcagc cgcaggctgg tccagcgaag acccgcgagt 19381 atggaacgct tcgcggtatc gctcactgag gcgagtccag ccggtagccc acgccccgca 19441 cggtacggat cagggtcggc gaggacggca cgtcctccac cttcgcccgc agccgctgca 19501 cacacgcgtc caccagacgc gagtcaccga ggtagtcgtg ctcccacacc aggcgcagca 19561 actgctgccg ggacagggcc tgtccgggcc ggcggctcag ctccagcagg agccgcagct 19621 cggtcggcgt gagctgcagg tcctccccgt tcttcgtgac ggtcatcgcc gaacggtcga 19681 tgacgacact tccgaacgtc gccgagtccg tggactccct ctccccgcgg cgcaggaccg 19741 cacggatacg ggcgtcgagc acccggccct gcacgggttt caccacatag tcgtccgcgc 19801 cggactccag tcccaccacg acgtcgatgt cgtcgctgcg cgcggtcagc agaatgatcg 19861 gcagttggtc ggtccgccgg atacgccggc acacctcgaa accgtcgatc ccgggcagca 19921 tcacgtccag caccaccagg tccggccgct gctccctgag cagctcaagg ccgtcctctc 19981 ccgtcgccgc ggtggccaca cggtggccct ggcgtgacag cgagagttcc agggctgtgc 20041 ggatggcgtc gtcgtcctcg atcagcaaca ggaaaggcac aggggccatt ctggcccatg 20101 gtggtgccac ctttcgacag tccccccgac ttgatccgcc gacctgggcc ccgacatgcc 20161 ctgtgacagc cctgtgacag tcgggggaca gcgccatgaa actgccccgg caagctcatt 20221 ggcagacgga acgaacggac tccaccgatg gggggcgcca gatgaacgca ctgcacagca 20281 ccacctcaag cgcagttgtc acgcgccttc acgacgtcgg gcggagcccg gagaagtccg 20341 gcgtcggggg acgggggcgt gcacgcggcg ccgggcgtca gcactcgtcg tacctgacga 20401 tggttgacgc ggccacgggg gaaaacgggg gaaccgcgta cggggagggc tcgggggagc 20461 ggaagcccct ggaccggccg gaggatgccg aagcggcgtt caccgcctac gtccaggagc 20521 gccgtgcctc cctgtacgca accgcctacc acctgaccgg agaccggttc gaggccgagg 20581 acctgctgca gagcgccctc ttctcgacgt accgggcgtg ggacaggatc agtgacaagg 20641 cggccgtcgg cggttacctc cgccgcacca tgaccaacct gcacatcagc gcgtggcgca 20701 ggcgcaagct gaacgaatac ccgaccgagg agctgccgga gacggtgggc gacacggacg 20761 cgatgcgcgg cacggagctg cgggcggtgc tctggcaggc gctcgcgcgg ctgccggagc 20821 tccagcgcac gatgctggtc ctgcgctact acgagggccg cacggacccg gagatcgcgt 20881 cgatcctcga catcagtgtc ggcacggtga agtcgagcat ctggcggtcc ctccgccggc 20941 tgcgcgagga cgaggtcctc agcttcggcc gtgacgagga ggagtccttc ggcgagctgg 21001 tggcctgagg tctacggggg gacacgggga aaacggggac acggggaaaa cggnnnnnnn 21061 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 21121 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnngtacggg ggagagcgca gcgggggcgg 21181 acaggccggg gggtcctgtc cgcccccgcc gcgtttcccc ggtgcgctgt cacccggccg 21241 gtgccgcccc ggcgcgtcac ccggccggtg tcgtcccgcc ggggcgtccg ggcccgctcc 21301 cgggggtcag ttcggtaccc ggctccgcgg ggtccggcag cgtcccgccg cggcgtcggc 21361 cagccggccc agggcctcct gcttggcgca ggggtacgcg cccagcgccg cctggcgggc 21421 cacgatgcgg cgttcggcgc gcatcaggcg ccacccccgg cgcagcagga acgggaccga 21481 cttgcggccc tcgcgcagat cccgcaccag ccggcggcgg aacgtcgtcg acggccggcc 21541 gcgcaggcac agcgcgtcgg cgagcagacc cagttcccgg cagcgctcca cgatgtccgc 21601 cgcgaagatg ccctccgcga cgaagagcgg cgtgcgctcg atgtcgagcg tctcgcggcc 21661 cgtccgcgag ctcgtggcga tgtcgtacag gggaacggac gtacgccccg tgcggcacag 21721 ctccgctatg gccgcgaccg cgccgtccgc gtcccaggag agggccgagt cccagtcgat 21781 gtcggcgctg ccggtgaccc gcggcagtgt cggatcgttg aactccttgt agaagtcgtc 21841 caggcgtagc accgggagac cgctgcgggc cgcgagggac gacttgccgg agccggacgg 21901 accggcgagc agcacgacgc gcgtggggat cggttgggaa ctcacagaac agaagtgtga 21961 ggcattgacc cgcgtagggg atccccggga ggtcctgttg gtatcgagca tcacacctca 22021 actactctgc gcgcacggat gattacccga cacgtcccga tcaggtggga aaacatggca 22081 cgtcatgcac tgtccaagcc ccggaaacgc accctgctgc gcgccggtct gaccctcacc 22141 gcgctgggcg cggcgctcgg cgcgggaggc gcggcggccc aggcggcacc gctgcccgcc 22201 ccgcccgcga ccggctcgga caccgccgac agcacgctgg gggccgtcaa cgaggcggcg 22261 gagcccgcgc tgaacagcgt gctgggttac gggatcgtgg gggccgtcaa gcccatcacc 22321 gacctgcagc tcgacccgct ggccgggacc ggggtcgacc ccctggacaa cgcggtgggg 22381 acccagatcg ccgacttcaa gcccgtcacc acggcactgg tcaccgaccc gctgaccagt 22441 ggtgccgcgc tcggtgacct gcccgtggtc ggcgaggtga ccggtctgat caccggctga 22501 tccgacggga catgggtgtg gggccgcccg gaggcggccc cacacccgtg cgagaggtca 22561 gtacgaggag cccgatgccc cgagggcgcc cgtggggtgc cagaccgtct tcgtctccag 22621 gaaggccgtc aaccggtgcg tgccggggtc ggccgaccag tcctcgccgn ccacagcctg 22681 tggatgagcg gcgctgtgcg cctccttctc ggggcggtgg tgggagacgg gtgggcggcg 22741 cacgcgcttc aggttgtcgg ccgccgcgat ctccagctcc ttggccagct ccgcgtcggc 22801 gcccgtgagg tcgatgccgt tcacgtcctg gtgggaggcg agcggcgcgg cgatctccgc 22861 cgtcttcccc gacaggatgt tgacgactcc gcccggcagg tccgaggtcg ccaggacctc 22921 gcccagcgag agcgcgggca gcggggcgtc cgccgaggcg atgacgaccg cggtgttgcc 22981 ggtcgcgatc accggggcca ccaccgacac caggcccagg aacgacgact cctgcggcgc 23041 cagcaccgcg accacaccgg tcggttccgg ggtggagagg ttgaagaacg ggccggcgac 23101 cgggttcgcc ccgcccacga cctggccgat cttgtccgtc cagcccgcat accagaccca 23161 gcggtcgacc gccgcgtcga cgacggccgc cgccttggac ttcgacagcc cctcggcgtc 23221 cgccacctcc cgtacgaact gctcccggcg gccctccagc atctccgcga cgcggtagag 23281 gatctgcccg cggttgtacg cggtggcgcc cgaccagccg ccgaacgcct tgcgcgcggc 23341 cacgaccgcg tcacgcgcgt ccttgcggga ggactgcggg gcgttcgcca gccacctgcc 23401 cttggagtcg ctcacctcgt acacccggcc gctctcggag cgggggaact tgcccccgac 23461 gtacagcttg taggtcttga agacgctcag tcgcccgtca gacatcgagg taggcctcca 23521 gaccgtgacg gccgccctcg cggccgaagc ccgactcctt gtatccgccg aacggcgagg 23581 tcgggtcgaa cttgttgaac gtgttggccc agatgacacc ggcccggagc ttgttcgcca 23641 ccgcgaggat gcgggagccc ttctccgtcc agatgcccgc cgagaggccg tactggctgt 23701 tgttggcctt cgcgacggcc tcgtccggcg tacggaaggt cagcaccgac agcaccgggc 23761 cgaagatctc gtcgcgggcg acggtgtgcg cctgggtgac cccggtgaag agggtcggcg 23821 cgaaccagta gccggacgac ggcagttcgc acggagcgga ccaccgctcg gcgccctccg 23881 cctcaccggt ctcgacgagc gcgctgatcc gggcgagctg ctcggcggag ttgatcgcgc 23941 cgatgtcggt gttcttgtcc agcgggtcgc cgaggcgcag cgtggacagc cggcgcttga 24001 gggcgtgcag cacctcgtcg tgcacggact cctgtacgag gagccgggag cccgcgcagc 24061 agacctggcc ctggttgaag aagatgcccg tgacgatgcc ctcgacggcc tggtcgaccg 24121 gggcgtcgtc gaagacgatg ttggcgccct tgccgcccag ttcgagcgtg gccttcttgt 24181 ccgtaccggc gatctgccgg gcgatggcct tgccgacggc ggtcgagccg gtgaaggcga 24241 ccttgttcac gtcggggtgc tcgacgagcg cggagcccgc gtcgccgtag ccggtcagga 24301 tgttgacgac gcccttgggc aggcccgcct ggcggcagat gtccgcgaag aacagcgcgg 24361 agagcggagt cgtctccgcc ggcttcagca ccaccgtgtt gccggtggcg agcgccgggg 24421 cgatcttcca ggccagcatc aggagcggga agttccacgg gatgatctgg ccggccacac 24481 ccagcgggcg cgggttcgcc ccgtagcccg cgtggtccag cttgtcggcc cagcccgcgt 24541 agtagaagaa gtgcgcggcg accagcggga ggtccgcgtc gcgggtctcc ttgatcggct 24601 tgccgttgtc cagcgtctcc aggacggcca gctcgcggct gcgctcctgg atgatccggg 24661 cgatgcggaa caggtacttg gcgcgctcgg agccgggcag cgccgaccac ttctcgaacg 24721 ccctgcgggc cgccttcacc gcccggtcca cgtcctcggc gcctgcctgc gcgacctcgg 24781 agagcacctc ctcggtggac gggctgacgg tcttgaagac cttgccctcg gcggcctcgg 24841 tgaactcacc gtcgatgaac aggccgtacg agggagcgat gtcgacgacg gagcgggact 24901 ccggagccgg tgcgtagtcg aatgcggatg ccatggcgta tcagtccacc gtcacgtaat 24961 cggggccgga gtaacggccg gtgctgagct tctggcgctg catcagcagg tcgttcagca 25021 ggctggaggc gccgaagcgg aaccagtggt tgtccagcca gtcctcgccc gccgtctcgt 25081 tcaccaggac gaggaacttg atcgcgtcct tggtggtgcg gatgccgccc gcgggcttca 25141 cgccgatctg gacgcccgtc tgctcgcgga agtcgcgtac ggcctccagc atcagcagcg 25201 tgttcgcggg agtggcgttc gtgccgacct tgccggtcga cgtcttgatg aagtccgccc 25261 cggccagcat cccgagccag gaggcccgcc ggatgttgtc gtacgtggac agctcaccgg 25321 tctcgaagat gaccttcagc cgcgcggagc cgcactcggc cttcacggcg acgatctcct 25381 cgtacacctt gaggtagcgg cccgagagga aggcgccgcg gtcgatcacc atgtcgatct 25441 cgtcggcccc ggccgccacc gcgtcgcgta cgtccgcgag cttgacgtcc agcgcggcgc 25501 gtccggcggg gaaggccgtc gccacggacg ccaccttcac cccggagccg gtcagcgcgg 25561 cgacggcggt ggccgccatg tcgggataga cgcagacggc cgcggtgcgc ggggtggtgc 25621 ggtcggtggg gtcggggttc accgccttgg cggcgagggc ccggaccttg cccggggtgt 25681 ccgcgccttc cagcgtcgtc aggtcgatca tcgagatggc gagatcgatc gcgtacgcct 25741 tggcggtcgt cttgatcgaa cgggtgccga gggaggccgc gcgtgcttcg aggccgaccg 25801 tgtcgacgcc gggcagcccg tgcaggaagc ggcgcagcgc actgtcggac gccgtcgcgt 25861 cggcgaatgc aggagcagtg gtgggcatgg tcaccacatg agcatatcta cgcgcgtagc 25921 gacctgtaca gggggcttcc cttctccgtg gcctccacgg accctgccgg gcctctccgc 25981 gacccgcgcg gaccgtcagg cagaatcggg accatgacga gccccacacc ccccgccgag 26041 cccgcccacg ccgaccggac ctaccggtcg ggcgccgggc tggtgagcgg cgcgctgctg 26101 atcctgctgg tcggctggat cggcggcgac gcggtggtcc agggcaaggg atgggtgccg 26161 tggctggcgc tggccgcgct gctgatggtg atcccgctga tcgtggcctt cacgctgcgg 26221 ccggccgtgt tcgccgacaa ggagcggctc cggatccgca acccgttccg aacggtcgtg 26281 ctgccctgga cggacgtctc caccgtgcgt gccgcgtact ccagcgaggt cttcacccac 26341 agcggcgaga agtaccagct gtgggcggtc ccggtctcgc tgcgcgagcg caagcgggcg 26401 gccaggaagg ccggccagca ggcccacgac gacccgtacg gccggacctc cgtccacgcc 26461 gacgtccgcg actcccaggc ccgcgcggcg gccgccgacc gcacggtcga ggacctgcgg 26521 gagctcgccg agggagccac cgcccgcaag gaaccgtcca cggtcaccgc gtcggtccgc 26581 tgggcctacg aggtgatcgc cccggccgcc gtcggcgcgg tgctgctcgt ggtgctgctg 26641 gcgatcggct gaccacggcc gggtccccgc gatacggacg cgcggtgcgg ccggccctgc 26701 cggggacggc cgcaccgcac agtcgcggcg atcgtcggat cagctgtcgt tgttgatcca 26761 cgtggtcgtc tggcactcgt cgtcgccgaa gctggcgacg caggcggaga cctggatgcg 26821 actgcccttg cccccatagg cgttggtgct gctggactcg tagaagtcct tgttgcacga 26881 ggcgttgtcg cccgagctgc cggggttcga acactttccg gtccggtatg tcttccacgt 26941 gccgctgggc tgcttcagct ggttggtcca gttcgtgtag acgctgtaac cgtcggccga 27001 ggtgtccttg gtccagatga gatcgccgta ccgctggaag caggccttcg ctcccttgat 27061 ggtggcgatg cacgtggagg tgctccccgg agaaccgccg acgacgccgg tgttgttctc 27121 cgcggcagcc gcgggattgc tcatcgtgaa gaagagcgct cctccggcca tgagcgtcac 27181 ggcggtcgat ctcaggacag tgcgcacagt gaatcctccc cgttggtctt cctggcattc 27241 cgatccccca agtcctcggt cgaagtggga tcctggggga ttccctggtc aactgatgtg 27301 acgcgaaagc ggcgcacgag gttcacagga accgggagat caatgctgtc ccagggcggg 27361 gccggcccgc cggtcctcag atgccggcgg ccgccgccag gtcccgcttg atggcggcca 27421 gcagttccgc gcccttcgcg tgggcctcgg ggagtccgtc cctggcgggg accgggacga 27481 cgacctccag gtagcacttg agcttgggct cggtgccgct cgggcggacg atcaccctgg 27541 ccccggtgag ctggtagcgc aggccgtcgg tgggcgggag tgcgtccgtg ccctgcgaga 27601 ggtcctccgc cgaggtgacc gggaggccgg ccagggcggt cgggggagtc tcgcgcaggc 27661 gccgcatggc gttcgcgatg accgtcaggt cctcgacccg gaccgacagc tggtccgtgg 27721 cgtgcaggcc gtgttcgagc gccaggtcgt cgagcaggtc gaggagggtg cggccctgct 27781 ccttgagcac ggaggccagt tcggtgatca gcagggcggc cgtgatgccg tccttgtcgc 27841 gcaccccctc cgggtccacg cagtagccca gcgcctcctc gtagccgtag cgcaggccct 27901 cgacgcgggc gatccacttg aagcccgtca gcgtctcctc gtagccgagg cccgccttct 27961 cggcgatccg gccgaggagc gaggaggaga cgatcgactc cgcgagcacg ccggtcacgc 28021 cacggtccac cagatgggcg gcgagcagcg cgcccacctc gtcgccgcgc agcatccgcc 28081 agccgccctc ggccgacggg tcgggcacgg cgacggcgca gcggtcggcg tccgggtcgt 28141 tggcgatgac gatgtccgga tccgcacggc gcgcggtcgc gaaggcgaga tccatggcgc 28201 cgggctcctc cgggttgggg aaggccacgg tggggaacgc cgggtccggg tcggcctgtt 28261 cggcgacgag tacgggcgcg gggaagccgg cccgcgcgaa ggcggccgtc aggaccgagg 28321 tgccgacgcc gtgcatggcc gtgtggacgg tgcgcgcggt gcggggcgat ccgggactca 28381 ggaccgcgtc cgtacgggcg aggtaggcgg ccaggacctc gtcgccgagg acctcccagc 28441 ccccctccgg gcgcggtacg ccgtcgaggg gacccacggc cgcgatggcg gcggcgatct 28501 ccacgtcggc cgggggcacg atctgcgaac cgtcgccgag gtagaccttg tagccgttgt 28561 cgcgcggcgg gttgtggctc gccgtgacct ccacccccgc gacggctccc agatgccgta 28621 cggcgtacgc gaggacgggg gtcggcaggg ggcgggggag cacggccgcg cggaggccgg 28681 ccccggtcat cacggcggcg gtgtcgcggg cgaagtcggc ggacttgtag cgggcgtcgt 28741 agccgatgac gacgagcccg cctccctctc cctgcgcctt caggtaggcg gccagcccgg 28801 cggcggcacg gatgacgacg gagcggttca tgcgcatcgg gccggcgccg atctcgccgc 28861 gcaggccggc cgtgccgaac tggagcgtgc cggcgaagcg gtcggcgagc gcggggaggt 28921 caccggcgtc gatgagcccg gcgagctccg cgcgggtctc ggggtccggg tcctcggcga 28981 gccaggtcct ggcctgcgtg atgaggtcct gctgcacggg gtccgccttt ctgcggtacg 29041 ggggactggg atggagccgc tgcgcggggc tgccgggggc tctgcccccg ggcccccgcg 29101 cctcaaacgc cggcggggct gattccgggc gcccagtgcc tcggaggagg cggggctgtc 29161 agatccggtc caggacgcgg gccagcagtg cgcccatccg ggtcgccgag tcgcggccgg 29221 cctggaggac ctcctcgtgg ttgaggggtt cgccgctcag gcccgcggcg aggttggtga 29281 ccagggagat gcccagcacc tccgcgcccg cctcccgtgc cgcgatggcc tccaggaccg 29341 tggacatgcc gaccaggtcg ccgcccatga cccggaccat gccgatctcg gcgggagtct 29401 cgtagtgcgg gccggggaac tgcacgtaca cgccctcttc gagcgtgccg tcgatctcct 29461 tgcacagggc gcgcagccgc ggcgagtaca ggtcggtcag gtcgacgaag ttcgcgccca 29521 cgatcggcga ggccgccgtg aggttgatgt ggtcgctgat gaggaccggc tggccggggc 29581 gcatgccctc gcgcaggccg ccgcagccgt tcgtcaggat gaccgtcccg cagcccgccg 29641 cgaccgccgt acggaccccg tgcgccaccg ccgcgacccc gcggccctcg tagtagtgcg 29701 tacggcccag gaagaccagg gcgcgcttct cgccgatccg gtacgagcgg atcgtgccgc 29761 cgtggccctc gacggccggg gccgggaaac cgggcagcgc ggtgaccggg aactcggcct 29821 ccgggatgcc gagcgcatcg ccggcggggg cccacccgga gcccatcacg agagcgacgt 29881 cgtgggtatc ggcaccggtc agctcgcgca ggcgggcggc ggcgtcggca gcggcggcgt 29941 gggggtcgcc ctggatgtgg tccggaataa cagatgcgtt cacgcggatg agggtaaccg 30001 ctgattccct acgcgcgtag atgtgtccgg tgagagtctg gccggtcacg ttcgtacgtt 30061 cgtacggaac gggtacggaa ggggcccgga gggcgccgct cagcaggggc gtttgcggag 30121 gttcatcacg tagtcgtggg gcgcgcccgc ggactcggcg gcatcggcca cctcgcccag 30181 atagcgcgcc gagggcagcc cgccctcgta gccgttgagg acgtacatcc aggccggctc 30241 ctcgccgtcc agcgtgtgca cccgcacccg catgcgccgg tagatgtcga ggccgacacc 30301 ctcccagcgg tccatggagt cctcgtccat cggagccagg tcgtagagcg cgacgaacac 30361 ctgggaacgg ggtgcctcca ccaccgtggc cagcgcgccc tcccagccca tctgctcccc 30421 gccgaacgtc agccgccagc cgttgagcca gcccgtgccg cgcagcgggg agtgcggtgc 30481 gcggcgcgtc atcagccgcg cgtcgaggtt gccggcgtac gcggcgtaga gcgacatggg 30541 gtcgagggta cgggaggtga cggggggcgt gccggttacg gcgaggatga ggcccggtcg 30601 tgggtggggg cgtgggcggc tccgccgggg ccggaggccg tggcccggcc aggcgcgttc 30661 ccgtatggag ggccccgggg cgaagcagct tggcgcgtgc gggacaatga attacgtact 30721 gcatacgccg gggcgatccc ccggaccccc ggccggggcg gcagacggcc gtgggatgac 30781 accacgcgag gcggactttt cgtgacccgg atcgtgatca tcggcggcgg ccccggcggc 30841 tacgaggcgg cactggtcgg cgcccagctc ggcgcggagg tgaccgtcgt cgactgcgac 30901 ggcctcggcg gcgcgtcggt cctcaccgac tgcgtgccct ccaagaccct gatcgcgacg 30961 gccgaggtga tgaccacctt cgactcctcc tacgaggaac tcggcatcat cgtcgccgac 31021 gacaccccgc acatggagca ggccgcccgg gtcgtcggcg tcgacctcgg caaggtcaac 31081 cggcgcgtca agcgcctcgc gctcgcccag tcccacgaca tcaccgcctc cgtcacccgc 31141 gcgggtgcca gggtcatgcg cggccgcggc cggctggacg gcctccaggc cgccgacggg 31201 tcccgtcagg tcgtggtgac cgccgccgac ggcaccgagg agcggctcac cgccgacgcg 31261 gtgctgatcg cgaccggcgg ccacccccgg gagatcccgg acgccctgcc cgacggcgag 31321 cgcatcctga actggaccca ggtctacgac ctggacgagc tccccgagga gctcatcgtg 31381 gtcggctcgg gcgtcaccgg cgccgagttc gccggggcct accaggcgct cggctcgcgc 31441 gtgacgctcg tctcctcccg cgaccgggtg ctcccgggcg aggacccgga cgccgctgcc 31501 gtcctggagg acgtcttccg gcgccgcggc atgaacgtca tggcccgctc ccgcgcccag 31561 tccgccaagc gcgtcggcga ccgcgtcgag gtcacgctgg ccgacggccg ggtcatctcc 31621 ggcacccact gcctgatggc ggtcggcgcg atccccaaca ccgcgggcat gggcctggag 31681 gagtccgggg tccagctcaa ggagtccggg cacatccgga ccgaccgggt ctcccgcacc 31741 agcgcccccg gggtgtacgc cgcaggtgac gtcaccggga tcttcgcgct ggcctcggtc 31801 gcggcgatgc agggccggat cgcgatgtac cacttcctgg gcgacgcggt ggcgccgctg 31861 aacctgaaga cggtctccgc gaacgtcttc accgaccccg agatcgccac cgtcggttac 31921 agccaggccg acgtcgactc cggcaagatc gacgcccgtg tcgtgaagct gccgctgctg 31981 cgcaacccgc gcgccaagat gcagggcatc cgggacggct tcgtcaagat cttctgccgg 32041 cccggcaccg gcatcgtggt cggcggctgc gtcgtcgcgc cgagggccag cgagctgatc 32101 cacccgatct cgctcgccgt ggacaacaac ctgacggtgg agcagatcgc caacgccttc 32161 accgtgtacc cgtcgctctc cggctcgatc gccgaagtgg cccggcagtt gcacacccgt 32221 aagaccgccg gcgaggcgta gcaccgaccg ctcgtacgga cgacagggcc ccctatatca 32281 ccagggggcc ctgtccatgt acaacttctg ttattcggcg caaactgctg aaaagcaacc 32341 tacggccagg ttactgtcag tttcgtgttc gctgcagaac gtcgtcaatt gatcctcgaa 32401 atggtgcgtg ccaacggggc ggtatcgctc cgtgagctcg cccgcgtcgt ccagacctcc 32461 gaagtgaccg tacggcggga cgtgcgggca ctggaggcag aaggactcct cgaccgccgg 32521 cacggcggtg cggtcttgcc gggcggtttt acgcgggagt ccggctttcc gcagaaatcc 32581 catctctcca ccgcggagaa gacggccatc gccgacctgg cggccgggct ggtcggtgag 32641 ggcgaggcca tcgtggtcgg cgccggaacg accacgcagg agctggcccg ccggctcgcg 32701 cgggtgccag gtctgaccgt ggtcaccaac tcgctgctgg tcgcccaggc gttggcgcat 32761 gccaaccggg tggaagtggt gatgaccggc ggcaccctcc gcgggagcaa ctacgcgctc 32821 gtcggcagcg gtgccgagca gtccctccag gggctgcggg tgagccgtgc cttcctctcg 32881 gggagcgggc tcaccgccga gcgcgggctc tccacgtcca acatgctctc ggcgagcgtg 32941 gaccgggcgc tggtgcaggc cgcggccgag gtggtggtcc tcgccgacca cacgaagctc 33001 ggctccgaca ccatgttcca gacggtgccc acggagctga tcacccgtct ggtgacggac 33061 gagccaccgg ctcacgacga gcgtgccgcc acggagctcc aggccctggc cgatcagggc 33121 gtggagatca ccgtcgcggg acccgacgcg gactccgggc cgggtgagcc gctgccgcaa 33181 gggcggcagg ggcggcagga gatgccgctg ccgggccagc ggcgtacgca gggcggccat 33241 ggcggccctg caggactggg cccccagctg cggagtgccg ccgcgctcgc ggacggcccg 33301 gtgggccggg tcgccgacct gcggcgccgg taggggagcg gagcccggcg cgggggcctt 33361 cggcgccggc agggggagtg aagcccggcg tggggacgtc gcgggtacgg cccggggacg 33421 tcgcgggtgc ggcccggggg agacttcgcg ggtacggccc gggggagact tcgcgggtac 33481 ggcccgggga ttttgcgagt acggcccggg gagggcctgt ccgtcagccg ccgggccggg 33541 gagagtcccc ccgtcagtcg ccgggccggg ccgagggtac ggggtcggct cgcagaccgc 33601 ggagcgtcag ccgcagcagc cggtcggcca ggtcgggatc ggccggggtc tgctccgcgg 33661 ccagcgcgat cgcgttcgtc agttgcagca ggtcgtcgat cgagacgtcc gcccgcaccg 33721 agccgctcga ctgcgcccgg gtcagcagcc ggtcgcccgc ctgacgcagc ggtacatggc 33781 aggacgtcag ggccgaagtc gcgtcccccg gcgccgacat gagcgcctgc gccagcccgc 33841 ggtacgcacc cgcatgggtc acgatcgcgc ccagccactc caccagcgcg gtgcacggct 33901 tgtcggacct ggccagttcg tgggagcggg cgagcagcga ggtcagggcc tcctggaaca 33961 ccgcgttcat cagggcctgg cggttcggga agtgccggta gagcgtgccg atgccgacgc 34021 ccgcccgccg ggcgatgtcc tccagcgagg catccgtgcc ctgggccgcg aaggacgtac 34081 gggcctcacc cagcagccgg tcgtagttgc ggcgcgcatc ggccgggccg gtgtcggtgc 34141 cgtgctcatc gccctcgccc tcttctcctg gtgtccgttc cgggtcccaa ggatgccact 34201 ggggcccggc ggtcgccggg ccccagtgac gaagagaacg cgcactcagt ccttgatctc 34261 gcagatcgcg gcgccggacg acaccgaggt gccgacctcc gccgccagac ccttcacggt 34321 gccggagcgg tgggcgttga ggggttgttc catcttcatg gcttcgagga cgacgatgag 34381 gtcgccttcc ttgacttcct ggccctcttc gacggcgatc ttgacgatgg tgccctgcat 34441 gggggaggcg agggtgtcgc cggaggcggc ggagccggac ttcttcgcgg cgcgccgctt 34501 gggcttggcg ccggcggcga ggccggtgcg ggccaggctc atgccgaggg aggagggcag 34561 ggagacttcc agtcgcttgc cgccgacctc gacgacgacg gtctcacggc ccgcttcctc 34621 gtccgtgtcc gtgtcggcgg ggacggtgta gggggtgatg tcgttgacga actcggtctc 34681 gatccaccgg gtgtggatgg tgaacgggtc ggcggtgaac gccgggtccg cgacaaccgc 34741 acggtggaac ggaatcgcgg tggccatgcc ctcgacctgg aactcggcca gggcgcgggc 34801 ggcgcgctgc agggcctgct ggcgggtggg ggcgggcggc ggctccgggc agccgcgccc 34861 gtcacgggac gtacgtacgg gggaaaaggc gccccccacc cgcaggcggg gatgagaccg 34921 tgggcggggg gcggttctcg gggtgcggcg gtcagtccgc cgcacggggg gcgggcggcg 34981 gctccgggca gccgcgcccg tcacgggacg tacgtacggg ggaaaaggcg ccccccaccc 35041 gcaggcgggg atgagaccgt gggcgggggg cggttctcgg ggtgcggcgg ncngtccgcc 35101 gcacgcacga cgacggcgga gttgaagccg ccgtagccgc gggccaccac cagcgccgta 35161 cgcacatcgg cggtgcgcgg gtgctcggtg accaggtcga tgccgtactc gtcggccggc 35221 cgggagttga ccgtcggggg gatgagccct tcctcgatgg ccagcagtgc ggtggccacg 35281 tccaggggcg ccgcgccgga gtagaggcgt ccggtcatcg tcttcggcgc ggtgacgggg 35341 acgcctctct cgccgaacac ctccgcgagg gcctgggcct cgacccggtc cagctcgggc 35401 acgccggccg cgtccgcgaa gaccacgtcc acgtcctccg gccgtacgcc cgcgtcgtcg 35461 agggcgaact cgatggcctt gcgcagcccg ggctcgcgtc cgctgcccgg cgcggcgtcg 35521 aaggtcgcgc cgtagccgca gacctcgccg tagacgcgcg ccccgcgttc atgggccgat 35581 tcggccgact ccatgatcag gatcgcgccg ccctcgcccg ggacgtaacc ggaggcctcg 35641 gcgtcgaacg gcaggaacgc gcgggccggt tcgtcgctgg tggtcagccg cttcgcggcg 35701 agctgcgcca cccagcccca ggggcagatg gaggcgtcga caccgccgga gacgatcatc 35761 cgggtgccct tgcggatcag ccggcgcccc tgggccaggg cgtccaggcc acccgcctcg 35821 tcgctgacga tcactccgct ggggcccttg agcccgttgc tgatggagat ctggccgctg 35881 ttgacggcgt agaaccaggc gaacgactgg tacgcgctga cgtactggct gccctggctc 35941 cacagcttct gcagctcgtt ctggccgaac tcgaagccgc cggacgagct ggccgtcacc 36001 acgcccatgt cgtactcggc gagttccttc gggtccacgc cggcgtcgtc gagcgcccac 36061 tgcgcggcga cgagcgcgag gcgggtcatc cggtccgtct gcggcagcat cctgctcggg 36121 agcagctcct ccgcggcgaa gccgggcacc tcccccgcga gggtcgccgg ataggacgag 36181 gcgtcgaacc gggtgacccg gccgatgccg ttcttaccgg cccgcgtggc cacccagtag 36241 tcccgtgtgc cgagacccgt gggcgcggtg atgcccagac cggtcactac gactgaggtg 36301 gtcatgccgc actcctctcg gggcgcgcca gcaccatggc gctctggaat ccgccgaagc 36361 cgctgcccac ggtcagcacc gcgtcggtga gctgctcccg cgccaccagc ggtacgtagt 36421 cgaggtcgca ctccgggtcc ggggtgtgca gattcgcggt cgggggcacg acgttgtgct 36481 ccatcgcgag tgcggaggcg gcgatctcga tggacccgat ggccccgagc gagtgcccca 36541 ccatggactt gatggagctg accggggtgc ggtacgcgtg gtccccgagg ctccgcttga 36601 acgccgcggt ctcgtgccgg tcgttctgct tggtgcccga gccgtgcgcg ttgatgtagt 36661 cgatctcggt cgcgttcacc cgcgcctcgc agagggccgc accgatcgcc tccgccatct 36721 ccttgccgtc ctgccgaaga cccgtcatgt ggtacgcgtt ggagcgggtg gcgtagccgg 36781 cgatctcggc gtagatgtgc gcgccgcgct tcttggcgct ctccagctcc tccaggacga 36841 acacggccga accctcgccc aggacgaagc cgttgcggga gctgtcgaag gggcgtgagg 36901 cgtgctcggg gtcgtcgtgc cggggggtgg tcgccttgat cgcgtcgaag cacgccatgg 36961 tgatcggcga gatcggggcg tccgaggaac cggcgatcat cacgtccacg gagccctcgc 37021 ggagcaggtc gacggcgtgg cccaccgagt cgatgccgga ggtgcagccg gtggagacca 37081 ccgtgctcgg gccctgcgcg cccacggccc aggcgacctc ggcggtgaag gagctgggca 37141 ccaggtagtt gtagaggtga gggaccgcgt actcgtggtc gaccaggtgc aggcggccgc 37201 cgtcgctgac cacgttgtac tcctcgtcga ggcccatcgt cgcgccgacg gcgctgccga 37261 tggtgacgcc gacgcggtac gggtcgtacg cggcgaggtc gatgccgctg tcggccacgg 37321 caccgcgcgc ggccaccacc gcgaactgcg cggcccggtc catgcgccgg atctcctgcg 37381 gccccagacc gtgctcccgg gggtcgaagt cgatctccgc ggcgacccgg gagcggaagg 37441 ggctcgggtc gaagaaggtg atcccgcggg tggctgtacg gccgtcactc agcaggtccc 37501 agaaggcctt cgccccgacg cctccggggg cgagcacctc gatgccggtg atgaccacgc 37561 gtcgcccgtt cacgcggaag cctcccagct gtagaagcgc ttcgccatcg cgtcggccgg 37621 ggagcgccag gtcgcggggt cgtacgcctc gatcagcggc ttgaggtcct cactgatctg 37681 ctggaagcgg tggtcgtggc gggcctcctg tatctgtcgc ccgccctggt cctcgtcgaa 37741 gtcctgcagg tggaaataga gaccgcggta ctcgaagagc tgccgccggc gcgtgcccat 37801 gcggtgaggc atttcggtgt cgtcgaagtc acggaaaatc ttggcgacat caatgctgga 37861 agcggtgtcc atacgagcca cgatcagagt gctgtgcatg ctttccctct cctcactgct 37921 catcaattca atttcagtat ccgaggcccg taaggggttt tcaacggtgc ttgtgtcagg 37981 gctttgtcag gccgtgcaag aattccgcag cacaaacaaa cggaatgccg ccactcagtc 38041 cttgatatcg catacggccg caccggagga aatcgatgtc ccgacttcgg cggacaggcc 38101 tttcacggtg ccggagcggt gggcgttgag gggttgttcc atcttcatgg cttcgaggac 38161 gacgatgagg tcgccttcct tgacttcctg gccctcttcg acggcgatct tgacgatggt 38221 gccctgcatg ggggaggcga gggtgtcgcc ggaggcggcg gagccggact tcttcgcggc 38281 gcgccgcttg ggcttggcgc cggcggcgag gccggtgcgg gccaggctca tgccgaggga 38341 ggagggcagg gagacttcca ggcgcttgcc gccgacctcg acgacgacgg tctcacggcc 38401 cgcttcctcg tccgtgtccg tgtcggcggg gacggtgtag ggggtgatgt cgttgacgaa 38461 ctcggtctcg atccaccggg tgtggatggt gaacgggtcg gcggtgaacg ccgggtccgc 38521 gacaaccgca cggtggaacg gaatcgcggt ngccatgccc tcnacnnnga actcggccag 38581 ggcgcgggcg gcgcgctgca gggcctgctg gcgggtcgcg ccggtcacga ccagcttggc 38641 caggagcgag tcccaggccg gtccgatcac gctgccggac tccacgcccg cgtcgaggcg 38701 gacaccgggg ccggtgggcg gggcgaagag ggtgacggtg ccgggggcgg gcaggaagcc 38761 gcggcccggg tcctcaccgt tgatccggaa ctcgaaggag tgcccgcgca ccgccgggtc 38821 gccgtagccg agctcctcgc cgtcggcgat acggaacatc tcccgcacca ggtccaggcc 38881 ggtgacttcc tcggtgaccg ggtgctcgac ctggaggcgg gtgttgacct ccaggaaact 38941 gatcgtgccg tccgccccga cgcgggcgtg gagtccggca gcgtgattgc gcgcggccga 39001 tgaggcgttc gctctgggcg gtgacactcc ggccgcgagc tatctggaca tggccaaggt 39061 gctgcaggcc gcgaaggatt ccggtgcgga cgcggtccac cccgggtatg gcttcctgtc 39121 ggagaacgcg gagttcgcgc aggcggtgct ggaggcgggt gttgacctcc aggaaactga 39181 tcgtgccgtc cgccccgacg aggaactcca ccgtgccggc gccgacgtag ccggcntcct 39241 tcaggatcgc cttcgacgcc gcgtagagct gctcgttctg ntccttggac aggaaggggg 39301 cgggggcctc ctcgacgagc ttctggtggc ggcgctgcag cgagcagtca cgggtggaga 39361 cgacgacgac gttgccgtgg gtgtcggcca ggcactgggt ctccacgtgg cggggcttgt 39421 cgaggtagcg ctccacgaag cactcaccgc gcccgaacgc cgcgaccgcc tctcgcaccg 39481 ccgagtcgta cagctcgggg atctcctcca gcgtgcgggc caccttcagc ccgcgcccgc 39541 caccaccgaa agcggccttg atcgcgatcg gcagaccgtt ctcctgcgcg aacgccacaa 39601 cctccgccga acccgacacc ggatccgggg tgcccgccac caggggggcg ccggcacgct 39661 gggcgatgtg acgggcggcg accttgtcac ccagatcccg gatcgcgtgc ggcggcggac 39721 cgatccacgt cagacccgca tccagcaccg cctgcgcgaa ctccgcgttc tccgacagga 39781 agccataccc ggggtggacc gcgtccgcac cggaatcctt cgcggcctgc agcaccttgg 39841 ccatgtccag atagctcgcg gccggagtgt caccgcccag agcgaacgcc tcatcaccac 39901 gtcagacccg catccagcac cgcctgcgcg aactccgcgt tctccgacag gaagccatac 39961 ccggggtgga ccgcgtccgc accggaatcc ttcgcggcct gcagcacctt ggccatgtcc 40021 agatagctcg cggccggagt gtcaccgccc agagcgaacg cctcatcagc cgcgcgcaca 40081 tgcagagcat cccggtccgg atcggcgtag acggctacgc tcccgatccc ggcatcccgg 40141 caagcccgag caacacgaac agcgatttca ccacggttgg cgatgagcac cttgcgcacg 40201 atgactccct ccttgagaac aagctgagtt tagggactac cgacacggcc gtacgacccg 40261 tccccaatag tgaacttgcc cacacggagt gtgatccgag gcttgctcgg gtcgcgaaat 40321 cccttgtcgc accacggtac gccgcgatcc tcaaccgcac agtagccacg aagtgtggcc 40381 caagtctctg tccggacgtt caacgccgcg cggcgtttct ttgtggactc cctacgaacg 40441 gacgagggaa tctttgccgc cgtgccgaag cggcggtacg ggcgtgcgaa gtgtgcacga 40501 cctcttgtcc ctgccattac cggttagtag ggtccgcgct gtaccggacg tactacaggt 40561 aacaaggggt gggtgccgtg gtgcgcagac cagtggccgt cgtgaccgcg atcgttctgt 40621 tcgtggaggc cgtgggcatc gtgctcgtca acggcgtcct cgcgacggtc gccgacaacc 40681 agagcatgtc cctggccggg atggatccgg acgccatggt caccggcaca tgggtgatgg 40741 gcggtgtctc cggggccctg ctggtgctct gcgggctgat accgctgctg gccgggatac 40801 gcgaccgggc gcccggccgc ctcggcagga tcgccctgat cgcctgcgcg gtcgtccacg 40861 gggtgctggg cgcgctggcg gtggggctga tcggctgggc ggccttcgct ttcctgatgg 40921 tcgtcctggc gctgatcgtg ctgaccctgg tggcgttcga ccggcgtgag ccggaagagg 40981 cgaagaccgg cccaggagcg gccccggagc cggtctgagg cccgctgagg gtctgctcgc 41041 tcagacccac aagtcggtga cggagacgcc cagttcgccg agcagtcggc gcagcagcgg 41101 cagtgagagc ccgatgacgt tgccgtggct gccctcgatc gactcgacga acggcgccga 41161 gcggccgtcc agggtgaacg ctcccgcgac atggagaggc tcacccgagg cgacgtaggc 41221 cgccacctcg gcgtccgtcg gctcgccgaa cctgacgacg gtggacgcgg tcgccgacgc 41281 cgtacggccg gtgcccgtgt cgatgacgct gtggcccgtc tgcaggatgc ccgaccggcc 41341 gcgcatggac ttccagcggg cggtggcctc ctcgctgtcg gcgggcttgc cgagcgcctc 41401 gccgtccagc tccagcaccg agtcgcagcc gatgacgagc gcgcccgagg cctccgggcg 41461 ggctgccacc gcggccgcct tcgcctcggc caggacgagc gccagctcac ccggggtcgg 41521 agcggtcagc gcgtcctcgt cgacaccgct gacgatcacc tcgggggcga agcccgcctg 41581 ccgcaggagg ccgagacggg cgggggaggc ggaggcgagc acgaggcggc gctgatcagt 41641 catacccgcc atcgtaggcg ggcccgaagg cccctcagcg ggtgcccagg acgaacatcg 41701 cgacgaccat ggccagcgcg agcagcagcc ccgcgcgacg catcatgtcc tgggcgtcgc 41761 gcagttcctt gggcggcttg ttctcggggt cggaccacag catggttccg atggtgctcc 41821 ggagacgaca gcggcgcctg agtacgcgta ctcaagcgcc gtccggcccg ttctcaggag 41881 ggccagtacg tccgcgccca ggagcggggc cccggccgga gcgcgccccg gcgggcgatc 41941 ctgcccgggt ccgaccactg ctcgggcggc agcggtgccc cggacggctc ggcggtcacc 42001 gccgccgcgc gcgcccggac cacggcgagg gccgcggcga gctcctccgg cgtcgggttg 42061 ccccgtacga ccttgatcat ggtgcctccc ggtggttaga gggggatgtt gccgtgcttc 42121 ttcggcggca gcgactcgcg cttcgtacgg agctggcgca ggcccttcac gaggtgcgcg 42181 cgggtgtcgg acggcatgat caccgcgtcg acgtagcccc gctcggccgc gacgtacggg 42241 ttgaggagtg cgtcctcgta gtccgccatc agctcggcgc gggtggcgtc ctggtcctcg 42301 gcagcggcga tcgtgcgccg gtgcaggatg ttgaccgcgc cctgcgcgcc catcacggcg 42361 atctgcgcgg tcggccaggc caggttcagg tcggcgccca ggtgcttgga ccccatgacg 42421 tcgtacgccc cgccgaaggc cttgcgggtg atcaccgtga tcagcgggac ggtggcctcg 42481 gcgtaggcgt agatcagctt ggcgccgcgc cggatgatgc cgccgtactc ctggtcgaca 42541 ccgggcagga agccgggcac gtcgacgaag gtgatgaccg gcacgttgaa cgcgtcgcag 42601 gtacggacga agcgcgaggc cttctcgctc gcgtcgatgt ccagacagcc ggccagctgc 42661 atcggctggt tggcgacgat gccgaccggg tagccctcga tgcgcccgaa gccggtgacg 42721 atgttcggcg cgaacagggc ctgggtctcc aggaactcac cgtcgtcgag cacgtgctcg 42781 atggcggagt gcatgtcgta cggctggttc gccgagtccg ggatgagggt gtcgagctcg 42841 cggtcctcgt ccgtggtctc caggtcggcc tcctccggga aggcaggggc ctccgagagg 42901 ttgttcgagg ggaggtagga cagcagggac ttgacgtact cgatggcgtc cttctcgtcg 42961 ccggccatgt ggtgggccac gccggacgtg gtgttgtgcg tacgggcgcc gcccagctcc 43021 tcgaagccga cgtcctcgcc ggtgaccgtc ttgatgacgt cggggccggt gatgaacatg 43081 tgcgaggtct ggtcgaccat caccgtgaag tcggtgatcg cgggggagta gaccgcgccg 43141 cccgcgcagg gcccgacgat cagggagatc tgcgggatca caccggaggc gtggacgttg 43201 cggcggaaga tctccgcgaa cagcccgagg gcggccacac cctcctggat gcgtgcgccg 43261 ccgccgtcgt tgatgccgat gaccgggcag ccggtcttca tcgcgaagtc catgaccttg 43321 acgatcttct cgccgtagac ctcgccgagc gagccgccga agatcgtgaa gtcctgcgag 43381 tacacgcaga cgggacggcc gtcgaccgtg ccgtagccgg tgaccacgcc gtccccgtaa 43441 gggcggttct tctcgatgcc gaaattggtg gaccggtgcc gtgcgaattc gtcgagctcc 43501 acgaaggagc cctcgtcgag caggagatcg acccgctccc gggcggtcaa cttgcccttg 43561 gcgtgctgct tttcgacggc acgggcggaa cctgcgtgtg tggcctcttc gatacggcgc 43621 tgcaggtccg cgatcttgcc cgcggtggtg tggatgtcgc tctgcggctc ggacatcggg 43681 tggcggctcc ctgcctggtc acggggacgg ctggtacatc tggtgcatcc agtaccgtgc 43741 tcgacggctg gctgctcgtc ggcgggtggt tgctactgac ccgtagcgta tcggcgcgga 43801 tacggttcgg cagtgcgtcg ttggccacac ctaatgtggg ttgcatgaca cctccggatg 43861 cgccgcacaa ccgctggtcg gacctcgaca ggccgcccct gaacgccacc gcgctgcgcc 43921 gcgggctcct gaagcccgag ggcctgtgga cctcgctcga catcgtcgag gcgaccggct 43981 ccaccaacac cgacctcgtg gcacgggcct ccggcggcgg cctggccgaa ggcgcggtgc 44041 tggtcgcgga ggagcagacc gcgggccgcg ggcggctcga ccggagctgg acggccccgc 44101 cccgctcggg cctcttcctc tcggtctacc tcacccccgg tgacgtaccc gccgagcggt 44161 ggggatggct gccgctgctg gccggtgtcg ccgccgccac gggcctcgcg cagtcggcgg 44221 gcgtggacat ggcactgaaa tggcccaacg acctcctggt gaccatcggc ggcaccgagc 44281 gcaagaccgg cggcatcctc gccgagcgcg ccggcgacgg ggtcgtggtg ggcatcggcc 44341 tcaacgtgtc gctgcgcgcg gccgagctgc ccgccccgca cgccggttcg ctggcgctcg 44401 ccggagccgt ctccaccgac cgcgagacct tgctccgggc cgtcctgcgt tcactggaac 44461 agtggtacgt gcagtggcgc gacgcgaacg gcgacgccgc cgagagcggc ctccaggccg 44521 cctacgcggc gggctgcgcc acgctcgacc ggacggtgcg ggccgagctg ccgggcgacc 44581 gcaccctcgt cggagaggcc gtcgcgatcg acggcgacgg acggctcgtg ctggccacgg 44641 gcgacggcct ccaggagccc gtgtcggccg gggacatcgt ccacctgcgc ggggaggagg 44701 gcggtctcac ctgatccacc gcccccgcac gcacgcgtgg tgccacgcgt gcgtgcggga 44761 cgccggatca ggtgagaccg cgccaccggg gacgtgagcc agggcacacc tgccgtatcg 44821 ttgaggcgat ccagcgacag atcggcaggg cagtgcgcag ggaacgggca ggaggcggcc 44881 ggtgaccgtc gacgacacga actccgacga cggcgcggag ccctcgtcgg gaccgtccgt 44941 ccactcgaca ccgcatcacg aggtcgacca cacggccgaa ccgaccgacg accctctcgc 45001 gatcaggctg gaacagctga tcctgggggc cgaccgtcgc tacacgccgt tccaggcggc 45061 caggaccgcc ggggtctcca tggacctggc gtcccgcttc tggcgggcta tggggttcgc 45121 cgacatcggg caggccaagg cgctgaccga ggccgacgtc ctggcgctgc gccgcctcgc 45181 cggactcgtc gaggccgggc tgctcagcga gccgatggcg atccaggtgg cccggtcgac 45241 cgggcagacc accgcccggc tcgccgagtg gcagatcgac tcgttcctgg cggggctgac 45301 cgagcccccc gagcccggaa tgacccgcac cgaggtcacg tatccgctga tcgagctgct 45361 cctgcccgag ctccaggagt tcctggtcta cgtgtggcgg cgccagctcg ccgccgccac 45421 gggccgggtc gtgcagaccg gggacgacga ggagatggtc gaccggcggc tcgccgtggg 45481 cttcgccgac ctcgtcggct tcacccggct gacccggcgg ctggaggagg aggagctcgg 45541 cgagctggtc gaggccttcg agacgacctc ggccgacctg gtcgccgcgc acggcgggcg 45601 gctcatcaag accctgggcg acgaggtcct cttcgccgcg gacgacgcgg gcacggcggg 45661 cgagattgcg ctccggctgg tcgaggtgat ggcccaggac acgacgatgc cctcgctgcg 45721 ggtcggcatc gcgttcggca cggtcaccac gcgcatgggc gacgtgttcg gtacgacggt 45781 gaacctggcc agtcggctca cgtcgatagc gcccaaggac gcggtgctgg tcgacggcgc 45841 gttcgccgcg gagctcatca ggaacggcga cgcccccgcc tccgaggccg aggagaccgc 45901 cgcggcggcc gagcgggccc ggctggcgga gaaggaggac cgccgcccgg acgaggagcc 45961 cccgcacccg tcgtaccgct tcggactgca gcccatgtgg cagcggccgg tgcgcggcct 46021 gggcgtggtg gagccctggc tgctggcccg gcggggcaag ccctcgacct gacggacggg 46081 tgccggaaag gcctgcccct aggattccgg taacgctcgt taaccggagg ggttcagtca 46141 tgggtgtcac gtcggagcag cggttcgggg agttcgtcgt cgtacggcgg cacgagggcc 46201 aggaccacgt cgcggagctg gtgctcgacc ggcccgaggc gatgaacgcc gtgagcaccg 46261 cgatggcgcg gtccgtcgcc gaggcctgcg ccgcgctcgc cgccgaccag ggggtgcggg 46321 ccacggtgct cacctccagc catgagcgag ccttctgcgt gggcgcggac ctcaaggagc 46381 ggaactcctt caccgacgcc gagctggtgc ggcagcggcc cacggcacgg gccgcctaca 46441 ccggcgtgct ggagctcccg atgcccgtcg tcgccgccgt gcacggcttc gccctcggcg 46501 gcggcttcga gctcgcgctg gcctgcgacg tgatcgtggc cgaccgcacg gccgtggtcg 46561 gcctgcccga ggtgtccgtc ggtgtcatcc ccggcggcgg cggtacgcag ctgctgcccc 46621 gccggatcgg ggccgcgcgc gccgccgagc tggtcttcac cgcccggcgg gtggaggcgg 46681 ccgaggcgcg cgagctgggc ctggtcgacg agctggtcga ggcgggccgg gaccgtgagg 46741 aggcgctggc gctcggcgcc cggatcgcgg cgaactcgcc ggtggggctc cgggcggcca 46801 agcgggccct gcggctgggg caggggctgg acctgcgggc cggtctcgag gtggaggacg 46861 ccgcctggcg gtccgtggcc ttctccgggg accgggccga gggggtcgcc gcgttcaacg 46921 agaagcggaa gcccagctgg cccggtgagt gagcccggcc ggcggagccc gggagcgatc 46981 tgaagatcat cagcgctgcc aactgatcaa atcatcacaa acctccctaa gctggggcga 47041 tgggcggtga tgatgcgcgg ctgcgcgccg tggttgcgct ggcacagacg atggcggcgg 47101 cctacacccc gcacgagtcc tggcacgccg cggcgatggg ggcgtgcgag gcgctggggg 47161 gcagtttcgc cgccctctcc gtgtgggagc gggaccaggg caggctgcgg gtgctggtga 47221 acgcggggga gcgggccgag ggggaggagg agttccccga ggacgaggcc tacccggtgc 47281 accagttccc ggagatcacc gagttcctgc acgagcgctg ggcgggcggc ggtgaacccg 47341 acgcctgggt ggagaccgcc gccggcgccc cggccgccgg ggcgccggcc aggggtgccc 47401 ggccgtactg ccaccagcgg gtcgccgcgc tgcgccggcg cgggcggggc tgctgcgtgg 47461 tggcgccgat cgtgctgcac ggaagggcct ggggtgagct gtacgtggcc cgccccgcgg 47521 gggcccccgt cttcgaccgg gacgacgcgg acttcgcgac cgtgctggcc gccgtcgtgg 47581 cggccggcat cgcgcagacc gagcggctgg aggaggtccg caagctggcc ttcacggacc 47641 cgctgaccgg cctggcgaac cgcagggccg tcgatctccg tctcgacgag gcggtggacc 47701 ggtaccgcac cgagggggcc gtggtcagcc tggtggtctg cgatctgaac ggcctcaaga 47761 cggtcaacga cacgcacggc cacgcggtcg gcgaccgtct gctggaacgt ttcggctccg 47821 tgctctcgct ctgcggcgcg atgctccccg gcgccctggc cgcgcgcctg ggcggcgacg 47881 agttctgcct gctggccgtc gggcccccgg cggacgacgt ggtccgggtc tccgaggagc 47941 tctgcgcgcg ggccgtcgcc ctggagcccg gcgacggcgt cgcctgcggg gtcgcgtcca 48001 ccggcgacga catcggcccg gtccagtccg cgcgccggct cttccggctg gcggacgccg 48061 cccagtacca ggcgaaggcc gcgcgctccc ggagaccggt ggtcgccggg cgcgacggcg 48121 acgtgatccg gctcgcggac tccccgcccc ggtcccccca cgaccgccgc aggctgcgcg 48181 gcaacccgcc cggtggcgat cggtaagggg tcaaccccgc gaccactggt gacatgacgg 48241 ctttcagtcc gtacgcttct gaatatggat atgcatacag tcgtggtggg gacgtccgga 48301 accaccgccg aggacgtcgt cgccgtggcc cgccggggcg ccagggtcga gctctcaccg 48361 gccgccgtcg aggcgctcgc cgccgcccgg gagatcgtcg acgccctggc cgccaagccc 48421 gagccggtct acggcgtctc caccggcttc ggagccctgg ccagccggca catcagcccg 48481 gatctgcggg cgcagctgca gcgcaacatc gtccgctcgc acgcggccgg catgggcccc 48541 cacgtggagc gcgaggtcgt ccgggcactg atgttcctgc ggctcaagac gctcgcctcc 48601 ggccacaccg gcgtacggcc ggaggtcgcg cagaccatgg ccgacgtgct caacgcgggc 48661 atcacccccg tcgtccacga gtacggttcg ctcggctgct ccggcgacct cgccccgctc 48721 tcgcactgcg ccctgaccct gatgggcgag ggtgacgcgg agggccccga cggcgtcgta 48781 cgccccgcag gagagctcct cgcggcgcac ggcatcaccc ccgtcgagct gcgcgagaag 48841 gagggcctcg ccctcctcaa cggcaccgac ggcatgctgg gcatgctcgt gatggccctg 48901 gccgacctca ggaacctcta caccagcgcg gacatcaccg ccgcgctctc cctggaggcc 48961 ctcctcggta cggaccgggt cctcgccccc gagctgcacg cgatccgccc gcaccccggc 49021 cagggcgtct ccgccgacaa catgctgcgg gtgctcgccg ggtcgggcct caccggccac 49081 catcaggacg acgcgccccg ggtccaggac gcctactccg tgcgctgcgc cccccaggtc 49141 aacggcgccg gccgcgacac cctcacgcac ggcgcgctcg tcgccgaccg cgagctggcc 49201 tcggcggtgg acaacccggt cgtgctgcct gacggaaggg tcgagtccaa cgggaacttc 49261 cacggcgcgc ccgtcgcgta cgtcctcgac ttcctggcga tcgtcgccgc cgacctcggc 49321 tcgatcaccg agcgccgcac ggaccggctg ctggacaaga accgctcgca cggcctgccg 49381 ccgttcctcg ccgacgacgc cggggtcgac tccgggctga tgatcgccca gtacacgcag 49441 gccgccctgg tcagcgagct gaagcggctc gccgtaccgg cgtccgtcga ctcgatcccg 49501 tcctccgcga tgcaggagga ccacgtctcc atgggctggt cggccgcgcg caagctccgt 49561 acggccgtca cgaacctcgc gcggatcgtc gccgtcgagc tgtacgccgc cacccgcgcc 49621 gtcgagctgc gcgccgccga ggggctgacc cccgggcccg ccgcgcaggc cgtcatcggc 49681 gcgctgcgcg ccgccggggt ccaggggccc ggccccgacc gcttcctctc gcccgacctg 49741 gaggccgccg acgccttcgt acgggagggg aagctggtcg cggccgtgga gacggtgacc 49801 ggcccgctgg cctgagcgtc ccggcccgta cgcgcgaggg ctgccgcacc ccggggatgc 49861 ggcagccctc gcgtacctca gaagccggtg ccctgcgccg agccacggcg catcgagtac 49921 acgacgaacc ccgcgccgac gcacagggag gccgtgccgc cgatcaggta gggcgtcgtg 49981 tcgatgcccg tcccggtgtc ggcgagcgtc tcctgggagg tgaactcccc cgtggcggag 50041 gcctggcgga cctccgtcga ggaaccggcg gacgagccgg ccgaaccgct cggtgcgccc 50101 gtcccgcccg tcgcgttcgc ggaggggacg aaccagagag cacagagcag ggtgcctgcc 50161 gctgtggtgg tcagcagcgt gcgacgagcg atggacacag aatcgatccc cttgcgacaa 50221 ccatcagttg aggccgttcg tttggatcat gccggatcag ggagcggggt gatccaaacg 50281 aaaggccttg gccccgtggg ccgatgctaa gcaaagcagc gggtcggtgg aaagccgcgg 50341 gtcccgggag ccttacgctc cggcgtatga gcacttcgga gacaccctca tttgttcggc 50401 ttcgcgtgga gatggtgctg gagatcagcg acgcggacgc cctgaccgga acggcgctgg 50461 agagcatcgc cgccgacttc accaccaccg gcgcctcggc cgacgagtcg gccgaggaac 50521 gtacgcatgc cgaggagacc gtcagggaag acgcagcgga ggccctcgcc tcgctgatcg 50581 accccttcga tctggtgagc caggtacccg gggtcgagct cgcccaggcc tcctggagca 50641 gcgagacgat cgactacgac cccgacgccg aggactggac cgccggagag gacggggacg 50701 aggcgtacta cgggatcgag gacaatgaga cggacgacga agaaggcggc gggaacacgg 50761 aacgctgacg ctgccggggc actcctcaca gggggcggga accgccgccg ttccgggtgc 50821 gtcgatgagt ggtgttcccc acatccgcgg tggatgtgga acggaagacc cggtcacggt 50881 gttcttggaa cattgacggg gaatcgccgt cgggcgaccc tgtccgggga tcttggggaa 50941 tcggcaacga tggagaagct tgtgatgacg gacagcaagc ggcgcagggg cctcatggcc 51001 gcgtccgcac tgctcggcgg cgtgctggtg ctttcggcct gtagcgacga cggcggtgac 51061 agcggcgcga gcgccgacag ctcgaagacg tcacaggcgc aggtggacga ggcggccgcc 51121 aaggacgcct ccgaggcgca gataacgatc gcgccgaaga acggtgcgac caacgcgagc 51181 atcaacaacg ccgccatggt caccgtcgcc aaggggaagc tgaccgaggt caccatgacc 51241 tcggccgacg gcgacgccgt cgagggcacc ctcgcggccg acggctccag ctggaagccc 51301 agcggccagc tcgagcgctc cacgacgtac aagatcagcg ccaccgcggc ggactccaag 51361 gggcgcgagg cgcacggcaa cagctccttc accacggtct ccccggagaa cagcttcatc 51421 gggaacttca cccccgagga cggctcgacc gtcggcgtcg gcatgcccgt ctcgatcaac 51481 ttcaacaagg cgatcaccaa caagaaggcc gtccaggacg gcatcaaggt gacgtccagc 51541 agcggccagg aagtcgtcgg ccactggttc aacaaccagc gcctcgacct gcgccccgag 51601 gactactggc agggcggctc caccgtcacg ctgaagctgg ccctggacgg cgtcgagggc 51661 gccgacggcg tcgtcggtgt gcagcagaag acggtcacct tcaaggtcgg ccgcaaccag 51721 gtctcgaccg tggacgccaa ggcgcacacc atgacggtca cccgggacgg caagaccgtg 51781 aagaccatcc cgatctccgc cggatcctcc gacaacccga cgtacaacgg ccagatggtg 51841 atctccgaga agttcaagga gacccgcatg gacggttcga cggtcggctt cacggacgac 51901 gacggcaagg gcgagtacga catcaaggac gtgccgcacg ccatgcggct ctccacgtcg 51961 ggcaccttca tccacggcaa ctactggggc gccaagtcga tcttcggcag cgcgaacacc 52021 agccacggct gtgtcggcct ctccgacacc cagggtgcgg acgaccccaa cacccccgcc 52081 gcgtggctgt acgacaactc gatggtcggt gacgtggtca tcgtcaagaa ctccccggac 52141 aagaccatcg ccccggacaa cggcctcaac ggctggaaca tgagctggtc ggagtggacg 52201 gccaacgccg cctgacctcc tgaccgcgcc cctctcccca ccgaaggcgg cggcacccgg 52261 acctttccgg gcgccgccgc cttcggcgtg tgcggacggc ggtgcaggcg ccccgtcggt 52321 gttctcatcc agctctcatc ggagacttaa ctcctcatca cgcccgctcc atatcttcgc 52381 gccatgttct tcacctacct ccggcgcgag ctgcgccgcc gcagaaaggc ggcgctcgtc 52441 gtcgcctcgg ggctcgccct cggcattgcg ctcgtcatca tcgtcagctc ggtctcctcg 52501 ggcatgagca aggcccagga caaggtcctc gaatcgctgt acggcctggg cacggacatg 52561 acggtgacca aggccgcggc cgccccgggt tccggcggca ccgagcggcc caagttcgac 52621 ttcgacgcca aggacgacga cgaagcgacc cagagcacgg accgcgtgat ggtccagggc 52681 ttccagacgc tggcctccag caccgtcgac aaggtgggcg agcaggacgg cgtcgtggac 52741 gcggtgggcg ggctgagcct gaccgtcatg aaggtcgacg gccagttcaa gcgaggcgag 52801 ttcaagcagg acgagagcgc gtcccagggc ggccccggcg gccggggcgg cagcggcggc 52861 ggccagccgc agggtgaggt ccagggcggc ggagcatcct tcgacgtcaa ctccttcacc 52921 gtgtacggca ccgacgtcac ccagcaggac ctcggcccgc tgacctcctc caagatcacc 52981 gagggccgta ccttcaaggc caccgagacc gacgcgaagg tcgcggtcgt cgactccgcc 53041 tacgccaagg agaaggagct cgcggtcggc aggaccgtgg ccgtctccgg caccacgtac 53101 aagatcgtcg gggtctccac ggcggacagc ggcgacgcgg cggccaacgt ctacatcccg 53161 ctgaagcagg cgcagaccgt cgcggactcc aaggacaagg tcaccacggt ctatgtccag 53221 gccgccgact cgcagaagat cgacaccgtc aaggccgcca tccagaagaa catctcgggc 53281 acgacggtca ccacctccgc cgacctcgcc gacacggtgt ccggctccct ctccaccgcc 53341 tccgacctgg cctccagcgt cggcaagtgg ctctccgtcg cggtcctgat cgcggcgttc 53401 ctcgtcgccg gcctgctcac gtcctccgcg gtcagccgcc gggtgcggga gttcggcacc 53461 ctcaaggcgc tcggctggaa gagcggacgg gtcacccgcc aggtcgtcgg agaagccctc 53521 gtcaacggcc tgatgggcgg cgtcctcggt atcgccgtcg gcgtcgccgg cgcctacgtc 53581 gtcacggcca tcagccccac cctcaccgcc cagctcggct ccaccggcgg gggcggaggc 53641 ggcatgggtg gcggcggccc gatgggcggc ggcggaggcg gccgtcagac cgcgtccaag 53701 accctggaca tcgcactgac cgcacccgtc tccctcacca cgatcctcat cgccgtgggc 53761 ctggcggtgg cgggcgggct catcgcggga gccttcggcg gctggcgtgc ctcccggctg 53821 cggccggccg acgcactgcg ccgcgtcgcg tagatccacc ctcccctccc gtacgtacag 53881 caggagtcca cacgtgtacc agctcaaggg cgtcaccaag cgctacatgc gcggcaagaa 53941 tcccgtcgac gcgctcgccg gagtcgatct gaccatcgag gacggcggac ggctcgtcat 54001 ccagggcccc accggcgggg gcaagtccac gctcctgcag atgctcggcg gactcgaccg 54061 gcccacctcc ggcaccatcg agctcgacgg tgtcgacctg gccaagctcc ccgagtcccg 54121 gctcaccaag gtccgcgccg agtccatcgg attcgtcttc cagagcttca acctgatccc 54181 gacgctcacc gcccaggaga acgtcgagac cgcgctcgtc cccctcggcc tcggcgcgaa 54241 gatccgccgc gagcgggccg cggaggccct ggagtcggtg ggcctcggcg accgccccac 54301 ccacctgccg agcgagatgt ccggcggtca gcagcagcgc gtcgcgatcg cgcgggccct 54361 ggtgaagcgg cccaaggtgc tgctcgccga cgaaccgacc ggcaacctcg acgagtccat 54421 gcgcgacgag atcatggagc tgctcgacgg gctgtggaag gagcacgggc tcaccttcgt 54481 gatggtcacc cacgacagct ccctcgcccg taaggcaccc agggtggcga ccatccgcaa 54541 gggcagggtc accgtgacgg agaacgcggc ggcctgaccc ccggccgccg ccggacctca 54601 cggccgtcct cctccggctg tgaggttcgc cacccgcacc gccccgccgt gcgggtggcg 54661 cgcggggcgg tgcgcgaggt cctcgaaacc ctgggccccg tgctggcgca gcggccggag 54721 ttcgtcgacg cccggatcat cgagcgcatc tgcgagcccg agcggcagct catcttccgg 54781 gtgccgtggg cggacgacgc cggcggcatc cacgtcaacc gcggcttccg cgtcgagttc 54841 tccagctcgc tcggcccgta caagggcgga ctgcgcttcc acccctccgt caacctcggc 54901 atcgtgaagt tcctcggctt cgagcagatc ttcaagaacg ccctcaccgg catgccgatc 54961 ggcggcggca agggcggtgc ggacttcgac cccaagggcc ggtccgacgc cgaggtcatg 55021 cggttctgcc agtcgttcat gacggaactc caccgtcacc tgggcgagta caccgacgtc 55081 cccgccggtg acatcggcgt cggcggccgg gagatcggct acctcttcgg ccagtacaag 55141 cggatcacca accgctacga gtccggcgtg ctcaccggca agggcctcgg ctggggcggc 55201 gcccaggccc gcaccgaggc gaccggctac ggctgcgtcc tgttcaccgc cgagatgctc 55261 cgcgtgcgcg gcgagtccct cgaaggccag cgcatcgcgg tgtccggctc cggcaacgtg 55321 gccatctacg ccatcgagaa ggcccagcag ctcggcgcga ccgtcgtgac ctgctccgac 55381 tcgggcggct acgtggtgga cgagaagggc atcgacctcg cgctgctcaa ggaggtcaag 55441 gaggacggcc gcggccggat ctccgagtac gccgagcggc gcggcgacca tgtgcgctac 55501 gtccccggca cgggcgtctg gagcgtcccg gtggacgtgg ccctgccctg cgccacccag 55561 aacgaactcc acgaggagga cgcgctggcc ctcgtacgca acggggtcaa ggcggtcgcc 55621 gagggcgcca acatgcccac cacccccgag gccgtccacg tcctccagga cgcgggcgtc 55681 gccttcgccc ccggcaaggc ggccaacgcg ggcggggtgg ccaccagtgc gctggagatg 55741 cagcagaacg cctcccgcga ctcctggacg ttctcccaca ccgaggagcg gctggcggag 55801 atcatgcgcc acatccacga ctcctgctac accaccgccg agaagtacgg cagccccggc 55861 aactacgtgg tgggcgcgaa catcgcgggc ttcgagctcg tcgcggacgc catgctggcg 55921 cagggcctga tctgaccccg ccgcaccggg ccgggggcat cgagcccccg gcccccgcgc 55981 cggtgctacc ggcgcctgaa gtgctccgcg cagcccgtgt tcgccaccgt caccacggcg 56041 agcacgacgg ccgccaccgg gtggcccgtc ccgtggaccg ccgcgacgcc gccgccgagg 56101 accagggtct tcacggccag cacccccgcc aggggcagcg ggtaccgggc gcgtggagcg 56161 gcgaacagcc cccacagcac gacggccgcc accggggcgc cgatccccag ggccaccgac 56221 gccgcgacgc cctccggggc cgtgaaaccc cacacggcga gagcgccgat cgcgaccagt 56281 tcgacgacga acgcgagtgc ctcgttcgcc gcgaaccagg gccggccgcg cagagcggtg 56341 agatgtctgt ggtcctcgtt cgcggtcatc ggttctgaac ccccctgtac gggccgtacg 56401 gacgccccca ggatgccccg cccacgtacg ccgggcggtg cggttcggtg acaaccgccg 56461 ttctgccgac agcagatccg cccggcgcgg acggccgacc gctcccgtac cgggcacacc 56521 gctcctaggc tggggcgatg agcagccacg cgaccggccg agcccgcgtc atccccctgc 56581 gccccgtcca cgccgcaccg gcccccgccg ctgccgccaa ggagccgctc tggcgggacg 56641 tcgtcggcga tgtcctgcgc cgtgagcgca ccgcccagcg gcggacgctc aaggacgtgg 56701 ccgaggccgc ccgcatctcc atgccgtacc tctccgagat cgagcgcggc cgcaaggagg 56761 cctcgtcgga ggtgctcgcc gcggcggccc gctcgctggg gctcgggctg gccgacgtgc 56821 tgtccctggc ccaggacgag atcgcccgcc gcgcaccgtc ccgcacggct ccggcgcggg 56881 ccccgatggg cgaggtgcgc ctggccgcct gacccgccgc ggacgtgggc ggcgggccac 56941 gccgggcggg cggcgtccgg tgccggcgtc cggtgccggc gtacgttcag gcggcggcca 57001 ggacccggcg gctgagcacc tcgtccgcca ggccgtacgc caccgcctcc tcggcggccg 57061 gccaggagga ccgccgcggt cgaggcggcc tggccgacgc agaacgtcgc gatgggagcc 57121 gagacgaagc tcatcgtgtc gtagatcgcc atgagcgagg tgaacgagcc gccgggagag 57181 ttgaggtaga ccgcgatctc acccccgggg ttcgacgact ccaggtggag cagctgggcg 57241 atgacgacgt tggcgacccc gtcgtcgatc tccgtaccga tgaagatgat ccgctcggac 57301 aggagccggc tgaacacgtc gtaggaccgc tcgccctgcg gggtgcgctc gacgacgttc 57361 ggaatcgtgt actggcccat gtcagagtcc catccgtcgt cgtgaaccgg ccgggcgcac 57421 gtcgtcgagc gactcgacga cgtggtcgac catgccgtac tccttggcct gcccggccgt 57481 gaaccagcgg tcgcggtcac cgtcccggga gatcgtctcc gcggactgcc cggtgtgcgc 57541 cgcggtgatc cgctcgaccg cctgcttcgt gaactcgagg ttctccgcct ggatcgcgat 57601 gtcggaggcg gtgccgccga tgcccgccga gggctggtgc atcatgatcc gcgcgttcgg 57661 cagggcgtac ctcttgccct cggtccctac ggtgagcagg aactgcccca tggacgcggc 57721 gaatcccatg gcgagggtgg agacgtcgtt cgggatgagc tgcatcgtgt cgtagatggc 57781 cagccccgcc gtcaccgagc cgccggggct gttgatgtac aggctgatgt cggtgcgggg 57841 gtcctcggcg gacagcagca gcagctgggc gcagacccgg ttggcggaga cctcgtccac 57901 ctgggtgccg aggaagacga tccgctgggc gaggagctgg gcggcgaggt ggtcgtcgaa 57961 ccgtgtcgac ggtgtgtcct cgtcggcggc tcggtgacgg cggggctggc catctacgac 58021 acgatgcagc tcatcccgaa cgacgtctcc accctcgcca tgggattcgc cgcgtccatg 58081 gggcagttcc tgctcaccgt agggaccgag ggcaagaggt acgccctgcc gaacgcgcgg 58141 atcatgatgc accagccctc ggcgggcatc ggcggcaccg cctccgnnnn nnnnnnnnnn 58201 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn 58261 nnnnnnnnnn nnnnnnnnnn nnnnnnccac ccacgcgccg ccgacgagga cacaccgtcg 58321 acacggttcg acgaccacct cgccgcccag ctcctcgccc agcggatcgt cttcctcggc 58381 acccaggtgg acgaggtctc cgccaaccgg gtctgcgccc agctgctgct gctgtccgcc 58441 gaggaccccc gcaccgacat cagcctgtac atcaacagcc ccggcggctc ggtgacggcg 58501 gggtggggcg acatcgggcc ncccggtgag gggcggcggc ctgggcggcc gcgttccctc 58561 cactcttggc ccacccgggc ccccgcatca cgcatatctg cccgcggcag atatgccgcg 58621 ggcagagggt gattccgggc ggccgtccca ccgccccggg ccggccgccc cacgcggccg 58681 gctccgtcag gtcactcgga ggcgctgggc gccggggcga tgcccgtcgg gcaggcgcgg 58741 ccccagttgg tctccgaggg ggactccagc gtggcgcccg tgccgccgat gccgcagtag 58801 ccgtcggggt tcttgtcgag gtactgctgg tggtacggct cggcgggcca gaaggtgcgg 58861 ccctcggccg gcaggatctc cgtggtgatc tccttgaagc cggcgcccgt cagcacctgc 58921 tggtacgcct cgcgggacgc ctgcgcggcc tccgcctgct cgggggagtg ggtgtagaga 58981 gccgagcggt actgcgtacc cacgtcgttg ccctggcgga agccctgggt cgggttgtgg 59041 gactcccaga agaccttcag caggtccgcg tagctgacga ccttcgggtc gaagacgaca 59101 cggaccgcct ccgtgtggcc ggtcaggccc gagcaggtct cctcgtacga gggattctcg 59161 gtgtagccgc cctggtagcc gacgagcgtc gtccagacgc cctccgtctg ccagaacttg 59221 cgctcggcac cccagaaaca gcccagcgcg aagtcggcga cctccaggcc ctgcggatac 59281 gggccggtca gcgggttgcc gaggaccgtg tggcgggacg gcacggtgaa ctcgggggtg 59341 ggacgaccgc gcagggcctc ctccggggtg gggagctgcg gggtgcggtg ggtcaggaac 59401 atgcgggggc tcctccgggg tcggggttcg ctccgtacaa cgccgcgggg gcgccgtgga 59461 ttccgggtct caggccgcgg gggccggggg atcgcggcgc tcgccggcct cgcggtccgg 59521 gccggtggcg cggtccggac cggcctcgcg gtcaccgccg gccggtgact cgtaggaggc 59581 catgtacgcg gcggtcttcc tgcgggcccg cagccagaac cagacggcga gggctatcag 59641 gatcagcggg atcagtcgtg ccatgggtgt gccggtccaa tccggagggg gcaggtcgtg 59701 ccggggtcag tggagcagcg tcgcggggct gccgccgttc gcctcgtacc cggcgacggc 59761 cagcgcccgg tacaccgtgt actcggcggc cgggtcggag ctctgggtcc agggcagcgc 59821 gcccacatgg ccgtcgatgt ggacgagctg gtgcatcgcc tccgaccagc gttccatgcg 59881 gaccaggaag aggaccagca ggtgccggac gtgggcgagc atcgggtcgt cggcgcgcgc 59941 cgcgtgcacc gcgaacatcg cgccctcgac cgccttcgtc accacgacac cgcggtagaa 60001 gccctgcacc aggttgacct cgggcaggtg ctcgtacacc gcgaagagcg gcagcgcggc 60061 cagcagcgag ccctgcgggg cgcgggcggc ggccgtcgtc gcgaagcggt cggcctcctc 60121 gcgtgagccg tgccacttct cgcaccagaa gtgcagggcc gcgatgtgcg cgcccatgtg 60181 cgccggggcg cggtcgatga tcttcgccca gagctggtcg aactcctcgt gggagtagcc 60241 cagtccacgg gcgacggcca gctcgacgat gtacgggacg gggtcgcccg gagccagcag 60301 ggccgcctcg ccgcagaccg tacgggcctc ctccaggatg atccggaagt cgtccgtgcc 60361 cacggtgccc gtgcgccacg cctgctgcac caggaactcc gcgtgcaccg ccgccgcgcc 60421 cgcgtccttc ggggcctcgg cccgccacgt cctcagccac gccccgccgg cacccggccg 60481 ctgcgccagc tccagggagg ccgcaccggc gaacgcctgc acccgctgcc agcggatctc 60541 gctctccttg ggcgtgcccg cgagcagctg cgaggcggcc cgccagctcc ccgtgccctg 60601 gacgacgtcg agcacgtcga ggaggtcctg gtcggggccc ggcatccgga cgtccagctc 60661 ctcctggcgt gcgaagccgt acgtgtccgg gtcggcggcg tcgggcgaac cgggcgcgac 60721 ctggcggata ccgccacggc gccgcagcat gagcgggccg acgacggcga cgagcatgca 60781 cacggcgagc aggaaccaca gaatctccat gcggcccatt gtccccggac gggtaaccgg 60841 gcggcgagtg gcctgtgact gccctcccga cgaactacgc tcgggcccca tgagcgacca 60901 gcacagcttc gagacccttg cgatccacgc cggcaacacg gcggatcccc tcaccggcgc 60961 cgtggtcccg ccgatctacc aggtgtccac gtacaagcag gacggcgtcg gcggactgcg 61021 cggcggttac gagtacagcc gcagcgccaa ccccacccgc accgcactgg aggagaacct 61081 cgccgcactg gagggcggcc gccgcggact cgccttcgcg tccggcctcg ccgccgagga 61141 ctgcctcctg cgtacgctgc tgacccccgg cgaccacgtg gtcatcccga acgacgcgta 61201 cggaggcacg ttccgcctgt tcgcgaaggt cgcctcgcgc tggggcgtgg agttctcggt 61261 cgcggacacc tcggacgtga gcgcggtacg cgcggcgctc accccgcgca ccaaggcgat 61321 ctgggtggag acgccctcga acccgctgct cggcatcacc gacatcgccg ccgtcgccgg 61381 cgtggcccgg caggcgggcg tgcggctggt cgtcgacaac accttcgcca gcccctacct 61441 ccagcagccg ctctcgctcg gcgcggacgt cgtcgtgcac tccaccacca agtacatggg 61501 cggccactcg gacgtcgtgg gcggcgcgct cgtcgtcggc gacccggagc tggccgagga 61561 actggcgtac caccagaacg cgatgggcgc ggtcgccggg ccgttcgacg cgtggctggt 61621 gctgcgcggc atcaagaccc tcgcggtccg catggaccgt cacgacgcga acgccaccaa 61681 ggtcgccgac ctgctgaccc ggcacccgaa ggtcacccag gtcctctacc cgggcctgcc 61741 ggagcacccg ggccacgagg tcgccgccaa gcagatgaag gcgttcggcg ggatggtgtc 61801 gttccgcgtc gcgggcggcg aggaggcggc ggtcgaggtc tgcaaccggg cgaagctctt 61861 cacgctcggt gagtcgctcg gtggcgtgga gtcgctgatc gagcacccgg gccgcatgac 61921 gcacgcgtcc accgcgggct ccctgctgga ggtcccggcc gacctggtcc ggctgtccgt 61981 cggcatcgag aacgccgacg acctgctggc cgacctgacg caggcgctgg gctgacccgg 62041 atccgtccgg cggccgggat cggtcccggc cgccggacgg cgtgcgtagc gacgtcagac 62101 agctgccttc tcgtcctcca gcgaggcccg gatctggtca cgcagctccg ggctgtccgt 62161 gtgctcatgg accgataccg cgtgctcggc ggccgcccgg acgacctcgt cctcctcacc 62221 ggagatggtg agggtgcagt tcatgacgct cgggtaccta cggcagtcgg cgatcttccg 62281 tgtcatggcg ggcctcctcg actcgcgagt gcaggcactt ccagggtaga tccgccgggc 62341 cggacggaca ggccgggaga gcccgtcagt tctcctgggc cgactggtgc gccgactgcc 62401 gggccgccag cgagccgttg aaccgggtca gcagggcgca gaacgtgtcg cgctcctcct 62461 cggtccagcc gtcggtcacc tgggacatca gctcacgccg cgaggcgcgg acctcctcca 62521 gccgggactg gccgcgcggc gacagctgca gcacgacggc gcgcccgtcc tccgggtgcg 62581 aggtgcgctt gaccagaccg gtgtcgacga gcggcgcgac ctgccgggtc acggtcgacg 62641 agtcgatccc catgcccgcg gccagcgcct tgacgcccat ggggccttcc acgtcgagcc 62701 ggttgagcag caggtaggcc gcccggtcca tcgagttgcg gacctggccg acaccgccga 62761 ggcgggtctg ctcggcacgg cgggcgaaga cggccacctg gtgctggaga gcgtcgagca 62821 ggtggtcggt tcccggatgt ccgggggccg cgcccccgga aggagacgcg gcagtcgtca 62881 tgtcctgagg gggcatggcc ggaggctctc ttcgtgcggt gtcggatggg tgggggacag 62941 agtacgcggc cacggggcaa cgtgtaccag cgctgcacaa acctgtggac accaccgcag 63001 gccgccatga gatgcgacgg ccccgaccgc tccgagctgc aagacttgct gtcatgagct 63061 tccgtacgtc aggccccttc cctccgctga tcctcgacga cgtccgaggg gcgcagaaga 63121 tgctgtccgg ggtggccaga acgaccggga tggaaggcag ccgccacctc agctcactcg 63181 tcggcgcacc ggtccacctc aagtgcgaga acctccagcg caccgggtcg ttcaaactgc 63241 gcggcgcgta cgtgcggatc gccgggctca gccccgtcga gagggcggcg ggcgtggtgg 63301 ccgcgagtgc cggaaaccat gcgcagggtg tcgcactcgc ctcttcgctg ctcggcgtac 63361 gctccacggt cttcatgccc gtcggcgccc ccctgccgaa ggtcgcggcg acccgggagt 63421 acggcgcgga ggtccggctc cagggccatg tcgtcgacga gacgctcgcc gccgcccagg 63481 agtacgccga gcagaccggc gccgtcttca tccacccctt cgaccacccg gacatcatcg 63541 cgggccaggg caccgtcggc ctggagatcc tcgaacagtg cccggaggtc cgcacggtcg 63601 tcgtcggcat cggcgggggt ggcctggccg ccggcatcgc ggtcgcggtg aaggcgctgc 63661 gccccgacgt caaggtcgtc ggcgtccagg cggcgggagc ggccgccttc ccgccctcgc 63721 tgtccgccgg ccacccggtg gcgctggact cggtgcagac catggccgac gggatcaagg 63781 tgggccgccc cggcgacctc acgttcccgc tggtccagga gctggtcgac gaggtccgta 63841 cggtctccga ggacgagctc tccagcgcgc tgctgctctg cctggaacgc gccaagatgg 63901 tcgtcgaacc ggccggggcg agccccgtcg ccgcgctgct gagcgacccg aaggcgttcc 63961 gggggcccgt cgtcgccgtg ctgtcgggcg gcaacgtgga ccccctgctg atgcagcgca 64021 tcctgaccca cggcatggtc gccgcgggcc gctacctgag cctgcggctg cggctcaccg 64081 accggccggg ggcgctggcc gcgatgctcg ccaccctgtc cgtcgccgac gccaacgtgc 64141 tcgacatcca gcacgtgcgg accgacccac ggctcgggct caccgaggcc gaggtggaac 64201 tccacctgga gaccaagggc cccgagcact gcgaggaggt cgccgccgcg ctgcgcaccg 64261 cgggctacct ggtgcgttcc tgaggcgcgc ccccagaggt tcctcgggtc ttcccgagcg 64321 gcgggtccct tcgcgaaaac cagttgtgag tcgcgatgta tcgcgttacc gtgcatcgcc 64381 gaacactccg gtgttcccgg ccccgagggg ccgggaaccc tacgatccgc tcaggaattc 64441 acgcgaaagc aactggggga atcccgtatg ccaggcgcca tttacgccga aggcctggtg 64501 aagaccttcg gcgatgtacg agcactggac ggcgtcgacc tcgacgtacc cgaaggcacc 64561 gtcctcggcc tgctggggcc caacggcgcc ggcaagacga ccgcggtccg cgtcctgacc 64621 accctgatcc agccggacag cgggcaggct gtcgtcgcgg gcatcgacgt cctgaagaac 64681 cccgacgagg tacgacgctc gatcggcctc tccggccagt tcgcggccgt cgacgaatac 64741 ctcaccggcc gcgagaacct ccagatggtc gggcagctct accagatggg cgcacgcgac 64801 gcgaagaagc gggcggggga gctcctggag aagttcaacc tcgccgatgc cgccgaccgc 64861 accgcgaaga cgtactccgg aggcatgcgc cgccgcctcg acctggcggc ggcgctcgtc 64921 gtctccccgc cggtgatgtt catggacgag cccaccaccg ggctcgaccc gcgcaaccgg 64981 cagcagctct gggaggtcat cgaggagctc gtcgcgggcg gtacgacgct gctgctgacc 65041 acgcagtacc tggaggaggc cgaccacctg gcccacgaca tctgcgtcat cgaccacggc 65101 aaggtcatcg cccgcggcac ctccgaccag ctcaaggccc gtacgggcgg cgagcgcgtc 65161 gaggtcgtcg tgcaccggcc ggacgagatc gggccggccc gctcggtgct cgccacgtac 65221 ggcaaggggg agatcgccgt cgccgagcac acccgcaagc tgacggtccc ggtcaccggc 65281 ggggccaagc tgctcgccga ggtcatccgc gacctcgacg cccacggcgt ggagatcgac 65341 gacatcggcc tgcgccgccc caccctcgac gacgtcttca tctcgctcac cggccacgcc 65401 gccgagctgg ggaagaacgg cgagaacgca tcgaccgagg ccgcagaggg ccggaaggag 65461 gacgggcagt gaccgccgtc acggacacac cgaacctgcc gctcaagaat cgcggggcgc 65521 tcggccggtc ggtggccgac tccctcgtcg tcgcccggcg caacctgatc cgcatggcca 65581 ggatccccga gatggtgatc ttcggcctgg tgcagcccat catgttcgtg gtgctgttca 65641 cctatgtgtt cggcggatcg atcaaggtcg gcggttcact ctcgtcgacg gcctacaagg 65701 agttcctgat ggccgggatc ttcgcccaga ccgtcacctt cgccaccgcc ggcgcgggag 65761 cgggcatcgc ggacgacatg cacaaggggc tgatcgaccg cttcaggtcg ctgccgatgg 65821 cccggggcgc cgtgctcacc ggacgtacgc tcgccgacct cgtccagacc gcgctcaccc 65881 tcgtcgtcct cgccggtgtc gcgctgatca tcggctggcg gacccacgag aacatcggca 65941 aggtgctgct cggcttcctg ctgctgctcc tcctcggcta cgccttctcc tggatcggcg 66001 cgatgatcgg cctgatcgtg cgcaccccgg aggcggccac gtccggcgga ctgatctggc 66061 tcttcccgct gacgttcatc tcgaacgcct tcgtggacgc caaccagatg ccgacggtcc 66121 tgcgccacat cgccgagtgg aaccccttca gcgccaccgt gcaggcctgc cgcgagctgt 66181 tcggcaacct gccgcccggc ttcgtcaccc cggacgcctg gccgatgcag cacccgatcc 66241 tcgcctcggt gatctggtcg gtcgtgatcg tcgcggtctt ccggaccctg gcggtccgca 66301 ggtaccgctc ggccacggcc tgaccccgca cacgagggag ccccggccgc gtccgcggcc 66361 ggggctcctc tgcgcaaggg ggtacgggtc agcccgtgta gggcttcgcc gagacgatct 66421 tcaccgtggc cttcttgccg ttcggcagct cgtactccgc ggtctcgccc atccgcttgc 66481 cgttcacgcc ggtgccgagc ggggactggg gggagtaggt ctcgatgtcg gcgctcgcgt 66541 actcacggga ggcgagcagg aaggtgaccg tgtcgtcggg gtcgccgtcg aaggcgatgg 66601 tcacgaccat gccgggctcg accacgccgt cgtcggcagg tgcctcgccg accttcgcgt 66661 gctccaggag ctgggtcagc tgacggaccc ggagctccat cttgccctgc tcctccttgg 66721 ccgcgtggta cccgccgttc tcacggaggt caccctcctc ccgggccgcc gcgatcttga 66781 cggagatctc cgtgcgcgcg ggaccagaca ggtactccag ctcggccttc agctggttgt 66841 acgcctccgg cgtgagccag gtgacgttat cgctggtctg ggtcacaggg tgctcctcgt 66901 cggtgctggg aatacaaagc aacgccctac cccaagcatg cgctgccacg ggtgggcgaa 66961 acaacgagcc taacaattcc gcgcgaaaag ggggagaagg taaaacgtca cacgcacatc 67021 ggcgcaggtc agccccgaat cgtgggggtg aggtcggcgc gcgccccggc gcgcggccgg 67081 ccgtgggcgt cgcggtgcgc tcagccgccc gaggcgcagc ccttgagttc caccgccgtg 67141 gccctggaag tggtgcgcag ggtgacgacc tcgtcgatcc gctcggaccg ctcgtcgaac 67201 cggaagtcgg cccggccgac ctccccgccg tcctcgctca gggcgcggag cgtgcagtgc 67261 ccgtcggcgt cccggtcctt gcggacctcc aggtgggcct cggcgcggct gtcggagacg 67321 atcctcgact tgatgagctc ggcgctgacg tccgtaccgg cgacgtacgc gtatccgaac 67381 cagccgatca cggcgaggaa ggcgacaccc agaaccgagc cgatgatctt cagcttgcgg 67441 tccgcgcgtt cgtcctgcga ccggccgtag cgcccctcgg gcaaggcctc gcgcaccgct 67501 gccatgatcg ttcctcccgt accggggatc gaggaatttt ccaccccccg gttcagtcac 67561 tatagaagcc gaccactgcg accgatcact gaggaccgag tcttgaccga gcagctgaga 67621 ctgatggccg tccacgccca ccccgacgac gagtcgagca agggcgcggc caccatggcc 67681 aagtacgtgt ccgagggggt ggacgtcctg gtcgtcacct gcacaggggg cgaacgggga 67741 tccatcctca acccgaagct ccaaggggac gcgtacatcg aggcgaacat ccacgaggtg 67801 cgcaagaagg agatggacga ggcccgggag atcctgggcg tcaagcagga gtggctcggc 67861 ttcgtcgact cgggtctgcc cgagggcgat ccgctgccgc cgctgcccga gggctgcttc 67921 gccctggagg acgacgagac ggcggcgggg cgcctcgtcg cgaagatccg cgcgttccgg 67981 ccgcaggtga tcaccaccta cgacgagaac ggcggatacc cgcaccccga ccacatcaag 68041 acccacacga tctcgatgat cgcgttcgag ggggccgggg acaccgagag gttccccgag 68101 gcggagttcg gcccggcctg gcagccgcag aagctctact acaaccaggg cttcaacaag 68161 ccgcgcacgg tcgccctgca cgaggcgctg ctcgcccgtg gcctggagtc cccgtacggc 68221 gactggctgg agcgctggaa gcagttcgag cgcgccgagc gcacgctgac cacgcacatc 68281 ccgtgcgacg acttcttcga gatccgtgac aaggcgctga tcgcgcacgc cacgcagatc 68341 gatccggacg gcggctggtt ccgggtgccg atggacgtcc agcgggaggt ctggccgacc 68401 gaggagtacg agctcgccaa gtctctggtc gatacctccc tccccgagag cgacctcttc 68461 gcgggcatcc gcgacaatgc ctgatatgta cgcgacccag gcactgacgc agctcgttcc 68521 gctcgccgcc gatgagctcg acaagaacaa ggtgaccccc ggcgtcctcg gcttcctcgt 68581 cttcgcggca ctcgccgtcg ggacatggct cctgatgaag tcgatgaacc gccacatggg 68641 caaggtcgac ttcgaggagg cccccgaccc ggcggcccgg ccgggtgaca ccgacggaga 68701 gccggcggag gcgtcctccg gcgccgggac gaaggcggcc ggcacgaagg caaccgcctc 68761 gggcaagggc tgacacggcg gggccacccc cttccccgta cggggcgggg gtggcccgcg 68821 ccgtccctca ggcccgccgg tgcgcgtcgt tcagatggcg cagcacggcc gcgacccggc 68881 ggtccgtgcc gtcggcgggc gccaggtcga gcttggcgaa gatgctccgg atgtgcttgt 68941 ggacggcgcc gtccgtcacc acgagccgct cggcgatcgc cgcgttgccc aggccctccg 69001 ccatcagggc caggacctcc cgttcgcgcg ggctcagccg gtccagacgg gtgtcggggc 69061 gggtccgcgc gaagagctgc gcgaccacct cggggtcgat ggccgtgccg ccgtccgcga 69121 cccgctccag agccgtgagg aactcctcga cccggccgac ccgctccttg agcagatacc 69181 cgagccgggc gctgccgtcg gcgaggaggt cggtggcgaa ggcctgctcg acgtaggcgg 69241 acagcacgag gaccgcaagc cccggctgac ggcgccgcgc ctccacggcc gccctgatcc 69301 cctcgtcggt gtgcgtcgga ggcatccgta cgtcgacgat cgcgaggtcc ggccggtgct 69361 cgtccaccgc cgccaggaag acgtccgggg tacccgcggt cgccacgacg tcgaggccct 69421 ccgcgcgcag cagcagcgcg agcccctccc tcagcagcgg gtcgtcctcc gcgatcacga 69481 tccgcatggc agtccggcct ccagtgtcgt gggcccgccc ggtgggctgg ccagggtgag 69541 tacgccgtcc agcgcctcga cgcgcttacg gatgccggcc aggccggacc cgccgtgctc 69601 gtccgctccg ccgcggccgt cgtcggtgac ccggagccac agccgtccgt cgcggtggcg 69661 gaccgtgacc gacgcggccc gtgccccgct gtgccgggcg acgttggtga gcgcctccgc 69721 caccacgaag taggcggtcg cctcgaccga cgcggcgaac cgcccctcca cgtccgcgtc 69781 gacccggcag ggcaccgggc agctgcccgc cagccccgag agcgcgtccg tcaggctccg 69841 gtcggccagc accggcggca ggatgccccg tacgaccgcg cgcagttccg cgagtgcctg 69901 ctcggcggcg tcctgggccc gttccagcag ggcgtcggcg tcggcggagc cccgggacac 69961 cgcccggcgg gacgcgccca gcagcaccgt caccgcgacc agccggttct gggtgccgtc 70021 gtgcagggcc cgttcgatgc gccgcagctc ggtggcgtgc gcgtccaggg ccgcggcgcg 70081 ggtcgcggtg agctcggtga cgcgcgtcac gaggtcggtg ccgggaggag gggtgagcag 70141 ccgccgcccc ggccacgcct ggagccgcgc catgccgggt gcgacggcca gggtgagggc 70201 gaaccatccg atccccagca gactgaccgc gaaggccccc ggccagtcct gcacggtcca 70261 caggccgagg gacggggtgg cctccgaggg cggcacgaac gaccaccaca gcgggaacgc 70321 ggcatccgtc gccgaggtga ggggcagcgt cagcccgacc aggcccagcg ccgtcccgag 70381 gacggcgtgc gaggccaccc agcccacctc gcgccgggtg gccgggtcgg cggcggcctc 70441 ccgcagccgg gtcggtgcgg gccccggccc gatgacctcc ggcccccacc gggacagccg 70501 cacgcgttcg cgtccggcga cggcgcgcag cgccctcagg gtgccgggca ccaggaacag 70561 gccgaccccg acgaggcagg cggcggcggt gaacaccagc cacagcagcg tgatcagggc 70621 gaggatcgcc gtaccgatgc cgccgacgag atgctcgaag gcgtcgagag cggtccgggc 70681 gcgggcgaac acgtcccagg ggcgggccgg ttcctgtgcg gtcgccggcg gggcgtcgtg 70741 cgcgggcatc tccacctcct ggtgccgcgc cactatggca tctcccgccg ggtgcgcgac 70801 gggcagggga cgacaggtac agcctgctgt accccggccc tccacctggc gggatcgtcg 70861 cccccgcgcc gcctccgtag cgtcctttcc gtgcccaact ccccctcgga caaggagaag 70921 acgatggctg attccacccg gcggtccgca cgtcccgtgc tctggctgct gctcctgctc 70981 tgcgccgtct gcaacgcggt cacctcgatg atgggcggga tcgccacggc cgtctccgtc 71041 gccgccgggc tcgccgccct ggcctgcggg atcgccctcg tcgcggacca ccgccgcgcc 71101 cgctccacgg agaggaacgc ccgatgagcg ccgcgaccca gctcggcgcg ggctcccctc 71161 cggcgcccag cacgcccgag ccgcgcggcg gctggcgggc cggcatgcgc cgctaccccc 71221 tgacctggtt cttctcgctg gccttcgtgc tgagctgggt gggctgggtg ccgtacatcc 71281 tgtccgggaa cggccagggc gtcctggact tcaccttccc cgggggcgag gccgccggcc 71341 agctgctggg ggtcctcccc ggcgcctacc tgggcccgat cctctccgcg ttcatcgtca 71401 ccgccgtcgc cgacggacgc cccggactcc gcgcctgggc agggcggatg accaagtggc 71461 gggtcggctg gcgctggtgg gccgcgatca tcgtcaccgt gccgctcgtc ctcgtcctca 71521 cgctgtacgc cctgggcggc gagagcccgg tcatgccgag cgccgtggtg ctggtcgcct 71581 tcctgcccgg cctggccctc cagatggtca ccaccggtgt cgccgaggag ccgggctggc 71641 gcgacttcgc gatgccccgg ctgcaggaca ggttcggccc cgtccgcggc acgctggtcc 71701 tcggtccgct gtggggcgcc tggcacctgc cgctgtacct cagcgactgg ggcggcccgc 71761 acgtcctgtg gtggacaccc gtggagttca tcgccaccac gatcgccttc agcttcgtga 71821 tgacctgggt cttcaaccac acccggcagg ccctgctgct ggccatgctg ctgcacacca 71881 gcgtcaacaa ctacttctcg gtcgccttca ccggcatgtt cccctcgctg gacccggcgt 71941 acgcggggca cgccttcctc gtgagctcca cggccgctgc cgccgtgctg ctcctcgcca 72001 cccgcggccg gctcggcctg ccccgcgcat agggccggtg cctacggacg tacgcccacg 72061 gcgacgccca tcacctcgcg ggcgtgccgg gacggcgtca ggccgagacg ccaggcctgc 72121 cagccgtcgt ccaggtccac cccgcggttc aggaccaccc ggaaggcctc ggcgcagtcc 72181 tccagttggg cgtcacgcag cgggtgggcg gcctccacca gatcggccag ctcctgctgc 72241 gccaccgccg tgcccacctc gctgccgccc ggtgaggcgt acggcaacag ggtgcaccgc 72301 aggaacgccg cccagtcgcc gccccgggca tcgccgtacg aggcgaacag ggtgatcgcc 72361 tcgccgcaga gctccagcgc ctgggcggcg cggttgttcc cgccgtcgac cagggccagt 72421 tccaggcagg tccaggcctc gccgtggggc accccgatcc gccgaaagtc ggcccgggcg 72481 tccaccagga gctgccgggc gaagccggag ttgcgcaggt tgccggtctg cgcggcccgc 72541 tggtcacggg tgacgcggcc cgagtggtgg cgg //