LOCUS       NZ_VOGX01000034        41098 bp    DNA     linear   CON 15-OCT-2024
DEFINITION  Streptomyces albidoflavus strain 77
            scaffold11_cov50_3627731_4779920, whole genome shotgun sequence.
ACCESSION   NZ_VOGX01000034
VERSION     NZ_VOGX01000034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 1152190)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   2  (bases 1 to 1152190)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUL-2019
            Assembly Method                   :: SPAdes v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 36.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007896905.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 04:20:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,551
            CDSs (total)                      :: 6,456
            Genes (coding)                    :: 6,343
            CDSs (with protein)               :: 6,343
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 34 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 8 of 113
            Pseudo Genes (multiple problems)  :: 8 of 113
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:41:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 831483
            Orig. end                         :: 872581
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOGX01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..41098
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="T3PKS"
                     /region_number="3"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     cand_cluster    1..41098
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..41098
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="False"
                     /core_location="[20000:21098](-)"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      complement(20001..21098)
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     gene            351..1298
                     /locus_tag="FRZ02_RS21975"
                     /old_locus_tag="FRZ02_21975"
     CDS             351..1298
                     /EC_number="1.13.11.16"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_process="GO:0008152 - metabolic process [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008412599.1"
                     /locus_tag="FRZ02_RS21975"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21975"
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="WP_146582375.1"
                     /transl_table=11
                     /translation="MTLALVTMSHSPLLEYADPPAEVKDAVQGAFSAARTFVRAYDPTL
                     VVSFAPDHYNGFFHDLMPPFCIGYAAVGVGDYGTTAGPLNVPAGRAAELAQWVAERDLD
                     VAVSRRMEVDHGAVQPLEILFDGIDTVPVVPVFVNGVATPFVSMRRVRELGEAIGGYLA
                     GLEGERVLVIGSGGLSHDPPVPQWATADDTARAMLLDGRHPTAAARDARQQRVIDTARA
                     FAAGTAPIQDLNPDWDRALMATFASGDLTPADAMTPDRMAEDAGNSAHEVRTWLAAFAA
                     LGAAGPYEVTHSFYRPIKEYIAGFGVMTARSVAG"
     gene            complement(1331..2125)
                     /locus_tag="FRZ02_RS21980"
                     /old_locus_tag="FRZ02_21980"
     CDS             complement(1331..2125)
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470977.1"
                     /locus_tag="FRZ02_RS21980"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21980"
                     /product="DeoR/GlpR family DNA-binding transcription
                     regulator"
                     /protein_id="WP_003946603.1"
                     /transl_table=11
                     /translation="MTEDAPPLIPDQRREKLLKHLRRDGVLSVQQITQLFGVSHMTVRR
                     DIAELERQGLVFTVPGGVRIASQVRSEPSHQAKTQVEQPQKEAMASRAASLVEDGMTLY
                     LDAGTTLLAAVPHLVHHERLTVVSNDFSTVDRLMTEAPHLEIIHVGGQVEAANRSTVGR
                     LAAATLRHLALDMAFISTSSWDLLRGVTTPSDAKVEVKRAALDSSRSAVLVAGSSKFGT
                     FGKYRVAPLADFDAIITDSALTEAAAEGVRDSGPELHLAGPA"
     gene            complement(2221..3579)
                     /locus_tag="FRZ02_RS21985"
                     /old_locus_tag="FRZ02_21985"
     CDS             complement(2221..3579)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015128 - gluconate transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0035429 - gluconate transmembrane transport
                     [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946602.1"
                     /locus_tag="FRZ02_RS21985"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21985"
                     /product="gluconate:H+ symporter"
                     /protein_id="WP_003946602.1"
                     /transl_table=11
                     /translation="MSTDIQHLLLGLAAVVVLILLITKAKLHPFLALALSAIGLGLASG
                     IGPGDTVTHFQDGFGDALKSVGPTIGLGTLLGGILLGSGGADRIATVFIGARPVKWIPT
                     AITAAALLIGMPHLFDVSFVMLVPLVYAVAKRTGTHLLYVGLPMAAGLYISHGLLPPHP
                     SPTLAVSAYDASTGLTILYGLIIGIPIAVLTGPVLTRYASRWFGPAPDLDKGPVPDAGP
                     APENQRRPASFTLALITVLLPPVLMLIGTIGTSATREGTAPYTVFEACDSPVLSLLVAV
                     LFAFFALGVRSGFGLGQIQKMAAKGLGPVGGIVLILGAGGGLKAMLTATGIDKIISDYA
                     VDWAIPPLVLAWLVAALLRICLGSATVATAAATGIVAPLVGAYPGLSPELLVLATASGA
                     VMLSHVNDSGFWLFKEYFQLSVPQTFRTWTLMLSLQSLLSLGGVLLLSLFVGG"
     gene            complement(3576..4979)
                     /locus_tag="FRZ02_RS21990"
                     /old_locus_tag="FRZ02_21990"
     CDS             complement(3576..4979)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639422.1"
                     /locus_tag="FRZ02_RS21990"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21990"
                     /product="homoserine dehydrogenase"
                     /protein_id="WP_003946601.1"
                     /transl_table=11
                     /translation="MNFLHLFAPGGDRTVRYALSGAGGGFARTLLAQTLRIPRLRPAVL
                     CDQDVAGLRAMLVELGYDASQLRICGDARAVRDAGQDGHLALVADGDLLIAGDWDILVE
                     ATGSPAAGYEMARQALTGGRHVAMVSKEVDSVAGLHLAELARTHGSVYTTADGDQPANL
                     IGLVSWAETLGLEIVAIGKSTEYDLVLDPAAGTVTQLDTTVPAPELAGLLDLGDDVRST
                     LAARAAAVAALPTGATADYCEMAVVATSTGFRPDTERLHYPVARIAELADVYALREDGG
                     VLRRPGAVDVFSALRLPGEASFAGGVFVVVRTGDPVTWETLRGKGHVVSRDGKYAAVYL
                     PYHLMGVETPVSLLSAVLDQRPSGGTDPRGHAVLAGRAERDLPAGTVLTMGGHHHDVTG
                     VQAVLLRDEDTPAGTAPLYLAAHATLAADVAAGELITVGHLADADAALLDAWTAGRAAR
                     PATGPVNGS"
     misc_feature    complement(5091..5104)
                     /note="TFBS match to PerR, Peroxide regulator, confidence:
                     weak, score: 15.84"
                     /tool="antismash"
     misc_feature    5129..5145
                     /note="TFBS match to HexR, Glucose-responsive regulator,
                     confidence: weak, score: 15.66"
                     /tool="antismash"
     misc_feature    complement(5130..5141)
                     /note="TFBS match to CcpA, Catabolite control protein A,
                     confidence: weak, score: 15.14"
                     /tool="antismash"
     misc_feature    5130..5145
                     /note="TFBS match to ColR, Phenol-responsive regulator,
                     confidence: weak, score: 18.02"
                     /tool="antismash"
     misc_feature    complement(5130..5145)
                     /note="TFBS match to CopR, Copper-responsive regulator,
                     confidence: weak, score: 16.88"
                     /tool="antismash"
     misc_feature    5135..5144
                     /note="TFBS match to ToxT, Regulator of MSHA biosynthesis,
                     confidence: weak, score: 14.15"
                     /tool="antismash"
     misc_feature    5136..5149
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 16.43"
                     /tool="antismash"
     misc_feature    5137..5151
                     /note="TFBS match to CodY, Regulator of stationary phase
                     and virulence in Gram-positive bacteria, confidence: weak,
                     score: 14.86"
                     /tool="antismash"
     misc_feature    5139..5152
                     /note="TFBS match to MogR, Repressor of flagellar motility
                     genes, confidence: weak, score: 12.49"
                     /tool="antismash"
     gene            5211..6479
                     /gene="otnK"
                     /locus_tag="FRZ02_RS21995"
                     /old_locus_tag="FRZ02_21995"
     CDS             5211..6479
                     /EC_number="2.7.1.217"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /GO_process="GO:0005975 - carbohydrate metabolic process
                     [Evidence IEA]"
                     /codon_start=1
                     /gene="otnK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894147.1"
                     /locus_tag="FRZ02_RS21995"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21995"
                     /product="3-oxo-tetronate kinase"
                     /protein_id="WP_067410201.1"
                     /transl_table=11
                     /translation="MPTLGAIADDFTGATDLATMLVSRGFRTLVAIGADAVDPEASAEA
                     DAVVVALKSRTAPVEEAVADSLAALRALRAAGCRRYYFKYCSTFDSTPRGNIGPVADAL
                     LEAVHADRTVVVPAFPATGRTVRDGLLYVHGEPLDRSPMRHHPLTPMTDASLARLLRPQ
                     TRHPVRQIPLATVRAGAAELRAAVDAPEASGALLVVDAETDDDLRTVSAATAHLGLVTG
                     AAGLALGLTGPRPGAARATPASSPGDPAAVLSGSASSTTRAQVAHGRAHLPHRKLDVAA
                     LRRDLPATVAGLAAFAREQWRLDPARPPLFYAVDDLADLERTTPPGEAPASALIEEALA
                     ALAVALVDDGARRLLVAGGETSGAVVTALEVRGLAIGAPLAPGVTWARAETGTGGGRNI
                     DLALKSGNFGGTDIFTEAWSALV"
     gene            6476..7114
                     /locus_tag="FRZ02_RS22000"
                     /old_locus_tag="FRZ02_22000"
     CDS             6476..7114
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946599.1"
                     /locus_tag="FRZ02_RS22000"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22000"
                     /product="class II aldolase/adducin family protein"
                     /protein_id="WP_003946599.1"
                     /transl_table=11
                     /translation="MSDVRAGLAAAGAHLAALGLSPGSSGNLSVRDGGLLYITPTGADL
                     SRLDPDGLSVLDRDGTHLEGPRPSKEFPLHTALYRRDAATRAVVHLHSRHAAALSCLPP
                     WSGRSAVPPLTPYFVMRVGQTPLLPYAPPGDPGQAKELERLPFPLRAALLQNHGPVVSG
                     VSVRAAVDAAVEIEEVSALLLALGDRPARLLTEEEAGELARRYGSCWGE"
     gene            complement(7140..7643)
                     /locus_tag="FRZ02_RS22005"
                     /old_locus_tag="FRZ02_22005"
     CDS             complement(7140..7643)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008412579.1"
                     /locus_tag="FRZ02_RS22005"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22005"
                     /product="cupin domain-containing protein"
                     /protein_id="WP_008412579.1"
                     /transl_table=11
                     /translation="MTDPLTVPGEGFHPDFRDGSGHPAAPLHTRLHHIRAESLDTGTAQ
                     TEGMRRFAAVSGRTVGSEKLWMGQTHVAPATSSSDHHHGESETAIYVQSGHPEFVFVDG
                     HGDQAEEVRLRTSPGDYIFVPPYVPHREENPDPAEEAVVVIARSTQEAIVVNLPHLYAV
                     SEDD"
     gene            7787..8221
                     /locus_tag="FRZ02_RS22010"
                     /old_locus_tag="FRZ02_22010"
     CDS             7787..8221
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508305.1"
                     /locus_tag="FRZ02_RS22010"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22010"
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="WP_010639416.1"
                     /transl_table=11
                     /translation="MHISAKADYATRALLELAREPARPLTCESIASSQGIPFRFLKSVV
                     GELRKAGLVRSQRGCEGGYWLGRPADRITLLDVSRAIDGELLTLRGESVSGLAYPGAGA
                     GLPEVWRRVESAAAGILQGVTLTSLLADEAARTPAGRGAS"
     gene            8218..9150
                     /locus_tag="FRZ02_RS22015"
                     /old_locus_tag="FRZ02_22015"
     CDS             8218..9150
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946596.1"
                     /locus_tag="FRZ02_RS22015"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22015"
                     /product="DsbA family protein"
                     /protein_id="WP_146582377.1"
                     /transl_table=11
                     /translation="MRAAPARPALEVVEYTDPMCPWAWGSDPAFRRLRALLAGRASWRR
                     VYGLLFTDEDDAPPDPEAETAWYARHVAGISRHTGAPHARSLARVAACSWPSSLVAKAA
                     ELQGEGTAERVLRRLRESVFVLGEPADTLPLALSVVRGVPGLDPVRLASDAASDEVRER
                     VRADAAETRRPLPEAWAEPGASPHPGTAKETPDGGHRYALPTLLLRSGDARRLVPGWRE
                     LGEYTAAAEELCPGVLDAAPAPPSPAAALSRYGSLTDPERLLLGEGAWPPPGAVQVTTG
                     NGPVWLCPEEAPSHPAVARTVDGRAANRA"
     gene            9612..11180
                     /locus_tag="FRZ02_RS22020"
                     /old_locus_tag="FRZ02_22020"
     CDS             9612..11180
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008416120.1"
                     /locus_tag="FRZ02_RS22020"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22020"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_146582379.1"
                     /transl_table=11
                     /translation="MSGTAVPRPPVPRPHAAPRRPRAAVVAAALATAFSLTLSGCGGGS
                     SAASGAGSTLKWTSTYFPSHWDPVVAGSGAQFRELALVYASLTRTDEKGDAVPDLAESW
                     EYNDKGDEVTFRLRPGLKFSDGEPVDGAAVKAAVERAQKQKNSALFGDLTSIESVEADG
                     LNATVHLNQVDYQIPQLLGQRVLQIASPKAAASPAALDQKPVGAGPFVLRQLVPGTKAV
                     LEKNPDYWDAENIHIDDVELTSAPDASTVVSGLRTGVYNFADIAPSQAEAAKKAGLDVF
                     VQPGFNASNISLNINKAPFDDARVVDAVRHAVNRQEFVDKLTFGYGETTDQPFPKGYVA
                     YDPESENAYPYDPAKARKLLREAGHEPGDIKLDLVIPEEDPQAEIVQAQLAKVGITVGI
                     RIDKNWATPFFAKDLAFSLYSTTGRDSAVQTLTAHFGPDGPLNLSSPYEPKGFADAVAE
                     VRRTPLDAPGYPKVLREATRAGLKSQALVFTYSSPNLIAKSKSVSGLPANPAHIDWTGV
                     KIAGN"
     gene            11206..12231
                     /locus_tag="FRZ02_RS22025"
                     /old_locus_tag="FRZ02_22025"
     CDS             11206..12231
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008416118.1"
                     /locus_tag="FRZ02_RS22025"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22025"
                     /product="ABC transporter permease"
                     /protein_id="WP_146582381.1"
                     /transl_table=11
                     /translation="MTTTAPPAPGWHRGVTGTRAGRTVARVAAIVGRSVAVFVPVFLVA
                     TFVTFALRSLSGLSPARIQLGESATPQAVAQVEAEWGLDRPFLVQYGDWFAGVLRGDLG
                     TSWTNGADISTLIGLGLSVSLSIALFALLIGVVVGFALGTVAALRPATWLDRSVTGFVT
                     VISVMPAFVVGILLVTVFAVGLGLFPSAGYAPAEQGIGPWLAHITLPALALSLDVVADV
                     ARQLRSSLIAAYRENYVTGALVRGLSPRRVFFTHVLRNGIGPALATLGLKFPALVGASV
                     VTEWIFGLQGFGRFANDSAQTGDVPAVQGVLVVSIVLVVTFNLVVNLVLARVTPASQRG
                     V"
     misc_feature    11237..11252
                     /note="TFBS match to AfsQ1, Two-component system AfsQ1-Q2,
                     activator of antibiotic production, confidence: weak,
                     score: 16.86"
                     /tool="antismash"
     gene            12235..13125
                     /locus_tag="FRZ02_RS22030"
                     /old_locus_tag="FRZ02_22030"
     CDS             12235..13125
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946593.1"
                     /locus_tag="FRZ02_RS22030"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22030"
                     /product="ABC transporter permease"
                     /protein_id="WP_018470970.1"
                     /transl_table=11
                     /translation="MVRRVLALTSGRIAVAVLLVIALLALLGPLLAPQNPLAGSDNALA
                     TASGAHWLGTDYLGRDVLSRLLDGSRVSVLGSLEVAVTALVVGTLPGILSVYLGRTFEW
                     VTLRLTDTLVALPFLLFAVAVIALLGNGLTQAMLVTGVLVSPLFYRVSRAATLAVARAP
                     YVEAALISGASLGWTVRKHVWGKVLPPIAVALAQTVGTGFVIVSSLTFLGIGVQPPAPT
                     WGGLLASDLGYLDQRPWGPLAPALLIMITVWACNLLADAIRDVSGQAGRALDNDRKARA
                     HHLARTAPAPTGGAS"
     gene            13122..14021
                     /locus_tag="FRZ02_RS22035"
                     /old_locus_tag="FRZ02_22035"
     CDS             13122..14021
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946592.1"
                     /locus_tag="FRZ02_RS22035"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22035"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146582383.1"
                     /transl_table=11
                     /translation="MTAPSHRSTTGNTALAPVPAPAPGSAAAPPALLVRDLRISDLAQD
                     REIVHGVSFTLTPGRTVGIVGESGSGKTLTCRAALGILPDHFAVTGGSVEIDGTDAAGL
                     TTRRWTALRGSTISAVFQDPASYLNPSIPVGAQLAEVVRVKLGLRRRAARAQAVELLRA
                     VRLRDAEVVARQYPHELSGGMLQRVLIAAAVAAEPRVLIADEATTALDVTVQAEILDLL
                     ADLRERTGLALVVVSHDLAVVAQLCDEVLVMRQGEVVEQGPTRTVLHAPRHAYTRLLIS
                     EHESYGLEKFLTPKEAAR"
     gene            14018..14890
                     /locus_tag="FRZ02_RS22040"
                     /old_locus_tag="FRZ02_22040"
     CDS             14018..14890
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639406.1"
                     /locus_tag="FRZ02_RS22040"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22040"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146582385.1"
                     /transl_table=11
                     /translation="MSAEQPPAPSAEAGTAPRPVLEVTGLEVRYGRRRLPVLRGVSLDV
                     GPGETLGLIGETGSGKSTFARAVLGLVPAAAGSVVIDGEETRGHSRRQWRRLRRSGVVQ
                     YVFQDPLRSLDPDRTVAESLTEPLLVRGVTAAEAAERARAFLDQVRLSAELLDRLPGEL
                     SGGQRQRVAVARALVTEPRLVILDEPVSALDSANRVQILEILKDLRARGTALVLISHDL
                     GSVVGVADRTAVLYQGELVESGPSADVVNRPRHAYTRLLVSSAPTLHGARADRAGREAL
                     RAQLTDLSH"
     gene            14915..16255
                     /locus_tag="FRZ02_RS22045"
                     /old_locus_tag="FRZ02_22045"
     CDS             14915..16255
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1083: oxidoreductase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470967.1"
                     /locus_tag="FRZ02_RS22045"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22045"
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="WP_008416112.1"
                     /transl_table=11
                     /translation="MSRKLHLALHPYGVGGPGQHGLWKDPRVAKNASIDIDYYIHQAKA
                     AEHALFDALFIVDSQFINATYPAHYLNRLEPLTLLSAVATHTRHVGLVGTASSTYNSPF
                     NLARRFASLDHISGGRAGWNVVTSFDTGTSRNYGLDEHLDYATRYGRALEFVQVARGLW
                     DSYEDDAFPADVARGVFLDPDKLHALDHVGEHFRVAGPLNLSRSPQGQPVIFQAGVSEE
                     GRDLAARVAEGIYAPGGSLEQAQEYYADIKKRTAAYGRDPEHIKIFIHGGPVVAATDEK
                     ARRREREIFEEDNDLGRNLALLGRSFGAYDFSVHDLDAPFPNVAHLAEKGGRTAAAKII
                     DRAKAESLTLRQVAESVNAFRASPFVGAPDTVADAIERWFDAGTFDGINLAFRTTEELD
                     LFVDGVVPLLQRRGLFRTAYEADTLRGHLGLPIPANRHTEARLRTHG"
     gene            16352..17110
                     /locus_tag="FRZ02_RS22050"
                     /old_locus_tag="FRZ02_22050"
     CDS             16352..17110
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008416109.1"
                     /locus_tag="FRZ02_RS22050"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22050"
                     /product="alpha/beta hydrolase"
                     /protein_id="WP_146582387.1"
                     /transl_table=11
                     /translation="MSRYTDHPAPEGVTTRGTILVVPGRGETHETYARLGARLSADAYH
                     VRVVDPPRLDPADPAPSLTRFAKELGEAADAPDGVPAVRPVVVIGSDAGAAAVAAVLAR
                     TGASWQPDGVVLAGLPSRAAPERATWEEELDLRTACPVHRRRLTEDGQVRRGALGTPVP
                     APVLALAEESEIPVPTLLLAGDADPLVDHQALLAKARSLPRARLSRVRGAHHDVLNDAQ
                     HRSVAAEIVTFLEGLRDGMAPAVSVAASAW"
     gene            17160..>17396
                     /locus_tag="FRZ02_RS22055"
                     /old_locus_tag="FRZ02_22055"
                     /pseudo=""
     CDS             17160..>17396
                     /codon_start=1
                     /inference="COORDINATES: protein motif:HMM:NF015431.5"
                     /locus_tag="FRZ02_RS22055"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22055"
                     /product="LysR substrate-binding domain-containing protein"
                     /pseudo=""
                     /transl_table=11
                     /translation="MATAGARCSHEVLVGVFRRADVVPRYVHQLSQVHTILALVRAELG
                     LALVPRAAEALKLDGVVPRPVTGVEGEPVGLVAA"
     gene            complement(17422..18267)
                     /locus_tag="FRZ02_RS22060"
                     /old_locus_tag="FRZ02_22060"
     CDS             complement(17422..18267)
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639383.1"
                     /locus_tag="FRZ02_RS22060"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22060"
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="WP_010639383.1"
                     /transl_table=11
                     /translation="MDRAQLADFLRTRREALQPEDVGMPRGPRRRTRGLRREEAAALSG
                     MSTDYYSRLEQRRGPQPSEPMLAAIARGLRLSLAERDHLFRIAGHNTPSRPGDLRSDHI
                     TPGLMRILGRLDDTPAQVVSDVAETLAQTPMAAALLGDQTQFTGPERSLTYRWFTEPAA
                     RLLYPQEDHPLHSRYFTSGLRAAYSRQGAGGRAEELRDLLLDRSEEFASLWSAHEIDVP
                     RVDPKRLRHPELGVLTLQCQVLLDPEQNQTLLVYTAAPGSEDDEKLRLLPVLGTRPVGT
                     "
     gene            complement(18330..19085)
                     /locus_tag="FRZ02_RS22065"
                     /old_locus_tag="FRZ02_22065"
     CDS             complement(18330..19085)
                     /EC_number="1.1.1.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0070403 - NAD+ binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_KR (4-182). E-value: 2.8e-14. Score:
                     45.4. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS22065_PKS_KR.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001: short-chain dehydrogenase/reductase SDR"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470965.1"
                     /locus_tag="FRZ02_RS22065"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22065"
                     /product="SDR family NAD(P)-dependent oxidoreductase"
                     /protein_id="WP_146582389.1"
                     /sec_met_domain="adh_short (E-value: 7.5e-32, bitscore:
                     106.6, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTRIALITGANRGLGRSTALHLAEAGTDLILTYRSHAEEAETVVA
                     EARKLGRTAVALRLDTADTAAFPAFTEEVRAALAGRWDRDQLDILVNNAGHGVHAAFEE
                     TTEEQFDGLMDVHVKGVFFLTQALLPLIGNGGHILNVSTGLTRFIAAPTSAYAAAKGAV
                     EVLTRYLAKELGPRGIAVNALAPGATGTDFGGGGVRDDQETRGVLSGVTAMGRPGEPED
                     IGAAAAALLGEGTSWITGQRIEASGGMLL"
     aSDomain        complement(18540..19073)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS22065_PKS_KR.1"
                     /evalue="2.80E-14"
                     /label="FRZ02_RS22065_PKS_KR.1"
                     /locus_tag="FRZ02_RS22065"
                     /protein_end="182"
                     /protein_start="4"
                     /score="45.4"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="ALITGANRGLGRSTALHLAEAGTDLILTYRSHAEEAETVVAEARK
                     LGRTAVALRLDTADTAAFPAFTEEVRAALAGRWDRDQLDILVNNAGHGVHAAFEETTEE
                     QFDGLMDVHVKGVFFLTQALLPLIGNGGHILNVSTGLTRFIAAPTSAYAAAKGAVEVLT
                     RYLAKELGPRGIAVN"
     CDS_motif       complement(18990..19070)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS22065_0001"
                     /evalue="4.70E-07"
                     /label="PKSI-KR_m1"
                     /locus_tag="FRZ02_RS22065"
                     /protein_end="32"
                     /protein_start="5"
                     /score="22.5"
                     /tool="antismash"
                     /translation="LITGANRGLGRSTALHLAEAGTDLILT"
     gene            complement(19294..19812)
                     /locus_tag="FRZ02_RS22070"
                     /old_locus_tag="FRZ02_22070"
     CDS             complement(19294..19812)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007500840.1"
                     /locus_tag="FRZ02_RS22070"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22070"
                     /product="pyridoxamine 5'-phosphate oxidase family protein"
                     /protein_id="WP_146582391.1"
                     /transl_table=11
                     /translation="MRETPEELDTLQSLLDSSLSGSTAHLRSIVEGRTITATRLTGVLT
                     GMCTLALSTVTAKGEPRISGADGHFLHGRWHFGTARNAAKARHLAARPAASVAHMRGED
                     LGVFTHGTVEELNPENTEPTADWQELLAYLRDFYGDDTFDWNREVVYYRLNPHWMTVYA
                     PDLDKLTGT"
     gene            complement(20001..21098)
                     /locus_tag="FRZ02_RS22075"
                     /old_locus_tag="FRZ02_22075"
     CDS             complement(20001..21098)
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_C"
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024: chalcone and stilbene synthase domain protein"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639377.1"
                     /locus_tag="FRZ02_RS22075"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22075"
                     /product="type III polyketide synthase"
                     /protein_id="WP_003946584.1"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 1.3e-19,
                     bitscore: 66.3, seeds: 21, tool: rule-based-clusters)"
                     /sec_met_domain="Chal_sti_synt_C (E-value: 5.9e-20,
                     bitscore: 67.7, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAVLCRPAVAVPPHVITMEETLDLARSTHAGHDQLGLVLRLIRNT
                     GVATRHLVQPIGETLAHPGFEARNKVYEREAKARVPQVVHQALAEAELTAQDIDLIVYV
                     SCTGFMMPSMTAWMINSLGFRSDTRQLPIAQLGCAAGGAAVNRAHDFTRAYPGSNVLIV
                     ACEFCSLLYQPTDLGVGSLLSNGLFGDAVAAVVVRGEGGTGLSLERNGSHLVPDTEEWI
                     SYAVRETGFHFQLDKRVPGTMSMLAPALTALSAQHSWNVGELDFYIIHAGGPRILDDLC
                     THLELPSEMFAQSRATLTERGNIASCVVLDALDRYFASGKATEGARGMLAGFGPGITAE
                     ISLGTWATGEGRPAALTGAEARRPA"
     gene            complement(21186..22418)
                     /locus_tag="FRZ02_RS22080"
                     /old_locus_tag="FRZ02_22080"
     CDS             complement(21186..22418)
                     /GO_function="GO:0004497 - monooxygenase activity [Evidence
                     IEA]"
                     /GO_function="GO:0005506 - iron ion binding [Evidence IEA]"
                     /GO_function="GO:0016705 - oxidoreductase activity, acting
                     on paired donors, with incorporation or reduction of
                     molecular oxygen [Evidence IEA]"
                     /GO_function="GO:0020037 - heme binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) p450"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1007: cytochrome P450"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470963.1"
                     /locus_tag="FRZ02_RS22080"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22080"
                     /product="cytochrome P450"
                     /protein_id="WP_010639375.1"
                     /sec_met_domain="p450 (E-value: 3.4e-26, bitscore: 87.8,
                     seeds: 50, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTEAVPAAPDSAEVPTCPFDFAQGLDFDPALLAMLRSEERVARV
                     RMPYGEGDAWLVTRYEDVRTVTTDRRFSRNAVTGKDFPRMTPEPIVQTGAINLMDPPES
                     SRLRRLVRQSFAPRHLERMRGRTQSVVDGLLDAMAESGSPTDLFAHLALPLPLVTICEV
                     LDIPEADRHWLRAHAMTMMNMKPAGKEAAVRAKGELREYFARLTAERRRSPGADMISTL
                     ATAREGGEMLGEDELTVMAMVLLITGQDTTTYQLGNISYLLLTRDDVREQLRREPDSLP
                     RVLEELLRHIPFRKGVGIPRIATEDVELGGALIRAGDTVHVSYLTANRDGEKFERPDEI
                     DLDRPSVPHMTFGWGSHHCLGSPLAVMELEIALSTLLRRFPDLALAVEPGEVEWNATSI
                     WRYPLALPVTW"
     gene            22781..23464
                     /locus_tag="FRZ02_RS22085"
                     /old_locus_tag="FRZ02_22085"
     CDS             22781..23464
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894158.1"
                     /locus_tag="FRZ02_RS22085"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22085"
                     /product="ABC transporter permease"
                     /protein_id="WP_008416387.1"
                     /transl_table=11
                     /translation="MSPPAPDDCLARNTWICGEYLSTRRHILLDAVLEHLQLTAVPVAL
                     ALALAVPLAVVARRWSWAAGPVLAVTTILYTIPSLAMFSLLLPVYGLSASLVVAGLVLY
                     SLTLLVRNILAGLRAVPEETRQAARGMGYGPVRLLLTVELPLALPAAMAGLRIATVSAV
                     SLVTIGAIVGFGGLGNLIYAGMNTYFKAQVLTASVLCVVIAVAADLLLLGVQRLLTPWT
                     RAAGS"
     gene            23461..24132
                     /locus_tag="FRZ02_RS22090"
                     /old_locus_tag="FRZ02_22090"
     CDS             23461..24132
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1044: ABC
                     transporter, permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008416384.1"
                     /locus_tag="FRZ02_RS22090"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22090"
                     /product="ABC transporter permease"
                     /protein_id="WP_146582393.1"
                     /transl_table=11
                     /translation="MNTLTEAWRWLTDPAHWSGDGGITQRLTEHLVLTVVCLAVSCLIA
                     LPVALVLGHLGKGGALAVNLANIGRAVPTFAVLVLLLLTPVGRWSEGPTVVALVLFAVP
                     PLLTNAYVGMRGVDRDTVRAARGMGMTGRQVLTGVELPLALPMVMTGVRIAATQLVATA
                     TIAALAGGGGLGRIITAGFNLASTPQVVAGAVLVAALALAVEGAFVLAERLSPQRARGI
                     T"
     gene            24132..25076
                     /locus_tag="FRZ02_RS22095"
                     /old_locus_tag="FRZ02_22095"
     CDS             24132..25076
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639371.1"
                     /locus_tag="FRZ02_RS22095"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22095"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_146582395.1"
                     /transl_table=11
                     /translation="MRARALLAALLLTLLAACAGGPSLEDQGEITAPPGDSSRLTVGSA
                     GFTESDLLAQMYALLLRRAGYETELITVANRELYEPALESGRVDVVPEYAATFADWLNA
                     KENGPDAEPVGSPDLATTMKALRRLAAPRGLTVLDPGKAVDQNAFAVTREFAAEHSLRT
                     LSDLGASGLPVRLAAGDECVSRPYCRPGLEKTYGIDVTAVDPKGVGTTQAKRAVQSGQD
                     QMVLTTTTDATLDAFGLVLLEDDKKLQNADAVVPVVNRARAGSERVARALDALAPVLTT
                     ADLAGLNRQVDSWRRLPEDVARAYLEEKGLLGS"
     gene            complement(25080..26243)
                     /locus_tag="FRZ02_RS22100"
                     /old_locus_tag="FRZ02_22100"
     CDS             complement(25080..26243)
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_component="GO:0043190 - ATP-binding cassette (ABC)
                     transporter complex [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0015837 - amine transport [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003964372.1"
                     /locus_tag="FRZ02_RS22100"
                     /note="Members of the family are the ATP-binding subunit of
                     ABC transporters for substrates such as betaine, L-proline
                     or other amino acids, choline, carnitine, etc. The
                     substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly.; Members of the family are the ATP-binding
                     subunit of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22100"
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="WP_026048091.1"
                     /transl_table=11
                     /translation="MIRFEDVSKRYPDGTVAVDGLSFEVGRGELVTLVGPSGCGKTTTM
                     MMVNRLTEPTSGRVLVDGEDVMAVDPVQLRRRIGYVIQQVGLFPHRTVLDNTATVPTLA
                     GWRRGRARARAKELLELVGLDPAEFADRYPAQLSGGQRQRVGVARALAADPPVLLMDEP
                     FGAVDPVVRERLQNEFTAIQRALGTTVLLVTHDIEEAVRLGDRIAVYGRGRIEQYDTPA
                     AVLGHPADGYVAEFVGADRGLKRLSVTAIEPGDVEEPPVARTDEDARRAAARLREHAAR
                     WAVVLDPEGNLHGWVGLDELASAREGRPVRELARRMGAWVPVGVPLKQAFGVMLQHDAG
                     WVAVLDGDRFLGVLTPAKLHEALRRSVESDAKGVPRGEVDFDSVTDA"
     gene            26375..27688
                     /locus_tag="FRZ02_RS22105"
                     /old_locus_tag="FRZ02_22105"
     CDS             26375..27688
                     /NRPS_PKS="Domain: Abhydrolase_1 (52-208). E-value:
                     1.8e-17. Score: 55.7. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS22105_Abhydrolase_1.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF00561"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414864.1"
                     /locus_tag="FRZ02_RS22105"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22105"
                     /product="alpha/beta fold hydrolase"
                     /protein_id="WP_033238777.1"
                     /sec_met_domain="PF00561 (E-value: 2.4e-17, bitscore: 59.2,
                     seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDTRTATYRQPGVVLTDHRFSVPLDHDEPDGERIELYGREVVAA
                     EREGMPLPWLLYLQGGPGFGAHRLVGRPHWLGRALTEFRVLLLDQRGTGASTPASRQTL
                     PLRGGPEEQADYLTHFRADSIVRDCEAIRPGLTGGAPWTVLGQSFGGFCTTTYLSTAPE
                     GVATALFTGGLPSLDAHADDVYRAAYPRVTRKNEAHYARYPQDVERARRIAAHLLERPV
                     ELPGGYLLTAEAFQSLGILLGSGDGSHQLHFLLEDAFVRVPGGHALSDAFQEQVRAHLS
                     YAANPLYALLHEAIYAQDGRPTAWSAERVRGEFPRFDAARALAGDEPVLFTGETIHPWQ
                     FTADPALRPLRETAGLLAARTDWTPLYDPERLAANEVPAAAAVYHDDMYVDTADSLRTA
                     AAVRGLRPWVTNEFEHDGVRAGGPRVLDRLLALARDRA"
     aSDomain        26531..26998
                     /aSDomain="Abhydrolase_1"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS22105_Abhydrolase_1.1"
                     /evalue="1.80E-17"
                     /label="FRZ02_RS22105_Abhydrolase_1.1"
                     /locus_tag="FRZ02_RS22105"
                     /protein_end="208"
                     /protein_start="52"
                     /score="55.7"
                     /tool="antismash"
                     /translation="PWLLYLQGGPGFGAHRLVGRPHWLGRALTEFRVLLLDQRGTGAST
                     PASRQTLPLRGGPEEQADYLTHFRADSIVRDCEAIRPGLTGGAPWTVLGQSFGGFCTTT
                     YLSTAPEGVATALFTGGLPSLDAHADDVYRAAYPRVTRKNEAHYARYPQDVE"
     gene            27741..28472
                     /locus_tag="FRZ02_RS22110"
                     /old_locus_tag="FRZ02_22110"
     CDS             27741..28472
                     /EC_number="3.5.1.-"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PIG-L"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414866.1"
                     /locus_tag="FRZ02_RS22110"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22110"
                     /product="PIG-L deacetylase family protein"
                     /protein_id="WP_146582397.1"
                     /sec_met_domain="PIG-L (E-value: 2.2e-25, bitscore: 85.7,
                     seeds: 137, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQLAPMPEDWQRALAVVAHPDDLEYGCAAAVAQWTDSGREVAY
                     VLATRGEAGIDSLEPAISGPLREAEQRASAEVVGVGSVEFLGHRDGVIEYGPALRRDIA
                     AAIRRHRPELVITLNHRDTWGGTYRNTPDHVAVGRAALDAAADAGNRWIFPELGAEGLV
                     PWDGVRWVAVFGSDRPTHAVDAEPGLERGIRSLLAHRTYVEALTEEDPEQYCRNLLTEG
                     VRHSADRFGGRPAVTFELFPC"
     misc_feature    complement(27742..27756)
                     /note="TFBS match to VqsM, Regulator of quorum-sensing
                     signalling systems, confidence: medium, score: 17.8"
                     /tool="antismash"
     gene            28540..29175
                     /locus_tag="FRZ02_RS22115"
                     /old_locus_tag="FRZ02_22115"
     CDS             28540..29175
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription factor
                     activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="other (smcogs) SMCOG1148: hypothetical
                     protein"
                     /gene_kind="other"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639364.1"
                     /locus_tag="FRZ02_RS22115"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22115"
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="WP_008414868.1"
                     /transl_table=11
                     /translation="MSPRAHRPALPEPTPPPADTDTVLAGVGPRLRALRKERGATLAGL
                     SAATGISVSTLSRLESGNRRPSLELLLPIAAAHDVPLDRLVGAPPAGDPRVRLEPIEQG
                     NRTVIPLSRRPGGLQAFKWVLRPGEGCDPVEEQRTHEGYEWLYVISGRLRLLLGEHDFE
                     LGEGEAAEFDTRLPHWFGAIGDHPAEVLSLFGPQGERMHVRARPKSAR"
     gene            29301..30269
                     /locus_tag="FRZ02_RS22120"
                     /old_locus_tag="FRZ02_22120"
     CDS             29301..30269
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0003960 - NADPH:quinone reductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0048038 - quinone binding [Evidence IEA]"
                     /GO_function="GO:0070402 - NADPH binding [Evidence IEA]"
                     /NRPS_PKS="Domain: PKS_ER (18-315). E-value: 5.5e-52.
                     Score: 168.7. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS22120_PKS_ER.1"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ADH_zinc_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1028: crotonyl-CoA reductase / alcohol dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414870.1"
                     /locus_tag="FRZ02_RS22120"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22120"
                     /product="NADPH:quinone oxidoreductase family protein"
                     /protein_id="WP_129819095.1"
                     /sec_met_domain="ADH_zinc_N (E-value: 6.6e-30, bitscore:
                     99.6, seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQAWQVHRNGEPREVMSLADTARPEPGPGQVRLKVRAADVNFPDA
                     LLCRGQYQVRPPLPFTPGVEICGETEDGRRVLATTALPHGGFAEYALADEAALLPAPDA
                     LDDAEAAALHIGYQTGWFGLHRRAHLQAGETLLVHAAAGGVGSAAVQLGKAAGARVIGV
                     VGGADKARVAQELGCDLVIDRREDDLVAAVKEATGGKGADVVYDPVGGDAYTKSAKCVA
                     FEGRIIVVGFASGTIPAPALNHALVKNYSILGLHWGLYAVKDPASIGACHAALTELAAK
                     GAVKPLVSGRVPLAEAADAVQRVADGTTTGRLVVLPEGAAA"
     aSDomain        29355..30245
                     /ASF="ER domain putatively catalyzing 2S-configuration
                     product formation"
                     /aSDomain="PKS_ER"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS22120_PKS_ER.1"
                     /evalue="5.50E-52"
                     /label="FRZ02_RS22120_PKS_ER.1"
                     /locus_tag="FRZ02_RS22120"
                     /protein_end="315"
                     /protein_start="18"
                     /score="168.7"
                     /tool="antismash"
                     /translation="ADTARPEPGPGQVRLKVRAADVNFPDALLCRGQYQVRPPLPFTPG
                     VEICGETEDGRRVLATTALPHGGFAEYALADEAALLPAPDALDDAEAAALHIGYQTGWF
                     GLHRRAHLQAGETLLVHAAAGGVGSAAVQLGKAAGARVIGVVGGADKARVAQELGCDLV
                     IDRREDDLVAAVKEATGGKGADVVYDPVGGDAYTKSAKCVAFEGRIIVVGFASGTIPAP
                     ALNHALVKNYSILGLHWGLYAVKDPASIGACHAALTELAAKGAVKPLVSGRVPLAEAAD
                     AVQRVADGTTTGRLVV"
     CDS_motif       29697..29756
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_FRZ02_RS22120_0001"
                     /evalue="7.00E-08"
                     /label="PKSI-ER_m5"
                     /locus_tag="FRZ02_RS22120"
                     /protein_end="152"
                     /protein_start="132"
                     /score="24.9"
                     /tool="antismash"
                     /translation="GETLLVHAAAGGVGSAAVQL"
     gene            30266..31450
                     /locus_tag="FRZ02_RS22125"
                     /old_locus_tag="FRZ02_22125"
     CDS             30266..31450
                     /GO_function="GO:0016627 - oxidoreductase activity, acting
                     on the CH-CH group of donors [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_M"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010988535.1"
                     /locus_tag="FRZ02_RS22125"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22125"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_146582399.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3.7e-12, bitscore:
                     42.7, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_M (E-value: 1.1e-21, bitscore:
                     72.6, seeds: 43, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 4.5e-19, bitscore:
                     64.9, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDADDLRARTRALLADRPPATTSRADFLAARFDAGLAWVHYPEG
                     LGGLGAARSLQSVVDAELAAAGAPDNDPRRIGIGLGMAAPTILAYGTEEQKRRFLRPLW
                     LGEEVWCQLFSEPGAGSDLAALSTRAVLGDDGVWTVTGQKVWTSSAHLARWAILIARTD
                     PAQPKHRGITYFLCDMTDPGVEVRPLRQITGEAEFNEVFLTDVRIPDSHRLGEVGDGWQ
                     VARTTLMNERVSIGGSTGGRESGMIAPLARTWRERPERRTHALHQRLVTLWVEAEVARL
                     TGERLRQQLAVGQPGPEGSGLKLSFARLNQQISGLEVELLGDEGLLYDDWTMRRPELVD
                     FTGRGPGYRYLRSKGNSIEGGTSEVLLNIVAERVLGLPTEPRTDKDVAWKDLAR"
     gene            31447..32568
                     /locus_tag="FRZ02_RS22130"
                     /old_locus_tag="FRZ02_22130"
     CDS             31447..32568
                     /EC_number="1.-.-.-"
                     /GO_function="GO:0016491 - oxidoreductase activity
                     [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acyl-CoA_dh_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1006: acyl-CoA dehydrogenase"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639358.1"
                     /locus_tag="FRZ02_RS22130"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22130"
                     /product="acyl-CoA dehydrogenase family protein"
                     /protein_id="WP_146582401.1"
                     /sec_met_domain="Acyl-CoA_dh_N (E-value: 3e-14, bitscore:
                     49.5, seeds: 790, tool: rule-based-clusters)"
                     /sec_met_domain="Acyl-CoA_dh_1 (E-value: 8.5e-26, bitscore:
                     86.8, seeds: 49, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSATPSLLATETEDDLRAAVRSLLTTHSAADRVLARAESGAPYDR
                     ELWKTLTGSMGLAGLLVPEADGGQGAGHREAAVVVEELGRAVAPVPYLTGAVVTPATLL
                     ALPERTAEVSALLAEVAAGSAVAILAVPLTTAPGDPLPEVTTDGGGLHGTVRSVADAAG
                     ADVLLVAADSGLYAVPAGAPGVTVTPLTALDLTRPLAAVQLDGARGTLLAPAADAAPAV
                     RAGLLSGAGLLASEQLGLAEWCLTETVRHLKDRHQFNRPLGSFQALKHRLAQLWLDVAG
                     IRPAATAAADLLATGEGGPAEAQLAVAVAQVYASPVAVRAAEEALQLHGGIGMTWEHPV
                     HLYLKRAKGDSVAFGGAGRHGQEVARLAELPAP"
     misc_feature    complement(32662..32680)
                     /note="TFBS match to FuR_variant_2, Ferric Uptake
                     Regulator, confidence: weak, score: 23.35"
                     /tool="antismash"
     misc_feature    32663..32679
                     /note="TFBS match to NuR, Nickel-responsive regulator,
                     confidence: weak, score: 21.72"
                     /tool="antismash"
     gene            32726..34333
                     /locus_tag="FRZ02_RS22135"
                     /old_locus_tag="FRZ02_22135"
     CDS             32726..34333
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1068:
                     extracellular solute-binding protein family 5"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639356.1"
                     /locus_tag="FRZ02_RS22135"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22135"
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="WP_030771277.1"
                     /transl_table=11
                     /translation="MTSRTDRRPVRLAGTLAATAALTVAATSCSAPGGGTDAKGSATGT
                     AVVGIAYEPDSLSPLLGYGKDGNSKIFDGLLTHDEKLDLRPALATELPEISEDGRTYTF
                     QLREGVTFTDGKPFTARDVVFTYETILDPKTNNASRTELDAVESVEAKGDHTVVFHLKY
                     PYAPFAERTVLPIAPAHIAGEQDVNTGDFTTKPIGTGPYELVSWSKGEKLTFKANPDYW
                     GGAPKIKNFTMAIIKDDDVRATRLRSGDLDGAILPPNLAKAFKDGDTATYAAKSFDYRV
                     VTLPTGNKVTGDTDIRRALDLAVDREAMVDSILDGAGKPAYGPVPTDSPWFTEGTERAH
                     DLKAAADLLDEAGWKKGKDGVRAKDGVRAAFPLWYLSGDKLRQDHALAYASDAKKLGVE
                     VKVQAGTWEVIQPRMPKDAVLAGGGSPADPDFDQYTLLKSSLAGDGFNNMAHYDNPAVD
                     KALEKGRRSGEHAERQAAYDTVQRELVKNPGYTFLTHIDHVYVVDKRFGTLTTQVEPHD
                     HGLASGPWWNVEDWKPAK"
     gene            34366..35331
                     /locus_tag="FRZ02_RS22140"
                     /old_locus_tag="FRZ02_22140"
     CDS             34366..35331
                     /GO_process="GO:0055085 - transmembrane transport [Evidence
                     IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1118:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019891160.1"
                     /locus_tag="FRZ02_RS22140"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22140"
                     /product="ABC transporter permease"
                     /protein_id="WP_146582403.1"
                     /transl_table=11
                     /translation="MARMTGRRLLFAVPVLLAVTFAVFAVADASPFDPVKAYAGAAGLT
                     ASQENLDQLRANLGVDQPLAVRWWEWITGALTGDLGHSAVMRQPVADVIAERIGWSVLL
                     AALAFVVAVLAGTTLGVLAARRRGSLVDRAVTSLAYTLEAAPTFWLGLLAVWLFALQLG
                     WLPAGGLTDTGSTTVTAGQLTTHVILPAAVLAASQLPWFALYVRQGVGDALDEDPVRGA
                     RARGLAEHTVLLGHALRSGLLPVLTLIGSRVPELITGALLVETVFSWPGIAAATVQAAT
                     AVDFPLLAATTVLATAAVLLGNLVADLLYGLADPRVGFDG"
     gene            35324..36193
                     /locus_tag="FRZ02_RS22145"
                     /old_locus_tag="FRZ02_22145"
     CDS             35324..36193
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1085:
                     binding-protein-dependent transport systems"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003946570.1"
                     /locus_tag="FRZ02_RS22145"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22145"
                     /product="ABC transporter permease"
                     /protein_id="WP_003946570.1"
                     /transl_table=11
                     /translation="MADLALPTAPGRVARTARTWKLRISATLVAGFVLAVLLVPPLVGL
                     DEQAVDLGAKLLPPSLDHPFGTDDVGRDLLLRCVYGLRVSLLVGVVAALVATVLGTAVG
                     AAAGALGGWTDRLVMRCVDAFSSVPHLLLGIFIVALFRPGVWPVVVSVGLTHWVSTARI
                     VRAEILSLRARPYIDAAVSGGASRLRLARRHLIPGVLPQAGLAAVLMIPHAIWHESALS
                     FLGLGLPTHQASLGTLVQSARGTLLAGDWWPTLFPGLFIIVPTLAIAGLAGAWRERLNP
                     RRRSELML"
     gene            36190..37191
                     /locus_tag="FRZ02_RS22150"
                     /old_locus_tag="FRZ02_22150"
     CDS             36190..37191
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639352.1"
                     /locus_tag="FRZ02_RS22150"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22150"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146582405.1"
                     /transl_table=11
                     /translation="MTVLSVRGLTVRFRMRESAPVRAVTDVSFDLAAGECLALVGESGC
                     GKSVLASALLGLLPGNAETAGSALLAGVGDDPATDLIAADEATLARTVRGRRVGLVPQS
                     PAAHLTPVRTVRAHLTETVRRLTGTRGRDALRTATEAAAARVSFPAGHLDRHPHELSGG
                     LAQRAATALALVGDAPLLLADEPTTGLDRDLVERTVDELRRHTGATRALLMITHDLAAA
                     ARIADRVAVMYAGRLVEIADADAFFGTPGPRHPYARGLLDALPERAFRPVPGRPPELAA
                     LPAGCAFAARCAHADTACATQPPLTGGLACHHPHTAPADLVHPPQAAEAPGA"
     gene            37184..37897
                     /locus_tag="FRZ02_RS22155"
                     /old_locus_tag="FRZ02_22155"
     CDS             37184..37897
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470951.1"
                     /locus_tag="FRZ02_RS22155"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22155"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146582407.1"
                     /transl_table=11
                     /translation="MLELLSLTAGYDRRAPVVRDVTLTLAPGEAVGLLGPSGCGKSTLA
                     RVAALLHRPDSGRVVIDGETARGYRHRAPRAQRTAFGVVFQQPRQSADPRLRLADLIAE
                     PLRATGRPEGAADKAAETADTVGLGGDLLGRRPHEVSDGQLQRACLARALILRPRYLVC
                     DEMTAMLDASTTAALVGVVEEYRRETGAALLAVGHDRVLLDRWCDRTVEWSELGSRHDG
                     LATAKPPAERSPSVR"
     misc_feature    complement(38017..38032)
                     /note="TFBS match to FuR_variant_1, Ferric Uptake
                     Regulator, confidence: weak, score: 15.81"
                     /tool="antismash"
     gene            38018..38212
                     /locus_tag="FRZ02_RS22160"
                     /old_locus_tag="FRZ02_22160"
     CDS             38018..38212
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008414879.1"
                     /locus_tag="FRZ02_RS22160"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22160"
                     /product="hypothetical protein"
                     /protein_id="WP_008414879.1"
                     /transl_table=11
                     /translation="MAITVSVALLLLILAVIFIRSGGLKTSHAIICVLLGFLLAGTSAA
                     PTIHHTLVSTANMINGVGR"
     gene            complement(38193..39149)
                     /locus_tag="FRZ02_RS22165"
                     /old_locus_tag="FRZ02_22165"
     CDS             complement(38193..39149)
                     /codon_start=1
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) APH"
                     /gene_kind="biosynthetic-additional"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894166.1"
                     /locus_tag="FRZ02_RS22165"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22165"
                     /product="aminoglycoside phosphotransferase family protein"
                     /protein_id="WP_146582409.1"
                     /sec_met_domain="APH (E-value: 1.3e-07, bitscore: 27.6,
                     seeds: 156, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MITLPPQFVRTTVAREGDTGAAWLAGLPATVAELLERWECVPEGE
                     VLHGGVGLVVPVRRAAGGAPGVIKVSFPHPGNVHEPDAFTVWGGHGAVLLHERDDARYA
                     MLLERAGASSLAEVADGDEVAEVAGLLSHRLAVPAPPGLPLLRDRAAGWEARLLKDAAE
                     VPHALPGHTLDAALATVREAARYRPATMVHGDLHPRNILRAGREPWLAVDPKGLAGDPA
                     YDGGTLLKTRTPVLLSSADPLKDAHRTLAVFAEAAGLDRDRVTRWAQLLLVEALFWGRR
                     HGFRRARGGPERDRLAGFAQWLAERLVARTGSTCPPR"
     gene            complement(39219..39695)
                     /locus_tag="FRZ02_RS22170"
                     /old_locus_tag="FRZ02_22170"
     CDS             complement(39219..39695)
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894167.1"
                     /locus_tag="FRZ02_RS22170"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22170"
                     /product="DinB family protein"
                     /protein_id="WP_146582549.1"
                     /transl_table=11
                     /translation="MTGSVAGGERQVLETFLDYQRGVVRRKAAGLTEEQARRRHVPSST
                     TMAGLLKHLALVEDNWFVRVLGQQPSVLPDPEVSFAVDEEETVAGLIAAYEAACARSRE
                     SAAGYPLDHVVPHAWLGQVSLRWILTHMIEETARHAGHADILRELTDGTTGTVG"
     gene            complement(39773..40168)
                     /locus_tag="FRZ02_RS22175"
                     /old_locus_tag="FRZ02_22175"
     CDS             complement(39773..40168)
                     /NRPS_PKS="Domain: Polyketide_cyc2 (1-126). E-value:
                     1.3e-14. Score: 46.7. Matches aSDomain:
                     nrpspksdomains_FRZ02_RS22175_Polyketide_cyc2.1"
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639343.1"
                     /locus_tag="FRZ02_RS22175"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_22175"
                     /product="SRPBCC family protein"
                     /protein_id="WP_146582410.1"
                     /transl_table=11
                     /translation="MATRTVSRAGPVAPETAWERYARPALWSQWAPHIRRVETDAGRIA
                     PGVRGRVFSYAGVRVRFTVERVDEEQRRWTWRVGLGPLVLRLGHEVTAAPGGGSRTRLT
                     VSGPLPVVVLYRPVAAWALKRLVAPAP"
     aSDomain        complement(39791..40165)
                     /aSDomain="Polyketide_cyc"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_FRZ02_RS22175_Polyketide_cyc2.1"
                     /domain_subtypes="Polyketide_cyc2"
                     /evalue="1.30E-14"
                     /label="FRZ02_RS22175_Polyketide_cyc2.1"
                     /locus_tag="FRZ02_RS22175"
                     /protein_end="126"
                     /protein_start="1"
                     /score="46.7"
                     /tool="antismash"
                     /translation="ATRTVSRAGPVAPETAWERYARPALWSQWAPHIRRVETDAGRIAP
                     GVRGRVFSYAGVRVRFTVERVDEEQRRWTWRVGLGPLVLRLGHEVTAAPGGGSRTRLTV
                     SGPLPVVVLYRPVAAWALKRL"
     misc_feature    complement(41083..41097)
                     /note="TFBS match to OsdR, Development and stress
                     management regulator, confidence: medium, score: 27.18"
                     /tool="antismash"
ORIGIN
        1 tggggcaccg acccgaccgc ttacctcgac gaggcggccc tcgcgctggt ccgccgccac
       61 cgcgtccggc tggtgtcgtt catgcccgag acccagcgcg cgtgggccga ggagcggtac
      121 gcgagcgccc ccgcgcccgt caccgtcgtg ggcgacgcca ccggcgccct caaggactgg
      181 ttcgacgtcc gcgcctgcgg cctggtcctg ctgcgccccg accacttcgt ggccgccgcc
      241 tgcctcaccc ggcaggcccc ccgggccctc gccgccctgc gcgaggcggc ctccctcacc
      301 accgggcccg ccgcggaaca ggccccgcac tccctggaag gagcctcggc atgaccctcg
      361 ccctggtcac catgtcgcac agtccgctgc tcgagtacgc cgacccgccc gccgaggtga
      421 aggacgccgt ccagggcgcc ttctccgccg cccgcacctt cgtcagggcc tacgacccca
      481 ccctggtcgt ctccttcgcc cccgaccact acaacggctt cttccacgac ctgatgccac
      541 cgttctgcat cggctacgcg gccgtgggcg tcggcgacta cggcaccacg gcgggcccgc
      601 tgaacgtgcc ggccgggcgc gccgcggaac tcgcccagtg ggtggccgag cgcgacctcg
      661 acgtggccgt ctcccgccgc atggaggtcg accacggcgc cgtccagccg ctggagatcc
      721 tcttcgacgg catcgacacg gtgccggtcg tcccggtctt cgtcaacggc gtcgccacgc
      781 ccttcgtctc catgcgccgg gtgcgcgagc tcggcgaggc gatcggcggc tacctcgcgg
      841 ggctggaggg cgagcgggtc ctcgtcatcg gctccggcgg cctctcccac gacccgcccg
      901 tgccccagtg ggccaccgcc gacgacacgg cccgggcgat gctcctcgac ggccgccacc
      961 ccacggccgc cgcacgcgac gcacgccagc aacgggtcat cgacaccgca agggcgttcg
     1021 ccgccggcac ggcccccatc caggacctca accccgactg ggaccgcgcc ctgatggcga
     1081 ctttcgcctc cggcgacctc acccccgccg acgcgatgac cccggaccgg atggccgagg
     1141 acgcgggcaa ctccgcccac gaggttcgca cctggctcgc cgccttcgcc gccctcggcg
     1201 cggcgggccc ctacgaggtg acccactcct tctaccgccc gatcaaggag tacatcgcgg
     1261 ggttcggggt gatgacggcg cgttcggtcg cggggtaggc gggcggcccg aacggcgggc
     1321 ccggggcgtg tcaggcgggg ccggccaggt ggagttcggg gccggagtcc cggacgccct
     1381 cggcggcggc ctcggtgagg gcggagtcgg tgatgatggc gtcgaagtcg gccagggggg
     1441 cgacgcggta cttgccgaag gtgccgaact tggaggagcc ggcgaccagg acggcgctgc
     1501 gggagctgtc cagggcggcg cgcttcacct cgaccttggc gtcggagggg gtggtgacgc
     1561 cgcgcagcag gtcccaggag ctggtgctga tgaaggccat gtccagggcg aggtggcgca
     1621 gggtcgctgc ggcgagccgg ccgacggtgg agcggttggc cgcctcgacc tggccgccga
     1681 cgtggatgat ctccaggtgg ggggcctcgg tcatcaggcg gtccaccgtg ctgaagtcgt
     1741 tgctgaccac cgtgagccgc tcgtggtgga cgaggtgcgg gaccgcggcg agcagggtgg
     1801 tgcccgcgtc caggtagagc gtcatgccgt cctccacgag ggaggcggcc cggctcgcca
     1861 tggcctcctt ctgcggctgc tccacctggg tcttcgcctg gtggctgggc tcgctgcgga
     1921 cctggctggc gatgcgcacg ccgccgggga cggtgaagac caggccctgg cgctccagtt
     1981 cggcgatgtc gcggcggacg gtcatgtgcg agacgccgaa gagctgcgtg atctgctgca
     2041 cgctcaggac gccgtcgcgg cgcaggtgct tgagcagctt ctcccgccgc tggtcgggga
     2101 tgagcggagg cgcgtcttcg gtcatggtcg tatcttccct cctgccacgg gggcggctcg
     2161 caccgcccgt cggttgtgcc gggctcccgc cggggtgccg gaccccggcg ggagcaccgg
     2221 tcagcccccg acgaacaggc tgaggagcag cacgccgccg aggctcagca gggactggag
     2281 cgagagcatc aacgtccagg tgcggaaggt ctgcggcacg gagagctgga agtactcctt
     2341 gaagagccag aagcccgagt cgttgacgtg cgagagcatg accgcgccgg acgccgtggc
     2401 cagcaccagc agttcggggg agagcccggg gtacgcgccg accaggggcg cgacgatgcc
     2461 ggtggcggcg gcggtggcca ccgtggccga gccgaggcag atccgcagca gcgcggcgac
     2521 cagccaggcg aggaccagag gcgggatcgc ccagtccacg gcgtagtcgg agatgatctt
     2581 gtcgatgccg gtggcggtca gcatcgcctt gaggccgccg cccgcgccga ggatgaggac
     2641 gatgccgccg accgggccga gccccttggc ggccatcttc tggatctggc cgaggccgaa
     2701 gccggagcgc acgcccaggg cgaagaaggc gaagagcacg gcgaccagca gggacagcac
     2761 gggggagtcg cacgcctcga agacggtgta cggcgcggtg ccctcgcggg tggcggaggt
     2821 gccgatcgtg ccgatcagca tgaggaccgg cggcagcagg acggtgatca gggccagggt
     2881 gaacgaggcc gggcggcgct ggttctcggg cgcgggaccg gcgtcgggga ccgggccctt
     2941 gtcgaggtcg ggcgcgggcc cgaaccagcg gctggcgtac cgggtgagca ccgggccggt
     3001 gaggaccgcg atcgggatgc cgatgatcag gccgtagagg atggtcaggc cggtgctcgc
     3061 gtcgtaggcg gagacggcga gggtggggga ggggtgcggg ggcagcaggc cgtgcgagat
     3121 gtacaggccg gcggccatcg gcaggccgac gtagagcaga tgggtgccgg tgcgcttggc
     3181 gaccgcgtag accagcggga ccagcatcac gaagctgacg tcgaacaggt gcggcatgcc
     3241 gatgagcagg gccgcggccg tgatcgccgt gggaatccac ttcaccgggc gggcgccgat
     3301 gaagaccgtg gcgatccggt cggcgccgcc ggagcccagc aggatgccgc cgagcagggt
     3361 gccgaggccg atggtggggc cgacgctctt gagggcgtcg ccgaagccgt cctggaagtg
     3421 cgtgacggtg tcgcccgggc ctatcccgga ggcgaggccg aggccgatcg cggagagggc
     3481 gagcgccagg aaggggtgga gcttggcctt ggtgatcagc aggatcagga cgacgacggc
     3541 cgcgaggccg aggagcaggt gctggatgtc ggtgctcatg agccgttcac cggtccggtg
     3601 gcggggcggg cggcgcgccc ggcggtccag gcgtcgagga gggcggcgtc ggcgtcggcg
     3661 aggtggccga cggtgatcag ctcgcccgcc gcgacgtcgg cggcgagggt ggcgtgggcg
     3721 gcgaggtaca ggggggccgt gccggcgggg gtgtcctcgt cgcggaggag gaccgcctgg
     3781 acgccggtga cgtcgtggtg gtggccgccc atcgtcagca cggtgccggc gggcaggtcg
     3841 cgctcggcgc ggccggccag cacggcgtgc ccgcgcgggt cggtgccgcc ggagggccgc
     3901 tggtccagga cggcggagag caggctgacg ggcgtctcga cacccatcag gtggtacggc
     3961 aggtagacgg cggcgtactt gccgtcgcgg ctgacgacgt ggcccttgcc gcgcagggtc
     4021 tcccaggtga cggggtcgcc ggtgcggacg acgacgaaga cgccgccggc gaaggacgcc
     4081 tcgccgggca gccgcagggc gctgaagacg tcgacggcgc cggggcggcg cagcacaccg
     4141 ccgtcctcgc gcagggcgta gacgtcggcg agttcggcga tgcgggcgac cgggtagtgg
     4201 agccgctcgg tgtcggggcg gaagccggtg ctggtggcga cgacggccat ctcgcagtag
     4261 tcggcggtgg cgccggtggg gagcgcggcg acggcggcgg cgcgggcggc cagggtggag
     4321 cggacgtcgt cgccgaggtc gagcaggccg gcgagttccg gcgcggggac ggtggtgtcg
     4381 agctgcgtca cggtgccggc ggcggggtcc aggacgaggt cgtactcggt ggacttgccg
     4441 atggcgacga tctccagccc gagcgtctcg gcccagctga ccaggccgat gaggttggcg
     4501 ggctggtcac cgtcggcggt ggtgtagacg ctgccgtggg tgcgggccag ttcggcgagg
     4561 tggagcccgg cgaccgagtc gacctccttg ctgaccatgg ccacgtggcg gccgccggtc
     4621 agggcctggc gggccatctc gtaaccggcg gcggggctgc cggtggcctc cacgaggatg
     4681 tcccagtcgc ccgcgatcag caggtcgccg tcggcgacca gggcgaggtg accgtcctgc
     4741 ccggcgtcgc ggaccgcccg ggcgtcgccg cagatccgga gctgcgaggc gtcgtacccc
     4801 agctcgacca gcatcgcgcg cagtcccgcc acgtcctggt cgcagaggac ggcgggacga
     4861 aggcgcggga tgcgcagggt ctgtgcgagg agggtccggg cgaatccgcc accggcgccg
     4921 gagagtgcgt accgcacggt ccggtcgccg cccggggcga acaggtgaag gaagttcatg
     4981 ggcactcctc agtgggtgcg cgtggcgatg gtgcgcgagg cgggcgcggg gtccgcgaag
     5041 cgaggggacg gctcccggcg gccgtggggc ggctcagccc gggagcgggt taacaatatg
     5101 tatcaaggta actcagggac gtaaagtctg ttaacatttt ttcacacatc aactcattga
     5161 gcggcccacg cgggtcaccc gccacggccg cgccacacaa tggaggtccc atgccgaccc
     5221 tcggggccat cgccgacgac ttcaccggcg ccacggacct ggccaccatg ctggtgtcgc
     5281 ggggcttccg gacgctggtg gccatcggcg ccgacgccgt ggacccggag gcgtccgccg
     5341 aggccgacgc ggtcgtcgtc gccctcaagt cgcgcaccgc gccggtggag gaggcggtcg
     5401 ccgactcgct ggccgcactg cgcgccctgc gcgccgcggg atgccgccgg tactacttca
     5461 aatactgctc caccttcgac tccacgcccc ggggcaacat cggcccggtc gccgacgccc
     5521 tgctggaagc ggtccacgcc gaccgcaccg tggtcgtgcc cgccttcccc gccaccggcc
     5581 gcaccgtccg cgacggactc ctgtacgtgc acggcgagcc gctcgaccgg agcccgatgc
     5641 gccaccaccc gctcaccccg atgacggacg cctcgctcgc gcgcctcctc cgcccgcaga
     5701 cccgccaccc ggtccggcag atccccctgg ccaccgtccg cgcgggcgcg gcggagctgc
     5761 gcgccgccgt cgacgccccc gaggcgagcg gggcgctcct cgtcgtggac gccgagaccg
     5821 acgacgatct gcgcaccgtc tccgccgcca ccgcgcacct cggcctggtc accggcgccg
     5881 ccggcctcgc cctcggcctg accggccccc gccccggcgc cgcccgcgcc acccccgcct
     5941 cctcgcccgg cgacccggcc gccgtgctgt cgggcagcgc ctcctccacc acccgggccc
     6001 aggtggccca cggccgcgcc cacctgccgc accgcaagct ggacgtcgcc gccctgcgcc
     6061 gcgacctccc cgccaccgtg gccggtctgg ccgccttcgc ccgcgagcag tggcggctgg
     6121 acccggcgcg ccctccgctc ttctacgccg tcgacgacct cgccgacctg gagcgcacca
     6181 ccccgccggg cgaggcgccc gcctccgccc tgatcgagga ggccctcgcc gccctcgccg
     6241 tcgccctcgt cgacgacggc gcccgccgcc tgctggtggc cgggggcgag acctccggcg
     6301 cggtggtcac cgcactggag gtgcgcggcc tcgccatcgg cgcgcccctc gcgccgggcg
     6361 tcacctgggc ccgcgccgag accgggaccg gcggcggccg caacatcgac ctcgccctga
     6421 agtccggcaa cttcggcggc accgacatct tcaccgaagc atggagcgcc ctcgtatgag
     6481 cgacgtgcga gccggcctcg cggccgccgg agcacacctc gccgccctcg gcctgagccc
     6541 cggcagctcc gggaacctca gcgtccgcga cggcggcctg ctgtacatca ccccgaccgg
     6601 ggcggacctc tcccgcctcg acccggacgg cctgagcgtc ctggaccggg acggcaccca
     6661 cctcgaaggc ccccggccgt ccaaggagtt cccgctccac accgccctgt accggcgcga
     6721 cgccgcgacc cgggccgtcg tccacctgca ctcccggcac gccgcggcgc tctcctgcct
     6781 gccgccgtgg tccgggcgga gcgccgtccc gccgctcacc ccgtacttcg tgatgcgggt
     6841 cggccagacg cccctcctgc cctacgcgcc gcccggcgac cccggccagg ccaaggagct
     6901 ggaacggctg ccgttcccgc tgcgggccgc cctgctccag aaccacggcc cggtcgtctc
     6961 cggtgtctcg gtccgggcgg cggtggacgc agccgtcgag atagaggagg tctccgccct
     7021 cctgctcgcg ctcggcgacc ggccggcccg cctgctgacg gaggaggagg cgggcgagct
     7081 ggcccggcgg tacgggtcct gctgggggga gtgaggcccc ggccgggccc gccggcgggt
     7141 cagtcgtcct cggaaacggc gtacaggtgg ggcaggttga ccacgatcgc ctcctgggtg
     7201 ctgcgggcga tcaccaccac cgcctcctcg gcggggtcgg ggttctcctc gcggtgcggc
     7261 acgtacggcg gcacgaagat gtagtcgccg ggggaggtgc gcaggcgcac ctcctcggcc
     7321 tggtcgccgt ggccgtccac gaagacgaac tccgggtggc cgctctgcac gtagatggcg
     7381 gtctcggact ccccgtggtg gtggtcggag gaggaggtgg cgggggcgac gtgggtctgg
     7441 cccatccaga gcttctcgga gccgaccgtc ctgccgctga ccgccgcgaa ccggcgcatc
     7501 ccctcggtct gcgcggtgcc ggtgtccagg gactcggccc ggatgtggtg cagtcgggtg
     7561 tggagcgggg ccgccgggtg gccggagccg tcgcggaagt ccgggtggaa gccttcgccg
     7621 ggcacggtca aggggtctgt catggcgggc acgctacgac tcgcgggaaa agacgtcaac
     7681 aggtgtcctt tgccgttcac ctgcggcaac accgccgcaa cgaacggccc ggctcctcct
     7741 tgcggtccct cgcccgccgc cgggcgtctc cggcatcatg agcgtcatgc atatctcggc
     7801 gaaagctgac tacgccacgc gcgccctgct ggaactcgcc cgcgagcccg cccgtccgct
     7861 cacctgcgag tcgatcgcct cctcgcaggg aatcccgttc cggttcctga aatccgtggt
     7921 gggggagttg cgcaaggccg ggctggtgcg cagccagcgc ggctgcgagg gcgggtactg
     7981 gctggggcgg ccggccgacc ggatcacgct gctggacgtc tcccgcgcga tcgacggcga
     8041 actgctcacc ctgcgcggcg aatccgtgag cggactcgcc tatccggggg ccggggcggg
     8101 cctgcccgag gtctggcgcc gtgtggagtc cgcggccgcc ggcatcctcc agggggtcac
     8161 gctgacctcg ctgctcgcgg acgaggcggc gcggacgccg gccgggcggg gggcctcgtg
     8221 agggcggccc cggcccggcc ggccctggag gtcgtcgagt acaccgaccc gatgtgcccc
     8281 tgggcctggg gctccgaccc cgccttccgg cggctgcgcg cgctgctggc gggccgggcg
     8341 agctggcgcc gggtctacgg tctgctcttc accgacgagg acgacgcgcc cccggacccg
     8401 gaggcggaga cggcctggta cgcgcgccac gtcgccggga tcagccggca caccggggcg
     8461 ccccacgccc ggtcgctggc gcgggtggcg gcctgctcgt ggccctcctc gctggtggcc
     8521 aaggcggccg aactccaggg ggaggggacg gcggagcggg tgctgcggcg cctgcgggag
     8581 tccgtcttcg tcctgggcga gcccgcggac accctgccgc tggccctgtc cgtggtccgg
     8641 ggcgtgcccg ggctggaccc ggtgcgactg gcctcggacg cggcctcgga cgaggtgcgg
     8701 gagcgggtgc gggccgacgc cgccgagacc cggcgcccgc tgcccgaggc gtgggcggaa
     8761 cccggcgcct ccccgcatcc gggaaccgcc aaggagaccc cggacggcgg ccaccggtac
     8821 gccctgccga ccctgctgct gcgctccggc gacgcccgcc gactggtgcc gggctggcgg
     8881 gagttggggg agtacaccgc ggcggccgag gagctgtgcc ccggtgtgct cgacgccgcg
     8941 cccgcaccgc cgtcgccggc cgccgcgctg agccggtacg ggagcctcac cgaccccgag
     9001 cgtctgctcc tgggggaggg cgcctggccc ccgccggggg cggtccaagt gacgacgggg
     9061 aacgggccgg tgtggctgtg ccccgaggag gcccccagtc atccagccgt cgcccgcacg
     9121 gtcgacggcc gtgctgcgaa ccgcgcttga ccagcggcgg agtgccgtcc caccgaatga
     9181 gacaccaaaa ggtgtcgatt gacttcgggt gccaccggcg acaagatgct cccatgctca
     9241 cgacgcaccc cggcgtggtg tgccgctacg tggacctgcg gcgcacctcc agcgccctct
     9301 gtcgctgacc gacagcacct tccggccgga cggccgccaa cgcccgcccc tcgggcggcc
     9361 cgccgtcccg ccgcgcccgc cgagcaggcc cgccgatccc gagcggcccc ccctccccgg
     9421 cacccccctt tccccgccct ccttccggac ggccccgacg gacgcgccgc cgcgcgtgcc
     9481 gccggggtgg tacgccaccg cgaaccgcac ccgcggtcgc gcacggctcc gtccggacgg
     9541 ggcgtgagcc acctctcccg gcccgcccgg acccgccgtc gcgcgctccg ccatgccgaa
     9601 gaaggaacga gatgtctgga acagccgtcc cccgtcctcc cgtgccccgc ccccacgcgg
     9661 ccccgcgccg cccgcgcgcc gccgtcgtgg cggccgctct cgccaccgcc ttctccctca
     9721 ccctcagcgg ctgcggaggc gggtcgtccg ccgcctcggg cgccggctcc acgctcaagt
     9781 ggacctcgac ctacttcccc tcgcactggg acccggtggt ggccgggagc ggcgcccagt
     9841 tccgcgaact cgccctggtg tacgcgtcgt tgacgcgcac cgacgagaag ggggacgccg
     9901 tccccgacct cgccgagagc tgggagtaca acgacaaggg cgacgaggtc accttccgcc
     9961 tgcgccccgg actgaagttc agcgacggcg agccggtcga cggcgccgcc gtcaaggccg
    10021 ccgtcgaacg cgcccagaag cagaagaact cggcgctctt cggcgacctg acctccatcg
    10081 agtcggtcga ggcggacggg ctgaacgcca ccgtccacct caaccaggtc gactaccaga
    10141 tcccccagct gctcggccag cgcgtcctcc agatagccag ccccaaggcc gccgcctcgc
    10201 ccgcggccct cgaccagaag ccggtcggcg cgggcccctt cgtcctcagg caactcgtcc
    10261 cgggcaccaa ggcggtgctg gagaagaacc cggactactg ggacgccgag aacatccaca
    10321 tcgacgacgt cgagctgacc tccgcaccgg acgcctccac cgtcgtctcc ggcctgcgga
    10381 ccggcgtcta caacttcgcc gacatcgccc ccagccaagc cgaggccgcc aagaaggccg
    10441 gcctcgacgt cttcgtccag cccggcttca acgcctccaa catcagcctc aacatcaaca
    10501 aggcgccgtt cgacgacgcc cgggtcgtcg acgccgtacg gcatgccgtc aaccgccagg
    10561 aattcgtcga caaactgacc ttcggctacg gggagaccac cgaccagccc ttccccaagg
    10621 gatacgtggc ctacgacccc gagtcggaga acgcctaccc ctacgacccg gccaaggcca
    10681 ggaagctgct gcgcgaggcg ggacacgagc ccggcgacat caagctcgac ctggtcatcc
    10741 cggaggagga cccgcaggca gagatcgtgc aggcccagct cgccaaggtc gggatcaccg
    10801 tcggcatcag gatcgacaag aactgggcca ccccgttctt cgccaaggac ctggccttct
    10861 ccctctactc gaccacgggc cgcgactccg ccgtgcagac cctcaccgcc cacttcggtc
    10921 cggacggccc gctcaacctc agctcgccct acgagcccaa gggattcgcc gacgccgtcg
    10981 ccgaggtccg ccggacaccg ctggacgcac ccggctaccc gaaggtgctg cgcgaggcga
    11041 cccgtgccgg gctgaagagc caggccctgg tcttcacgta ctcctcgccc aacctgatcg
    11101 ccaagagcaa gtcggtgtcc ggactgcccg ccaatccggc gcacatcgac tggaccggcg
    11161 tgaagatcgc cgggaactga agcccgcgga gaggagggac ttcccatgac gacgaccgcg
    11221 ccccccgccc ccgggtggca ccgcggagtc accgggacca gggccgggcg gacggtggcc
    11281 cgtgtggcgg ccatcgtcgg ccgctccgtc gcggtcttcg tgcccgtctt cctggtcgcg
    11341 accttcgtga ccttcgcgct gcgctccctg agcgggctca gcccggcccg catccagctg
    11401 ggcgagagcg ccacaccgca ggccgtcgcg caggtcgagg ccgagtgggg cctcgaccgg
    11461 cccttcctcg tccagtacgg ggactggttc gccggggtgc tccgcggcga cctcggcacc
    11521 agctggacca acggcgccga catctccacc ctcatcggcc tcggcctctc ggtgagcctg
    11581 tcgatcgctc tgttcgccct gctcatcggc gtggtggtgg gcttcgccct cggcaccgtg
    11641 gccgccctgc gcccggccac ctggctcgac cggtccgtca ccggcttcgt caccgtgatc
    11701 tcggtgatgc ccgccttcgt cgtcggcatc ctcctggtca ccgtcttcgc cgtcgggctc
    11761 ggcctcttcc cctcggccgg gtacgccccc gccgaacagg gcatcggccc ctggctcgcc
    11821 cacatcaccc tcccggcgct cgccctcagc ctcgacgtcg tcgccgacgt cgcccgccag
    11881 ctgcgttcca gcctgatcgc cgcctaccgg gagaactacg tgacgggcgc cctcgtacgg
    11941 ggcctcagcc cccgccgggt cttcttcacc cacgtcctgc gcaacggcat cggcccggcc
    12001 ctcgccacgc tggggctgaa gttccccgca ctggtcggcg cctccgtcgt gaccgagtgg
    12061 atcttcggac tccagggctt cggccggttc gccaacgact ccgcgcagac cggcgacgta
    12121 ccggcggtgc agggcgtcct cgtggtgtcg atcgtcctgg tcgtcacctt caacctcgtc
    12181 gtcaacctgg tgctggcccg ggtgacaccg gcctcccagc gaggagtgtg aaccatggtg
    12241 cgccgcgtcc tcgccctcac ctccggccgt atcgccgtcg ccgtcctcct ggtgatcgcg
    12301 ctgctcgccc tgctgggccc gctgctcgcc ccgcagaacc cgctggccgg cagcgacaac
    12361 gccctggcca ccgcctccgg cgcgcactgg ctgggcaccg actacctcgg ccgggacgtg
    12421 ctgagccggc tgctcgacgg ttcccgcgtc agcgtgctcg gctcgctcga agtcgccgtc
    12481 accgcgctgg tggtcggcac cctgccgggc atcctctccg tctacctggg ccggaccttc
    12541 gagtgggtca ccctccggct caccgacacc ctggtggccc tgcccttcct cctcttcgcc
    12601 gtcgccgtga tcgccctgct cggcaacggc ctcacccagg ccatgctggt caccggggtc
    12661 ctggtctccc cgctcttcta ccgggtctcc cgggccgcga cactcgcggt ggcccgcgca
    12721 ccgtacgtgg aggcggcgct catctccggc gcctccctcg gctggaccgt acgcaagcac
    12781 gtgtggggca aggtgctccc gccgatcgcc gtcgcgctcg cccagaccgt cggcaccggc
    12841 ttcgtcatcg tctccagcct caccttcctc ggcatcggcg tgcagccacc cgctcccacc
    12901 tggggtgggc tgctcgcctc cgacctcggc tacctcgacc agcgcccgtg gggccccctc
    12961 gcgcccgcgc tgctcatcat gatcaccgtc tgggcctgca acctgctcgc cgacgccatc
    13021 cgtgatgtat ccggccaggc gggccgggcg ctggacaacg accgcaaggc gcgcgcccac
    13081 cacctcgcca ggaccgcacc cgctcccacc ggaggtgcct catgaccgcc ccgtcccacc
    13141 ggagcaccac ggggaacacg gccctcgcgc cggtccccgc gcccgcaccc gggtccgccg
    13201 ccgcaccccc tgccctcctc gtacgcgacc tgcgcatcag cgacctggcc caggaccggg
    13261 agatcgtcca cggcgtgagc ttcacgctca ccccgggccg gaccgtcggc atcgtcggcg
    13321 agtccggcag cggcaagacc ctcacctgcc gtgccgcgct gggcatcctc cccgaccact
    13381 tcgcggtgac cgggggcagc gtcgagatcg acggcaccga cgccgccggg ctgaccacgc
    13441 gccggtggac ggccctgcgc ggctccacca tcagcgccgt cttccaggac cccgcctcgt
    13501 acctcaaccc gtcgatcccg gtcggcgccc aactcgccga agtggtccgc gtcaagctcg
    13561 gactgcggcg gcgggccgcc cgcgcgcaag cggtcgaact gctgcgggcg gtacggctgc
    13621 gggacgccga agtggtcgcc cgccagtacc cgcacgaact ctccggcggc atgctgcaac
    13681 gcgtcctcat cgccgcggcc gtcgccgccg agccccgcgt cctgatcgcc gacgaggcca
    13741 ccaccgccct cgacgtcacc gtgcaggccg agatcctcga tctcctcgcc gacctgcgcg
    13801 agcgcaccgg tctggccctc gtcgtcgtct cccacgacct ggcggtcgtc gcccagctct
    13861 gcgacgaggt gctcgtcatg cggcagggcg aggtcgtcga gcagggcccg acccgcaccg
    13921 tcctccacgc cccgcgccac gcctacacac ggctgctgat cagcgagcac gagagctacg
    13981 gactggagaa gttcctcacc ccgaaggagg cggcacggtg agcgccgaac agcccccggc
    14041 cccgtcggcg gaagccggga ccgccccgcg cccggtcctg gaggtgaccg gcctggaggt
    14101 gcgctacggg cgccgccgcc tcccggtcct gcggggcgtc tccctcgacg tcggccccgg
    14161 cgagaccctc ggcctgatcg gcgagaccgg ctcgggcaag tccaccttcg cccgcgccgt
    14221 cctcggcctc gtcccggccg ccgccgggtc ggtcgtcatc gacggcgagg agacccgcgg
    14281 ccacagccgg cggcagtggc gccgcctgcg ccgcagcggc gtcgtccagt acgtcttcca
    14341 ggacccgctg cgcagcctcg acccggaccg caccgtcgcg gagtccctga ccgaacccct
    14401 gctcgtccgg ggcgtcaccg ccgccgaggc cgccgaacgg gcccgggcct tcctcgacca
    14461 ggtccgcctg tccgccgaac tgctcgaccg gctgcccggc gaactctccg gcggccagcg
    14521 ccagcgggtc gccgtcgccc gggccctggt caccgagccg cgcctggtca tcctcgacga
    14581 gccggtcagc gccctggact ccgccaaccg cgtacagatc ctggagatcc tcaaggacct
    14641 gcgggcccgc ggcaccgccc tcgtcctcat ctcgcacgac ctcggctcgg tcgtcggtgt
    14701 cgccgaccgc acggccgtgc tgtaccaggg cgagctggtc gagtcaggcc cctccgcgga
    14761 cgtggtcaac cggccccgtc acgcctacac ccgcctcctc gtcagctcgg cgcccaccct
    14821 gcacggcgcc cgcgcggacc gcgccggacg cgaggcgctg cgcgcccagt tgaccgacct
    14881 ctcccactga accccggaca gacaggaccc cgccatgtcc cgcaagctcc acctcgccct
    14941 gcacccctac ggcgtcggcg gccccggcca gcacggactt tggaaggacc cgcgcgtcgc
    15001 gaagaacgcc agcatcgaca tcgactacta catccaccag gccaaggcgg ccgaacacgc
    15061 cctcttcgac gcgctgttca tcgtcgacag ccagttcatc aacgccacct acccggccca
    15121 ctacctcaac cgcctggaac ccctcaccct gctctcggcg gtcgccaccc acacccgcca
    15181 cgtcggtctg gtcggcaccg ccagctcgac ctacaactcg cccttcaacc tcgcccgccg
    15241 cttcgcctcg ctcgaccaca tcagcggcgg ccgcgccggc tggaacgtcg tcaccagctt
    15301 cgacaccggc acctcccgca actacggcct ggacgaacac ctcgactacg ccacccgcta
    15361 cggccgggcc ctggagttcg tccaggtggc ccgcgggctc tgggactcct acgaggacga
    15421 cgccttcccc gccgacgtgg cgcgcggcgt cttcctcgac ccggacaagc tgcacgccct
    15481 cgaccacgtc ggtgagcact tccgggtcgc cggcccgctc aacctctccc gctcgcccca
    15541 ggggcagccc gtcatcttcc aggccggggt ctccgaggag ggccgcgacc tcgccgcccg
    15601 cgtcgccgag ggcatctacg ccccgggcgg ctcactggag caggcccagg agtactacgc
    15661 cgacatcaag aagcgcaccg ccgcctacgg ccgcgacccc gagcacatca agatcttcat
    15721 ccacggcggg ccggtcgtcg ccgccaccga cgagaaggca cggcggcggg aacgcgagat
    15781 cttcgaggag gacaacgacc tcggccgcaa cctcgccctg ctcggccgct cgttcggcgc
    15841 gtacgacttc agcgtccacg acctcgacgc gcccttcccc aacgtcgcgc acctggcgga
    15901 gaagggcggc cggaccgccg ccgccaagat catcgaccgg gcgaaggccg agagcctgac
    15961 cctgcgacag gtcgccgagt cggtcaacgc gttccgcgcg tcccccttcg tcggagcgcc
    16021 ggacaccgtc gccgacgcga tcgagcggtg gttcgacgcc ggcaccttcg acggcatcaa
    16081 cctcgccttc cgcaccaccg aggaactcga cctcttcgtc gacggagtcg ttcccctcct
    16141 ccagcgccgc ggcctgttcc gcaccgccta cgaggcggac accctgcgcg gccacctcgg
    16201 cctgccgata cccgccaacc gccacaccga ggcccgtctc cggacgcacg gctgacctcg
    16261 ccgacccctc gcgtcccgcc gggggccggg gcggtgggct ccggcccccg accgagccct
    16321 gccgggccac ctgaccacct gcggagactt gatgagccga tacaccgacc accccgcacc
    16381 cgagggcgtg accacccggg ggacgatcct cgtcgttccc ggacgcggag agacccacga
    16441 gacctacgcc cggctcgggg cgcggctctc cgccgacgcc taccacgtcc gcgtcgtcga
    16501 cccgccgcgt ctcgatccgg cggacccggc accgtccctc acccgtttcg ccaaggagct
    16561 gggggaggcc gccgacgccc cggacggagt cccggcggtc cggcccgtgg tggtgatcgg
    16621 ctccgacgcc ggcgccgccg cggtggccgc cgtcctcgcc cgcaccggag cctcctggca
    16681 gccggacggc gtcgtcctcg cggggctccc ctcgcgtgcc gccccggagc gggcgacctg
    16741 ggaggaggag ctggacctgc gcaccgcctg cccggtgcac cgccgccgcc tcaccgagga
    16801 cggccaggtc cgccggggcg ccctggggac cccggtgccg gccccggtgc tcgccctggc
    16861 cgaggagagc gagatcccgg tccccaccct gctcctggcc ggcgacgccg acccgctcgt
    16921 ggaccaccag gccctgctgg ccaaggcccg ctcgctgccc cgcgcccgcc tctcgcgcgt
    16981 gcgcggcgcc caccacgacg tgctgaacga cgcccagcac cggtccgtcg ccgccgagat
    17041 cgtcaccttc ctcgaagggc tccgggacgg catggccccg gccgtctcgg tcgcggccag
    17101 cgcctggtga cccggcccgg ccgagccgcg catctcccgc ctcccgccga aaggccgtca
    17161 tggccaccgc cggggcccgc tgctcccacg aggtgctggt cggggtcttc cgccgggcgg
    17221 acgtcgtccc gcgctacgtg caccagctca gccaggtgca cacgatcctc gcgctggtcc
    17281 gcgccgagct ggggctcgcc ctggtaccca gggcggcgga ggcgctcaag ctggacggcg
    17341 tcgtgccgcg cccggtgacg ggggtcgaag gagagccggt cggactcgtc gcggcctggc
    17401 ggggagccgc ggcaggaccg gtcaggtgcc cacggggcgt gttcccagta ccggcagcag
    17461 ccgcagcttc tcgtcgtcct ccgaccccgg ggcggccgtg tacaccagga gtgtctggtt
    17521 ctgttcgggg tccagcagca cctggcactg gagggtgagc acgcccagtt ccggatggcg
    17581 caagcgcttc gggtcgacgc gggggacgtc gatctcgtgg gcgctccaca gcgaggcgaa
    17641 ctcctcgctg cggtccagga ggaggtcgcg cagttcctcg gcgcgaccgc ccgctccctg
    17701 ccgggagtag gcggcgcgca ggcccgaggt gaagtagcgg ctgtgcagcg ggtggtcctc
    17761 ctgcggatac agcagccggg cggcgggctc ggtgaaccac cggtaggtga ggctgcgttc
    17821 ggggccggtg aactgtgtct ggtcaccgag gagcgccgcg gccatggggg tctgggcgag
    17881 ggtctccgcc acgtcgctga cgacctgcgc gggggtgtcg tccagtcggc cgaggatgcg
    17941 catcaggccg ggcgtgatgt ggtccgagcg cagatcgccg gggcgcgagg gggtgttgtg
    18001 cccggcgatg cggaagaggt ggtcgcgttc ggcgagcgag aggcgcaggc cccgtgcgat
    18061 ggccgcgagc atcggttccg acggctgcgg cccgcgccgc tgctccagcc ggctgtagta
    18121 gtcggtggac atgccgctca gcgccgccgc ctcctccctg cgtaggccac gggtccggcg
    18181 ccgcggcccg cggggcatcc ccacgtcctc cggttgcagg gcctcccggc gggtgcgcag
    18241 gaagtcggcg agttgcgctc ggtccacggt tccggtctcc ctcgtgcccc gtacgcgagg
    18301 tcggggcgtc ggcgatgtgc gagtagggct cagagcagca tgccgcccga cgcctcgatg
    18361 cgctgcccgg tgatccagga ggtgccctcg ccgagcagtg cggcggccgc ggcgccgatg
    18421 tcctcgggct caccggggcg gcccatggcg gtgacgccgc tcagcacgcc gcgtgtctcc
    18481 tggtcgtcac ggacaccacc gccgccgaag tcggtgccgg tggcacccgg tgcgagcgcg
    18541 ttgaccgcga tgccgcgcgg ccccagttcc ttcgcgaggt agcgggtgag gacctccacg
    18601 gcgcccttgg ccgccgcgta cgcggaggtg ggcgcggcga tgaagcgggt caggccggtg
    18661 gagacgttga ggatgtgtcc gccgttcccg atcagcggca gcagcgcctg cgtgaggaag
    18721 aagaccccct tgacgtggac atccatcagc ccgtcgaact gctcctcggt ggtctcctcg
    18781 aacgcggcgt gcaccccgtg cccggcgttg ttgacgagga tgtcgagttg gtcgcggtcc
    18841 caccgcccgg cgagtgccgc ccggacctcc tcggtgaagg cggggaacgc ggcggtgtcc
    18901 gcggtgtcca gccgcagggc gaccgccgtg cggcccagct tccgggcctc ggccaccacg
    18961 gtctccgcct cctcggcgtg cgaacggtag gtgaggatca gatcggtgcc ggcttcggcg
    19021 aggtgcaggg cggtgctgcg gcccaggccg cggttggcac cggtgatcag ggcgatgcgc
    19081 gtcatggtgg ttccttccgg caaggtgcgg gcggaccacc ggtccgccgc cttccccgca
    19141 acggtgtcgc aggccggggg gccgatgaag gcagcagtga tccagggatc gccggtcccc
    19201 ctgtacggcg tacctgtccg gagggcggcc acgtccaggt ccgccccgca cccgtgtacg
    19261 cgcgggtgcg ggccctcgtc gacgggtccg gtgtcacgtg ccggtgagct tgtcgaggtc
    19321 gggggcgtag acggtcatcc agtgcgggtt cagccggtag tagacgacct cgcggttcca
    19381 gtcgaaggtg tcgtcgccgt agaagtccct taggtaggca aggagttcct gccagtcggc
    19441 cgtgggctcg gtgttctcgg ggttcagctc ctccaccgtg ccgtgggtga acacgccgag
    19501 gtcctcgccg cgcatgtgcg cgacgctggc ggccggacgg gcggcgagat ggcgggcctt
    19561 ggcggcgttg cgcgccgtgc cgaagtgcca ccggccgtgc aggaagtgcc cgtcggcgcc
    19621 gctgatccgc ggttcgccct tcgcggtcac cgtggagagg gcgagcgtgc acatgccggt
    19681 gaggaccccg gtgagccgcg tcgccgtgat ggtgcggccc tcgacgatcg agcggaggtg
    19741 tgcggtcgag ccggagaggg aggagtccag gagggactgg agcgtgtcga gttcttctgg
    19801 ggtttcgcgc atacgtccat ggtcggccgt aaacccgaca ccttctgtcg ccattgttga
    19861 aacagcgccg aggttgctcc gcgcgggttg cgtccggtgc tgcgtggagg gcagcagatg
    19921 gggggagggg gcacggcctc gcgttccagg tggctcaggg cgccaacctg accgcgggcc
    19981 gtgccccccc ctgcccgggc tcaggccggg cggcgtgcct cggcgccggt cagggcggcc
    20041 gggcgtccct caccggtggc ccaggtgccc agggagatct cggcggtgat gcccggcccg
    20101 aagccggcga gcatgccccg ggcgccctcg gtggccttgc ccgaggcgaa gtaacggtcg
    20161 agggcgtcca ggacgacgca gctggcgatg ttgccccgtt cggtgagggt cgccctgctc
    20221 tgcgcgaaca tctcggacgg cagctccagg tgggtgcaga gatcgtcgag gatgcggggg
    20281 ccgcccgcgt ggatgatgta gaagtccagc tcgccgacgt tccacgagtg ctgcgcggag
    20341 agcgcggtca gggcgggcgc cagcatcgac atggtgccgg gcacccgctt gtcgagctgg
    20401 aagtggaaac ccgtctcccg caccgcgtac gagatccact cctcggtgtc ggggaccagg
    20461 tgggagccgt tgcgctccag gctgagcccg gtgcccccct cgccccgcac cacgacggcg
    20521 gccaccgcgt caccgaacag cccgttggac aggagcgagc cgacacccag gtcggtgggc
    20581 tggtagagca gggagcagaa ctcgcaggcc acgatcagga cgttgctgcc cggataggct
    20641 ctggtgaagt cgtgcgcccg gttgacggcc gcgccgcccg ccgcgcagcc cagctgggcg
    20701 atggggagct ggcgggtgtc ggagcggaag cccagcgagt tgatcatcca ggccgtcatc
    20761 gagggcatca tgaagccggt gcacgagacg tagacgatca ggtcgatgtc ctgcgcggtc
    20821 agctccgcct cggcgagcgc ctggtggacg acctgcggga cgcgggcctt ggcctcgcgc
    20881 tcgtagacct tgttgcgggc ctcgaagccc gggtgggcga gggtctcgcc gatgggctgg
    20941 accaggtgcc gggtggcgac accggtgttg cggatcagcc gcagcaccag gccgagctgg
    21001 tcgtggcccg cgtgggtgct gcgggccaga tcgagggtct cctccatggt gatgacgtgc
    21061 ggcgggacgg caacggcggg acggcagaga acggccatgg gattctcgtc atctcttcag
    21121 ggcgcgcgaa cgcgtcttgg ggggcgcgaa ggcgcggggc cgcgcgagcg cgagggggaa
    21181 gggcgtcacc aggtgacggg cagggcgagc gggtagcgcc agatggaggt ggcgttccac
    21241 tcgacctcgc cgggctccac ggcgagcgcc aggtcgggga agcgccgcag cagcgtggag
    21301 agggcgatct ccagctccat caccgccagc ggcgagccga ggcagtggtg cgagccccag
    21361 ccgaaggtca tgtgcgggac ggagggccgg tccaggtcga tctcgtcggg ccgctcgaac
    21421 ttctcaccgt cacggttggc ggtcaggtac gagacgtgca cggtgtcccc ggcacggatc
    21481 agggcgccgc ccagctccac gtcctcggtg gcgatccgcg ggatgcccac gcccttgcgg
    21541 aacgggatgt ggcgcagcag ctcctccaag acgcgcggca gcgagtcggg ctcgcgacgc
    21601 agctgctcgc ggacgtcgtc gcgggtcagc aggaggtagg agatgttgcc gagctggtag
    21661 gtggtggtgt cctggccggt gatgagcagc accatcgcca tcacggtcag ctcgtcctcg
    21721 ccgagcatct cgccgccctc gcgggcggtg gccagggtgc tgatcatgtc ggcgccgggg
    21781 gagcggcgcc gctcggcggt gagccgcgcg aagtactccc ggagctcgcc cttggcgcgg
    21841 accgcggcct ccttcccggc cggcttcatg ttcatcatgg tcatcgcgtg tgcccgcagc
    21901 cagtgccggt cggcctcggg gatgtccagc acctcgcaga tcgtcaccag cggcaacggc
    21961 agcgccaggt gggcgaagag gtcggtgggc gaaccgctct ccgccatggc gtccagcagt
    22021 ccgtccacca ccgactgggt gcggccgcgc atccgctcca ggtggcgcgg ggcgaacgac
    22081 tgccgcacca gccgccgcag cctgctgctc tccggcgggt ccatcaggtt gatggcaccc
    22141 gtctgcacga tcggctccgg ggtcatccgg gggaagtcct tgccggtgac ggcgttgcgg
    22201 ctgaacctgc ggtcggtggt gacggtacgt acgtcctcgt accgcgtcac cagccaggcg
    22261 tcaccctcgc cgtacggcat ccggacccgg gccacccgct cctcgctccg caacatcgcc
    22321 agcagcgccg ggtcgaagtc gagcccctgg gcgaagtcga acgggcaggt gggtacctcg
    22381 gcggagtcgg gtgcggcggg tacggcttca gtgctcacgg cggcgggccc ttctgtcggt
    22441 cctggatgtg ctcacgcgga tcaggcgtgt ccttctcgac gccgcaccgg ggacgggagg
    22501 ggtatgccac gccgcgccgg tggcgatacc tgaggtccca cggacagccg aacgacgcca
    22561 tccggtcacg ccctggtgta cccctgccgc gccgggaaaa ccggaggtcg ggcccctctc
    22621 cctcccccgg gcgagcgcac cccggcacat cgcgcgccgc ccagtgcgcc cccggcggac
    22681 gcgggctccc ggcggcctcg cacgcacgcc cgggcggggc ctgcacccgc ccgggccaac
    22741 ccggggagcc acccgccgcc gcgggcgttc caatggaccg atgagcccgc ccgcgccgga
    22801 cgactgcctg gcccgcaaca cctggatctg cggcgagtac ctgagcaccc gccgccacat
    22861 cctcctcgac gcggtgctcg aacacctcca gctcaccgcc gtgcccgtcg ccctcgcgct
    22921 ggccctcgcc gtgccgctgg ccgtcgtcgc ccgccgctgg agctgggcgg ccggccccgt
    22981 cctcgccgtg acgacgatcc tctacacgat cccctcgctg gcgatgttct cgctgctcct
    23041 cccggtctac ggcctctccg cctcgctggt cgtcgccggg ctcgtcctgt actcgctgac
    23101 gctgctggtc cgcaacatcc tcgccgggct gcgcgccgtg cccgaggaga cccggcaggc
    23161 ggcgcgcggc atggggtacg ggccggtgcg gctgctgctc accgtcgagt tgccgctggc
    23221 actcccggcc gccatggcgg ggctgcggat cgccaccgtc tccgccgtct ccctcgtcac
    23281 gatcggcgcc atcgtcggct tcggcggcct cggcaacctc atctacgccg ggatgaacac
    23341 ctacttcaag gcgcaggtcc tcaccgcctc cgtgctctgc gtggtcatcg ccgtcgccgc
    23401 cgacctgctc ctcctcggcg tgcagcggct cctcaccccc tggaccaggg cggccggctc
    23461 gtgaacaccc tcaccgaggc ctggcgctgg ctcaccgacc ccgcccactg gtcgggcgac
    23521 ggcggcatca cccagcggct caccgaacac ctcgtcctca ccgtggtctg cctcgccgtc
    23581 agctgcctga tcgcgctgcc cgtcgccctg gtcctcggcc acctcgggaa gggcggtgcc
    23641 ctcgccgtca acctcgccaa catcggccgc gccgtcccca ccttcgccgt cctcgtcctc
    23701 ctcctgctca ccccggtcgg ccgctggagc gagggcccca ccgtcgtcgc cctcgtcctc
    23761 ttcgccgtcc cgccgctgct caccaacgcc tacgtcggga tgcgcggcgt cgaccgcgac
    23821 accgtccgcg ccgccagggg catggggatg accggacgcc aggtgctgac cggcgtggaa
    23881 ctgcccctcg ccctgcccat ggtcatgacc ggcgtccgga tcgccgccac ccagctcgtc
    23941 gccaccgcca ccatcgccgc gctcgccgga ggcggcggcc tcggccggat catcaccgcc
    24001 gggttcaacc tcgccagcac cccgcaggtg gtcgccggag ccgtcctcgt cgccgccctc
    24061 gccctcgccg tggaaggcgc cttcgtcctc gccgaacggc tctccccgca gcgtgcccgg
    24121 gggatcacct gatgcgcgcc cgcgccctcc tcgccgccct cctgctgacc ctcctggccg
    24181 cctgcgccgg cggacccagc ctggaggacc agggcgagat caccgccccg cccggcgaca
    24241 gctcccgcct gaccgtcggc tccgccggct tcaccgagtc cgacctgctc gcccagatgt
    24301 acgcgctgct gctgcgccgc gccggctacg agacggagct gatcaccgtc gccaaccgcg
    24361 agctgtacga accggcgctg gagagcggcc gcgtcgacgt cgtccccgag tacgccgcca
    24421 ccttcgccga ctggctcaac gccaaggaga acgggcccga cgccgaaccc gtcggctcgc
    24481 ccgacctggc caccaccatg aaggcgctgc gccgcctcgc cgccccgcgc ggcctcaccg
    24541 tcctcgaccc cggcaaggcc gtcgaccaga acgccttcgc cgtcacccgg gagttcgccg
    24601 ccgagcactc cctgcgcacc ctcagcgacc tcggcgcctc cggcctcccg gtccgcctag
    24661 cggcgggcga cgagtgcgtc tcccggccgt actgccggcc ggggctggag aagacgtacg
    24721 gcatcgacgt caccgccgtc gaccccaagg gcgtcggcac cacgcaggcc aagcgggcgg
    24781 tgcagagcgg gcaggaccag atggtgctca ccaccacgac cgacgccacc ctcgacgcct
    24841 tcggcctggt cctgctggag gacgacaaga agctccagaa cgccgacgcg gtcgtccccg
    24901 tcgtcaaccg cgcccgcgcc gggagcgagc gggtcgcccg cgccctggac gccctcgccc
    24961 cggtcctcac caccgccgac ctcgccggcc tcaaccggca ggtcgacagc tggcggcggc
    25021 tgcccgagga cgtggcccgc gcctacctgg aggagaaggg gctgctcggc tcctgagcct
    25081 caggcgtccg tcaccgagtc gaagtccacc tcgccgcggg gcacgccctt cgcgtccgac
    25141 tccaccgagc ggcgcagcgc ctcgtggagc ttggccgggg tcagcacgcc caggaagcgg
    25201 tccccgtcca gcaccgccac ccacccggcg tcgtgctgga gcatcacccc gaacgcctgc
    25261 ttcagcggca cccccaccgg cacccacgcc cccatccgcc gggccagctc ccgcaccggc
    25321 cgcccctcgc gcgccgaggc cagctcgtcc agccccaccc agccgtgcag gttcccctcc
    25381 gggtccagca ccaccgccca ccgcgccgcg tgctcccgca gccgggccgc cgcccggcgc
    25441 gcgtcctcgt cggtccgcgc caccgggggc tcctccacgt cgcccggctc gatcgcggtg
    25501 accgagagcc gcttgaggcc ccggtcggcg ccgacgaact ccgcgacgta gccgtccgcc
    25561 gggtggccga gcaccgccgc cggggtgtcg tactgctcga tgcgcccccg gccgtagacg
    25621 gcgatgcggt cgccgaggcg gaccgcctcc tcgatgtcgt gggtgaccag cagcacggtg
    25681 gtgcccagcg cgcgctggat ggcggtgaac tcgttctgca gccgctcgcg caccaccggg
    25741 tcgaccgcgc cgaacggctc gtccatcagc agcaccggcg ggtccgcggc cagcgcccgc
    25801 gcgaccccga cccgctgccg ctggccgccg gagagctgcg ccggatagcg gtccgcgaac
    25861 tcggccgggt ccagccccac cagctccagc agctccttcg cgcgggcccg cgccctgccg
    25921 cgcctccacc ccgccagcgt cggcaccgtc gccgtgttgt ccagcaccgt gcggtgcggg
    25981 aagaggccga cctgctggat gacgtaaccg atacggcggc gcagctggac cgggtcgacg
    26041 gccatgacgt cctccccgtc gaccaggacg cggcccgagg tcggctcggt gaggcggttg
    26101 accatcatca tcgtggtcgt cttgccgcac ccggacgggc ccaccagcgt caccagttca
    26161 ccccggccca cctcgaagga gagcccgtcg accgccacgg tcccgtccgg gtagcgcttg
    26221 gagacgtcct cgaagcggat catggcgttc acgctagccg cgccccagag cctccgccgc
    26281 ccggtggcac ccgtccggcg gcgctcggcg gccctgtgct gaactgggcc cggggcacca
    26341 cccgcaccac cgcaccaccg ccaggggaga gaacgtgacc gacacccgca ccgccaccta
    26401 ccgccagccc ggcgtcgtcc tcaccgacca ccgcttcagc gtgcccctgg accacgacga
    26461 gcccgacggc gagcggatcg agctgtacgg ccgcgaggtg gtcgccgccg aacgcgaggg
    26521 catgccgctg ccctggctcc tctacctcca gggcggcccc ggcttcggcg cccaccgcct
    26581 cgtcggccgc ccgcactggc tcggccgcgc cctcaccgag ttccgggtcc tcctcctcga
    26641 ccagcgcggc accggcgcct ccaccccggc gagccgccag acgctcccgc tgcgcggcgg
    26701 ccccgaggag caggccgact acctcaccca cttccgcgcc gactcgatcg tccgcgactg
    26761 cgaggcgatc cgccccggcc tcaccggcgg cgccccctgg acggtcctcg gccagagctt
    26821 cggcggcttc tgcaccacca cctacctctc caccgccccc gaaggcgtcg ccaccgccct
    26881 gttcaccggc ggcctcccct ccctcgacgc ccacgccgac gacgtctacc gcgcggccta
    26941 tccccgcgtc acccgcaaga acgaggcgca ctacgcccgc tatccgcagg acgtggagcg
    27001 cgcccgccgc atcgccgccc acctgctgga gcggccggtg gaactccccg gcgggtacct
    27061 gctgaccgcc gaggcgttcc agtcgctcgg catcctgctc ggctccggcg acggcagcca
    27121 ccagctccac ttcctcctgg aggacgcctt cgtccgcgtc cccggcggcc acgccctctc
    27181 cgacgccttc caggaacagg tccgcgccca cctctcgtat gccgccaacc ccctctacgc
    27241 cctcctccac gaggccatct acgcccagga cgggcggccc accgcctggt cggccgagcg
    27301 ggtgcgcggc gagttcccgc gcttcgacgc ggcccgcgcc ctcgccgggg acgaacccgt
    27361 cctcttcacc ggcgagacca tccacccctg gcagttcacc gccgaccccg ccctgcgccc
    27421 gctgcgcgag accgccggcc tcctcgccgc ccgcaccgac tggaccccgc tctacgaccc
    27481 ggagcggctc gccgccaacg aggtccccgc cgcggccgcc gtctaccacg acgacatgta
    27541 cgtcgacacc gccgactcgc tgcgcaccgc cgccgccgtc cgcggcctgc ggccctgggt
    27601 caccaacgag ttcgagcacg acggcgtccg cgccggcggc ccccgggtcc tggaccgcct
    27661 cctcgccctc gcccgcgacc gggcctgaac ccgggcgccg acggggcgcg cccggcgtcc
    27721 cgccgtccta cgctggcccc atggccgaac agctcgcccc gatgcccgag gactggcagc
    27781 gcgccctcgc ggtcgtcgcc caccccgacg acctggagta cggctgcgcg gccgccgtcg
    27841 cccagtggac cgacagcggc cgggaggtcg cctacgtcct ggcgacgcgc ggcgaggccg
    27901 ggatcgacag cctcgaaccc gccatcagcg gcccgctgcg cgaggcggag cagcgcgcct
    27961 cggccgaggt ggtcggcgtg ggctccgtgg agttcctcgg ccaccgcgac ggcgtgatcg
    28021 agtacggccc cgcgctgcgc cgcgacatcg ccgccgcgat ccgccgccac cgccccgaac
    28081 tggtcatcac cctcaaccac cgcgacacct ggggcggcac ctaccgcaac acccccgacc
    28141 acgtcgccgt cggccgcgcc gcgctggacg ccgcagccga cgcgggcaac cggtggatct
    28201 tccccgagct gggcgccgag ggcctggtcc cgtgggacgg cgtccgctgg gtcgccgtct
    28261 tcggcagcga ccggcccacc cacgccgtgg acgcggaacc cggtctggaa cgcggcatcc
    28321 ggtccctgct ggcccaccgc acctacgtcg aggcgctcac cgaggaggac ccggagcagt
    28381 actgccggaa cctgctgacc gagggcgtcc ggcactccgc cgaccgcttc ggcggccggc
    28441 ccgccgtcac cttcgaactc ttcccctgct gagccccggg cggtaccggt ccgcttgccg
    28501 tagcggcacg tccccttgcc gatacggcac catggctcca tgagcccccg cgcgcaccgc
    28561 cccgccctgc ccgagcccac cccgcccccg gccgacaccg acaccgtcct cgccggggtc
    28621 ggcccgcgcc tgcgcgccct gcgcaaggag cggggcgcca ccctcgccgg gctctccgcc
    28681 gccaccggca tctccgtcag caccctctcc cgcctggagt ccggcaaccg gcgccccagc
    28741 ctggagctgc tgctgcccat cgccgccgcc cacgacgtcc ccctcgaccg cctggtcggc
    28801 gcccctccgg cgggcgaccc gagggtccgc ctggaaccca tcgaacaggg caaccgcacc
    28861 gtcatcccgc tcagccgccg ccccggcggc ctccaggcgt tcaagtgggt gctgcgcccg
    28921 ggggaggggt gcgaccccgt cgaggaacag cgcacccacg aggggtacga gtggctgtac
    28981 gtgatctccg gccggctccg gctgctcctc ggcgagcacg acttcgaact gggggagggg
    29041 gaggccgccg agttcgacac ccgcctgccg cactggttcg gtgccatcgg cgaccaccct
    29101 gccgaggtcc tcagcctctt cggcccgcag ggggagcgga tgcacgtacg ggcgcggccg
    29161 aagtcggcgc ggtgaggtgc gtcccggccg gtgatcgatg ggcgagaacg gttcccctgg
    29221 gccaagcgac cgcttagtat gcggcggagt ccggtgtgcc ggacccagac ccgcgacacg
    29281 taccgcagtg gaggcccgca atgcaggcat ggcaagtgca ccggaacggt gagccccgcg
    29341 aggtgatgag cctggccgac accgcccgcc ccgagccggg ccccggccag gtccgcctca
    29401 aggtccgggc cgccgacgtc aacttccccg acgccctgct ctgccggggt cagtaccagg
    29461 tccgcccgcc gctccccttc accccgggtg tggagatctg cggcgagacc gaggacgggc
    29521 gccgggtgct cgccaccacc gccctgccgc acggcggctt cgccgagtac gcgctggccg
    29581 acgaggccgc gctgctgccc gcccccgacg ccctcgacga cgccgaggcc gccgccctgc
    29641 acatcggcta ccagaccggc tggttcgggc tgcaccgcag ggcgcacctc caggccggcg
    29701 agaccctcct ggtgcacgcc gccgccggcg gcgtcggcag tgccgccgtc cagctcggca
    29761 aggccgcggg cgcccgcgtc atcggcgtcg tcggcggggc cgacaaggcc cgcgtcgcgc
    29821 aggaactcgg ctgcgacctg gtcatcgacc gccgcgagga cgacctggtc gccgccgtca
    29881 aggaggccac cggcggcaag ggcgccgacg tggtctacga cccggtcggc ggcgacgcct
    29941 acaccaagtc cgccaagtgc gtcgccttcg aagggcggat catcgtcgtc ggcttcgcca
    30001 gcggcaccat ccccgccccc gccctcaacc acgccctggt gaagaactac tcgatcctcg
    30061 gcctccactg gggcctgtac gccgtcaagg accccgcctc catcggcgcc tgccacgccg
    30121 ccctcaccga actcgccgcc aagggcgccg tcaaacccct ggtcagcggc cgcgtcccgc
    30181 tcgccgaggc cgccgacgcc gtccagcggg tcgccgacgg caccaccacc ggacgcctcg
    30241 tcgtcctccc ggaaggagcg gccgcatgac cgacgccgac gacctccgcg cccgtacccg
    30301 cgccctgctc gccgaccgtc cgcccgccac cacctcccgg gccgacttcc tcgccgcccg
    30361 cttcgacgcg gggctggcct gggtccacta cccggagggg ctcggcggcc tcggcgccgc
    30421 ccgcagcctc cagtcggtgg tcgacgccga actggccgcc gccggcgccc cggacaacga
    30481 cccccggcgg atcggcatcg gcctgggtat ggccgcgccg accatcctgg cctacggcac
    30541 cgaggagcag aagcgccgct tcctgcggcc gctctggctc ggcgaggagg tctggtgcca
    30601 gctcttcagt gaaccggggg ccggctccga cctcgccgcg ctctccaccc gcgccgtcct
    30661 cggtgacgac ggcgtgtgga ccgtgaccgg ccagaaggtg tggacctcca gcgcccacct
    30721 cgcccgctgg gccatcctca tcgcccgtac cgaccccgcg cagcccaagc accggggcat
    30781 cacctacttc ctctgcgaca tgaccgaccc cggcgtcgag gtgcggccgc tgcgccagat
    30841 caccggcgag gccgagttca acgaggtctt cctcaccgac gtccgcatcc ccgactccca
    30901 ccgcctcggc gaggtgggcg acggctggca ggtcgcccgc accacgctga tgaacgagcg
    30961 cgtctccatc ggcggcagca ccggcgggcg cgagagcggc atgatcgcgc cgctcgcccg
    31021 cacctggcgc gagcgcccgg aacggcgcac ccacgccctg caccagcggc tcgtcacgct
    31081 ctgggtggag gccgaggtgg cccgcctcac cggcgaacgc ctgcgccagc agctcgccgt
    31141 gggccagccg ggccccgagg gcagcggcct caagctctcc ttcgcccgcc tcaaccagca
    31201 gatcagcggc ctggaggtgg aactcctcgg cgacgagggc ctgttgtacg acgactggac
    31261 catgcgccgc cccgaactgg tcgacttcac cggccgcggc cccggctacc gctacctgcg
    31321 ctccaagggc aacagcatcg agggcgggac cagcgaggtg ctgctgaaca tcgtcgccga
    31381 acgcgtcctc gggctgccca ccgaaccgcg taccgacaag gacgtcgcct ggaaggacct
    31441 cgcccgatga gcgccacccc ctccctgctc gccaccgaga ccgaggacga cctgcgggcc
    31501 gccgtccgtt ccctcctcac cacccactcg gccgccgacc gggtgctggc ccgcgccgag
    31561 agcggcgccc cgtacgaccg cgagctgtgg aagaccctca ccggctccat gggcctggcc
    31621 gggctgctcg tccccgaggc cgacggcggc cagggcgcgg gccaccggga agccgccgtc
    31681 gtggtggagg agctgggccg cgcggtggcg cccgtgccct acctgaccgg agccgtcgtc
    31741 accccggcca cgctgctcgc cctcccggag cgcacggccg aggtctcggc cctgctcgcg
    31801 gaggtggccg ccggttcggc cgtcgccatc ctcgccgtcc cgctcaccac cgccccgggc
    31861 gacccgctgc ccgaggtcac caccgacggc ggcggactgc acggcaccgt ccgctccgtc
    31921 gccgacgccg ccggggccga cgtgctgctg gtcgccgccg actcggggct gtacgccgtc
    31981 ccggccggcg cgccgggtgt gacggtcacc ccgctcaccg ccctcgacct gacccgcccg
    32041 ctcgccgccg tacagctgga cggcgcccga ggcaccctgc tcgctccggc cgccgacgcc
    32101 gcccccgccg tacgggccgg gctgctctcc ggtgccggac tgctggcgag cgagcagctg
    32161 gggctcgccg aatggtgcct gaccgagacc gtccggcacc tgaaggaccg ccaccagttc
    32221 aaccggccgc tcggctcctt ccaggcgctc aagcaccgcc tcgcccagct ctggctggac
    32281 gtcgcgggca tccgcccggc cgcgaccgcc gccgccgacc tcctcgccac cggcgagggc
    32341 ggccccgccg aggcgcaact tgccgtggcc gtcgcccagg tgtacgcctc gccggtcgcg
    32401 gtccgcgccg ccgaggaggc gttgcagctc cacggcggga tcggcatgac ctgggaacac
    32461 ccggtccacc tctacctcaa gcgggccaag ggcgactccg tcgccttcgg cggcgccggg
    32521 cgccacggcc aggaggtcgc ccgcctcgcg gagctgcccg cgccctgaac cgacctcccg
    32581 caccgccccc cggcgtaccg cccggcccac cgaaaacccc aggtgggccg ggcgtttcgg
    32641 tcctcgtgcc gctcatgcat aattgcgcat cggacgcaat aaccgaggat cttcaaaagg
    32701 gtccacgacc tggggtggaa tgcgcatgac gagcaggacc gaccgccgac ccgtacgtct
    32761 ggccggaacc ctcgcggcga ccgcggccct caccgtcgcc gccacctcct gctccgcccc
    32821 cggtggcggc accgacgcca agggctccgc gaccggcacc gccgtcgtcg gcatcgccta
    32881 cgaaccggac agcctcagcc ccctcctcgg ctacggcaag gacggcaact ccaagatctt
    32941 cgacgggctc ctcacccacg acgagaagct cgacctccgg cccgccctcg ccaccgaact
    33001 ccccgagatc tccgaggacg gccgcaccta caccttccag ctccgcgagg gcgtcacctt
    33061 caccgacggc aagcccttca ccgcccgcga cgtggtcttc acctacgaga cgatcctcga
    33121 cccgaagacc aacaacgcca gccgcaccga actcgacgcc gtcgagagcg tcgaggccaa
    33181 gggcgaccac accgtcgtct tccacctcaa gtacccctac gcgcccttcg ccgagcgcac
    33241 cgtcctgccc atcgcccccg cccacatcgc cggcgaacag gacgtcaaca ccggagactt
    33301 caccacgaag ccgatcggca ccggccccta cgaactggtc agctggtcca agggcgagaa
    33361 gctcaccttc aaggccaacc ccgactactg gggcggtgcg ccgaagatca agaacttcac
    33421 catggccatc atcaaggacg acgacgtgcg cgccacccgg ctgcgctccg gcgacctcga
    33481 cggcgccatc ctcccgccca acctcgccaa ggcgttcaag gacggggaca ccgccaccta
    33541 cgccgccaag agcttcgact accgcgtcgt caccctgccc accggcaaca aggtcaccgg
    33601 cgacaccgac atccgccgcg ccctcgacct cgccgtcgac cgcgaggcca tggtcgactc
    33661 catcctcgac ggcgccggca agcccgccta cgggcccgtc cccaccgaca gcccctggtt
    33721 caccgagggc accgaacgcg cccacgacct gaaggccgcc gccgatctcc tcgacgaggc
    33781 cggctggaag aagggcaagg acggcgtccg cgccaaggac ggcgtccgcg ccgccttccc
    33841 gctctggtac ctctccggcg acaagctccg ccaggaccac gccctcgcct acgcctccga
    33901 cgccaagaag cttggcgtcg aggtcaaggt ccaggccggc acctgggagg tcatccagcc
    33961 ccggatgccc aaggacgccg tcctcgccgg cggcggctcc ccggccgacc ccgacttcga
    34021 ccagtacacc ctgctcaagt cctccctcgc cggggacggc ttcaacaaca tggcccacta
    34081 cgacaacccg gccgtcgaca aggccctgga gaagggccgc cgcagcgggg agcacgccga
    34141 gcgccaggcc gcctacgaca ccgtccagcg cgaactggtg aagaaccccg gctacacctt
    34201 cctcacccac atcgaccacg tctacgtcgt cgacaagcgc ttcggcaccc tcaccaccca
    34261 ggtcgaaccc cacgaccacg gcctcgcctc cggcccctgg tggaacgtcg aggactggaa
    34321 gcccgccaag tgaacaaggc ccggcccggc ctgccctgga tacccatggc gcgcatgacg
    34381 gggcggcggc tgctcttcgc cgtgcccgtc ctgctggccg tcaccttcgc cgtcttcgcc
    34441 gtcgccgacg cctccccgtt cgaccccgtc aaggcgtacg ccggggccgc cggactcacc
    34501 gcctcgcagg agaacctcga ccagctccgc gccaacctcg gcgtcgacca gccgctcgcc
    34561 gtccgctggt gggagtggat caccggcgcg ctcaccggcg acctcggcca ctccgccgtg
    34621 atgcgccagc ccgtcgccga cgtcatcgcc gaacgcatcg gctggtcggt cctgctggcc
    34681 gccctcgcct tcgtcgtggc ggtcctcgcc ggcaccaccc tcggtgtcct cgccgcccgc
    34741 cgccggggct ccctcgtcga ccgggccgtc acctccctcg cgtacaccct ggaggccgcg
    34801 cccaccttct ggctcggcct gctcgccgtc tggctcttcg ccctccagct cggctggctc
    34861 ccggccggcg gcctcaccga caccggcagc accaccgtca ccgccgggca gctcaccacc
    34921 cacgtgatcc tgcccgccgc cgtcctggcc gcctcccagc tcccgtggtt cgccctctac
    34981 gtccgccagg gcgtcggcga cgccctcgac gaggacccgg tacgcggcgc ccgcgcccgg
    35041 ggcctggccg aacacaccgt gctcctcggc cacgcgctgc gctccggact gctccccgtc
    35101 ctcaccctca tcggctcgcg cgtccccgaa ctcatcaccg gcgccctgct ggtggagacc
    35161 gtcttcagct ggcccggcat cgccgccgcc accgtgcagg ccgccaccgc cgtcgacttc
    35221 ccgctgctcg ccgccaccac cgtcctcgcc accgccgccg tcctgctcgg caacctcgtc
    35281 gccgacctgc tgtacggcct cgccgacccg agagtgggct tcgatggctg acctcgccct
    35341 gcccaccgcc cccggccgcg tcgcccgcac cgcccgcacc tggaaactgc ggatcagcgc
    35401 caccctcgtc gcgggcttcg tcctcgccgt cctcctcgtc ccgcccctgg tgggcctcga
    35461 cgaacaggcc gtcgacctcg gcgcgaaact ccttccgccc tccctcgacc accccttcgg
    35521 caccgacgac gtcggccgcg acctgctcct gcgctgcgtc tacgggctgc gggtctccct
    35581 cctcgtcggc gtcgtcgccg ccctcgtcgc caccgtcctc ggcaccgccg tcggcgcggc
    35641 cgccggcgcc ctcggcggct ggaccgaccg gctcgtcatg cgctgcgtcg acgccttctc
    35701 ctccgtcccc cacctcctcc tgggcatctt catcgtcgcc ctcttccgcc ccggggtgtg
    35761 gcccgtcgtc gtctccgtcg gcctcaccca ctgggtctcc accgcccgca tcgtccgcgc
    35821 cgagatcctc tccctgcgcg cccgccccta catcgacgcc gccgtctccg gcggcgcctc
    35881 ccgcctcagg ctcgcccgcc gccacctgat ccccggcgtc ctcccgcagg ccggactggc
    35941 cgccgtcctg atgatcccgc acgccatctg gcacgaatcg gccctctcct tcctggggct
    36001 gggcctgccc acccaccagg ccagcctcgg caccctcgtg cagagcgccc ggggcaccct
    36061 gctcgccggt gactggtggc ccacgctctt cccgggcctg ttcatcatcg tgccgaccct
    36121 cgccatcgcc gggctcgccg gagcctggcg cgaacggctc aacccccggc gccgatcgga
    36181 gctgatgctg tgaccgtcct gtccgtacgc ggcctcaccg tgcggttccg gatgcgcgag
    36241 agcgcccccg tccgcgccgt caccgacgtc tccttcgacc tcgccgcggg ggagtgcctc
    36301 gccctcgtcg gggagagcgg ctgcggcaag tccgtcctcg cctccgccct gctcggcctg
    36361 ctccccggca acgccgagac cgccgggtcc gccctgctcg ccggggtcgg cgacgacccc
    36421 gccaccgacc tgatcgccgc cgacgaggcc accctcgccc gcaccgtacg cggccgccgc
    36481 gtcggcctcg tcccgcagag ccccgccgcc catctcaccc cggtccgcac cgtccgcgcc
    36541 cacctcaccg agaccgtccg ccgcctcacc ggcacccggg gccgcgacgc cctgcgcacc
    36601 gccaccgagg ccgccgccgc ccgcgtctcc ttccccgcgg gccacctcga ccggcacccc
    36661 cacgaactct ccggcggcct cgcccagcgc gccgccaccg ccctcgccct cgtcggtgac
    36721 gccccgctgc tcctcgccga cgaacccacc accggcctcg accgcgacct ggtcgagcgc
    36781 accgtcgacg aactccgccg ccacaccggc gccacccgcg ccctgctgat gatcacccac
    36841 gacctggcgg ccgccgcccg catcgccgac cgggtcgccg tcatgtacgc cgggcgcctc
    36901 gtcgagatcg ccgacgccga cgccttcttc ggcaccccgg gcccccgtca cccctacgca
    36961 cgcggtctcc tcgacgccct ccccgaacgg gccttccgcc ccgtccccgg gcgcccgccc
    37021 gaactcgccg cactgcccgc gggctgcgcc ttcgccgccc gctgcgccca cgccgacacc
    37081 gcctgcgcga cgcagccgcc cctcaccggc ggactcgcct gccaccaccc ccacacggcc
    37141 cccgccgacc tcgtccaccc gccccaggcc gcggaggcac ccggtgcttg aactcctctc
    37201 cctcaccgcc ggatacgacc gccgcgcccc cgtcgtccgc gatgtcaccc tcaccctcgc
    37261 ccccggcgag gccgtcggcc tcctcggccc cagcggctgc ggcaagtcca ccctcgcccg
    37321 cgtcgccgcc ctgctccacc ggcccgactc cggccgcgtc gtcatcgacg gcgaaaccgc
    37381 ccggggttac cgccaccgcg ccccacgcgc acagcgcacc gccttcggcg tcgtcttcca
    37441 gcagccccgc cagtccgccg acccccgcct gcgcctcgcc gacctcatcg ccgaacccct
    37501 gcgcgccacc ggccgcccgg agggcgccgc cgacaaggcc gccgagacgg ccgacacggt
    37561 cggcctcgga ggtgacctgc tcggccgccg cccccacgag gtcagcgacg gccagctcca
    37621 acgcgcctgc ctcgcccgcg cgttgatcct ccgcccgcgc tacctcgtct gcgacgagat
    37681 gaccgccatg ctcgacgcct ccaccaccgc cgccctggtc ggcgtcgtcg aggagtaccg
    37741 ccgcgagacc ggcgccgcgc tgctcgccgt cggacacgac cgggtgctgc tcgaccgctg
    37801 gtgcgaccgc accgtcgaat ggtccgaact cggctcccgc cacgacggct tggccaccgc
    37861 caagcccccg gccgaacgat caccctcggt acgctgaccg gtcacggatc gtcagtcacc
    37921 cggacggcgg ccatgccgtt caccggcccg ccgctcaccg cgcgccacac tggccgccga
    37981 cagccacgga gtcggcgtgg cggtgaggag acttccgatg gcgattaccg tttccgtggc
    38041 gctgctgctc ctgatcctgg cggtgatctt catccgcagc ggcggactga agacctcgca
    38101 cgcgatcatc tgcgtcctcc tcggcttcct cctcgccgga acctccgccg ccccgaccat
    38161 ccaccacacc ctggtctcca ccgccaacat gatcaacggg gtgggcaggt agaccccgta
    38221 cgcgccacca gccgttccgc gagccactgc gcgaaccccg ccagccggtc ccgctcaggt
    38281 ccgcccctcg ccctccggaa tccgtggcga cgcccccaga acaacgcctc gacgagcagc
    38341 agttgagccc agcgtgtcac ccggtcgcgg tcgaggccgg cggcctccgc gaagacggcg
    38401 agggtgcggt gggcgtcctt gagggggtcg gccgaggaga gcaggaccgg ggtgcgcgtc
    38461 ttgagcaggg tgccgccgtc gtacgccggg tcgcccgcca ggcccttcgg gtcgacggcc
    38521 agccagggtt cgcggccggc gcgcaggatg ttccgggggt gcaggtcccc gtggaccatg
    38581 gtggccggcc ggtaccgtgc cgcctcccgt acggtcgcca gggcggcgtc cagtgtgtgg
    38641 ccgggcagcg cgtgcggcac ctcggccgcg tccttgagca gtcgcgcctc ccagccggcg
    38701 gcgcggtccc gcagcagggg caggccgggc ggggccggga cggccagccg gtggctcagc
    38761 agccccgcga cctcggccac ctcgtccccg tcggcgacct cggcgaggct cgacgctccg
    38821 gcgcgttcca gcagcatcgc gtaccgcgcg tcgtcccgct cgtggagcag caccgccccg
    38881 tgcccgcccc agacggtgaa ggcgtccggt tcgtggacgt tgcccgggtg cgggaacgac
    38941 accttgatca cgcccggcgc accacccgcc gccctccgca ccgggaccac caggccgacc
    39001 ccgccgtgca gcacctcacc ctccggcacg cactcccagc gctccaggag ttccgcgacg
    39061 gtcgccggca gcccggcgag ccaggcggcg ccggtgtcgc cctcgcgggc cacggtggtc
    39121 cggacgaact ggggaggaag ggtgatcacg cggtcacgat agaccggcgc cgggctccgg
    39181 agcgggcgaa cggccgctgt tgcggggccg gttcgggctc agccgacggt cccggtcgtg
    39241 ccgtcggtga gttcccggag gatgtccgcg tgtcccgcgt gccgggcggt ctcctcgatc
    39301 atgtgcgtga gaatccagcg cagcgacacc tggcccagcc aggcgtgcgg caccacatgg
    39361 tcgagcgggt acccggccgc gctctcccgt gaccgggcgc aggccgcctc gtacgccgcg
    39421 atcagaccgg cgaccgtctc ctcctcgtcg acggcgaacg agacctcggg gtcgggcagg
    39481 accgagggct gctgcccgag gacccgtacg aaccagttgt cctcgaccag cgccaggtgc
    39541 ttcagcagac cggccatcgt ggtcgacgag gggacgtggc gacgccgcgc ctgctcctcc
    39601 gtcagcccgg cggccttgcg ccgcacgaca ccgcgctggt agtcgagaaa ggtctccagc
    39661 acctggcgtt cgccacccgc cacggaaccc gtcacggcca gaacatccgc atccgtcatg
    39721 cgcatacgct gacaggggag gcggcccgtg ccaagggcgc ggtgcggacc gttcagggcg
    39781 ccggggccac cagccgcttg agcgcccacg ccgccacggg ccggtacagc accacgacgg
    39841 gcagggggcc cgagacggtc agccgcgtgc ggctgccgcc cccgggcgcg gccgtcacct
    39901 cgtggccgag ccggagcacc agcggcccca gcccgacgcg ccacgtccac ctccgctgct
    39961 cctcgtccac ccgctccacg gtgaaccgga cccgcacccc ggcgtacgag aagacccgcc
    40021 cgcgcacccc cggcgcgatc cggccggcgt ccgtctccac ccgcctgatg tgcggggccc
    40081 actgcgacca gagcgcgggc cgcgcgtacc tctcccacgc ggtctccggc gcgacgggac
    40141 ccgcacggct caccgtgcgg gtcgccacag cgcccctcgg ccgtcccggc tcccgcccat
    40201 gaccagctcc tccgtgtcgt gccgccccca ggtcgaggac agcacgcccc ggctctcccg
    40261 gccagccggg gaccggctca ggcggcgagc atccccgagg ggtcgaggac ctggcggatg
    40321 gcgcggcccg aggccagctc ctccagcgcg gtgttgacgc cgccgagcga cacggtgccg
    40381 gtgtgcagca gctcgaccgg catcagcccg gaccgccaca ggcccaggaa gcgggggatg
    40441 tcccggcgcg gcaccgcgtc ccccatgtac gagccgagca ggctcttgcc ctcaccggag
    40501 aaggccagcg ccggcacctc cagcgaccgg ccgggcgccg gcagccccac cgagacggcc
    40561 ttgccgcccc ggccgaccgc cgccagggcc gccgccatca ccccggggct gcccaccgcc
    40621 tccacggcca cgtccgcccc gccgccggtc agctcccgta ccgcctccgg ggcctcctcg
    40681 ggggtgaagg cgtgggtggc gcccagccgc agggccagtt cgcgcttccc ggcgaccggg
    40741 tcgacggcga cgcggaccga ggcgcccgcc gcccgcgccc ccagtacggc cgccagcccg
    40801 actccgccca ggccgaagac gaccgcgctc tggccgggac gcagtgcggc cgtgttgacg
    40861 acggccccgg cgccggtcag caccgcgcag ccgaacatcg aggcgacggt gaacggcacg
    40921 tccgccggga tcggcaccac cgactcctgc gcgaccaccg cgtactcgga gaacgccgag
    40981 acccccagct gatgatggac cggctgcccg gccgcgtcgg tgagcagcgg cgggccgtgc
    41041 agcaggcccc cggagccgtt ggcctcggcg gcccgtgcgc acagggccgg gcggccct
//
