LOCUS       NZ_RDBM01000011        11074 bp    DNA     linear   CON 01-JAN-2025
DEFINITION  Streptomyces sp. gb1(2016) Scaffold_11, whole genome shotgun
            sequence.
ACCESSION   NZ_RDBM01000011
VERSION     NZ_RDBM01000011.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces sp. gb1(2016)
  ORGANISM  Streptomyces sp. gb1(2016)
            Bacteria; Bacillati; Actinomycetota; Actinomycetes;
            Kitasatosporales; Streptomycetaceae; Streptomyces.
REFERENCE   1  (bases 1 to 259573)
  AUTHORS   Hariharan,J., Choudoir,M.J., Diebold,P., Panke-Buisse,K.,
            Campbell,A.N. and Buckley,D.H.
  TITLE     Direct Submission
  JOURNAL   Submitted (16-OCT-2018) Soil and Crop Sciences, Cornell University,
            306 Tower Road, Ithaca, NY 14850, USA
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 2018
            Assembly Method                   :: A5+MeDuSa v. JUNE-2018
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 66x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008042065.1-RS_2025_01_01
            Annotation Date                   :: 01/01/2025 02:23:01
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.9
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 7,414
            CDSs (total)                      :: 7,333
            Genes (coding)                    :: 6,887
            CDSs (with protein)               :: 6,887
            Genes (RNA)                       :: 81
            rRNAs                             :: 6, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 6, 1, 1 (5S, 16S, 23S)
            partial rRNAs                     :: 1 (23S)
            tRNAs                             :: 69
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 447
            CDSs (without protein)            :: 446
            Pseudo Genes (ambiguous residues) :: 0 of 447
            Pseudo Genes (frameshifted)       :: 94 of 447
            Pseudo Genes (incomplete)         :: 395 of 447
            Pseudo Genes (internal stop)      :: 7 of 447
            Pseudo Genes (multiple problems)  :: 48 of 447
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 13:17:57
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 1970
            Orig. end                         :: >13044
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            RDBM01000011.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..>11074
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..>11074
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..>11074
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:>6074]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..>6074
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     gene            complement(588..1148)
                     /locus_tag="EAO74_RS03000"
                     /old_locus_tag="EAO74_03000"
     CDS             complement(588..1148)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1057: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575712.1"
                     /locus_tag="EAO74_RS03000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03000"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_147982563.1"
                     /transl_table=11
                     /translation="MGRVSQAQAEENRRRVVDTASRLFREQGTHVSVADLMKAAGLTHG
                     AFYKQFASKEALVDEATVHAFSELAQRYSAGLERHDGQRGAAQQALIDTYLSVEHRDDP
                     ADGCPVAALATDIARESGGSEARRAYAEGVADFAGFLATDGEDGIVRLCTLFGALVLAR
                     ATKDSPLSREILDAARAALAEAG"
     gene            1263..1955
                     /locus_tag="EAO74_RS03005"
                     /old_locus_tag="EAO74_03005"
     CDS             1263..1955
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015575713.1"
                     /locus_tag="EAO74_RS03005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03005"
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_147982564.1"
                     /transl_table=11
                     /translation="MELKNTVAVVTGANRGLGRHLAAQLVERGAKVYAAARRPETVDLP
                     DVTPLRLDVTDHESIREAARVASDATLLINNAGISTGATLVGGGLDEVRREMETNFFGP
                     LVATRAFAPVIEGNGGGAVLNVLSALSWFHPAALGSYAASKAAAWALSDATREELAPRG
                     ITVSALHVGYMDTDMAAGVPADQKVAAADVAAQALDGVEAGLPEMLADEASRYVKQSLS
                     AAPQPTEG"
     misc_feature    complement(2062..2077)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 16.95"
                     /tool="antismash"
     gene            2416..2841
                     /gene="panD"
                     /locus_tag="EAO74_RS03015"
                     /old_locus_tag="EAO74_03015"
     CDS             2416..2841
                     /EC_number="4.1.1.11"
                     /GO_function="GO:0004068 - aspartate 1-decarboxylase
                     activity [Evidence IEA]"
                     /GO_process="GO:0006523 - alanine biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="panD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964661.1"
                     /locus_tag="EAO74_RS03015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03015"
                     /product="aspartate 1-decarboxylase"
                     /protein_id="WP_147982566.1"
                     /transl_table=11
                     /translation="MMRTMFKSKIHRATVTQADLHYVGSVTIDADLMDAADLLPGELVH
                     IVDIDNGARLETYVIAGERGSGVIGINGAAAHLVHPGDLVILISYAQVDDAEARALVPS
                     VVHVDAANRIVAVGADASEPVPGSRTERSPQAVPAQG"
     gene            2880..3239
                     /locus_tag="EAO74_RS03020"
                     /old_locus_tag="EAO74_03020"
     CDS             2880..3239
                     /EC_number="2.3.1.-"
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955645.1"
                     /locus_tag="EAO74_RS03020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03020"
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="WP_129259861.1"
                     /transl_table=11
                     /translation="MAEERTAVEIRDDREHGKLVALDEGGSVAGTIAYFVMYPEPGALV
                     GVHTVVRPEHEGKGVAGALAREFYALAARQGVPVVPLCPYLAAWAERHPEQAPKAPDEL
                     VRGAERQLGSHPELF"
     gene            complement(<3293..>3451)
                     /locus_tag="EAO74_RS03025"
                     /old_locus_tag="EAO74_03025"
                     /pseudo=""
     CDS             complement(<3293..3451)
                     /GO_function="GO:0008080 - N-acetyltransferase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955645.1"
                     /locus_tag="EAO74_RS03025"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /old_locus_tag="EAO74_03025"
                     /product="GNAT family N-acetyltransferase"
                     /pseudo=""
                     /transl_table=11
                     /translation="MGVHTVVRPEHEGKGVAGALAREFYALAARQGVPVVPLCPYLAAW
                     AVRLPSPA"
     gene            complement(3595..4881)
                     /locus_tag="EAO74_RS03030"
                     /old_locus_tag="EAO74_03030"
     CDS             complement(3595..4881)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_Arg_deC_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Orn_DAP_Arg_deC"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1264: diaminopimelate decarboxylase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015579899.1"
                     /locus_tag="EAO74_RS03030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03030"
                     /product="diaminopimelate decarboxylase"
                     /protein_id="WP_147982697.1"
                     /sec_met_domain="Orn_Arg_deC_N (E-value: 6.5e-36, bitscore:
                     117.8, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 6.7e-10,
                     bitscore: 33.1, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEGLLGEERPLAGFLDADGIRESADALRDAFAAEPGVRVLHTFA
                     AKAASLIPVLRLLADCGMGCEVAGPGELRLAVEAGFAPARIVLDSPAKTRDELRLALAL
                     GVAVNADSFGEIRRIEGLRSPGSASVLGLRVNPQVGGGSIGAMSTATATSKFGVALRDP
                     GARDRVVQTFVERPWLTRLHAHVGSQGCSLDLIAAGIAETYRLAEEINGVLGTRRVTGI
                     DIGGGLPVNFDDDETRPAFAEYVAALRSAAPGLFDGRYDLVTEFGRSLLAKNGFIGARV
                     EYTKDAGGRRIALTHAGAQIATRTVFMPDAWPLRIGAFDGEGRPRGGPPMVQDIAGPCC
                     FAGDVVAHARELPELREGDFVVLYDTGAYYFSTPWAYNSLPRPAVYGFAGETGSLRFAP
                     VREAQSLDSVAAESGLRHAGALTGLHGRP"
     gene            complement(5001..5798)
                     /locus_tag="EAO74_RS03035"
                     /old_locus_tag="EAO74_03035"
     CDS             complement(5001..5798)
                     /GO_component="GO:0140737 - encapsulin nanocompartment
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018955648.1"
                     /locus_tag="EAO74_RS03035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03035"
                     /product="family 1 encapsulin nanocompartment shell
                     protein"
                     /protein_id="WP_147982567.1"
                     /sec_met_domain="Linocin_M18 (E-value: 9e-89, bitscore:
                     290.8, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNLHRELAPVTDSAWEQIEEEARRTFSRHVAGRRVVDVSDPQGP
                     ELSAVGDGHLRDIDPPTPDVIARARTARPVIEWRVPFTVTRAAVDDVERGSEDSDWQPV
                     KDAARTCAFAEDMAIIDGYAAAGITGLRDGSSHAPLPLPADARDYPTAVSQALTRLRLA
                     GVDGPYRLLLGADAYTEATETSDHGYPVATHLARQLDEPILWAPAVAGGLLLSTRGGDF
                     ELCLGQDLSTGYLDHDATSIRLYFHQAFTFRMLTPEAVVPLIA"
     gene            5709..>6074
                     /locus_tag="EAO74_RS38100"
                     /old_locus_tag="EAO74_03040"
                     /pseudo=""
     CDS             5709..>6074
                     /GO_function="GO:0008233 - peptidase activity [Evidence
                     IEA]"
                     /GO_process="GO:0042742 - defense response to bacterium
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Linocin_M18"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF016349.5"
                     /locus_tag="EAO74_RS38100"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03040"
                     /product="encapsulin"
                     /pseudo=""
                     /sec_met_domain="Linocin_M18 (E-value: 1.4e-19, bitscore:
                     64.1, seeds: 61, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPAEGASGLLLDLLPGGIGDGGEFAVQVVHRGALSCRLPIRSEPS
                     RTTGAXXXVERXSEDSDWQPVKDAARTCAFAEDMAIIDGYAAAGITGLRDGSSHAPLPL
                     PADARDYPTAVSQALTRL"
     gene            complement(5977..7074)
                     /locus_tag="EAO74_RS03045"
                     /old_locus_tag="EAO74_03045"
     CDS             complement(5977..7074)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014669185.1"
                     /locus_tag="EAO74_RS03045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03045"
                     /product="Dyp-type peroxidase"
                     /protein_id="WP_147982569.1"
                     /transl_table=11
                     /translation="MSDAVPEPVVVQPVVAPLTSAAVVLVATIEPGGESAVREVLPDLA
                     AFARSIGFRVPSAGLACVTGFGSEAWDRLFAGPRPARLHPFQELRGPVHRAPATPGDLL
                     FHVRAERMDVCYEWASQLLGRLGGAVKVVDETHGFRYFDHRDLLGFVDGTENPVGDDAR
                     AAAIVGPEDPAFEGGSYVVVQKYLHDLAGWNRLSTEEQERVIGRTKFTDMELADDVKPA
                     DSHIALNTVTGDDGTERDILRANMPFGSFEQGEFGTYFIGYAADPSVTEQMLRNMFLGS
                     PPGTHDRILDFSTAVTGTLFHAPSADFLDAPPPRCTRPRRAAAGTARRPRRAAAGSAPG
                     SPPSGSPARPPAAAAGRARNRPAAP"
     gene            complement(7195..7827)
                     /locus_tag="EAO74_RS03050"
                     /old_locus_tag="EAO74_03050"
     CDS             complement(7195..7827)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1224: TetR family
                     transcriptional regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015580263.1"
                     /locus_tag="EAO74_RS03050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03050"
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="WP_261988118.1"
                     /transl_table=11
                     /translation="MAQAQEPPRAPGTRRRGAELEEAILRAAAEVLKESGVPALTMDEV
                     ARRAGTNKNALYRRWPNRVALGVAAYRRLAAAETVLPDTGSLRGDTLEMLRRANSTWSS
                     PYGEILRGLIAAAGSAPELLAELRDPAGESAHEAAWLTVLGRAVARGDAAPEALHPRVA
                     YTPMALLRNEYVMLGVPAVPDTVLVEIVDEVFLPLVRGRAPHEAAPR"
     gene            7973..9049
                     /locus_tag="EAO74_RS03055"
                     /old_locus_tag="EAO74_03055"
     CDS             7973..9049
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014049227.1"
                     /locus_tag="EAO74_RS03055"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03055"
                     /product="hypothetical protein"
                     /protein_id="WP_147982570.1"
                     /transl_table=11
                     /translation="MRTFGITYDTGFTTAGTAGGAGTTTREVFDPAVVRREMQIIRDDL
                     GCDAVRVTGGDRDRLETAARHADDAGLEVWYSPFTNGLTTGELLDFLTDSAERAERLRR
                     EGAEVVFLTGSEISLFTAGMLPGDTFEERAAVLTDPQRLRAALPGLPAQVNAFLGTAVA
                     AVRARFGGRVGYASLPFEGVDWALFDLVATDAGYRDAQTADRLADGLRALTAHGKPAAV
                     TEFGCTTYRGAADAGGRGDAVIAWNERARAVRFTTPVARDEQEQADYLRELIDTFDGSA
                     VDAAFVNTFARYDLPHAPADDDRDFDKASFGVVKVLDDGRTGTAYPGLPWEPKAAFHTL
                     AAYGRSRAEGVVRSPHSS"
     gene            complement(9148..10605)
                     /gene="gndA"
                     /locus_tag="EAO74_RS03060"
                     /old_locus_tag="EAO74_03060"
     CDS             complement(9148..10605)
                     /EC_number="1.1.1.44"
                     /GO_function="GO:0004616 - phosphogluconate dehydrogenase
                     (decarboxylating) activity [Evidence IEA]"
                     /GO_function="GO:0050661 - NADP binding [Evidence IEA]"
                     /GO_process="GO:0006098 - pentose-phosphate shunt [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="gndA"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1100: 3-hydroxyisobutyrate dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946749.1"
                     /locus_tag="EAO74_RS03060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="EAO74_03060"
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="WP_147982571.1"
                     /transl_table=11
                     /translation="MPTTPSSGPTAQIGVTGLAVMGSNLARNFARHGHTVAVHNRTAAR
                     TRSLVDTYGEEGTFVPAESAEEFVASLEKPRRIVIMVKAGEATDAVIEEFAALLEDGDV
                     LIDGGNAHFQDTRRREKALRERGIHFVGTGISGGEEGALNGPSMMPGGSVESYTSLGPL
                     LESIAAKADDGAPCCTHIGPDGAGHFVKMVHNGIEYADMQLIGEAYQLLRDVAGYSPAQ
                     IADVFRTWNTGRLDSYLIEITAEVLSHVDEATGKPFVDVVLDQAEQKGTGRWTVQIALD
                     LGVPVSGIAEAVFARSVSGHSDLRDASRHLTGPTPRTLGTDEAAAFADQVEQALYASKI
                     VAYTQGFHEIAAGSEQYDWNIDLGKVAAIWRGGCIIRAAFLDRITSAYEAQPHMPSLLA
                     DKSFAQEIAAAQDDWRSVIATAVTQGVPTPAFAATLAYYDSLRAERLPAALTQGQRDYF
                     GAHTYHRTDREGTFHTLWGGDRTEVES"
     misc_feature    complement(10609..10624)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 20.23"
                     /tool="antismash"
ORIGIN
        1 tgcccctgga cgtcgagtca cgggtggtgg tgatcgctca ttcgacgaag tcgaaacccg
       61 ccgcctccgc acggaccgcc tgccggatga gttcacgcgg gccgaaggct tccgacgcca
      121 gtttgtagcc gatttccatg cgacgacctg acctcccgcg tgttcggagt tgggcgaacc
      181 tcaccgagcg agcttccgcc ttcatccgaa tggcggacct gccgacttca ctccccacgg
      241 gcagccccat ggtcaccgga cagtgcagca ccaggacgca taggcacacg cggcgacacg
      301 gcacgcatcg tgccccgccg tgatgttcct cgcgatggcg gcgagcgtga atgtcgccgc
      361 gagcgccgac gaattcaggc gcgacatccc ggagcgcgtc gcaggcctgc cgacacgctg
      421 acgtcggctg cgcagctgac acttcacgga catgtggccc ggaaccggct cgcgcccggt
      481 ggtgtcggtg cgccaggagc cgacggcctt ctcccgccac ctctgcctgg ccgcgaacgc
      541 ctcggcgccc acgcgtgccg tcggcgtaca cccgcaccgc cccttgatca gcctgcttcc
      601 gccagggctg cgcgcgcggc gtcaaggatc tctcgggaga gcggggagtc cttggtggcc
      661 cgggccagga ccagcgcacc gaacagggta cagaggcgga cgatgccgtc ctcgccatcg
      721 gtagcgagga agccggcgaa gtcggccacc ccctcggcgt aggcacgacg ggcctcgcta
      781 cccccgctct cgcgcgcgat gtccgtggcg agggctgcga ccggacagcc gtccgccggg
      841 tcgtcacggt gttcgacgga gaggtaggtg tcgatcagtg cctgctgggc ggccccgcgc
      901 tgcccgtcgt gccgttcgag cccagcgctg tagcgctggg cgagctcgga gaaggcatgg
      961 acggtcgcct cgtcgacgag cgcctccttg gaggcgaact gcttgtagaa cgcgccgtgg
     1021 gtcagaccgg ccgccttcat caggtcggcg acgctgacgt gcgtgccctg ctcccggaac
     1081 agccgggagg cggtgtccac cacccgcctg cgattttcct ccgcctgcgc ctgcgatacg
     1141 cggcccatgg ccacctccca cttggatgtc gactggcatc tatcgtagac ccatgtttag
     1201 attggaagcg taatctaaat gtgtgcgggt gccgacggtg cccgccagga cgaggagcga
     1261 gcatggaact gaagaacacg gtcgcggtcg tcaccggcgc caaccgaggc ctcgggcgac
     1321 acctcgcagc ccagctcgtc gagcgcggcg cgaaggtcta cgcggcggcc cgccgtcccg
     1381 agacggtcga cctgccggac gtcacgccgc tgcgcctcga cgtcacggac catgagtcga
     1441 tacgggaggc cgcccgcgtg gcatccgacg cgacactgct gatcaacaac gcgggcatct
     1501 ccacaggcgc gacgctggtc ggaggcggcc tggacgaggt acgtcgcgag atggagacca
     1561 acttcttcgg cccgctcgtc gcgacccgcg ccttcgcccc tgtcatcgag ggcaacggcg
     1621 gcggtgccgt actcaacgtc ctgtccgccc tgtcgtggtt ccacccggcc gccctcggct
     1681 cctacgcggc ctccaaggcc gcggcttggg cgctgagcga cgcgacccgt gaggagctgg
     1741 cgccgcgcgg gatcaccgtc tcggcgctgc acgtcggcta catggacacc gacatggccg
     1801 ccggcgtgcc cgccgatcag aaggtcgctg ccgccgacgt cgcggcccag gccctggacg
     1861 gggtcgaggc cggcctgccc gagatgctcg ccgatgaggc cagccggtac gtcaagcaga
     1921 gcctgtccgc agcaccccag ccgaccgagg gctgacgctc gcccctccac cccgacgcga
     1981 ccgccttccc gcccctggat gaagcacccg ccttgtcctc gttgccatcg gggcatcggc
     2041 ctgcgcgcgc tggtccagcc cgaagttgat gatcatcgga ccgtcatcgc ccagggtgtc
     2101 gttctgcggc ttcaggtctc gatggagcca ccccgctgcg tggactgctg acaagccttc
     2161 ggcgagcaac gtcccgaggc cggccgccag cggcagtgga agtgcaccat cgctgtccgc
     2221 gcaggccggc agcgtgtgac cggccacgta ctccatggca gccgcgtacg gggtgtcaga
     2281 atagtcagcg agtggtcagc atgagccctg aagaacctgg gggcagctcc ctggacctgc
     2341 gactcgttgt agagtgtgga aacagcactt gacctgcaaa aacgcaggca gggagcctag
     2401 cccgggagta tctccatgat gcgtacgatg ttcaagtcca agatccaccg agccaccgtg
     2461 acccaggccg acctgcacta tgtcggctcc gtgacgatcg acgccgatct gatggacgcc
     2521 gccgacctgc tgcccggcga gctcgtgcat atcgtggaca tcgacaacgg cgcccgcctg
     2581 gagacgtacg tcatcgcagg cgaacgcggt tccggcgtca tcgggatcaa cggcgccgcc
     2641 gctcacctcg tgcaccccgg tgacctggtc attctcatca gttacgccca ggtcgacgac
     2701 gccgaggcgc gtgccctcgt gccgagtgtc gtgcacgtcg acgcggccaa ccgcatcgtg
     2761 gccgtgggtg ccgacgcatc ggagcccgtg ccgggctcgc gtacggagcg cagtccgcag
     2821 gccgttcccg cacagggctg atccagcccg gaagtttcgc cgtacgaagg agtcccgcca
     2881 tggcagagga gcgcaccgca gtggagatca gggacgaccg ggagcacggc aagctggtgg
     2941 ccctcgacga gggcggctcg gtcgcgggga ccatcgcgta cttcgtgatg tatcccgagc
     3001 ccggcgccct cgtcggcgtg cacaccgtcg tccggccgga gcacgagggc aagggagtcg
     3061 ccggcgccct cgcgcgggag ttctacgcgc tggcggcccg gcagggggtc cccgtcgtcc
     3121 cgctctgccc gtacctcgcc gcgtgggccg agcggcaccc cgagcaggcc ccgaaggccc
     3181 ccgacgagct ggtacgcggc gccgagcggc agctcgggtc gcatcccgag ctgttctgag
     3241 gcgcggcccg gggtctcccg ggccaggagt cacagcgcgt acgtatggac tcggcaggcg
     3301 agggaagccg cacggcccac gcggcgaggt acgggcagag cgggacgacg gggaccccct
     3361 gccgggccgc cagcgcgtag aactcccgcg cgagggcgcc ggcgactccc ttgccctcgt
     3421 gctccggccg gacgacggtg tgcacgccga cggcacgggg cccgccgccc gtgccgccgg
     3481 gccccgtgcc gcccggcccc gcgcccgacc cgatcccgca gccgccggac ccgaaccccg
     3541 aaccggtacc cgagccggag ccctcgcccc agccgacggg gtgacccgga gttcctacgg
     3601 ccggccgtgc agccctgtca gcgccccggc gtggcgcagc ccgctctccg cagccaccga
     3661 gtccagcgac tgcgcctcgc gcaccggggc gaagcgcagg ctgccggttt cccccgcgaa
     3721 gccgtacacg gccggccggg gcaggctgtt gtaggcccac ggggtggaga agtagtacgc
     3781 ccccgtgtcg tacaggacga cgaagtcgcc ctcccgtagc tcgggcagct cccgggcatg
     3841 ggccaccacg tcccccgcga agcagcacgg ccccgcgatg tcctgcacca tcggcggccc
     3901 gccgcggggg cggccttccc cgtcgaacgc gccgatccgc agcggccacg cgtcgggcat
     3961 gaagacggta cgggtggcga tctgggcccc cgcgtgggtg agcgcgatgc ggcgcccgcc
     4021 cgcgtccttc gtgtactcca cgcgcgcccc gatgaagccg ttcttggcga gcagggacct
     4081 gccgaactcg gtgaccaggt cgtagcgccc gtcgaagagg cccggagccg cggagcggag
     4141 cgccgccacg tactcggcga aggcggggcg ggtctcgtcg tcgtcgaagt tgaccggcag
     4201 tccgcccccg atgtcgatcc cggtgacccg gcgcgtgccc agcaccccgt tgatctcctc
     4261 ggcgagccgg tacgtctcgg cgattcccgc ggcgatgagg tccagcgagc acccttgcga
     4321 gccgacatgg gcgtgcagcc gggtcagcca gggacgctcc acgaaggtct ggacgacccg
     4381 gtcgcgggcg ccggggtcgc gcagggccac cccgaacttc gaggtggctg tcgccgtgct
     4441 catggcgccg atggaaccgc cccccacctg cggattcacc cgcagcccca ggacggaggc
     4501 cgagccgggc gagcggagtc cctcgatacg gcggatctcg ccgaagctgt ccgcgttcac
     4561 ggcgacaccg agcgccagag ccagccggag ctcgtcccgg gtcttggcgg gggagtccag
     4621 gacgatccgt gccggggcga agccggcctc gaccgcgagc ctcagctcgc ccgggccggc
     4681 cacctcgcac cccatgccgc agtcggccag cagccgcagg accgggatca gcgacgcggc
     4741 cttcgcggcg aaggtgtgca gcacccgcac gcccggttcg gcggcgaacg cgtcgcgcag
     4801 cgcgtcggca ctctcgcgga tcccgtccgc gtccagaaag cccgcgaggg ggcgctcctc
     4861 gcccagcagc ccttccgcca ccgcgaggcg cagcacctcg gcgaaccggg cggagcgcgg
     4921 tgggcggccg gaagggggcg cgggaccggg tggcggtgtg gggctggtgg cgtcgatggg
     4981 agcctcgcag gtcggtgcct tcaggcgatg agcgggacca cggcctcggg cgtcagcatc
     5041 cggaaggtga acgcctggtg gaagtagagc ctgatgctgg tcgcgtcgtg gtccagatac
     5101 ccggtggaca ggtcctggcc caggcacagc tcgaagtcgc cgccacgggt ggacagcagg
     5161 agccctccgg cgacggcggg cgcccacagg atgggctcgt cgagctgccg tgccagatgg
     5221 gtggccaccg gataaccgtg gtcggaggtc tcggtggcct cggtgtacgc gtccgcgccg
     5281 agcagcagcc ggtacggccc gtcgaccccg gcgagccgca gccgggtcag cgcctggctc
     5341 accgccgtcg ggtagtcccg cgcgtccgcc ggcagcggca gcggggcgtg cgaggaaccg
     5401 tcccgcagcc ccgtgatgcc ggccgccgcg tacccgtcga tgatcgccat gtcctcggcg
     5461 aacgcacagg tgcgggcggc gtccttgacc ggctgccagt cgctgtcctc ggagccgcgc
     5521 tccacgtcgt cgacggcggc ccgggtcacc gtgaacggca cccgccactc gatgaccggc
     5581 cgcgccgtgc gggcccgggc gatcacatca ggggtgggag ggtcgatgtc gcgcagatgc
     5641 ccgtcgccga cagccgacag ctccgggccc tgcgggtcgc tgacgtcgac gacccggcgg
     5701 cccgccacat gccggctgaa ggtgcgtctg gcctcctcct cgatctgctc ccaggcggaa
     5761 tcggtgacgg gggcgagttc gcggtgcagg ttgttcatcg cggggcgctt tcttgcaggc
     5821 tgccgatacg cagcgaaccg tcgcggacca ccggcgccgn cgnngncgtg gagcgcngct
     5881 ccgaggacag cgactggcag ccggtcaagg acgccgcccg cacctgtgcg ttcgccgagg
     5941 acatggcgat catcgacggg tacgcggcgg ccggcatcac ggggctgcgg gacggttcct
     6001 cgcacgcccc gctgccgctg ccggcggacg cgcgggacta cccgacggcg gtgagccagg
     6061 cgctgacccg gctgcggctc gccggggtcg acgggccgta ccggctgctg ctcggcgcgg
     6121 acgcgtacac cggggcggag gggcatcgag gaagtcggcg ctgggggcgt ggaagagcgt
     6181 gccggtgacc gccgtggaga agtcgaggat gcggtcgtgg gtcccgggcg ggctccccag
     6241 gaacatgttg cggagcatct gttcggtgac cgacggatcg gccgcgtacc cgatgaagta
     6301 cgttccgaac tcgccttgtt cgaagctgcc gaagggcatg ttggcgcgca ggatgtcgcg
     6361 ttcggtgccg tcgtcgccgg tgacggtgtt cagggcgatg tgcgaatcgg ccggcttgac
     6421 gtcgtcggcg agctccatgt ccgtgaactt cgtacggccg atgacccgtt cctgctcctc
     6481 ggtgctcagc ctgttccagc ccgccaggtc gtgcaggtac ttctgcacca cgacgtagct
     6541 gccgccctcg aaggccgggt cctccggacc gacgatggcc gcggccctcg cgtcgtcgcc
     6601 caccgggttc tccgtaccgt cgacgaaacc gagcaggtcc cggtggtcga aatagcggaa
     6661 tccgtgggtc tcgtcgacca ccttcaccgc accgccgagc cgtccgagga gctgggaggc
     6721 ccactcgtag cagacgtcca tccgttcggc gcgcacatgg aacagcaggt cgcccggtgt
     6781 ggccggggcg cggtggacgg ggccccggag ctcctggaag gggtggagac gggccggccg
     6841 cggacccgcg aacagccggt cccacgcctc ggagccgaag cccgtcacac aggcgagccc
     6901 ggcgctcggc acccggaagc cgatcgaccg cgcgaacgcg gcgagatcgg gcagcacctc
     6961 gcgcacggcc gactcgccgc ccggctcgat cgtcgcgacc agcaccaccg cggcgctggt
     7021 cagcggtgcc acgacgggct ggaccacaac gggctccggt acggcgtcgg acatgcgcgc
     7081 actccgtggg tggtggacag ggctccctgc cacttatcca catgtcgccc ccggccgcac
     7141 cccggcccgg cccggccggg cgacgtacgg cctgtcgtgc cggccttcac ggaatcagcg
     7201 gggtgccgcc tcgtgcgggg cccgtccgcg aaccaggggc aggaagacct cgtcgacgat
     7261 ctcgacgagg acggtgtcgg gcacggccgg gacgccgagc atcacgtact cgttgcgcag
     7321 cagcgccatg ggcgtgtacg cgacccgggg gtgcagcgcc tcgggggcgg cgtcaccacg
     7381 ggccaccgcc cggcccagca cggtcagcca ggccgcctcg tgcgcgctct cgccggccgg
     7441 gtcgcgcagc tcggccagca gctccggagc gctgcccgcc gcagcgatca ggccgcgcag
     7501 gatctccccg tacggcgacg accaggtgct gttcgcgcgg cgcagcatct ccagggtgtc
     7561 cccgcgcaag gagccggtgt cgggcagcac ggtctccgcc gcggccagcc gacggtacgc
     7621 cgccacgccg agggcgacgc ggttgggcca acgccggtac agcgcgttct tgttggtccc
     7681 ggcccgccgg gccacctcgt ccatcgtcag ggccgggacg ccggactcct tcagcacctc
     7741 ggcggcggcc cgcaggatgg cctcctccag ttcggccccc cgtcgccgcg tccccggggc
     7801 ccgcggcggt tcctgcgctt gtgccaccgg ctgattcctc tcgctccacg gatccacggc
     7861 acgcatcgta cgttccggta tcgcgacgag tcccatgtcg aacttcgttc agggtacggt
     7921 gcgtaccgta taaggtacgt cgcgtacctt gaatcgtgag gagagcacct tcatgcgcac
     7981 cttcggcatc acgtacgaca ccggcttcac cactgcggga accgcaggag gcgcgggaac
     8041 caccacccgt gaggtcttcg accccgcagt cgtccgccgc gagatgcaga tcatccgcga
     8101 cgatctgggc tgtgacgccg tgcgcgtcac cggcggcgac cgcgaccggc tcgagacggc
     8161 cgcgcgccat gcggacgacg ccggactgga ggtgtggtac tcgccgttca ccaacggact
     8221 caccaccgga gagctcctcg acttcctcac cgacagcgcc gaacgcgccg aacggctgcg
     8281 ccgtgagggc gccgaggtcg tcttcctcac cggctcggag atctccctct tcaccgccgg
     8341 catgctcccc ggcgacacct tcgaggaacg cgccgccgtc ctcaccgacc cgcagcggct
     8401 gcgggccgcg ctgccggggc tccccgccca ggtcaacgcc ttcctcggca cggcggtcgc
     8461 cgcggtgcgg gcccggttcg gcggccgggt cgggtacgcc tcactcccgt tcgagggcgt
     8521 cgactgggcg ctgttcgacc tggtcgccac cgacgccggc taccgcgacg cgcagaccgc
     8581 cgaccggctc gccgacggac tacgggcact gaccgcacac ggaaagccgg ccgccgtcac
     8641 cgagttcggc tgcaccacct accgcggggc cgccgacgcc ggcggccggg gggacgccgt
     8701 catcgcgtgg aacgagcgcg cccgtgcggt gcggttcacc acgcccgtcg cacgggacga
     8761 acaggagcaa gccgactacc tgcgggaact catcgacacc ttcgacgggt ccgccgtcga
     8821 cgcggccttc gtgaacacct tcgcccgcta cgacctcccg cacgcgcccg ccgacgacga
     8881 ccgggacttc gacaaagcgt cgttcggcgt ggtcaaggtc ctcgacgacg gccgcaccgg
     8941 taccgcgtac ccgggcctgc catgggagcc caaagcggcc ttccacacgc tcgcggcgta
     9001 cggccggagc cgggcagagg gggtggtgcg ctcaccccac tcctcgtagg aggtcaccac
     9061 gaggggctgc gtaccacggt cgcgggcaga gcatgggccg ggcacgagtg ccggagcggg
     9121 gcgcaggcac ctttgccccg gtgtcggtca gctctcgacc tcggtcctgt cgccgcccca
     9181 gagggtgtgg aacgtgccct cgcggtcggt gcggtggtag gtgtgtgcgc cgaagtagtc
     9241 gcgctggccc tgggtgaggg cggcggggag gcgttcggcg cgcagggagt cgtagtaggc
     9301 gagggtggcg gcgaaggcag gggtggggac gccctgggtg acggcggtgg cgatcacgga
     9361 gcgccagtcg tcctgggcgg cggcgatctc ctgcgcgaag ctcttgtcgg cgaggaggct
     9421 cggcatgtgg ggctgggcct cgtaggcgct ggtgatcctg tcgaggaacg cggcgcggat
     9481 gatgcatccg ccgcgccaga tcgcggcgac cttgccgagg tcgatgttcc agtcgtactg
     9541 ctcgctgccg gccgcgatct cgtggaagcc ctgggtgtag gcgacgatct tcgaggcgta
     9601 cagggcctgt tcgacctggt cggcgaaggc tgccgcctcg tccgtgccga gtgtgcgggg
     9661 ggtcggtccg gtcaggtggc gtgaggcgtc gcggaggtcg gagtggccgg agacggagcg
     9721 ggcgaagacg gcctcggcga tgccggagac ggggacgccc aggtcgaggg cgatctgcac
     9781 ggtccaccgg ccggtcccct tctgctcggc ctggtcgagc accacgtcca cgaagggctt
     9841 cccggtcgcc tcgtcgacgt gcgagaggac ctcggcggtg atctcgatga ggtaggagtc
     9901 caggcgcccg gtgttccagg tgcggaagac gtccgcgatc tgcgcggggg agtagccggc
     9961 gacgtcacgg agcagctggt acgcctcgcc gatgagctgc atgtcggcgt actcgatgcc
    10021 gttgtgcacc atcttcacga agtgcccggc gccgtccggc ccgatgtggg tgcagcaggg
    10081 cgccccgtcg tccgccttgg cggcgatgct ctcgaggaga ggccccagcg aggtgtacga
    10141 ctccaccgat ccgccgggca tcatgctcgg cccgttcagc gccccctcct cgcccccgga
    10201 gatgccggtg ccgacgaagt ggatgccccg ctcccgcagc gccttctcgc ggcgccgggt
    10261 gtcctggaag tgtgcgttgc cgccgtcgat gaggacgtcg ccgtcctcca gaagcgcggc
    10321 gaactcctcg atgacggcgt ccgtcgcctc accggccttg accatgatga cgatacggcg
    10381 cggcttctcg agggaggcga cgaactcctc ggcgctctcg gcggggacga aggtcccctc
    10441 ctcgccgtac gtgtcgacga gagacctggt gcgggccgcg gtgcggttgt ggacggcgac
    10501 ggtgtggccg tgacgggcga agttacgggc gagattgctg cccatgacgg cgagtccggt
    10561 gacgccgatc tgagcggtgg gtccggacga gggggtggtg ggcatggcgg tggtccactc
    10621 ctgttgcgat cgacgagctc ttgcaccggg ggcccgtgcc ggggacggac gggcggcgcc
    10681 cgggccggta tccgtacgca gcccggccat gttcgcatgc ccggcccggg tgagcccgat
    10741 gcgcgcgggg agtgggcagg ggcgtgtcac accgccgcgc cgtgcggtgc ggcacgcccc
    10801 cgggacctgg tcagcggccg ggcgcaccgc ggcgacgcgt ggacgtgtag agcgtgggat
    10861 gcgcccttcc ctcggtcgcg tacgggcgtg gggcgaccgt ggagccggtg acctggaagt
    10921 actccccgcc gaaggtgacg tcctcctcgg tccacagccg ccgcgggaga taaaggaact
    10981 cctgggtgcg ggcgtaccgt cgggccgggt cgacgttcgt gtccccgtac gcgtccaggt
    11041 tgtccagccc gctgacgatg ttgaacagga cccg
//
