LOCUS       NZ_RDBM01000022        26575 bp    DNA     linear   CON 01-JAN-2025
DEFINITION  Streptomyces sp. gb1(2016) Scaffold_22, whole genome shotgun
            sequence.
ACCESSION   NZ_RDBM01000022
VERSION     NZ_RDBM01000022.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. gb1(2016)
  ORGANISM  Streptomyces sp. gb1(2016)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 253699)
  AUTHORS   Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K.,
            Campbell,A.N. and Buckley,D.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University,
            306 Tower Road, Ithaca, NY 14850, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: A5+MeDuSa v. JUNE-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008042065.1-RS_2025_01_01
            Annotation Date                   :: 01/01/2025 02:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,414
            CDSs (total)                      :: 7,333
            Genes (coding)                    :: 6,887
            CDSs (with protein)               :: 6,887
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 447
            CDSs (without protein)            :: 446
            Pseudo Genes (ambiguous residues) :: 0 of 447
            Pseudo Genes (frameshifted)       :: 94 of 447
            Pseudo Genes (incomplete)         :: 395 of 447
            Pseudo Genes (internal stop)      :: 7 of 447
            Pseudo Genes (multiple problems)  :: 48 of 447
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:17:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 26909
            Orig. end                         :: 53484
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RDBM01000022.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..26575
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="terpene"
                     /region_number="1"
                     /rules="(PT_phytoene_like or phytoene_synt or Lycopene_cycl
                     or Lycopene_cycl_fung or T1TS or T1TS_KS or T2TS or TS_UbiA
                     or TS_Pyr4)"
                     /tool="antismash"
     cand_cluster    1..26575
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /kind="single"
                     /product="terpene"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..26575
                     /aStool="rule-based-clusters"
                     /category="terpene"
                     /contig_edge="False"
                     /core_location="[10000:16575](-)"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..16575)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(PT_phytoene_like or phytoene_synt or
                     Lycopene_cycl or Lycopene_cycl_fung or T1TS or T1TS_KS or
                     T2TS or TS_UbiA or TS_Pyr4)"
                     /neighbourhood="10000"
                     /product="terpene"
                     /protocluster_number="1"
     misc_feature    complement(55..70)
                     /note="TFBS match to RutR, Regulator of the pyrimidine and
                     purine metabolism, confidence: weak, score: 19.63"
                     /tool="antismash"
     misc_feature    69..82
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 14.12"
                     /tool="antismash"
     misc_feature    complement(168..182)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 18.8"
                     /tool="antismash"
     gene            complement(171..1082)
                     /locus_tag="EAO74_RS05760"
                     /old_locus_tag="EAO74_05770"
     CDS             complement(171..1082)
                     /EC_number="3.4.-.-"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152774.1"
                     /locus_tag="EAO74_RS05760"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05770"
                     /product="LysM peptidoglycan-binding domain-containing M23
                     family metallopeptidase"
                     /protein_id="WP_147982894.1"
                     /transl_table=11
                     /translation="MPAKGKHRRTKTGPISRGFLAAGTGCAVLALPLIGATGAHAAEQS
                     APAAAAHSASASAPAAKSAPKTYSVVSGDYLAKIAAEKKVKGGWQKLYQDNRDVVGENP
                     SLILPGMKLTLGAKASGSAEAAPSTSAPSAAKKAAPAEKTAAPAEKTAAPAAETADSGA
                     SESTGSGWAAPVENPNVTTQYRASGASWSSGYHTGSDFQAASGTSVRSIGPGTVVSAGW
                     SGSYGNEVVIQHEDGMYSQYAHLSSLEVSAGQTVTGGQQIGLSGTTGNSTGPHLHFEVR
                     TGPSYGSDVDPIAYLRSHGVSI"
     regulatory      complement(1088..1246)
                     /bound_moiety="cyclic di-AMP"
                     /db_xref="RFAM:RF00379"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:14.4:RF00379"
                     /inference="COORDINATES: profile:INFERNAL:1.1.5"
                     /note="cyclic di-AMP (ydaO/yuaA leader) riboswitch senses
                     the signaling molecule cyclic di-AMP; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /regulatory_class="riboswitch"
     misc_feature    1256..1270
                     /note="TFBS match to IolR, Regulator of the inositol
                     catabolism, confidence: strong, score: 20.54"
                     /tool="antismash"
     misc_feature    complement(1308..1323)
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 21.71"
                     /tool="antismash"
     misc_feature    complement(1497..1511)
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 15.37"
                     /tool="antismash"
     gene            1662..2486
                     /locus_tag="EAO74_RS05765"
                     /old_locus_tag="EAO74_05775"
     CDS             1662..2486
                     /EC_number="3.1.3.48"
                     /GO_function="GO:0004721 - phosphoprotein phosphatase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004725 - protein tyrosine phosphatase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006470 - protein dephosphorylation
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152775.1"
                     /locus_tag="EAO74_RS05765"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05775"
                     /product="tyrosine-protein phosphatase"
                     /protein_id="WP_124275925.1"
                     /transl_table=11
                     /translation="MTQLPEVPPVGPEPTDVDLTGVRNFRDVGGLPTVDGSAVRYGRLY
                     RSGHLAHATESDAAFLAGLGLHTIFDFRNAADHKLDGLDVELPGVRNVSIPLSDPADGA
                     EFWRLVRDGNIQQLRSILADGKGTDRMVASYRSIIKDRTGEHSRVLHALAEDSVPALMH
                     CAAGKDRAGLSVAVSLLAVGVPKEAIEADYLKSNDAHRRYKVRRSDTSAVGMSDEVMEL
                     LNPLFGAHAEYLAAAFDTIDEIWGGTDRYLREGLKISDETRAKLRERLVEGA"
     gene            complement(2498..2671)
                     /locus_tag="EAO74_RS37355"
     CDS             complement(2498..2671)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152776.1"
                     /locus_tag="EAO74_RS37355"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="DUF6126 family protein"
                     /protein_id="WP_164493677.1"
                     /transl_table=11
                     /translation="MSDSEHYDPLTPRRPRSADTQERRMPRGVVIRLFAYLVAGHVIAG
                     FLYLLFTVAGKG"
     gene            complement(2866..3486)
                     /locus_tag="EAO74_RS05770"
                     /old_locus_tag="EAO74_05780"
     CDS             complement(2866..3486)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152777.1"
                     /locus_tag="EAO74_RS05770"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05780"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_147982895.1"
                     /transl_table=11
                     /translation="MNPPDGGVADELPGVAPRLRDLRRNRGLTLEGAAARAGLSPAHLS
                     RLETGRRQPSLPMLLGLARVYGTTVSELLGEMPPERDAIVRGGAPEGAPRGTEAGGWLY
                     RQAGAPGRAMQALHVRVPHGAESDLVRVHPGEEWLYVLDGRLRVVLGETVHDLGPGDSA
                     HFDSLTPHRIAAPDTGGARLLFVHTLLQSPAAELCLGGGTHRL"
     misc_feature    3450..3464
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: strong, score: 19.35"
                     /tool="antismash"
     gene            complement(3553..4947)
                     /locus_tag="EAO74_RS05775"
                     /old_locus_tag="EAO74_05785"
     CDS             complement(3553..4947)
                     /NRPS_PKS="Domain: Aminotran_3 (44-366). E-value: 3.1e-88.
                     Score: 288.0. Matches aSDomain:
                     nrpspksdomains_EAO74_RS05775_Aminotran_3.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1013: aminotransferase class-III"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552430.1"
                     /locus_tag="EAO74_RS05775"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05785"
                     /product="aspartate aminotransferase family protein"
                     /protein_id="WP_124275923.1"
                     /sec_met_domain="Aminotran_3 (E-value: 1.9e-87, bitscore:
                     287.4, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDERPGFDLGRLLAERGAERYELHTRHLNHQLPRMLHTLGFDKV
                     YERAEGAHFWDEEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVLDASLADLTRFDCQPL
                     PGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRILYCDHAFHGLTTGSL
                     SVNGEKGFRDGFAPLLPDTAIPLGDLDALRRELKRGDVAGLVVEPIQGKGVHASPPGFL
                     REAQELLHRHKAVLIADEVQTGLGRTGDFYAYQHEEGVEPDLLCVAKALSGGYVPVGAT
                     LGKDWIFKRVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEQEEIVANARRTGDLLRE
                     RLAALVGRYELLHEVRGRGLMIGIEFGRPSSLKLRSRWTMLQAARKGLFAQMVVVPLLQ
                     KHRILTQVSGDHLEVIKLIPPLVIGEPEVDRFVTAFTAVMDDAHSGGGLMWDFGRTLVK
                     QAVANR"
     aSDomain        complement(3850..4815)
                     /aSDomain="Aminotran_3"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EAO74_RS05775_Aminotran_3.1"
                     /evalue="3.10E-88"
                     /label="EAO74_RS05775_Aminotran_3.1"
                     /locus_tag="EAO74_RS05775"
                     /protein_end="366"
                     /protein_start="44"
                     /score="288.0"
                     /tool="antismash"
                     /translation="VYERAEGAHFWDEEGNDYLDMLAGFGVMGLGRHHPVVRKALHDVL
                     DASLADLTRFDCQPLPGLLAERLLAHSPHLDRVFFGNSGTEAVETALKFARYATGKPRI
                     LYCDHAFHGLTTGSLSVNGEKGFRDGFAPLLPDTAIPLGDLDALRRELKRGDVAGLVVE
                     PIQGKGVHASPPGFLREAQELLHRHKAVLIADEVQTGLGRTGDFYAYQHEEGVEPDLLC
                     VAKALSGGYVPVGATLGKDWIFKRVYSSMDRVLVHSASFGSNAQAMAAGLAVLSVMEQE
                     EIVANARRTGDLLRERLAALVGRYELLHEVRGRGLMIGIEF"
     gene            complement(4944..6854)
                     /gene="dxs"
                     /locus_tag="EAO74_RS05780"
                     /old_locus_tag="EAO74_05790"
     CDS             complement(4944..6854)
                     /EC_number="2.2.1.7"
                     /GO_component="GO:0005737 - cytoplasm [Evidence IEA]"
                     /GO_function="GO:0008661 - 1-deoxy-D-xylulose-5-phosphate
                     synthase activity [Evidence IEA]"
                     /GO_process="GO:0008615 - pyridoxine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009228 - thiamine biosynthetic process
                     [Evidence IEA]"
                     /GO_process="GO:0009240 - isopentenyl diphosphate
                     biosynthetic process [Evidence IEA]"
                     /codon_start=1
                     /gene="dxs"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DXP_synthase_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1110: 1-deoxy-D-xylulose-5-phosphate synthase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552431.1"
                     /locus_tag="EAO74_RS05780"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05790"
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="WP_147982896.1"
                     /sec_met_domain="DXP_synthase_N (E-value: 1e-111, bitscore:
                     366.4, seeds: 174, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.7e-07, bitscore:
                     25.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTMLESIKGPQDLKALSRPELGELAEEIRTFLIRAVARTGGHLGP
                     NLGVVELTIALHRVFDSPVDRILWDTGHQSYVHKLLTGRQDFSKLRSKGGLSGYPSREE
                     SEHDVIENSHASTVLGWADGLAKADEVRERGRHVVAVIGDGALTGGMAWEALNNIAAAR
                     DRPLIIVVNDNERSYAPTIGGLANHLATLRTTDGYERFLSWGKGVLQQTPVIGPPLYGS
                     LHGAKKGFKDTFAPQGMFEDLGLKYVGPVDGHDTAAVEAALQRAKRFHGPVLVHCITEK
                     GRGFPPALADDADRFHTVGRMDPLTCEPLVLPAAPSWTSVFGDEIAEIGAVRPDVVAIT
                     AAMLHPVGLTRFAEEFPDRIWDVGIAEQHAAVSAAGLATGGLHPVVAVYATFLNRAFDQ
                     LLMDVALHGCGVTFVLDRAGVTGPDGPSHNGMWDMSLLQVVPGLRIAAPRDADRLREEL
                     REAVDVDDAPTVIRFPKESVGEPVMAVGRIGGMDVLHRAPDADVLLVAVGVLAPVCLQA
                     ADLLAGSGIRCTVVDPRWVKPVDAQLPALAAQHRLVAVVEDNSRSGGVGWAVGQALRDA
                     GADVPLRTYGIPEQFLAHAGRGEVLAEIGLTPVEIAGSISAALERRTAAGERNMPKENG
                     A"
     gene            complement(6888..>7253)
                     /locus_tag="EAO74_RS05785"
                     /old_locus_tag="EAO74_05795"
     CDS             complement(6888..>7253)
                     /EC_number="1.17.7.3"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0016114 - terpenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019763637.1"
                     /locus_tag="EAO74_RS05785"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05795"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_187281728.1"
                     /transl_table=11
                     /translation="LQILEALNLKQRRLEIVSCPSCGRAQVDVYKLADQVSAGLEGMEV
                     PLRVAVMGCVVNGPGEAREADLGVASGNGKGQIFVKGEVIKTVPESKIVETLIEEAMKI
                     ARVWRRRGHPAGSPQSP"
     assembly_gap    7254..7353
                     /estimated_length=100
                     /gap_type="within scaffold"
                     /linkage_evidence="paired-ends"
     gene            complement(<7354..8306)
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /locus_tag="EAO74_RS05790"
                     /old_locus_tag="EAO74_05800"
     CDS             complement(<7354..8306)
                     /EC_number="1.17.7.1"
                     /GO_function="GO:0046429 - 4-hydroxy-3-methylbut-2-en-1-yl
                     diphosphate synthase activity (ferredoxin) [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="ispG"
                     /gene_synonym="gcpE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018534474.1"
                     /locus_tag="EAO74_RS05790"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05800"
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="WP_147983014.1"
                     /transl_table=11
                     /translation="MSPGEPVVLGLPGLPARPLAVRRPSRRIQVGSVAVGGDAPVSVQS
                     MTTTRTSDIGATLQQIAELTASGCQIVRVACPTQDDADALATIARKSQIPVIADIHFQP
                     KYVFAAIDAGCAAVRVNPGNIKQFDDKVKEIAKAAGEAGTPIRIGVNAGSLDARLLKKY
                     GKATPEALVESALWEASLFEEHGFRDIKISVKHNDPVVMVNAYRQLAAQSDYPLHLGVT
                     EAGPAFQGTIKSAVAFGALLSEGIGDTIRVSLSAPPAEEVKVGLQILEALNLKQRRLEI
                     VSCPSCGRAQVDVYKLADQVSAGLEGMEVPLRVAVMG"
     gene            complement(8311..9330)
                     /gene="hpnH"
                     /locus_tag="EAO74_RS05795"
                     /old_locus_tag="EAO74_05805"
     CDS             complement(8311..9330)
                     /GO_function="GO:0003824 - catalytic activity [Evidence
                     IEA]"
                     /GO_function="GO:0051536 - iron-sulfur cluster binding
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) QueE"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006128938.1"
                     /locus_tag="EAO74_RS05795"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05805"
                     /product="adenosyl-hopene transferase HpnH"
                     /protein_id="WP_099177424.1"
                     /sec_met_domain="PF04055 (E-value: 1.5e-18, bitscore: 61.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="QueE (E-value: 6.4e-10, bitscore: 32.7,
                     seeds: 32, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAMPLRQSIKVATYLFEQKLRKREKFPLIVELEPLFACNLACEGC
                     GKIQHPAGVLKQRMPVAQAVGAVLESGAPMVSIAGGEPLMHPQIDEIVRQLVAKKKYVF
                     LCTNAMLMRKKLDKFTPSPYFAFAVHIDGLRERHDESVAKEGVFDEAVEAMKEAKRRGF
                     RVTTNSTFFNTDTPQTVIEVLNFLNDEMKVDEMMISPAYAYEKAPDQEHFLGVEQTREL
                     FKKSFAGGNRSRWRLNHSPLFLDFLEGKADFPCTAWAIPNYSLFGWQRPCYLMSDGYVP
                     TYRELIEDTDWDKYGRGKDPRCANCMAHCGYEPTAVLATMGSLKESLRAARETIGGNR"
     gene            complement(9337..9996)
                     /locus_tag="EAO74_RS05800"
                     /old_locus_tag="EAO74_05810"
     CDS             complement(9337..9996)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049660.1"
                     /locus_tag="EAO74_RS05800"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05810"
                     /product="1-hydroxy-2-methyl-2-butenyl 4-diphosphate
                     reductase"
                     /protein_id="WP_147982897.1"
                     /transl_table=11
                     /translation="MGGPQEPPGPTTPLLIACALGIERFALRTGRSGGVPGPGPVSIIR
                     SGMGPRAAENAVRLALGQDGAGGTAVIASGFCAGLEPGMHPGDLVVAEETRDSGGTTAC
                     TGTGLLVDALVRAVPGRTVHTGPLNGSGHVVRGPERAGLRATGAIAVDMESAATLRTAV
                     RXGPRPVAAVRVVVDAPEHELVRIGTVRGGISAFRVLRAVLPAFHEWHRSLLLPRR"
     gene            complement(10001..12007)
                     /gene="shc"
                     /locus_tag="EAO74_RS05805"
                     /old_locus_tag="EAO74_05815"
     CDS             complement(10001..12007)
                     /EC_number="5.4.99.17"
                     /GO_function="GO:0016866 - intramolecular transferase
                     activity [Evidence IEA]"
                     /GO_function="GO:0051007 - squalene-hopene cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0019746 - hopanoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="shc"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: T2TS"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152781.1"
                     /locus_tag="EAO74_RS05805"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05815"
                     /product="squalene--hopene cyclase"
                     /protein_id="WP_147982898.1"
                     /sec_met_domain="T2TS (E-value: 6.4e-151, bitscore: 497.4,
                     seeds: 58, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTATTDGSTGAANLRAVPASDPTEPTIAPDDISAVARRAAERSVE
                     HLLGRQDEQGWWKGDLATNVTMDAEDLLLRQFLGIQDPDTLKAAARFIRGEQMGDGTWN
                     TFYEGPPDLSATIEAYVALRLAGDRPDDPHMRRAAGWVREQGGIAESRVFTRIWLALFG
                     WWKWDDLPELPPELMFFPKWVPLNIYDFGCWARQTIVPLTIVSAKRPVRPAPFALDELH
                     ADPACPNPPKPAAPAASWDGVFQRLDKALHLYHKVAPRRLRRSAMNAAARWIIERQEND
                     GCWGGIQPPAVYSVIALHLLGYDLDHPVMRAGLESLDRFTVWREDGARMVEACQSPVWD
                     TCLATIALADAGVSPDHPALVKAADWMLAEEIVRPGDWSVRKPELAPGGWAFEFHNDNY
                     PDIDDTAEVVLALRRVSHPDPARVEAAIERGVRWNLGMQSRNGAWGAFDADNTSPFPNR
                     LPFCDFGEVIDPPSADVTGHVVEMLAVEGRAQDPRTRRGIEWLLAEQEATGAWFGRWGV
                     NYIYGTGSVVPALIAAGLPAAHPSVRRAVDWLTSVQNDDGGWGEDLRSYREEKWIGHGA
                     STASQTAWALLALLAAGERETQSVERGVAWLANTQQADGSWDEPHFTGTGFPWDFSINY
                     HLYRQVFPLTALGRYVYGDPFATAAGADTGKGA"
     gene            complement(12112..13215)
                     /locus_tag="EAO74_RS05810"
                     /old_locus_tag="EAO74_05820"
     CDS             complement(12112..13215)
                     /GO_process="GO:0008299 - isoprenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_FPPS_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1182: Polyprenyl synthetase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964849.1"
                     /locus_tag="EAO74_RS05810"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05820"
                     /product="polyprenyl synthetase family protein"
                     /protein_id="WP_187281729.1"
                     /sec_met_domain="PT_FPPS_like (E-value: 3.3e-60, bitscore:
                     197.5, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSTTGTRGESVTPANPAYDTVVDTTDVTALLERGRALSAPVLRA
                     AVDRLAPPMDTVAAYHFGWIDAQGRPADGDGGKAVRPALALLSAEAAGAPAEAGIPGAV
                     AVELVHNFSLLHDDLMDGDEQRRHRDTVWKVHGPAQAILVGDALFALANEVLLELGTVE
                     AGRAARRLTTASRKLIDGQAQDISYEHRERVTVEECLEMEGNKTGALLACAVSIGAVLG
                     GADDRTADVLEAYGYHLGLAFQAVDDLLGIWGDPESTGKQTWSDLRQRKKSLPVVAALA
                     AGGPASERLGELLAADAKSSDFDSFSEEEFAARAALIEEAGGREWTAQEARRQHTVAIE
                     ALHGVDMPERVRAQLTELADFVVVRKR"
     gene            complement(13212..14600)
                     /gene="hpnE"
                     /locus_tag="EAO74_RS05815"
                     /old_locus_tag="EAO74_05825"
     CDS             complement(13212..14600)
                     /EC_number="1.17.8.1"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnE"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1222: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579669.1"
                     /locus_tag="EAO74_RS05815"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05825"
                     /product="hydroxysqualene dehydroxylase HpnE"
                     /protein_id="WP_147982899.1"
                     /transl_table=11
                     /translation="MTGRNPRSSRALVVGGGLAGVTSALRLADAGLDVTLLEGRPRLGG
                     LAFSFRRGDLSVDNGQHVYLRCCTGYRWFLDRIEGAHLAPLQDRLDVPVLDVGRPAGPR
                     LGRLRRTGLPVPLHLAGGLAAYPHLSLAEKAGVARAALALGRLDPADPALDGVDFATWL
                     GRQGQSDRTIEALWDLVGVATLNATAPHASMGLAAKVFKTGLLSEPGAADIGWAAVPLG
                     DLHDTLARKALESAGVEIHVRTRAASLTRAEDGRWTVGTDGEGFEADTVVLAVPQGETH
                     RLLPDGALDDPGRLLELTDSPILNVHVVYDRKVLRRPFFAAIGSPVQWVFDRTESSGLQ
                     GAGQYVAVSQSAAQDEIDLPVAELRKRYLPELERLLPAARGAGIRDFFVTRERTATFAP
                     APGVGRLRPGARTRAPGLLLAGAWTATGWPATMEGAVRSGFSAADAALQALGRPHEHPL
                     QEAA"
     gene            complement(14689..15609)
                     /gene="hpnD"
                     /locus_tag="EAO74_RS05820"
                     /old_locus_tag="EAO74_05830"
     CDS             complement(14689..15609)
                     /EC_number="2.5.1.103"
                     /GO_function="GO:0016767 - geranylgeranyl-diphosphate
                     geranylgeranyltransferase activity [Evidence IEA]"
                     /GO_process="GO:0016117 - carotenoid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152784.1"
                     /locus_tag="EAO74_RS05820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05830"
                     /product="presqualene diphosphate synthase HpnD"
                     /protein_id="WP_187281730.1"
                     /sec_met_domain="phytoene_synt (E-value: 6.4e-59, bitscore:
                     193.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 3.7e-71,
                     bitscore: 233.7, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSAPVQAAYSYCEAVTGQQARNFAYGIRLLPYEKRQAMSALYAFS
                     RRVDDIGDGELDPETKHTRLEETRGLLVRIRDNAVDEDDTDPVAVALADAAHRFPLPLG
                     GLDELIDGVLMDVRGATYETWADLKTYCRCVAGAIGRLSLGVFGTETGAPGAERAAEYA
                     DTLGLALQLTNILRDVREDAGNGRTYLPADDLAKFGCSAGFHRATPPPGSDFAGLVHFE
                     VRRARALFAEGYRLLPMLDRRSGACVAAMAGIYRRLLDRIERDPEAVLRGRVSLPGHEK
                     AYVAVRGLSGLDARYISRRTARGRV"
     gene            complement(15639..16575)
                     /gene="hpnC"
                     /locus_tag="EAO74_RS05825"
                     /old_locus_tag="EAO74_05835"
                     /pseudo=""
     CDS             complement(15639..16575)
                     /GO_function="GO:0004311 - farnesyltranstransferase
                     activity [Evidence IEA]"
                     /codon_start=1
                     /gene="hpnC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: PT_phytoene_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     terpene: phytoene_synt"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018552438.1"
                     /locus_tag="EAO74_RS05825"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05835"
                     /product="squalene synthase HpnC"
                     /pseudo=""
                     /sec_met_domain="phytoene_synt (E-value: 1.6e-06, bitscore:
                     21.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PT_phytoene_like (E-value: 6e-08,
                     bitscore: 26.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRTRQAPADAAATLDKAADENFPVAPFFLPRAWRDDLMAVYGFA
                     RLVDDIGDGDLAPGGADARSLGLDPGQEDDRLAALDALEADLHRVFAPSGDGPRHPLMR
                     ALRPPDACPAPHRAALRAHPRTLPRARRGQPAGPEDPPLRDLRGPARLLRALRQPRRPP
                     RPADHRHREPRTHPPLRRRLHRPADRRTPPGRRRGPRPRPDLSARRRHGPLPHR"
     gene            complement(16994..17779)
                     /locus_tag="EAO74_RS05830"
                     /old_locus_tag="EAO74_05840"
     CDS             complement(16994..17779)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964853.1"
                     /locus_tag="EAO74_RS05830"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05840"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_129266722.1"
                     /transl_table=11
                     /translation="MAEESSQGHIPTVIADDVHIVYRVNGTGGGKGSATAALSRIMRRG
                     KGEPRGVRKVHAVRGVSFTAYRGQAIGLIGTNGSGKSTLLRAIAGLLPTEHGKVYTDGQ
                     PSLLGVNAALMSDLTGERNVVLGGLAMGMSREEIRTRYQDIVDFSGINEKGDFITLPMR
                     TYSSGMAARLRFSIAAAKNHDVLMIDEALATGDRKFRVRSEERIRELRKEAGTVFLVSH
                     NNKTISDTCDRVLWLEKGELLMDGPTDEVLKAYERETGK"
     gene            complement(17772..18701)
                     /locus_tag="EAO74_RS05835"
                     /old_locus_tag="EAO74_05845"
     CDS             complement(17772..18701)
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964854.1"
                     /locus_tag="EAO74_RS05835"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05845"
                     /product="ABC transporter permease"
                     /protein_id="WP_124275915.1"
                     /transl_table=11
                     /translation="MSDTTHDGGIALSSPPSADEGLSASQLAAKYGLTVSGARPGLFAY
                     IRQLWGRRHFILAFSRAKLTAQYSQAKLGQLWQVATPLLNALVYFLIFGLILGTNRGMS
                     QEVFIPFLVTGVFVFTFTQSSVMAGVRSISGNIGLVRALHFPRASLPVSFSLQQLQQLL
                     YSMIVLLAVAVGFGSYPSLSWLLIIPALAMQFLFNTGLALVMARLGSKTPDLAQLMPFV
                     MRTWMYGSGVMFSIPVMLEGKPQWIADVLQYNPAAIYMDLVRFALIDGYGSENLPQHVW
                     AVGLAWALVVGVVGFVYFWKAEERYGRG"
     gene            complement(18810..19682)
                     /locus_tag="EAO74_RS05840"
                     /old_locus_tag="EAO74_05850"
     CDS             complement(18810..19682)
                     /EC_number="2.4.-.-"
                     /GO_function="GO:0016757 - glycosyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018513265.1"
                     /locus_tag="EAO74_RS05840"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05850"
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="WP_187281731.1"
                     /sec_met_domain="Glycos_transf_2 (E-value: 1.6e-12,
                     bitscore: 41.5, seeds: 256, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKLGAVIITMGNRPDELRALLDSVAKQDGDRIEVVVVGNGAPVPD
                     VPPGVRTVELPENLGIPGGRNVGIEAFGPSGADVDALLFLDDDGHLPNTDTAELCRQAF
                     EADPKLGIITFRIADPETGVTQRRHVPRLRASDPMRSSRVTTFLGGANAVRSQVIAEAG
                     PLPGEFFYAHEETDLAWRALDAGWMIEYRADMVLNHPTTAPSRHAVYHRMVARNRVWLA
                     RRNLPAPLVPLYVGVWLLLTLVRRPSLPALKAWFGGFREGWTKPCGPRRPMRWRTVWRL
                     TRLGRPPVI"
     gene            complement(19691..20470)
                     /locus_tag="EAO74_RS05845"
                     /old_locus_tag="EAO74_05855"
     CDS             complement(19691..20470)
                     /EC_number="2.7.8.-"
                     /GO_component="GO:0005886 - plasma membrane [Evidence IEA]"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0016780 - phosphotransferase activity, for
                     other substituted phosphate groups [Evidence IEA]"
                     /GO_process="GO:0008654 - phospholipid biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049651.1"
                     /locus_tag="EAO74_RS05845"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05855"
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="WP_124275913.1"
                     /transl_table=11
                     /translation="MQKPSIAELRPVVHPPGVKDRRSGEHWAGRLYMREISLRITRRLV
                     TTKITPNQLTYVMTVAGVLAAPALLVPGIPGALLGVLAVQLYLLFDCVDGEVARWKKQY
                     SLAGVYLDRVAAYLCDAAVLVGFGLRAADLWGTGRIDWLWAFLGTLAALGAILIKSETD
                     LVGVARHQGGLPPVKEAASEPRSSGMAFARRAAGALKFHRLILGIEASLVILVVAVLDT
                     VRDDLFFSRLAVAVMAGIALLQTVLHLVSILASSRLK"
     gene            complement(20448..21509)
                     /locus_tag="EAO74_RS05850"
                     /old_locus_tag="EAO74_05860"
     CDS             complement(20448..21509)
                     /GO_function="GO:0030554 - adenyl nucleotide binding
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-ADH"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1181: dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007452391.1"
                     /locus_tag="EAO74_RS05850"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05860"
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="WP_124275912.1"
                     /sec_met_domain="Fe-ADH (E-value: 1.5e-18, bitscore: 60.5,
                     seeds: 218, tool: rule-based-clusters)"
                     /sec_met_domain="DHQ_synthase (E-value: 1.2e-10, bitscore:
                     34.8, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPVLTRLIPSPVVVDIRRGAMDDLAGLLADQRISASGKLAIAISG
                     GSGRALRERLAPVLPGADWYPVADGTIDSAVRLADGIKGNRYDAVVGLGGGKIIDVAKY
                     AAARVGMPMVAVATNLSHDGLCSPVATLDNDNGRGSYGVPTPIAVVIDLDVIREAPARY
                     VRSGIGDAVSNISCVADWELAHEVQGEDIDGLAAAMARQAGEAVLRHPGGIGGDAFLKV
                     LAEGLVLTGISMSIAGDSRPASGACHEINHAFDLLYPKRAASHGEQVGLGACFAMHLRG
                     AHEDALHMASVLRRHGLPVLPDEIGFTAEEFVRAVDYAPQTRPGRFTILEHLNLSTDQI
                     RDAYADYAKAIHS"
     gene            complement(21497..22234)
                     /locus_tag="EAO74_RS05855"
                     /old_locus_tag="EAO74_05865"
     CDS             complement(21497..22234)
                     /GO_function="GO:0016779 - nucleotidyltransferase activity
                     [Evidence IEA]"
                     /GO_process="GO:0009058 - biosynthetic process [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064: glucose-1-phosphate
                     adenylyl/thymidylyltransferase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955403.1"
                     /locus_tag="EAO74_RS05855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05865"
                     /product="sugar phosphate nucleotidyltransferase"
                     /protein_id="WP_099177435.1"
                     /sec_met_domain="NTP_transf_3 (E-value: 2.3e-13, bitscore:
                     44.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIGLVLAAGAGRRLRPYTDTLPKALVPVDGEKTVLDLTLANFAEV
                     GLTEVAVVVGYRKEAVYARKAEFEATYGVTLTLIDNDKAEEWNNAYSLWCAREVLKKGV
                     ILANGDTVHPVSVEKTLLDARGKGQKIILALDTVKNLADEEMKVITEDGKGVRRITKLM
                     DPATATGEYIGVTLIEPEAAEELADALRTTFERDPDLYYEDGYQELVNRGFTVDVAPIG
                     EVTWVEIDNHDDLARGREIACLY"
     gene            complement(22231..24006)
                     /locus_tag="EAO74_RS05860"
                     /old_locus_tag="EAO74_05870"
     CDS             complement(22231..24006)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010058029.1"
                     /locus_tag="EAO74_RS05860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05870"
                     /product="DUF5941 domain-containing protein"
                     /protein_id="WP_187281739.1"
                     /transl_table=11
                     /translation="MRSLGFEVTAAADASEAAELLAAVPASRRVALVDPRFVGHVHALR
                     LGLTDPRFAAATIPGALTAQPEARPALLRALQRAVAAVGAGSPVAPPGAAPVTEERTVP
                     GRLAVALDAEGTAVQRPELGSLTATVPTGPEERSAAEAAVSAVDDEAVRLRSAVKAHDG
                     FFTTFFISPYSRYIARWCARRGLTPNQVTTASLITALIAAGSAATGTRGGYIAAGVLLL
                     FSFVLDCTDGQLARYSLQYSTMGAWLDATFDRAKEYAYYAGLALGAARGGDDVWVLALG
                     AMVLQACRHVVDFSFNEANHDAVSNTSPTAALSDKLDSVGWTVWLRRMIVLPIGERWAM
                     IAVLTAVTTPRIVFYALLIGCALAACYTTAGRLLRSLTRKAKRTDRAARALADLADSGP
                     LAQAVAAVLRRPGGGFTAPLLAFAGAVVMVAAALFTPYGGWLTVGAAVVYAVLAGLAVS
                     RPLKGALDWLVPPVFRAAEYCTVLVLAARSDVPHAVPAAFGLVSAVAYHHYDTVYRIRG
                     GTGAPPQWLVRTIGGHEGRTLVVAVLAAVLIHGSGFTTALTALAAAVALVVLVESIRFW
                     VSSSAPAVHDEGELA"
     misc_feature    24216..24231
                     /note="TFBS match to ClgR, Caseinolytic protease gene
                     regulator, confidence: weak, score: 21.5"
                     /tool="antismash"
     misc_feature    24228..24242
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: strong, score: 20.76"
                     /tool="antismash"
     gene            24293..25279
                     /gene="galE"
                     /locus_tag="EAO74_RS05865"
                     /old_locus_tag="EAO74_05875"
     CDS             24293..25279
                     /EC_number="5.1.3.2"
                     /GO_function="GO:0003978 - UDP-glucose 4-epimerase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006012 - galactose metabolic process
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: NAD_binding_4 (65-207). E-value:
                     3.7e-10. Score: 31.3. Matches aSDomain:
                     nrpspksdomains_EAO74_RS05865_NAD_binding_4.1"
                     /codon_start=1
                     /gene="galE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010: NAD-dependent epimerase/dehydratase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014152793.1"
                     /locus_tag="EAO74_RS05865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05875"
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="WP_147982900.1"
                     /sec_met_domain="RmlD_sub_bind (E-value: 4.8e-19, bitscore:
                     62.4, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 1.9e-13,
                     bitscore: 44.0, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTWLITGGAGYIGAHVAKAMTGAGEKVVVLDDISSGIEARLPADV
                     TLVRGSASDREVLDRVLAEHAVTGVVHLAAKKQVGESVEKPLLYYRENVTGLGVLLEAV
                     VAAGVRRFLFSSSAAVYGVPDVDLITEETPCAPINPYGETKLAGEWLVRATGRAHGIST
                     ACLRYFNVAGAAEPELADTGVFNVVPMFFDRLTRGETPRIFGDDYPTPDGTCVRDYIHV
                     ADLADAHLAVAAHLDRSADGGDLTVNIGRGEGVSVRRLAELVGEVTGLPAEPVVEPRRP
                     GDAARAVASAARMTEELGWTARRGMREMVESAWEGWCLHHPEARTAR"
     CDS_motif       24296..24382
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_EAO74_RS05865_0001"
                     /evalue="1.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="EAO74_RS05865"
                     /protein_end="30"
                     /protein_start="1"
                     /score="17.4"
                     /tool="antismash"
                     /translation="TWLITGGAGYIGAHVAKAMTGAGEKVVVL"
     aSDomain        24488..24913
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_EAO74_RS05865_NAD_binding_4.1"
                     /evalue="3.70E-10"
                     /label="EAO74_RS05865_NAD_binding_4.1"
                     /locus_tag="EAO74_RS05865"
                     /protein_end="207"
                     /protein_start="65"
                     /score="31.3"
                     /tool="antismash"
                     /translation="AVTGVVHLAAKKQVGESVEKPLLYYRENVTGLGVLLEAVVAAGVR
                     RFLFSSSAAVYGVPDVDLITEETPCAPINPYGETKLAGEWLVRATGRAHGISTACLRYF
                     NVAGAAEPELADTGVFNVVPMFFDRLTRGETPRIFGDD"
     misc_feature    complement(25381..25395)
                     /note="TFBS match to ZuR_variant_1, Zinc-responsive
                     repressor, confidence: weak, score: 18.72"
                     /tool="antismash"
     gene            25498..26439
                     /locus_tag="EAO74_RS05870"
                     /old_locus_tag="EAO74_05880"
     CDS             25498..26439
                     /GO_function="GO:0008324 - monoatomic cation transmembrane
                     transporter activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049646.1"
                     /locus_tag="EAO74_RS05870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_05880"
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="WP_124275909.1"
                     /transl_table=11
                     /translation="MGAGHDHGHTHGGPPPTGTAAAAYRGRLRVALFITLGVMVMEIVG
                     GLLADSLALIADAAHMATDALGLGMALLAIHFANRPAGPSRTFGFARAEILAALANCLL
                     LLGVGGYLVFEAVERFITPAQTRGGLAIAFAAIGLVANVVSLSLLMRGQRDSLNVRGAY
                     LEVVADTLGSVTVLVSAGIIMATGWQAADPIASLLIGLMIVPRTVKLLRETLDVLLESA
                     PKGVDMDEVRAHITALPGVLDVHDLHAWTITSGMPVLSAHVVVHQEMLDSIGHEKLLHE
                     LQGCLGHHFDVEHCTFQLEPSGHAEHEARLCH"
ORIGIN
        1 gcaccttcga ttgtgaccta cgcgaccgta ataagggatt gacgggtggt gagaaagacc
       61 acccggtcag tttttggtaa agccggaata agaagagggg cggtgcgccg ctgcgcaccg
      121 cccctctccc ttcagccttc agccgggagg gcgtcctcgg ccggtgtgtc tcagatggag
      181 acgccgtgcg aacgcaggta ggcgatcggg tcgacgtcgg agccgtagct cgggccggtc
      241 cggacctcga agtggaggtg cgggccggtg gagttgccgg tggtgccgga gaggccgatc
      301 tgctggccgc cggtgacggt ctggccggcc gagacctcca gcgaggacag gtgcgcgtac
      361 tgggagtaca tgccgtcctc gtgctggatg acgacctcgt tgccgtacga accgctccag
      421 cccgcggaga ccacggtgcc cggaccgatg gagcggacgc tggtgccgga ggccgcctgg
      481 aagtcggagc cggtgtggta gccgctggac cagctggcgc ccgaggcgcg gtactgggtg
      541 gtgacgttgg ggttctcgac cggggcggcc cagccggaac cggtgctctc cgacgcgccg
      601 gaatcggcgg tctcggcggc cggagcggcc gtcttctcgg ccggggcagc ggtcttctcg
      661 gccggagcgg ccttcttcgc cgccgacggg gcggacgtgg agggcgcggc ctcggcggag
      721 ccggacgcct tggcgccgag ggtcagcttc atgcccggga ggatcaggct cgggttctcg
      781 ccgacgacgt cgcggttgtc ctggtacagc ttctgccagc cgcccttgac cttcttctcg
      841 gccgcgatct tggccaggta gtcgcccgag accacggagt aggtcttcgg ggcgctcttc
      901 gcggcggggg cggaggccga ggcgctgtgc gcggcggcgg ccggtgcgga ctgctcggcc
      961 gcgtgggcgc cggtcgcgcc gatcagcggg agggcgagta cggcgcagcc ggtccctgcg
     1021 gcaaggaagc ctcgggagat cgggccggtc ttcgtacgac ggtgcttgcc ttttgcgggc
     1081 atggggcttt tcctctccgg cgcctgcgag gtgagctgtc gggttcggac tggagatgcc
     1141 cggccgcgcg gtgcgcgact tgacccctag ccgtaccgga tccctccggc cggcggctta
     1201 cctggttccc ccgctcctgc cacacgtgag tcggtgcgga ttccgggcgg cggcaggatt
     1261 aggcgttccg tccggattga ccgtgaccgt aagcgagccg ggacgccgtg aacaagccgt
     1321 ggattgtgaa ccggaatcgg cgcttcaatt ccggcgcaaa attcccgtca cactccgtgg
     1381 attacggatc ttggctttcc gcacggcgtc aggaataccc ctcaggatct tcaccacgca
     1441 ccgtcacgga tatgatcccg ctcacccggc tcacaccatc tcccgtacaa gcggggcatg
     1501 ttctgctaaa tgcaccaata cggacatggc gcgaccgccg ttccaccgga gagcccggag
     1561 ccacggccac cgagacggtt gcccgatgca gccatgtcgt atcgtcgcgg gcgtgccccc
     1621 gtcggcgagc ggcgccgacg cccgacactc caggagccct tgtgacgcag ctgccagagg
     1681 tcccgccggt cggccccgag ccgacggacg tcgacctgac cggtgtccgc aacttccgcg
     1741 acgtcggcgg gcttccgacc gtcgacggca gcgccgtgcg gtacgggcgc ctctaccgca
     1801 gcggccacct cgcccatgcc accgagtccg acgcggcttt cctcgcggga ctcgggctgc
     1861 acacgatctt cgacttccgc aacgccgccg accacaagct cgacggtctc gacgtggagc
     1921 tgcccggcgt ccggaatgtc agcattcctc tctccgaccc ggcggacggc gcggagttct
     1981 ggcggctggt gcgcgacggg aacatccagc agctgcgctc gatcctggcc gacggcaagg
     2041 gaacggaccg gatggtcgcc tcgtaccgtt cgatcatcaa ggaccgcacc ggcgaacaca
     2101 gccgtgtgct gcacgcgctg gccgaggaca gcgtgccggc actgatgcac tgcgcggcgg
     2161 gcaaggacag ggccggcctc tcggtcgcgg tctcactgct cgcggtcggg gtccccaagg
     2221 aggccatcga ggccgactac ctcaagtcga acgacgcgca ccgccgctac aaggtgcgcc
     2281 gcagcgacac ctcggcggtg ggcatgtccg acgaggtgat ggaactgctc aatccgctct
     2341 tcggcgccca cgccgaatat ctcgccgcgg cgttcgacac catcgacgag atctggggcg
     2401 gcaccgaccg ctatctccgc gaagggctga agatcagcga cgagacgcgc gcgaagctgc
     2461 gcgagcgtct cgtcgagggt gcgtgaggcc gggcgggtca gcctttgccg gccacggtga
     2521 agagcaggta gaggaaaccc gcgatgacgt gtccggccac caggtaggcg aagagacgga
     2581 tcacgacgcc acggggcatc cgccgctcct gtgtgtccgc gctcctgggc ctgcgcgggg
     2641 tgagcgggtc gtagtgctcc gaatcggaca tggcagtcct ctcttccggc cgctcgggcc
     2701 ggggtgacga agggtgcgct cggtcggacg ggtgcccggt cggccggtgc ccggtcgggg
     2761 cggtacccgg ccgcccggtg cgcaaccggg acggtgcgcg gccgggacgg tgcgcaatcg
     2821 gttcggcggg tggtcgggtc ggtacgggcg ggcgggcgtg cgggatcaga gccggtgcgt
     2881 cccgccgccc aggcacagct cggcggccgg gctctgcagc agcgtgtgga cgaagagcag
     2941 gcgcgccccg ccggtgtcgg gcgcggcgat ccggtgcggg gtgagcgagt cgaagtgcgc
     3001 gctgtccccc gggccgagat cgtgcacggt ctcgccgagc acgaccctga gcctgccgtc
     3061 gaggacgtac agccattcct ccccggggtg gacgcgcacg aggtcgctct cggcgccgtg
     3121 ggggacacgg acgtgcagcg cctgcatggc acgtcccggc gctccggcct ggcggtagag
     3181 ccagccgccc gcctcggtgc cgcgcggcgc gccctcgggt gctccgccgc ggacgatcgc
     3241 gtcacgttcg ggcggcatct cgcccaggag ctcggagacg gtcgtaccgt agacccgggc
     3301 gaggccgagc agcatgggca gcgaaggctg cctccggccc gtttcgagcc gggagaggtg
     3361 ggccggggag agccccgccc gtgccgccgc gccctccagg gtgaggccgc ggttacggcg
     3421 caggtcgcgt aggcgtggcg cgaccccggg gagctcgtcg gccacccctc cgtcaggagg
     3481 attcatgtct ccattgggcc ctaatctttc ctccgaggca aataacttgc ctcggaggca
     3541 aaaggaccag gatcagcggt tggccaccgc ctgcttcacc agggtcctgc cgaagtccca
     3601 catcagcccg cccccgctgt gcgcgtcgtc catgacggcg gtgaaggcgg tgacgaagcg
     3661 gtccacctcc ggttccccga tgaccagcgg gggaatcagc ttgatcacct ccaggtgatc
     3721 gccggagacc tgggtgagga tccggtgctt ctgcagcagc ggcaccacca ccatctgcgc
     3781 gaagagcccc ttacgggcgg cctgcagcat cgtccagcgg ctgcggagct tgagggagga
     3841 cggccggccg aactcgatgc cgatcatcag gccccggccg cgcacctcgt gcagcagctc
     3901 gtaacggccg acgagcgcgg cgaggcgctc gcgcagcaga tcaccggtgc gccgggcgtt
     3961 cgcgacgatc tcctcctgct ccatcacgga gaggacggcg agcccggcgg ccatcgcctg
     4021 ggcgttggac ccgaagctcg cggagtggac gaggacccgg tccatcgagg agtagacgcg
     4081 cttgaagatc cagtccttgc cgagcgtcgc gccgaccggg acgtacccgc cggagagcgc
     4141 cttggcgaca cagagcagat cgggttcgac gccctcctcg tgctggtacg cgtagaagtc
     4201 accggtcctg ccgagcccgg tctgcacctc gtcggcgatg agcacggcct tgtgccggtg
     4261 cagcagctcc tgcgcctccc gcaggaagcc gggaggcgag gcgtggacgc ccttgccctg
     4321 gatcggctcc acgaccagcc cggccacgtc cccgcgcttc agttcgcggc gcagcgcgtc
     4381 gaggtcgccg agcgggatgg cggtgtcggg cagcaggggc gcgaacccgt cgcggaagcc
     4441 cttctcgccg ttgacggaga gcgagccggt ggtcagcccg tggaaggcgt ggtcgcagta
     4501 gaggatccgt ggcttgccgg tggcgtaccg ggcgaacttc agcgcggtct cgaccgcctc
     4561 cgtgccgctg ttgccgaaga agacccggtc gaggtgcggg ctgtgcgcca gcagcctctc
     4621 ggcgagcagt cccggaagcg gctggcagtc gaagcgggtg aggtcggcga gcgaggcgtc
     4681 caggacgtcg tggagcgcct tgcgtacgac ggggtggtgc ctgccgagcc ccataacgcc
     4741 gaagccggcg agcatgtcga ggtagtcgtt gccctcctcg tcccagaagt gcgcaccctc
     4801 ggcccgttcg tagaccttgt cgaatccgag ggtgtggagc attcgcggca gctggtggtt
     4861 gaggtgccgg gtgtgcagct cgtaccgctc ggcgcctcgt tccgcgagga gccgccccag
     4921 gtcgaagccc ggccgttcgt ccttcatgcc ccgttctcct tcggcatgtt ccgctctccc
     4981 gctgccgtgc gacgctccag cgccgcgctg atgcttccgg cgatctccac cggtgtgagc
     5041 ccgatctcgg ccagcacctc gccgcgcccc gcgtgcgcga ggaactgctc ggggatgccg
     5101 tacgtccgca gcggtacgtc ggcaccggcg tcccgcagcg cctgcccgac ggcccagccg
     5161 accccgccgg acctgctgtt gtcctcgacg accgccacca gccggtgctg tgccgccagc
     5221 gcgggcagct gcgcgtcgac cggtttgacc cagcgcgggt cgacgaccgt gcagcggatc
     5281 ccggatccgg cgagcaggtc ggcagcctgc agacagaccg gggcgagcac tcccacggcc
     5341 accagcagga cgtcggcgtc cggggcccgg tgcaggacgt ccatcccgcc gatccgcccc
     5401 acggccatga ccggctcccc caccgactcc ttggggaagc ggatcaccgt cggcgcgtcg
     5461 tcgacgtcga cggcctcgcg cagctcctca cgcagccggt cggcgtcgcg cggggcggcg
     5521 atacggagcc cggggacgac ctggagcagg gacatgtccc acatgccgtt gtgcgagggg
     5581 ccgtcgggcc cggtgactcc ggcccggtcc agcacgaagg tcaccccgca cccgtgcagg
     5641 gcgacgtcca tcagcagctg gtcgaacgcc cggttgagga acgtcgcgta gacggcgacg
     5701 accgggtgca gacctccggt ggccagcccc gccgccgaga ccgcagcgtg ctgctcggcg
     5761 atcccgacgt cccagatccg gtcggggaac tcctccgcga aacgggtcag cccgaccggg
     5821 tgcagcatcg ccgcggtgat cgcgacgacg tccgggcgta cggcgccgat ctccgcgatc
     5881 tcgtcgccga agacggaggt ccaggacggc gcggcgggca ggacgagcgg ttcgcaggtc
     5941 agcgggtcca tcctgccgac ggtgtggaag cggtcggcgt cgtcggccag ggcgggcgga
     6001 aagccccggc ccttctcggt gatgcagtgc accaggaccg ggccgtggaa gcgcttggcc
     6061 cgctgcagtg cggcctcgac ggccgcggtg tcgtgcccgt cgaccgggcc gacgtacttg
     6121 agacccaggt cctcgaacat gccctggggg gcgaaggtgt ccttgaaccc cttcttcgcg
     6181 ccgtgcagcg acccgtacag cggcgggccg atgaccggtg tctgctggag cacgcccttg
     6241 ccccaggaca ggaagcgctc gtagccgtcg gtggtgcgca gggtggccag gtggttggcg
     6301 agtccgccga tggtcggggc gtacgaacgc tcgttgtcgt tcaccacgat gatcagcggg
     6361 cggtccctgg ccgcggcgat gttgttgagc gcctcccagg ccattccgcc ggtgagggcc
     6421 ccgtcaccga tgaccgccac gacatgacgc ccgcgctccc gcacctcgtc ggccttggcg
     6481 aggccgtcgg cccagccgag cacggtggag gcgtgggagt tctcgatgac gtcgtgctcg
     6541 gactcctcgc gggacgggta gccggagagg ccgcccttgc tgcgcagctt ggagaagtcc
     6601 tggcgccccg tcagcagctt gtgcacgtaa ctctggtgtc cggtgtccca caggatgcgg
     6661 tccacgggtg agtcgaagac ccggtgcagg gcgatggtga gttcgaccac gccgaggttg
     6721 gggccgagat ggccgcccgt cctcgccacc gcccggatga ggaacgtcct gatctcctcg
     6781 gcgagttcgc cgagctccgg tcggctcagt gccttgagat cctgcggccc cttgatggat
     6841 tccagcatcg tcatgcccgg gcccctctct ctgctcctgt tatcggctca cggtgactgc
     6901 ggggatcccg ctgggtgtcc ccgcctcctc catacccgcg cgatcttcat ggcctcctcg
     6961 atgagggtct ccacgatctt cgactccggg acggtcttga tgacctcgcc cttcacgaag
     7021 atctgcccct tgccgttgcc cgaggcgaca cccaggtcgg cctcacgggc ctcaccggga
     7081 ccgttgacga cacagcccat caccgcgacc cgcagcggca cctccatgcc ctccagaccc
     7141 gcactcacct ggtccgcgag cttgtacaca tccacctgcg cccgcccgca cgacggacac
     7201 gagacgatct ccagacgccg ctgcttcaga ttcagcgcct ccaggatctg cagnnnnnnn
     7261 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn
     7321 nnnnnnnnnn nnnnnnnnnn nnnnnnnnnn nnncccatca ccgcgacccg cagcggcacc
     7381 tccatgccct ccagacccgc actcacctgg tccgcgagct tgtacacatc cacctgcgcc
     7441 cgcccgcacg acggacacga gacgatctcc agacgccgct gcttcagatt cagcgcctcc
     7501 aggatctgca gcccgacctt gacctcctcg gccggcggag ccgacaacga gacccggatc
     7561 gtgtccccga tcccctccga gagcagcgca ccgaacgcca ccgccgactt gatcgtcccc
     7621 tggaacgccg gacccgcctc ggtcacaccc agatgcagcg gatagtccga ctgcgccgcc
     7681 agctgacggt aggcgttcac catcacgacc gggtcgttgt gcttcaccga gatcttgatg
     7741 tcccggaacc cgtgctcctc gaacagcgac gcctcccaca gcgccgactc caccaacgcc
     7801 tccggcgtcg ccttcccgta cttcttcagc agccgcgcgt ccagcgaacc cgcgttcacc
     7861 ccgatacgga tcggcgtccc cgcctcaccc gcggccttcg cgatctcctt gaccttgtcg
     7921 tcgaactgct tgatgttgcc cggattcacc cgcaccgccg cacagcccgc gtcgatcgcc
     7981 gcgaacacgt acttcggctg gaagtggatg tccgcgatca ccgggatctg cgacttccgc
     8041 gcaatcgtcg ccaacgcgtc cgcgtcgtcc tgcgtcggac acgccacccg cacgatctga
     8101 cagcccgacg ccgtcagctc cgcgatctgc tgcaacgtcg caccgatgtc cgacgtacgc
     8161 gtcgtcgtca tcgactgcac cgacacaggt gcgtccccgc cgaccgccac cgacccgacc
     8221 tggatgcgcc gcgaggggcg gcgcaccgcg agaggccggg ccggcagccc ggggagaccc
     8281 agtacgaccg gctctcctgg actcatgacg tcaccggttc ccgccgatcg tctcccgtgc
     8341 cgctcgcagg gactccttga gggatcccat ggtggcgagc accgcggtcg gctcgtagcc
     8401 gcagtgcgcc atgcagttgg cgcagcgcgg gtccttgccc cggccgtact tgtcccagtc
     8461 ggtgtcctcg atgagctccc ggtaggtggg gacgtacccg tcgctcatca ggtagcaggg
     8521 ccgctgccag ccgaagagcg agtagttggg gatcgcccag gccgtgcagg gaaagtcggc
     8581 cttgccttcc aggaagtcca ggaagagcgg ggagtggttg agcctccagc ggctgcggtt
     8641 gccgccggcg aaggacttct tgaagagttc gcgggtctgc tcgacgccca ggaagtgctc
     8701 ctggtcggga gccttctcgt aggcgtaggc cggcgagatc atcatctcgt cgaccttcat
     8761 ctcgtcgttg aggaagttca gcacctcgat gacggtctgc ggggtgtcgg tgttgaagaa
     8821 ggtggagttg gtggtgaccc ggaagccgcg ccgcttggcc tccttcatcg cctccaccgc
     8881 ctcgtcgaag acgccttcct tggcgaccga ctcgtcgtgc cgctcgcgca gcccgtcgat
     8941 gtgcacggcg aaggcgaagt agggcgacgg ggtgaacttg tcgagcttct tgcgcatcag
     9001 catggcgttg gtgcagagga agacgtactt cttcttcgcc accagctgac gcacgatctc
     9061 gtcgatctgc gggtgcatca gcggctcacc gccggcgatg gagaccatcg gggcgcctga
     9121 ttccagcacc gccccgaccg cctgggcgac cggcatgcgc tgcttgagca caccggcggg
     9181 gtgctggatc ttcccacagc cctcgcacgc gagattgcag gcgaacaggg gctccagttc
     9241 cacgatcagc gggaacttct cccgcttgcg gagcttctgt tcgaagagat acgtcgcaac
     9301 cttgatggac tgacggagcg gcatggccat ctgggctcac ctcctgggga gcagcaaaga
     9361 tcggtgccat tcatgaaaag ccggaaggac agcacggaga acgcggaatg ccgatattcc
     9421 accgcggacc gtgccgatac ggacgagctc atgctctgga gcgtccacga ccacccgtac
     9481 ggcggcaacc gggcgcgggc ccgnccgtac ggcggtgcga agggtggcgg cggactccat
     9541 gtccaccgcg atggccccgg tggcccggag cccggcccgc tcggggcccc ggacgacatg
     9601 tccggagccg ttgagcgggc cggtgtggac cgtacggccg ggcacggccc tgaccagcgc
     9661 gtcgaccagc aggccggtgc cggtgcaggc cgtggtgccg ccggagtccc gggtctcctc
     9721 ggccaccacg aggtcacccg ggtgcatgcc gggttccagc ccggcgcaga agccggaggc
     9781 gatgaccgcg gtgcctccgg cgccgtcctg ccccagtgcc agccggacgg cgttctccgc
     9841 ggccctgggc cccatcccgg acctgatgat gctcaccggt ccggggcccg ggacaccgcc
     9901 gctccgcccg gtgcgcaggg cgaagcgctc gatgccgagg gcgcaggcga tcagcagcgg
     9961 agtggtgggg cctggcggtt cctggggacc ccccatcgcg tcaggccccc ttgccggtgt
    10021 ccgcgccggc ggcggtggcg aaggggtccc cgtagacgta ccggccgagc gcggtcaggg
    10081 ggaagacctg ccggtacagg tggtagttga tggagaagtc ccacgggaaa ccggtcccgg
    10141 tgaagtgcgg ttcgtcccag gagccgtccg cctgctgggt gttggccagc caggcgacac
    10201 cccgctccac ggactgggtc tcccgctccc ccgcggccag cagggcgagg agcgcccacg
    10261 cggtctggga ggcggtcgat gcgccgtggc cgatccactt ctcctcgcgg taggagcgca
    10321 ggtcctcgcc ccagcccccg tcgtcgttct ggacggacgt gagccagtcg acggcccggc
    10381 gcaccgaggg gtgtgcggcc ggcagcccgg ccgcgatcag ggcgggcacc acggagcccg
    10441 tcccgtagat gtagttgacg ccccaccggc cgaaccaggc tccggtcgcc tcctgttcgg
    10501 cgagcagcca ctcgatgccc cggcgggtac gggggtcctg cgcccgtccc tcgacggcga
    10561 gcatctccac cacgtgtccg gtgacgtcgg ccgacggcgg gtcgatgacc tcaccgaagt
    10621 cgcagaacgg cagccggttg gggaacgggc tggtgttgtc cgcgtcgaag gctccccagg
    10681 caccgttgcg tgactgcatg ccgaggttcc agcgcacccc gcgctcgatg gccgcctcga
    10741 ccctggcggg gtcggggtgg ctgacgcggc gcagcgccag gacgacttcc gcggtgtcgt
    10801 cgatatcggg gtagttgtcg ttgtggaact cgaacgccca gccgccgggg gccagttcgg
    10861 gcttgcgtac ggaccagtcg ccgggccgta cgatctcctc ggcgagcatc cagtcggccg
    10921 ccttcacgag cgcggggtgg tcggggctca cccccgcgtc ggcgagggcg atggtggcga
    10981 ggcaggtgtc ccagaccggg gactggcagg cctccaccat gcgggcgccg tcctcacgcc
    11041 agacggtgaa ccggtcgagg gattcgagtc ccgcccgcat caccgggtgg tcgaggtcgt
    11101 agccgagcag gtgcagggcg atgacggagt acacagcggg gggctggatg ccgccccagc
    11161 agccgtcgtt ctcctggcgt tcgatgatcc agcgggcggc ggcgttcatc gcactgcgcc
    11221 gcagtctgcg cggtgccacc ttgtggtaga ggtgcagcgc cttgtcgagc cgctggaaga
    11281 caccgtccca actggctgcg ggagcagctg gcttgggagg attggggcac gccgggtcgg
    11341 cgtgcagttc gtccagggcg aagggggcgg gccgtacggg ccgcttcgcg gacacgatgg
    11401 tgagcggtac gatggtctga cgggcccagc agccgaagtc gtagatgttg agcgggaccc
    11461 acttggggaa gaacatcagc tcgggcggga gttccggcag gtcgtcccac ttccaccagc
    11521 cgaagagcgc gagccagatc cgggtgaaga cccgggattc cgcgatgccg ccctgttccc
    11581 tgacccagcc cgcggcccgt ctcatgtgcg ggtcgtccgg ccggtccccg gcgagccgca
    11641 gcgcgacgta cgcctcgatc gtggcggaga ggtcgggcgg cccctcgtag aaggtgttcc
    11701 aggtgccgtc gcccatctgc tcgccccgga tgaagcgggc ggcggccttg agggtgtccg
    11761 ggtcctggat gcccaggaac tgacggagca gcaggtcctc cgcgtccatg gtgacgttgg
    11821 tggcgaggtc gcccttccac cagccctgct cgtcctgcct gccgaggagg tgctccaccg
    11881 agcgttccgc ggctcgccgc gcgacggccg agatgtcgtc cggggcgatg gttggttcgg
    11941 tcggatcgct cgcggggact gcgcggaggt tcgcggcccc ggtgcttccg tcggtcgtcg
    12001 ctgtcatggc ttccccttcg tgcagtctgg tcctctgctg tgctggggtc tccgtcggcg
    12061 ggcgccccgt ggggcgcccg ccggcgactg cgagtcatat ctggatggtc atcatctctt
    12121 tcgtacgacc acgaagtcgg cgagctcggt gagctgcgcc cggactcgtt ccggcatgtc
    12181 gacgccgtgc agcgcctcga tggctacggt gtgctgacgg cgggcttcct gggcggtcca
    12241 ctcgcggccg cccgcctcct cgatgagtgc cgcacgggcg gcgaactcct cttcggagaa
    12301 gctgtcgaag tcgctgctct tggcgtcggc ggcgagcagc tcgcccagac gctccgaggc
    12361 cggtccgccc gcggcgagcg cggccacgac gggcagggac ttcttgcgct gacgcagatc
    12421 gctccacgtc tgcttgcccg tggactccgg gtcgccccag atcccgagca ggtcgtcgac
    12481 cgcctggaag gcgaggccga ggtggtagcc gtacgcctcc aaaacgtcgg cggtacggtc
    12541 gtcggccccg ccgagcacgg cgccgatgga gacggcgcag gcgagcaggg cgcccgtctt
    12601 gttgccctcc atctccaggc actcctcgac ggtgacccgc tcgcggtgct cgtaggagat
    12661 gtcctgggcc tgaccgtcga tcagcttgcg gctggccgtg gtcagccggc gggcggcccg
    12721 cccggcctcg acggtgccga gctccagcag gacctcgttg gccagcgcga acagcgcgtc
    12781 gccgacgagg atcgcctggg cggggccgtg caccttccac acggtgtcgc ggtggcggcg
    12841 ctgttcgtcg ccgtccatca ggtcgtcgtg cagcagcgag aagttgtgca cgagttcgac
    12901 agctacggct ccggggatcc ccgcctcggc gggggcgccg gccgcttccg cggacagcag
    12961 ggccagcgcg ggacgcacgg ccttgcctcc gtcgccgtcg gcaggccggc cctgggcatc
    13021 gatccagccg aagtgatagg ccgcgacggt gtccatgggc ggcgccagcc ggtccacggc
    13081 agctcgcagc accggcgctg acagggccct tccacgctcc agaagcgcgg tgacgtccgt
    13141 ggtgtccacc acggtgtcgt aagccggatt cgccggggtc acagactctc ctcttgttcc
    13201 ggtggtactg ctcatgccgc ctcctgcagc ggatgttcgt gtggcctgcc gagggcctgg
    13261 agtgcggcgt ccgcggcgct gaagccgctg cggacggcgc cctccatcgt ggcgggccag
    13321 cccgtggcgg tccatgcccc cgccaggagc agccctggtg cgcgcgtccg tgcacccggc
    13381 cgcaggcggc ccacgcccgg cgcgggtgcg aaggtcgcgg tgcgttcgcg ggtgacgaag
    13441 aagtcgcgga tcccggcgcc gcgagccgcc ggcaggagcc tttccagctc gggcaggtag
    13501 cgcttgcgca gttcggcgac gggcaggtcg atctcgtcct gcgccgcgga ctgggagacc
    13561 gcgacgtact gcccggcgcc ctggaggccg gaggattccg tgcggtcgaa gacccactgc
    13621 acgggtgagc cgatcgcggc gaagaacggc cggcgcagca ccttgcggtc gtagacgacg
    13681 tgcacgttca ggatcggtga gtcggtgagt tcgagcagcc ggccggggtc gtcgagcgcg
    13741 ccgtcgggca gcagccggtg ggtctcgccc tggggcacgg cgaggacgac ggtgtccgcc
    13801 tcgaagccct cgccgtcggt cccgacggtc cagcggccgt cctcggcgcg ggtgagggag
    13861 gcggcgcggg tccgcacgtg gatctcgacc ccggccgatt cgagggcctt gcgggcgagg
    13921 gtgtcgtgga ggtccccgag cggtacggcg gcccagccga tgtcggcggc accgggctcg
    13981 gagaggagcc ccgttttgaa caccttcgcg gccaggccca tggaggcgtg gggggcggtg
    14041 gcgttgagcg tggcgacgcc gacgaggtcc cagagcgcct cgatggtgcg gtcggactgg
    14101 ccctggcggc cgagccaggt ggcgaagtcg acgccgtcga gtgcggggtc ggcggggtcg
    14161 agacggccca gcgccagtgc ggcgcgggcg accccggcct tctccgcgag ggagaggtgc
    14221 gggtaggcgg cgagtccgcc ggcgaggtgc agcgggacgg gcagcccggt gcggcggagc
    14281 cgtccgagcc tcggtcccgc gggccggccg acgtcgagga cgggtacgtc gaggcggtcc
    14341 tgcagcggtg cgaggtgggc gccctcgatc cggtcgagga accagcggta tccggtgcag
    14401 cagcgcaggt acacgtgctg gccgttgtcg acggacaggt cgcctcggcg gaaggagaag
    14461 gcgagcccgc cgagccgggg gcggccttcg agcagggtca cgtcgagtcc cgcgtcggcg
    14521 aggcgcagcg ccgaggtgac gcctgcgagt ccgccgccga cgaccagcgc ccgggaggac
    14581 cgggggttcc ggccggtcat gcctgctccc ttcgccgtgt cgtcgcagac agggacgcgc
    14641 cggggcgtcc gggggttgcc cgctccgtac gtcggatcgg acccgtcatc agaccctccc
    14701 cctggccgtc cggcgcgaga tgtaccgcgc gtcgaggccg gagaggccgc gcaccgcaac
    14761 gtacgccttc tcatggccgg gcagcgagac cctgccgcgc aggaccgcct cgggatcgcg
    14821 ttcgatccgg tccaggagcc ggcggtagat gccggccatg gccgccacgc aggcaccgct
    14881 gcggcggtcc agcatgggca gcagccggta gccctcggcg aagagcgccc gggcgcgccg
    14941 cacctcgaag tgcaccaggc cggcgaagtc ggacccgggg ggcggggtgg cccggtggaa
    15001 gccggcggag cagccgaact tggcgaggtc gtcggcgggc aggtacgtac gcccgttgcc
    15061 cgcgtcctcg cgtacgtcgc gcaggatgtt ggtgagctgg agcgcgaggc cgagggtgtc
    15121 ggcgtactcc gcggcccgtt cggcgccggg ggcgcccgtc tccgtaccga agacgccgag
    15181 gctgagacgc ccgatggcac ccgcgacaca ccggcagtac gtcttcaggt cggcccaggt
    15241 ctcgtacgtc gcgccgcgca cgtccatcag gacgccgtcg atgagctcgt cgaggccgcc
    15301 gagcggcagc gggaaccggt gcgcggcgtc ggccagcgcg accgcgaccg ggtcggtgtc
    15361 gtcctcgtcg acggcgttgt cccggatcct gacgagcagt ccccgggtct cctccagccg
    15421 ggtgtgcttc gtctccggat ccagctcgcc gtcgccgatg tcgtcgaccc gacgggagaa
    15481 ggcgtacaac gccgacatgg cctgccgctt ctcgtacggc agcagtcgga tgccgtacgc
    15541 gaagttgcgg gcctgctgtc cggtcacggc ctcgcagtag ctgtacgcgg cctgtaccgg
    15601 tgccgacatg tacgtcgtct gtccctccac ggtccggttc acccctctct gtgcgctctt
    15661 cgcaggacgt ggcccacttc gcgcagcagt ccgggcgcgg tgggcttggg cggtccgggc
    15721 agtacgtcga atccggcggc ggtgatcgcg ccgagggcgg cccgtccgcc gccgacgaag
    15781 ccggcgagca gcagcctgag ccgtccgtgg acgctgccca ccagcgggat gccctcgtcc
    15841 agcaggtcgc gggcgcgctc cgcctcgaag gcgaccaggg cgcgcaccgc cgcgcctgcg
    15901 gacggtgccg ccaggtcgct ctcaccgatg tggaagcggg ccatgtcgtc ggcgggcaga
    15961 tagatccggt cgcggccgag gtcctcggcg acgtcctgga ggtgttcggc gatctgcagg
    16021 gcggtgcaga cggcgtcgga gcggcggatg cgttcggggc tcgcggtgcc ggtgatctgc
    16081 aggacgaggc ggccgacggg gttggcggag agctcgcagt aggcgagcag gtccgcgtag
    16141 gtcccgtagc ggcggatctt ctggtcctgc cggttggcct cgacgagccc gaggaagggt
    16201 tcgggggtga gcgcgcagcg ccgcacggtg gggcgcaggg cacgcatcag gggggcgcag
    16261 ggcacgcatc agggggtggc gggggccgtc gccggacggc gcgaagacgc ggtggagatc
    16321 ggcttcgagg gcgtccagcg cggcgagccg gtcgtcttcc tgtccggggt cgagtccgag
    16381 actgcgggcg tcggcgccgc cgggcgccag gtcgccgtca ccgatgtcgt cgacgagacg
    16441 ggcgaagccg tagacggcca tcaggtcgtc gcgccaggcg cggggcagga agaagggggc
    16501 cacggggaag ttctcgtcgg cggccttgtc cagcgtggcg gcggcgtcgg cgggcgcctg
    16561 ccgggtacgc gtcactgcgg accacccgac gcggggacgg cgaaacaacg tcgaagctgg
    16621 agattttcca tcattgccgt catatctccc gttctacact gccgacccaa aacatccctt
    16681 ttcggacacg ccgctcgtcc ggccgagtgc ggcatgcaca caacgggcga tgtgcggggg
    16741 cgtatcaccc cacatggccg cgaatcggca ccgtcacagc ttacgttgta cagctcacaa
    16801 gcccgcgccg gggtgcagcg cgccctcgtg caacacaccg gccgccgtca accttccccg
    16861 gatccgggtc gattgacgtc atccgtcggg aggagatcca cccgggcacc taccgcccct
    16921 gtgggtcctc accaccacga cgcgcacacc gcagggcccc cgccgtccgg cgggggccgc
    16981 acacacaggg cggctacttg ccggtctccc gctcgtaggc cttcagcacc tcgtcggtgg
    17041 ggccgtccat caggagctcg cccttctcaa gccacagcac ccggtcgcag gtgtcgctga
    17101 tggtcttgtt gttgtggctg accaggaaga cggtgcccgc ctccttgcgc agctcgcgga
    17161 tccgctcctc ggagcgcacc cggaacttcc ggtcaccggt ggccagcgcc tcgtcgatca
    17221 tgaggacgtc gtggttcttg gcggccgcga tggagaagcg cagcctggcc gccatgccgg
    17281 aggagtacgt ccgcatgggc agcgtgatga agtcgccctt ctcgttgatc ccggagaaat
    17341 ccacgatgtc ctggtaccgc gtgcggatct cctcgcggct catgcccatc gcgaggccgc
    17401 cgagcacgac gttgcgctca ccggtcaggt cgctcatcag ggccgcgttg acaccgagca
    17461 gcgacggctg gccgtcggtg tacaccttgc cgtgctcggt cggcagcaga ccggcgatgg
    17521 cccggagcag ggtggacttg ccggaaccgt tggtgccgat gaggccgatg gcctgcccgc
    17581 ggtacgcggt gaaggagacc ccccgcaccg cgtgcacctt gcgcacaccg cgtggctcgc
    17641 ccttgccgcg ccgcatgatc cggctcagtg ccgcggtggc gctgcccttg ccgccacccg
    17701 tgccgttgac gcggtacacg atgtgcacat cgtccgcgat cacggtgggg atgtgtccct
    17761 gggacgattc ctcagccacg gccgtaccgt tcctctgcct tccagaagta cacgaagccc
    17821 acgacgccca ccacgagcgc ccaggcgagc ccgaccgccc agacgtgctg cggcaggttc
    17881 tccgagccgt agccgtcgat cagcgcgaag cggaccaggt ccatgtagat ggccgccggg
    17941 ttgtactgca gcacgtcggc gatccactgc ggcttgccct cgagcatcac ggggatggag
    18001 aacatcacgc ccgagccgta catccacgta cgcatgacga acggcatcag ctgcgcgagg
    18061 tcgggggtct tgctgcccag ccgggccatg acgagcgcca ggccggtgtt gaagaggaac
    18121 tgcatggcca gcgccgggat gatgagcagc caggacagcg acgggtagct gccgaagccc
    18181 accgccacgg ccagcagcac gatcatggag tagagcagct gctggagctg ctgcagcgag
    18241 aacgagacgg gcagcgaggc ccgggggaag tgcagcgccc tgaccaggcc gatgttgccg
    18301 gagatggagc gcaccccggc catcaccgag ctctgggtga aggtgaagac gaagaccccg
    18361 gtcaccagga acgggatgaa gacctcctgg ctcatccccc ggttggtgcc caggatcagg
    18421 ccgaagatca ggaagtagac cagggcgttc agcagcgggg tggccacctg ccacagctgg
    18481 ccgagcttgg cctggctgta ctgcgcggtc agcttcgccc tcgagaacgc caggatgaaa
    18541 tgccgacggc cccagagctg acggatgtac gcgaacagcc ctggccgggc gccgctgacc
    18601 gtcaagccgt acttggcggc cagctgggac gcgctcagtc cctcgtcggc ggacggcggg
    18661 ctgctcagcg caatcccgcc gtcgtgggtc gtgtcactca cagttaagaa ctctcgtctt
    18721 cacgatgcgc agcaggtcgc gggcgcggcc agggcggaca ggttccccgt acggaatgaa
    18781 tacggctcat ggtctcagag gagagcctct cagatcaccg gcgggcggcc cagtctggtc
    18841 agccgccata ccgtacgcca cctcatcggg cgccggggtc cgcagggctt ggtccagcct
    18901 tcccggaaac ccccgaacca tgctttgaga gcgggcaggg agggccggcg gaccagcgtg
    18961 aggagcagcc agaccccgac gtagaggggg accagcggcg cgggcaggtt ccggcgggcg
    19021 agccagacgc ggttgcgggc caccatgcgg tggtagaccg cgtgccgtga cggcgcggtg
    19081 gtggggtggt tgagcaccat gtccgcgcgg tactcgatca tccagccggc gtcgagggcc
    19141 cgccaggcga ggtcggtctc ctcgtgcgcg tagaagaact cgccggggag cgggccggcc
    19201 tcggcgatca cctggctgcg cacggcgttc gcgccgccga ggaaggtcgt gacacgggag
    19261 gagcgcatcg ggtcggaggc gcgcagccgc ggcacgtgcc ggcgctgggt gacaccggtc
    19321 tccgggtccg cgatgcggaa ggtgatgatg ccgagcttgg ggtccgcctc gaacgcctgc
    19381 cggcagagct cggcggtgtc ggtgttgggc aggtgcccgt cgtcgtcgag gaagagcagg
    19441 gcgtccacat cggctccgga cgggccgaac gcctcgatgc cgacgttgcg gccgcccggg
    19501 atccccagat tctcgggcag ctcgacggtc cgtacgcccg gggggacgtc ggggaccggg
    19561 gcgccgttgc cgacgacgac cacctcgata cggtcgccgt cctgcttggc gaccgagtcg
    19621 aggagggcgc gcagttcgtc gggccggttg cccatggtga tgatgaccgc gccgagtttc
    19681 atgggagagc tcacttcagc ctgctggacg ccaggatcga caccaggtgc aggacggtct
    19741 ggagaagggc gatgccggcc atgaccgcga ccgcgaggcg gctgaagaag aggtcgtccc
    19801 tgaccgtgtc gaggacggcc acgaccagga tgaccagcga cgcctcgatg ccgaggatca
    19861 gccggtggaa cttgagcgcg ccggcggccc ggcgggcgaa cgccatgccg gaggagcgcg
    19921 gctcggaggc ggcctccttg acgggcggca gcccgccctg gtggcgggcg accccgacga
    19981 ggtcggtctc ggacttgatc aggatggcgc cgagcgcggc gagcgtgccc aggaaggccc
    20041 acagccagtc gatgcggccc gtgccccaca ggtcggcggc gcgcaggccg aagccgacca
    20101 gcaccgcggc gtcgcacaga taggcggcca cccggtccag atagacgccg gccagggagt
    20161 actgcttctt ccagcgggcc acttcgccgt cgacgcagtc gaacagcagg tagagctgga
    20221 cggcgagcac gccgagcagg gcgcccggga tgcccgggac cagcagggcg ggagccgcga
    20281 gcacaccggc gacggtcatc acgtaggtca gctggttcgg cgtgatcttc gtggtgacca
    20341 ggcgccgggt gatgcgcagg gagatctcgc gcatgtagag acggcccgcc cagtgctcgc
    20401 cactgcgccg gtccttcacg cccggggggt gcacgaccgg acggagttca gctatggatg
    20461 gcttttgcat agtcggcgta cgcgtccctg atctggtcgg tggacaggtt gaggtgttcc
    20521 aggatcgtga agcgtcccgg gcgcgtctgc ggggcgtagt cgacggcccg tacgaattcc
    20581 tcggcggtga agccgatctc gtcgggcagc accgggagcc cgtggcgccg caggacggac
    20641 gccatgtgca gcgcgtcctc gtgggcgccc cgcaggtgca tggcgaagca ggcgccgagg
    20701 ccgacctgct cgccgtggct ggccgcgcgc ttcgggtaca gcaggtcgaa ggcgtggttg
    20761 atctcgtggc aggcgcccga ggcgggccgc gagtcaccgg cgatcgacat cgagatgccg
    20821 gtcaggacga gcccttcggc gagcaccttg aggaaggcgt cgccgccgat cccgccgggg
    20881 tggcgcagca cggcctcgcc ggcctgccgg gccatggcgg ccgcgagccc gtcgatgtcc
    20941 tcgccctgga cctcgtgggc gagctcccag tcggcgacgc acgagatgtt ggagacggcg
    21001 tcgccgatgc ccgagcgcac gtagcgcgcg ggggcctcgc ggatgacgtc gaggtcgatg
    21061 accacggcga tcggggtcgg gacgccgtag gagccccgcc cgttgtcgtt gtccagggtc
    21121 gcgaccgggg agcagagccc gtcgtgggag aggttcgtcg cgacggcgac catgggcatg
    21181 cccacgcgcg ccgcggcgta cttcgccacg tcgatgatct tgccgccgcc gaggccgacg
    21241 acggcgtcgt agcggttgcc cttgatgccg tcggcgagcc gcaccgcgga gtcgatcgtg
    21301 ccgtcggcga ccgggtacca gtcggcgccc gggagcaccg gggcgagccg ttcgcgcagg
    21361 gcgcggccgg agcctccgct gatcgcgatg gcgagcttgc ccgaggcgga gatccgctgg
    21421 tcggcgagga gaccggccag atcgtccatc gcgccgcgcc ggatgtccac gacgacgggg
    21481 gacgggatga ggcgggtcag tacaggcacg cgatctccct gcccctggcg aggtcgtcgt
    21541 ggttgtcgat ctccacccac gtcacctcgc cgatgggcgc gacgtcgacg gtgaagccgc
    21601 ggttcacgag ctcctggtaa ccgtcctcgt agtagaggtc ggggtcgcgc tcgaaggtgg
    21661 tccgcagcgc gtcggcgagc tcctcggcgg cctcgggctc gatgagggtg acgccgatgt
    21721 actcgccggt cgcggtggcc gggtccatca gcttggtgat ccgccggacg cccttgccgt
    21781 cctcggtgat gaccttcatc tcctcgtcgg cgaggttctt caccgtgtcg agggcgagga
    21841 tgatcttctg gcccttgccg cgcgcgtcca ggagggtctt ctcgacggag accgggtgca
    21901 cggtgtcgcc gttggcgagg atgacgccct tcttcaggac ctcacgggcg caccagaggg
    21961 agtaggcgtt gttccactcc tcggccttgt cgttgtcgat gagcgtcagc gtcacgccgt
    22021 acgtggcctc gaactcggcc ttgcgggcgt agaccgcctc cttgcggtag ccgacgacga
    22081 cggcgacctc ggtgagcccg acctcggcga agttggccag cgtgaggtcc aggaccgtct
    22141 tctcgccgtc caccggcacc agggccttgg gcagcgtgtc cgtgtaggga cgcagacggc
    22201 gtccggcacc ggcagccagt acgaggccga tcatgcgagt tctccttcgt cgtgtacggc
    22261 gggggccgag gaggacaccc agaagcggat ggactccacg agcaccacca gagccacggc
    22321 ggccgcgagc gcggtgagag ccgtggtgaa acctgaaccg tggatcagta cggcggcgag
    22381 tacggccacg accagggtcc ggccctcgtg tccgccgatg gtgcgcacca gccactgggg
    22441 cggcgctccg gtgccgcccc ggatgcggta caccgtgtcg tagtgatggt aggcgacggc
    22501 cgaaaccaga ccgaatgccg cgggaacggc gtgcggcacg tcactgcgcg cggccagcac
    22561 caggaccgtg cagtactcgg cggcccggaa gaccggcggg accagccagt cgagggcgcc
    22621 cttcagcgga cgtgagacgg cgagcccggc caggaccgcg tacaccacgg cggcgcccac
    22681 ggtcagccag ccgccgtacg gggtgaacag tgccgcggcg accatgacca cggctccggc
    22741 gaacgccagg agcggggccg tgaagccgcc gcccgggcgc cggagcacgg cggcgacggc
    22801 ctgggcgagc ggtcccgagt cggcgaggtc ggccagggcc cgggcggccc ggtcggtgcg
    22861 cttcgccttg cgggtcagcg agcggagcag ccggccggcc gtggtgtagc aggcggccag
    22921 ggcgcagccg atgagcaggg cgtagaagac gatccggggt gtggtcacgg cggtgagcac
    22981 ggcgatcatg gcccagcgtt cgccgatggg cagcactatc atccggcgca gccagaccgt
    23041 ccagccgacg ctgtcgagct tgtcggagag cgcggcggtg gggctggtgt tggagaccgc
    23101 gtcgtggttg gcctcgttga acgagaagtc cacgacatgg cggcaggcct ggagcaccat
    23161 cgcaccgagc gcgagcaccc agacgtcgtc gccgccccgg gccgccccga gggcgaggcc
    23221 cgcgtagtac gcgtactcct tggcccggtc gaaggtggcg tccagccagg cgcccatcgt
    23281 cgagtactgg agcgagtagc gggcgagctg cccgtcggtg cagtccagga cgaaggagaa
    23341 gaggagcagc acgccggccg cgatgtagcc gccccgggtg ccggtcgccg cgctgccggc
    23401 cgcgatgagc gcggtgatca gcgaggccgt ggtgacctgg ttcggggtga ggccccggcg
    23461 ggcgcaccag cgggcgatgt agcgggagta cgggctgatg aagaacgtgg tgaagaagcc
    23521 gtcgtgggcc ttgaccgcgc tgcgcagccg tacggcctcg tcgtcgacgg cggacacggc
    23581 ggcctcggcg gcactccgct cctcgggccc ggtggggacc gtggccgtga gcgaaccgag
    23641 ctcggggcgc tgtacggcgg tgccctccgc gtccagggcc acggccagcc ggccgggcac
    23701 ggtgcgctcc tcggtgacgg gcgcggcgcc ggggggtgcg acggggctcc cggcaccgac
    23761 ggcggccacg gcccgctgga gggcgcgcag cagcgcgggg cgggcctcgg gttgcgcggt
    23821 gagcgccccg gggatcgtcg cggcggcgaa gcgggggtcg gtgagtccga gcctgagcgc
    23881 gtggacatgg ccgacgaaac gggggtccac gagcgcgacg cgcctgctcg cggggactgc
    23941 cgcgagcagc tcggcggcct cggaggcgtc agctgcggca gtgacttcga agccgagcga
    24001 ccgcagatcg tcctcgagcg acgatccggg taccggcgca ccggtgagga tggcggtcga
    24061 cagacgaact cactccttgg ggcgctgacg ggaacggcgc gcgaacatgc ggcccggagg
    24121 tgggccggcg gcacgtcggc tgaggctatc ggatgaacgg aaggccgagt tcaccgcccg
    24181 tttgtgctcc gttcgggcga atcggccatc atgcggcgcc gttcgcgatc atcatcgtcg
    24241 atcaacgcct cgacccacaa accgcgtccg gacagcgcat aggctgaggg gcatgacgtg
    24301 gttgatcaca ggcggagccg gttacatcgg ggcacatgtg gcgaaggcca tgacgggggc
    24361 cggggagaag gtcgtcgtcc tcgacgacat ctcgtcgggc atcgaggcgc ggctgcccgc
    24421 cgacgtcacg ctggtgcggg gctcggcctc ggaccgtgag gtgctcgacc gggttctggc
    24481 ggagcacgcc gtcacgggtg tggtgcacct cgcggcgaag aagcaggtcg gtgagtccgt
    24541 cgagaagccg ctgctgtact accgggagaa cgtgaccggg ctcggcgtgc tgctcgaggc
    24601 cgtcgtcgcg gccggtgtgc ggcgcttcct cttctcctcg tccgcggcgg tgtacggcgt
    24661 cccggacgtg gacctgatca cggaggagac gccctgcgcg ccgatcaacc cgtacgggga
    24721 gaccaagctc gccggggagt ggctggtgcg cgcgacgggg cgggcccacg gcatctcgac
    24781 ggcctgcctg cggtacttca acgtggccgg ggccgccgag cccgagctgg ccgacacggg
    24841 cgtcttcaac gtcgtaccga tgttcttcga ccggctgacg cggggcgaga ccccgcggat
    24901 cttcggtgac gactacccga cgccggacgg cacctgtgta cgcgactaca tccatgtcgc
    24961 cgacctggcg gacgcgcatc tcgccgtcgc cgcgcacctc gacagaagcg cggacggcgg
    25021 ggacctcacg gtgaacatcg gccggggcga gggagtgtcg gtgcgccggc tcgccgagct
    25081 ggtgggggag gtcaccgggc tgccagcgga gcccgtggtc gagccgcgga ggcccgggga
    25141 cgcggcccgc gcggtcgcct ctgccgcccg gatgaccgag gagctgggct ggacggcacg
    25201 tcgcggcatg cgcgagatgg tggagtcggc ctgggagggc tggtgcctgc accacccgga
    25261 ggcccgcacg gcgcggtgag ccaccgcgct ccggcgacgc gcacgccggt ggcgcccaca
    25321 ccggtgacgc tcacccccgc aaggctctga cctgcgaacg tttccgcagg tcagagcaca
    25381 tgacaacggt gttcagtgcc gtgttgcccc ttacccctcc cccgtagttc actggccgca
    25441 tcgggcgagg tgcgcccgtg ctgtccgagg gacacgacgg gttgcggagg cgttcgcatg
    25501 ggggctggcc acgatcacgg gcatacgcac ggagggccgc ccccgacggg cacggccgcc
    25561 gccgcgtacc ggggcaggct ccgggtcgcc ctgttcatca cgctcggcgt catggtcatg
    25621 gagatcgtgg gcgggctgct cgccgactcg ctcgccctga tcgccgatgc ggcccacatg
    25681 gccaccgatg ccctggggct gggcatggcc ctgttggcca tccacttcgc caaccggccg
    25741 gcgggcccca gccgcacctt cggcttcgcc cgtgcggaga tcctcgcggc gctggccaac
    25801 tgcctgctgc tcctcggtgt cggcggctat ctggtcttcg aggccgtcga gcgcttcatc
    25861 accccggccc agaccagggg cggactggcc atcgccttcg cggccatcgg tctggtcgcc
    25921 aacgtcgtct cactgtcgct gctgatgcgc gggcagcgcg acagcctcaa tgtgcggggc
    25981 gcctatctcg aggtcgtcgc ggacacgctc ggttcggtga cggtgctcgt gtcggcgggc
    26041 atcatcatgg cgacgggctg gcaggcggcc gaccccatcg cctcgctgct catcggcctc
    26101 atgatcgtcc cccgtacggt gaagctcctg cgggagacgc tcgacgtact gctggagtcg
    26161 gcgcccaagg gggtcgacat ggacgaggta cgcgcccaca tcacggctct cccgggcgtg
    26221 ctggacgtgc acgacctgca cgcgtggacg atcacctcgg gcatgcccgt gctctccgcc
    26281 catgtggtcg tgcaccagga gatgctggac tccatcggcc acgagaagct cctgcacgaa
    26341 ctccagggct gcctcggcca ccacttcgac gtggagcact gcaccttcca gctggagccc
    26401 agcggccacg cggagcacga ggcgcggctc tgccactgag ccgcccgcgc gccgtcgccc
    26461 ggtgctaggg tctgcggcga gtctccgagc ccggagcccg tggggagaga aggagctgag
    26521 gttgatgacg gtcgtcacga cggctgcccg gtgcagcgtc cggtccttcc tcgtc
//
