LOCUS       NZ_CP042828            12835 bp    DNA     circular CON 27-APR-2024
DEFINITION  Ruania zhangjianzhongii strain HY168 chromosome, complete genome.
ACCESSION   NZ_CP042828
VERSION     NZ_CP042828.1
KEYWORDS    RefSeq.
SOURCE      Ruania zhangjianzhongii
  ORGANISM  Ruania zhangjianzhongii
            Bacteria; Actinomycetota; Actinomycetes; Micrococcales; Ruaniaceae;
            Ruania.
REFERENCE   1  (bases 1 to 5067305)
  AUTHORS   Huang,Y.
  TITLE     Ruania sp. HY168
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5067305)
  AUTHORS   Huang,Y.
  TITLE     Direct Submission
  JOURNAL   Submitted (12-AUG-2019) National Institute for Communicable Disease
            Control and Prevention, Chinese Center for Disease Control and
            Prevention, Changping, Beijing 102206, China
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Method                   :: HGAP v. HGAP 3.0
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 178.0x
            Sequencing Technology             :: PacBio
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_008000995.1-RS_2024_04_27
            Annotation Date                   :: 04/27/2024 03:28:42
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.7
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 4,709
            CDSs (total)                      :: 4,654
            Genes (coding)                    :: 4,621
            CDSs (with protein)               :: 4,621
            Genes (RNA)                       :: 55
            rRNAs                             :: 2, 2, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2, 2, 2 (5S, 16S, 23S)
            tRNAs                             :: 46
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 33
            CDSs (without protein)            :: 33
            Pseudo Genes (ambiguous residues) :: 0 of 33
            Pseudo Genes (frameshifted)       :: 13 of 33
            Pseudo Genes (incomplete)         :: 20 of 33
            Pseudo Genes (internal stop)      :: 1 of 33
            Pseudo Genes (multiple problems)  :: 1 of 33
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 07:19:52
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 2458767
            Orig. end                         :: 2471602
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            CP042828.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     region          1..12835
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="hydrogen-cyanide"
                     /region_number="4"
                     /rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD) and DAO)"
                     /tool="antismash"
     cand_cluster    1..12835
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /kind="single"
                     /product="hydrogen-cyanide"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..12835
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:7835](-)"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(5001..7835)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(Fer2_4 and cds(Pyr_redox_2 and Fer2_BFD)
                     and DAO)"
                     /neighbourhood="5000"
                     /product="hydrogen-cyanide"
                     /protocluster_number="1"
     gene            80..1378
                     /locus_tag="FU260_RS11410"
     CDS             80..1378
                     /GO_function="GO:0016773 - phosphotransferase activity,
                     alcohol group as acceptor [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF016472.4"
                     /locus_tag="FU260_RS11410"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="ADP-dependent glucokinase/phosphofructokinase"
                     /protein_id="WP_147917174.1"
                     /transl_table=11
                     /translation="MTETSYRAARTVHEWAGFYHALVVRRSALVAGAGPIVTGFSATTD
                     ALHRITGASLTRLLTAGPSGSEIFDAGLGTLGGWLAEGRDGELFIDDVGGEPLLEALVG
                     MAEKVQCGGTSVQASWSWSQLGLHPLLALLNRNPRQLGATPAGVRLATADGGVPVHSIT
                     PVAGMSVPSNHVLELSAGLTGAGVQVQRSSRITVVFARKRLQLDEAFLRISPSAVRGGV
                     GMVSGLNGLGRAREKVLPIVADTVAAWNDGGARLVHLELAEYASPGELAQVMTAVGPHV
                     HSVGMNASELERLVGGGDPAQRAAEFAAAHGLLRVVVHGDHWAMSVHRADPEREELALG
                     AGSLAAANRAANGEPQAEWAVPVRARFSSELPVAGRLDGGYRMTIVATPYLTTPRSTIG
                     LGDTFVSGDLLVQANPLDLNRHRRTLSWNTRRP"
     gene            1357..2115
                     /locus_tag="FU260_RS11415"
     CDS             1357..2115
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (11-181). E-value: 4.8e-11.
                     Score: 34.8. Matches aSDomain:
                     nrpspksdomains_FU260_RS11415_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010203356.1"
                     /locus_tag="FU260_RS11415"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="SDR family oxidoreductase"
                     /protein_id="WP_147917175.1"
                     /sec_met_domain="adh_short (E-value: 3.1e-34, bitscore:
                     116.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEHPQTLTGRRVIVTGGGVGIGLGIVRQFAAAGAQVALTTHSRAA
                     TDVVQTLAGGGLTVIGAQLDATDSAQVNTVVDDLAANLGGLDVVVNNAGGLVGRHTFAE
                     TSDEHWATVWSVNVTSAFYVSRAGLRHLGEGGRIINISSLAGENGGGNGSGPYATSKAA
                     VDGLTRALAKEVAPAGITVNSIAPGLILDTPFHETFTPKAAQQQTIAGIPVGRPGYPAD
                     VATAAEYFARLDSGFVTGTVLDLNGGVHFS"
     aSDomain        1390..1899
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FU260_RS11415_PKS_KR.1"
                     /evalue="4.80E-11"
                     /label="FU260_RS11415_PKS_KR.1"
                     /locus_tag="FU260_RS11415"
                     /protein_end="181"
                     /protein_start="11"
                     /score="34.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VIVTGGGVGIGLGIVRQFAAAGAQVALTTHSRAATDVVQTLAGGG
                     LTVIGAQLDATDSAQVNTVVDDLAANLGGLDVVVNNAGGLVGRHTFAETSDEHWATVWS
                     VNVTSAFYVSRAGLRHLGEGGRIINISSLAGENGGGNGSGPYATSKAAVDGLTRALAKE
                     VAPAGIT"
     CDS_motif       1393..1461
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FU260_RS11415_0001"
                     /evalue="4.00E-02"
                     /label="PKSI-KR_m1"
                     /locus_tag="FU260_RS11415"
                     /protein_end="35"
                     /protein_start="12"
                     /score="6.7"
                     /tool="antismash"
                     /translation="IVTGGGVGIGLGIVRQFAAAGAQ"
     gene            complement(2167..3114)
                     /locus_tag="FU260_RS11420"
     CDS             complement(2167..3114)
                     /codon_start=1
                     /inference="COORDINATES: ab initio prediction:GeneMarkS-2+"
                     /locus_tag="FU260_RS11420"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /product="hypothetical protein"
                     /protein_id="WP_147917176.1"
                     /transl_table=11
                     /translation="MEITRRSALILAAGVGLATVPAGSAQAAYYNDYETIARIPNAHGC
                     TAAQGFAAGGTYLYSVKIRSDDARAIIYRTNRTSGATEIMTNGTDGVAYNSWLGHANDM
                     TLATIDGEYYMFIVTMTTEGAQLVKLKYVSKTYYKVGTFAIHLGGTAKAVSGITRTAKT
                     STRIDFLFKSVLNVYRGSIGLRDDSGTIDITEAFTLDTAGAKVDGEVVPDIGDFTNQGF
                     FYDENVKDLFHPLTKGNRSIVLHYPNVTDETSGAITPDPERSFRVTSSTYPRLFEIESL
                     GISDGTLYFSTNRSKSASDADWDGVHSFKGFSRS"
     gene            complement(3196..4590)
                     /gene="hydA"
                     /locus_tag="FU260_RS11425"
     CDS             complement(3196..4590)
                     /EC_number="3.5.2.2"
                     /GO_function="GO:0004157 - dihydropyrimidinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /gene="hydA"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:TIGR02033.1"
                     /locus_tag="FU260_RS11425"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydropyrimidinase"
                     /protein_id="WP_210418257.1"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.6e-22, bitscore:
                     76.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRPDLVVRGGEVVNADSIVRADICVSQGRVTALTEPGHAPSGND
                     EVDATGMLVLPGGVDPHCHVGFTSGEFTTLDDYPAATRAAVHGGTTTIVDFGIPTRGER
                     VVDAVHRQRAQATQGFCDSALHACVVDWDESTGAQLDQLVGEGVVTVKLFTTYRDETMA
                     NEETILRTMKHLSPLGGMVYVHCEANTIVEDTQDQVARSGDISAGHHHETRPELAESAA
                     VAAVLALAEHAGAPVYFVHQSTPEAVALVEHARSEGRQAYGEAVVHHLTLDESEYSAEH
                     PERFVCCPPLRSARTVQGLRSKLLTGGVSTIGSDHCCYDTEQKLLTKHDVRSMPNGLPG
                     VETRLPVAFSEFVSSGLMPVTQFVDLTATTPARLNGLYPRKGLIAPGSDADLAIWDPEA
                     TATVGTSTLHMATDYTPYEGREIRGLPVTVLVRGEAVVRDRDFVATGAHGQFVPATPLW
                     DVVRAG"
     gene            complement(4587..4979)
                     /locus_tag="FU260_RS11430"
     CDS             complement(4587..4979)
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF017868.4"
                     /locus_tag="FU260_RS11430"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="WP_147917177.1"
                     /transl_table=11
                     /translation="MELVKMFVNGQAMSGGSISSGLRNARFLGAATTAAAYRFYSVRAE
                     FPGLSWAERGGSSIAGELYEVSYAALRSELLPLEPPELELSIIELEDGTGSLSMVMRTE
                     AIEAEGTVEITEHGGWRAYLAERENA"
     gene            complement(5001..6161)
                     /locus_tag="FU260_RS11435"
     CDS             complement(5001..6161)
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1103: FAD dependent oxidoreductase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF013434.4"
                     /locus_tag="FU260_RS11435"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="FAD-binding oxidoreductase"
                     /protein_id="WP_210418258.1"
                     /sec_met_domain="DAO (E-value: 6.1e-52, bitscore: 175.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTDVVVIGGGILGASAAYQLARAGHQVTVLERGAPNREGSGTT
                     AGNLHIQGIHTKRPGQAVAADNLRFLPLQRTASAMWSALPDELDADIELTRNGGFMVAE
                     TPDQVAELHAKLAVELELGLSCEIVSGDEARSRMPALSESVIAAEWCAEDGYANPLLVT
                     PAYLAAARRHGAQVEAFSPVTAIERDGGAYVVRSSHRAWSAAAVIDTAGPWIADVAALA
                     GIALDMSPVAIQMHITTRMPPRTLSCLVQHIGAGMSVKQVTAGNILIGGGWPATEFRSE
                     GRSRVATESISGNLHQAAAILPVLRELRLLRTWAGPLAATPDEMPVIGEVPSSPGFFVA
                     GGTYAFTLAPLWGHVLRDLVEGNRPAEPVADLGVDRLELEAVAHQR"
     gene            complement(6158..7564)
                     /locus_tag="FU260_RS11440"
     CDS             complement(6158..7564)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Pyr_redox_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_BFD"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: DAO"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1176: alkyl hydroperoxide reductase subunit"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF019604.4"
                     /locus_tag="FU260_RS11440"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="WP_147917178.1"
                     /sec_met_domain="Pyr_redox_2 (E-value: 1e-24, bitscore:
                     85.4, seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="DAO (E-value: 7.7e-08, bitscore: 30.4,
                     seeds: 521, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_BFD (E-value: 5.9e-10, bitscore:
                     37.5, seeds: 211, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTTDPQPAAAPSHLDYDVVVVGGGPSGLVTARELATAGARVALI
                     EESAELGGQYYKRRRGQVLARHGDFRPAGTALIAQVRQAGVQVHTNRLVWGTTPDRALL
                     TTSTTSPDAVRFTARAIVVGTGATEHVLPFPGWQLPGVITPGHAMHLATTDVVRVGQRV
                     LIAGSGPFLLPVACAVLASGSEVAAVVEAGRPLRPSARALGAAAHPGMLGELARYLTVL
                     ARHRVPILQGAHVSESTAGPDGRLRTVSIATTTGNRSFDVDTLATAVRFRPATELLQLL
                     EVECSLDPELGVPIPDTDARGATSAPGVYAVGEARGIAGSKGAQVRGWLAAATIREELG
                     LSAPPERAVRRYERRSRRLDDFSRLTSDLYAHDREPMLAMPDHTMVCRCESVTAGEIRT
                     AARLGWNDRNGVKGATRAGMGPCQGRECASTVSCLVSACTGEPVGCQPARMPVKPIPVR
                     AAMAMEERQL"
     gene            complement(7551..7835)
                     /locus_tag="FU260_RS11445"
     CDS             complement(7551..7835)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     hydrogen-cyanide: Fer2_4"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: protein motif:HMM:NF024900.4"
                     /locus_tag="FU260_RS11445"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="(2Fe-2S)-binding protein"
                     /protein_id="WP_147917179.1"
                     /sec_met_domain="Fer2_4 (E-value: 1e-23, bitscore: 81.3,
                     seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRSNDAAPLTITVDGDPLRALAGQSVAGAMEAAGIRTWRSNPVD
                     GSPRAPFCGMGVCYECELHVDGSAETRACMVEVERGLVVRTEGVGRVHD"
     gene            complement(7832..8635)
                     /locus_tag="FU260_RS11450"
     CDS             complement(7832..8635)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013837337.1"
                     /locus_tag="FU260_RS11450"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="WP_147917180.1"
                     /transl_table=11
                     /translation="MSTLATPPHTSKPTTEIVARVHKVNKSFGSLHVLKDIDLEIHKGE
                     VVLLLGPSGSGKSTLLRTLNVLETIDSGEITISDELMGQRRTGKGLRPLRESRIAEQRR
                     RTGMVFQQFNLFPNMTALENVASGPIHVAGKSKQKSAAAAKELLAMVGLPDKGANYPSH
                     LSGGQQQRVAIARALAMRPDIMLFDEPTSALDPEMVKEVLETLINLRKDGMTMIVVSHE
                     MAFARAAADRVIFMDDGEIVEQASPAEFFDNPKTERARKFLGQLV"
     gene            complement(8632..9375)
                     /locus_tag="FU260_RS11455"
     CDS             complement(8632..9375)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /GO_process="GO:0006865 - amino acid transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1096: polar amino
                     acid ABC transporter, inner membrane"
                     /gene_kind="transport"
                     /inference="COORDINATES: protein motif:HMM:NF012738.4"
                     /locus_tag="FU260_RS11455"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="amino acid ABC transporter permease"
                     /protein_id="WP_210418259.1"
                     /transl_table=11
                     /translation="MRTPDMWSWDAFLTYLTAETLLQGAVTTIWLTVVTMVLGLILGLV
                     LAIARGSRVLPLRWFGNFYIWLFRGTPVLVQLIIIYTGLPQLGLKLSPVWCAIIGLSLN
                     EAAYLSEIVRGGIMSVAKGQYEAARALGMSPIKVMRVVVLPQAFRIMVPPLGNSLNGML
                     KTTTLVSVISVEELLRRTQYAVQVDFRVLEGLVAAALYFLLMTSIWTLIQSRIESVLNK
                     SHRAAPNQSEARELQLESELEGVSR"
     gene            complement(9362..10237)
                     /locus_tag="FU260_RS11460"
     CDS             complement(9362..10237)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1091: glutamine-binding lipoprotein glnH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: protein motif:HMM:NF012707.4"
                     /locus_tag="FU260_RS11460"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="WP_147917181.1"
                     /transl_table=11
                     /translation="MRTTRLLPVGAAIGALVLASCSGGGEDEPDLSGCEPAVSDDLLIT
                     PGTLTFSTNATLPPMQYVDGDEVVGMRVELVTEIATRLCLETEVMNVPFDAQIPGVQGD
                     RWDLINTGMFYTEERAETLDLVPYEVQAVAISVQDGEAEGIETVEDLAGLTIGVEAPGY
                     EFDSVNAVNDEIVDAGLDPLDINTSLTNADAFQALSAGQIDGVAIVEAVTSFYEEDGRF
                     TTAISGLHPGPLAFGFAKDNELADIVAETYGEMVDDGFVQELFDSYGVTPYPGPYEVTT
                     GPVELEGEDT"
     gene            complement(10240..11181)
                     /locus_tag="FU260_RS11465"
     CDS             complement(10240..11181)
                     /EC_number="4.1.3.3"
                     /EC_number="4.2.1.41"
                     /EC_number="4.3.3.7"
                     /GO_process="GO:0009436 - glyoxylate catabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0071704 - organic substance metabolic
                     process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF012904.4"
                     /locus_tag="FU260_RS11465"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="WP_147917182.1"
                     /transl_table=11
                     /translation="MQRSDVPWRGYWPAAPTPYTAGGQLDEDGLVRLLALYVDQGVHGV
                     LINGTTGEWFSQTRAERRRVAEIAVATVAGRIPVVIGCTTYTPGETIELAREVKAIGAD
                     GALATPPPYAHPSQDEIYAFYETVTNAVEIPWMAYNWPRGTAVDISVETASLLADLPHV
                     VAIKDSTGDELKCMETVEAVADRVRAFGRFIHPRGMAFMLGVGGDGNIDGGGLGAPFAV
                     PFYNEVFAGNLEAAREHGTRYARLVSVLVNNDYSSKFASPTSQLKAAMNLLGQPGGQVR
                     PPLLAMAEENSTDLAHALAEAGLSPHQPSHKE"
     misc_feature    11316..11330
                     /note="TFBS match to MexT, Global virulence regulator,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     gene            11320..12348
                     /locus_tag="FU260_RS11470"
     CDS             11320..12348
                     /GO_function="GO:0000976 - transcription cis-regulatory
                     region binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0006351 - DNA-templated transcription
                     [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /GO_process="GO:0045892 - negative regulation of
                     DNA-templated transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1078: LacI family
                     transcription regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: protein motif:HMM:NF012742.4"
                     /locus_tag="FU260_RS11470"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="WP_147917183.1"
                     /transl_table=11
                     /translation="MASIPKRRATLLDVAAAAGVSRSTASRVLSGEGAVSAGTEERVRA
                     AAAEVGYLLNSAARTLRTSRTMLTGLVLNNLVNATFHVVAEIVQQRLAQDGYRMILCVT
                     GGQAEEEAEYLTTLAEQGVDGIIVVGSGANIEQLNAIHRAGTGIVNLIRAGKGAPGDRV
                     LASDRDGAVLATEELLELGHRRIGYIGGPAQTNSGRERFQGYQNTMHAAGLFAEDLVLR
                     GPFSPDFGAEAIQQMLRVPEPPTAVYVANHEASFGALPTLRDLQVRLPADLSLIAHDEP
                     SWFQYWDPAVSIVDSGPVELAELAATRLIAAMRPGGLAERPREFRVGARLVTRGSSAAL
                     GS"
ORIGIN
        1 ggctggaggt cgccgagccc acgacgatcg gcctgggcga taccttcctc ggcggactcg
       61 tggccgggct ggtgcagtca tgaccgagac ttcctaccga gctgcgcgga cggtgcacga
      121 gtgggcgggg ttctatcacg cgctcgtggt ccgccgatcg gcgttggtgg ccggcgcggg
      181 cccgatcgtg accgggtttt ccgcgaccac cgatgccctg caccggatca ccggcgcctc
      241 gctcacgcgg ctgctcaccg cggggccgag cgggtccgag atcttcgatg cagggctggg
      301 gacgttgggg ggctggctgg cggagggacg cgacggtgag ttgttcatcg acgatgtggg
      361 cggcgaacca ctcctcgagg cgctggtcgg catggccgag aaggtgcagt gcggtggcac
      421 atcggtgcag gcgtcatgga gctggtccca gctggggctg caccccctgc tcgccctgct
      481 gaaccgcaac cctcggcagc tcggggccac tcccgcaggg gtgcgcttgg ccactgctga
      541 cggcggggtg ccggtgcaca gcatcactcc ggtggcgggc atgagcgtgc cgtcgaacca
      601 tgttctggag ctgtcggctg gcctcaccgg cgcaggggtc caggtacagc gttcgagtcg
      661 catcaccgtg gtcttcgccc gcaaacgcct ccagctggac gaggcatttc tcagaatctc
      721 gccgagcgcc gtacgcggtg gggtaggcat ggtgtccgga ctgaatggcc tcggccgtgc
      781 gcgcgagaaa gtattgccga tcgtggccga cacggtggcg gcgtggaacg atggcggtgc
      841 ccgcctggtg cacctggagc tcgccgagta cgcgagcccc ggcgagctgg cgcaggtgat
      901 gactgccgtg gggccgcacg tgcactcggt ggggatgaac gcgagcgagc tggagcggct
      961 cgtgggtggg ggagacccgg cacagcgcgc cgccgagttc gccgcggcgc acgggctgct
     1021 ccgggtggtg gtgcatggcg accactgggc aatgagcgtg caccgcgccg atcctgagcg
     1081 tgaggaactg gcgctgggtg cgggcagctt ggcggctgcc aaccgcgccg cgaacggtga
     1141 gccgcaggcc gaatgggccg tgcccgtgcg ggcgcgattc tcctcggagc tacccgtggc
     1201 cggtcgtctg gacggcggtt accggatgac catcgttgcc acgccctatc tgaccacgcc
     1261 gagatccacg atcgggctgg gggacacctt cgtcagcggt gacctgctgg tgcaggccaa
     1321 ccccctcgat ctgaaccgac acaggagaac actttcatgg aacacccgca gaccctgact
     1381 ggccgccgcg tgatcgtcac tgggggagga gtcggcatcg gcctgggcat cgttcggcag
     1441 tttgctgccg ccggtgcgca ggtggccctc accacccaca gccgcgccgc cacggacgtg
     1501 gtgcagacct tggccggtgg cggactgacg gtgatcggtg ctcagcttga cgccaccgac
     1561 agtgctcagg tgaacacggt ggtcgacgat ctggcagcga atcttggcgg gctcgacgtg
     1621 gtggtgaaca acgccggcgg actggtcggc cggcacacgt tcgcagagac cagcgatgag
     1681 cactgggcca cggtgtggag cgtgaacgtg acctcggcgt tctacgtctc ccgcgccggg
     1741 ctgcggcacc tgggcgaggg cggccggatc atcaacatct cctcgctggc cggggagaac
     1801 gggggcggaa acggctcggg cccctatgcc acctcgaagg ctgcggtgga cgggctgacc
     1861 cgtgcactgg cgaaggaagt ggcgccggcg ggcatcacgg tgaattccat cgcgccgggg
     1921 ctgatcctgg acacgccgtt ccacgagacc ttcaccccca aggctgccca gcagcagacc
     1981 atcgccggga tcccggtggg ccggcccggc tatccggccg acgtggcaac ggccgcggag
     2041 tactttgcgc ggctcgactc gggcttcgtg accggtacgg tgctggacct gaacggggga
     2101 gtgcacttct cctgaggtgc cggagggccg tgtgtcgggc cctggcaacg aatgggcgcc
     2161 tcggccctag ctccggctga accccttgaa ggagtgcaca ccgtcccagt cggcgtccga
     2221 ggccgacttg gatcggttgg tgctgaagta cagggtgccg tcgctgatcc cgaggctctc
     2281 gatctcgaac aggcgtggat acgtcgagga cgtcacccgg aaggaccgtt cagggtccgg
     2341 ggtgatcgcg cctgaggtct cgtccgtcac gttcgggtag tgcagcacga tgctgcggtt
     2401 gcccttggtc agcgggtgga aaaggtcctt cacgttctcg tcgtagaaga agccctggtt
     2461 cgtgaagtcc ccgatgtcgg gcactacctc gccgtcgacc ttggcacccg cggtgtcgag
     2521 cgtgaacgcc tcggtgatgt cgatggtgcc ggaatcgtcc cgcagcccga tgctgccgcg
     2581 atagacgttg agcacgctct tgaagaggaa gtcgatcctg gtactggtct tcgcggtccg
     2641 agtgatcccg gagaccgcct tcgccgtgcc gccgaggtgg atggcgaagg taccgacctt
     2701 gtagtaggtc tttgagacgt acttcagctt caccagctgg gcgccctcgg tggtcatcgt
     2761 gacgatgaac atgtagtact caccgtcgat cgtggcgagg gtcatgtcat tggcgtgccc
     2821 gagccaggag ttgtaggcca caccgtccgt tccgttggtc atgatctctg tggcaccgct
     2881 cgtccggttg gtccggtaga tgatcgctcg ggcatcgtcc gaacggatct tcacggagta
     2941 gagataggtc ccgccggcgg caaagccctg cgccgccgtg cacccatgtg cgttcggaat
     3001 cctggcgatc gtctcgtaat cgttgtagta cgcggcctgt gcgctaccgg ccggcacagt
     3061 cgccagcccc acaccagcag cgaggatgag cgcggaccgt cgtgtgatct ccatcggagt
     3121 accccctcgg cagtgaagaa ctgacctagc gaaacctcac gctatggcag ccggttatcg
     3181 ccgtcaacgg atctctcacc cggccctcac cacatcccac agcggcgttg ccggaacgaa
     3241 ctgcccgtgc gcgcccgtcg ccacgaagtc acgatcccgg acgactgcct ccccgcgaac
     3301 cagcaccgtg accggcaggc cacggatctc ccggccctcg tacggggtgt agtcggtggc
     3361 catgtgcagc gtgcttgtgc ccaccgtggc ggtcgcttct gggtcccaga tcgccaggtc
     3421 cgcatctgaa ccgggtgcga tcagtccctt gcgtgggtag aggccgttca gccgcgccgg
     3481 ggtggtggcg gtgaggtcca cgaactgggt caccggcatc agaccggacg agacgaactc
     3541 gctgaaagcc acgggcagtc gagtttcgac gccgggtagc ccgttcggca tggatcgcac
     3601 gtcatgcttg gtgaggagct tctgctcggt gtcgtagcag cagtggtcgc taccgatcgt
     3661 ggagaccccg ccggtcaaga gcttgctgcg cagcccctgc acggtgcgcg ccgagcgcag
     3721 cggtgggcag cacacgaacc gctcggggtg ctcggcggag tactcgctct catccagggt
     3781 gagatggtgc accacggcct ccccgtacgc ctggcggccc tcgctgcgag cgtgctccac
     3841 gagtgcgacg gcttccgggg ttgactggtg cacgaagtac accggtgcgc ccgcatgctc
     3901 ggccagcgcg agcaccgccg ccacggctgc ggactcggca agctccgggc gggtctcgtg
     3961 gtggtgcccg gcgctgatgt ctccgctgcg cgcgacctgg tcctgggtgt cctccacgat
     4021 ggtgttggcc tcgcagtgca cgtagaccat gccgccgagc gggctcaggt gcttcatcgt
     4081 gcgcaggatg gtctcttcgt tggccatcgt ctcgtcgcgg taggtggtga acagcttcac
     4141 cgtcaccacc ccttcaccca ccagctggtc cagctgcgcc ccggtgctct cgtcccagtc
     4201 caccacgcag gcatgcagcg cgctgtcgca gaagccttgc gtcgcctgtg cccgctgacg
     4261 gtgcacggca tcgaccacgc gttcgccgcg ggtcgggata ccgaagtcca cgatcgtggt
     4321 ggtaccgccg tggaccgcag ccctggtcgc ggccggatag tcatcgagcg tggtgaactc
     4381 accggaggtg aagcccacgt ggcagtgcgg gtccaccccg ccggggagca cgagcatccc
     4441 ggtggcgtcc acttcgtcat tgcccgacgg cgcatggccg ggttcggtca gcgccgtcac
     4501 ccggccctgg ctcacgcaga tatcggcgcg cacgatcgag tcggcgttga ccacctcacc
     4561 gccgcggacc accaggtctg gtcggctcac gcgttctccc gctcggccag gtaggcacgc
     4621 cagccgccgt gctcggtgat ctccaccgtt ccctcggctt cgatcgcctc ggtgcgcatc
     4681 accatcgaca acgagccggt accgtcctcg agctcaatga tgctcagctc cagctcgggc
     4741 ggctccagcg gcagcaactc gctgcgcagg gccgcgtagg agacctcgta cagctctccg
     4801 gcgatcgagg acccaccccg ctccgcccag gacaaccccg gaaactccgc ccgcaccgag
     4861 tagaagcggt acgcggccgc ggtggttgcc gcacccagga agcgcgcgtt gcgcaacccg
     4921 gagctgatcg atccgccgga catcgcctgc ccgttcacga acatcttcac cagttccatc
     4981 acaactcctt cgtcagtgcc tcagcgctgg tgcgctacgg cttcgagttc caatcgatcc
     5041 acgcccaggt cggccaccgg ttctgcgggg cggtttcctt ccaccaggtc acgcagcacg
     5101 tgtccccaca gcggagcgag ggtgaacgcg tacgtgccgc cggccacgaa gaaccccggg
     5161 ctggagggca cctcgccgat cacgggcatc tcgtccgggg tggcggccag cggccccgcc
     5221 caggtccgca gcaggcgtag ctcccgtagc accggcaaga tggccgcggc ctgatgcagg
     5281 ttcccgctga tgctctcggt ggcaacgcga ctgcgacctt cactgcggaa ctcggtggct
     5341 ggccaaccac cgccgatcag gatgttcccc gccgtcacct gcttgaccga cattcccgcg
     5401 ccgatgtgct gcaccaggca gctcaacgtc cgtggcggca tccgggtggt gatgtgcatc
     5461 tggatcgcca ccgggctcat gtccagcgcg atcccggcca gggccgccac atcggcgatc
     5521 cacggacccg ccgtgtcgat caccgcggcg gccgaccacg cccggtgact cgaccgcacc
     5581 acgtacgctc cgccgtcgcg ctcgatagcg gtgaccgggc tgaaggcttc cacctgagca
     5641 ccgtgccggc gggccgcggc caggtaggcg ggagtcacca gcagtgggtt ggcgtacccg
     5701 tcctcggcgc accactccgc ggcgatcacc gattcggaca gcgccggcat ccgcgaacgg
     5761 gcctcgtcac cggagacgat ctcgcaggac agcccgagtt cgagctccac ggccagcttg
     5821 gcgtgcagct cggcgacctg gtccggcgtc tcggccacca tgaacccacc gttacgggtg
     5881 agctcgatat cggcatccag ctcgtccggc aacgctgacc acatcgccga tgcggtgcgc
     5941 tgcaggggca ggaagcggag attgtccgcc gccactgcct ggccaggtcg tttggtgtgg
     6001 atgccctgga tgtgcaggtt gccggccgtg gtccctgaac cctcgcggtt cggtgctcct
     6061 cgttcgagca cggtgacctg gtgaccggct cgagccagtt ggtaggccgc cgaggccccg
     6121 aggatcccac cgccgatcac caccacgtcg gtcctgatca cagctgcctc tcctccatgg
     6181 ccatcgcggc gcgcaccggg atcggcttca ccggcatccg ggccggctgg cagccgacag
     6241 gttcgccggt gcacgccgag accaggcagg agacggtgct ggcgcactcg cgcccttggc
     6301 acggacccat accggcgcga gtggcgccct tgaccccgtt ccggtcattc cagccgagcc
     6361 gggcagctgt gcgaatctcc ccggcggtca cgctctcgca gcggcagacc atcgtgtggt
     6421 cgggcatggc cagcatcggc tcccggtcgt gcgcatacag gtcgctggtc agccggctga
     6481 agtcgtccag tcggcgggac cgtcgttcat acctgcgcac cgcccgctcc ggcggtgcgg
     6541 acaaccccag ctcctcccga atcgtcgccg cggcgagcca gccacgcacc tgggccccct
     6601 tgctgccggc gatcccacga gcctcgccga cggcgtagac ccccggggca ctggtcgcgc
     6661 cccgggcgtc cgtgtctggg atgggcaccc cgagctcggg gtcgaggctg cactccacct
     6721 ccagcagctg caacagctcg gtggcggggc ggaaccggac cgcggtggcc agggtgtcga
     6781 cgtcgaacga gcggttgccg gtcgtagtcg cgatgctgac cgtgcgtagc cgcccgtcgg
     6841 gccccgcggt ggattcactc acgtgtgcgc cctggaggat cggcacccgg tgccgggcca
     6901 gcacggtcag gtaccgggcc agctcgccca gcatgcccgg atgcgcggcg gcgccgaggg
     6961 cgcgcgccga cggccgcagc ggcctgcccg cctcgaccac cgcggctacc tcgctgccgg
     7021 aggcgagcac ggcgcaggcc accggcaaca ggaacggacc gctcccggcg atcagcaccc
     7081 gctgacccac ccgcaccaca tcggtggtgg ccaggtgcat cgcatgcccg ggggtgatca
     7141 ccccgggcag ctgccagccc ggaaacggga gtacgtgctc ggtggcgccg gtccccacca
     7201 cgatcgcccg ggcggtgaac cgcaccgcat cagggctggt ggtggaggtg gtcagcagcg
     7261 cccggtccgg cgtggttccc cacaccagcc ggttggtgtg cacctgcacc ccagcctggc
     7321 gaacctgcgc gatcagcgcg gtcccggcgg ggcggaaatc accgtgccgg gccagcacct
     7381 ggccgcggcg gcgcttgtag tactggccgc ccagctcggc gctctcctcg atcaacgcca
     7441 cccgagcccc cgccgtcgcc agttctctgg cggtgaccag accggagggg ccgccaccga
     7501 cgacgaccac gtcatagtcg aggtgactgg gagcggccgc gggctgtggg tcagtcgtgg
     7561 acacgtccca ccccctcagt gcgaaccacc aggccgcgtt cgacctcgac catgcacgcg
     7621 cgggtctccg ccgaaccgtc cacgtgcagc tcgcactcgt agcacacgcc catgccgcag
     7681 aacggagccc ggggagaacc gtccaccggg ttgctgcgcc acgtgcggat gccggctgct
     7741 tccatcgccc cggccaccga ctggcccgcc agggcgcgga gcggatcgcc gtccacggtg
     7801 atggtgagag gggcggcgtc gttgctgcgg ctcataccag ctggccgagg aacttgcggg
     7861 cgcgctcggt cttcggattg tcgaagaact cggccgggct ggcctgctcg acgatctcac
     7921 cgtcgtccat gaagatgacc cggtcggctg cggcccgggc gaaggccatc tcgtggctga
     7981 ccacgatcat cgtcattccg tccttgcgca ggttgatcag cgtctccagg acctccttga
     8041 ccatctccgg gtccagggcg gacgtcggct cgtcgaagag catgatgtct gggcgcatcg
     8101 ccagggcgcg agcgatcgcc acccgctgtt gctgcccgcc agagagatgg ctggggtagt
     8161 tcgcgccctt gtccggcagc cccaccatcg ccagcagctc cttggcggcg gcggccgact
     8221 tctgcttcga cttaccggcc acgtggatgg gcccggaggc cacgttctcc agcgcggtca
     8281 tgttcgggaa cagattgaac tgctgaaaca ccatcccggt acggcggcgc tgctccgcga
     8341 tccggctctc ccgcaacggg cgcaggccct tgccagtgcg gcgctgtccc atcagctcgt
     8401 cgctgatggt gatctcgccg gaatcgatgg tctccagcac gttgagggtg cgcagcagcg
     8461 tggacttccc gctcccggag ggacccagca gaagcacgac ctcgcccttg tggatctcca
     8521 ggtcgatgtc cttcaacacg tgcaggctgc cgaaggactt gttcaccttg tgcacccgcg
     8581 ccacgatctc ggtggtcggc ttgctggtgt gcggcggtgt ggccagagtg ctcatcggct
     8641 gactccttcc aactcggatt ccagctgcag ctccctggcc tcgctctggt tgggtgctgc
     8701 ccggtggctc ttgttcagga cggactcgat gcggctctgg atcagggtcc agatcgaggt
     8761 catcaagagg aagtacaggg cggcggccac gaggccctcc aggacccgga agtcgacttg
     8821 tacggcgtac tgcgtgcgtc ggagcagttc ctccacggag atcaccgaga ccagggtggt
     8881 ggtcttgagc atcccgttca gactgttgcc cagcggcggg accatgatcc ggaatgcctg
     8941 ggggagtacc accacgcgca tcaccttgat cgggctcatc cccagagccc gcgcggcttc
     9001 gtactggccc ttggccacgg acatgatgcc gccgcggact atctcggaga gataggccgc
     9061 ttcgttcagc gagaggccga tgatcgcgca ccagaccggg gagagcttca ggcccagctg
     9121 cggcagtccg gtgtagatga tgatcagctg gaccaggacc ggcgtgccac ggaagagcca
     9181 gatgtagaag tttccgaacc agcgcagcgg cagcacccgg gaaccccgcg caatcgccag
     9241 gaccagtccc aggatcaggc cgaggaccat ggtcacgacc gtgagccaga tggtggtgac
     9301 cgcaccctgg agcagggtct cggcggtcag gtaggtcagg aaggcgtccc aggaccacat
     9361 gtcaggtgtc ctcaccttcg agttcgaccg gaccggtggt cacttcgtac gggccggggt
     9421 acggagtgac tccgtagctg tcgaagagct cctggacgaa tccgtcgtcc accatctcgc
     9481 cgtaggtttc cgcgacgatg tcggcgagtt cgttgtcctt ggcgaacccg aacgccaacg
     9541 ggccggggtg caggcccgag atggcggtgg tgaaccggcc gtcctcctcg tagaagctgg
     9601 tgacggcctc gacgatcgcc accccgtcga tctgaccggc cgagagtgcc tggaaggcgt
     9661 cggcgttggt gagggaggtg ttgatgtcga gtgggtcgag gcctgcgtcg acgatctcgt
     9721 cgttcacggc gttgaccgag tcgaactcat agcccggggc ctcgactccg atggtgagac
     9781 cggccaggtc ctcgacggtc tcgatgccct cggcttcgcc gtcctgcacc gagatggcca
     9841 cagcctggac ctcgtacggc acgaggtcca gagtctcggc acgctcctcg gtgtagaaca
     9901 tgccggtgtt gatcaggtcc catcggtcgc cctgcacgcc cgggatctgt gcgtcgaagg
     9961 ggacgttcat cacttcggtc tcgaggcaca gtcgcgtggc gatctcggtg acgagctcca
    10021 cgcgcatgcc gaccacctcg tcgccgtcca cgtactgcat cgggggcagg gtggcgttgg
    10081 tggagaaggt gagggtgccg ggggtgatga gcagatcgtc ggagactgct ggctcgcagc
    10141 cgctgaggtc aggctcatct tcgccgccgc cggagcagga ggcgaggacg agggcaccga
    10201 tggcggcgcc gacggggaga agtcgcgtgg tacgcatggt cactccttgt gactgggctg
    10261 gtgggggctg agtcctgctt ccgccaacgc atgggcgagg tcggtgctgt tctcctcggc
    10321 catggccagc agtggcgggc ggacctgtcc acccggttga ccgaggaggt tcatcgcagc
    10381 tttgagctgc gaggtggggg aggcgaactt cgagctgtag tcgttgttga ccagcacgga
    10441 gaccaggcgc gcgtaccggg tgccgtgttc tcgggcggcc tcgagattgc cggcgaagac
    10501 ctcgttgtag aacgggacgg cgaaaggagc accgagcccg ccgccgtcga tgttcccgtc
    10561 tccgcccacg ccgagcatga aggccatccc gcgtgggtgg atgaaccggc cgaaggcgcg
    10621 cacccgatcg gccacggcct ccacggtttc catgcacttc agctcgtcgc cggtgctgtc
    10681 cttgatggcc accacgtgcg gcaggtccgc caggagcgag gccgtctcca ccgagatgtc
    10741 cacggcggtg ccacggggcc agttgtacgc catccagggg atctcgacgg cgttcgtgac
    10801 cgtctcgtag aaggcgtaga tctcgtcctg ggacgggtgg gcgtacgggg gaggggtggc
    10861 cagcgcgcca tccgcgccga tcgccttgac ctcgcgggcg agttcgatgg tctcgcccgg
    10921 ggtgtacgtg gtgcatccga tgaccaccgg gattcggccg gcgaccgtgg ccacggcgat
    10981 ctcggccacc cgccggcgct ctgcccgggt ctgggagaac cactcgccgg tggtcccgtt
    11041 gatcagcacg ccatgaacgc cctggtcgac gtacagcgcc aacagccgca ccaggccgtc
    11101 ctcatcgagt tgcccgccgg ctgtgtaggg cgtcggggcg gcgggccagt agccgcgcca
    11161 cggcacatcg cttcgctgca tggggtcctc actgactatt gggatcgatc ccaagaatga
    11221 aagcaggatc atgacacggc gtcaagcact ccacccacgg taggcgtaga tacgctagcg
    11281 ttatcagcgg aaagtcgaga tgagtctgga gttggatcaa tggcatcgat cccaaagcgg
    11341 agggcaacgc tgctcgacgt ggctgccgct gctggcgttt cgcgcagtac ggcgagccgg
    11401 gtgctcagtg gtgagggggc ggtatccgcc ggcaccgagg agcgcgtgcg ggccgcggcg
    11461 gcggaggtcg ggtacctgct gaacagcgct gcgcgcacgt tgcggaccag ccgcaccatg
    11521 ctcaccgggc tggtcctgaa caacctggtg aacgccacgt ttcatgtggt ggccgagatc
    11581 gtgcagcagc ggctcgcgca ggacgggtat cggatgatcc tctgcgtcac gggcgggcag
    11641 gccgaggagg aggccgagta cctcaccacg ctcgccgagc agggggtgga cgggatcatc
    11701 gtggtgggca gcggcgcgaa catcgagcag ctgaacgcaa tccaccgggc cggtaccggg
    11761 atcgtgaacc tgatccgggc cggtaagggc gcgccggggg accgggtact cgcctcagac
    11821 cgggacggtg cggtactggc cacggaagag ctgctcgagc tgggccatcg ccggatcggc
    11881 tacatcgggg gaccggcgca gacgaactcc ggacgtgaac gcttccaggg ctaccagaac
    11941 acgatgcacg ccgccggcct gttcgccgag gacctggtgc tgcgtgggcc gttcagcccc
    12001 gacttcggtg cggaagcgat ccagcagatg ctgcgggtgc cggagccacc caccgcggtg
    12061 tacgtggcca accacgaggc atccttcggt gcgctgccga cgctgcgcga cctgcaggtg
    12121 cgcctacctg ccgacctttc cctgatcgcc cacgacgaac cctcctggtt ccagtactgg
    12181 gacccggcgg tgagcatcgt ggacagcgga ccggtggagc tggccgaact cgccgcgacc
    12241 cgactgatcg ccgccatgcg gccaggcggg ttggcagagc ggccgcggga gttccgggtg
    12301 ggcgcccggc tggtgacgcg tgggtcgagt gcggcgctag ggtcttgagt gggcccggtc
    12361 agggctgttc agattgaagc ggcgaaggtg aggcccttca tcatgggctg gcgtcaactg
    12421 ccatcaggac tgccgcacga tcagctcggg tgtcagcagc acgctctgga cttcggtgtc
    12481 gccgtcaagc ttgcggatca gcgcgtcagc gctcaagcga ccgatctgct cggcgctgat
    12541 cgccactgtg gtcagtgggg gctcccagag ctgcgcctcg agaaggtcgt ccgatccgac
    12601 gatgcaggtg cgttccagca gaccaggaga gtggtcccgc aacgcccgag tggcgccgaa
    12661 cgcgatggtg tcgttgtgga agatcagcgc ttccggcacc tgccgctctt ggagcagctg
    12721 cgccataccg gtccgggcag cctgcgctgt gaggctcgtg ggaacgtcga acgacagctc
    12781 gatgccttcc gctgccagga cctcccggac gccggacacg cgatcggagc gcagc
//
