LOCUS       NZ_VOGX01000092        22586 bp    DNA     linear   CON 15-OCT-2024
DEFINITION  Streptomyces albidoflavus strain 77 scaffold41_cov50_12811_301297,
            whole genome shotgun sequence.
ACCESSION   NZ_VOGX01000092
VERSION     NZ_VOGX01000092.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 288487)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   2  (bases 1 to 288487)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUL-2019
            Assembly Method                   :: SPAdes v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 36.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007896905.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 04:20:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,551
            CDSs (total)                      :: 6,456
            Genes (coding)                    :: 6,343
            CDSs (with protein)               :: 6,343
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 34 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 8 of 113
            Pseudo Genes (multiple problems)  :: 8 of 113
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:41:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 57648
            Orig. end                         :: 80234
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOGX01000092.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..22586
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="lanthipeptide-class-iii"
                     /region_number="1"
                     /rules="(micKC and not PKS_KS)"
                     /tool="antismash"
     cand_cluster    1..22586
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(micKC and not PKS_KS)"
                     /kind="single"
                     /product="lanthipeptide-class-iii"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..22586
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[10000:12586](-)"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(10001..12586)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(micKC and not PKS_KS)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iii"
                     /protocluster_number="1"
     misc_feature    complement(330..345)
                     /note="TFBS match to DasR, N-acetylglucosamine dependent
                     repressor, confidence: weak, score: 19.62"
                     /tool="antismash"
     misc_feature    complement(821..834)
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.35"
                     /tool="antismash"
     gene            1344..1868
                     /locus_tag="FRZ02_RS31560"
                     /old_locus_tag="FRZ02_31560"
     CDS             1344..1868
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415563.1"
                     /locus_tag="FRZ02_RS31560"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31560"
                     /product="hypothetical protein"
                     /protein_id="WP_008415563.1"
                     /transl_table=11
                     /translation="MTSLPRGGAARQFSPATRRGFAVLGAVSAGLLVLSACDKPTAVAT
                     VTIGSDSVNSEATCWNGGSKIDEKKLQQCLQDKGEGDSGDGAEVKTVKVDTEADVHIGV
                     DPKIADKGWTILMNGQPLTDASNKTFRTIPGSVFFNQQYGASGDSTVLSILENDGSSAT
                     GLWSFKLEKES"
     gene            1889..2614
                     /locus_tag="FRZ02_RS31565"
                     /old_locus_tag="FRZ02_31565"
     CDS             1889..2614
                     /EC_number="3.2.2.26"
                     /GO_function="GO:0016799 - hydrolase activity, hydrolyzing
                     N-glycosyl compounds [Evidence IEA]"
                     /GO_process="GO:0009234 - menaquinone biosynthetic process
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010643335.1"
                     /locus_tag="FRZ02_RS31565"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31565"
                     /product="futalosine hydrolase"
                     /protein_id="WP_129828352.1"
                     /transl_table=11
                     /translation="MRLLVATAVPPERDAVARAFGAPDTPEETALPGAVLLRTPGADVL
                     AAGVGPAAAASATSAALTAARLAGNPYDLVVSAGIGGGFAERAPVGAVVVADRIVAADL
                     GAETPDGFVPVTGLGFGTDVHVPPAALVEAAREAGLVPGAVLTVSTVTGSADRTAELLA
                     RHSSAVAEAMEGFGVAEAAAAHGVPVLEIRAISNAIGPRDRDAWRIPAALTALTSAFVR
                     LAPAEAGSPFALARARLVP"
     gene            2682..3575
                     /locus_tag="FRZ02_RS31570"
                     /old_locus_tag="FRZ02_31570"
     CDS             2682..3575
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008415567.1"
                     /locus_tag="FRZ02_RS31570"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31570"
                     /product="1,4-dihydroxy-6-naphthoate synthase"
                     /protein_id="WP_146583385.1"
                     /transl_table=11
                     /translation="MSESGAGGVQGTADEAGRLSIAYSPCPNDTFVFDAVAHGRVPGAP
                     ALDVTFADIDLTNGMAERGAYDVLKVSYAALPWLLDEYALLPCGGALGRGCGPLVLTRE
                     ASLPGALAGRTVAVPSERSTAYLLFRLWAADQVPGGVGEIVVMPFHEIMPAVRDGKVDA
                     GLVIHEARFTYQNYGLHKLADMGEHWEATTGLPIPLGAIIARRSLGAERLTALAQALRT
                     SVRMAWDDPAASRPYVLAHAQEMDADVADQHIGLYVNEFTADLGEDGYAAVRGLLTRAA
                     AEGLVPPLAPDALRFP"
     gene            complement(3667..4050)
                     /locus_tag="FRZ02_RS33820"
                     /old_locus_tag="FRZ02_31575"
     CDS             complement(3667..4050)
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0001072 - transcription antitermination
                     factor activity, RNA binding [Evidence IEA]"
                     /GO_function="GO:0003676 - nucleic acid binding [Evidence
                     IEA]"
                     /GO_function="GO:0003723 - RNA binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1255: cold-shock
                     DNA-binding domain protein"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016642928.1"
                     /locus_tag="FRZ02_RS33820"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31575"
                     /product="cold-shock protein"
                     /protein_id="WP_003950021.1"
                     /transl_table=11
                     /translation="MPTGKVKWFNSEKGFGFLSRDDGGDVFVHSSVLPAGVEALKPGQR
                     VEFGVVAGQRGDQALSVVLLDPAPSVAAAQRRKPDELASIVQDLTTVLENVSRSLERGR
                     YPDRASGAKVAGMLRAVADQLDV"
     misc_feature    complement(4098..4107)
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 13.3"
                     /tool="antismash"
     gene            4192..4443
                     /locus_tag="FRZ02_RS31580"
                     /old_locus_tag="FRZ02_31580"
     CDS             4192..4443
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950020.1"
                     /locus_tag="FRZ02_RS31580"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31580"
                     /product="hypothetical protein"
                     /protein_id="WP_003950020.1"
                     /transl_table=11
                     /translation="MSDTTQQTPAPGDRLVKTGGIVFIIGALATLVTVAPLFLGSDPFP
                     TAAYLVSMLMGVGFLIAGAGLVRQIAAQRRETRAAVEG"
     gene            4718..5461
                     /locus_tag="FRZ02_RS31585"
                     /old_locus_tag="FRZ02_31585"
     CDS             4718..5461
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="regulatory (smcogs) SMCOG1016: LuxR family
                     DNA-binding response regulator"
                     /gene_kind="regulatory"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507350.1"
                     /locus_tag="FRZ02_RS31585"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31585"
                     /product="response regulator transcription factor"
                     /protein_id="WP_176725969.1"
                     /transl_table=11
                     /translation="MSRAQTTARVQVIHSSGVLRSALVALLERERFQVTSASGFSRASS
                     GTTGAPGTPGAPATVTVVDGSCPVGAAHLERRSLQGSAKEPTHATPALAAARPGLGLAG
                     AGAERAGIGLAGASRGRAALVVLAGAEHPGVLRLAYAAGAIGLVDRDGPANHLATAIRL
                     AAGGGRYVDDGLAMSLLRAMDMPLSPREVRVLSRAAQGDSVAEIARGLCLSHGTVRNYI
                     ASATRKVGARNRVDAIRISRAAGWV"
     gene            complement(5798..7729)
                     /locus_tag="FRZ02_RS31590"
                     /old_locus_tag="FRZ02_31590"
     CDS             complement(5798..7729)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469939.1"
                     /locus_tag="FRZ02_RS31590"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31590"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_067414592.1"
                     /transl_table=11
                     /translation="MTRPRHTDGAPSPLLRPALTFARRRKGPLGALGAWSLLESARTFL
                     TGYAVARALDDGFLAGDVRTGLLWLLALAAAALAGGFADAGVFRALGGVIEPLRDSLVR
                     RVVRATLTRAVASPTPADTARVSRLTAQTEIARDAAGGVLLTVRSFLFTSAGAFTGLAA
                     LSPRLLPLVLIPLAAGLALFAATLRPMAARQRDLLDADEHLAAFAGRTDHAARDIAATG
                     AAPLVTAEAAPLITAEATAASALARWSAVRVTALGLAAHLPVATLLLAAPPLLSTGLTP
                     GELLAALTYVTTALLPAVNALLTALGAAGSRLLVVLHRLLGEEADAADVREEQAHALRV
                     DDGPRAPGACSQGKADDEVPAIPAPSLPPEPVHGPEPFRAEPSPPGPRPTRGPRPTRPA
                     LPAATLRGVTFAYGPDAAPVLDHLDLTVEPGEHLLVVGPSGAGKSTLLALLAGTAPPRH
                     GQIHLAGHTARHARTLGTAARVLVPQEPYIFEAPLHDNLTYLAPNAPAPRITEAIHTFT
                     LTPLAADPARPLRPDHLTPSERRRIALARAWLTPTPLLLLDEPTAHLDAGARAATELAF
                     ASHPATVITVSHHFPAPEPGQRVLLLDGATPYLGTHASLLRESALYGELAAGLGEPSAA
                     GSRSTAST"
     gene            complement(7726..9621)
                     /locus_tag="FRZ02_RS31595"
                     /old_locus_tag="FRZ02_31595"
     CDS             complement(7726..9621)
                     /EC_number="7.-.-.-"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896359.1"
                     /locus_tag="FRZ02_RS31595"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31595"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146583386.1"
                     /transl_table=11
                     /translation="MTAAPADAARARATPAPPPAEGRLLREAVRRGRGPAALVLAATAL
                     GAAAAVTLPLALGRAVDLLIARADAGSWVLLCTALIATEVATDALVARTGGRTGAATTA
                     WLRRRALAGFLAAPPAATTGTGLPTRLTANALDAGTAPVAAATAAAAGLAPLGGLAGLF
                     LVDPWAGAAFVCGVPLLLLILRALLRDGRAALTTYQEEQGRMARLLTGALSGAATIAAA
                     GTVRAEERRVLAPLAGMRAAGERTWRVQGRAAGLSGALMPLLVAAVLAVGGVRLVAGHL
                     TPGDLLALSRYAVLAAGAGALAGALNSWVRAKAGTARVETVTALPPTPHGTRDLPPHGD
                     GTLALHGVHVTRDGVPLLDSVTLTLPGGTTTALVGPSGSGKSLLAAVAGRLTDPVQGTV
                     LLDGTDLRTLSADTLRHAVAYAFERPALFGATIADAVACGPLPEPELRRALRRAAADTF
                     TDRLPHGPRTPLPEAPLSGGELQRLGLARAFTRPTRLLILDDATSSLDTVTAHLVARAL
                     TDTPGTRLTITHRLTTAAQSDQVVWLDGGRIRGRGPHSVLWRDPAYRAVFGAGAGGDAG
                     AGADTVTDTGARTRSDVRTDVSSDVRTELPADMRTDLHTGIRTDPRVDTGTGAVE"
     gene            complement(9780..9911)
                     /locus_tag="FRZ02_RS31600"
                     /old_locus_tag="FRZ02_31600"
     CDS             complement(9780..9911)
                     /codon_start=1
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015611153.1"
                     /locus_tag="FRZ02_RS31600"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31600"
                     /product="SapB/AmfS family lanthipeptide"
                     /protein_id="WP_008415578.1"
                     /transl_table=11
                     /translation="MALLDLQAMDTPQEEAVGDLATGSQISLLICEYSSLSVTLCTP"
     CDS_motif       complement(9846..9911)
                     /prepeptide="leader"
                     /note="peptide class: lanthipeptide"
                     /note="predicted sequence: MALLDLQAMDTPQEEAVGDLAT"
                     /locus_tag="FRZ02_RS31600_lanthipeptide"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
     CDS_motif       complement(9780..9845)
                     /prepeptide="core"
                     /locus_tag="FRZ02_RS31600_lanthipeptide"
                     /peptide="lanthipeptide"
                     /predicted_class="Class III"
                     /score="30.10"
                     /molecular_weight="2088.4"
                     /monoisotopic_mass="2087.1"
                     /core_sequence="GSQISLLICEYSSLSVTLCTP"
                     /aSTool="lanthipeptides"
                     /tool="antismash"
                     /leader_sequence="MALLDLQAMDTPQEEAVGDLAT"
                     /leader_location="[9845:9911](-)"
                     /alternative_weights="2106.4"
                     /alternative_weights="2124.5"
                     /alternative_weights="2142.5"
                     /alternative_weights="2160.5"
                     /alternative_weights="2178.5"
     gene            complement(10001..12586)
                     /gene="lanKC"
                     /locus_tag="FRZ02_RS31605"
                     /old_locus_tag="FRZ02_31605"
     CDS             complement(10001..12586)
                     /GO_function="GO:0004672 - protein kinase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /GO_process="GO:0006468 - protein phosphorylation [Evidence
                     IEA]"
                     /codon_start=1
                     /gene="lanKC"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iii: micKC"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Pkinase"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LANC_like"
                     /gene_functions="regulatory (smcogs) SMCOG1030:
                     serine/threonine protein kinase"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507351.1"
                     /locus_tag="FRZ02_RS31605"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31605"
                     /product="class III lanthionine synthetase LanKC"
                     /protein_id="WP_146583387.1"
                     /sec_met_domain="micKC (E-value: 2.1e-223, bitscore: 737.9,
                     seeds: 18, tool: rule-based-clusters)"
                     /sec_met_domain="Pkinase (E-value: 9.3e-14, bitscore: 45.4,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.3e-06, bitscore:
                     20.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPEYALYSGTDRWFYDTPRRAGRTADGSGNANGSDGHRYALARR
                     PVPEGWESAERGDWFSLAPAGRQLPAQGWKIHVSATPDNAEEVLETVAGICQERATAFK
                     FLAGPALLLHRNTKYADRAGSGKFVTVYPATTAACGELAAELADALKGSAGPVVLSDLR
                     WGEGPVHVRYGAFAPRFTRAADGSLVPAVADPAGRLVPDTRGPAFRLPDWVELPDFLRP
                     HAEARAAQGTTDLPYTVERALHFSNGGGVYAGSHRETGEAVVLKEGRPHAGLAADGADA
                     VTRLEREYAALRALEGLACVPRVHGLHTVGEHRFLAMEFIPGTPLNTVFARRFPLSAAE
                     PAAEALAEHTAWALRTHQLVTEAVEALHTRGIAFGDLHMNNIMVAPDQLSVTLLDFEAA
                     TPAAERRPQIVANPAFVAPPHLRGTEVDRYALACLRLALFVPLTTLLPLDRDKAAHLAG
                     LAADRYGIDRALFDEAVTELAGPARPEAGPSRGRPPVSATDWPAARDSMVAALLASATP
                     GRDDRYFPGDIAQFATPAGGQSYGYGAAGVLHALHTVGVRCEEAEEWLIRTTRHPASGT
                     PTGFYDGLTGIAWTLDRLGHREEALRLAHLVAAEPLDALGPGLHSGAPGVALALRDLAD
                     ATDDPALGQAADRAEAAALRPAAPGGKAGLLHGPAGTALLCLRRHARTGEPALLDTAAT
                     ALREELGRCVPGPDGSLVVSEARRTMPYLGSGSAGIAMVLDDYLDRRPDPAFEEARTAL
                     LRATGSAFYIQPGLFRGVAGLLLHLARTTTPGDRAARTALLTRQTALLDWHALTYQGHL
                     AHPGEQLTRLSMDLSTGTAGVLLALAATHGEPAAHLPFLPPLRRPTDRP"
     gene            complement(12799..13776)
                     /locus_tag="FRZ02_RS31610"
                     /old_locus_tag="FRZ02_31610"
     CDS             complement(12799..13776)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1033: iron
                     compound ABC transporter, periplasmic"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018469936.1"
                     /locus_tag="FRZ02_RS31610"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31610"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_146583388.1"
                     /transl_table=11
                     /translation="MTRRTARPLLAATGALALALTLTACGSGEKTADDAGKDAGATRTV
                     KTAMGEVEVPEAPKRVVVLDTAELDSALTLGVKPVGAVRSDAAGGFASYLPEKELAGIE
                     NVGVIAQPNLEAIAALEPDLILTSKVRDEARYAQLSKIAATVMTENTGYPWKENFQVHA
                     EALGKQKEADRATAAYEKRTAEVTEAVGGPAEAEKTEVNVVRFVEGADIRIYGKKNYIG
                     TLLADVGLGRPAITDKATDGFSYDVSPEKIDLADADVVFTATYGDPEKAKETQTTRSAL
                     WRSLDAVKSGAVHKVEDELWIQGIGYTAAQQILDELEEALTPAS"
     gene            complement(13773..14627)
                     /locus_tag="FRZ02_RS31615"
                     /old_locus_tag="FRZ02_31615"
     CDS             complement(13773..14627)
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950013.1"
                     /locus_tag="FRZ02_RS31615"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31615"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146583389.1"
                     /transl_table=11
                     /translation="MTRPAARLTARDLTLAYEDRTVVPGLDLDIPDGRVTVIIGPNACG
                     KSTTLRALGRLLRPAGGAVLLDGAELARLPTRQIARQIGLLPQTPVAPEAITVADLVAH
                     GRQPHQRWWQQWSEEDERAVTEAMARTATTDLADRPVDALSGGQRQRVWIAMALAQETG
                     LLLLDEPTTYLDLAHQVEVLDLVRRLNREQGRTVVLVLHDLNQAARYADHLIAFREGRV
                     VAEGAPAEVVTAGLVREIFGLECVVVPDPVTGSPLVVPGAPWDARPAPEPAVPTREESR
                     ATP"
     gene            complement(14624..15721)
                     /locus_tag="FRZ02_RS31620"
                     /old_locus_tag="FRZ02_31620"
     CDS             complement(14624..15721)
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896363.1"
                     /locus_tag="FRZ02_RS31620"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31620"
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="WP_146583390.1"
                     /transl_table=11
                     /translation="MSGGSVALKAGPEPARVRPAGYVPVRVGPASLLVPVRAVATGAVL
                     AGVLAVVCVAYLSVGESFVAPGSVVDVLLGRPSPDTLVVGELRLPRMVAGLYVGAAFGI
                     AGALIQTVARNPLASPDLIGVSQGASAATVAALTFGVTSYTVLPWISVGGGLLAALLVY
                     LFAWRGGLQATRFVLVGVGFAVALRALTTLFLTKGDQTVAQQAQVWMSGSLNGRAWPEA
                     ALVGWTLLAALPALVWAARAQRTVTLDDATATSLGARLGRARLGLVLVGVVLASVATGA
                     AGPVDFVALLAPQIARRLARTAQIPLVCSALAGAVTVVAADLLARRLFAPTELPVGVLT
                     AAVGAPYLIWLLVTRHGPRATGGTS"
     gene            complement(15718..16782)
                     /locus_tag="FRZ02_RS31625"
                     /old_locus_tag="FRZ02_31625"
     CDS             complement(15718..16782)
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018896364.1"
                     /locus_tag="FRZ02_RS31625"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31625"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_127450441.1"
                     /transl_table=11
                     /translation="MPPAPPAAPSPAKAPPTAPRPRRDSAVRRAAWTVAALAALLVAVV
                     LSLAVGARTVAPGTVVEALFQGATGPDAEVVREMRLPRTLIGVMVGAALAVAGTALQGI
                     TRNPIADPGILGISQGASVGVVLAIAFAGVHTLAGYVWFAFVGAGLAAVAVYAVAAGGR
                     GGATPVKLALSGAAINALLVSVTTAVLTTSSSALDEFRFWNVGALQGRGADVAVQVWPF
                     LLVGLALVASSARGLDALALGEDVAKGLGQRVAAVRITAGAGAAVLTGVGVAAAGPVAF
                     VGLAVPHLVRHLVGGDHRWVLPLAALTGPVMLLASDTVGRVLFPPGEVPAGVMTALIGV
                     PFLVALVRSRAVTA"
     misc_feature    16865..16885
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.07"
                     /tool="antismash"
     misc_feature    complement(16866..16886)
                     /note="TFBS match to MntR, Manganese transport regulator,
                     confidence: weak, score: 21.11"
                     /tool="antismash"
     gene            16915..17598
                     /locus_tag="FRZ02_RS31630"
                     /old_locus_tag="FRZ02_31630"
     CDS             16915..17598
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1115: HAD-superfamily hydrolase, subfamily IA,
                     variant"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507353.1"
                     /locus_tag="FRZ02_RS31630"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31630"
                     /product="HAD family hydrolase"
                     /protein_id="WP_146583391.1"
                     /sec_met_domain="HAD_2 (E-value: 1.3e-11, bitscore: 39.0,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPEHLTSAAPAPSDPAVPAARPVPGGAGPVVGFDLDMTLIDSRPG
                     IGAAYRVLAAETGVPIDVDLVVSRLGPPLETELACWFPAEQVPAAAARYREVYPTTAIA
                     PSLALPGASAALEAVRAHGGRSLVVTAKNEEHARLHLDHLGLRADLVVGSLWAEAKGGA
                     LRAQGATVYVGDHVGDVRGARAAGAFSVAVATGGCTPDELRTAGADLVLPDLTAFPAWL
                     AEFAR"
     gene            18837..19892
                     /locus_tag="FRZ02_RS31640"
                     /old_locus_tag="FRZ02_31640"
     CDS             18837..19892
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015507354.1"
                     /locus_tag="FRZ02_RS31640"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31640"
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="WP_146583393.1"
                     /transl_table=11
                     /translation="MKQPARTAGGAVAEEARTVEGVEGDGPVKGEPGRTVEWWVALRRT
                     PGAFWRDDISDFAAALTYYAILAVLPALLVVVIAFGLVSPDTAERFVGQVTAWAPGGSG
                     ASLREVLTRVVRVDSTAWTLLVTGGASALWSASSYLAVSRRALHRMYGVRDRRSPWGKA
                     HRIVATALALLALLLVSSLLLMLTEPVAESIGRLLGLDAGVAWAWSVLRWPLLLCLVAC
                     LVVVVFRNGPVAARRRAHSIPGGVLAATLWLTASAGLALYASVLSTYSRLYGSLAGIVV
                     FLVWLWLSNVALLLGAQFTAELCRAAGGPGAPACHPEPAEEVAAQGASAGAEDAEDAEE
                     TREHGRAPTGA"
     gene            20013..21986
                     /locus_tag="FRZ02_RS31645"
                     /old_locus_tag="FRZ02_31645"
     CDS             20013..21986
                     /GO_component="GO:0005777 - peroxisome [Evidence IEA]"
                     /GO_function="GO:0003997 - acyl-CoA oxidase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006635 - fatty acid beta-oxidation
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003950008.1"
                     /locus_tag="FRZ02_RS31645"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_31645"
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="WP_315898876.1"
                     /transl_table=11
                     /translation="MTHGQLGPIHDSLATVTLQSVITEREIPLRHGSISASVSTADDLL
                     FATRGEEHLRWRELFSTEEFGHRDLPHRERVELSYRRLRTVAAAIPDPRALALSAPALT
                     ALHEWAGPADPGMATLASIHYNLFLGSLLDHDHAERDLEPWLRMDRIGTFLCTEAEHGN
                     DAVNMETTAEYDRASRQFVLNTPGPGAAKWMPNTSLTGGPKDAVVAARLLVDGRDLGIF
                     LFLTPLSNERGHLPGVSVERLPHTSGAPVDHCATRFHHVRLPHSAMLQGDHGRLSPDGE
                     FESTLGSPRIRFLRSIGRVSMGKLCMSGYSLGATRQAVAVAVRHGSTRLTSGMTKGRRV
                     PLMAHRSHHEPLLDALATTYAATLLHRSVVRQWEVAEEAEREEVDRLVAVTKGWITWAA
                     RETMTTCRERCGAKGLLLTQGIAGQLAANEGTITAEGDNQVIWVKAAGELLMGGFTPKP
                     PSETAPEQRSLRDGTHLQDLMADVERIWHERARTRLRTGGVRGNPMARWNGAVTPALEL
                     VAAHAHRLAGEALLEGSDRVTGDEAERIRDLHRLFALRQVAAHSGELLAGERLTAEQVR
                     RLPDEVERVVADLEPHALALTERFFVPEQVPGSDPAGLVETAGLVEAADLVEPAPEAVA
                     GAVPAGAESRAGGLRESEPDAA"
     misc_feature    complement(20028..20041)
                     /note="TFBS match to CatR, H2O2-responsive repressor,
                     confidence: medium, score: 19.02"
                     /tool="antismash"
     misc_feature    complement(20059..20072)
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 13.71"
                     /tool="antismash"
     misc_feature    20064..20066
                     /note="tta leucine codon, possible target for bldA
                     regulation"
                     /tool="antismash"
ORIGIN
        1 acggtggcgc tggcctcgac ggtcttcttc tcggtgccga cggacgaggc acgggggcgg
       61 gtggcgctct acctggccgt gacgatgctg ccgttcaccc tgctggcgcc ggtggtgggt
      121 ccgctgctgg accggctgcc gcacggccgg cgggcggcga tggccgggtc gatgctggcg
      181 cgggcggtac tggcgctggt gctgtcgggg gcagtggcga cgggcagcct ggagatgtac
      241 ccggccgcgc tcggcgtcct ggtggcctcg aaggcgtacg gggtggtgcg cagtgccgtg
      301 gtgccccggc tgttgccgca agggttctcg ctggtcaagg ccaattcgcg ggtgacgctc
      361 ggcggcctcc tggcgaccgg ggtggcggcg ccggtcgggg cggggctcca gatgatcggc
      421 ccggggtggc cgttgtacgg ggcgtgtctc ctcttcctcg gcggcgcgtt cctctcgttc
      481 cggctgccgc cgaaggtcga ctcggcgcgc ggcgagcggc gggcactgct ggcggcggac
      541 gagcagcacc tcgcggcggc ggtggacgcc cgctgggacc cggtgacgac agacgacaag
      601 acagacgaca agacagacag cacagacaac aaggaggaag agaaggacag ggacagggac
      661 agggacaggg acagggagag taggaagggg aaggagaagg agcggcggcg gaaggggccg
      721 gggctcagga cggtcgggcc ggcggtgacg catgcgctgg cggccaatgc ctgtgtgcgg
      781 tgccagagcg ggttcctcat cttcttcctg gcgttcctgc tgcgtgagca tccgctgacg
      841 gggcagagcg cggcggtgtc gctggcggtg gtcggtgtgg cggcgggggc ggggaacgcg
      901 ctggggacgg cggtcggggc gtggctgcgg gcccgggcgc cggaggtgat catcgtgacg
      961 gtggtggggg cgctggtggc ggtcgcggtg tcggcggcgg tgttcttcgg cgcggcggtg
     1021 gtggcggtgc tgggggcggt ggccgggttc acccaggcgc tggccaagct gtcgctggac
     1081 gcgctgatcc agcgtgatgt cccggagctg gtgcggacgt cggcgttcgc ccgttcggag
     1141 accttgttgc agatggcgtg ggtggtaggc ggcgcgatcg ggatcgcgct gccgctgcgc
     1201 gggccgctgg ggctgagcgt gggcgcgctg atcgtggcac tcggctggct gacaaccgta
     1261 cgggcgctcc tggcgtcggc cagacgcggc gcgtcgcacc cccgcgtggc gtgacgctcc
     1321 aacgggcccg atagccttcg cccatgacat ccctgccccg cggcggagcc gcacgtcagt
     1381 tcagcccggc cacgcgccgc gggttcgccg tcctcggcgc ggtgtccgcc ggcctgctcg
     1441 tcctgtccgc ctgcgacaag ccgacggcgg tcgccaccgt caccatcggc tccgactcgg
     1501 tgaactccga ggcgacgtgc tggaacggcg gctccaagat cgacgagaag aagctccagc
     1561 agtgcctcca ggacaagggt gagggcgact ccggcgacgg cgccgaggtg aagaccgtga
     1621 aggtcgacac cgaggccgac gtccacatcg gcgtcgaccc gaagatcgcc gacaagggct
     1681 ggacgatcct catgaacggc cagccgctga ccgacgcgtc caacaagacc ttccggacga
     1741 tcccgggcag cgtcttcttc aaccagcagt acggcgcctc cggcgactcc accgtcctct
     1801 ccatcctgga gaacgacggc agctccgcca ccggcctgtg gtcgttcaag ctggagaagg
     1861 agtcctgacc cgcctgccca cgcccgccgt gcggctgctc gtcgccaccg ctgtcccgcc
     1921 cgagcgggac gcggtggcgc gcgctttcgg ggcgccggac accccggagg agacggccct
     1981 gcccggcgcg gtgctgctgc gcaccccggg cgccgacgta ctggccgccg gggtcggccc
     2041 ggccgccgcg gcgagcgcca cctcggcggc gctgacggcg gcccggctcg cgggcaaccc
     2101 gtacgacctc gtcgtctcgg ccgggatcgg cggcggtttc gccgagcggg cgccggtggg
     2161 cgcggtggtg gtcgcggacc ggatcgtcgc ggccgacctg ggcgcggaga caccggacgg
     2221 cttcgttccg gtgaccgggc tcgggttcgg tacggacgtg cacgtgccgc ccgccgcgct
     2281 ggtcgaggcg gcccgcgagg cggggctcgt accgggcgcg gtcctcaccg tctccacggt
     2341 gacgggcagt gccgaccgca cggccgagct gctggcccgc cactcgtcgg cggtggccga
     2401 ggcgatggag ggcttcggtg tcgcggaggc ggccgccgcg cacggcgtgc cggtgctgga
     2461 gatccgcgcg atctccaacg ccatcggccc gcgcgaccgt gacgcctggc ggattcccgc
     2521 cgccctcacc gcgctgacct cggccttcgt ccgcctcgcc cccgccgagg cggggagccc
     2581 cttcgccctg gcccgcgccc ggctcgtacc gtgagcggtg gcaggacgcg cggcacaggc
     2641 ggcgcgagca gtgacagcag cggcgaaggc gaggcggcga catgagtgag agcggtgcgg
     2701 gcggcgtaca ggggacggcc gacgaggccg ggcggctgag catcgcctac tccccctgcc
     2761 ccaacgacac cttcgtcttc gacgcggtcg cccacggccg cgtcccgggc gcgcccgcgc
     2821 tcgacgtgac cttcgccgac atcgacctca ccaacggcat ggcggagcgc ggcgcgtacg
     2881 acgtcctcaa ggtctcgtac gcggcgctgc cctggctgct cgacgagtac gccctgctgc
     2941 cgtgcggcgg ggcgctcggc cgggggtgcg gcccgctggt gctgacccgc gaggcgtccc
     3001 tgccgggggc gctggccggg cggacggtgg cggtgcccag cgagcggtcg acggcgtacc
     3061 tgctgttccg gctctgggcg gcggaccagg tgccgggcgg ggtcggggag atcgtggtga
     3121 tgccgttcca cgagatcatg ccggcggtcc gggacggcaa ggtcgacgcg ggcctggtca
     3181 tccacgaggc gcgcttcacc taccagaact acggccttca caagctggcc gacatgggcg
     3241 agcactggga ggccacgacg ggcctgccga tcccgctcgg cgcgatcatc gcccgccgct
     3301 cgctcggcgc cgagcgcctg accgcgctgg cccaggcgct gcgcacctcg gtccggatgg
     3361 cgtgggacga ccctgccgcc tcccgcccgt acgtcctggc gcacgcccag gagatggacg
     3421 cggacgtcgc cgaccagcac atcggcctgt acgtcaacga gttcaccgcc gacctcgggg
     3481 aggacgggta cgcggccgta cgcggcctgc tgacccgggc ggcggccgag ggcctggtcc
     3541 cgccgctcgc cccggacgcc ctgcgtttcc cgtaaccgga acggaacggc tggaacacgt
     3601 acgacgagac cgccggaaca tgctgttccg gcggtctcgt cgtacgtggt gacgggggtc
     3661 gcccgctcag acgtcgagct ggtcggcgac ggcgcggagc atgccggcga ccttggcgcc
     3721 ggaggccctg tccgggtagc ggccgcgctc caggctgcgg ctgacgttct ccaggacggt
     3781 ggtgaggtcc tggacgatgg aggccagttc gtcgggcttg cggcgctggg cggcggcgac
     3841 cgagggcgcc gggtcgagga gcaccacgga aagtgcctgg tcaccgcgtt gcccggcgac
     3901 cacgccgaac tccacccgct ggccgggctt gagcgcttcg acgccggcgg gcagcacgga
     3961 cgagtgcacg aagacgtcgc cgccgtcgtc gcgggagagg aagccgaagc ccttctcgct
     4021 gttgaaccac ttgaccttgc cagtcggcaa agcactgtcc cttctcgccc tgccgccgtc
     4081 cggccgcagt gtcctggtca catatcaggg gggatgtacc cacggcgaag ctatcccatc
     4141 cgctccaccc cggcgcggag attacggggg ccggggaact accctggacc cgtgtccgac
     4201 accacccagc agaccccggc ccccggcgac cgcctcgtga agaccggcgg catcgtcttc
     4261 atcatcggcg ccctggcgac cctcgtcacc gtcgcgcccc tcttcctcgg ctccgacccg
     4321 ttcccgaccg ccgcctacct ggtctccatg ctgatgggcg tcggcttcct catcgcggga
     4381 gccgggctgg tccgccagat cgccgcacag cggcgcgaga cgcgggccgc cgtcgagggc
     4441 tgagcgccac accccgcccg gcacgctccg gctcacttcc gaacgttccg ggcgccccgc
     4501 gcgccccctt ccgcgccctc ccccgctctc cggctcccgc cgatgatggg cccgccgccg
     4561 atctgcggcg accacggacg ccgcccgctc cgctggcgga accgtttcgc ctcccggacg
     4621 gcgacgcccg tcggccaagg ctgaacagtg acggcgccgc ggttccgacc cggagcgcga
     4681 cgccccgctg agtctccgga aagcggaagg cggaacgatg tctcgcgcac aaacgacggc
     4741 tcgcgtacag gtgatccaca gctcgggtgt cctgcgatcg gccctggtgg ccctgctgga
     4801 acgcgaaagg ttccaggtca cgagcgcctc cggcttcagc agagcctcgt ccggcaccac
     4861 cggcgccccc ggcacgccag gcgctcccgc cacggtgacc gtcgtcgacg gctcctgtcc
     4921 cgtgggagcg gcccacctcg aacgccgctc cctgcaaggc tccgccaagg aacccaccca
     4981 cgccaccccc gccctcgccg ccgcccgccc gggactgggc ctcgccgggg cgggcgcaga
     5041 gcgcgccgga atcggcctcg ccggagcgag ccgggggcgc gcggccctgg tggtgctggc
     5101 cggcgcggaa caccctggcg tgctccggct cgcctacgcg gccggcgcaa tcggcctggt
     5161 cgaccgcgac gggcccgcca accacctggc caccgcgata cggctcgccg ccgggggcgg
     5221 gcggtacgtg gacgacgggc tcgcgatgag cctgctccga gcaatggaca tgccgctctc
     5281 gccacgcgag gtgcgggtgc tgagcagggc cgcgcagggg gactcggtgg cggagatcgc
     5341 ccgggggctg tgcctgtcgc acgggacggt gcggaactac atcgcttcgg ctacgcggaa
     5401 ggtgggggcg aggaaccggg tggatgcgat tcggatcagc cgggcggcgg ggtgggtttg
     5461 agggggggga ttgggggggc tggggggggc ttgggtggta cggggggggg gttgggactt
     5521 ggcgggtggg gtgggggttg ggtcgggtga ggctgaggag tggggtcggg gtgtgagtgg
     5581 ctggaaggga ggggttcgcg ggagatctgt cgggttcaat ggggggcggg tgctgggtgg
     5641 acaccatgga gggggtatga ggcattcacc cgcattgccg gaatctttga agcttgcggg
     5701 agagtgactg ggctgagtga aaccccaggt cagcgagact gctccccgcg cgtgcggggt
     5761 tggttccctc tcggcaaccg ccgctccccg cccacgccta ggtcgacgcg gtgctccggc
     5821 tccccgccgc cgaaggctcc cccagccctg ccgccagttc cccgtacaag gccgactccc
     5881 gaagtagcga ggcgtgggtc cccaggtatg gggtcgcccc gtccaagagc aggacgcgtt
     5941 gcccaggttc aggcgccgga aagtggtggc tcactgtgat gaccgtggcc gggtgggaag
     6001 cgaaggccag ctcggtcgca gcccgtgcac ctgcgtccag gtgggccgtg ggttcgtcca
     6061 gaagcagcaa tggcgtaggt gtcagccaag cccgggccaa ggcgatgcgg cggcgttcgg
     6121 atggggtgag gtgatccggg cggagggggc gggcggggtc agcggcgagc ggggtcaggg
     6181 tgaaggtgtg gatggcttcc gtgatgcgag gggccggggc gttcggggcg aggtaggtga
     6241 ggttgtcgtg gagaggggcc tcgaagatgt agggctcctg ggggacgagg acgcgggcgg
     6301 ccgtgccgag ggtgcgggcg tggcgggcgg tgtggcccgc gaggtggatc tggccgtggc
     6361 gggggggggc ggtgccggcg aggagggcca gcagggtgga cttgcccgcg ccgctcgggc
     6421 ctacgaccag gaggtgttcg ccgggttcga cggtgaggtc gaggtggtcg aggacggggg
     6481 cggcgtcggg gccgtaggcg aaggtcacgc cgcgcagggt ggcggcgggg agtgccgggc
     6541 gggtggggcg aggcccacgg gtggggcggg gtccgggggg tgagggttcc gcgcggaatg
     6601 gctcaggccc gtgtacgggc tcggggggaa gtgagggtgc ggggatggcg gggacctcgt
     6661 cgtccgcctt cccctgcgag caggcccctg gtgcccgtgg tccgtcgtcc accctcagcg
     6721 cgtgcgcctg ctcctcccgt acgtccgccg cgtccgcttc ctcccccagc agtcggtgca
     6781 gtacgaccag cagtcgtgat cccgctgccc ccagggccgt cagcagggcg ttgacggcgg
     6841 ggaggagggc ggtggtgacg taggtgaggg cggcgaggag ttcgccgggg gtgaggccgg
     6901 tggagaggag ggggggggcg gcgaggagga gggtggccac ggggaggtgg gcggcgaggc
     6961 cgagggcggt gacgcgtacg gctgaccagc gggccagggc ggaggcggcg gtggcctcgg
     7021 cggtgatgag gggggctgct tcggcggtga cgaggggggc cgcgccggtg gcggcgatgt
     7081 cgcgggcggc gtggtcggtg cggccggcga aggcggcgag gtgttcgtcg gcgtcgagga
     7141 ggtcgcgttg gcgggcggcc atggggcgga gggtggcggc gaacagggcg aggccggcgg
     7201 cgagggggat caggacgagc gggaggagcc tcggggagag cgctgccagg ccggtgaagg
     7261 cgccggccga ggtgaagagg aaggaacgta ccgtcagcag gacgccgccg gcggcgtcgc
     7321 gggcgatctc cgtctgggcg gtgaggcggg agacgcgtgc cgtgtcggcc ggggtgggtg
     7381 aggcgaccgc ccgggtcagg gtggcgcgga cgacgcggcg gaccagggag tcgcgcaggg
     7441 gctcgatcac gccgccgagc gcccggaaga ccccggcgtc ggcgaagccc ccggcgaggg
     7501 ctgcggcggc gagggcgagc agccagagga ggcccgtgcg gacgtctccg gcgaggaagc
     7561 cgtcgtccag ggcgcgggcg acggcgtagc cggtgaggaa ggtacgggcc gattcgagga
     7621 gcgaccaggc ccccagcgcc cccagcgggc ccttacggcg gcgcgcgaag gtgagggcgg
     7681 ggcgcagcag agggctgggg gcgccgtcgg tgtggcgggg gcgggtcact cgacggcccc
     7741 ggtgccggtg tcgacccggg ggtcggtgcg gatgccggta tggaggtcgg tacgcatgtc
     7801 ggcgggcagc tcggtacgta catcgctact cacgtcggta cgtacgtcgc tacgggttcg
     7861 ggcccccgtg tcagtgacgg tgtccgcccc agcgccagca tcgcccccag cccccgcccc
     7921 gaagaccgcg cggtatgccg ggtcccgcca cagaacggag tgcggccccc tcccccgtat
     7981 ccggcccccg tcgagccata cgacctggtc ggactgggcg gcggtggtga ggcggtgggt
     8041 gatggtgagg cgggtgccgg gggtgtcggt gagggcgcgg gcgacgaggt gggcggtgac
     8101 ggtgtcgagg ctggaggtgg cgtcgtccag gatcaggagg cgggtggggc gggtgaacgc
     8161 ccgtgccagg ccgaggcgtt ggagttcgcc gccggagagg ggggcttcgg ggaggggggt
     8221 gcgggggccg tgcgggaggc ggtccgtgaa ggtgtcggcg gcggcgcggc gcagggctcg
     8281 gcggagttcg ggctcgggca gggggccgca ggcgacggcg tcggcgatgg tggcgccgaa
     8341 gagggccggg cgttcgaagg cgtacgcgac ggcgtggcgc agggtgtcgg cggagagggt
     8401 gcggaggtcg gttccgtcga ggaggacggt gccctggacg gggtcggtga ggcggccggc
     8461 caccgccgcc agcagggact tgccggagcc ggacgggccg acgagggcgg tggtggtgcc
     8521 gccggggagg gtgagggtga cggagtcgag gagcgggacg ccgtcgcggg tgacgtggac
     8581 gccgtgcagg gcgagggtgc cgtcgccgtg cgggggcagg tcgcgcgtcc cgtggggggt
     8641 gggcggcagg gcggtgacgg tctcgacgcg ggcggtgccg gccttggcgc gtacccagct
     8701 gttgagggcg ccggccaggg ctccggctcc ggcggcgagg acggcgtagc gggagagggc
     8761 gaggaggtcg ccgggggtga ggtggccggc gacgaggcgt acgccgccga cggcgaggac
     8821 ggcggcgacc aggagcggca tcagcgcgcc ggagaggccg gcggcgcggc cctgcacgcg
     8881 ccaggtgcgc tcgccggccg cgcgcatccc ggccagcggg gcgaggacgc ggcgttcctc
     8941 ggcccggacg gttccggcgg cggcgatggt ggcggcgccg gacagggcgc cggtcagcag
     9001 gcgggccatg cggccctgtt cctcctggta cgtggtgagg gcggcgcggc cgtcgcggag
     9061 cagggcgcgc aggatgagga ggaggagcgg gacgccgcag acgaaggcgg cgccggccca
     9121 cgggtcgacg aggaagagcc cggccaggcc gccgaggggg gcgaggccgg cggcggcagc
     9181 ggtggcggcg gccacggggg cggttccggc gtcgagggcg ttggcggtga ggcgggtggg
     9241 caggccggtg ccggtggtcg cggcgggggg cgcggcgagg aagccggcga gcgcgcggcg
     9301 gcgcagccag gccgtggtgg cggcgccggt ccggccgccg gtgcgggcga cgagggcgtc
     9361 cgtggccacc tcggtggcga tcagcgcggt gcacagcagg acccaggacc cggcgtcggc
     9421 gcgggcgatg agcaggtcga cggcgcggcc gagggcgagg ggcagggtga cggcggcggc
     9481 ggcgccgagc gcggtggccg cgaggacgag ggccgcgggt cccctgcccc ggcgtaccgc
     9541 ctcccgcagc aggcgcccct cggcgggcgg cggggcgggg gtggcgcggg cccgggcggc
     9601 gtcggcgggg gcggcggtca tggctgctcc gttcgggcgg gcgagcgggc gggggctgtc
     9661 cgggcgggcg cggaacgcgg gaggtcccgg gcgctggggc gcccgggacc aagggttgtc
     9721 gcacgcgccc ggcccgcagg gggccgggcg cgcggcggac agccgggttc agccctgcgt
     9781 cacggggtgc agagggtgac gctcagcgag ctgtactcgc agatgagcag ggagatctgg
     9841 ctgccggtgg cgaggtcgcc caccgcctcc tcctgcgggg tgtccatcgc ctggaggtcg
     9901 agaagcgcca tgacgtactc cttcgtgtcg agcggtcgga cgaccgccac ctgggaaaac
     9961 gagtggtgct ggtggtgctg ggtggtgcgc gaccctgggt tcagggccgg tctgtgggcc
    10021 gccggagcgg cgggaggaag ggcaggtgcg cggcgggttc gccgtgggtc gctgccaggg
    10081 cgagcaggac gccggccgtg ccggtggaga ggtccatcga caggcgggtc agctgttcgc
    10141 cggggtgggc gaggtgccct tggtaggtga gcgcgtgcca gtccagcagg gcggtctggc
    10201 gggtcaggag ggcggtgcgg gcggcccggt cgccgggggt ggtggtgcgg gccaggtgga
    10261 ggaggagtcc ggcgacgccc cggaagaggc ccggctggat gtagaaggcg gagccggtgg
    10321 cccgcaggag agcggtccgg gcctcctcga aggcggggtc gggccgccgg tccaggtagt
    10381 cgtcgaggac catcgcgatg cccgcgctcc cggagccgag gtacggcatg gtccgccggg
    10441 cctcggagac gacgagcgag ccgtccggcc ccggcacgca gcggcccagc tcctcgcgca
    10501 gcgcggtggc ggcggtgtcg agcagggcgg gttcgccggt acgggcgtgg cggcgcaggc
    10561 agagcagggc ggtgccggcc gggccgtgca gcagtccggc cttgccgccg ggggcggcgg
    10621 ggcggagtgc ggcggcctcg gcgcggtcgg cggcctggcc gagggcgggg tcgtcggtgg
    10681 cgtcggccag gtcgcgcagg gccagggcga cgccgggggc gccggagtgc aggccggggc
    10741 cgagtgcgtc gaggggttcg gcggcgacga ggtgggcgag gcgcagggcc tcctcgcggt
    10801 ggccgaggcg gtccagggtc caggcgatgc cggtgaggcc gtcgtagaag ccggtcgggg
    10861 tgccggaggc ggggtggcgg gtggtgcgga tcagccattc ctcggcctcc tcgcagcgga
    10921 cgccgacggt gtggagggcg tgcaggacgc cggcggcgcc gtagccgtac gactgtcccc
    10981 cggccggggt ggcgaactgg gcgatgtcgc ccgggaagta gcggtcgtcg cggccggggg
    11041 tggcggaggc gagcagggcg gccaccatcg agtcgcgggc ggcgggccag tcggtggcgg
    11101 acaccggtgg ccggccgcgt gacggcccgg cctccggccg tgccgggccg gcgagttcgg
    11161 tgaccgcctc gtcgaagagg gcgcggtcga tgccgtaccg gtccgcggca aggccggcga
    11221 ggtgggccgc cttgtcgcgg tcgaggggca gcagggtggt gagcgggacg aagagggcga
    11281 ggcggaggca ggccagggcg taccggtcga cctcggtgcc gcgcaggtgg ggcggggcga
    11341 cgaaggcggg gttggcgacg atctgcgggc ggcgctcggc ggccggggtg gcggcctcga
    11401 agtccagcag ggtgacggag agctggtccg gcgccaccat gatgttgttc atgtgcaggt
    11461 cgccgaaggc gatgccccgg gtgtggagcg cctcgacggc ctccgtgacg agctggtggg
    11521 tgcgcagcgc ccaggcggtg tgctcggcga gggcttcggc ggccggctcg gcggcggaga
    11581 gcgggaagcg gcgggcgaag acggtgttga gcggggtgcc ggggatgaac tccatggcca
    11641 ggaagcggtg ttcgcccacg gtgtgcagtc cgtgcacgcg ggggacgcac gccagccctt
    11701 cgagggcgcg cagggccgcg tactcccgct ccaggcgggt gaccgcgtcg gccccgtcgg
    11761 cggcgagccc ggcgtgcggc cggccctcct tgagcaccac ggcctcaccg gtctcccggt
    11821 gcgaaccggc gtacaccccg cccccgttgg agaagtgcag ggcgcgttcg acggtgtacg
    11881 ggagatcggt cgtgccctgg gcggcgcggg cctcggcgtg cgggcgcagg aagtcgggga
    11941 gttccaccca gtcggggagg cggaaggcgg ggccgcgggt gtccgggacg aggcggccgg
    12001 ccgggtcggc caccgccggg accagggagc cgtcggcggc gcgggtgaag cggggcgcga
    12061 aggcgccgta gcggacgtgg accgggccct cgccccagcg caggtcgctg aggacgaccg
    12121 gtcccgcgct gcccttgagg gcgtcggcga gttcggcggc gagttcgccg caggcggcgg
    12181 tggtggccgg gtagacggtg acgaacttgc cgctgccggc gcgatcggcg tacttggtgt
    12241 tgcggtggag cagcagggcg ggcccggcga ggaacttgaa ggcggtggcg cgctcctggc
    12301 agatcccggc gaccgtctcc aggacctctt cggcgttgtc cggcgtcgcg gagacgtgga
    12361 tcttccagcc ctgggcgggg agttggcgcc cggcgggggc gagcgagaac cagtcaccgc
    12421 gctcggcgct ctcccagccc tcgggaacgg ggcgccgggc gagggcgtaa cggtgaccgt
    12481 cgctgccgtt ggcgttgccg ctgccgtcgg ccgtacggcc ggcccggcgc ggggtgtcgt
    12541 agaaccagcg gtcggtaccg ctgtagagcg cgtactccgg attcaccggt ccccctcgcc
    12601 gtctgcgttc ccgtgtcgtg ccgtgtcgtg ctgtgcgtcg atgacgggtt ccacactgcc
    12661 cgtggccggg tggtgccggt aagtaacgcc tgtcatcggc gagttgtggg aaacgcatgg
    12721 tccgaacggg tcatggcgga cgggctcgga gcgtgctgcg agggggctgc cggtggctgc
    12781 cggaagcgat tgcggaggtc aggaggcggg ggtcagggcc tcttccagct cgtccaggat
    12841 ctgctgggcg gcggtgtagc cgatgccctg gatccacagc tcgtcctcga ccttgtggac
    12901 ggcgccggac ttgacggcgt ccagggagcg ccagagggcg gacctggtgg tctgcgtctc
    12961 cttggccttc tccgggtcgc cgtaggtggc ggtgaagacc acgtcggcgt cggccaggtc
    13021 gatcttctcg gggctcacgt cgtacgagaa gccgtcggtg gccttgtcgg tgatggcggg
    13081 gcggccgagg ccgacgtcgg cgaggagggt gccgatgtag ttcttcttgc cgtagatgcg
    13141 gatgtcggcg ccctcgacga agcggaccac gttgacctcg gtcttctcgg cctcggccgg
    13201 gccgccgacc gcctcggtga cctcggcggt ccgcttctcg taggcggcgg tggcgcggtc
    13261 ggcctccttc tgcttgccga gtgcctcggc gtgcacctgg aagttctcct tccaggggta
    13321 gccggtgttc tccgtcatca cggtggcggc gatcttactc agctgggcgt aacgggcctc
    13381 gtcgcggacc ttggaggtga ggatcaggtc gggctcgagc gccgcgatcg cctccaggtt
    13441 gggctgggcg atgacgccga cgttctcgat cccggccagt tccttctccg gcaggtagct
    13501 ggcgaacccg ccggcggcgt cggagcgtac ggcgccgacc ggcttcacgc cgagggtgag
    13561 cgcggagtcc agctcggcgg tgtccaggac gacgacccgc ttcggcgcct cggggacctc
    13621 cacctcgccc atcgcggtct tgacggtacg ggtggctccc gcgtccttgc ccgcgtcgtc
    13681 ggcggtcttc tcaccggagc cgcaggcggt gagggtgagg gcgagcgcga gggcgccggt
    13741 ggcggcgagg agcggacggg cggtacgtcg ggtcatggcg tggccctgct ttcttctcgg
    13801 gtggggacag cgggttccgg cgccggccgg gcgtcccagg gcgcgcccgg gacgacgagc
    13861 ggggagccgg tgacggggtc cgggacgacg acgcactcca ggccgaagat ctcccggacc
    13921 aggccggcgg tgacgacctc ggcgggggcg ccctcggcga cgacgcggcc ctcccggaag
    13981 gcgatgaggt gatcggcgta acgggcggcc tggttgaggt cgtgcagaac gaggacgacg
    14041 gtgcggccct gctcgcggtt gaggcggcgg accaggtcga ggacctcgac ctggtgggcg
    14101 aggtcgagat aggtggtggg ctcgtcgagc aggagcaggc cggtctcctg ggcgagggcc
    14161 atggcgatcc agacgcgctg ccgctggccg ccggagaggg cgtccacagg gcggtcggcg
    14221 aggtcggtgg tggcggtgcg ggccatcgcc tccgtgaccg cccgctcgtc ctcctcggac
    14281 cactgctgcc accaccgctg gtgcggctgg cggccgtgcg ccaccaggtc ggccacggtg
    14341 atcgcctccg gtgccaccgg ggtctgcggc agcagcccga tctgccgggc gatctggcgg
    14401 gtgggcagcc gggccagttc cgcgccgtcg agcaggacgg cgccgccggc ggggcgcagc
    14461 agccggccga gcgcccgcag ggtggtggac ttgccgcagg cgttgggccc gatgatgacg
    14521 gtgacccggc cgtcggggat gtccaggtcg aggccgggga cgacggtgcg gtcctcgtag
    14581 gcgagggtga ggtcccgggc ggtgaggcgg gcggcggggc gggtcatgag gtgcctccgg
    14641 tggcgcgggg gccgtgtcgg gtgacgagca gccagatcag gtacggggcg ccgaccgccg
    14701 cggtgagcac ccccaccggc agttcggtcg gcgcgaagag gcgacgggcc agcaggtcgg
    14761 cggcgaccac ggtcaccgcg cccgccagcg cggagcagac cagcgggatc tgcgcggtac
    14821 gggccagccg ccgggcgatc tgcggggcga gcagcgcgac gaagtcgacg ggcccggccg
    14881 cgccggtggc gaccgaggcg aggaccaccc cgacgaggac gaggccgaga cgggcgcgcc
    14941 ccaggcgggc gccgagggag gtcgcggtgg cgtcgtccag ggtgacggtg cgctgggcgc
    15001 gggcggccca gaccagggcg ggcagggcgg cgagcagggt ccagccgacg agggcggcct
    15061 ccggccaggc gcggccgttg agggaaccgc tcatccacac ctgggcctgc tgggccacgg
    15121 tctggtcgcc cttggtcagg aagagcgtgg tcagcgcccg cagggccacc gcgaacccga
    15181 ccccgaccag cacgaaccgg gtggcctgga gcccgccccg ccaggcgaag aggtagacga
    15241 gcagcgccgc gaggagcccg ccgcccaccg agatccaggg cagcacggtg tacgaggtga
    15301 cgccgaaggt cagcgcggcg accgtggcgg cgctcgcgcc ctggctcacc ccgatcaggt
    15361 ccgggctggc cagcgggttc cgggcgacgg tctggatcag cgcgcccgcg atcccgaacg
    15421 ccgccccgac gtagagcccc gccaccatcc ggggcagccg cagctccccc accaccagcg
    15481 tgtccggcga gggacgcccg agcagcacgt cgaccaccga cccgggcgcg acgaagctct
    15541 cgcccacact caggtacgcc acgcacacca cggccagcac gcccgccagg acggcgccgg
    15601 tcgccacggc ccgcacgggg acgaggaggc tggcgggccc gacgcgtacg gggacgtacc
    15661 cggcgggtcg tacgcgggcg ggttccggcc ccgccttcag cgccacgctg ccgccgctca
    15721 cgcggtcacc gccctgctcc gaacgagcgc caccaggaag ggcacgccga tcagggccgt
    15781 catgaccccg gcggggacct cgcccggcgg gaagaggacg cggccgacgg tgtcggaggc
    15841 gaggagcatc acggggccgg tcagggcggc cagcgggagg acccagcggt ggtcgccgcc
    15901 gaccaggtgg cggacgaggt gcgggaccgc gaggccgacg aaggcgaccg gcccggcggc
    15961 ggccaccccg accccggtca gcacggcggc tccggcgccc gcggtgatcc gtacggccgc
    16021 cacccgctgc cccagcccct tcgccacgtc ctcccccagc gccagcgcgt ccagcccccg
    16081 ggccgacgag gcgaccagcg ccagccccac cagcaggaac ggccagacct ggacggccac
    16141 gtcggcgccc cggccctgga gcgcccccac gttccagaag cggaactcgt ccagggcact
    16201 ggaactggtg gtcagcacgg cggtggtgac cgagaccagc agggcgttga tcgcggcgcc
    16261 gctcagcgcc agcttgaccg gggtcgcgcc gccccggccg cccgccgcga ccgcgtacac
    16321 ggccaccgcc gcgagccccg cacccacgaa ggcgaaccac acgtacccgg ccagggtgtg
    16381 cacccccgcg aaggcgatgg cgaggaccac cccgaccgag gcgccctggc tgatgccgag
    16441 gatgcccggg tccgcgatcg gattacgggt gatgccctgc agggcggtcc cggcgacggc
    16501 gagcgcggcg ccgaccatca cgccgatcag cgtgcgcggc agccgcatct cccggaccac
    16561 ctcggcgtcc gggcccgtgg ccccctggaa cagggcctcc acgaccgttc cgggcgccac
    16621 cgtacgggcg ccgacggcca ggctgaggac gaccgcgacc agcagcgccg ccagggccgc
    16681 caccgtccag gccgcccggc gtacggcgct gtcccggcgg ggccggggcg cggtgggcgg
    16741 ggccttcgcc ggcgacgggg cggcgggtgg ggcggggggc atcgggtcct ttccgggcgg
    16801 tctgcggggc gccggccggg agcggacacc acgacacacc gccccaattg cccgttctgc
    16861 gccgggactt aggcttggct aagtgtacgg ccgccggggc tgcacaatgg agggatgccc
    16921 gagcacctca cctccgccgc gcccgctccc tccgaccccg ccgtaccggc cgcacgtccg
    16981 gttccgggcg gggcggggcc cgtcgtcggg ttcgacctcg acatgacgct gatcgactcc
    17041 cggccgggca tcggcgccgc ctaccgtgta ctcgccgccg agaccggcgt ccccatcgac
    17101 gtcgacctgg tcgtctcccg gctcgggccg cccctcgaaa ccgagctggc ctgctggttc
    17161 ccggccgagc aggtccccgc cgccgccgcg cgctaccgcg aggtctaccc gaccaccgcg
    17221 atagccccct cgctcgccct gcccggcgcc tcggccgccc tggaagccgt acgggcccac
    17281 ggtgggcgct cgctcgtcgt gaccgccaag aacgaggagc acgcgcggct ccacctcgac
    17341 cacctcggcc tccgggccga cctcgtcgtc ggcagcctct gggccgaggc caaggggggt
    17401 gcgctgcgcg cacagggggc caccgtctac gtcggggacc acgtcggcga cgtgcgcggt
    17461 gcccgggccg ccggggcctt ctccgtggcc gtcgccaccg ggggctgcac ccccgacgaa
    17521 ctccgcaccg ccggcgccga cctcgtcctc ccggacctga ccgccttccc cgcctggctg
    17581 gcggagttcg cccgctgatt cgcctcgggc gccggccggg gtgtggctgc gccgcgactg
    17641 ggggtgcctt cgcctgcgcc cggcccccga ttggcctcaa gcgccggccg ggctggggtt
    17701 tggtgtggct gggctccgcc cctgcgtgcc cgcccgtgcc cctgcgggtc accgatggcc
    17761 tcaatcgccg gccgggctgt cggttgccgg gctccgtctc gaccgtgccg gtcaccgatt
    17821 ggcctcaaac gccggccggg ctatgagggt cgcgatgcgt tcgccggctg ggtcgggcgg
    17881 ggccgcaccg gggtacctcc tcacaaactg ccaggtgcgg ggtcagtcgc ttcaaggcgg
    17941 ccgagcacgg cagtttgctg cgggggcacc ccggcacgac cccgcccttc cgtctcgtcg
    18001 gcgtcgttcc gccggtggga gggagaagac aaggccgtcg cctattgatc tttgtggcga
    18061 gcgagagcga ggacggtggt caccgtggag aggccctgta tcggtgacgg cctcatccca
    18121 ccctccggca gttggccgcg tacgagaccg tggggtgggg acgggtcggg gtgcccccgc
    18181 agcaaactgc acacacggcc gccttaaagc gactgacccc gcaccatgca gtttgtgagg
    18241 aggtaccccg gcccggcccc accccaccca cgcaccggag aaaccgcgaa ccccatagcc
    18301 cggccggcga ttgaggccat ctctgaccgg cacggtcgag acggagcccg gcacccaaca
    18361 gcccggccgg cgcctgaggc catcagtgac ccgcagggtc gagacgggca ggtggaggcg
    18421 gagcccagcc accaccccat cccagcccgg ccggcgtttg aggccagtca gtgaccgggc
    18481 acgggcaaca accggcaccc caagtcgcgg cgcagccacg ccccagcccg gccggcgctt
    18541 gaggccaccg ggaccggcag gggcgaggcc ggtagatcgg ggcggagccc ggcaagcaac
    18601 agcccggccg gcggttgagg ccgatcgggg accaggcaca ggcgaaggca cccccagtcg
    18661 cggcgcagcc acatcgcggc caagcagata ggcgaagccc agccccgccg gaggccctga
    18721 gtaccggcgg gcccgcccgc ccacgtagcg tgcaaccccc gcgcgcaggt cggtcgcgca
    18781 cgaacggggt aggcacccct cgacccgtag ggcaccgggt gccgcgagga ggaacgatga
    18841 agcaaccggc tcggacagcg ggcggggccg tggccgagga ggcgcggacg gtggagggtg
    18901 tcgaggggga cgggcccgtg aagggtgagc cggggcggac ggtggagtgg tgggtggcgt
    18961 tgcggcggac gccgggggcg ttctggcggg acgacatctc ggacttcgcg gcggcgctga
    19021 cctattacgc gatcctcgcc gtgctgccgg cgctgctggt ggtggtgatc gctttcgggc
    19081 tggtgagtcc ggacacggcg gagcggttcg tggggcaggt gacggcgtgg gcgccgggcg
    19141 gctcgggcgc ctcgttgcgc gaggtgctga cgcgggtggt gcgggtcgac tcgacggcgt
    19201 ggacgctgct ggtgacgggc ggggcgagcg cgctctggtc ggcctccagc tacctggcgg
    19261 tctcgcggcg cgcgctgcac cgcatgtacg gggtacggga ccggcgttcg ccgtggggca
    19321 aggcgcaccg gatcgtggcg acggccctgg ccctgctggc gctgctgctg gtcagttcgc
    19381 tgctgctgat gctgaccgag ccggtggccg agtcgatcgg gcggctgctg gggctggacg
    19441 ccggggtggc gtgggcgtgg agcgtgctgc gctggccgct gctgctgtgc ctggtggcct
    19501 gtctggtcgt ggtcgttttc cggaacggcc cggtggccgc ccgtcggcgc gcccacagca
    19561 tcccgggcgg cgtcctcgcc gcgacgctct ggctgaccgc gtcggcgggg ctggcgctgt
    19621 acgcctcggt gctcagtacg tacagccgtc tctacggctc gctcgcgggg atcgtcgtct
    19681 tcctggtgtg gctgtggctc tccaacgtcg cgctgctgct cggcgcccag ttcacggcgg
    19741 agttgtgccg cgcggcgggg ggtccgggcg caccggcctg ccacccggag ccggccgagg
    19801 aggtggccgc ccagggcgcg tcggccggcg ccgaggacgc cgaggacgcc gaggagacca
    19861 gggagcacgg gcgggcgccc accggtgcgt gatccccttc cgcttttcgc cctggcgggg
    19921 atggagcgtg tcgtacgcgg gcaaggcggg tgatcccccg cagagggtgc gtacatcccg
    19981 ccagggactg gcctgaactg gtcacttgac atatgacaca tggtcagttg ggccctatcc
    20041 atgactccct ggcgaccgtt actttacaaa gtgtgattac tgaacgagag attccgctcc
    20101 gccacggctc catctccgcc tccgtttcca ccgccgacga cctgctcttc gcgacacgcg
    20161 gcgaagaaca cctgcgctgg cgggagctat tcagcacgga ggagttcggc caccgggact
    20221 tgccacaccg ggaaagggtg gagttgtcct atcggcgctt gcgtaccgtc gccgccgcga
    20281 tacccgatcc ccgcgcgctc gccctgagcg cgccggcgct gaccgcgctc cacgagtggg
    20341 cgggcccggc cgatcccggg atggccacgc tggcctccat ccactacaac ctcttcctgg
    20401 gcagcctcct cgaccacgac cacgcggagc gggacctgga gccgtggctg cggatggacc
    20461 ggatcggcac gttcctgtgc accgaggccg agcacggcaa cgacgcggtg aacatggaga
    20521 cgaccgccga gtacgaccgc gcctctcgtc agttcgtcct caacaccccg ggcccggggg
    20581 cggccaagtg gatgcccaac acctcgctga ccggcggtcc gaaagacgcc gtggtcgccg
    20641 cccggctgct ggtcgacggc cgtgacctgg gcatcttcct cttcctcacc ccgctcagca
    20701 acgagcgggg ccacctgccg ggcgtcagcg tcgagcggct gccgcacacc tccggcgcgc
    20761 ccgtggacca ctgcgccacc cgcttccacc acgtgcggct gccgcacagc gcgatgctcc
    20821 agggcgacca cgggaggctc agccccgacg gggagttcga gagcaccctc ggcagccccc
    20881 gcatccgctt cctgcgctcc atcggccggg tgtcgatggg caagctctgc atgtccggct
    20941 acagcctggg cgccacccgg caggcggtcg cggtcgccgt acggcacggc tccacgcggc
    21001 tgacctccgg catgaccaag ggccgccggg tcccgctgat ggcccaccgc agccaccacg
    21061 agccgctgct cgacgccctc gccaccacgt acgcggcgac gctgctgcac cgctcggtgg
    21121 tacgccagtg ggaggtggcc gaggaggccg agcgcgagga ggtcgaccgg ctggtcgcgg
    21181 tgaccaaggg gtggatcacc tgggccgccc gggagaccat gacgacctgc cgtgagcggt
    21241 gcggcgccaa ggggctgctg ctgacgcagg gcatcgcggg ccagctcgcc gccaacgagg
    21301 gcaccatcac cgccgagggc gacaaccagg tcatctgggt caaggccgcc ggtgagctgc
    21361 tgatgggcgg gttcaccccg aagcccccca gcgagaccgc gcccgagcag cggtccctgc
    21421 gcgacggtac gcacctccag gacctgatgg cggacgtgga gcggatctgg cacgagcggg
    21481 cccggacccg gctgcgcacg ggcggcgtac gcggcaaccc gatggcccgc tggaacggcg
    21541 cggtcacccc ggcgctggaa ctggtcgccg cccacgcgca ccggctggcc ggggaggcac
    21601 tgctggaggg ctccgaccgg gtcaccgggg acgaggccga gcgcatccgc gacctgcacc
    21661 gcctcttcgc gctgcgccag gtggcggcgc acagcgggga gctgctggcc ggggagcggc
    21721 tgacggcgga gcaggtgcgg cggctcccgg acgaggtcga gcgggtcgtg gcggacctgg
    21781 agccccacgc cctcgccctg acggaacgtt tcttcgtacc ggagcaggtg cccggcagcg
    21841 accccgcggg cctggtcgag accgcgggcc tggtcgaggc cgcggacctc gtcgagcccg
    21901 cgcccgaggc cgtcgccgga gccgtccccg ccggcgcgga gtcccgtgcc ggcgggctcc
    21961 gggagagcga gccggacgcg gcatgacggg ctgaggcgca cgacgacggg acacgggacg
    22021 gcccgccgtg cgtgggcacg acgggccgtc ctcgcgtctc tcgtcctccg ggcggcacgc
    22081 cggccggagg ctccgggtca gacccggaag atgtcgagga aggagctcca gaagcccttc
    22141 ctgcgaccgc cgccgtccga ggaggccggg gcggtgtgct gcggctgcgg ggtggcgggt
    22201 gccgcctgct gctgcgggat gccccggttc tggagggccg cggccatccg ggtggccggg
    22261 gtggggctga aggcgaccgg cagggagacc agggcccggt ggaagggtcc cgggcgccac
    22321 tggaggtcct cctccgggac gccgagcgtg aggtccggca gggcgttgag gatcttctcg
    22381 accgcggtga ccgcgatgac ctgcgccggg tccttggccg ggcaggcgtg cgagcccgcg
    22441 ccccaggcga ggtgcgcgcc gcgacccgcg ctgcggcggg cctcggcgag ggccgggtcg
    22501 ctgttggcgc ccgcgaagga gatcaggacg gggctgccgg cgggcgcgat gacaccgttg
    22561 ccgaagtccg tgtcctgggc cgggta
//
