LOCUS       NZ_VOGX01000034        11368 bp    DNA     linear   CON 15-OCT-2024
DEFINITION  Streptomyces albidoflavus strain 77
            scaffold11_cov50_3627731_4779920, whole genome shotgun sequence.
ACCESSION   NZ_VOGX01000034
VERSION     NZ_VOGX01000034.1
KEYWORDS    WGS; RefSeq.
SOURCE      Streptomyces albidoflavus
  ORGANISM  Streptomyces albidoflavus
            Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
            Streptomycetaceae; Streptomyces; Streptomyces albidoflavus group.
REFERENCE   1  (bases 1 to 1152190)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Draft Genomic Sequences of Streptomyces misionensis and Streptomyces
            albidoflavus, bacteria applied for phytopathogen biocontrol
  JOURNAL   Microbiol Resour Announc (2019) In press
REFERENCE   2  (bases 1 to 1152190)
  AUTHORS   Pylro,V., Dias,A., Andreote,F., Varani,A., Andreote,C., Bernardo,E.
            and Martins,T.
  TITLE     Direct Submission
  JOURNAL   Submitted (31-JUL-2019) Biology, UFLA, Universidade Federal de
            Lavras, Lavras, MG 37200000, Brazil
COMMENT     ##Genome-Assembly-Data-START##
            Assembly Date                     :: 15-JUL-2019
            Assembly Method                   :: SPAdes v. 3.12
            Genome Representation             :: Full
            Expected Final Version            :: Yes
            Genome Coverage                   :: 36.0x
            Sequencing Technology             :: Illumina MiSeq
            ##Genome-Assembly-Data-END##
            ##Genome-Annotation-Data-START##
            Annotation Provider               :: NCBI RefSeq
            Annotation Name                   :: GCF_007896905.1-RS_2024_10_13
            Annotation Date                   :: 10/13/2024 04:20:50
            Annotation Pipeline :: NCBI Prokaryotic Genome Annotation Pipeline
            (PGAP)
            Annotation Method :: Best-placed reference protein set; GeneMarkS-2+
            Annotation Software revision      :: 6.8
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA
            Genes (total)                     :: 6,551
            CDSs (total)                      :: 6,456
            Genes (coding)                    :: 6,343
            CDSs (with protein)               :: 6,343
            Genes (RNA)                       :: 95
            rRNAs                             :: 7, 7, 7 (5S, 16S, 23S)
            complete rRNAs                    :: 7, 6, 5 (5S, 16S, 23S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 71
            ncRNAs                            :: 3
            Pseudo Genes (total)              :: 113
            CDSs (without protein)            :: 113
            Pseudo Genes (ambiguous residues) :: 0 of 113
            Pseudo Genes (frameshifted)       :: 34 of 113
            Pseudo Genes (incomplete)         :: 81 of 113
            Pseudo Genes (internal stop)      :: 8 of 113
            Pseudo Genes (multiple problems)  :: 8 of 113
            CRISPR Arrays                     :: 1
            ##Genome-Annotation-Data-END##
            ##antiSMASH-Data-START##
            Version                           :: 8.dev-cf2fc5ee(changed)
            Run date                          :: 2025-09-13 03:41:23
            NOTE :: This is a single region extracted from a larger record!
            Orig. start                       :: 804582
            Orig. end                         :: 815950
            ##antiSMASH-Data-END##
            REFSEQ INFORMATION: The reference sequence is identical to
            VOGX01000034.1.
            The annotation was added by the NCBI Prokaryotic Genome Annotation
            Pipeline (PGAP). Information about PGAP can be found here:
            https://www.ncbi.nlm.nih.gov/genome/annotation_prok/
FEATURES             Location/Qualifiers
     region          1..11368
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="RiPP-like"
                     /region_number="2"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     cand_cluster    1..11368
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     protocluster    1..11368
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="False"
                     /core_location="[5000:6368](+)"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..6368
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     misc_feature    complement(198..212)
                     /note="TFBS match to SypG, Regulator of biofilm formation
                     and host colonization, confidence: weak, score: 15.61"
                     /tool="antismash"
     gene            277..1332
                     /locus_tag="FRZ02_RS21855"
                     /old_locus_tag="FRZ02_21855"
     CDS             277..1332
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1011: transport
                     system permease protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894130.1"
                     /locus_tag="FRZ02_RS21855"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21855"
                     /product="iron ABC transporter permease"
                     /protein_id="WP_146582353.1"
                     /transl_table=11
                     /translation="MSAARTAAPVLRRGRTGTRVKAAVLVLLALAAGVAGLVAGPAVTA
                     ADVAEVFAGGGDPLARHIVLNLRLPRALVALTAGACLALAGLVLQSALRNPLAGPEVTG
                     VTPGAVLGAVTATGLGLAGWQSPTAVVVAACLGGCAGAGLLWLLAGRERGDPEQTAVHG
                     VLVSAVLTGGTAVVLLIAPGELGSVVQWLVGSTEGRVWRHWELLWPWALCWGAAAWLLA
                     GPLTLLRCGDEQAAALGLDTGRARAAALACAVALTAGAVSAVGALGFVGLLVPHVALAV
                     FGADLRATLPGAALLGAVVVGGADAGAQLLSRALAQALDADRLTVPVGALTTCAGAALL
                     LVVARRRADLR"
     gene            1455..2291
                     /locus_tag="FRZ02_RS21860"
                     /old_locus_tag="FRZ02_21860"
     CDS             1455..2291
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1000: ABC
                     transporter ATP-binding protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639452.1"
                     /locus_tag="FRZ02_RS21860"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21860"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_018894131.1"
                     /transl_table=11
                     /translation="MDHREPGAVVAEGLRFGYPGREVLRGVDLRIGAGELVALVGLNGC
                     GKSTFLRLAAGLLRPDAGRVLLDGEEVARLSRRGAARRVALLHQSAPPVPGLTVRQLVR
                     QGRYAARGPLGMLRDGDDAVSARALADAGVADWAGRPVDALSGGERQRVRLAMALAQDT
                     RILLLDEPTTYLDLRHQLEVLQTVVRLRAERGLTVVMVVHDLNHAARFADRIVALRDGR
                     VAADGKPAAIVTPALLAEVLGVEGRVAPDERGGWPVCYPDHPLGAASHLRNENHIH"
     gene            2360..2494
                     /gene="amiA"
                     /locus_tag="FRZ02_RS33530"
     CDS             2360..2494
                     /codon_start=1
                     /gene="amiA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508296.1"
                     /locus_tag="FRZ02_RS33530"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /product="streptamidine family RiPP"
                     /protein_id="WP_008409986.1"
                     /transl_table=11
                     /translation="MEHDKVFAPIADPGQLAHLSATHSNALVENPFDDADEAGAADDK"
     gene            2636..3481
                     /locus_tag="FRZ02_RS21865"
                     /old_locus_tag="FRZ02_21865"
     CDS             2636..3481
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470988.1"
                     /locus_tag="FRZ02_RS21865"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21865"
                     /product="hypothetical protein"
                     /protein_id="WP_146582355.1"
                     /transl_table=11
                     /translation="MTSSRLAPGAGIVTVPGGRPAVRTAEGEFLHLDTGTADLAALTRH
                     LVGGEAAPDAEVARVAAAFEREGHAVRPGPEEGGALTGRTVLVLGDARLTGPLARYAAA
                     EGARTRHATPEHVGRLADGEGADASTVVVWCLDEPAPPALWDAADRLPAHGTAWLRCHR
                     EGAHLWTEPLAAAPGDVTSAHVRLRRLAATSAHRQLAAYWAGHRTPDNGPHPGEAACAL
                     VAALLTADLLAWAAPGPGSGLPARRRLRRVDLRDLTVTEHPVLPVPPVAPLPGRGSGPA
                     "
     gene            3478..5004
                     /locus_tag="FRZ02_RS21870"
                     /old_locus_tag="FRZ02_21870"
     CDS             3478..5004
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010639446.1"
                     /locus_tag="FRZ02_RS21870"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21870"
                     /product="CocE/NonD family hydrolase"
                     /protein_id="WP_146582357.1"
                     /transl_table=11
                     /translation="MTPATTRLATPDGTTLATDLHLPATPGPHPAVLIRTPYDRRAHRA
                     ELRGWAERGFAAVAQDVRGRHGSAGEWHPYRDHEAEDGVATLDWIRAQPWSDGRVVAAG
                     ASYAAYCALAAALCPGARGPDAVIAAVPALGLAETAREPTGPERLWARLGWWAAHGDRR
                     DSAPDALDRALARDPSLPTHLPLTRIADRLDRQLPSWPALWADCRRGRLVAHGSAARLP
                     LLAVGGTRDPFAEDTVALWRGWGGPARLLLGPWGHTLTAETRPGTPGRVDLGALYARWA
                     RAALDGELGPGRRGVIGLAESGRWHHLTDTPTRPEGPEVAGCVWQFGAANGRCLLAGAE
                     FTADPDRPVRSDDLTVPRGAPADRCLLATPPLPRPLDLAGPAEARLTVVADTPRADWAV
                     RVVALDPAGRADPLAFGIVRRDAPPGTPHPVTVPLGTLGRTLAAGTRLRVEIAGHHFPA
                     HARNPHTGEDPVTATRLAASRRTVRSEGSALHLPVAGRPRPVDPVPETCR"
     gene            5001..6368
                     /locus_tag="FRZ02_RS21875"
                     /old_locus_tag="FRZ02_21875"
     CDS             5001..6368
                     /codon_start=1
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: YcaO"
                     /gene_kind="biosynthetic"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010059075.1"
                     /locus_tag="FRZ02_RS21875"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21875"
                     /product="YcaO-like family protein"
                     /protein_id="WP_146582359.1"
                     /sec_met_domain="YcaO (E-value: 4.6e-43, bitscore: 143.9,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTAALPLDALVDPHCGLVRDVAPVPHPEGAPPRYTAMTAHVADAR
                     RFGAWPADRVSLGTTFGDPAGAWTAAVAEAVERYCGNRLPPPGHPDAPRRATAAQLTAE
                     GHQVYGPDDVPAYAPWQYRRPAFPYAPLTPGTPALWARGTENGRDCWAPVALTHLNWRQ
                     GELRALPRTHHLNYAGIATGQGLADAAERALLEVVERDALELWWHLDGPTRGVDPGSVP
                     GLDADLAGSGLEVSIVEMPSEFAPCVAALVHDARRGVHAAGFACRFDPAEAARKAVLEA
                     VHTWVFTLGAEAAGGWVHQAVEAGVLARGLYLDHRADRRYLDDCGEEFAAVRDLGAHVQ
                     AWLDPRLAPLARRFTAPALGTVPVAELAPGSRERLDAALAAGGHRVLTFDLTAEDVAGT
                     ALRVARVLVGGLVPNAPAAFGYYGCPRFATAALARGWRTEPPRAPADFTLAPAPHM"
     gene            6383..7690
                     /locus_tag="FRZ02_RS21880"
                     /old_locus_tag="FRZ02_21880"
     CDS             6383..7690
                     /codon_start=1
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015508299.1"
                     /locus_tag="FRZ02_RS21880"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21880"
                     /product="nitroreductase"
                     /protein_id="WP_146582361.1"
                     /transl_table=11
                     /translation="MTPDATLGHALALARSPRTPARATPPPRRPYPWTGTPLALPATAP
                     DPDGPVDLDHLLRHSLRARPGPGGRFRPAASAGALHPVRAHLLIGPGCTLPPGRYAYDA
                     EVHRVFRRGPAPRGAAPGVIAVLTVTAAHTAAHYGHRAWPLLLLDTGHTAAALALAPKG
                     PGVRVSLDTDAATLAAAAGLPPADRWQRIRPGTETEHPLAAVQVTPRRTQRTAPALDRW
                     AALPLPHRTRTPTRPPARPCGTGRLLELLGAATGTELAWHPVRRPATVTGRALLERRSA
                     DPAALGHPPDGETVARLLHTAATAWPGGPAWCAAVATPAPALLAPGHHTATPYRLARGD
                     ARPSLAHWAAGQLWLADTGAALLAHGCPSDAPASQIRHDHLAAGFAAGTAHAHAAAEGI
                     NARPVGSWQQADLGAALGDTPGLDWVLHGLALGAAR"
     gene            7749..9494
                     /locus_tag="FRZ02_RS21885"
                     /old_locus_tag="FRZ02_21885"
     CDS             7749..9494
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018894136.1"
                     /locus_tag="FRZ02_RS21885"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21885"
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="WP_146582363.1"
                     /transl_table=11
                     /translation="MIPPPELRRAARPAALPLAGATALLALVGATHIGQAVLLALVLAR
                     VARGETAGLPALLAAVAVVVLARALLSRAQRLLAVRAGALVRVRLRDDLLAHLGRTGPG
                     ALSGARAGAVRATLVDGVEGVDAYVSRYLPHLIVTCALPPRLLVAVALVEPYAVAALAP
                     ALLLALAGPRLWDRLLARRGREHWDSYEALAADHLEALQGMATLRAAGAVGRTQARLER
                     RSAALHRATVAKMRVSLADTGLTDLAVQGGTVAAVLVACAAATTGSTTATGTYLLLMLA
                     SECFRPVRDLSREWHAGHLGLSAVDGIAALRHTEGGVPDEGTAPAEWATPPEVRFENVH
                     FTHPGRTPPALAGVAFTAPAGRVTALVGPSGAGKSTLLSLLLRQRDPDAGRITVGGLDT
                     AAYRLDALRRGIAVVSQDTYLFRASVADNLRLARPAATPSQLHEAARAAGIHEELTRLP
                     DGYDTVIGERGATLSGGQRQRLALARALLADAPVLLLDEATSAVDERAEARITRELLAA
                     GRGRTCLLVAHRLEAVRHADHIVVLDHGRVEAAGTHPQLLAAGGLYARLVAAGRTVTPM
                     QQEAA"
     gene            9491..11275
                     /locus_tag="FRZ02_RS21890"
                     /old_locus_tag="FRZ02_21890"
     CDS             9491..11275
                     /EC_number="7.-.-.-"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016887 - ATP hydrolysis activity
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
                     /codon_start=1
                     /gene_functions="transport (smcogs) SMCOG1288: ABC
                     transporter related protein"
                     /gene_kind="transport"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018470983.1"
                     /locus_tag="FRZ02_RS21890"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /old_locus_tag="FRZ02_21890"
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="WP_146582365.1"
                     /transl_table=11
                     /translation="MTPPAPQEPPAGPPTRKALRSLLPVLAAHRAMTARTCAAALVDQA
                     ALVALVTLAAHTVGTAVIDGRPPSTATAALLLALVAVRALATWREMDLSHDLAYRVLAL
                     LRVRVFDGIARSAPARIAGRRSGDLASTALGDVEALEFFYAHALAQLLATGTVFTASAA
                     LLGTREPWLLALLLPAAALLLALPVLDGRGRAARGARTRTALADLSAETVETVDGLREL
                     LAFGALHRRRARLRAYGRRLARAQRAEQSWEAGAAALRDLLVVAAVIGVVAVAGHSAVE
                     GRLHGAWTPAAMALALGALAPVADAAASLGQAGSLRAAAARVRAAAEAPAGAPAPSTPR
                     PLPEGPLGLHLRGVRFGYGSTPVLDGVDLTVRPGETVALVGASGAGKSTCAHLLARYWD
                     PQEGTVTLVPEDGRPPVALRDLADAELRSAVAVVGQEAPLFHGTLAENLLLAAPDAPPD
                     ALDRAVRACGVDVLAAGLPDGLGTAVGERGATLSGGQRARVALARALVAAPRVLVLDET
                     TAHLDHTGDAELAAALAATAPGRATLVIAHRPATVRRADRVAVLEDGRIVEEGTWQELA
                     SAGGALTRLLSREATATA"
     misc_feature    11294..11307
                     /note="TFBS match to ArgR, Regulator of arginine
                     biosynthesis genes, confidence: weak, score: 16.15"
                     /tool="antismash"
ORIGIN
        1 ggtcggcttc ctcgcgccgc acctggcccg gcggctgcgg cccggcgccg acgcggcggg
       61 gctgctcggg tacgcggccg cctgcggcgc cgtcgtcgtg gtctgcgccg acctgcccgc
      121 ccggctcctg ctcgcccccg tcgagacccc ggtcggcgcc tggaccgccc tgttcggggt
      181 gccggtcggt gtggccctgc tcaaatggcg cacgcccgac cgcggttcac cggcccccgc
      241 gcccggcgac cgggccgccc tgcggaaggc cgagtggtga gcgccgcgcg gaccgccgcg
      301 ccggtactcc ggagaggccg gaccggcacc cgggtcaagg cggccgtcct ggtgctcctc
      361 gccctcgcgg ccggggtggc ggggctcgtc gccgggcccg ccgtgaccgc ggccgacgtc
      421 gccgaggtct tcgcgggcgg cggggacccg ctcgcccggc acatcgtgct caacctccgt
      481 ctgccgcgcg ccctggtcgc cctcaccgcc ggggcctgcc tcgccctggc cgggctggtc
      541 ctccagtcgg ccctgcgcaa cccgctggcc ggtcccgagg tcaccggggt caccccgggg
      601 gcggtgctcg gggcggtcac cgcgaccggg ctcggcctgg ccggatggca gtcgccgacc
      661 gccgtggtgg tggccgcctg cctcggtggc tgcgccgggg ccgggctgct ctggctgctc
      721 gccgggcggg agcggggcga ccccgaacag accgccgtcc acggcgtcct ggtctccgcc
      781 gtgctgaccg gtggcaccgc cgtggtgctg ctgatcgccc ccggcgaact cggcagcgtc
      841 gtgcagtggc tggtcggctc caccgaggga cgcgtctggc ggcactggga actcctgtgg
      901 ccgtgggccc tgtgctgggg ggccgccgcc tggctgctgg ccgggccgct gacgctgctg
      961 cggtgcggag acgaacaggc cgccgcgctg ggcctcgaca ccgggcgggc ccgcgccgcc
     1021 gccctggcct gcgcggtggc actcaccgcc ggggcggtct cggcggtggg cgcgctcggc
     1081 ttcgtggggc tgctggtccc gcacgtcgcc ctcgccgtgt tcggcgccga cctgcgggcc
     1141 actctgcccg gcgccgccct gctcggcgcg gtcgtggtgg gcggcgccga cgcgggggcc
     1201 caactgctct cccgcgccct ggcccaggcc ctggacgccg accggctcac cgtccccgtg
     1261 ggtgccctga ccacctgcgc gggcgccgcc ctgctgctgg tcgtggcccg gcgccgcgcc
     1321 gacctgcgat gagccggccg acaccgcgcg cccccgaggc gtaccgaacc acggccgtgc
     1381 gggcgtccgc gccgccggta ccgacgagtg acggccctgc ccggcgagcg cgggcggggc
     1441 cggaaggagg agtgatggac catcgggaac ccggtgccgt ggtcgcggaa ggactgcggt
     1501 tcggctatcc gggacgcgag gtgctgcgcg gggtcgacct gcggatcggc gcgggggaac
     1561 tggtcgccct ggtcggcctc aacggctgcg ggaagagcac cttcctgcgg ctcgccgccg
     1621 ggctgctccg tccggacgcc gggcgcgtcc tgctggacgg tgaggaggtg gcgcggctct
     1681 cccgccgggg cgccgcccgc cgggtggccc tgctccacca gtcggcgccg cccgtaccgg
     1741 ggctgaccgt gcgccagctg gtccggcagg gtcggtacgc ggcccggggg ccgctcggga
     1801 tgctccgcga cggggacgac gcggtgagcg cgcgggcgct ggccgacgcc ggggtcgccg
     1861 actgggccgg gcgtccggtc gacgcgctct ccggcgggga gcggcagcgc gtacggctgg
     1921 ccatggcgct ggcccaggac acccggatcc tcctcctcga cgaaccgacc acctacctgg
     1981 acctcaggca ccagctggaa gtgctccaga ccgtggtccg gctgcgcgcg gaacgcggtc
     2041 tgacggtggt gatggtggtg cacgacctca accacgccgc ccggttcgcc gaccggatcg
     2101 tcgccctccg ggacggccgg gtggccgccg acggcaagcc cgccgccatc gtcacccccg
     2161 cgctcctcgc cgaagtgctg ggtgtcgagg ggcgggtggc gccggacgag cggggcggct
     2221 ggccggtctg ttacccagat caccctctgg gggccgcaag ccacttgcgg aatgaaaatc
     2281 atattcatta atgtccgtgg tgcggcaggc gccacgccgt tcacgtccac cacgcatcga
     2341 accgaatgga gctcaactca tggagcacga caaggtgttc gccccgatcg ccgacccggg
     2401 ccagctggcc cacctctccg ccacccactc caacgccctc gtcgagaacc ccttcgacga
     2461 cgccgacgag gccggtgccg cggacgacaa gtagtcggcc ccggccgccg gtgacggcgg
     2521 ccggctgaca cccgtgacgg gcccgcccgg cgaacccccg ggcgggcccg ttgcgttcgg
     2581 cgccccgcag cgcggcgccg ctcatcccct cgcacttcat ccgacggagg tttccgtgac
     2641 cagcagccga ctcgccccgg gcgccgggat cgtcaccgtc cccggcggcc ggcccgccgt
     2701 acgcaccgcc gagggcgagt tcctgcacct cgacaccggc accgccgacc tcgccgcgct
     2761 cacccgccac ctggtcggag gcgaagccgc ccccgacgcc gaagtggccc gcgtcgcggc
     2821 ggcgttcgag cgcgagggcc acgcggtccg gccgggccct gaagagggcg gcgcgctcac
     2881 cggccgtacc gtcctggtgc tgggcgacgc gcggctcacc ggcccgctcg cccggtacgc
     2941 ggccgccgaa ggcgcccgca cccggcacgc cacccccgag cacgtcggcc ggctcgccga
     3001 cggtgaaggg gcggacgcgt ccaccgtcgt cgtctggtgc ctcgacgagc cggcgccgcc
     3061 cgcgctctgg gacgccgccg accggctgcc cgcacacggc acggcctggc tgcgctgcca
     3121 ccgcgagggc gcccacctgt ggaccgaacc gctcgccgcc gcccccggcg acgtgacctc
     3181 cgcccacgtc cgcctccgcc gcctcgccgc cacctccgcc caccgccagc tcgccgccta
     3241 ctgggccgga caccgcaccc ccgacaacgg cccgcacccc ggcgaggccg cctgcgccct
     3301 ggtcgccgcc ctcctcaccg ccgacctcct cgcgtgggcc gcgccgggcc ccggctccgg
     3361 gctccccgcg cgccgcaggc tccgccgcgt cgacctgcgc gacctcaccg tcaccgaaca
     3421 ccccgtactg cccgtaccgc cggtggcccc gctgcccgga cgggggagcg gcccggcatg
     3481 acgcccgcga ccacccgcct cgccaccccc gacggcacca ccctcgccac cgacctccac
     3541 ctccccgcca cgccgggccc ccaccccgcc gtgctgatcc gcaccccgta cgaccgccgc
     3601 gcccaccggg ccgagttgcg cggctgggcg gagcgcgggt tcgccgccgt cgcgcaggac
     3661 gtgcgcggcc ggcacggctc ggcgggggag tggcacccgt accgcgacca cgaggccgag
     3721 gacggcgtgg ccacgctgga ctggatacgc gcccagccgt ggagcgacgg ccgcgtggtc
     3781 gccgccgggg cctcgtacgc cgcgtactgc gccctcgccg ccgccctctg ccccggcgcc
     3841 cgaggcccgg acgcggtgat cgccgccgtc cctgccctcg gcctcgccga gacggcccgc
     3901 gaacccaccg gaccggaacg cctctgggcc cgcctcggct ggtgggcggc ccacggcgac
     3961 cggcgcgact ccgcacccga cgccctcgac cgcgccctcg cccgggaccc gagcctgccc
     4021 acgcacctgc cgctgacccg gatcgcggac cggctcgacc gccaactccc gtcctggccc
     4081 gcgctgtggg cggactgccg gcgtgggcgc ctggtcgccc acggctccgc cgcccggctc
     4141 ccgctgctcg ccgtcggcgg cacccgcgac cccttcgccg aggacaccgt cgccctctgg
     4201 cgcggctggg gcggccccgc ccggctgctg ctcggcccgt ggggccacac cctcacggcg
     4261 gagacccgcc ccggcacccc gggccgcgtc gacctcggcg ccctctacgc ccgctgggcc
     4321 cgggccgcgc tcgacggaga actcggtccc gggcggcgcg gcgtcatcgg cctcgcggag
     4381 agcggacgct ggcaccacct cacggacacc ccgacccggc ccgaagggcc cgaagtggcg
     4441 ggctgtgtat ggcagttcgg tgccgccaac ggccggtgtc tgctcgccgg cgccgagttc
     4501 accgccgacc cggaccgccc cgtccgctcc gacgacctca ccgttccgcg tggggccccc
     4561 gccgaccgct gcctgctcgc caccccgccg ctgccccgcc ccctcgacct ggcgggcccc
     4621 gccgaggccc ggctcaccgt cgtcgcggac acgccccgcg ccgactgggc ggtccgcgtc
     4681 gtcgccctcg acccggccgg acgcgccgat cccctcgcct tcggcatcgt ccggcgcgac
     4741 gccccgcccg gcaccccgca ccccgtcacc gtgccgctcg ggaccctcgg gcggaccctg
     4801 gccgccggga ccaggctgcg cgtcgagatc gccggccatc acttccccgc gcacgcccgc
     4861 aacccgcaca ccggcgagga ccccgtcacc gccacccgcc tggccgcctc ccgccgcacc
     4921 gtccgcagcg agggcagcgc cctccacctg cccgtggccg gccgcccccg ccccgtcgac
     4981 cccgtaccgg agacctgccg atgaccgccg ccctgcccct cgacgccctc gtcgaccccc
     5041 actgcggact cgtccgcgac gtcgcgcccg tcccgcaccc cgagggcgcg ccaccccgct
     5101 acaccgccat gaccgcgcac gtcgccgacg cccgccggtt cggcgcctgg cccgccgacc
     5161 gggtctcgct cggcaccacc ttcggcgacc cggccggtgc ctggaccgcc gccgtcgccg
     5221 aggccgtcga acggtactgc ggcaaccggc tcccgccgcc cggccacccc gacgcacccc
     5281 gccgcgccac cgccgcccag ctcaccgccg agggacacca ggtgtacggc ccggacgacg
     5341 tgcccgccta cgcgccctgg cagtaccgcc gccccgcctt cccctacgcc ccgctcacgc
     5401 ccggcacccc cgctctctgg gcgcggggca cggagaacgg ccgcgactgc tgggcgccgg
     5461 tcgccctcac ccacctcaac tggcgccagg gagaactgcg tgcactgccg cgcacccacc
     5521 acctcaacta cgcgggcatc gccaccggac agggactcgc cgacgccgcc gaacgcgccc
     5581 tcctcgaagt ggtcgagcgg gacgccctcg aactgtggtg gcacctggac gggcccaccc
     5641 ggggcgtcga ccccggcagc gtccccgggc tcgacgccga cctcgccggg tccggcctgg
     5701 aggtgagcat cgtcgagatg ccctcggagt tcgcgccctg cgtggccgcc ctggtccacg
     5761 acgcccggcg gggtgtccac gcggccggtt tcgcctgccg cttcgacccg gccgaagccg
     5821 cccgcaaggc cgtcctggaa gccgtccaca cctgggtctt caccctgggc gccgaagccg
     5881 ccggcggctg ggtgcaccag gccgtcgagg ccggcgtcct ggcccgcggc ctctacctgg
     5941 accaccgggc cgaccgccgc tacctcgacg actgcggcga ggagttcgcc gccgtacggg
     6001 acctcggcgc ccacgtccag gcatggctcg acccgcgcct cgcccccctc gcccgccgct
     6061 tcaccgcacc cgccctcggg accgtccccg tcgccgagct cgcgcccgga agccgggagc
     6121 ggctcgatgc cgccctcgcg gcgggcggcc accgcgtcct caccttcgac ctgaccgccg
     6181 aggacgtcgc cgggaccgcc ctgcgcgtcg cccgcgtcct ggtcggcggc ctcgtcccca
     6241 acgcccccgc cgccttcggc tactacggct gcccccgctt cgccaccgcc gccctcgccc
     6301 ggggctggcg caccgaaccc ccgcgcgccc ccgccgactt caccctcgcc cccgccccgc
     6361 acatgtgacc cccggctccc ccatgacccc tgacgccacc ctcggccacg ccctcgccct
     6421 cgccagatca ccccgcaccc cggcccgcgc caccccgccc ccgcgccgcc cctacccctg
     6481 gaccggcacc ccgctcgccc tccccgccac cgcccccgac cccgacggcc ccgtcgacct
     6541 cgaccacctg ctgcgccact ccctgcgcgc ccgccccggc cccggtggcc ggttccggcc
     6601 cgccgcctcc gccggggccc tccacccggt ccgcgcccac cttctgatcg gccccggctg
     6661 caccctgccc ccggggcggt acgcctacga cgccgaggtc caccgggtgt tccggcgcgg
     6721 cccggcaccc cggggagcgg cccccggcgt gatcgccgtc ctcaccgtca ccgccgccca
     6781 caccgccgcc cactacggcc accgcgcctg gcccctgctg ctcctcgaca ccggccatac
     6841 ggccgccgcc ctcgccctcg ccccgaaggg acccggcgtc cgcgtcagcc tcgacaccga
     6901 cgccgccacg ctcgcggccg cggccgggct gcccccggcc gaccgctggc agcggatacg
     6961 gccgggcacc gagaccgaac accccctcgc cgccgtccag gtgacgcccc gccgcaccca
     7021 gcgcaccgcc cccgccctcg accgctgggc ggccctgccg ctcccgcacc gcacccgcac
     7081 ccccacccgg cccccggccc ggccctgcgg caccggccgc ctgctggaac tgctgggcgc
     7141 cgccaccggg accgaactgg cctggcaccc cgtccgccgc cccgccaccg tcaccggacg
     7201 cgccctgctg gagcgccgca gcgccgaccc cgccgccctg ggccacccgc cggacgggga
     7261 gacggtggcc cgcctgctgc acaccgccgc caccgcctgg ccgggcggcc ccgcctggtg
     7321 cgccgccgtc gccacccccg cccccgccct gctcgccccc ggccaccaca ccgccacccc
     7381 gtaccgcctc gcccggggcg acgcccgacc cagcctcgcc cactgggccg ccggccagct
     7441 ctggctcgcc gacaccggag cggcactcct cgcccacggc tgcccctcgg acgcccccgc
     7501 ctcccagatt cgccacgacc acctcgccgc cggcttcgcc gcgggcaccg cccacgccca
     7561 cgccgccgcc gagggaatca acgcccgccc cgtcggctcc tggcaacagg cggacctcgg
     7621 cgccgccctg ggcgacaccc cggggctcga ctgggtcctg cacggcctgg cactgggagc
     7681 cgcccgatga gccgccgccc acggcccccc cccgaccacc ccaccccgcc cggagagacg
     7741 tacccgcgat gatcccgccc cccgaactgc ggcgcgccgc ccggcccgcc gccctgccac
     7801 tggccggggc cactgccctg ctcgccctgg tcggcgccac ccacatcggg caggcggtgc
     7861 tgctcgctct cgtactcgcc cgcgtggccc ggggcgagac ggccgggctg cccgcgctgc
     7921 tcgccgccgt ggccgtcgtc gtactggccc gcgcgctgct cagccgcgcc cagcggctgc
     7981 tggccgtccg cgccggagcc ctggtccgcg tccgcctccg cgacgacctc ctcgcccacc
     8041 tcggccggac cggcccgggg gcgctcagcg gagcccgggc gggagcggtc cgggccaccc
     8101 tcgtcgacgg cgtcgagggc gtggacgcgt acgtctcccg ctacctgccc catctgatcg
     8161 tcacctgcgc cctcccgccc cggctgctgg tcgccgtcgc cctcgtcgag ccgtacgccg
     8221 tggccgcact cgcccccgcc ctcctgctgg cgctcgccgg gccccgcctc tgggaccggc
     8281 tcctcgcccg ccggggccgc gagcactggg actcctacga ggcgctcgcc gccgaccacc
     8341 tggaggccct ccaggggatg gcgaccctgc gcgccgcagg cgccgtcggc cgcacccagg
     8401 cccggctgga gcggcgatcg gccgcgctgc accgggccac cgtggccaag atgcgggtct
     8461 ccctcgccga caccggcctc accgacctcg ccgtgcaggg cggcaccgtc gccgccgtcc
     8521 tcgtcgcctg cgccgcagcc accaccggga gcaccaccgc gaccggcacc tacctgctgc
     8581 tgatgctggc ctccgagtgc ttccgcccgg tccgcgacct ctcccgcgag tggcacgccg
     8641 ggcacctggg gctgtcggcc gtcgacggca ttgccgcgct gcgccacacc gagggcggcg
     8701 tccccgacga gggcaccgcc cccgccgaat gggccacacc ccccgaagta cggttcgaga
     8761 acgtccactt cacccacccg ggccggaccc cccccgccct cgcaggcgtc gccttcaccg
     8821 ccccggccgg acgcgtcacc gccctggtcg gcccctccgg cgccggaaag tccaccctgc
     8881 tgagcctcct gctccgccag cgcgaccccg acgccggccg gatcaccgtc ggcggcctgg
     8941 acaccgccgc gtaccggctg gacgcgctcc gccggggcat cgccgtggtc tcccaggaca
     9001 cctacctctt ccgcgccagc gtcgccgaca acctccgcct cgcccgcccc gccgccaccc
     9061 cgtcccagct ccacgaggcc gcccgcgccg ccggcatcca cgaggagctg acccggctcc
     9121 ccgacgggta cgacacggtg atcggcgaac gcggcgccac tctctccggc ggccagcggc
     9181 agcgcctcgc cctggcccgc gccctgctcg ccgacgcccc ggtcctcctc ctcgacgagg
     9241 ccaccagcgc cgtggacgaa cgcgccgagg cccgcatcac ccgggaactc ctggccgccg
     9301 gacggggccg cacctgcctg ctcgtcgccc accgcctcga agccgtccgc cacgccgacc
     9361 acatcgtcgt cctcgaccac ggccgcgtcg aggccgccgg gacccacccc caactcctcg
     9421 ccgccggcgg cctgtacgcc cgcctggtcg ccgcgggccg caccgtcacc ccgatgcagc
     9481 aggaggccgc atgaccccgc ccgcaccgca ggagccaccg gccggcccgc ccacgcgcaa
     9541 agccctgcgc tcactgctgc ccgtgctcgc cgcccaccgc gccatgaccg cccgtacctg
     9601 tgcggccgcc ctcgtcgacc aggcggccct cgtcgccctc gtcaccctcg ccgcccacac
     9661 cgtcggaacg gccgtgatcg acgggcggcc cccctcaacc gccaccgccg cgctgctcct
     9721 tgccctggtc gccgtgcgcg ccctggccac ctggcgcgag atggacctct cccacgacct
     9781 cgcctaccgg gtcctcgccc tcctgcgcgt ccgcgtcttc gacgggatcg cccgcagcgc
     9841 ccccgcccgc attgccggac gccgcagcgg cgacctcgcc tccaccgcgc tgggcgacgt
     9901 cgaggcgctg gagttcttct acgcccacgc cctcgcccaa ctcctcgcca ccggaacggt
     9961 gttcaccgcc tcggcggccc tgctgggcac ccgcgaaccc tggctgctcg ccctcctcct
    10021 gcccgccgcc gcgctcctgc tcgccctgcc cgtcctcgac ggacggggcc gcgccgcacg
    10081 aggagcccgc acccgcacgg ccctcgccga cctctccgcc gagaccgtgg agaccgtcga
    10141 cgggctgcgc gaactcctcg ccttcggcgc gctgcaccgc cggcgcgccc gcctgcgcgc
    10201 gtacgggcgg cggctggccc gcgcgcaacg ggccgagcag tcctgggagg ccggtgccgc
    10261 cgccctccgc gacctgctgg tggtggccgc cgtgatcggc gtcgtcgccg tcgccggcca
    10321 cagcgccgtc gagggccgcc tgcacggcgc ctggaccccg gccgcgatgg ccctggcgct
    10381 cggcgccctc gcccctgtcg ccgacgccgc cgcctcgctc gggcaggccg gcagcctgcg
    10441 tgccgccgcc gcccgggtgc gcgccgccgc cgaagccccc gccggcgccc ccgcgccgag
    10501 cacaccgcgc ccgctgcccg agggacccct cggccttcac ctgcgtggcg tgcgcttcgg
    10561 gtacggctcc acacccgtgc tggacggggt ggacctcacc gtccgtccgg gcgagaccgt
    10621 cgccctggtc ggcgcctccg gcgcgggcaa gtccacctgc gcgcacctcc tggcccgcta
    10681 ctgggacccc caggaaggca ccgtcaccct cgtccccgag gacggacggc caccggtcgc
    10741 cctgcgggac ctggccgacg ccgagctgcg cagcgccgtc gccgtcgtcg gccaggaagc
    10801 ccccctcttc cacggcaccc tcgccgagaa cctgctgctg gccgcccccg acgccccgcc
    10861 ggacgcgctg gaccgcgccg tccgggcctg cggcgtcgat gtcctcgccg ccggactccc
    10921 cgacggtctc ggtacggccg tgggggagcg gggtgccacc ctctccggcg gacagcgggc
    10981 ccgagtggcc ctggcgcggg ccctggtcgc cgctccccgc gtactggtcc tggacgagac
    11041 cacggcccac ctggaccaca ccggggacgc ggaactcgcc gccgccctcg ccgccacggc
    11101 ccccgggcgc gccacgctgg tcatcgccca ccggcccgcg accgtgcgcc gggccgaccg
    11161 cgtcgccgtc ctggaggacg gccggatcgt ggaggagggc acctggcagg agctggcctc
    11221 cgccggcggc gcgctgaccc gcctgctctc cagggaggcg acggcaaccg cctgacccgc
    11281 accgaagcgt gcgtgcacgc gcacgcacac gtgaaagagc cggggcccct cgcggggacc
    11341 ccggctcctc ggtccggtga aggagtgc
//
